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Olen nõus

Andrew Paul Morris

https://www.etis.ee/CV/Andrew Paul_Morris/est
17.05.1973
+44 (0)161 306 8732
andrew.morris-5@manchester.ac.uk

Teenistuskäik

Töökohad ja ametid
01.06.2019–...   
University of Manchester, Professor (1,00)
01.05.2010–...   
Tartu Ülikool, Tartu Ülikooli Eesti Geenivaramu, Professor (0,05)
01.01.2014–31.05.2019   
University of Liverpool, Professor of Statistical Genetics (1,00)
01.07.2007–30.06.2017   
University of Liverpool, Wellcome Trust Senior Research Fellow (1,00)
01.01.2005–31.12.2007   
Wellcome Trust Centre for Human Genetics, University of Oxford. Funded by The Leverhulme Trust. Leverhulme Early Career Fellow
01.01.2001–31.12.2007   
Wellcome Trust Centre for Human Genetics, University of Oxford. Funded by The Wellcome Trust, Research Scientist
01.01.1998–31.12.2000   
Department of Applied Statistics, University of Reading. Funded by Pfizer Central Research Limited, UK. Research Fellow
01.01.1994–31.12.1994   
Human Genetics Research Division, University of Southampton. Research Assistant
 
 
Haridustee
1995–1998   
Doktoriõpe Readingi Ülikoolis
1994–1995   
Magistriõpe Readingi Ülikoolis
1991–1994   
Bakalaureuseõpe Readingi Ülikoolis
 
 
Teadusorganisatsiooniline ja -administratiivne tegevus
2020−...   
MRC Non-clinical Career Development Panel
2019−...   
Associate Editor, Frontiers in Genetics
2017−...   
Clinical Practice Research Datalink (CPRD), Independent Scientific Advisory Committee Professional Member
2015−...   
Member of the editorial board of eLife Science
2014−...   
Section Editor, Current Diabetes Reports
2010−...   
Member of the editorial board of Genetic Epidemiology.
2010−...   
Course organiser for the Wellcome Trust Advanced Course "Design and Analysis of Genetic-based Association Studies" with Prof. Heather Cordell (University of Newcastle) and Dr. Jonathan Marchini (University of Oxford).
2018−2018   
Past President, International Genetic Epidemiology Society
2017−2017   
President, International Genetic Epidemiology Society
2016−2016   
President Elect, International Genetic Epidemiology Society
2014−2018   
Member of the editorial board of Scientific Reports
2012−2018   
Member of the board of directors of the International Genetic Epidemiology Society
2011−2011   
Co-editor "Analysis of Complex Disease Association Studies" with Dr. Eleftheria Zeggini (Wellcome Trust Sanger Institute)
2010−2010   
Course Director for Wellcome Trust Doctoral Programme in Genomic Medicine and Statistics at the University of Oxford.
2010−2010   
Host and organiser of the 2010 European Mathematical Genetics Meeting at the University of Oxford

Kvalifikatsioon

Teaduskraadid
Andrew Paul Morris, doktorikraad, 1998, (juh) Robert Curnow; John Whittaker, Linkage and association methods for locating disease genes, University of Reading.
 
 
Teaduspreemiad ja tunnustused
2010, Andrew Paul Morris, Geneetilise epidemioloogia parim artikkel 2010: “A powerful approach to sub-phenotype analysis in population-based genetic association studies”.
 
 
Teadustöö põhisuunad
ETIS KLASSIFIKAATOR: 1. Bio- ja keskkonnateadused; 1.3. Geneetika; CERCS KLASSIFIKAATOR: B220 Geneetika, tsütogeneetika

Jooksvad projektid

Lõppenud projektid

Juhendamisel väitekirjad

Juhendatud väitekirjad

Publikatsioonid

Klass
Aasta
Publikatsioon
 
1.1.
2020
Zhu, Bangfu; Mak, Jennifer C. H.; Morris, Andrew P.; Marson, Anthony G.; Barclay, Jeff W.; Sills, Graeme J.; Morgan, Alan (2020). Functional analysis of epilepsy-associated variants in STXBP1/Munc18-1 using humanized Caenorhabditis elegans. Epilepsia. DOI: 10.1111/epi.16464.
1.1.
2020
Thompson, Andrew; Cook, James; Choquet, Helene; Jorgenson, Eric; Yin, Jie; Kinnunen, Tarja; Barclay, Jeff; Morris, Andrew P.; Pirmohamed, Munir (2020). Functional validity, role, and implications of heavy alcohol consumption genetic loci. Science Advances, 6 (3), ARTN eaay5034. DOI: 10.1126/sciadv.aay5034.
1.1.
2020
Shah, Sonia; Henry, Albert; Roselli, Carolina; Lin, Honghuang; Sveinbjornsson, Gardar; Fatemifar, Ghazaleh; Hedman, Asa K.; Wilk, Jemma B.; Morley, Michael P.; Chaffin, Mark D.; Helgadottir, Anna; Verweij, Niek; Dehghan, Abbas; Almgren, Peter; Andersson, Charlotte; Aragam, Krishna G.; Arnlov, Johan; Backman, Joshua D.; Biggs, Mary L.; Bloom, Heather L. ... Ye, Bin (2020). Genome-wide association and Mendelian randomisation analysis provide insights into the pathogenesis of heart failure. Nature Communications, 11 (1), ARTN 163. DOI: 10.1038/s41467-019-13690-5.
1.1.
2020
Turner, Richard M.; Fontana, Vanessa; FitzGerald, Richard; Morris, Andrew P.; Pirmohamed, Munir (2020). Investigating the clinical factors and comedications associated with circulating levels of atorvastatin and its major metabolites in secondary prevention. British Journal of Clinical Pharmacology, 86 (1), 62−74. DOI: 10.1111/bcp.14133.
1.1.
2019
de Vries, Paul S.; Brown, Michael R.; Bentley, Amy R.; Sung, Yun J.; Winkler, Thomas W.; Ntalla, Ioanna; Schwander, Karen; Kraja, Aldi T.; Guo, Xiuqing; Franceschini, Nora; Cheng, Ching-Yu; Sim, Xueling; Vojinovic, Dina; Huffman, Jennifer E.; Musani, Solomon K.; Li, Changwei; Feitosa, Mary F.; Richard, Melissa A.; Noordam, Raymond; Aschard, Hugues ... Morrison, Alanna C. (2019). Multiancestry Genome-Wide Association Study of Lipid Levels Incorporating Gene-Alcohol Interactions. American Journal of Epidemiology, 188 (6), 1033−1054. DOI: 10.1093/aje/kwz005.
1.1.
2019
Bentley, Amy R; Sung, Yun J; Brown, Michael R; Winkler, Thomas W; Kraja, Aldi T; Ntalla, Ioanna; Schwander, Karen; Chasman, Daniel I; Lim, Elise; Deng, Xuan; Guo, Xiuqing; Liu, Jingmin; Lu, Yingchang; Cheng, Ching-Yu; Sim, Xueling; Vojinovic, Dina; Huffman, Jennifer E; Musani, Solomon K; Li, Changwei; Feitosa, Mary F ... Cupples, L Adrienne (2019). Multi-ancestry genome-wide gene-smoking interaction study of 387,272 individuals identifies new loci associated with serum lipids. Nature Genetics, 51 (4), 636−648. DOI: 10.1038/s41588-019-0378-y.
1.1.
2019
Kilpelainen, Tuomas O.; Bentley, Amy R.; Noordam, Raymond; Sung, Yun Ju; Schwander, Karen; Winkler, Thomas W.; Jakupovic, Hermina; Chasman, Daniel I.; Manning, Alisa; Ntalla, Ioanna; Aschard, Hugues; Brown, Michael R.; de las Fuentes, Lisa; Franceschini, Nora; Guo, Xiuqing; Vojinovic, Dina; Aslibekyan, Stella; Feitosa, Mary F.; Kho, Minjung; Musani, Solomon K. ... Loos, Ruth J. F. (2019). Multi-ancestry study of blood lipid levels identifies four loci interacting with physical activity. Nature Communications, 10, ARTN 376. DOI: 10.1038/s41467-018-08008-w.
1.1.
2019
Harold, Denise; Connolly, Siobhan; Riley, Brien P.; Kendler, Kenneth S.; McCarthy, Shane E.; McCombie, William R.; Richards, Alex; Owen, Michael J.; O'Donovan, Michael C.; Walters, James; Donnelly, Peter; Bates, Lesley; Barroso, Ines; Blackwell, Jenefer M.; Bramon, Elvira; Brown, Matthew A.; Casas, Juan P.; Corvin, Aiden; Deloukas, Panos; Duncanson, Audrey ... Morris, Derek W. (2019). Population-based identity-by-descent mapping combined with exome sequencing to detect rare risk variants for schizophrenia. American Journal of Medical Genetics Part B Neuropsychiatric Genetics, 180 (3), 223−231. DOI: 10.1002/ajmg.b.32716.
1.1.
2019
Shrine, Nick; Guyatt, Anna L.; Erzurumluoglu, A. Mesut; Jackson, Victoria E.; Hobbs, Brian D.; Melbourne, Carl A.; Batini, Chiara; Fawcett, Katherine A.; Song, Kijoung; Sakornsakolpat, Phuwanat; Li, Xingnan; Boxall, Ruth; Reeve, Nicola F.; Obeidat, Ma'en; Zhao, Jing Hua; Wielscher, Matthias; Weiss, Stefan; Kentistou, Katherine A.; Cook, James P.; Sun, Benjamin B. ... Wain, Louise, V (2019). New genetic signals for lung function highlight pathways and chronic obstructive pulmonary disease associations across multiple ancestries. Nature Genetics, 51 (3), 481−497.10.1038/s41588-018-0321-7.
1.1.
2019
Doerr, Marcus; Hamburg, Naomi M.; Mueller, Christian; Smith, Nicholas L.; Gustafsson, Stefan; Lehtimaeki, Terho; Teumer, Alexander; Zeller, Tanja; Li, Xiaohui; Lind, Lars; Raitakari, Olli T.; Voelker, Uwe; Blankenberg, Stefan; McKnight, Barbara; Morris, Andrew P.; Kaehoenen, Mika; Lemaitre, Rozenn N.; Wild, Philipp S.; Nauck, Matthias; Voelzke, Henry ... Schnabel, Renate B. (2019). Common Genetic Variation in Relation to Brachial Vascular Dimensions and Flow-Mediated Vasodilation. Circulation Genomic and Precision Medicine, 12 (2), ARTN e002409.10.1161/CIRCGEN.118.002409.
1.1.
2019
Justice, Anne E; Karaderi, Tugce; Highland, Heather M; Young, Kristin L; Graff, Mariaelisa; Lu, Yingchang; Turcot, Valérie; Auer, Paul L; Fine, Rebecca S; Guo, Xiuqing; Schurmann, Claudia; Lempradl, Adelheid; Marouli, Eirini; Mahajan, Anubha; Winkler, Thomas W; Locke, Adam E; Medina-Gomez, Carolina; Esko, Tõnu; Vedantam, Sailaja; Giri, Ayush ... Lindgren, Cecilia M (2019). Protein-coding variants implicate novel genes related to lipid homeostasis contributing to body-fat distribution. Nature Genetics, 51 (3), 452−469.10.1038/s41588-018-0334-2.
1.1.
2019
Gialluisi, Alessandro; Andlauer, Till F. M.; Mirza-Schreiber, Nazanin; Moll, Kristina; Becker, Jessica; Hoffmann, Per; Ludwig, Kerstin U.; Czamara, Darina; St Pourcain, Beate; Brandler, William; Honbolygo, Ferenc; Toth, Denes; Csepe, Valeria; Huguet, Guillaume; Morris, Andrew P.; Hulslander, Jacqueline; Willcutt, Erik G.; DeFries, John C.; Olson, Richard K.; Smith, Shelley D. ... Schulte-Koerne, Gerd (2019). Genome-wide association scan identifies new variants associated with a cognitive predictor of dyslexia. Translational Psychiatry, 9, ARTN 77.10.1038/s41398-019-0402-0.
1.1.
2019
Karasik, David; Zillikens, M. Carola; Hsu, Yi-Hsiang; Aghdassi, Ali; Akesson, Kristina; Amin, Najaf; Barroso, Ines; Bennett, David A.; Bertram, Lars; Bochud, Murielle; Borecki, Ingrid B.; Broer, Linda; Buchman, Aron S.; Byberg, Liisa; Campbell, Harry; Campos-Obando, Natalia; Cauley, Jane A.; Cawthon, Peggy M.; Chambers, John C.; Chen, Zhao ... Ohlsson, Claes (2019). Disentangling the genetics of lean mass. American Journal of Clinical Nutrition, 109 (2), 276−287.10.1093/ajcn/nqy272.
1.1.
2019
Morris, Andrew P.; Le, Thu H.; Wu, Haojia; Akbarov, Artur; van der Most, Peter J.; Hemani, Gibran; Smith, George Davey; Mahajan, Anubha; Gaulton, Kyle J.; Nadkarni, Girish N.; Valladares-Salgado, Adan; Wacher-Rodarte, Niels; Mychaleckyj, Josyf C.; Dueker, Nicole D.; Guo, Xiuqing; Hai, Yang; Haessler, Jeffrey; Kamatani, Yoichiro; Stilp, Adrienne M.; Zhu, Gu ... Franceschini, Nora (2019). Trans-ethnic kidney function association study reveals putative causal genes and effects on kidney-specific disease aetiologies. Nature Communications, 10, ARTN 29.10.1038/s41467-018-07867-7.
1.1.
2019
Pulit, Sara L.; Stoneman, Charli; Morris, Andrew P.; Wood, AndrewR.; Glastonbury, Craig A.; Tyrrell, Jessica; Yengo, Loic; Ferreira, Teresa; Marouli, Eirini; Ji, Yingjie; Yang, Jian; Jones, Samuel; Beaumont, Robin; Croteau-Chonka, Damien C.; Winkler, Thomas W.; Hattersley, Andrew T.; Loos, Ruth J. F.; Hirschhorn, Joel N.; Visscher, Peter M.; Frayling, Timothy M. ... Lindgren, Cecilia M. (2019). Meta-analysis of genome-wide association studies for body fat distribution in 694 649 individuals of European ancestry. Human Molecular Genetics, 28 (1), 166−174.10.1093/hmg/ddy327.
1.1.
2019
Wuttke, Matthias; Li, Yong; Li, Man; Sieber, Karsten B.; Feitosa, Mary F.; Gorski, Mathias; Tin, Adrienne; Wang, Lihua; Chu, Audrey Y.; Hoppmann, Anselm; Kirsten, Holger; Giri, Ayush; Chai, Jin-Fang; Sveinbjornsson, Gardar; Tayo, Bamidele O.; Nutile, Teresa; Fuchsberger, Christian; Marten, Jonathan; Cocca, Massimiliano; Ghasemi, Sahar ... Pattaro, Cristian (2019). A catalog of genetic loci associated with kidney function from analyses of a million individuals. Nature Genetics, 51 (6), 957−976. DOI: 10.1038/s41588-019-0407-x.
1.1.
2019
Gurdasani, Deepti; Carstensen, Tommy; Fatumo, Segun; Chen, Guanjie; Franklin, Chris S.; Prado-Martinez, Javier; Bouman, Heleen; Abascal, Federico; Haber, Marc; Tachmazidou, Ioanna; Mathieson, Iain; Ekoru, Kenneth; DeGorter, Marianne K.; Nsubuga, Rebecca N.; Finan, Chris; Wheeler, Eleanor; Chen, Li; Cooper, David N.; Schiffels, Stephen; Chen, Yuan ... Sandhu, Manj S. (2019). Uganda Genome Resource Enables Insights into Population History and Genomic Discovery in Africa. Cell, 179 (4), 984−1039. DOI: 10.1016/j.cell.2019.10.004.
1.1.
2019
Teumer, Alexander; Li, Yong; Ghasemi, Sahar; Prins, Bram P.; Wuttke, Matthias; Hermle, Tobias; Giri, Ayush; Sieber, Karsten B.; Qiu, Chengxiang; Kirsten, Holger; Tin, Adrienne; Chu, Audrey Y.; Bansal, Nisha; Feitosa, Mary F.; Wang, Lihua; Chai, Jin-Fang; Cocca, Massimiliano; Fuchsberger, Christian; Gorski, Mathias; Hoppmann, Anselm ... Koettgen, Anna (2019). Genome-wide association meta-analyses and fine-mapping elucidate pathways influencing albuminuria. Nature Communications, 10, ARTN 4130. DOI: 10.1038/s41467-019-11576-0.
1.1.
2019
Adeyemo, Adebowale A.; Zaghloul, Norann A.; Chen, Guanjie; Doumatey, Ayo P.; Leitch, Carmen C.; Hostelley, Timothy L.; Nesmith, Jessica E.; Zhou, Jie; Bentley, Amy R.; Shriner, Daniel; Fasanmade, Olufemi; Okafor, Godfrey; Eghan, Benjamin, Jr.; Agyenim-Boateng, Kofi; Chandrasekharappa, Settara; Adeleye, Jokotade; Balogun, William; Owusu, Samuel; Amoah, Albert; Acheampong, Joseph ... Motala, Ayesha A. (2019). ZRANB3 is an African-specific type 2 diabetes locus associated with beta-cell mass and insulin response. Nature Communications, 10, ARTN 3195. DOI: 10.1038/s41467-019-10967-7.
1.1.
2019
Romagnoni, Alberto; Jegou, Simon; Van Steen, Kristel; Wainrib, Gilles; Hugot, Jean-Pierre; Peyrin-Biroulet, Laurent; Chamaillard, Mathias; Colombel, Jean-Frederick; Cottone, Mario; D'Amato, Mauro; D'Inca, Renata; Halfvarson, Jonas; Henderson, Paul; Karban, Amir; Kennedy, Nicholas A.; Khan, Mohammed Azam; Lemann, Marc; Levine, Arie; Massey, Dunecan; Milla, Monica ... Whittaker, Pamela (2019). Comparative performances of machine learning methods for classifying Crohn Disease patients using genome-wide genotyping data. Scientific Reports, 9, ARTN 10351. DOI: 10.1038/s41598-019-46649-z.
1.1.
2019
Floyd, James S.; Bloch, Katarzyna M.; Brody, Jennifer A.; Maroteau, Cyrielle; Siddiqui, Moneeza K.; Gregory, Richard; Carr, Daniel F.; Molokhia, Mariam; Liu, Xiaoming; Bis, Joshua C.; Ahmed, Ammar; Liu, Xuan; Hallberg, Par; Yue, Qun-Ying; Magnusson, Patrik K. E.; Brisson, Diane; Wiggins, Kerri L.; Morrison, Alanna C.; Khoury, Etienne; McKeigue, Paul ... Delrieu, Olivier (2019). Pharmacogenomics of statin-related myopathy: Meta-analysis of rare variants from whole-exome sequencing. PLoS ONE, 14 (6), ARTN e0218115. DOI: 10.1371/journal.pone.0218115.
1.1.
2019
Spracklen, Cassandra N.; Karaderi, Tugce; Yaghootkar, Hanieh; Schurmann, Claudia; Fine, Rebecca S.; Kutalik, Zoltan; Preuss, Michael H.; Lu, Yingchang; Wittemans, Laura B. L.; Adair, Linda S.; Allison, Matthew; Amin, Najaf; Auer, Paul L.; Bartz, Traci M.; Blueher, Matthias; Boehnke, Michael; Borja, Judith B.; Bork-Jensen, Jette; Broer, Linda; Chasman, Daniel I. ... Mohlke, Karen L. (2019). Exome-Derived Adiponectin-Associated Variants Implicate Obesity and Lipid Biology. The American Journal of Human Genetics, 105 (1), 15−28. DOI: 10.1016/j.ajhg.2019.05.002.
1.1.
2019
Lin, Bridget M.; Nadkarni, Girish N.; Tao, Ran; Graff, Mariaelisa; Fornage, Myriam; Buyske, Steven; Matise, Tara C.; Highland, Heather M.; Wilkens, Lynne R.; Carlson, Christopher S.; Park, S. Lani; Setiawan, V. Wendy; Ambite, Jose Luis; Heiss, Gerardo; Boerwinkle, Eric; Lin, Dan-Yu; Morris, Andrew P.; Loos, Ruth J. F.; Kooperbere, Charles; North, Kari E. ... Franceschini, Nora (2019). Genetics of Chronic Kidney Disease Stages Across Ancestries: The PAGE Study. Frontiers in Genetics, 10, ARTN 494. DOI: 10.3389/fgene.2019.00494.
1.1.
2019
Flannick, Jason; Mercader, Josep M.; Fuchsberger, Christian; Udler, Miriam S.; Mahajan, Anubha; Wessel, Jennifer; Teslovich, Tanya M.; Caulkins, Lizz; Koesterer, Ryan; Barajas-Olmos, Francisco; Blackwell, Thomas W.; Boerwinkle, Eric; Brody, Jennifer A.; Centeno-Cruz, Federico; Chen, Ling; Chen, Siying; Contreras-Cubas, Cecilia; Cordova, Emilio; Correa, Adolfo; Cortes, Maria ... Boehnke, Michael (2019). Exome sequencing of 20,791 cases of type 2 diabetes and 24,440 controls. Nature, 570 (7759), 71−95. DOI: 10.1038/s41586-019-1231-2.
1.1.
2019
Nicoletti, Paola; Barrett, Sarah; McEvoy, Laurence; Daly, Ann K.; Aithal, Guruprasad; Isabel Lucena, M.; Andrade, Raul J.; Wadelius, Mia; Hallberg, Paer; Stephens, Camilla; Bjornsson, Einar S.; Friedmann, Peter; Kainu, Kati; Laitinen, Tarja; Marson, Anthony; Molokhia, Mariam; Phillips, Elizabeth; Pichler, Werner; Romano, Antonino; Shear, Neil ... Pirmohamed, Munir (2019). Shared Genetic Risk Factors Across Carbamazepine-Induced Hypersensitivity Reactions. Clinical Pharmacology & Therapeutics, 106 (5), 1028−1036. DOI: 10.1002/cpt.1493.
1.1.
2019
Warrington, Nicole M.; Beaumont, Robin N.; Horikoshi, Momoko; Day, Felix R.; Helgeland, Oyvind; Laurin, Charles; Bacelis, Jonas; Peng, Shouneng; Hao, Ke; Feenstra, Bjarke; Wood, Andrew R.; Mahajan, Anubha; Tyrrell, Jessica; Robertson, Neil R.; Rayner, N. William; Qiao, Zhen; Moen, Gunn-Helen; Vaudel, Marc; Marsit, Carmen J.; Chen, Jia ... Freathy, Rachel M. (2019). Maternal and fetal genetic effects on birth weight and their relevance to cardio-metabolic risk factors. Nature Genetics, 51 (5), 804−821. DOI: 10.1038/s41588-019-0403-1.
1.1.
2019
Chen, Ji; Sun, Meng; Adeyemo, Adebowale; Pirie, Fraser; Carstensen, Tommy; Pomilla, Cristina; Doumatey, Ayo P.; Chen, Guanjie; Young, Elizabeth H.; Sandhu, Manjinder; Morris, Andrew P.; Barroso, Ines; McCarthy, Mark I.; Mahajan, Anubha; Wheeler, Eleanor; Rotimi, Charles N.; Motala, Ayesha A. (2019). Genome-wide association study of type 2 diabetes in Africa. Diabetologia, 62 (7), 1204−1211. DOI: 10.1007/s00125-019-4880-7.
1.1.
2019
Middeldorp, Christel M.; Mahajan, Anubha; Horikoshi, Momoko; Robertson, Neil R.; Beaumont, Robin N.; Bradfield, Jonathan P.; Bustamante, Mariona; Cousminer, Diana L.; Day, Felix R.; De Silva, N. Maneka; Guxens, Monica; Mook-Kanamori, Dennis O.; St Pourcain, Beate; Warrington, Nicole M.; Adair, Linda S.; Ahlqvist, Emma; Ahluwalia, Tarunveer S.; Almgren, Peter; Ang, Wei; Atalay, Mustafa ... Felix, Janine F. (2019). The Early Growth Genetics (EGG) and EArly Genetics and Lifecourse Epidemiology (EAGLE) consortia: design, results and future prospects. European Journal of Epidemiology, 34 (3), 279−300. DOI: 10.1007/s10654-019-00502-9.
1.1.
2019
Sakornsakolpat, Phuwanat; Prokopenko, Dmitry; Lamontagne, Maxime; Reeve, Nicola F.; Guyatt, Anna L.; Jackson, Victoria E.; Shrine, Nick; Qiao, Dandi; Bartz, Traci M.; Kim, Deog Kyeom; Lee, Mi Kyeong; Latourelle, Jeanne C.; Li, Xingnan; Morrow, Jarrett D.; Obeidat, Ma'en; Wyss, Annah B.; Bakke, Per; Barr, R. Graham; Beaty, Terri H.; Belinsky, Steven A. ... Zeigler-Heitbrock, Loems (2019). Genetic landscape of chronic obstructive pulmonary disease identifies heterogeneous cell-type and phenotype associations. Nature Genetics, 51 (3), 494−508. DOI: 10.1038/s41588-018-0342-2.
1.1.
2019
Gallagher, C. S.; Makinen, N.; Harris, H. R.; Rahmioglu, N.; Uimari, O.; Cook, J. P.; Shigesi, N.; Ferreira, T.; Velez-Edwards, D. R.; Edwards, T. L.; Mortlock, S.; Ruhioglu, Z.; Day, F.; Becker, C. M.; Karhunen, V.; Martikainen, H.; Jarvelin, M. -R.; Cantor, R. M.; Ridker, P. M.; Terry, K. L. ... Wilson, Catherine H. (2019). Genome-wide association and epidemiological analyses reveal common genetic origins between uterine leiomyomata and endometriosis. Nature Communications, 10, ARTN 4857. DOI: 10.1038/s41467-019-12536-4.
6.8.
2019
Spracklen, Cassandra N.; Karaderi, Tugce; Yaghootkar, Hanieh; Schurmann, Claudia; Fine, Rebecca S.; Kutalik, Zoltan; Preuss, Michael H.; Lu, Yingchang; Wittemans, Laura B. L.; Adair, Linda S.; Allison, Matthew; Amin, Najaf; Auer, Paul L.; Bartz, Traci M.; Bluher, Matthias; Boehnke, Michael; Borja, Judith B.; Bork-Jensen, Jette; Broer, Linda; Chasman, Daniel I. ... Mohlke, Karen L. (2019). Exome-Derived Adiponectin-Associated Variants Implicate Obesity and Lipid Biology (vol 105, pg 15, 2019). The American Journal of Human Genetics, 105 (3), 670−671. DOI: 10.1016/j.ajhg.2019.08.001.
6.8.
2019
Shrine, Nick; Guyatt, Anna L.; Erzurumluoglu, A. Mesut; Jackson, Victoria E.; Hobbs, Brian D.; Melbourne, Carl A.; Batini, Chiara; Fawcett, Katherine A.; Song, Kijoung; Sakornsakolpat, Phuwanat; Li, Xingnan; Boxall, Ruth; Reeve, Nicola F.; Obeidat, Ma'en; Zhao, Jing Hua; Wielscher, Matthias; Weiss, Stefan; Kentistou, Katherine A.; Cook, James P.; Sun, Benjamin B. ... Wain, Louise V. (2019). New genetic signals for lung function highlight pathways and chronic obstructive pulmonary disease associations across multiple ancestries (vol 51, pg 481, 2019). Nature Genetics, 51 (6), 1067−1067. DOI: 10.1038/s41588-019-0438-3.
1.1.
2018
Sung, Yun J.; Winkler, Thomas W.; de las Fuentes, Lisa; Bentley, Amy R.; Brown, Michael R.; Kraja, Aldi T.; Schwander, Karen; Ntalla, Ioanna; Guo, Xiuqing; Franceschini, Nora; Lu, Yingchang; Cheng, Ching-Yu; Sim, Xueling; Vojinovic, Dina; Marten, Jonathan; Musani, Solomon K.; Li, Changwei; Feitosa, Mary F.; Kilpelainen, Tuomas O.; Richard, Melissa A. ... Chasman, Daniel I. (2018). A Large-Scale Multi-ancestry Genome-wide Study Accounting for Smoking Behavior Identifies Multiple Significant Loci for Blood Pressure. The American Journal of Human Genetics, 102 (3), 375−400. DOI: 10.1016/j.ajhg.2018.01.015.
1.1.
2018
Anttila, Verneri; Bulik-Sullivan, Brendan; Finucane, Hilary K.; Walters, Raymond K.; Bras, Jose; Duncan, Laramie; Escott-Price, Valentina; Falcone, Guido J.; Gormley, Padhraig; Malik, Rainer; Patsopoulos, Nikolaos A.; Ripke, Stephan; Wei, Zhi; Yu, Dongmei; Lee, Phil H.; Turley, Patrick; Grenier-Boley, Benjamin; Chouraki, Vincent; Kamatani, Yoichiro; Berr, Claudine ... (2018). Analysis of shared heritability in common disorders of the brain. Science, 360 (6395). DOI: 10.1126/science.aap8757.
1.1.
2018
Mahajan, Anubha; Taliun, Daniel; Thurner, Matthias; Robertson, Neil R.; Torres, Jason M.; Rayner, N. William; Payne, Anthony J.; Steinthorsdottir, Valgerdur; Scott, Robert A.; Grarup, Niels; Cook, James P.; Schmidt, Ellen M.; Wuttke, Matthias; Sarnowski, Chloe; Magill, Reedik; Nano, Jana; Gieger, Christian; Trompet, Stella; Lecoeur, Cecile; Preuss, Michael H. ... McCarthy, Mark, I (2018). Fine-mapping type 2 diabetes loci to single-variant resolution using high-density imputation and islet-specific epigenome maps. Nature Genetics, 50 (11), 1505−1516. DOI: 10.1038/s41588-018-0241-6.
1.1.
2018
Ligthart, Symen; Vaez, Ahmad; Võsa, Urmo; Stathopoulou, Maria G; de Vries, Paul S; Prins, Bram P; Van der Most, Peter J; Tanaka, Toshiko; Naderi, Elnaz; Rose, Lynda M; Wu, Ying; Karlsson, Robert; Barbalic, Maja; Lin, Honghuang; Pool, René; Zhu, Gu; Macé, Aurélien; Sidore, Carlo; Trompet, Stella; Mangino, Massimo ... Alizadeh, Behrooz Z (2018). Genome Analyses of >200,000 Individuals Identify 58 Loci for Chronic Inflammation and Highlight Pathways that Link Inflammation and Complex Disorders. The American Journal of Human Genetics, 103 (5), 691−706.10.1016/j.ajhg.2018.09.009.
1.1.
2018
Ruderfer, Douglas M.; Ripke, Stephan; McQuillin, Andrew; Boocock, James; Stahl, Eli A.; Pavlides, Jennifer M. Whitehead; Mullins, Niamh; Charney, Alexander W.; Ori, Anil P. S.; Loohuis, Loes M. Olde; Domenici, Enrico; Di Florio, Arianna; Papiol, Sergi; Kalman, Janos L.; Trubetskoy, Vassily; Adolfsson, Rolf; Agartz, Ingrid; Agerbo, Esben; Akil, Huda; Albani, Diego ... Kendler, Kenneth S. (2018). Genomic Dissection of Bipolar Disorder and Schizophrenia, Including 28 Subphenotypes. Cell, 173 (7), ARTN 1715.e16−1732. DOI: 10.1016/j.cell.2018.05.046.
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2018
Roselli, Carolina; Chaffin, Mark D; Weng, Lu-Chen; Aeschbacher, Stefanie; Ahlberg, Gustav; Albert, Christine M; Almgren, Peter; Alonso, Alvaro; Anderson, Christopher D; Aragam, Krishna G; Arking, Dan E; Barnard, John; Bartz, Traci M; Benjamin, Emelia J; Bihlmeyer, Nathan A; Bis, Joshua C; Bloom, Heather L; Boerwinkle, Eric; Bottinger, Erwin B; Brody, Jennifer A ... Ellinor, Patrick T (2018). Multi-ethnic genome-wide association study for atrial fibrillation. Nature Genetics, 50 (9), 1225−1233.10.1038/s41588-018-0133-9.
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2018
Feitosa, Mary F; Kraja, Aldi T; Chasman, Daniel I; Sung, Yun J; Winkler, Thomas W; Ntalla, Ioanna; Guo, Xiuqing; Franceschini, Nora; Cheng, Ching-Yu; Sim, Xueling; Vojinovic, Dina; Marten, Jonathan; Musani, Solomon K; Li, Changwei; Bentley, Amy R; Brown, Michael R; Schwander, Karen; Richard, Melissa A; Noordam, Raymond; Aschard, Hugues ... Levy, Daniel (2018). Novel genetic associations for blood pressure identified via gene-alcohol interaction in up to 570K individuals across multiple ancestries. PLoS ONE, 13 (6), e0198166−e0198166. DOI: 10.1371/journal.pone.0198166.
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2018
Mahajan, Anubha; Wessel, Jennifer; Willems, Sara M; Zhao, Wei; Robertson, Neil R; Chu, Audrey Y; Gan, Wei; Kitajima, Hidetoshi; Taliun, Daniel; Rayner, N William; Guo, Xiuqing; Lu, Yingchang; Li, Man; Jensen, Richard A; Hu, Yao; Huo, Shaofeng; Lohman, Kurt K; Zhang, Weihua; Cook, James P; Prins, Bram Peter ... McCarthy, Mark I (2018). Refining the accuracy of validated target identification through coding variant fine-mapping in type 2 diabetes. Nature Genetics, 50 (4), 559−571. DOI: 10.1038/s41588-018-0084-1.
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2018
de Jong, Simone; Abdalla Diniz, Mateus Jose; Saloma, Andiara; Gadelha, Ary; Santoro, Marcos L.; Ota, Vanessa K.; Noto, Cristiano; Curtis, Charlesg; Newhouse, Stephen J.; Patel, Hamel; Hall, Lynsey S.; O'Reilly, Paul F.; Belangero, Sintia, I; Bressan, Rodrigo A.; Breen, Gerome; Wray, Naomi R.; Ripke, Stephan; Mattheisen, Manuel; Trzaskowski, Maciej; Byrne, Enda M. ... Shi, Jianxin (2018). Applying polygenic risk scoring for psychiatric disorders to a large family with bipolar disorder and major depressive disorder. Communications Biology, 1, ARTN 163. DOI: 10.1038/s42003-018-0155-y.
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2018
Evangelou, Evangelos; Warren, Helen R.; Mosen-Ansorena, David; Mifsu, Borbala; Pazoki, Raha; Gao, He; Ntritsos, Georgios; Dimou, Niki; Cabrer, Claudia P.; Karaman, Ibrahim; Ng, FuLiang; Evangelou, Marina; Witkowska, Katarzyna; Tzanis, Evan; Hellwege, Jacklyn N.; Giri, Ayush; Edwards, Digna R. Velez; Sun, Yan, V; Cho, Kelly; Gaziano, J. Michael ... Caulfield, Mark J. (2018). Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits. Nature Genetics, 50 (10), 1412−1429. DOI: 10.1038/s41588-018-0205-x.
1.1.
2018
Marklund, Matti; Morris, Andrew P.; Mahajan, Anubha; Ingelsson, Erik; Lindgren, Cecilia M.; Lind, Lars; Riserus, Ulf (2018). Genome-Wide Association Studies of Estimated Fatty Acid Desaturase Activity in Serum and Adipose Tissue in Elderly Individuals: Associations with Insulin Sensitivity. Nutrients, 10 (11), ARTN 1791.10.3390/nu10111791.
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2018
Jackson, Victoria E.; Latourelle, Jeanne C.; Wain, Louise V.; Smith, Albert V.; Grove, Megan L.; Bartz, Traci M.; Obeidat, Ma'en; Province, Michael A.; Gao, Wei; Qaiser, Beenish; Porteous, David J.; Cassano, Patricia A.; Ahluwalia, Tarunveer S.; Grarup, Niels; Li, Jin; Altmaier, Elisabeth; Marten, Jonathan; Harris, Sarah E.; Manichaikul, Ani; Pottinger, Tess D. ... London, Stephanie J. (2018). Meta-analysis of exome array data identifies six novel genetic loci for lung function. Wellcome Open Research, 3, 166−174. DOI: 10.12688/wellcomeopenres.12583.3.
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2018
Fryett, James J.; Inshaw, Jamie; Morris, Andrew P.; Cordell, Heather J. (2018). Comparison of methods for transcriptome imputation through application to two common complex diseases. European Journal of Human Genetics, 26 (11), 1658−1667.10.1038/s41431-018-0176-5.
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2018
Gusarova, Viktoria; O'Dushlaine, Colm; Teslovich, Tanya M.; Benotti, Peter N.; Mirshahi, Tooraj; Gottesman, Omri; Van Hout, Cristopher V.; Murray, Michael F.; Mahajan, Anubha; Nielsen, Jonas B.; Fritsche, Lars; Wulff, Anders Berg; Gudbjartsson, Daniel F.; Sjogren, Marketa; Emdin, Connor A.; Scott, Robert A.; Lee, Wen-Jane; Small, Aeron; Kwee, Lydia C.; Dwivedi, Om Prakash ... Gromada, Jesper (2018). Genetic inactivation of ANGPTL4 improves glucose homeostasis and is associated with reduced risk of diabetes. Nature Communications, 9, ARTN 2252.10.1038/s41467-018-04611-z.
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2018
Small, Kerrin S.; Todorcevic, Marijana; Civelek, Mete; Moustafa, Julia S. El-Sayed; Wang, Xiao; Simon, Michelle M.; Fernandez-Tajes, Juan; Mahajan, Anubha; Horikoshi, Momoko; Hugill, Alison; Glastonbury, Craig A.; Quaye, Lydia; Neville, Matt J.; Sethi, Siddharth; Yon, Marianne; Pan, Calvin; Che, Nam; Vinuela, Ana; Tsai, Pei-Chien; Nag, Abhishek ... McCarthy, Mark I. (2018). Regulatory variants at KLF14 influence type 2 diabetes risk via a female-specific effect on adipocyte size and body composition. Nature Genetics, 50 (4), 572−584.10.1038/s41588-018-0088-x.
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2018
Jiang, Jiyang; Thalamuthu, Anbupalam; Ho, Jennifer E.; Mahajan, Anubha; Ek, Weronica E.; Brown, David A.; Breit, Samuel N.; Wang, Thomas J.; Gyllensten, Ulf; Chen, Ming-Huei; Enroth, Stefan; Januzzi, James L., Jr.; Lind, Lars; Armstrong, Nicola J.; Kwok, John B.; Schofield, Peter R.; Wen, Wei; Trollor, Julian N.; Johansson, Asa; Morris, Andrew P. ... Mather, Karen A. (2018). A Meta-Analysis of Genome-Wide Association Studies of Growth Differentiation Factor-15 Concentration in Blood. Frontiers in Genetics, 9 (97), ARTN 97.10.3389/fgene.2018.00097.
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2018
Painter, Jodie N.; O'Mara, Tracy A.; Morris, Andrew P.; Cheng, Timothy H. T.; Gorman, Maggie; Martin, Lynn; Hodson, Shirley; Jones, Angela; Martin, Nicholas G.; Gordon, Scott; Henders, Anjali K.; Attia, John; McEvoy, Mark; Holliday, Elizabeth G.; Scott, Rodney J.; Webb, Penelope M.; Fasching, Peter A.; Beckmann, Matthias W.; Ekici, Arif B.; Hein, Alexander ... Spurdle, Amanda B. (2018). Genetic overlap between endometriosis and endometrial cancer: evidence from cross-disease genetic correlation and GWAS meta-analyses. Cancer Medicine, 7 (5), 1978−1987.10.1002/cam4.1445.
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Chen, Xu; Gustafsson, Stefan; Whitington, Thomas; Borne, Yan; Lorentzen, Erik; Sun, Jitong; Almgren, Peter; Su, Jun; Karlsson, Robert; Song, Jie; Lu, Yi; Zhan, Yiqiang; Hagg, Sara; Svensson, Per; Smedby, Karin E.; Slager, Susan L.; Ingelsson, Erik; Lindgren, Cecilia M.; Morris, Andrew P.; Melander, Olle ... Magnusson, Patrik K. E. (2018). A genome-wide association study of IgM antibody against phosphorylcholine: shared genetics and phenotypic relationship to chronic lymphocytic leukemia. Human Molecular Genetics, 27 (10), 1809−1818.10.1093/hmg/ddy094.
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2018
Malik, Rainer; Chauhan, Ganesh; Traylor, Matthew; Sargurupremraj, Muralidharan; Okada, Yukinori; Mishra, Aniket; Rutten-Jacobs, Loes; Giese, Anne-Katrin; van der Laan, Sander W.; Gretarsdottir, Solveig; Anderson, Christopher D.; Chong, Michael; Adams, Hieab H. H.; Ago, Tetsuro; Almgren, Peter; Amouyel, Philippe; Ay, Hakan; Bartz, Traci M.; Benavente, Oscar R.; Bevan, Steve ... Dichgans, Martin (2018). Multiancestry genome-wide association study of 520,000 subjects identifies 32 loci associated with stroke and stroke subtypes. Nature Genetics, 50 (4), 524−541.10.1038/s41588-018-0058-3.
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2018
Morris, A. P. (2018). Progress in defining the genetic contribution to type 2 diabetes susceptibility. Current Opinion in Genetics & Development, 50, 41−51.10.1016/j.gde.2018.02.003.
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2018
Jun, Goo; Manning, Alisa; Almeida, Marcio; Zawistowski, Matthew; Wood, Andrew R.; Teslovich, Tanya M.; Fuchsberger, Christian; Feng, Shuang; Cingolani, Pablo; Gaulton, Kyle J.; Dyer, Thomas; Blackwell, Thomas W.; Chen, Han; Chines, Peter S.; Choi, Sungkyoung; Churchhouse, Claire; Fontanillas, Pierre; King, Ryan; Lee, SungYoung; Lincoln, Stephen E. ... Blangero, John (2018). Evaluating the contribution of rare variants to type 2 diabetes and related traits using pedigrees. Proceedings of the National Academy of Sciences, 115 (2), 379−384.10.1073/pnas.1705859115.
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2018
Turcot, Valerie; Lu, Yingchang; Highland, Heather M.; Schurmann, Claudia; Justice, Anne E.; Fine, Rebecca S.; Bradfield, Jonathan P.; Esko, Tõnu; Giri, Ayush; Graff, Mariaelisa; Guo, Xiuqing; Hendricks, Audrey E.; Karaderi, Tugce; Lempradl, Adelheid; Locke, Adam E.; Mahajan, Anubha; Marouli, Eirini; Sivapalaratnam, Suthesh; Young, Kristin L.; Alfred, Tamuno ... Loos, Ruth J. F. (2018). Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity. Nature Genetics, 50 (1), 26−45. DOI: 10.1038/s41588-017-0011-x.
6.8.
2018
Flannick, Jason; Fuchsberger, Christian; Mahajan, Anubha; Teslovich, Tanya M; Agarwala, Vineeta; Gaulton, Kyle J; Caulkins, Lizz; Koesterer, Ryan; Ma, Clement; Moutsianas, Loukas; McCarthy, Davis J; Rivas, Manuel A; Perry, John R B; Sim, Xueling; Blackwell, Thomas W; Robertson, Neil R; Rayner, N William; Cingolani, Pablo; Locke, Adam E; Tajes, Juan Fernandez ... McCarthy, Mark I (2018). Erratum: Sequence data and association statistics from 12,940 type 2 diabetes cases and controls. Scientific Data, 5, 180002−180002. DOI: 10.1038/sdata.2018.2.
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Turcot, Valerie; Lu, Yingchang; Highland, Heather M.; Schurmann, Claudia; Justice, Anne E.; Fine, Rebecca S.; Bradfield, Jonathan P.; Esko, Tonu; Giri, Ayush; Graff, Mariaelisa; Guo, Xiuqing; Hendricks, Audrey E.; Karaderi, Tugce; Lempradl, Adelheid; Locke, Adam E.; Mahajan, Anubha; Marouli, Eirini; Sivapalaratnam, Suthesh; Young, Kristin L.; Alfred, Tamuno ... Loos, Ruth J. F. (2018). Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity (vol 50, pg 26, 2018). Nature Genetics, 50 (5), 766−767.10.1038/s41588-018-0082-3.
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2018
Evangelou, Evangelos; Warren, Helen R; Mosen-Ansorena, David; Mifsud, Borbala; Pazoki, Raha; Gao, He; Ntritsos, Georgios; Dimou, Niki; Cabrera, Claudia P; Karaman, Ibrahim; Ng, Fu Liang; Evangelou, Marina; Witkowska, Katarzyna; Tzanis, Evan; Hellwege, Jacklyn N; Giri, Ayush; Velez Edwards, Digna R; Sun, Yan V; Cho, Kelly; Gaziano, J Michael ... Caulfield, Mark J (2018). Publisher Correction: Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits. Nature Genetics, 50 (12), 1755−1755. DOI: 10.1038/s41588-018-0297-3.
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2017
Sánchez-Salguero, R.; Hevia, A.; Camarero, J. J.; Treydte, K.; Frank, D.; Crivellaro, A.; Domínguez-Delmás, M.; Hellman, L.; Kaczka, R.; Kaye, M.; Akhmetzyanov, L.; Ashiq, W.M.; Bhuyan, U.; Bondarenko, O.; Camisón, Á.; Camps, S.; García, V.C.; Vaz, F. C.; Gavrila, I. G.; Gulbranson, E. ... Volařík, D. (2017). An intensive tree-ring experience: Connecting education and research during the 25th European Dendroecological Fieldweek (Asturias, Spain). Dendrochronologia, 42, 80−93.10.1016/j.dendro.2016.12.005.
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2017
Lind, Lars; Ng, Esther; Ingelsson, Erik; Lindgren, Cecilia; Salihovic, Samira; van Bavel, Bert; Mahajan, Anubha; Lampa, Erik; Morris, Andrew P.; Lind, P. Monica (2017). Genetic and methylation variation in the CYP2B6 gene is related to circulating p,p '-dde levels in a population-based sample. Environment International, 212−218.10.1016/j.envint.2016.11.010.
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2017
Parra, Esteban J.; Mazurek, Andrew; Gignoux, Christopher R.; Sockell, Alexandra; Agostino, Michael; Morris, Andrew P.; Petty, Lauren E.; Hanis, Craig L.; Cox, Nancy J.; Valladares-Salgado, Adan; Below, Jennifer E.; Cruz, Miguel (2017). Admixture mapping in two Mexican samples identifies significant associations of locus ancestry with triglyceride levels in the BUD13/ZNF259/APOA5 region and fine mapping points to rs964184 as the main driver of the association signal. PLoS ONE, 2, ARTN e0172880. DOI: 10.1371/journal.pone.0172880.
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2017
Asimit, Jennifer L.; Payne, Felicity; Morris, Andrew P.; Cordell, Heather J.; Barroso, Ines (2017). A two-stage inter-rater approach for enrichment testing of variants associated with multiple traits. European Journal of Human Genetics, 3, 341−349.10.1038/ejhg.2016.171.
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2017
Wain, Louise V.; Shrine, Nick; Artigas, Maria Soler; Erzurumluoglu, A. Mesut; Noyvert, Boris; Bossini-Castillo, Lara; Obeidat, Ma'en; Henrys, Amanda P.; Portelli, Michael A.; Hall, Robert J.; Billington, Charlotte K.; Rimington, Tracy L.; Fenech, Anthony G.; John, Catherine; Blake, Tineka; Jackson, Victoria E.; Allen, Richard J.; Prins, Bram P.; Campbell, Archie; Porteous, David J. ... Tobin, Martin D. (2017). Genome-wide association analyses for lung function and chronic obstructive pulmonary disease identify new loci and potential druggable targets. Nature Genetics, 3, 416−425.10.1038/ng.3787.
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2017
Uimari, Outi; Rahmioglu, Nilufer; Nyholt, Dale R.; Vincent, Katy; Missmer, Stacey A.; Becker, Christian; Morris, Andrew P.; Montgomery, Grant W.; Zondervan, Krina T. (2017). Genome-wide genetic analyses highlight mitogen-activated protein kinase (MAPK) signaling in the pathogenesis of endometriosis. Human Reproduction, 4, 780−793.10.1093/humrep/dex024.
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2017
van Rooij, Frank J. A.; Qayyum, Rehan; Smith, Albert V.; Zhou, Yi; Trompet, Stella; Tanaka, Toshiko; Keller, Margaux F.; Chang, Li-Ching; Schmidt, Helena; Yang, Min-Lee; Chen, Ming-Huei; Hayes, James; Johnson, Andrew D.; Yanek, Lisa R.; Mueller, Christian; Lange, Leslie; Floyd, James S.; Ghanbari, Mohsen; Zonderman, Alan B.; Jukema, J. Wouter ... Ganesh, Santhi K. (2017). Genome-wide Trans-ethnic Meta-analysis Identifies Seven Genetic Loci Influencing Erythrocyte Traits and a Role for RBPMS in Erythropoiesis. The American Journal of Human Genetics, 1, 51−63.10.1016/j.ajhg.2016.11.016.
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2017
Cook, James P.; Mahajan, Anubha; Morris, Andrew P. (2017). Guidance for the utility of linear models in meta-analysis of genetic association studies of binary phenotypes. European Journal of Human Genetics, 2, 240−245.10.1038/ejhg.2016.150.
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2017
Kaakinen, Marika; Magi, Reedik; Fischer, Krista; Heikkinen, Jani; Jarvelin, Marjo-Riitta; Morris, Andrew P.; Prokopenko, Inga (2017). MARV: a tool for genome-wide multi-phenotype analysis of rare variants. BMC Bioinformatics, ARTN 110. DOI: 10.1186/s12859-017-1530-2.
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2017
Mägi, Reedik; Suleimanov, Yury V.; Clarke, Geraldine M.; Kaakinen, Marika; Fischer, Krista; Prokopenko, Inga; Morris, Andrew P. (2017). SCOPA and META-SCOPA: software for the analysis and aggregation of genome-wide association studies of multiple correlated phenotypes. BMC Bioinformatics, ARTN 25.10.1186/s12859-016-1437-3.
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2017
Manning, Alisa; Highland, Heather M.; Gasser, Jessica; Sim, Xueling; Tukiainen, Taru; Fontanillas, Pierre; Grarup, Niels; Rivas, Manuel A.; Mahajan, Anubha; Locke, Adam E.; Cingolani, Pablo; Pers, Tune H.; Vinuela, Ana; Brown, Andrew A.; Wu, Ying; Flannick, Jason; Fuchsberger, Christian; Gamazon, Eric R.; Gaulton, Kyle J.; Im, Hae Kyung ... Lindgren, Cecilia M. (2017). A Low-Frequency Inactivating AKT2 Variant Enriched in the Finnish Population Is Associated With Fasting Insulin Levels and Type 2 Diabetes Risk. Diabetes, 66 (7), 2019−2032. DOI: 10.2337/db16-1329.
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2017
Marshall, Christian R.; Marshall, Christian R.; Howrigan, Daniel P.; Merico, Daniele; Thiruvahindrapuram, Bhooma; Wu, Wenting; Greer, Douglas S.; Antaki, Danny; Shetty, Aniket; Holmans, Peter A.; Pinto, Dalila; Gujral, Madhusudan; Brandler, William M.; Malhotra, Dheeraj; Wang, Zhouzhi; Fajarado, Karin V. Fuentes; Maile, Michelle S.; Ripke, Stephan; Agartz, Ingrid; Albus, Margot ... Sebat, Jonathan (2017). Contribution of copy number variants to schizophrenia from a genome-wide study of 41,321 subjects. Nature Genetics, 1, 27−35. DOI: 10.1038/ng.3725.
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2017
Warren, Helen R.; Evangelou, Evangelos; Cabrera, Claudia P.; Gao, He; Ren, Meixia; Mifsud, Borbala; Ntalla, Ioanna; Surendran, Praveen; Liu, Chunyu; Cook, James P.; Kraja, Aldi T.; Drenos, Fotios; Loh, Marie; Verweij, Niek; Marten, Jonathan; Karaman, Ibrahim; Lepe, Marcelo P. Segura; O'Reilly, Paul F.; Knight, Joanne; Snieder, Harold ... Ehret, Georg B. (2017). Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk. Nature Genetics, 3, 403−415. DOI: 10.1038/ng.3768.
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2017
Justice, Anne E.; Winkler, Thomas W.; Feitosa, Mary F.; Graff, Misa; Fisher, Virginia A.; Young, Kristin; Barata, Llilda; Deng, Xuan; Czajkowski, Jacek; Hadley, David; Ngwa, Julius S.; Ahluwalia, Tarunveer S.; Chu, Audrey Y.; Heard-Costa, Nancy L.; Lim, Elise; Perez, Jeremiah; Eicher, John D.; Kutalik, Zoltan; Xue, Luting; Mahajan, Anubha ... Cupples, L. Adrienne (2017). Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits. Nature Communications, 8 (14977), ARTN 14977. DOI: 10.1038/ncomms14977.
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2017
Mitt, Mario; Kals, Mart; Parn, Kalle; Gabriel, Stacey B; Lander, Eric S; Palotie, Aarno; Ripatti, Samuli; Morris, Andrew P; Metspalu, Andres; Esko, Tonu; Magi, Reedik; Palta, Priit; (2017). Improved imputation accuracy of rare and low-frequency variants using population-specific high-coverage WGS-based imputation reference panel. European Journal of Human Genetics, 25 (7), 869−879. DOI: 10.1038/ejhg.2017.51.
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2017
Wain, Louise V.; Vaez, Ahmad; Jansen, Rick; Joehanes, Roby; van der Most, Peter J.; Erzurumluoglu, A. Mesut; O'Reilly, Paul F.; Cabrera, Claudia P.; Warren, Helen R.; Rose, Lynda M.; Verwoert, Germaine C.; Hottenga, Jouke-Jan; Strawbridge, Rona J.; Esko, Tõnu; Arking, Dan E.; Hwang, Shih-Jen; Guo, Xiuqing; Kutalik, Zoltan; Trompet, Stella; Shrine, Nick ... Xiao, Limin (2017). Novel Blood Pressure Locus and Gene Discovery Using Genome-Wide Association Study and Expression Data Sets From Blood and the Kidney. Hypertension, 70 (3), e4−e19. DOI: 10.1161/HYPERTENSIONAHA.117.09438.
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2017
Shungin, Dmitry; Deng, Wei Q.; Varga, Tibor V.; Luan, Jian'an; Mihailov, Evelin; Metspalu, Andres; Morris, Andrew P.; Forouhi, Nita G.; Lindgren, Cecilia; Magnusson, Patrik K. E.; Pedersen, Nancy L.; Hallmans, Goran; Chu, Audrey Y.; Justice, Anne E.; Graff, Mariaelisa; Winkler, Thomas W.; Rose, Lynda M.; Langenberg, Claudia; Cupples, L. Adrienne; Ridker, Paul M. ... Franks, Paul W. (2017). Ranking and characterization of established BMI and lipid associated loci as candidates for gene-environment interactions. PLoS Genetics, 13 (6), e1006812. DOI: 10.1371/journal.pgen.1006812.
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Marouli, Eirini; Graff, Mariaelisa; Medina-Gomez, Carolina; Lo, Ken Sin; Wood, Andrew R.; Kjaer, Troels R.; Fine, Rebecca S.; Lu, Yingchang; Schurmann, Claudia; Highland, Heather M.; Rueger, Sina; Thorleifsson, Gudmar; Justice, Anne E.; Lamparter, David; Stirrups, Kathleen E.; Turcot, Valerie; Young, Kristin L.; Winkler, Thomas W.; Esko, Tonu; Karaderi, Tugce ... Lettre, Guillaume (2017). Rare and low-frequency coding variants alter human adult height. Nature, 7640, 186−190. DOI: 10.1038/nature21039.
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Webb, Thomas R.; Erdmann, Jeanette; Stirrups, Kathleen E.; Stitziel, Nathan O.; Masca, Nicholas G. D.; Jansen, Henning; Kanoni, Stavroula; Nelson, Christopher P.; Ferrario, Paola G.; Koenig, Inke R.; Eicher, John D.; Johnson, Andrew D.; Hamby, Stephen E.; Betsholtz, Christer; Ruusalepp, Arno; Franzen, Oscar; Schadt, Eric E.; Bjoerkegren, Johan L. M.; Weeke, Peter E.; Auer, Paul L. ... Kathiresan, Sekar (2017). Systematic Evaluation of Pleiotropy Identifies 6 Further Loci Associated With Coronary Artery Disease. Journal of the American College of Cardiology, 7, 823−836. DOI: 10.1016/j.jacc.2016.11.056.
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Rahmioglu, Nilufer; Drong, Alexander W; Lockstone, Helen; Tapmeier, Thomas; Hellner, Karin; Saare, Merli; Laisk-Podar, Triin; Dew, Christine; Tough, Emily; Nicholson, George; Peters, Maire; Morris, Andrew P; Lindgren, Cecilia M; Becker, Christian M; Zondervan, Krina T (2017). Variability of genome-wide DNA methylation and mRNA expression profiles in reproductive and endocrine disease related tissues. Epigenetics, 12 (10), 897−908. DOI: 10.1080/15592294.2017.1367475.
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Below, Jennifer E.; Parra, Esteban J.; Gamazon, Eric R.; Torres, Jason; Krithika, S.; Candille, Sophie; Lu, Yingchang; Manichakul, Ani; Peralta-Romero, Jesus; Duan, Qing; Li, Yun; Morris, Andrew P.; Gottesman, Omri; Bottinger, Erwin; Wang, Xin-Qun; Taylor, Kent D.; Chen, Y. -D. Ida; Rotter, Jerome I.; Rich, Stephen S.; Loos, Ruth J. F. ... Valladares-Salgado, Adan (2017). Meta-analysis of lipid-traits in Hispanics identifies novel loci, population-specific effects, and tissue-specific enrichment of eQTLs. Scientific Reports, 6 (19429), 1−13.10.1038/srep19429.
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2017
Kaakinen, Marika; Magi, Reedik; Fischer, Krista; Heikkinen, Jani; Jarvelin, Marjo-Riitta; Morris, Andrew P.; Prokopenko, Inga (2017). A rare-variant test for high-dimensional data. European Journal of Human Genetics, 25 (8), 988−994.10.1038/ejhg.2017.90.
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2017
Flannick, Jason; Fuchsberger, Christian; Mahajan, Anubha; Teslovich, Tanya M.; Agarwala, Vineeta; Gaulton, Kyle J.; Caulkins, Lizz; Koesterer, Ryan; Ma, Clement; Moutsianas, Loukas; McCarthy, Davis J.; Rivas, Manuel A.; Perry, John R. B.; Sim, Xueling; Blackwell, Thomas W.; Robertson, Neil R.; Rayner, N. William; Cingolani, Pablo; Locke, Adam E.; Tajes, Juan Fernandez ... McCarthy, Mark I. (2017). Data Descriptor: Sequence data and association statistics from 12,940 type 2 diabetes cases and controls. Scientific Data, 4, ARTN 170179. DOI: 10.1038/sdata.2017.179.
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2017
Liu, Dajiang J.; Peloso, Gina M.; Yu, Haojie; Butterworth, Adam S.; Wang, Xiao; Mahajan, Anubha; Saleheen, Danish; Emdin, Connor; Alam, Dewan; Alves, Alexessander Couto; Amouyel, Philippe; Di Angelantonio, Emanuele; Arveiler, Dominique; Assimes, Themistocles L.; Auer, Paul L.; Baber, Usman; Ballantyne, Christie M.; Bang, Lia E.; Benn, Marianne; Bis, Joshua C. ... Kathiresan, Sekar (2017). Exome-wide association study of plasma lipids in > 300,000 individuals. Nature Genetics, 49 (12), 1758−1772. DOI: 10.1038/ng.3977.
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Strawbridge, Rona J; Silveira, Angela; Hoed, Marcel den; Gustafsson, Stefan; Luan, Jian'an; Rybin, Denis; Dupuis, Josée; Li-Gao, Ruifang; Kavousi, Maryam; Dehghan, Abbas; Haljas, Kadri; Lahti, Jari; Gådin, Jesper R; Bäcklund, Alexandra; de Faire, Ulf; Gertow, Karl; Giral, Phillipe; Goel, Anuj; Humphries, Steve E; Kurl, Sudhir ... , (2017). Identification of a novel proinsulin-associated SNP and demonstration that proinsulin is unlikely to be a causal factor in subclinical vascular remodelling using Mendelian randomisation. Atherosclerosis, 266, 196−204.10.1016/j.atherosclerosis.2017.09.031.
1.1.
2017
Kraja, Aldi T.; Cook, James P.; Warren, Helen R.; Surendran, Praveen; Liu, Chunyu; Evangelou, Evangelos; Manning, Alisa K.; Grarup, Niels; Drenos, Fotios; Sim, Xueling; Smith, Albert Vernon; Amin, Najaf; Blakemore, Alexandra I. F.; Bork-Jensen, Jette; Brandslund, Ivan; Farmaki, Aliki-Eleni; Fava, Cristiano; Ferreira, Teresa; Herzig, Karl-Heinz; Giri, Ayush ... Howson, Joanna M. M. (2017). New Blood Pressure-Associated Loci Identified in Meta-Analyses of 475000 Individuals. Circulation Cardiovascular Genetics, 10 (5), UNSP e001778.10.1161/CIRCGENETICS.117.001778.
1.1.
2017
Mägi, R; Horikoshi, M; Sofer, T; Mahajan, A; Kitajima, H; Franceschini, N; McCarthy, MI; COGENT-Kidney, Consortium; T2D-GENES, Consortium; Morris, AP (2017). Trans-ethnic meta-regression of genome-wide association studies accounting for ancestry increases power for discovery and improves fine-mapping resolution. Human Molecular Genetics, 26 (18), 3639−3650.10.1093/hmg/ddx280.
1.1.
2017
Flannick J, Fuchsberger C, Mahajan A, Teslovich TM, Agarwala V, Gaulton KJ, Caulkins L, Koesterer R, Ma C, Moutsianas L, McCarthy DJ, Rivas MA, Perry JRB, Sim X, Blackwell TW, Robertson NR, Rayner NW, Cingolani P, Locke AE, Tajes JF, Highland HM, Dupuis J, Chines PS, Lindgren CM, Hartl C, Jackson AU, Chen H, Huyghe JR, van de Bunt M, Pearson RD, Kumar A, Müller-Nurasyid M, Grarup N, Stringham HM, Gamazon ER, Lee J, Chen Y, Scott RA, Below JE, Chen P, Huang J, Go MJ, Stitzel ML, Pasko D, Parker SCJ, Varga TV, Green T, Beer NL, Day-Williams AG, Ferreira T, Fingerlin T, Horikoshi M, Hu C, Huh I, Ikram MK, Kim BJ, Kim Y, Kim YJ, Kwon MS, Lee J, Lee S, Lin KH, Maxwell TJ, Nagai Y, Wang X, Welch RP, Yoon J, Zhang W, Barzilai N, Voight BF, Han BG, Jenkinson CP, Kuulasmaa T, Kuusisto J, Manning A, Ng MCY, Palmer ND, Balkau B, Stančáková A, Abboud HE, Boeing H, Giedraitis V, Prabhakaran D, Gottesman O, Scott J, Carey J, Kwan P, Grant G, Smith JD, Neale BM, Purcell S, Butterworth AS, Howson JMM, Lee HM, Lu Y, Kwak SH, Zhao W, Danesh J, Lam VKL, Park KS, Saleheen D, So WY, Tam CHT, Afzal U, Aguilar D, Arya R, Aung T, Chan E, Navarro C, Cheng CY, Palli D, Correa A, Curran JE, Rybin D, Farook VS, Fowler SP, Freedman BI, Griswold M, Hale DE, Hicks PJ, Khor CC, Kumar S, Lehne B, Thuillier D, Lim WY, Liu J, Loh M, Musani SK, Puppala S, Scott WR, Yengo L, Tan ST, Taylor HA, Thameem F, Wilson G, Wong TY, Njølstad PR, Levy JC, Mangino M, Bonnycastle LL, Schwarzmayr T, Fadista J, Surdulescu GL, Herder C, Groves CJ, Wieland T, Bork-Jensen J, Brandslund I, Christensen C, Koistinen HA, Doney ASF, Kinnunen L, Esko T, Farmer AJ, Hakaste L, Hodgkiss D, Kravic J, Lyssenko V, Hollensted M, Jørgensen ME, Jørgensen T, Ladenvall C, Justesen JM, Käräjämäki A, Kriebel J, Rathmann W, Lannfelt L, Lauritzen T, Narisu N, Linneberg A, Melander O, Milani L, Neville M, Orho-Melander M, Qi L, Qi Q, Roden M, Rolandsson O, Swift A, Rosengren AH, Stirrups K, Wood AR, Mihailov E, Blancher C, Carneiro MO, Maguire J, Poplin R, Shakir K, Fennell T, DePristo M, de Angelis MH, Deloukas P, Gjesing AP, Jun G, Nilsson P, Murphy J, Onofrio R, Thorand B, Hansen T, Meisinger C, Hu FB, Isomaa B, Karpe F, Liang L, Peters A, Huth C, O'Rahilly SP, Palmer CNA, Pedersen O, Rauramaa R, Tuomilehto J, Salomaa V, Watanabe RM, Syvänen AC, Bergman RN, Bharadwaj D, Bottinger EP, Cho YS, Chandak GR, Chan JC, Chia KS, Daly MJ, Ebrahim SB, Langenberg C, Elliott P, Jablonski KA, Lehman DM, Jia W, Ma RCW, Pollin TI, Sandhu M, Tandon N, Froguel P, Barroso I, Teo YY, Zeggini E, Loos RJF, Small KS, Ried JS, DeFronzo RA, Grallert H, Glaser B, Metspalu A, Wareham NJ, Walker M, Banks E, Gieger C, Ingelsson E, Im HK, Illig T, Franks PW, Buck G, Trakalo J, Buck D, Prokopenko I, Mägi R, Lind L, Farjoun Y, Owen KR, Gloyn AL, Strauch K, Tuomi T, Kooner JS, Lee JY, Park T, Donnelly P, Morris AD, Hattersley AT, Bowden DW, Collins FS, Atzmon G, Chambers JC, Spector TD, Laakso M, Strom TM, Bell GI, Blangero J, Duggirala R, Tai ES, McVean G, Hanis CL, Wilson JG, Seielstad M, Frayling TM, Meigs JB, Cox NJ, Sladek R, Lander ES, Gabriel S, Mohlke KL, Meitinger T, Groop L, Abecasis G, Scott LJ, Morris AP, Kang HM, Altshuler D, Burtt NP, Florez JC, Boehnke M, McCarthy MI. (2017). Sequence data and association statistics from 12,940 type 2 diabetes cases and controls. Scientific Data, 4, 170179. DOI: 10.1038/sdata.2017.179.
1.1.
2017
Sapkota, Yadav; De Vivo, Immaculata; Steinthorsdottir, Valgerdur; Fassbender, Amelie; Bowdler, Lisa; Buring, Julie E.; Edwards, Todd L.; Jones, Sarah; Dorien, O.; Peterse, Danielle; Rexrode, Kathryn M.; Ridker, Paul M.; Schork, Andrew J.; Thorleifsson, Gudmar; Wallace, Leanne M.; Kraft, Peter; Morris, Andrew P.; Nyholt, Dale R.; Edwards, Digna R. Velez; Nyegaard, Mette ... Montgomery, Grant W. (2017). Analysis of potential protein-modifying variants in 9000 endometriosis patients and 150000 controls of European ancestry. Scientific Reports, 7, ARTN 11380.10.1038/s41598-017-10440-9.
1.1.
2017
Wheeler, Eleanor; Leong, Aaron; Liu, Ching-Ti; Hivert, Marie-France; Strawbridge, Rona J.; Podmore, Clara; Li, Man; Yao, Jie; Sim, Xueling; Hong, Jaeyoung; Chu, Audrey Y.; Zhang, Weihua; Wang, Xu; Chen, Peng; Maruthur, Nisa M.; Porneala, Bianca C.; Sharp, Stephen J.; Jia, Yucheng; Kabagambe, Edmond K.; Chang, Li-Ching ... Meigs, James B. (2017). Impact of common genetic determinants of Hemoglobin A1c on type 2 diabetes risk and diagnosis in ancestrally diverse populations: A transethnic genome-wide meta-analysis. PLoS Medicine, 14 (9), ARTN e1002383.10.1371/journal.pmed.1002383.
1.1.
2017
Nolte, Ilja M.; Munoz, M. Loretto; Tragante, Vinicius; Amare, Azmeraw T.; Jansen, Rick; Vaez, Ahmad; von der Heyde, Benedikt; Avery, Christy L.; Bis, Joshua C.; Dierckx, Bram; van Dongen, Jenny; Gogarten, Stephanie M.; Goyette, Philippe; Hernesniemi, Jussi; Huikari, Ville; Hwang, Shih-Jen; Jaju, Deepali; Kerr, Kathleen F.; Kluttig, Alexander; Krijthe, Bouwe P. ... de Geus, Eco J. C. (2017). Genetic loci associated with heart rate variability and their effects on cardiac disease risk. Nature Communications, 8, ARTN 15805.10.1038/ncomms15805.
1.1.
2017
Windholz, Jan; Kovacs, Peter; Schlicke, Marina; Franke, Christin; Mahajan, Anubha; Morris, Andrew P.; Lemke, Johannes R.; Klammt, Juergen; Kiess, Wieland; Schoeneberg, Torsten; Paeffle, Roland; Koerner, Antje (2017). Copy number variations in "classical" obesity candidate genes are not frequently associated with severe early-onset obesity in children. Journal of Pediatric Endocrinology and Metabolism, 30 (5), 507−515.10.1515/jpem-2016-0435.
1.1.
2017
Scott, Robert A.; Scott, Laura J.; Maegi, Reedik; Marullo, Letizia; Gaulton, Kyle J.; Kaakinen, Marika; Pervjakova, Natalia; Pers, Tune H.; Johnson, Andrew D.; Eicher, John D.; Jackson, Anne U.; Ferreira, Teresa; Lee, Yeji; Ma, Clement; Steinthorsdottir, Valgerdur; Thorleifsson, Gudmar; Qi, Lu; Van Zuydam, Natalie R.; Mahajan, Anubha; Chen, Han ... Prokopenko, Inga (2017). An Expanded Genome-Wide Association Study of Type 2 Diabetes in Europeans. Diabetes, 66 (11), 2888−2902. DOI: 10.2337/db16-1253.
1.1.
2017
Tachmazidou, Ioanna; Suveges, Daniel; Min, Josine L.; Ritchie, Graham R. S.; Steinberg, Julia; Walter, Klaudia; Iotchkova, Valentina; Schwartzentruber, Jeremy; Huang, Jie; Memari, Yasin; McCarthy, Shane; Crawford, Andrew A.; Bombieri, Cristina; Cocca, Massimiliano; Farmaki, Aliki-Eleni; Gaunt, Tom R.; Jousilahti, Pekka; Kooijman, Marjolein N.; Lehne, Benjamin; Malerba, Giovanni ... Zeggini, Eleftheria (2017). Whole-Genome Sequencing Coupled to Imputation Discovers Genetic Signals for Anthropometric Traits. The American Journal of Human Genetics, 100 (6), 865−884.10.1016/j.ajhg.2017.04.014.
1.1.
2017
Sapkota, Yadav; Steinthorsdottir, Valgerdur; Morris, Andrew P.; Fassbender, Amelie; Rahmioglu, Nilufer; De Vivo, Immaculata; Buring, Julie E.; Zhang, Futao; Edwards, Todd L.; Jones, Sarah; Dorien, O.; Peterse, Danielle; Rexrode, Kathryn M.; Ridker, Paul M.; Schork, Andrew J.; MacGregor, Stuart; Martin, Nicholas G.; Becker, Christian M.; Adachi, Sosuke; Yoshihara, Kosuke ... Nyholt, Dale R. (2017). Meta-analysis identifies five novel loci associated with endometriosis highlighting key genes involved in hormone metabolism. Nature Communications, 8, ARTN 15539.10.1038/ncomms15539.
1.1.
2017
Syed, Hamzah; Jorgensen, Andrea L.; Morris, Andrew P. (2017). SurvivalGWAS_SV: software for the analysis of genome-wide association studies of imputed genotypes with "time-to-event" outcomes. BMC Bioinformatics, 18, ARTN 265.10.1186/s12859-017-1683-z.
1.1.
2017
Christophersen, Ingrid E.; Rienstra, Michiel; Roselli, Carolina; Yin, Xiaoyan; Geelhoed, Bastiaan; Barnard, John; Lin, Honghuang; Arking, Dan E.; Smith, Albert V.; Albert, Christine M.; Chaffin, Mark; Tucker, Nathan R.; Li, Molong; Klarin, Derek; Bihlmeyer, Nathan A.; Low, Siew-Kee; Weeke, Peter E.; Mueller-Nurasyid, Martina; Smith, J. Gustav; Brody, Jennifer A. ... Ellinor, Patrick T. (2017). Large-scale analyses of common and rare variants identify 12 new loci associated with atrial fibrillation. Nature Genetics, 49 (6), 946−956.10.1038/ng.3843.
1.1.
2017
Wild, Philipp S.; Felix, Janine F.; Schillert, Arne; Teumer, Alexander; Chen, Ming-Huei; Leening, Maarten J. G.; Voelker, Uwe; Grossmann, Vera; Brody, Jennifer A.; Irvin, Marguerite R.; Shah, Sanjiv J.; Pramana, Setia; Lieb, Wolfgang; Schmidt, Reinhold; Stanton, Alice V.; Malzahn, Doerthe; Smith, Albert Vernon; Sundstrom, Johan; Minelli, Cosetta; Ruggiero, Daniela ... Doerr, Marcus (2017). Large-scale genome-wide analysis identifies genetic variants associated with cardiac structure and function. Journal of Clinical Investigation, 127 (5), 1798−1812.10.1172/JCI84840.
1.1.
2017
Turner, Richard M.; Yin, Peng; Hanson, Anita; FitzGerald, Richard; Morris, Andrew P.; Stables, Rod H.; Jorgensen, Andrea L.; Pirmohamed, Munir (2017). Investigating the prevalence, predictors, and prognosis of suboptimal statin use early after a non-ST elevation acute coronary syndrome. Journal of Clinical Lipidology, 11 (1), 204−214.10.1016/j.jacl.2016.12.007.
1.1.
2017
Folkersen, Lasse; Fauman, Eric; Sabater-Lleal, Maria; Strawbridge, Rona J.; Franberg, Mattias; Sennblad, Bengt; Baldassarre, Damiano; Veglia, Fabrizio; Humphries, Steve E.; Rauramaa, Rainer; de Faire, Ulf; Smit, Andries J.; Giral, Philippe; Kurl, Sudhir; Mannarino, Elmo; Enroth, Stefan; Johansson, Asa; Enroth, Sofia Bosdotter; Gustafsson, Stefan; Lind, Lars ... Malarstig, Anders (2017). Mapping of 79 loci for 83 plasma protein biomarkers in cardiovascular disease. PLoS Genetics, 13 (4), ARTN e1006706.10.1371/journal.pgen.1006706.
1.1.
2017
Hu, Yao; Tanaka, Toshiko; Zhu, Jingwen; Guan, Weihua; Wu, Jason H. Y.; Psaty, Bruce M.; McKnight, Barbara; King, Irena B.; Sun, Qi; Richard, Melissa; Manichaikul, Ani; Frazier-Wood, Alexis C.; Kabagambe, Edmond K.; Hopkins, Paul N.; Ordovas, Jose M.; Ferrucci, Luigi; Bandinelli, Stefania; Arnett, Donna K.; Chen, Yii-Der I.; Liang, Shuang ... Lin, Xu (2017). Discovery and fine-mapping of loci associated with MUFAs through trans-ethnic meta-analysis in Chinese and European populations. The Journal of Lipid Research, 58 (5), 974−981.10.1194/jlr.P071860.
1.1.
2017
Carr, Daniel F.; Bourgeois, Stephane; Chaponda, Mas; Takeshita, Louise Y.; Morris, Andrew P.; Castro, Elena M. Cornejo; Alfirevic, Ana; Jones, Andrew R.; Rigden, Daniel J.; Haldenby, Sam; Khoo, Saye; Lalloo, David G.; Heyderman, Robert S.; Dandara, Collet; Kampira, Elizabeth; van Oosterhout, Joep J.; Ssali, Francis; Munderi, Paula; Novelli, Giuseppe; Borgiani, Paola ... Pirmohamed, Munir (2017). Genome-wide association study of nevirapine hypersensitivity in a sub-Saharan African HIV-infected population. Journal of Antimicrobial Chemotherapy, 72 (4), 1152−1162. DOI: 10.1093/jac/dkw545.
1.1.
2017
Zillikens, M. Carola; Demissie, Serkalem; Hsu, Yi-Hsiang; Yerges-Armstrong, Laura M.; Chou, Wen-Chi; Stolk, Lisette; Livshits, Gregory; Broer, Linda; Johnson, Toby; Koller, Daniel L.; Kutalik, Zoltyn; Luan, Jian'an; Malkin, Ida; Ried, Janina S.; Smith, Albert V.; Thorleifsson, Gudmar; Vandenput, Liesbeth; Zhao, Jing Hua; Zhang, Weihua; Aghdassi, Ali ... Kiel, Douglas P. (2017). Large meta-analysis of genome-wide association studies identifies five loci for lean body mass. Nature Communications, 8, ARTN 80.10.1038/s41467-017-00031-7.
5.1.
2017
Rahmioglu, Nilufer; Lockstone, Helen; Ferreira, Teresa; Magi, Reedik; Van De Bunt, Martijn; Lindgren, Cecilia; Morris, Andrew; Becker, Christian; Zondervan, Krina (2017). Large-Scale Integrated Genome-Wide RNA Sequencing, miRNA Array, and Genomic Analyses to Unravel the Functionality of Genome-Wide Association Results in Endometriosis. Reproductive Sciences, 24, 205A−206A.
5.1.
2017
Kaakinen, Marika; Magi, Reedik; Lagou, Vasiliki; Claringbould, Annique; Gaulton, Kyle; Fischer, Krista; Morris, Andrew; Prokopenko, Inga (2017). Multi-Phenotype Genome-Wide Meta-Analysis of Lipid Levels and BMI in 64,736 Europeans Suggests Shared Genetic Architecture. Genetic Epidemiology, 41 (7), 652−653.
1.1.
2016
Fuchsberger, Christian; Flannick, Jason; Teslovich, Tanya M; Mahajan, Anubha; Agarwala, Vineeta; Gaulton, Kyle J; Ma, Clement; Fontanillas, Pierre; Moutsianas, Loukas; McCarthy, Davis J; Rivas, Manuel A; Perry, John R B; Sim, Xueling; Blackwell, Thomas W; Robertson, Neil R; Rayner, N William; Cingolani, Pablo; Locke, Adam E; Tajes, Juan Fernandez; Highland, Heather M ... McCarthy, Mark I (2016). The genetic architecture of type 2 diabetes. Nature, 536 (7614), 41−47. DOI: 10.1038/nature18642.
1.1.
2016
Lessard, Samuel; Manning, Alisa K; Low-Kam, Cécile; Auer, Paul L; Giri, Ayush; Graff, Mariaelisa; Schurmann, Claudia; Yaghootkar, Hanieh; Luan, Jian'an; Esko, Tonu; Karaderi, Tugce; Bottinger, Erwin P; Lu, Yingchang; Carlson, Chris; Caulfield, Mark; Dubé, Marie-Pierre; Jackson, Rebecca D; Kooperberg, Charles; McKnight, Barbara; Mongrain, Ian ... Lettre, Guillaume (2016). Testing the role of predicted gene knockouts in human anthropometric trait variation. Human Molecular Genetics, 25 (10), 1−11. DOI: 10.1093/hmg/ddw055.
1.1.
2016
Pattaro, Cristian; Teumer, Alexander; Gorski, Mathias; Chu, Audrey Y; Li, Man; Mijatovic, Vladan; Garnaas, Maija; Tin, Adrienne; Sorice, Rossella; Li, Yong; Taliun, Daniel; Olden, Matthias; Foster, Meredith; Yang, Qiong; Chen, Ming-Huei; Pers, Tune H; Johnson, Andrew D; Ko, Yi-An; Fuchsberger, Christian; Tayo, Bamidele ... Fox, Caroline S (2016). Genetic associations at 53 loci highlight cell types and biological pathways relevant for kidney function. Nature Communications, 7 (10023), 10023−10023. DOI: 10.1038/ncomms10023.
1.1.
2016
Pervjakova, Natalia; Kasela, Silva; Morris, Andrew P; Kals, Mart; Metspalu, Andres; Lindgren, Cecilia M; Salumets, Andres; Mägi, Reedik (2016). Imprinted genes and imprinting control regions show predominant intermediate methylation in adult somatic tissues. Epigenomics, 8 (6), 789−799. DOI: 10.2217/epi.16.8.
1.1.
2016
Lu, Yingchang; Day, Felix R; Gustafsson, Stefan; Buchkovich, Martin L; Na, Jianbo; Bataille, Veronique; Cousminer, Diana L; Dastani, Zari; Drong, Alexander W; Esko, Tõnu; Evans, David M; Falchi, Mario; Feitosa, Mary F; Ferreira, Teresa; Hedman, Åsa K; Haring, Robin; Hysi, Pirro G; Iles, Mark M; Justice, Anne E; Kanoni, Stavroula ... Loos, Ruth J F (2016). New loci for body fat percentage reveal link between adiposity and cardiometabolic disease risk. Nature Communications, 7, 10495−10495.10.1038/ncomms10495.
1.1.
2016
Ehret, Georg B; Ferreira, Teresa; Chasman, Daniel I; Jackson, Anne U; Schmidt, Ellen M; Johnson, Toby; Thorleifsson, Gudmar; Luan, Jian'an; Donnelly, Louise A; Kanoni, Stavroula; Petersen, Ann-Kristin; Pihur, Vasyl; Strawbridge, Rona J; Shungin, Dmitry; Hughes, Maria F; Meirelles, Osorio; Kaakinen, Marika; Bouatia-Naji, Nabila; Kristiansson, Kati; Shah, Sonia ... Munroe, Patricia B. (2016). The genetics of blood pressure regulation and its target organs from association studies in 342,415 individuals. Nature Genetics, 48 (10), 1171−1184. DOI: 10.1038/ng.3667.
1.1.
2016
Läll, Kristi; Mägi, Reedik; Morris, Andrew; Metspalu, Andres; Fischer, Krista (2016). Personalized risk prediction for type 2 diabetes: the potential of genetic risk scores. Genetics in Medicine, 1−10. DOI: 10.1038/gim.2016.103.
1.1.
2016
Scott, Robert A.; Freitag, Daniel F.; Li, Li; Chu, Audrey Y.; Surendran, Praveen; Young, Robin; Grarup, Niels; Stancakova, Alena; Chen, Yuning; Varga, Tibor V.; Yaghootkar, Hanieh; Luan, Jian'an; Zhao, Jing Hua; Willems, Sara M.; Wessel, Jennifer; Wang, Shuai; Maruthur, Nisa; Michailidou, Kyriaki; Pirie, Ailith; van der Lee, Sven J. ... Waterworth, Dawn M. (2016). A genomic approach to therapeutic target validation identifies a glucose-lowering GLP1R variant protective for coronary heart disease. Science Translational Medicine, 341, ARTN 341ra76.10.1126/scitranslmed.aad3744.
1.1.
2016
Ried JS, Jeff M J, Chu AY, Bragg-Gresham JL, van Dongen J, Huffman JE, Ahluwalia TS, Cadby G, Eklund N, Eriksson J, Esko T, Feitosa MF, Goel A, Gorski M, Hayward C, Heard-Costa NL, Jackson AU, Jokinen E, Kanoni S, Kristiansson K, Kutalik Z, Lahti J, Luan J, Mägi R, Mahajan A, Mangino M, Medina-Gomez C, Monda KL, Nolte IM, Pérusse L, Prokopenko I, Qi L, Rose LM, Salvi E, Smith MT, Snieder H, Stančáková A, Ju Sung Y, Tachmazidou I, Teumer A, Thorleifsson G, van der Harst P, Walker RW, Wang SR, Wild SH, Willems SM, Wong A, Zhang W, Albrecht E, Couto Alves A, Bakker SJ, Barlassina C, Bartz TM, Beilby J, Bellis C, Bergman RN, Bergmann S, Blangero J, Blüher M, Boerwinkle E, Bonnycastle LL, Bornstein SR, Bruinenberg M, Campbell H, Chen YI, Chiang CW, Chines PS, Collins FS, Cucca F, Cupples LA, D'Avila F, de Geus EJ, Dedoussis G, Dimitriou M, Döring A, Eriksson JG, Farmaki AE, Farrall M, Ferreira T, Fischer K, Forouhi NG, Friedrich N, Gjesing AP, Glorioso N, Graff M, Grallert H, Grarup N, Gräßler J, Grewal J, Hamsten A, Harder MN, Hartman CA, Hassinen M, Hastie N, Hattersley AT, Havulinna AS, Heliövaara M, Hillege H, Hofman A, Holmen O, Homuth G, Hottenga JJ, Hui J, Husemoen LL, Hysi PG, Isaacs A, Ittermann T, Jalilzadeh S, James AL, Jørgensen T, Jousilahti P, Jula A, Marie Justesen J, Justice AE, Kähönen M, Karaleftheri M, Tee Khaw K, Keinanen-Kiukaanniemi SM, Kinnunen L, Knekt PB, Koistinen HA, Kolcic I, Kooner IK, Koskinen S, Kovacs P, Kyriakou T, Laitinen T, Langenberg C, Lewin AM, Lichtner P, Lindgren CM, Lindström J, Linneberg A, Lorbeer R, Lorentzon M, Luben R, Lyssenko V, Männistö S, Manunta P, Leach IM, McArdle WL, Mcknight B, Mohlke KL, Mihailov E, Milani L, Mills R, Montasser ME, Morris AP, Müller G, Musk AW, Narisu N, Ong KK, Oostra BA, Osmond C, Palotie A, Pankow JS, Paternoster L, Penninx BW, Pichler I, Pilia MG, Polašek O, Pramstaller PP, Raitakari OT, Rankinen T, Rao DC, Rayner NW, Ribel-Madsen R, Rice TK, Richards M, Ridker PM, Rivadeneira F, Ryan KA, Sanna S, Sarzynski MA, Scholtens S, Scott RA, Sebert S, Southam L, Sparsø TH, Steinthorsdottir V, Stirrups K, Stolk RP, Strauch K, Stringham HM, Swertz MA, Swift AJ, Tönjes A, Tsafantakis E, van der Most PJ, Van Vliet-Ostaptchouk JV, Vandenput L, Vartiainen E, Venturini C, Verweij N, Viikari JS, Vitart V, Vohl MC, Vonk JM, Waeber G, Widén E, Willemsen G, Wilsgaard T, Winkler TW, Wright AF, Yerges-Armstrong LM, Hua Zhao J, Carola Zillikens M, Boomsma DI, Bouchard C, Chambers JC, Chasman DI, Cusi D, Gansevoort RT, Gieger C, Hansen T, Hicks AA, Hu F, Hveem K, Jarvelin MR, Kajantie E, Kooner JS, Kuh D, Kuusisto J, Laakso M, Lakka TA, Lehtimäki T, Metspalu A, Njølstad I, Ohlsson C, Oldehinkel AJ, Palmer LJ, Pedersen O, Perola M, Peters A, Psaty BM, Puolijoki H, Rauramaa R, Rudan I, Salomaa V, Schwarz PE, Shudiner AR, Smit JH, Sørensen TI, Spector TD, Stefansson K, Stumvoll M, Tremblay A, Tuomilehto J, Uitterlinden AG, Uusitupa M, Völker U, Vollenweider P, Wareham NJ, Watkins H, Wilson JF, Zeggini E, Abecasis GR, Boehnke M, Borecki IB, Deloukas P, van Duijn CM, Fox C, Groop LC, Heid IM, Hunter DJ, Kaplan RC, McCarthy MI, North KE, O'Connell JR, Schlessinger D, Thorsteinsdottir U, Strachan DP, Frayling T, Hirschhorn JN, Müller-Nurasyid M, Loos RJ. (2016). A principal component meta-analysis on multiple anthropometric traits identifies novel loci for body shape. Nature Communications, e13357, 1−11. DOI: 10.1038/ncomms13357.
1.1.
2016
Syed, Hamzah; Jorgensen, Andrea L.; Morris, Andrew P. (2016). Evaluation of methodology for the analysis of 'time-to-event' data in pharmacogenomic genome-wide association studies. Pharmacogenomics, 8, 907−915.10.2217/pgs.16.19.
1.1.
2016
Horikoshi, Momoko; Beaumont, Robin N.; Day, Felix R.; Warrington, Nicole M.; Kooijman, Marjolein N.; Fernandez-Tajes, Juan; Feenstra, Bjarke; van Zuydam, Natalie R.; Gaulton, Kyle J.; Grarup, Niels; Bradfield, Jonathan P.; Strachan, David P.; Li-Gao, Ruifang; Ahluwalia, Tarunveer S.; Kreiner, Eskil; Rueedi, Rico; Lyytikainen, Leo-Pekka; Cousminer, Diana L.; Wu, Ying; Thiering, Elisabeth ... Freathy, Rachel M. (2016). Genome-wide associations for birth weight and correlations with adult disease. Nature, 7624, 248−268.10.1038/nature19806.
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2016
Walford, Geoffrey A.; Gustafsson, Stefan; Rybin, Denis; Stancakova, Alena; Chen, Han; Liu, Ching-Ti; Hong, Jaeyoung; Jensen, Richard A.; Rice, Ken; Morris, Andrew P.; Magi, Reedik; Toenjes, Anke; Prokopenko, Inga; Kleber, Marcus E.; Delgado, Graciela; Silbernagel, Guenther; Jackson, Anne U.; Appel, Emil V.; Grarup, Niels; Lewis, Joshua P. ... Florez, Jose C. (2016). Genome-Wide Association Study of the Modified Stumvoll Insulin Sensitivity Index Identifies BCL2 and FAM19A2 as Novel Insulin Sensitivity Loci. Diabetes, 10, 3200−3211.10.2337/db16-0199.
1.1.
2016
Ek, Weronica E.; Hedman, Asa K.; Enroth, Stefan; Morris, Andrew P.; Lindgren, Cecilia M.; Mahajan, Anubha; Gustafsson, Stefan; Gyllensten, Ulf; Lind, Lars; Johansson, Asa (2016). Genome-wide DNA methylation study identifies genes associated with the cardiovascular biomarker GDF-15. Human Molecular Genetics, 4, 817−827.10.1093/hmg/ddv511.
1.1.
2016
Chauhan, Ganesh; Arnold, Corey R.; Chu, Audrey Y.; Fornage, Myriam; Reyahi, Azadeh; Bis, Joshua C.; Havulinna, Ald S.; Sargurupremraj, Muralidharan; Smith, Albert Vernon; Adams, Hieab H. H.; Choi, Seung Hoan; Pulit, Sara L.; Trompet, Stella; Garcia, Melissa E.; Manichaikul, Ani; Teumer, Alexander; Gustafsson, Stefan; Bartz, Traci M.; Bellenguez, Celine; Vidal, Jean Sebastien ... Debette, Stephanie (2016). Identification of additional risk loci for stroke and small vessel disease: a meta-analysis of genome-wide association studies. The Lancet Neurology, 7, 695−707. DOI: 10.1016/S1474-4422(16)00102-2.
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Prins, Bram. P.; Abbasi, Ali; Wong, Anson; Vaez, Ahmad; Nolte, Ilja; Franceschini, Nora; Stuart, Philip E.; Achury, Javier Guterriez; Mistry, Vanisha; Bradfield, Jonathan P.; Valdes, Ana M.; Bras, Jose; Shatunov, Aleksey; Lu, Chen; Han, Buhm; Raychaudhuri, Soumya; Bevan, Steve; Mayes, Maureen D.; Tsoi, Lam C.; Evangelou, Evangelos ... Alizadeh, Behrooz Z. (2016). Investigating the Causal Relationship of C-Reactive Protein with 32 Complex Somatic and Psychiatric Outcomes: A Large-Scale Cross-Consortium Mendelian Randomization Study. PLoS Medicine, 6, ARTN e1001976.10.1371/journal.pmed.1001976.
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2016
Cook, James P.; Morris, Andrew P. (2016). Multi-ethnic genome-wide association study identifies novel locus for type 2 diabetes susceptibility. European Journal of Human Genetics, 8, 1175−1180.10.1038/ejhg.2016.17.
1.1.
2016
Syed, Hamzah; Jorgensen, Andrea L.; Morris, Andrew P. (2016). SurvivalGWAS_Power: a user friendly tool for power calculations in pharmacogenetic studies with "time to event" outcomes. BMC Bioinformatics, ARTN 523.10.1186/s12859-016-1407-9.
1.1.
2016
Mahajan, Anubha; Rodan, Aylin R.; Le, Thu H.; Gaulton, Kyle J.; Haessler, Jeffrey; Stilp, Adrienne M.; Kamatani, Yoichiro; Zhu, Gu; Sofer, Tamar; Puri, Sanjana; Schellinger, Jeffrey N.; Chu, Pei-Lun; Cechova, Sylvia; van Zuydam, Natalie; Arnlov, Johan; Flessner, Michael F.; Giedraitis, Vilmantas; Heath, Andrew C.; Kubo, Michiaki; Larsson, Anders ... Franceschini, Nora (2016). Trans-ethnic Fine Mapping Highlights Kidney-Function Genes Linked to Salt Sensitivity. The American Journal of Human Genetics, 3, 636−646.10.1016/j.ajhg.2016.07.012.
1.1.
2016
Liu, Ching-Ti; Raghavan, Sridharan; Maruthur, Nisa; Kabagambe, Edmond Kato; Hong, Jaeyoung; Ng, Maggie C. Y.; Hivert, Marie-France; Lu, Yingchang; An, Ping; Bentley, Amy R.; Drolet, Anne M.; Gaulton, Kyle J.; Guo, Xiuqing; Armstrong, Loren L.; Irvin, Marguerite R.; Li, Man; Lipovich, Leonard; Rybin, Denis V.; Taylor, Kent D.; Agyemang, Charles ... Meigs, James B. (2016). Trans-ethnic Meta-analysis and Functional Annotation Illuminates the Genetic Architecture of Fasting Glucose and Insulin. The American Journal of Human Genetics, 1, 56−75.10.1016/j.ajhg.2016.05.006.
1.1.
2016
Horikoshi, Momoko; Pasquali, Lorenzo; Wiltshire, Steven; Huyghe, Jeroen R.; Mahajan, Anubha; Asimit, Jennifer L.; Ferreira, Teresa; Locke, Adam E.; Robertson, Neil R.; Wang, Xu; Sim, Xueling; Fujita, Hayato; Hara, Kazuo; Young, Robin; Zhang, Weihua; Choi, Sungkyoung; Chen, Han; Kaur, Ismeet; Takeuchi, Fumihiko; Fontanillas, Pierre ... Morris, Andrew P. (2016). Transancestral fine-mapping of four type 2 diabetes susceptibility loci highlights potential causal regulatory mechanisms. Human Molecular Genetics, 10, 2070−2081.10.1093/hmg/ddw048.
1.1.
2016
Asimit, Jennifer L.; Hatzikotoulas, Konstantinos; McCarthy, Mark; Morris, Andrew P.; Zeggini, Eleftheria (2016). Trans-ethnic study design approaches for fine-mapping. European Journal of Human Genetics, 9, 1330−1336.10.1038/ejhg.2016.1.
1.1.
2016
Loley C, Alver M, Assimes TL, Bjonnes A, Goel A, Gustafsson S, Hernesniemi J, Hopewell JC, Kanoni S, Kleber ME, Lau KW, Lu Y, Lyytikäinen LP, Nelson CP, Nikpay M, Qu L, Salfati E, Scholz M, Tukiainen T, Willenborg C, Won HH, Zeng L, Zhang W, Anand SS, Beutner F, Bottinger EP, Clarke R, Dedoussis G, Do R, Esko T, Eskola M, Farrall M, Gauguier D, Giedraitis V, Granger CB, Hall AS, Hamsten A, Hazen SL, Huang J, Kähönen M, Kyriakou T, Laaksonen R, Lind L, Lindgren C, Magnusson PK, Marouli E, Mihailov E, Morris AP, Nikus K, Pedersen N, Rallidis L, Salomaa V, Shah SH, Stewart AF, Thompson JR, Zalloua PA, Chambers JC, Collins R, Ingelsson E, Iribarren C, Karhunen PJ, Kooner JS, Lehtimäki T, Loos RJ, März W, McPherson R, Metspalu A, Reilly MP, Ripatti S, Sanghera DK, Thiery J, Watkins H, Deloukas P, Kathiresan S, Samani NJ, Schunkert H, Erdmann J, König IR. (2016). No Association of Coronary Artery Disease with X-Chromosomal Variants in Comprehensive International Meta-Analysis. Scientific Reports, 6 (35278 ), 1−9.10.1038/srep35278.
1.1.
2016
Stitziel, Nathan O; Stirrups, Kathleen E; Masca, Nicholas G D; Erdmann, Jeanette; Ferrario, Paola G; König, Inke R; Weeke, Peter E; Webb, Thomas R; Auer, Paul L; Schick, Ursula M; Lu, Yingchang; Zhang, He; Dube, Marie-Pierre; Goel, Anuj; Farrall, Martin; Peloso, Gina M; Won, Hong-Hee; Do, Ron; van Iperen, Erik ... Schunkert, Heribert. (2016). Coding Variation in ANGPTL4, LPL, and SVEP1 and the Risk of Coronary Disease. New England Journal of Medicine, 374 (12), 1134−1144. DOI: 10.1056/NEJMoa1507652.
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2016
Surendran, Praveen; Drenos, Fotios; Young, Robin; Warren, Helen; Cook, James P; Manning, Alisa K; Grarup, Niels; Sim, Xueling; Barnes, Daniel R; Witkowska, Kate; Staley, James R; Tragante, Vinicius; Tukiainen, Taru; Yaghootkar, Hanieh; Masca, Nicholas; Freitag, Daniel F; Ferreira, Teresa; Giannakopoulou, Olga; Tinker, Andrew; Harakalova, Magdalena ... Munroe, Patricia B (2016). Trans-ancestry meta-analyses identify rare and common variants associated with blood pressure and hypertension. Nature Genetics, 48 (10), 1151−1161. DOI: 10.1038/ng.3654.
1.1.
2016
van der Laan, Sander W.; Fall, Tove; Soumare, Aicha; Teumer, Alexander; Sedaghat, Sanaz; Baumert, Jens; Zabaneh, Delilah; van Setten, Jessica; Isgum, Ivana; Galesloot, Tessel E.; Arpegard, Johannes; Amouyel, Philippe; Trompet, Stella; Waldenberger, Melanie; Doerr, Marcus; Magnusson, Patrik K.; Giedraitis, Vilmantas; Larsson, Anders; Morris, Andrew P.; Felix, Janine F. ... Asselbergs, Folkert W. (2016). Cystatin C and Cardiovascular Disease A Mendelian Randomization Study. Journal of the American College of Cardiology, 68 (9), 934−945.10.1016/j.jacc.2016.05.092.
1.1.
2016
Zondervan, Krina T.; Rahmioglu, Nilufer; Morris, Andrew P.; Nyholt, Dale R.; Montgomery, Grant W.; Becker, Christian M.; Missmer, Stacey A. (2016). Beyond Endometriosis Genome-Wide Association Study: From Genomics to Phenomics to the Patient. Seminars in Reproductive Medicine, 34 (4), 242−254.10.1055/s-0036-1585408.
1.1.
2016
Tyrrell, Jessica; Richmond, Rebecca C.; Palmer, Tom M.; Feenstra, Bjarke; Rangarajan, Janani; Metrustry, Sarah; Cavadino, Alana; Paternoster, Lavinia; Armstrong, Loren L.; De Silva, N. Maneka G.; Wood, Andrew R.; Horikoshi, Momoko; Geller, Frank; Myhre, Ronny; Bradfield, Jonathan P.; Kreiner-Moller, Eskil; Huikari, Ville; Painter, Jodie N.; Hottenga, Jouke-Jan; Allard, Catherine ... Freathy, Rachel M. (2016). Genetic Evidence for Causal Relationships Between Maternal Obesity-Related Traits and Birth Weight. JAMA: the journal of the American Medical Association, 315 (11), 1129−1140.10.1001/jama.2016.1975.
5.1.
2016
Uimari, Outi; Rahmioglu, Nilufer; Nyholt, Dale R.; Becker, Christian M.; Morris, Andrew P.; Montgomery, Grant W.; Zondervan, Krina T. (2016). Genome-Wide Pathway Analysis Highlights the Role of MAPK and Wnt Signaling Pathways in Endometriosis. Reproductive Sciences, 330A−330A.
5.1.
2016
Cook, James P.; Morris, Andrew P. (2016). Investigating Fine-Scale Population Structure in the United Kingdom BioBank. Genetic Epidemiology, 7, 611−612.
6.8.
2016
Knowles, Joshua W.; Xie, Weijia; Zhang, Zhongyang; Chennamsetty, Indumathi; Assimes, Themistocles L.; Paananen, Jussi; Hansson, Ola; Pankow, James; Goodarzi, Mark O.; Carcamo-Orive, Ivan; Morris, Andrew P.; Chen, Yii-Der I.; Maekinen, Ville-Petteri; Ganna, Andrea; Mahajan, Anubha; Guo, Xiuqing; Abbasi, Fahim; Greenawalt, Danielle M.; Lum, Pek; Molony, Cliona ... Quertermous, Thomas (2016). Identification and validation of N-acetyltransferase 2 as an insulin sensitivity gene (vol 125, pg 1, 2015). Journal of Clinical Investigation, 1, 403−403.
6.8.
2016
Stitziel, Nathan O.; Stirrups, Kathleen E.; Masca, Nicholas G. D.; Erdmann, Jeanette; Ferrario, Paola G.; Koenig, Inke R.; Weeke, Peter E.; Webb, Thomas R.; Auer, Paul L.; Schick, Ursula M.; Lu, Yingchang; Zhang, He; Dube, Marie-Pierre; Goel, Anuj; Farrall, Martin; Peloso, Gina M.; Won, Hong-Hee; Do, Ron; van Iperen, Erik; Kanoni, Stavroula ... Schunkert, Heribert (2016). Coding Variation in ANGPTL4, LPL, and SVEP1 and the Risk of Coronary Disease (vol 374, pg 1134, 2016). New England Journal of Medicine, 374 (12, 19), 1898−1898.
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2015
Horikoshi, M; Mӓgi, R; van, de, Bunt, M; Surakka, I; Sarin, AP; Mahajan, A; Marullo, L; Thorleifsson, G; Hӓgg, S; Hottenga, JJ; Ladenvall, C; Ried, JS; Winkler, TW; Willems, SM; Pervjakova, N; Esko, T; Beekman, M; Nelson, CP; Willenborg, C; Wiltshire, S ... ENGAGE, Consortium. (2015). Discovery and Fine-Mapping of Glycaemic and Obesity-Related Trait Loci Using High-Density Imputation. PLoS Genetics, 11 (7), e1005230. DOI: 10.1371/journal.pgen.1005230.
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2015
Surakka, I; Horikoshi, M; Mägi, R; Sarin, AP; Mahajan, A; Lagou, V; Marullo, L; Ferreira, T; Miraglio, B; Timonen, S; Kettunen, J; Pirinen, M; Karjalainen, J; Thorleifsson, G; Hägg, S; Hottenga, JJ; Isaacs, A; Ladenvall, C; Beekman, M; Esko, T ... ENGAGE, Consortium. (2015). The impact of low-frequency and rare variants on lipid levels. Nature Genetics, 47 (6), 589−597. DOI: 10.1038/ng.3300.
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2015
Rahmioglu, N.; Macgregor, S.; Drong, AW.; Hedman, AK.; Harris, HR.; Randall, JC.; Prokopenko, I.; The, International, Endogene, Consortium, (IEC); The, GIANT, Consortium; Nyholt, DR.; Morris, AP.; Montgomery, GW.; Missmer, SA.; Lindgren, CM.; Zondervan, KT.; The, International, Endogene, Consortium, IEC, The, GIANT, Consortium. (2015). Genome-wide enrichment analysis between endometriosis and obesity-related traits reveals novel susceptibility loci. Human Molecular Genetics, 24 (4), 1185−1199. DOI: 10.1093/hmg/ddu516.
1.1.
2015
The, Coffee, and, Caffeine, Genetics, Consortium; Cornelis, MC; Byrne, EM; Esko, T; Nalls, MA; Ganna, A; Paynter, N; Monda, KL; Amin, N; Fischer, K; Renstrom, F; Ngwa, JS; Huikari, V; Cavadino, A; Nolte, IM; Teumer, A; Yu, K; Marques-Vidal, P; Rawal, R; Manichaikul, A ... Chasman, DI. (2015). Genome-wide meta-analysis identifies six novel loci associated with habitual coffee consumption. Molecular Psychiatry, 20 (5), 647−656. DOI: 10.1038/mp.2014.107.
1.1.
2015
Gaulton, Kyle J; Ferreira, Teresa; Lee, Yeji; Raimondo, Anne; Mägi, Reedik; Reschen, Michael E; Mahajan, Anubha; Locke, Adam; Rayner, N William; Robertson, Neil; Scott, Robert A; Prokopenko, Inga; Scott, Laura J; Green, Todd; Sparso, Thomas; Thuillier, Dorothee; Yengo, Loic; Grallert, Harald; Wahl, Simone; Frånberg, Mattias ... , (2015). Genetic fine mapping and genomic annotation defines causal mechanisms at type 2 diabetes susceptibility loci. Nature Genetics, 47 (12), 1415−1425. DOI: 10.1038/ng.3437.
1.1.
2015
Locke, AE.; Kahali, B.; Berndt, SI.; Justice, AE.; Pers, TH.; Day, FR.; Powell, C.; Vedantam, S.; Buchkovich, ML.; Yang, J.; Croteau-Chonka, DC.; Esko, T.; Fall, T.; Ferreira, T.; Gustafsson, S.; Kutalik, Z.; Luan, J.; Mägi, R.; Randall, JC.; Winkler, TW. ... Speliotes, EK. (2015). Genetic studies of body mass index yield new insights for obesity biology. Nature, 518 (7538), 197−206. DOI: 10.1038/nature14177.
1.1.
2015
Shungin, D; Winkler, TW; Croteau-Chonka, DC; Ferreira, T; Locke, AE; Mägi, R; Strawbridge, RJ; Pers, TH; Fischer, K; Justice, AE; Workalemahu, T; Wu, JM; Buchkovich, ML; Heard-Costa, NL; Roman, TS; Drong, AW; Song, C; Gustafsson, S; Day, FR; Esko, T ... Mohlke, KL. (2015). New genetic loci link adipose and insulin biology to body fat distribution. Nature, 518 (7538), 187−196. DOI: 10.1038/nature14132.
1.1.
2015
Nikpay, M; Goel, A; Won, HH; Hall, LM; Willenborg, C; Kanoni, S; Saleheen, D; Kyriakou, T; Nelson, CP; Hopewell, JC; Webb, TR; Zeng, L; Dehghan, A; Alver, M; Armasu, SM; Auro, K; Bjonnes, A; Chasman, DI; Chen, S; Ford, I ... Farrall, M. (2015). A comprehensive 1000 Genomes–based genome-wide association meta-analysis of coronary artery disease. Nature Genetics, 47 (10), 1121−1130. DOI: 10.1038/ng.3396.
1.1.
2015
Wain, LV; Shrine, N; Miller, S; Jackson, VE; Ntalla, I; Artigas, MS; Billington, CK; Kheirallah, AK; Allen, R; Cook, JP; Probert, K; Obeidat, M; Bosse, Y; Hao, K; Postma, DS; Pare, PD; Ramasamy, A; Magi, R; Mihailov, E; Reinmaa, E Melen, E ... Hall, IP (2015). Novel insights into the genetics of smoking behaviour, lung function, and chronic obstructive pulmonary disease (UK BiLEVE): a genetic association study in UK Biobank. The Lancet Respiratory Medicine, 3 (10), 769−781.10.1016/S2213-2600(15)00283-0.
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2015
Lunetta, KL; Day, FR; Sulem, P; Ruth, KS; Tung, JY; Hinds, DA; Esko, T; Elks, CE; Altmaier, E; He, C; Huffman, JE; Mihailov, E; Porcu, E; Robino, A; Rose, LM; Schick, UM; Stolk, L; Teumer, A; Thompson, DJ; Traglia, M ... Perry, JR. (2015). Rare coding variants and X-linked loci associated with age at menarche. Nature Communications, 6 (7756), 1−7. DOI: 10.1038/ncomms8756.
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2015
Joshi, Peter K.; Esko, Tõnu; Mattsson, Hannele; Eklund, Niina; Gandin, Ilaria; Nutile, Teresa; Jackson, Anne U.; Schurmann, Claudia; Smith, Albert V.; Zhang, Weihua; Okada, Yukinori; Stancakova, Alena; Faul, Jessica D.; Zhao, Wei; Bartz, Traci M.; Concas, Maria Pina; Franceschini, Nora; Enroth, Stefan; Vitart, Veronique; Trompet, Stella ... Wilson, James F. (2015). Directional dominance on stature and cognition in diverse human populations. Nature, 523 (7561), 459−476. DOI: 10.1038/nature14618.
1.1.
2015
Asimit, Jennifer L.; Panoutsopoulou, Kalliope; Wheeler, Eleanor; Berndt, Sonja I.; Cordell, Heather J.; Morris, Andrew P.; Zeggini, Eleftheria; Barroso, Ines (2015). A Bayesian Approach to the Overlap Analysis of Epidemiologically Linked Traits. Genetic Epidemiology, 39 (8), 624−634.10.1002/gepi.21919.
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2015
Artigas, Maria Soler; Wain, Louise V.; Miller, Suzanne; Kheirallah, Abdul Kader; Huffman, Jennifer E.; Ntalla, Ioanna; Shrine, Nick; Obeidat, Ma'en; Trochet, Holly; McArdle, Wendy L.; Alves, Alexessander Couto; Hui, Jennie; Zhao, Jing Hua; Joshi, Peter K.; Teumer, Alexander; Albrecht, Eva; Imboden, Medea; Rawal, Rajesh; Lopez, Lorna M.; Marten, Jonathan ... Zeggini, Eleftheria (2015). Sixteen new lung function signals identified through 1000 Genomes Project reference panel imputation. Nature Communications, 6 (8658), 1−12.10.1038/ncomms9658.
1.1.
2015
van de Bunt, Martijn; Cortes, Adrian; Brown, Matthew A.; Morris, Andrew P.; McCarthy, Mark I. (2015). Evaluating the Performance of Fine-Mapping Strategies at Common Variant GWAS Loci. PLoS Genetics, 11 (9), ARTN e1005535.10.1371/journal.pgen.1005535.
1.1.
2015
Lu, Yi; Cuellar-Partida, Gabriel; Painter, Jodie N.; Nyholt, Dale R.; Morris, Andrew P.; Fasching, Peter A.; Hein, Alexander; Burghaus, Stefanie; Beckmann, Matthias W.; Lambrechts, Diether; Van Nieuwenhuysen, Els; Vergote, Ignace; Vanderstichele, Adriaan; Doherty, Jennifer Anne; Rossing, Mary Anne; Wicklund, Kristine G.; Chang-Claude, Jenny; Eilber, Ursula; Rudolph, Anja; Wang-Gohrke, Shan ... MacGregor, Stuart (2015). Shared genetics underlying epidemiological association between endometriosis and ovarian cancer. Human Molecular Genetics, 24 (20), 5955−5964.10.1093/hmg/ddv306.
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2015
Liu, Jimmy Z.; van Sommeren, Suzanne; Huang, Hailiang; Ng, Siew C.; Alberts, Rudi; Takahashi, Atsushi; Ripke, Stephan; Lee, James C.; Jostins, Luke; Shah, Tejas; Abedian, Shifteh; Cheon, Jae Hee; Cho, Judy; Daryani, Naser E.; Franke, Lude; Fuyuno, Yuta; Hart, Ailsa; Juyal, Ramesh C.; Juyal, Garima; Kim, Won Ho ... Weersma, Rinse K. (2015). Association analyses identify 38 susceptibility loci for inflammatory bowel disease and highlight shared genetic risk across populations. Nature Genetics, 47 (9), 979−990.10.1038/ng.3359.
1.1.
2015
Boukari, Yamina; Scurr, David J.; Qutachi, Omar; Morris, Andrew P.; Doughty, Stephen W.; Rahman, Cheryl V.; Billa, Nashiru (2015). Physicomechanical properties of sintered scaffolds formed from porous and protein-loaded poly(DL-lactic-co-glycolic acid) microspheres for potential use in bone tissue engineering. Journal of Biomaterials Science Polymer Edition, 26 (12), 796−811.10.1080/09205063.2015.1058696.
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2015
Ng, Esther; Salihovic, Samira; Lind, P. Monica; Mahajan, Anubha; Syvanen, Anne-Christine; Axelsson, Tomas; Ingelsson, Erik; Lindgren, Cecilia M.; van Bavel, Bert; Morris, Andrew P.; Lind, Lars (2015). Genome-wide association study of plasma levels of polychlorinated biphenyls disclose an association with the CYP2B6 gene in a population-based sample. Environmental Research, 140, 95−101.10.1016/j.envres.2015.03.022.
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2015
Sapkota, Yadav; Attia, John; Gordon, Scott D.; Henders, Anjali K.; Holliday, Elizabeth G.; Rahmioglu, Nilufer; MacGregor, Stuart; Martin, Nicholas G.; McEvoy, Mark; Morris, Andrew P.; Scott, Rodney J.; Zondervan, Krina T.; Montgomery, Grant W.; Nyholt, Dale R. (2015). Genetic burden associated with varying degrees of disease severity in endometriosis. Molecular Human Reproduction, 21 (7), 594−602.10.1093/molehr/gav021.
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Knowles, Joshua W.; Xie, Weijia; Zhang, Zhongyang; Chennemsetty, Indumathi; Assimes, Themistocles L.; Paananen, Jussi; Hansson, Ola; Pankow, James; Goodarzi, Mark O.; Carcamo-Orive, Ivan; Morris, Andrew P.; Chen, Yii-Der I.; Maekinen, Ville-Petteri; Ganna, Andrea; Mahajan, Anubha; Guo, Xiuqing; Abbasi, Fahim; Greenawalt, Danielle M.; Lum, Pek; Molony, Cliona ... Quertermous, Thomas (2015). Identification and validation of N-acetyltransferase 2 as an insulin sensitivity gene. Journal of Clinical Investigation, 125 (4), 1739−1751. DOI: 10.1172/JCI74692.
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den Hoed, Marcel; Strawbridge, Rona J.; Almgren, Peter; Gustafsson, Stefan; Axelsson, Tomas; Engstrom, Gunnar; de Faire, Ulf; Hedblad, Bo; Humphries, Steve E.; Lindgren, Cecilia M.; Morris, Andrew P.; Ostling, Gerd; Syvanen, Ann-Christine; Tremoli, Elena; Hamsten, Anders; Ingelsson, Erik; Melander, Olle; Lind, Lars (2015). GWAS-identified loci for coronary heart disease are associated with intima-media thickness and plaque presence at the carotid artery bulb. Atherosclerosis, 239 (20), 304−310.10.1016/j.atherosclerosis.2015.01.032.
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Mahajan, Anubha; Sim, Xueling; Ng, Hui Jin; Manning, Alisa; Rivas, Manuel A.; Highland, Heather M.; Locke, Adam E.; Grarup, Niels; Im, Hae Kyung; Cingolani, Pablo; Flannick, Jason; Fontanillas, Pierre; Fuchsberger, Christian; Gaulton, Kyle J.; Teslovich, Tanya M.; Rayner, N. William; Robertson, Neil R.; Beer, Nicola L.; Rundle, Jana K.; Bork-Jensen, Jette ... Gloyn, Anna L. (2015). Identification and Functional Characterization of G6PC2 Coding Variants Influencing Glycemic Traits Define an Effector Transcript at the G6PC2-ABCB11 Locus. PLoS Genetics, 11 (1), ARTN e1004876.10.1371/journal.pgen.1004876.
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Sapkota, Yadav; Low, Siew-Kee; Attia, John; Gordon, Scott D.; Henders, Anjali K.; Holliday, Elizabeth G.; MacGregor, Stuart; Martin, Nicholas G.; McEvoy, Mark; Morris, Andrew P.; Takahashi, Atsushi; Scott, Rodney J.; Kubo, Michiaki; Zondervan, Krina T.; Montgomery, Grant W.; Nyholt, Dale R. (2015). Association between endometriosis and the interleukin 1A (ILIA) locus. Human Reproduction, 30 (1), 239−248.10.1093/humrep/deu267.
1.1.
2015
Ng, Esther; Lind, P. Monica; Lindgren, Cecilia; Ingelsson, Erik; Mahajan, Anubha; Morris, Andrew; Lind, Lars (2015). Genome-wide association study of toxic metals and trace elements reveals novel associations. Human Molecular Genetics, 24 (16), 4739−4745.10.1093/hmg/ddv190.
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Dumanski, Jan P.; Rasi, Chiara; Lonn, Mikael; Davies, Hanna; Ingelsson, Martin; Giedraitis, Vilmantas; Lannfelt, Lars; Magnusson, Patrik K. E.; Lindgren, Cecilia M.; Morris, Andrew P.; Cesarini, David; Johannesson, Magnus; Janson, Eva Tiensuu; Lind, Lars; Pedersen, Nancy L.; Ingelsson, Erik; Forsberg, Lars A. (2015). Smoking is associated with mosaic loss of chromosome Y. Science, 347 (6217), 81−83.10.1126/science.1262092.
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Winkler, Thomas W.; Justice, Anne E.; Graff, Mariaelisa; Barata, Llilda; Feitosa, Mary F.; Chu, Su; Czajkowski, Jacek; Esko, Tonu; Fall, Tove; Kilpelainen, Tuomas O.; Lu, Yingchang; Magi, Reedik; Mihailov, Evelin; Pers, Tune H.; Rueeger, Sina; Teumer, Alexander; Ehret, Georg B.; Ferreira, Teresa; Heard-Costa, Nancy L.; Karjalainen, Juha ... Loos, Ruth J. F. (2015). The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study. PLoS Genetics, 11 (10), ARTN e1005378.10.1371/journal.pgen.1005378.
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Kaakinen, M.; Maegi, R.; Fischer, K.; Jarvelin, M. -R.; Morris, A. P.; Prokopenko, I. (2015). A Novel Method and Software Tool for Genome-Wide Multi-Phenotype Analysis of Rare Variants. Human Heredity, 79: 43rd European Mathematical Genetics Meeting (EMGM), Brest, FRANCE, APR 16-17, 2015. Karger, 39−39. (1).
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Dumanski, Jan P.; Rasi, Chiara; Lonn, Mikael; Davies, Hanna; Ingelsson, Martin; Giedraitis, Vilmantas; Lannfelt, Lars; Magnusson, Patrik K. E.; Lindgren, Cecilia M.; Morris, Andrew P.; Cesarini, David; Johannesson, Magnus; Janson, Eva Tiensuu; Lind, Lars; Pedersen, Nancy L.; Ingelsson, Erik; Forsberg, Lars A. (2015). Smoking is associated with mosaic loss of chromosome Y. Cancer Research, 75, 4683. DOI: 10.1158/1538-7445.AM2015-4683.
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Kaakinen, Marika; Magi, Reedik; Fischer, Krista; Jarvelin, Marjo-Riitta; Morris, Andrew P.; Prokopenko, Inga (2015). MARV: Anovel method and software tool for genome-wide multi-phenotype analysis of rare variants. BMC Bioinformatics, 18 (1), 560−560. DOI: 10.1186/s12859-017-1530-2.
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Cook, James P.; Morris, Andrew P. (2015). Methodology for the analysis of multi-ethnic genome-wide association studies. Genetic Epidemiology, 39 (7), 540−541.
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Allen, Richard J.; Wain, Louise V.; Shrine, Nick; Miller, Suzanne; Jackson, Victoria E.; Ntalla, Ioanna; Artigas, Maria Soler; Cook, James P.; Morris, Andrew P.; Zeggini, Eleftheria; Marchini, Jonathan; De-Loukas, Panos; Hansell, Anna; Hubbard, Richard; Pavord, Ian; Thompson, Neil C.; Strachan, David P.; Hall, Ian P.; Tobin, Martin D. (2015). Shared polygenic effects of FEV1 in the first genetic study in UK Biobank. Genetic Epidemiology, 39 (7), 529−530.
5.1.
2015
Raghavan, Sridharan; Hong, Jaeyoung; Hara, Kazuo; Maruthur, Nisa M.; Lipovich, Leonard; Guo, Xiuqing; Florez, Jose C.; Loos, Ruth J. F.; Dupuis, Josee; Liu, Ching-Ti; Morris, Andrew P.; Meigs, James B. (2015). Trans-ethnic Fine-Mapping Implicates Regulatory Variation at Glycemic Quantitative Trait Loci: The African-American Glucose and Insulin Genetic Epidemiology (AAGILE) Consortium. Diabetes, 64 (1, Supplement ), A455−A456.
5.1.
2015
Horikoshi, Momoko; Carstensen, Lisbeth; Strachan, David P.; Kooijman, Marjolein N.; Boh, Eileen T. H.; Joshi, Peter K.; Van Leeuwen, Elisabeth M.; Bradfield, Jonathan P.; Pitkaenen, Niina; Lyytikaeinen, Leo-Pekka; Lindi, Virpi; Joro, Raimo; Kreiner-Moller, Eskil; Thiering, Elisabeth; Rueedi, Rico; Ang, Wei; Wang, Carol; Ntalla, Ioanna; Wu, Ying; Vilortejedor, Natalia ... Morris, Andrew P. (2015). Large Scale Genome-Wide Association Study for Birth Weight Finds Eight Novel Loci Extending the Genetic Link between Early Growth and Type 2 Diabetes. Diabetes, 64 (1, Supplement ), A6−A7.
5.1.
2015
Magi, Reedik; Scott, Robert A.; Morris, Andrew P.; Marullo, Letizia; Gaulton, Kyle; Boehnke, Michael; Dupuis, Josee; Mccarthy, Mark I.; Scott, Laura J.; Prokopenko, Inga (2015). Genome-Wide Association Study Imputed to 1000 Genomes Project Reference Panels Reveals 17 Novel Associations with Type 2 Diabetes. Diabetes, 64 (1, Supplement ), A5−A5.
5.1.
2015
Yin, Peng; Jorgensen, Andrea; Morris, Andrew P.; Turner, Richard; Fitzgerald, Richard; Stables, Rod; Hanson, Anita; Pirmohamed, Munir (2015). Pharmacogenetics of Acute Coronary Syndrome. Genetic Epidemiology, 39 (7), 596−596.
6.8.
2015
Morris, Andrew P. (2015). Fine Mapping of Type 2 Diabetes Susceptibility Loci (vol 14, 549, 2014). Current Diabetes Reports, 15 (1), UNSP 575. DOI: 10.1007/s11892-014-0575-0.
1.1.
2014
Winkler, T.W.; Day, FR.; Croteau-Chonka, DC.; Wood, AR.; Locke, AE.; Magi, R.; Ferreira, T.; Fall, T.; Graff, M.; Justice, AE.; Luan, JA.; Gustafsson, S.; Randall, JC.; Vedantam, S.; Workalemahu, T.; Kilpelainen, TO.; Scherag, A.; Esko, T.; Kutalik, Z.; Heid, IM. ... Loos, RJF (2014). Quality control and conduct of genome-wide association meta-analyses. Nature Protocols, 9 (5), 1192−1212. DOI: 10.1038/nprot.2014.071.
1.1.
2014
Wood, AR; Esko, T; Yang, J; Vedantam, S; Pers, TH; Gustafsson, S; Chu, AY; Estrada, K; Luan, J; Kutalik, Z; Amin, N; Buchkovich, ML; Croteau-Chonka, DC; Day, FR; Duan, Y14; Fall, T; Fehrmann, R; Ferreira, T; Jackson, AU; Karjalainen, J ... Frayling, TM. (2014). Defining the role of common variation in the genomic and biological architecture of adult human height. Nature Genetics, 46 (11), 1173−1186. DOI: 10.1038/ng.3097.
1.1.
2014
Yuan, Wei; Xia, Yudong; Bell, Christopher G.; Yet, Idil; Ferreira, Teresa; Ward, Kirsten J.; Gao, Fei; Loomis, A. Katrina; Hyde, Craig L.; Wu, Honglong; Lu, Hanlin; Liu, Yuan; Small, Kerrin S.; Vinuela, Ana; Morris, Andrew P.; Berdasco, Maria; Esteller, Manel; Brosnan, M. Julia; Deloukas, Panos; McCarthy, Mark I. ... Spector, Tim D. (2014). An integrated epigenomic analysis for type 2 diabetes susceptibility loci in monozygotic twins. Nature Communications, 5, ARTN 5719.10.1038/ncomms6719.
1.1.
2014
Keller, Margaux F.; Reiner, Alexander P.; Okada, Yukinori; van Rooij, Frank J. A.; Johnson, Andrew D.; Chen, Ming-Huei; Smith, Albert V.; Morris, Andrew P.; Tanaka, Toshiko; Ferrucci, Luigi; Zonderman, Alan B.; Lettre, Guillaume; Harris, Tamara; Garcia, Melissa; Bandinelli, Stefania; Qayyum, Rehan; Yanek, Lisa R.; Becker, Diane M.; Becker, Lewis C.; Kooperberg, Charles ... Nalls, Mike A. (2014). Trans-ethnic meta-analysis of white blood cell phenotypes. Human Molecular Genetics, 23 (25), 6944−6960.10.1093/hmg/ddu401.
1.1.
2014
Moutsianas, Loukas; Morris, Andrew P. (2014). Methodology for the analysis of rare genetic variation in genome-wide association and re-sequencing studies of complex human traits. Briefings in Functional Genomics, 13 (5), 362−370.10.1093/bfgp/elu012.
1.1.
2014
Xi, Bo; Takeuchi, Fumihiko; Meirhaeghe, Aline; Kato, Norihiro; Chambers, John C.; Morris, Andrew P.; Cho, Yoon Shin; Zhang, Weihua; Mohlke, Karen L.; Kooner, Jaspal S.; Shu, Xiao Ou; Pan, Hongwei; Tai, E. Shyong; Pan, Haiyan; Wu, Jer-Yuarn; Zhou, Donghao; Chandak, Giriraj R. (2014). Associations of genetic variants in/near body mass index-associated genes with type 2 diabetes: a systematic meta-analysis. Clinical Endocrinology, 81 (5), 702−710.10.1111/cen.12428.
1.1.
2014
Rahmioglu, Nilufer; Nyholt, Dale R.; Morris, Andrew P.; Missmer, Stacey A.; Montgomery, Grant W.; Zondervan, Krina T. (2014). Genetic variants underlying risk of endometriosis: insights from meta-analysis of eight genome-wide association and replication datasets. Human Reproduction Update, 20 (5), 702−716.10.1093/humupd/dmu015.
1.1.
2014
Tang, Wenbo; Kowgier, Matthew; Loth, Daan W.; Artigas, Maria Soler; Joubert, Bonnie R.; Hodge, Emily; Gharib, Sina A.; Smith, Albert V.; Ruczinski, Ingo; Gudnason, Vilmundur; Mathias, Rasika A.; Harris, Tamara B.; Hansel, Nadia N.; Launer, Lenore J.; Barnes, Kathleen C.; Hansen, Joyanna G.; Albrecht, Eva; Aldrich, Melinda C.; Allerhand, Michael; Barr, R. Graham ... Cassano, Patricia A. (2014). Large-Scale Genome-Wide Association Studies and Meta-Analyses of Longitudinal Change in Adult Lung Function. PLoS ONE, 9 (7), ARTN e100776.10.1371/journal.pone.0100776.
1.1.
2014
Lind, Lars; Penell, Johanna; Syvaenen, Anne-Christine; Axelsson, Tomas; Ingelsson, Erik; Morris, Andrew P.; Lindgren, Cecilia; Salihovic, Samira; van Bavel, Bert; Lind, P. Monica (2014). Genetic variation in the CYP1A1 gene is related to circulating PCB118 levels in a population-based sample. Environmental Research, 133, 135−140.10.1016/j.envres.2014.05.017.
1.1.
2014
Langenberg, Claudia; Sharp, Stephen J.; Franks, Paul W.; Scott, Robert A.; Deloukas, Panos; Forouhi, Nita G.; Froguel, Philippe; Groop, Leif C.; Hansen, Torben; Palla, Luigi; Pedersen, Oluf; Schulze, Matthias B.; Tormo, Maria-Jose; Wheeler, Eleanor; Agnoli, Claudia; Arriola, Larraitz; Barricarte, Aurelio; Boeing, Heiner; Clarke, Geraldine M.; Clavel-Chapelon, Francoise ... Wareham, Nicholas J. (2014). Gene-Lifestyle Interaction and Type 2 Diabetes: The EPIC InterAct Case-Cohort Study. PLoS Medicine, 11 (5), ARTN e1001647.10.1371/journal.pmed.1001647.
1.1.
2014
Loth, Daan W.; Artigas, Maria Soler; Gharib, Sina A.; Wain, Louise V.; Franceschini, Nora; Koch, Beate; Pottinger, Tess D.; Smith, Albert Vernon; Duan, Qing; Oldmeadow, Chris; Lee, Mi Kyeong; Strachan, David P.; James, Alan L.; Huffman, Jennifer E.; Vitart, Veronique; Ramasamy, Adaikalavan; Wareham, Nicholas J.; Kaprio, Jaakko; Wang, Xin-Qun; Trochet, Holly ... London, Stephanie J. (2014). Genome-wide association analysis identifies six new loci associated with forced vital capacity. Nature Genetics, 46 (7), 669−677.10.1038/ng.3011.
1.1.
2014
Penell, Johanna; Lind, Lars; Fall, Tove; Syvanen, Anne-Christine; Axelsson, Tomas; Lundmark, Per; Morris, Andrew P.; Lindgren, Cecilia; Mahajan, Anubha; Salihovic, Samira; van Bavel, Bert; Ingelsson, Erik; Lind, P. Monica (2014). Genetic variation in the CYP2B6 Gene is related to circulating 2,2 ',4,4 '-tetrabromodiphenyl ether (BDE-47) concentrations: an observational population-based study. Environmental Health, 13 (1), ARTN 34.10.1186/1476-069X-13-34.
1.1.
2014
Forsberg, Lars A.; Rasi, Chiara; Malmqvist, Niklas; Davies, Hanna; Pasupulati, Saichand; Pakalapati, Geeta; Sandgren, Johanna; de Stahl, Teresita Diaz; Zaghlool, Ammar; Giedraitis, Vilmantas; Lannfelt, Lars; Score, Joannah; Cross, Nicholas C. P.; Absher, Devin; Janson, Eva Tiensuu; Lindgren, Cecilia M.; Morris, Andrew P.; Ingelsson, Erik; Lind, Lars; Dumanski, Jan P. (2014). Mosaic loss of chromosome Y in peripheral blood is associated with shorter survival and higher risk of cancer. Nature Genetics, 46 (6), 624−628.10.1038/ng.2966.
1.1.
2014
Flannick, Jason; Thorleifsson, Gudmar; Beer, Nicola L.; Jacobs, Suzanne B. R.; Grarup, Niels; Burtt, Noel P.; Mahajan, Anubha; Fuchsberger, Christian; Atzmon, Gil; Benediktsson, Rafn; Blangero, John; Bowden, Don W.; Brandslund, Ivan; Brosnan, Julia; Burslem, Frank; Chambers, John; Cho, Yoon Shin; Christensen, Cramer; Douglas, Desiree A.; Duggirala, Ravindranath ... Altshuler, David (2014). Loss-of-function mutations in SLC30A8 protect against type 2 diabetes. Nature Genetics, 46 (4), 357−365.10.1038/ng.2915.
1.1.
2014
Bolton, Jennifer L.; Hayward, Caroline; Direk, Nese; Lewis, John G.; Hammond, Geoffrey L.; Hill, Lesley A.; Anderson, Anna; Huffman, Jennifer; Wilson, James F.; Campbell, Harry; Rudan, Igor; Wright, Alan; Hastie, Nicholas; Wild, Sarah H.; Velders, Fleur P.; Hofman, Albert; Uitterlinden, Andre G.; Lahti, Jari; Raikkonen, Katri; Kajantie, Eero ... Walker, Brian R. (2014). Genome Wide Association Identifies Common Variants at the SERPINA6/SERPINA1 Locus Influencing Plasma Cortisol and Corticosteroid Binding Globulin. PLoS Genetics, 10 (7), ARTN e1004474.10.1371/journal.pgen.1004474.
1.1.
2014
Kraja, Aldi T.; Chasman, Daniel I.; North, Kari E.; Reiner, Alexander P.; Yanek, Lisa R.; Kilpelainen, Tuomas O.; Smith, Jennifer A.; Dehghan, Abbas; Dupuis, Josee; Johnson, Andrew D.; Feitosa, Mary F.; Tekola-Ayele, Fasil; Chu, Audrey Y.; Nolte, Ilja M.; Dastani, Zari; Morris, Andrew; Pendergrass, Sarah A.; Sun, Yan V.; Ritchie, Marylyn D.; Vaez, Ahmad ... Borecki, Ingrid B. (2014). Pleiotropic genes for metabolic syndrome and inflammation. Molecular Genetics and Metabolism, 112 (4), 317−338.10.1016/j.ymgme.2014.04.007.
1.1.
2014
Mägi, Reedik; Metspalu, Andres; Mihailov, Evelin (2014). Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility. Nature Genetics, 46 (3), 234−244. DOI: 10.1038/ng.2897.
1.1.
2014
Becker, Jessica; Czamara, Darina; Scerri, Tom S.; Ramus, Franck; Csepe, Valeria; Talcott, Joel B.; Stein, John; Morris, Andrew; Ludwig, Kerstin U.; Hoffmann, Per; Honbolygo, Ferenc; Toth, Denes; Fauchereau, Fabien; Bogliotti, Caroline; Iannuzzi, Stephanie; Chaix, Yves; Valdois, Sylviane; Billard, Catherine; George, Florence; Soares-Boucaud, Isabelle ... Schumacher, Johannes (2014). Genetic analysis of dyslexia candidate genes in the European cross-linguistic NeuroDys cohort. European Journal of Human Genetics, 22 (5), 675−680.10.1038/ejhg.2013.199.
1.2.
2014
Morris, AP. (2014). Fine Mapping of Type 2 Diabetes Susceptibility Loci. Current Diabetes Reports, 14 (549), 1−8.10.1007/s11892-014-0549-2.
5.1.
2014
Morris, A. P.; Teslovich, T. M.; Ferreira, T.; Mahajan, A.; Lee, Y.; Rayner, N. W.); Magi, R. (2014). Fine-mapping type 2 diabetes susceptibility loci with high-density imputation. DIABETOLOGIA, 57: 50th EASD Annual Meeting, Vienna, Austria, 15-19.09.2014. Springer, S50−S51.
1.1.
2013
Fall, T.; Hagg, S.; Magi, R.; Ploner, A.; Fischer, K.; Horikoshi, M.; Sarin, AP.; Thorleifsson, G.; Ladenvall, C.; Kals, M.; Kuningas, M.; Draisma, HHM.; Ried, JS.; van Zuydam, NR.; Huikari, V.; Mangino, M.; Sonestedt, E.; Benyamin, B.; Nelson, CP.; Rivera, NV. ... Prokopenko, I. (2013). The Role of Adiposity in Cardiometabolic Traits: A Mendelian Randomization Analysis. PLoS Medicine, 10 (6), e1001474−e1001474. DOI: 10.1371/journal.pmed.1001474.
1.1.
2013
Deloukas, P; Kanoni, S; Willenborg, C; Farrall, M; Assimes, TL; Thompson, JR; Ingelsson, E; Saleheen, D; Erdmann, J; Goldstein, BA; Stirrups, K; König, IR; Cazier, JB; Johansson, A; Hall, AS; Lee, JY; Willer, CJ; Chambers, JC; Esko, T; Folkersen, L ... Samani, NJ (2013). Large-scale association analysis identifies new risk loci for coronary artery disease. Nature Genetics, 45 (1), 25−33. DOI: 10.1038/ng.2480.
1.1.
2013
Vimaleswaran, KS.; Berry, DJ.; Lu, C.; Tikkanen, E.; Pilz, S.; Hiraki, LT.; Cooper, JD.; Dastani, Z.; Li, R.; Houston, DK.; Wood, AR.; Michaëlsson, K.; Vandenput, L.; Zgaga, L.; Yerges-Armstrong, LM.; McCarthy, MI.; Dupuis, J.; Kaakinen, M.; Kleber, ME.; Jameson, K. ... Hyppönen, E. (2013). Causal relationship between obesity and vitamin D status: bi-directional Mendelian randomization analysis of multiple cohorts. PLoS Medicine, 10 (2), e1001383. DOI: 10.1371/journal.pmed.1001383.
1.1.
2013
Do, R; Willer, CJ; Schmidt, EM; Sengupta, S; Gao, C; Peloso, GM; Gustafsson, S; Kanoni, S; Ganna, A; Chen, J; Buchkovich, ML; Mora, S; Beckmann, JS; Bragg-Gresham, JL; Chang, HY; Demirkan, A; Den, Hertog, HM; Donnelly, LA; Ehret, GB; Esko, T ... Kathiresan, S. (2013). Common variants associated with plasma triglycerides and risk for coronary artery disease. Nature Genetics, 45 (11), 1345−1352 . DOI: 10.1038/ng.2795.
1.1.
2013
Global, Lipids, Genetics, Consortium; Willer, CJ; Schmidt, EM; Sengupta, S; Peloso, GM; Gustafsson, S; Kanoni, S; Ganna, A; Chen, J; Buchkovich, ML; Mora, S; Beckmann, JS; Bragg-Gresham, JL; Chang, HY; Demirkan, A; Den, Hertog, HM; Do, R; Donnelly, LA; Ehret, GB; Esko, T ... Abecasis, GR. (2013). Discovery and refinement of loci associated with lipid levels. Nature Genetics, 45 (11), 1274−1283. DOI: 10.1038/ng.2797.
1.1.
2013
Berndt, SI; Gustafsson, S; Mägi, R; Ganna, A; Wheeler, E; Feitosa, MF; Justice, AE; Monda, KL; Croteau-Chonka, DC; Day, FR; Esko, T; Fall, T; Ferreira, T; Gentilini, D; Jackson, AU; Luan, J; Randall, JC; Vedantam, S; Willer, CJ; Winkler, TW ... Ingelsson, E. (2013). Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture. Nature Genetics, 45 (5), 501−U69. DOI: 10.1038/ng.2606.
1.1.
2013
den Hoed, M; Eijgelsheim, M; Esko, T; Brundel, BJ; Peal, DS; Evans, DM; Nolte, IM; Segrè, AV; Holm, H; Handsaker, RE; Westra, HJ; Johnson, T; Isaacs, A; Yang, J; Lundby, A; Zhao, JH; Kim, YJ; Go, MJ; Almgren, P; Bochud, M ... Loos, RJ. (2013). Identification of heart rate-associated loci and their effects on cardiac conduction and rhythm disorders. Nature Genetics, 45 (6), 621.
1.1.
2013
Randall, JC; Winkler, TW; Kutalik, Z; Berndt, SI; Jackson, AU; Monda, KL; Kilpeläinen, TO; Esko, T; Mägi, R; Li, S; Workalemahu, T; Feitosa, MF; Croteau-Chonka, DC; Day, FR; Fall, T; Ferreira, T; Gustafsson, S; Locke, AE; Mathieson, I; Scherag, A ... Heid, IM (2013). Sex-stratified Genome-wide Association Studies Including 270,000 Individuals Show Sexual Dimorphism in Genetic Loci for Anthropometric Traits. PLoS Genetics, 9 (6), e1003500. DOI: 10.1371/journal.pgen.1003500.
1.1.
2013
Brandler, William M.; Morris, Andrew P.; Evans, David M.; Scerri, Thomas S.; Kemp, John P.; Timpson, Nicholas J.; St Pourcain, Beate; Smith, George Davey; Ring, Susan M.; Stein, John; Monaco, Anthony P.; Talcott, Joel B.; Fisher, Simon E.; Webber, Caleb; Paracchini, Silvia (2013). Common Variants in Left/Right Asymmetry Genes and Pathways Are Associated with Relative Hand Skill. PLoS Genetics, 9 (9), ARTN e1003751.10.1371/journal.pgen.1003751.
1.1.
2013
O'Seaghdha, Conall M.; Wu, Hongsheng; Yang, Qiong; Kapur, Karen; Guessous, Idris; Zuber, Annie Mercier; Koettgen, Anna; Stoudmann, Candice; Teumer, Alexander; Kutalik, Zoltan; Mangino, Massimo; Dehghan, Abbas; Zhang, Weihua; Eiriksdottir, Gudny; Li, Guo; Tanaka, Toshiko; Portas, Laura; Lopez, Lorna M.; Hayward, Caroline; Lohman, Kurt ... Bochud, Murielle (2013). Meta-Analysis of Genome-Wide Association Studies Identifies Six New Loci for Serum Calcium Concentrations. PLoS Genetics, 9 (9), ARTN e1003796.10.1371/journal.pgen.1003796.
1.1.
2013
Clarke, Geraldine M.; Rivas, Manuel A.; Morris, Andrew P. (2013). A Flexible Approach for the Analysis of Rare Variants Allowing for a Mixture of Effects on Binary or Quantitative Traits. PLoS Genetics, 8, ARTN e1003694.10.1371/journal.pgen.1003694.
1.1.
2013
Lam, Vincent Kwok Lim; Ma, Ronald Ching Wan; Lee, Heung Man; Hu, Cheng; Park, Kyong Soo; Furuta, Hiroto; Wang, Ying; Tam, Claudia Ha Ting; Sim, Xueling; Ng, Daniel Peng-Keat; Liu, Jianjun; Wong, Tien-Yin; Tai, E. Shyong; Morris, Andrew P.; Tang, Nelson Leung Sang; Woo, Jean; Leung, Ping Chung; Kong, Alice Pik Shan; Ozaki, Risa; Jia, Wei Ping ... Chan, Juliana Chung Ngor (2013). Genetic Associations of Type 2 Diabetes with Islet Amyloid Polypeptide Processing and Degrading Pathways in Asian Populations. PLoS ONE, 8 (6), ARTN e62378.10.1371/journal.pone.0062378.
1.1.
2013
Saxena, Richa; Saleheen, Danish; Been, Latonya F.; Garavito, Martha L.; Braun, Timothy; Bjonnes, Andrew; Young, Robin; Ho, Weang Kee; Rasheed, Asif; Frossard, Philippe; Sim, Xueling; Hassanali, Neelam; Radha, Venkatesan; Chidambaram, Manickam; Liju, Samuel; Rees, Simon D.; Ng, Daniel Peng-Keat; Wong, Tien-Yin; Yamauchi, Toshimasa; Hara, Kazuo ... Sanghera, Dharambir K. (2013). Genome-Wide Association Study Identifies a Novel Locus Contributing to Type 2 Diabetes Susceptibility in Sikhs of Punjabi Origin From India. Diabetes, 62 (5), 1746−1755.10.2337/db12-1077.
1.1.
2013
Travers, Mary E.; Mackay, Deborah J. G.; Nitert, Marloes Dekker; Morris, Andrew P.; Lindgren, Cecilia M.; Berry, Andrew; Johnson, Paul R.; Hanley, Neil; Groop, Leif C.; McCarthy, Mark I.; Gloyn, Anna L. (2013). Insights Into the Molecular Mechanism for 2 Diabetes Susceptibility at the KCNQ1 Locus From Temporal Changes in Imprinting Status in Human Islets. Diabetes, 62 (3), 987−992. DOI: 10.2337/db12-0819.
1.1.
2013
Andreassen, Ole A.; Djurovic, Srdjan; Thompson, Wesley K.; Schork, Andrew J.; Kendler, Kenneth S.; O'Donovan, Michael C.; Rujescu, Dan; Werge, Thomas; van de Bunt, Martijn; Morris, Andrew P.; McCarthy, Mark I.; Roddey, J. Cooper; McEvoy, Linda K.; Desikan, Rahul S.; Dale, Anders M. (2013). Improved Detection of Common Variants Associated with Schizophrenia by Leveraging Pleiotropy with Cardiovascular-Disease Risk Factors. The American Journal of Human Genetics, 92 (2), 197−209.10.1016/j.ajhg.2013.01.001.
1.1.
2013
Ma, R. C. W.; Hu, C.; Tam, C. H.; Zhang, R.; Kwan, P.; Leung, T. F.; Thomas, G. N.; Go, M. J.; Hara, K.; Sim, X.; Ho, J. S. K.; Wang, C.; Li, H.; Lu, L.; Wang, Y.; Li, J. W.; Wang, Y.; Lam, V. K. L.; Wang, J.; Yu, W. ... Jia, W. (2013). Genome-wide association study in a Chinese population identifies a susceptibility locus for type 2 diabetes at 7q32 near PAX4. Diabetologia, 56 (6), 1291−1305.10.1007/s00125-013-2874-4.
1.1.
2013
Albrechtsen, A.; Grarup, N.; Li, Y.; Sparso, T.; Tian, G.; Cao, H.; Jiang, T.; Kim, S. Y.; Korneliussen, T.; Li, Q.; Nie, C.; Wu, R.; Skotte, L.; Morris, A. P.; Ladenvall, C.; Cauchi, S.; Stancakova, A.; Andersen, G.; Astrup, A.; Banasik, K. ... Pedersen, O. (2013). Exome sequencing-driven discovery of coding polymorphisms associated with common metabolic phenotypes. Diabetologia, 56 (2), 298−310.10.1007/s00125-012-2756-1.
5.1.
2013
Lagou, V.; Mägi, R.; Surakka, I. ; Sarin, A. -P.; Horikoshi, M.; Thorleifsson, G. ; Hagg, S.; Beekman, M.; Ladenvall, C.; Hottenga, J. -J.; Ried, J. S.; McCarthy, M. I.Morris, A.; Ripatti, S.; Prokopenko, I. (2013). Pleiotropic effects on lipid levels and obesity identified in multi-trait meta-analysis of genome-wide association studies (GWAS) of type 2 diabetes related traits. DIABETOLOGIA, 56: 49th Annual Meeting of the European-Association-for-the-Study-of-Diabetes (EASD), Barcelona, SPAIN, SEP 23-27, 2013. Springer, S60−S60.
5.1.
2013
Horikoshi, M.; Mägi, R.; Surakka, I.; Sarin, A. -P.; Mahajan, A.; Marullo, L.; Ferreira, T. ; Esko, T.; Lindgren, C. M.; Morris, A. P.; McCarthy, M. I.; Ripatti, S.; Prokopenko, I; ENGAGE, Consortium. (2013). Large-scale genome-wide association meta-analysis of the 1000 genomes project imputed data identifies novel susceptibility loci for glycaemic and obesity traits. DIABETOLOGIA, 56: 49th Annual Meeting of the European-Association-for-the-Study-of-Diabetes (EASD), Barcelona, SPAIN, SEP 23-27, 2013. Springer, S60−S61.
1.1.
2012
Marquez, M; Huyvaert, M; Perry, JR; Pearson, RD; Falchi, M; Morris, AP; Vivequin, S; Lobbens, S; Yengo, L; Gaget, S; Pattou, F; Poulain-Godefroy, O; Charpentier, G; Carlsson, LM; Jacobson, P; Sjöström, L; Lantieri, O; Heude, B; Walley, A; Balkau, B ... Cauchi, S. (2012). Low-frequency variants in HMGA1 are not associated with type 2 diabetes risk. Diabetes, 61 (2), 524−530.10.2337/db11-0728.
1.1.
2012
Cho, YS; Chen, CH; Hu, C; Long, JR; Ong, RTH; Sim, XL; Takeuchi, F; Wu, Y; Go, MJ; Yamauchi, T; Chang, YC; Kwak, SH; Ma, RCW; Yamamoto, K; Adair, LS; Aung, T; Cai, QY; Chang, LC; Chen, YT; Gao, YT ... Seielstad, M. (2012). Meta-analysis of genome-wide association studies identifies eight new loci for type 2 diabetes in East Asians. Nature Genetics, 44 (1), 67−U97.10.1038/ng.1019.
1.1.
2012
Mägi, R; Asimit, JL; Day-Williams, AG; Zeggini, E; Morris, AP. (2012). Genome-Wide Association Analysis of Imputed Rare Variants: Application to Seven Common Complex Diseases. Genetic Epidemiology, 36 (8), 785−796.10.1002/gepi.21675.
1.1.
2012
the DIAbetes Genetics Replication And Meta-analysis (DIAGRAM), Consortium; Morris, AP; Voight, BF; Teslovich, TM; Ferreira, T; Segrè, AV; Steinthorsdottir, V; Strawbridge, RJ; Khan, H; Grallert, H; Mahajan, A; Prokopenko, I; Kang, HM; Dina, C; Esko, T; Fraser, RM; Kanoni, S; Kumar, A; Lagou, V; Langenberg, C ... McCarthy, MI. (2012). Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes. Nature Genetics, 981−990.10.1038/ng.2383.
1.1.
2012
Scott, RA.; Lagou, V.; Welch, RP.; Wheeler, E.; Montasser, ME.; Luan, J.; Mägi, R.; Strawbridge, RJ.; Rehnberg, E.; Gustafsson, S.; Kanoni, S.; Rasmussen-Torvik, LJ.; Yengo, L.; Lecoeur, C.; Shungin, D.; Sanna, S.; Sidore, C.; Johnson, PC.; Jukema, JW.; Johnson, T. ... Barroso, I. (2012). Large-scale association analyses identify new loci influencing glycemic traits and provide insight into the underlying biological pathways. Nature Genetics, 44 (9), 991−1005. DOI: 10.1038/ng.2385.
1.1.
2012
Yang, J; Ferreira, T; Morris, AP; Medland, SE; GIANT, consortium; DIAGRAM, consortium; Madden, PAF; Heath, AC; Martin, NG; Montgomery, GW; Weedon, MN; Loos, RJ; Frayling, TM; McCarthy, MI; Hirschhorn, JN; Goddard, ME; Visscher, PM. (2012). Conditional and joint multiple-SNP analysis of GWAS summary statistics identifies additional variants influencing complex traits. Nature Genetics, 44, 369−375.
1.1.
2012
Palmer, Nicholette D; McDonough, Caitrin W; Hicks, Pamela J; Roh, Bong H; Wing, Maria R; An, S Sandy; Hester, Jessica M; Cooke, Jessica N; Bostrom, Meredith A; Rudock, Megan E; Talbert, Matthew E; Lewis, Joshua P; Ferrara, Assiamira; Lu, Lingyi; Ziegler, Julie T; Sale, Michele M; Divers, Jasmin; Shriner, Daniel; Adeyemo, Adebowale; Rotimi, Charles N ... Sladek, Robert (2012). A genome-wide association search for type 2 diabetes genes in African Americans. PLOS ONE, 7 (1), e29202−e29202.
1.1.
2012
Scerri, Thomas S.; Darki, Fahimeh; Newbury, Dianne F.; Whitehouse, Andrew J. O.; Peyrard-Janvid, Myriam; Matsson, Hans; Ang, Qi W.; Pennell, Craig E.; Ring, Susan; Stein, John; Morris, Andrew P.; Monaco, Anthony P.; Kere, Juha; Talcott, Joel B.; Klingberg, Torkel; Paracchini, Silvia (2012). The Dyslexia Candidate Locus on 2p12 Is Associated with General Cognitive Ability and White Matter Structure. PLoS ONE, 7 (11), ARTN e50321.10.1371/journal.pone.0050321.
1.1.
2012
Nyholt, Dale R.; Low, Siew-Kee; Anderson, Carl A.; Painter, Jodie N.; Uno, Satoko; Morris, Andrew P.; MacGregor, Stuart; Gordon, Scott D.; Henders, Anjali K.; Martin, Nicholas G.; Attia, John; Holliday, Elizabeth G.; McEvoy, Mark; Scott, Rodney J.; Kennedy, Stephen H.; Treloar, Susan A.; Missmer, Stacey A.; Adachi, Sosuke; Tanaka, Kenichi; Nakamura, Yusuke ... Montgomery, Grant W. (2012). Genome-wide association meta-analysis identifies new endometriosis risk loci. Nature Genetics, 44 (12), 1355−1359.10.1038/ng.2445.
1.1.
2012
Ho, Jennifer E.; Mahajan, Anubha; Chen, Ming-Huei; Larson, Martin G.; McCabe, Elizabeth L.; Ghorbani, Anahita; Cheng, Susan; Johnson, Andrew D.; Lindgren, Cecilia M.; Kempf, Tibor; Lind, Lars; Ingelsson, Erik; Vasan, Ramachandran S.; Januzzi, James; Wollert, Kai C.; Morris, Andrew P.; Wang, Thomas J. (2012). Clinical and Genetic Correlates of Growth Differentiation Factor 15 in the Community. Clinical Chemistry, 58 (11), 1582−1591.10.1373/clinchem.2012.190322.
1.1.
2012
Franceschini, Nora; van Rooij, Frank J. A.; Prins, Bram P.; Feitosa, Mary F.; Karakas, Mahir; Eckfeldt, John H.; Folsom, Aaron R.; Kopp, Jeffrey; Vaez, Ahmad; Andrews, Jeanette S.; Baumert, Jens; Boraska, Vesna; Broer, Linda; Hayward, Caroline; Ngwa, Julius S.; Okada, Yukinori; Polasek, Ozren; Westra, Harm-Jan; Wang, Ying A.; Del Greco M, Fabiola ... Morris, Andrew P. (2012). Discovery and Fine Mapping of Serum Protein Loci through Transethnic Meta-analysis. The American Journal of Human Genetics, 91 (4), 744−753.10.1016/j.ajhg.2012.08.021.
1.1.
2012
Voight, Benjamin F.; Kang, Hyun Min; Ding, Jun; Palmer, Cameron D.; Sidore, Carlo; Chines, Peter S.; Burtt, Noel P.; Fuchsberger, Christian; Li, Yanming; Erdmann, Jeanette; Frayling, Timothy M.; Heid, Iris M.; Jackson, Anne U.; Johnson, Toby; Kilpelaeinen, Tuomas O.; Lindgren, Cecilia M.; Morris, Andrew P.; Prokopenko, Inga; Randall, Joshua C.; Saxena, Richa ... Boehnke, Michael (2012). The Metabochip, a Custom Genotyping Array for Genetic Studies of Metabolic, Cardiovascular, and Anthropometric Traits. PLoS Genetics, 8 (8), ARTN e1002793.10.1371/journal.pgen.1002793.
1.1.
2012
Perry, John R. B.; Voight, Benjamin F.; Yengo, Loic; Amin, Najaf; Dupuis, Josee; Ganser, Martha; Grallert, Harald; Navarro, Pau; Li, Man; Qi, Lu; Steinthorsdottir, Valgerdur; Scott, Robert A.; Almgren, Peter; Arking, Dan E.; Aulchenko, Yurii; Balkau, Beverley; Benediktsson, Rafn; Bergman, Richard N.; Boerwinkle, Eric; Bonnycastle, Lori ... Cauchi, Stephane (2012). Stratifying Type 2 Diabetes Cases by BMI Identifies Genetic Risk Variants in LAMA1 and Enrichment for Risk Variants in Lean Compared to Obese Cases. PLoS Genetics, 8 (5), ARTN e1002741.10.1371/journal.pgen.1002741.
1.1.
2012
Asimit, Jennifer L.; Day-Williams, Aaron G.; Morris, Andrew P.; Zeggini, Eleftheria (2012). ARIEL and AMELIA: Testing for an Accumulation of Rare Variants Using Next-Generation Sequencing Data. Human Heredity, 73 (2), 84−94.10.1159/000336982.
1.1.
2012
Orozco, Gisela; Ioannidis, John P. A.; Morris, Andrew; Zeggini, Eleftheria (2012). Sex-specific differences in effect size estimates at established complex trait loci. International Journal of Epidemiology, 41 (5), 1376−1382.10.1093/ije/dys104.
1.1.
2012
Dastani, Z; Hivert, M-F; Timpson, N; Perry, JRB; Yuan, X; Scott, RA; Henneman, P; Heid, IM; Kizer, JR; Lyytikäinen, L-P; et, al. (2012). Novel Loci for Adiponectin Levels and Their Influence on Type 2 Diabetes and Metabolic Traits: A Multi-Ethnic Meta-Analysis of 45,891 Individuals. PLOS Genetics, 8 (3), e1002607−e1002607.
1.1.
2012
Maller, Julian B.; McVean, Gilean; Byrnes, Jake; Vukcevic, Damjan; Palin, Kimmo; Su, Zhan; Howson, Joanna M. M.; Auton, Adam; Myers, Simon; Morris, Andrew; Pirinen, Matti; Brown, Matthew A.; Burton, Paul R.; Caulfield, Mark J.; Compston, Alastair; Farrall, Martin; Hall, Alistair S.; Hattersley, Andrew T.; Hill, Adrian V. S.; Mathew, Christopher G. ... Donnelly, Peter (2012). Bayesian refinement of association signals for 14 loci in 3 common diseases. Nature Genetics, 44 (12), 1294−1301.10.1038/ng.2435.
5.1.
2012
Mägi, R; Morris, AP. (2012). Genome-wide association analysis of rare variants identifies potential novel susceptibility genes for type 1 diabetes and coronary artery disease. ANNALS OF HUMAN GENETICS, 76: European Mathematical Genetics Meeting, Gottingen, GERMANY, APR 12-13, 2012. Wiley-Blackwell, 421−422.
5.1.
2012
Mägi, R; Horikoshi, M; Surakka, I; Wiltshire, S; Sarin, AP; Mahajan, A; Marullo, L; Ferreira, T; Hagg, S; Ried, JS; Winkler, T; Thorleifsson, G; Tsernikova, N; Esko, T; Willenborg, C; Nelson, CP; Beekman, M; Willems, SM; McCarthy, MI; Morris, AP ... Prokopenko, I. (2012). Large-scale Genome-wide Association Meta-analysis Using Imputation from 2188-haplotype 1000 Genomes Reference Panel Identifies Novel Susceptibility Loci for Anthropometric and Glycemic Traits. GENETIC EPIDEMIOLOGY, 36: Annual Meeting of the International-Genetic-Epidemiology-Society (IGES), Stevenson, WA, OCT 18-20, 2012. Wiley-Blackwell, 776−777. (7).
1.1.
2011
Morris, Andrew P. (2011). Transethnic meta-analysis of genomewide association studies. Genetic Epidemiology, 35 (8), 809−822.10.1002/gepi.20630.
1.1.
2011
Bhattacharya, K; McCarthy, MI; Morris, AP. (2011). Rapid testing of gene-gene interactions in genome-wide association studies of binary and quantitative phenotypes. Genetic Epidemiology, 35 (8), 800−808.10.1002/gepi.20629.
1.1.
2011
Chapman, K; Ferreira, T; Morris, A; Asimit, J; Zeggini, E. (2011). Defining the power limits of genome-wide association scan meta-analyses. Genetic Epidemiology, 35 (8), 781−789.10.1002/gepi.20627.
1.1.
2011
Kooner, JS; Saleheen, D; Sim, X; Sehmi, J; Zhang, WH; Frossard, P; Been, LF; Chia, KS; Dimas, AS; Hassanali, N; Jafar, T; Jowett, JBM; Li, XZ; Radha, V; Rees, SD; Takeuchi, F; Young, R; Aung, T; Basit, A; Chidambaram, M ... Chambers, JC. (2011). Genome-wide association study in individuals of South Asian ancestry identifies six new type 2 diabetes susceptibility loci. Nature Genetics, 43 (10), 984−U94.10.1038/ng.921.
1.1.
2011
Min, JL; Taylor, JM; Richards, JB; Watts, T; Pettersson, FH; Broxholme, J; Ahmadi, KR; Surdulescu, GL; Lowy, E; Gieger, C; Newton-Cheh, C; Perola, M; Soranzo, N; Surakka, I; Lindgren, CM; Ragoussis, J; Morris, AP; Cardon, LR; Spector, TD; Zondervan, KT. (2011). The use of genome-wide eQTL associations in lymphoblastoid cell lines to identify novel genetic pathways involved in complex traits. PLoS ONE, 6 (7), e22070.10.1371/journal.pone.0022070.
1.1.
2011
Clarke, GM; Anderson, CA; Pettersson, FH; Cardon, LR; Morris, AP; Zondervan, KT. (2011). Basic statistical analysis in genetic case-control studies. Nature Protocols, 6 (2), 121−133.10.1038/nprot.2010.182.
1.1.
2011
Painter, JN; Anderson, CA; Nyholt, DR; Macgregor, S; Lin, J; Lee, SH; Lambert, A; Zhao, ZZ; Roseman, F; Guo, Q; Gordon, SD; Wallace, L; Henders, AK; Visscher, PM; Kraft, P; Martin, NG; Morris, AP; Treloar, SA; Kennedy, SH; Missmer, SA ... Zondervan, KT. (2011). Genome-wide association study identifies a locus at 7p15.2 associated with endometriosis. Nature Genetics, 43 (1), 51−U69.10.1038/ng.731.
1.1.
2011
Fox, E.R.; Young, J.H.; Li, Y.; Dreisbach, A.W.; Keating, B.J.; Musani, S.K.; Liu, K.; Morrison, A.C.; Ganesh, S.; Kutlar, A.; Ramachandran, V.S.; Polak, J.F.; Fabsitz, R.R.; Dries, D.L.; Farlow, D.N.; Redline, S.; Adeyemo, A.; Hirschorn, J.N.; Sun, Y.V.; Wyatt, S.B. ... Newton-Cheh, C. (2011). Association of genetic variation with systolic and diastolic blood pressure among African Americans: the Candidate Gene Association Resource study. Human Molecular Genetics, 20 (11), 2273−2284.
1.1.
2011
Scerri, Tom S.; Morris, Andrew P.; Buckingham, Lyn-Louise; Newbury, Dianne F.; Miller, Laura L.; Monaco, Anthony P.; Bishop, Dorothy V. M.; Paracchini, Silvia (2011). DCDC2, KIAA0319 and CMIP Are Associated with Reading-Related Traits. Biological Psychiatry, 70 (3), 237−245.10.1016/j.biopsych.2011.02.005.
1.1.
2011
Scerri, Thomas S.; Brandler, William M.; Paracchini, Silvia; Morris, Andrew P.; Ring, Susan M.; Richardson, Alex J.; Talcott, Joel B.; Stein, John; Monaco, Anthony P. (2011). PCSK6 is associated with handedness in individuals with dyslexia. Human Molecular Genetics, 20 (3), 608−614.10.1093/hmg/ddq475.
1.1.
2011
Bell, Jordana T.; Timpson, Nicholas J.; Rayner, N. William; Zeggini, Eleftheria; Frayling, Timothy M.; Hattersley, Andrew T.; Morris, Andrew P.; McCarthy, Mark I. (2011). Genome-Wide Association Scan Allowing for Epistasis in Type 2 Diabetes. Annals of Human Genetics, 75 (1), 10−19.10.1111/j.1469-1809.2010.00629.x.
1.1.
2011
Jafar-Mohammadi, B.; Groves, C. J.; Gjesing, A. P.; Herrera, B. M.; Winckler, W.; Stringham, H. M.; Morris, A. P.; Lauritzen, T.; Doney, A. S. F.; Morris, A. D.; Weedon, M. N.; Swift, A. J.; Kuusisto, J.; Laakso, M.; Altshuler, D.; Hattersley, A. T.; Collins, F. S.; Boehnke, M.; Hansen, T.; Pedersen, O. ... McCarthy, M. I. (2011). A role for coding functional variants in HNF4A in type 2 diabetes susceptibility. Diabetologia, 54 (1), 111−119.10.1007/s00125-010-1916-4.
1.1.
2011
Scerri TS, Paracchini S, Morris A, MacPhie IL, Talcott J, Stein J, Smith SD, Pennington BF, Olson RK, DeFries JC, Monaco AP, Richardson AJ. (2011). Identification of candidate genes for dyslexia susceptibility on chromosome 18. PLoS ONE, 5 (10), e13712.10.1371/journal.pone.0013712.
1.2.
2011
Mägi, R.; Kumar, A.; Morris, AP. (2011). Assessing the impact of missing genotype data in rare variant association analysis. BMC Proceedings, 9 (5), S107−S107.
3.1.
2011
Morris, A.P. (2011). Haplotype methods for population-based association studies. In: “Analysis Of Complex Disease Association Studies”. In: Edited by Zeggini E, Morris AP. (Ed.). Analysis Of Complex Disease Association Studies (117−195).. Elsevier.
6.8.
2011
Voight, Benjamin F.; Scott, Laura J.; Steinthorsdottir, Valgerdur; Morris, Andrew P.; Dina, Christian; Welch, Ryan P.; Zeggini, Eleftheria; Huth, Cornelia; Aulchenko, Yurii S.; Thorleifsson, Gudmar; McCulloch, Laura J.; Ferreira, Teresa; Grallert, Harald; Amin, Najaf; Wu, Guanming; Willer, Cristen J.; Raychaudhuri, Soumya; McCarroll, Steve A.; Langenberg, Claudia; Hofmann, Oliver M. ... McCarthy, Mark I. (2011). Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis (vol 42, pg 579, 2010). Nature Genetics, 42 (4), 388−388. DOI: 10.1038/ng0411-388b.
1.1.
2010
Lawrence, R; Day-Williams, AG; Elliott, KS; Morris, AP; Zeggini, E. (2010). CCRaVAT and QuTie-enabling analysis of rare variants in large-scale case control and quantitative trait association studies. BMC Bioinformatics, 11, No 527.10.1186/1471-2105-11-527.
1.1.
2010
Bowes, J; Lawrence, R; Eyre, S; Panoutsopoulou, K; Orozco, G; Elliott, KS; Ke, X; Morris, AP; UKRAG, Thomson, W; Worthington, J; Barton, A; Zeggini, E. (2010). Rare variation at the TNFAIP3 locus and susceptibility to rheumatoid arthritis. Human Genetics, 128 (6), 627−633.10.1007/s00439-010-0889-1.
1.1.
2010
Thye, T; Vannberg, FO; Wong, SH; Owusu-Dabo, E; Osei, I; Gyapong, J; Sirugo, G; Sisay-Joof, F; Enimil, A; Chinbuah, MA; Floyd, S; Warndorff, DK; Sichali, L; Malema, S; Crampin, AC; Ngwira, B; Teo, YY; Small, K; Rockett, K; Kwiatkowski, D ... Hill, AV. (2010). Genome-wide association analyses identifies a susceptibility locus for tuberculosis on chromosome 18q11.2. Nature Genetics, 42 (9), 739−741.10.1038/ng.639.
1.1.
2010
Craddock, N.; Hurles, ME.; Cardin, N.; Pearson, RD.; Plagnol, V.; Robson, S.; Vukcevic, D.; Barnes, C.; Conrad, DF.; Giannoulatou, E.; Holmes, C.; Marchini, JL.; Stirrups, K.; Tobin, MD.; Wain, LV.; Yau, C.; Aerts, J.; Ahmad, T.; Andrews, TD.; Arbury, H. ... Donnelly, P (2010). Genome-wide association study of CNVs in 16,000 cases of eight common diseases and 3,000 shared controls. Nature, 464 (7289), 713−720.10.1038/nature08979.
1.1.
2010
Zhuang, JJ; Zondervan, K; Nyberg, F; Harbron, C; Jawaid, A; Cardon, LR; Barratt, BJ; Morris, AP. (2010). Optimizing the power of genome-wide association studies by using publicly available reference samples to expand the control group. Genetic Epidemiology, 34 (4), 319−326.10.1002/gepi.20482.
1.1.
2010
Clarke, GM; Morris, AP. (2010). A comparison of sample size and power in case-only association studies of gene-environment interaction. American Journal of Epidemiology, 171 (4), 498−505.10.1093/aje/kwp398.
1.1.
2010
Morris, AP; Lindgren, CM; Zeggini, E; Timpson, NJ; Frayling, TM; Hattersley, AT; McCarthy, MI. (2010). A powerful approach to sub-phenotype analysis in population-based genetic association studies. Genetic Epidemiology, 34 (4), 335−343.10.1002/gepi.20486.
1.1.
2010
Fawcett, KA; Wheeler, E; Morris, AP; Ricketts, SL; Hallmans, G; Rolandsson, O; Daly, A; Wasson, J; Permutt, A; Hattersley, AT; Glaser, B; Franks, PW; McCarthy, MI; Wareham, NJ; Sandhu, MS; Barroso, I. (2010). Detailed investigation of the role of common and low-frequency WFS1 variants in type 2 diabetes risk. Diabetes, 59 (3), 741−746.10.2337/db09-0920.
1.1.
2010
Morris, AP; Zeggini, E. (2010). An evaluation of statistical approaches to rare variant analysis in genetic association studies. Genetic Epidemiology, 34 (2), 188−193.10.1002/gepi.20450.
1.1.
2010
Mägi, Reedik; Lindgren, Cecilia M.; Morris, Andrew P. (2010). Meta-analysis of sex-specific genome-wide association studies. Genetic Epidemiology, 34 (8), 846−853.10.1002/gepi.20540.
1.1.
2010
Lango Allen, Hana; Estrada, Karol; Lettre, Guillaume; Berndt, Sonja I; Weedon, Michael N; Rivadeneira, Fernando; Willer, Cristen J; Jackson, Anne U; Vedantam, Sailaja; Raychaudhuri, Soumya; Ferreira, Teresa; Wood, Andrew R; Weyant, Robert J; Segre, Ayellet V; Speliotes, Elizabeth K; Wheeler, Eleanor; Soranzo, Nicole; Park, Ju-Hyun; Yang, Jian; Gudbjartsson, Daniel ... Hirschhorn, Joel N (2010). Hundreds of variants clustered in genomic loci and biological pathways affect human height. Nature, 467 (7317), 832−838.
1.1.
2010
Dupuis, J.; Langenberg, C.; Prokopenko, I.; Saxena, R.; Soranzo, N.; Jackson, A.U.; Wheeler, E.; Glazer, N.L.; Bouatia-Naji, N.; Gloyn, A.L.; Lindgren, C.M.; Mägi, R.; Morris, A.P.; Randall, J.; Johnson, T.; Elliott, P.; Rybin, D.; Thorleifsson, G.; Steinthorsdottir, V.; Henneman, P. ... Mitchell, B.D (2010). New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk. Nature Genetics, 42 (2), 105−116.10.1038/ng.520.
1.1.
2010
Mägi, R; Morris, AP. (2010). GWAMA: software for genome-wide association meta-analysis. BMC Bioinformatics, 11 (288), 288.10.1186/1471-2105-11-288.
1.1.
2010
Anderson, Carl A.; Pettersson, Fredrik H.; Clarke, Geraldine M.; Cardon, Lon R.; Morris, Andrew P.; Zondervan, Krina T. (2010). Data quality control in genetic case-control association studies. Nature Protocols, 5 (9), 1564−1573.10.1038/nprot.2010.116.
1.1.
2010
Speliotes, E.K.; Willer, C.J.; Berndt, S.I.; Monda, K.L.; Thorleifsson, G.; Jackson, A.U.; Allen, H.L.; Lindgren, C.M.; Luan, J.; Mägi, R.; Randall, J.C.; Vedantam, S.; Winkler, T.W.; Workalemahu, T.; Heid, I.M.; Qi, L.; Steinthorsdottir, V.; Weedon, M.N.; Wheeler, E.; Wood, A.R. ... Hayward, C. (2010). Genome-wide association study of 249,796 individuals reveals eighteen loci associated with body mass index. Nature Genetics, 11, 937−948. DOI: 10.1038/ng.686.
1.1.
2010
Heid, Iris M; Jackson, Anne U; Randall, Joshua C; Winkler, Thomas W; Qi, Lu; Steinthorsdottir, Valgerdur; Thorleifsson, Gudmar; Zillikens, M Carola; Speliotes, Elizabeth K; Mägi, Reedik; Workalemahu, Tsegaselassie; White, Charles C; Bouatia-Naji, Nabila; Harris, Tamara B; Berndt, Sonja I; Ingelsson, Erik; Willer, Cristen J; Weedon, Michael N; Luan, Jian'an; Vedantam, Sailaja ... Lindgren, Cecilia M (2010). Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution. Nature Genetics, 42 (11), 949−960. DOI: 10.1038/ng.685.
1.1.
2010
Cho EY, Jang Y, Shin ES, Jang HY, Yoo Y-K, Kim S, Jang JH, Lee JY, Yun MH, Park MY, Chae JS, Lim JW, Shin DJ, Park S, Lee JH, Han BG, Rae KH, Cardon LR, Morris AP, Lee JE, Clarke GM. (2010). Genome-wide association analysis and replication of coronary artery disease in South Korea suggests a causal variant common to diverse populations. Heart Asia, 2 (1), 104−108. DOI: 10.1136/ha.2009.001370.
1.1.
2010
Tönjes A, Zeggini E, Kovacs P, Böttcher Y, Schleinitz D, Dietrich K, Morris AP, Enigk B, Rayner NW, Koriath M, Eszlinger M, Kemppinen A, Prokopenko I, Hoffmann K, Teupser D, Thiery J, Krohn K, McCarthy MI, Stumvoll M. (2010). Association of FTO variants with BMI and fat mass in the self-contained population of Sorbs in Germany. European Journal of Human Genetics, 18 (1), 104−110. DOI: 10.1038/ejhg.2009.107.
5.1.
2010
Mägi, R; Morris, AP. (2010). GRANVIL: Rare Variant Analysis of Genome-Wide Association Studies. Genetic Epidemiology, 34: 19th Annual Meeting of the International-Genetic-Epidemiology-Society, Boston, MA, OCT 10-12, 2010. Wiley-Blackwell, 926−926. (8).
1.1.
2009
Lindgren, CM; Heid, IM; Randall, JC; Steinthorsdottir, V; Qi, L; Speliotes, EK; Thorleifsson, G; Willer, CJ; Herrera, BM; Jackson, AU; Lim, N; Scheet, P; Soranzo, N; Amin, N; Aulchenko, YS; Chambers, JC; Drong, A; Luan, JA; Lyon, HN; Rivadeneira, F ... McCarthy, M (2009). Genome-wide association scan meta-analysis identifies three loci influencing adiposity and fat distribution. PLoS Genetics, 5 (6), No e1000508. DOI: 10.1371/journal.pgen.1000508.
1.1.
2009
Jallow, M; Teo, YY; Small, K; Rockett, KA; Deloukas, P; Clark, TG; Kivinen, K; Bojang, KA; Conway, DJ; Pinder, M; Sirugo, G; Sisay-Joof, F; Usen, S; Auburn, S; Bumpstead, SJ; Campino, S; Coffey, A; Dunham, A; Fry, AE; Green, A ... Kwiatkowski, DP (2009). Genome-wide and fine-resolution association analysis of malaria in West Africa. Nature Genetics, 41 (6), 657−665. DOI: 10.1038/ng.388.
1.1.
2009
Maestrini, E; Pagnamenta, AT; Lamb, JA; Bacchelli, E; Sykes, NH; Sousa, I; Toma, C; Barnby, G; Butler, H; Winchester, L; Scerri, TS; Minopoli, F; Reichert, J; Cai, G; Buxbaum, JD; Korvatska, O; Schellenberg, GD; Dawson, G; Bildt, AD; Minderaa, RB ... Monaco, AP. (2009). High-density SNP association study and copy number variation analysis of the AUTS1 and AUTS5 loci implicate the IMMP2L-DOCK4 gene region in autism susceptibility. Molecular Psychiatry, 15 (9), 954−968. DOI: 10.1038/mp.2009.34.
1.1.
2009
Pettersson, FH; Anderson, CA; Clarke, GM; Barrett, JC; Cardon, LR; Morris, AP; Zondervan, KT. (2009). Marker selection for genetic case-control association studies. Nature Protocols, 4 (5), 743−752. DOI: 10.1038/nprot.2009.38.
1.1.
2009
Cooney, R; Cummings, JR; Pathan, S; Beckly, J; Geremia, A; Hancock, L; Guo, C; Morris, A; Jewell, DP. (2009). Association between genetic variants in myosin IXB and Crohn’s disease. Inflammatory Bowel Diseases, 15 (7), 1014−1021. DOI: 10.1002/ibd.20885.
1.1.
2009
Diakite, M; Clark, TG; Auburn, S; Campino, S; Fry, AE; Green, A; Morris, AP; Richardson, A; Jallow, M; Sisay-Joof, F; Pinder, M; Kwiatkowski, DP; Rockett, KA. (2009). A genetic association study in the Gambia using tagging polymorphisms in the major histocompatibility complex class III region implicates a HLA-B associated transcript 2 polymorphism in severe malaria susceptibility. Human Genetics, 125 (1), 105−109. DOI: 10.1007/s00439-008-0597-2.
1.1.
2009
Carpenter, D; Morris, A; Robinson, RL; Booms, P; Iles, D; Halsall, PJ; Steele, D; Hopkins, PM; Shaw, MA. (2009). Analysis of RYR1 haplotype profile in patients with malignant hyperthermia. Annals of Human Genetics, 73, 10−18. DOI: 10.1111/j.1469-1809.2008.00482.x.
1.1.
2009
Zhuang JJ, Morris AP. (2009). Assessment of sex-specific effects in a genome-wide association study of rheumatoid arthritis. BMC Proceedings, 3 (S90), 1−4. DOI: 10.1186/1753-6561-3-S7-S90.
1.1.
2009
Clarke, Geraldine M; Pettersson, Fredrik H; Morris, Andrew P (2009). A comparison of case-only designs for detecting gene × gene interaction in rheumatoid arthritis using genome-wide case-control data in Genetic Analysis Workshop 16. BMC Proceedings, 3 (S7), 1−4. DOI: 10.1186/1753-6561-3-S7-S73.
1.1.
2009
Morris, Andrew P; Zeggini, Eleftheria; Lindgren, Cecilia M (2009). Identification of novel putative rheumatoid arthritis susceptibility genes via analysis of rare variants. BMC Proceedings, 3 (S7), 1−5. DOI: 10.1186/1753-6561-3-S7-S131.
1.1.
2009
Carpenter, Danielle; Ringrose, Christopher; Leo, Vincenzo; Morris, Andrew; Robinson, Rachel L.; Halsall, P. Jane; Hopkins, Philip M.; Shaw, Marie-Anne (2009). The role of CACNA1S in predisposition to malignant hyperthermia. BMC Medical Genetics, 10, ARTN 104. DOI: 10.1186/1471-2350-10-104.
1.1.
2009
Pathan, S.; Gowdy, R. E.; Cooney, R.; Beckly, J. B.; Hancock, L.; Guo, C.; Barrett, J. C.; Morris, A.; Jewell, D. P. (2009). Confirmation of the novel association at the BTNL2 locus with ulcerative colitis. Tissue Antigens, 74 (4), 322−329. DOI: 10.1111/j.1399-0039.2009.01314.x.
1.1.
2008
Paracchini, Silvia; Steer, Colin D.; Buckingham, Lyn-Louise; Morris, Andrew P.; Ring, Susan; Scerri, Thomas; Stein, John; Pembrey, Marcus E.; Ragoussis, Jiannis; Golding, Jean; Monaco, Anthony P. (2008). Association of the KIAA0319 Dyslexia Susceptibility Gene With Reading Skills in the General Population. American Journal of Psychiatry, 165 (12), 1576−1584. DOI: 10.1176/appi.ajp.2008.07121872.
1.1.
2008
Orton, SM; Morris, AP; Herrera, BM; Ramagopalan, SV; Lincoln, MR; Chao, MJ; Vieth, R; Sadovnick, AD; Ebers, GC. (2008). Evidence for genetic regulation of vitamin D status in twins with multiple sclerosis. The American Journal of Clinical Nutrition, 88 (2), 441−447.
1.1.
2008
Anderson, CA; Pettersson, FH; Barrett, JC; Zhuang, JJ; Ragoussis, J; Cardon, LR; Morris, AP. (2008). Evaluating the effects of imputation on the power, coverage and cost efficiency of genome-wide SNP platforms. The American Journal of Human Genetics, 83 (1), 112−119. DOI: 10.1016/j.ajhg.2008.06.008.
1.1.
2008
Pettersson, F; Morris, AP; Barnes, MR; Cardon, LR. (2008). Goldsurfer2 (Gs2): a comprehensive tool for the analysis and visualisation of genome-wide association studies. BMC Bioinformatics, 9, No 138. DOI: 10.1186/1471-2105-9-138.
1.1.
2008
Beckly, John B.; Hancock, Laura; Geremia, Alessandro; Cummings, J. R. Fraser; Morris, Andrew; Cooney, Rachel; Pathan, Saad; Guo, Changcun; Jewell, Derek P. (2008). Two-stage candidate gene study of chromosome 3p demonstrates an association between nonsynonymous variants in the MST1R gene and Crohn's disease. Inflammatory Bowel Diseases, 14 (4), 500−507. DOI: 10.1002/ibd.20365.
1.1.
2008
Wiltshire, Steven; Morris, Andrew P.; Zeggini, Eleftheria (2008). Examining the statistical properties of fine-scale mapping in large-scale association studies. Genetic Epidemiology, 32 (3), 204−214. DOI: 10.1002/gepi.20295.
1.1.
2007
Newport, M; Sirugo, G; Lyons, E; Vannberg, F; Hill, AVS; Bradbury, LA; Farrar, C; Pointon, JJ; Wordsworth, P; Brown, MA; Franklyn, JA; Heward, JM; Simmonds, MJ; Gough, SC; Seal, S; Stratton, MR; Rahman, N; Ban, M; Goris, A; Sawcer, SJ ... Brown, MA (2007). Association scan of 14,500 nonsynonymous SNPs in four diseases identifies autoimmunity variants. Nature Genetics, 39 (11), 1329−1337. DOI: 10.1038/ng.2007.17.
1.1.
2007
Frazer, KA; Ballinger, DG; Cox, DR; Hinds, DA; Stuve, LL; Gibbs, RA; Belmont, JW; Boudreau, A; Hardenbol, P; Leal, SM; Pasternak, S; Wheeler, DA; Willis, TD; Yu, FL; Yang, HM; Zeng, CQ; Gao, Y; Hu, HR; Hu, WT; Li, CH ... Skol, A (2007). A second generation human haplotype map of over 3.1 million SNPs. Nature, 449 (7164), 851−U3. DOI: 10.1038/nature06258.
1.1.
2007
Clarke, GM; Carter, KW; Palmer, LJ; Morris, AP; Cardon, LR. (2007). Fine mapping versus replication in whole-genome association studies. American Journal of Human Genetics, 81 (5), 995−1005.
1.1.
2007
Dunstan, S.J.; Nguyen, T.H.; Rockett, K.; Forton, J.; Morris, A.P.; Diakite, M.; Mai, N.L.; Le, T.P.; House, D.; Parry, C.M.; Ha, V.; Nguyen, T.H.; Dougan, G.; Tran, T.H.; Kwiatowski, D.; Farrar, J.J. (2007). A TNF region haplotype offers protection from typhoid fever in Vietnamese patients. Human Genetics, 122 (1), 51−61. DOI: 10.1007/s00439-007-0372-9.
1.1.
2007
Burton, PR; Clayton, DG; Cardon, LR; Craddock, N; Deloukas, P; Duncanson, A; Kwiatkowski, DP; McCarthy, MI; Ouwehand, WH; Samani, NJ; Todd, JA; Donnelly, P; Barrett, JC; Davison, D; Easton, D; Evans, D; Leung, HT; Marchini, JL; Morris, AP; Spencer, CCA ... Worthington, J (2007). Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls. Nature, 447 (7145), 661−678. DOI: 10.1038/nature05911.
1.1.
2007
Zeggini, E.; Weedon, M.N.; Lindgren, C.M.; Frayling, T.M.; Elliott, K.S.; Lango, H.; Timpson, N.J.; Perry, J.R.; Rayner, N.W.; Freathy, R.M.; Barrett, J.C.; Shields, B.; Morris, A.P.; Ellard, S.; Groves, C.J.; Harries, L.W.; Marchini, J.L.; Owen, K.R.; Knight, B.; Cardon, L.R. ... Hattersley, A.T. (2007). Replication of genome-wide association signals in UK samples reveals risk loci for type 2 diabetes. Science, 316 (5829), 1336−1341. DOI: 10.1126/science.1142364.
1.1.
2007
Sabeti, Pardis C.; Varilly, Patrick; Fry, Ben; Lohmueller, Jason; Hostetter, Elizabeth; Cotsapas, Chris; Xie, Xiaohui; Byrne, Elizabeth H.; McCarroll, Steven A.; Gaudet, Rachelle; Schaffner, Stephen F.; Lander, Eric S. et al. (2007). Genome-wide detection and characterization of positive selection in human populations. Nature, 449 (7164), 913−920. DOI: 10.1038/nature06250.
1.1.
2007
Ramagopalan, Sreeram V.; Morris, Andrew P.; Dyment, David A.; Herrera, Blanca M.; DeLuca, Gabriele C.; Lincoln, Matthew R.; Orton, Sarah M.; Chao, Michael J.; Sadovnick, A. Dessa; Ebers, George C. (2007). The inheritance of resistance alleles in multiple sclerosis. PLoS Genetics, 3 (9), ARTN e150−1613. DOI: 10.1371/journal.pgen.0030150.
3.1.
2007
Morris, A.P. (2007). Coalescent methods for fine-scale disease-gene mapping. In: Linkage Disequilibrium and Association Mapping (123−140). . Springer. (Methods in Molecular Biology). DOI: 10.1007/978-1-59745-389-9_9.
3.1.
2007
Morris, A.P. (2007). Haplotype estimation. In: “Statistical Genetics: Gene Mapping Through Linkage And Association”. In: Edited by Neale B, Ferreira MAR, Medland SE (Ed.). Statistical Genetics: Gene Mapping Through Linkage And Association (395−418).. Taylor & Francis.
1.1.
2006
Evans, David M.; Marchini, Jonathan; Morris, Andrew P.; Cardon, Lon R. (2006). Two-stage two-locus models in genome-wide association. PLoS Genetics, 2 (9), ARTN e157−1432. DOI: 10.1371/journal.pgen.0020157.
1.1.
2006
Morris, Andrew P. (2006). A flexible Bayesian framework for modeling haplotype association with disease, allowing for dominance effects of the underlying causative variants. The American Journal of Human Genetics, 79 (4), 679−694. DOI: 10.1086/508264.
1.1.
2006
Evans, D. M.; Morris, A. P.; Cardon, L. R.; Sham, P. C. (2006). A note on the power to detect transmission distortion in parent-child trios via the transmission disequilibrium test. Behavior Genetics, 36 (6), 947−950. DOI: 10.1007/s10519-006-9087-2.
1.1.
2005
Durrant, C; Morris, AP (2005). Linkage disequilibrium mapping via cladistic analysis of phase-unknown genotypes and inferred haplotypes in the Genetic Analysis Workshop 14 simulated data. BMC Genetics, 6, ARTN S100. DOI: 10.1186/1471-2156-6-S1-S100.
1.1.
2005
Farrall, M; Morris, AP (2005). Gearing up for genome-wide gene-association studies. Human Molecular Genetics, 14, R157−R162. DOI: 10.1093/hmg/ddi273.
1.1.
2005
Zeggini, E; Rayner, W; Morris, AP; Hattersley, AT; Walker, M; Hitman, GA; Deloukas, P; Cardon, LR; McCarthy, MI (2005). An evaluation of HapMap sample size and tagging SNP performance in large-scale empirical and simulated data sets. Nature Genetics, 37 (12), 1320−1322. DOI: 10.1038/ng1670.
1.1.
2005
Lawrence, R; Evans, DM; Morris, AP; Ke, XY; Hunt, S; Paolucci, M; Ragoussis, J; Deloukas, P; Bentley, D; Cardon, LR (2005). Genetically indistinguishable SNPs and their influence on inferring the location of disease-associated variants. Genome Research, 15 (11), 1503−1510. DOI: 10.1101/gr.4217605.
1.1.
2005
Altshuler, D; Brooks, LD; Chakravarti, A; Collins, FS; Daly, MJ; Donnelly, P; Gibbs, RA; Belmont, JW; Boudreau, A; Leal, SM; Hardenbol, P; Pasternak, S; Wheeler, DA; Willis, TD; Yu, FL; Yang, HM; Zeng, CQ; Gao, Y; Hu, HR; Hu, WT ... Stewart, J (2005). A haplotype map of the human genome. Nature, 437 (7063), 1299−1320. DOI: 10.1038/nature04226.
1.1.
2005
Morris, AP (2005). Direct analysis of unphased SNP genotype data in population-based association studies via Bayesian partition modelling of haplotypes. Genetic Epidemiology, 29 (2), 91−107. DOI: 10.1002/gepi.20080.
1.1.
2005
Barnby, G; Abbott, A; Sykes, N; Morris, A; Weeks, DE; Mott, R; Lamb, J; Bailey, AJ; Monaco, AP (2005). Candidate-gene screening and association analysis at the autism-susceptibility locus on chromosome 16p: Evidence of association at GRIN2A and ABAT. The American Journal of Human Genetics, 76 (6), 950−966. DOI: 10.1086/430454.
1.1.
2005
Wiltshire, S; Morris, AP; McCarthy, MI; Cardon, LR (2005). How useful is the fine-scale mapping of complex trait linkage peaks? Evaluating the impact of additional microsatellite genotyping on the posterior probability of linkage. Genetic Epidemiology, 28 (1), 1−10. DOI: 10.1002/gepi.20023.
1.1.
2004
Evans, DM; Cardon, LR; Morris, AP (2004). Genotype prediction using a dense map of SNPs. Genetic Epidemiology, 27 (4), 375−384. DOI: 10.1002/gepi.20045.
1.1.
2004
Yalcin, B; Willis-Owen, SAG; Fullerton, J; Meesaq, A; Deacon, RM; Rawlins, JNP; Copley, RR; Morris, AP; Flint, J; Mott, R (2004). Genetic dissection of a behavioral quantitative trait locus shows that Rgs2 modulates anxiety in mice. Nature Genetics, 36 (11), 1197−1202. DOI: 10.1038/ng1450.
1.1.
2004
Ke, XY; Hunt, S; Tapper, W; Lawrence, R; Stavrides, G; Ghori, J; Whittaker, P; Collins, A; Morris, AP; Bentley, D; Cardon, LR; Deloukas, P (2004). The impact of SNP density on fine-scale patterns of linkage disequilibrium. Human Molecular Genetics, 13 (6), 577−588. DOI: 10.1093/hmg/ddh060.
1.1.
2004
Ke, XY; Durrant, C; Morris, AP; Hunt, S; Bentley, DR; Deloukas, P; Cardon, LR (2004). Efficiency and consistency of haplotype tagging of dense SNP maps in multiple samples. Human Molecular Genetics, 13 (21), 2557−2565. DOI: 10.1093/hmg/ddh294.
1.1.
2004
Foster, MW (2004). Integrating ethics and science in the international HapMap project. Nature Reviews Genetics, 5 (6), 467−475. DOI: 10.1038/nrg1351.
1.1.
2004
Durrant, C; Zondervan, KT; Cardon, LR; Hunt, S; Deloukas, P; Morris, AP (2004). Linkage disequilibrium mapping via cladistic analysis of single-nucleotide polymorphism haplotypes. The American Journal of Human Genetics, 75 (1), 35−43. DOI: 10.1086/422174.
1.1.
2004
Morris, AP; Whittaker, JC; Balding, DJ (2004). Little loss of information due to unknown phase for fine-scale linkage-disequilibrium mapping with single-nucleotide-polymorphism genotype data. The American Journal of Human Genetics, 74 (5), 945−953. DOI: 10.1086/420773.
1.1.
2003
Gibbs, RA; Belmont, JW; Hardenbol, P; Willis, TD; Yu, FL; Yang, HM; Ch'ang, LY; Huang, W; Liu, B; Shen, Y; Tam, PKH; Tsui, LC; Waye, MMY; Wong, JTF; Zeng, CQ; Zhang, QR; Chee, MS; Galver, LM; Kruglyak, S; Murray, SS ... Tanaka, T (2003). The International HapMap Project. Nature, 426 (6968), 789−796. DOI: 10.1038/nature02168.
1.1.
2003
Anagnostopoulos, T; Morris, AP; Ayres, KL; Giannelli, F; Green, PM (2003). DNA variation in a 13-Mb region including the F9gene: inferring the genealogical history and causal role of a hemophilia B mutation (IVS 5+13 A -> G). Journal of Thrombosis and Haemostasis, 1 (12), 2609−2614. DOI: 10.1111/j.1538-7836.2003.00514.x.
1.1.
2003
Morris, AP; Whittaker, JC; Xu, CF; Hosking, LK; Balding, DJ (2003). Multipoint linkage-disequilibrium mapping narrows location interval and identifies mutation heterogeneity. Proceedings of the National Academy of Sciences, 100 (23), 13442−13446. DOI: 10.1073/pnas.2235031100.
1.1.
2003
Morris, A; Pedder, A; Ayres, K (2003). Linkage disequilibrium assessment via log-linear modeling of SNP haplotype frequencies. Genetic Epidemiology, 25 (2), 106−114. DOI: 10.1002/gepi.10254.
1.1.
2003
Phillips, MS; Lawrence, R; Sachidanandam, R; Morris, AP; Balding, DJ; Donaldson, MA; Studebaker, JF; Ankener, WM; Alfisi, SV; Kuo, FS; Camisa, AL; Pazorov, V; Scott, KE; Carey, BJ; Faith, J; Katari, G; Bhatti, HA; Cyr, JM; Derohannessian, V; Elosua, C ... Cardon, LR (2003). Chromosome-wide distribution of haplotype blocks and the role of recombination hot spots. Nature Genetics, 33 (3), 382−387. DOI: 10.1038/ng1100.
1.1.
2002
Morris, AP; Whittaker, JC; Balding, DJ (2002). Fine-scale mapping of disease loci via shattered coalescent modeling of genealogies. The American Journal of Human Genetics, 70 (3), 686−707. DOI: 10.1086/339271.
1.1.
2000
Morris, AP; Whittaker, JC; Balding, DJ (2000). Bayesian fine-scale mapping of disease loci, by hidden Markov models. The American Journal of Human Genetics, 67 (1), 155−169. DOI: 10.1086/302956.
1.1.
2000
Morris, AP; Whittaker, JC (2000). Fine scale association mapping of disease loci using simplex families. Annals of Human Genetics, 64, 223−237. DOI: 10.1046/j.1469-1809.2000.6430223.x.
1.1.
2000
Whittaker, JC; Denham, MC; Morris, AP (2000). The problems of using the transmission/disequilibrium test to infer tight linkage. The American Journal of Human Genetics, 67 (2), 523−526. DOI: 10.1086/303007.
1.1.
1999
Morris AP, Whittaker JC. (1999). Generalisation of the extended transmission disequilibrium test to two unlinked disease loci. Genetic Epidemiology, 17 (S661), S661−S666.
1.1.
1998
Whittaker, J.C.; Morris, A.P.; Curnow, R.N. (1998). Using information from both parents when testing for association between marker and disease loci. Genetic Epidemiology, 15 (2), 193−200. DOI: 10.1002/(SICI)1098-2272(1998)15:2<193::AID-GEPI7>3.0.CO;2-7.
1.1.
1998
Curnow, RN; Morris, AP (1998). Pooling DNA in the identification of parents. Heredity, 80, 101−109. DOI: 10.1038/sj.hdy.6882420.
1.1.
1997
Morris AP, Curnow RN, Whittaker JC. (1997). Randomisation tests of disease-marker associations. Annals of Human Genetics, 61, 49−60. DOI: 10.1046/j.1469-1809.1997.6110047.x.
1.1.
1997
Morris, AP; Whittaker, JC; Curnow, RN (1997). A likelihood ratio test for detecting patterns of disease-marker association. Annals of Human Genetics, 61, 335−350. DOI: 10.1046/j.1469-1809.1997.6140335.x.
1.1.
1995
MORRIS, A; MORTON, NE; COLLINS, A; LAWRENCE, S; MACPHERSON, JN (1995). EVOLUTIONARY DYNAMICS OF THE FMR1 LOCUS. Annals of Human Genetics, 59, 283−289. DOI: 10.1111/j.1469-1809.1995.tb00748.x.
1.1.
1995
MORRIS, A; MORTON, NE; COLLINS, A; MACPHERSON, J; NELSON, D; SHERMAN, S (1995). AN N-ALLELE MODEL FOR PROGRESSIVE AMPLIFICATION IN THE FMR1 LOCUS. Proceedings of the National Academy of Sciences, 92 (11), 4833−4837. DOI: 10.1073/pnas.92.11.4833.
13.03.2020

Andrew Paul Morris

https://www.etis.ee/CV/Andrew Paul_Morris/eng
17.05.1973
+44 (0)161 306 8732
andrew.morris-5@manchester.ac.uk

Career

Institutions and positions
01.06.2019–...   
University of Manchester, Professor of Statistical Genetics (1,00)
01.05.2010–...   
University of Tartu, Estonian Genome Center, Professor (0,05)
01.01.2014–31.05.2019   
University of Liverpool, Professor (1,00)
01.07.2007–30.06.2017   
University of Liverpool, Wellcome Trust Senior Research Fellow (1,00)
01.01.2005–31.12.2007   
Wellcome Trust Centre for Human Genetics, University of Oxford. Funded by The Leverhulme Trust. Leverhulme Early Career Fellow
01.01.2001–31.12.2007   
Wellcome Trust Centre for Human Genetics, University of Oxford. Funded by The Wellcome Trust, Research Scientist
01.01.1998–31.12.2000   
Department of Applied Statistics, University of Reading. Funded by Pfizer Central Research Limited, UK. Research Fellow
01.01.1994–31.12.1994   
Human Genetics Research Division, University of Southampton. Research Assistant
 
 
Education
1995–1998   
University of Reading. PhD Applied Statistics
1994–1995   
University of Reading. MSc Biometry: Distinction
1991–1994   
University of Reading. BSc (Hons) Statistics: First Class
 
 
R&D related managerial and administrative work
2020−...   
MRC Non-clinical Career Development Panel
2019−...   
Associate Editor, Frontiers in Genetics
2017−...   
Clinical Practice Research Datalink (CPRD), Independent Scientific Advisory Committee Professional Member
2015−...   
Member of the editorial board of eLife Science
2014−...   
Section Editor, Current Diabetes Reports
2010−...   
Member of the editorial board of Genetic Epidemiology.
2010−...   
Course organiser for the Wellcome Trust Advanced Course "Design and Analysis of Genetic-based Association Studies" with Prof. Heather Cordell (University of Newcastle) and Dr. Jonathan Marchini (University of Oxford).
2018−2018   
Past President, International Genetic Epidemiology Society
2017−2017   
President, International Genetic Epidemiology Society
2016−2016   
President Elect, International Genetic Epidemiology Society
2014−2018   
Member of the editorial board of Scientific Reports
2012−2018   
Member of the board of directors of the International Genetic Epidemiology Society
2011−2011   
Co-editor "Analysis of Complex Disease Association Studies" with Dr. Eleftheria Zeggini (Wellcome Trust Sanger Institute)
2010−2010   
Course Director for Wellcome Trust Doctoral Programme in Genomic Medicine and Statistics at the University of Oxford.
2010−2010   
Host and organiser of the 2010 European Mathematical Genetics Meeting at the University of Oxford

Qualifications

Academic degrees
Andrew Paul Morris, Doctor's Degree, 1998, (sup) Robert Curnow; John Whittaker, Linkage and association methods for locating disease genes, University of Reading.
 
 
Honours & awards
2010, Andrew Paul Morris, Best Paper in Genetic Epidemiology 2010: “A powerful approach to sub-phenotype analysis in population-based genetic association studies”.
 
 
Fields of research
ETIS CLASSIFICATION: 1. Biosciences and Environment; 1.3. Genetics; CERCS CLASSIFICATION: B220 Genetics, cytogenetics
 
 

Projects in progress

Completed projects

Dissertations under supervision

Supervised dissertations

Publications

Category
Year
Publication
 
1.1.
2020
Zhu, Bangfu; Mak, Jennifer C. H.; Morris, Andrew P.; Marson, Anthony G.; Barclay, Jeff W.; Sills, Graeme J.; Morgan, Alan (2020). Functional analysis of epilepsy-associated variants in STXBP1/Munc18-1 using humanized Caenorhabditis elegans. Epilepsia. DOI: 10.1111/epi.16464.
1.1.
2020
Thompson, Andrew; Cook, James; Choquet, Helene; Jorgenson, Eric; Yin, Jie; Kinnunen, Tarja; Barclay, Jeff; Morris, Andrew P.; Pirmohamed, Munir (2020). Functional validity, role, and implications of heavy alcohol consumption genetic loci. Science Advances, 6 (3), ARTN eaay5034. DOI: 10.1126/sciadv.aay5034.
1.1.
2020
Shah, Sonia; Henry, Albert; Roselli, Carolina; Lin, Honghuang; Sveinbjornsson, Gardar; Fatemifar, Ghazaleh; Hedman, Asa K.; Wilk, Jemma B.; Morley, Michael P.; Chaffin, Mark D.; Helgadottir, Anna; Verweij, Niek; Dehghan, Abbas; Almgren, Peter; Andersson, Charlotte; Aragam, Krishna G.; Arnlov, Johan; Backman, Joshua D.; Biggs, Mary L.; Bloom, Heather L. ... Ye, Bin (2020). Genome-wide association and Mendelian randomisation analysis provide insights into the pathogenesis of heart failure. Nature Communications, 11 (1), ARTN 163. DOI: 10.1038/s41467-019-13690-5.
1.1.
2020
Turner, Richard M.; Fontana, Vanessa; FitzGerald, Richard; Morris, Andrew P.; Pirmohamed, Munir (2020). Investigating the clinical factors and comedications associated with circulating levels of atorvastatin and its major metabolites in secondary prevention. British Journal of Clinical Pharmacology, 86 (1), 62−74. DOI: 10.1111/bcp.14133.
1.1.
2019
de Vries, Paul S.; Brown, Michael R.; Bentley, Amy R.; Sung, Yun J.; Winkler, Thomas W.; Ntalla, Ioanna; Schwander, Karen; Kraja, Aldi T.; Guo, Xiuqing; Franceschini, Nora; Cheng, Ching-Yu; Sim, Xueling; Vojinovic, Dina; Huffman, Jennifer E.; Musani, Solomon K.; Li, Changwei; Feitosa, Mary F.; Richard, Melissa A.; Noordam, Raymond; Aschard, Hugues ... Morrison, Alanna C. (2019). Multiancestry Genome-Wide Association Study of Lipid Levels Incorporating Gene-Alcohol Interactions. American Journal of Epidemiology, 188 (6), 1033−1054. DOI: 10.1093/aje/kwz005.
1.1.
2019
Bentley, Amy R; Sung, Yun J; Brown, Michael R; Winkler, Thomas W; Kraja, Aldi T; Ntalla, Ioanna; Schwander, Karen; Chasman, Daniel I; Lim, Elise; Deng, Xuan; Guo, Xiuqing; Liu, Jingmin; Lu, Yingchang; Cheng, Ching-Yu; Sim, Xueling; Vojinovic, Dina; Huffman, Jennifer E; Musani, Solomon K; Li, Changwei; Feitosa, Mary F ... Cupples, L Adrienne (2019). Multi-ancestry genome-wide gene-smoking interaction study of 387,272 individuals identifies new loci associated with serum lipids. Nature Genetics, 51 (4), 636−648. DOI: 10.1038/s41588-019-0378-y.
1.1.
2019
Kilpelainen, Tuomas O.; Bentley, Amy R.; Noordam, Raymond; Sung, Yun Ju; Schwander, Karen; Winkler, Thomas W.; Jakupovic, Hermina; Chasman, Daniel I.; Manning, Alisa; Ntalla, Ioanna; Aschard, Hugues; Brown, Michael R.; de las Fuentes, Lisa; Franceschini, Nora; Guo, Xiuqing; Vojinovic, Dina; Aslibekyan, Stella; Feitosa, Mary F.; Kho, Minjung; Musani, Solomon K. ... Loos, Ruth J. F. (2019). Multi-ancestry study of blood lipid levels identifies four loci interacting with physical activity. Nature Communications, 10, ARTN 376. DOI: 10.1038/s41467-018-08008-w.
1.1.
2019
Harold, Denise; Connolly, Siobhan; Riley, Brien P.; Kendler, Kenneth S.; McCarthy, Shane E.; McCombie, William R.; Richards, Alex; Owen, Michael J.; O'Donovan, Michael C.; Walters, James; Donnelly, Peter; Bates, Lesley; Barroso, Ines; Blackwell, Jenefer M.; Bramon, Elvira; Brown, Matthew A.; Casas, Juan P.; Corvin, Aiden; Deloukas, Panos; Duncanson, Audrey ... Morris, Derek W. (2019). Population-based identity-by-descent mapping combined with exome sequencing to detect rare risk variants for schizophrenia. American Journal of Medical Genetics Part B Neuropsychiatric Genetics, 180 (3), 223−231. DOI: 10.1002/ajmg.b.32716.
1.1.
2019
Shrine, Nick; Guyatt, Anna L.; Erzurumluoglu, A. Mesut; Jackson, Victoria E.; Hobbs, Brian D.; Melbourne, Carl A.; Batini, Chiara; Fawcett, Katherine A.; Song, Kijoung; Sakornsakolpat, Phuwanat; Li, Xingnan; Boxall, Ruth; Reeve, Nicola F.; Obeidat, Ma'en; Zhao, Jing Hua; Wielscher, Matthias; Weiss, Stefan; Kentistou, Katherine A.; Cook, James P.; Sun, Benjamin B. ... Wain, Louise, V (2019). New genetic signals for lung function highlight pathways and chronic obstructive pulmonary disease associations across multiple ancestries. Nature Genetics, 51 (3), 481−497.10.1038/s41588-018-0321-7.
1.1.
2019
Doerr, Marcus; Hamburg, Naomi M.; Mueller, Christian; Smith, Nicholas L.; Gustafsson, Stefan; Lehtimaeki, Terho; Teumer, Alexander; Zeller, Tanja; Li, Xiaohui; Lind, Lars; Raitakari, Olli T.; Voelker, Uwe; Blankenberg, Stefan; McKnight, Barbara; Morris, Andrew P.; Kaehoenen, Mika; Lemaitre, Rozenn N.; Wild, Philipp S.; Nauck, Matthias; Voelzke, Henry ... Schnabel, Renate B. (2019). Common Genetic Variation in Relation to Brachial Vascular Dimensions and Flow-Mediated Vasodilation. Circulation Genomic and Precision Medicine, 12 (2), ARTN e002409.10.1161/CIRCGEN.118.002409.
1.1.
2019
Justice, Anne E; Karaderi, Tugce; Highland, Heather M; Young, Kristin L; Graff, Mariaelisa; Lu, Yingchang; Turcot, Valérie; Auer, Paul L; Fine, Rebecca S; Guo, Xiuqing; Schurmann, Claudia; Lempradl, Adelheid; Marouli, Eirini; Mahajan, Anubha; Winkler, Thomas W; Locke, Adam E; Medina-Gomez, Carolina; Esko, Tõnu; Vedantam, Sailaja; Giri, Ayush ... Lindgren, Cecilia M (2019). Protein-coding variants implicate novel genes related to lipid homeostasis contributing to body-fat distribution. Nature Genetics, 51 (3), 452−469.10.1038/s41588-018-0334-2.
1.1.
2019
Gialluisi, Alessandro; Andlauer, Till F. M.; Mirza-Schreiber, Nazanin; Moll, Kristina; Becker, Jessica; Hoffmann, Per; Ludwig, Kerstin U.; Czamara, Darina; St Pourcain, Beate; Brandler, William; Honbolygo, Ferenc; Toth, Denes; Csepe, Valeria; Huguet, Guillaume; Morris, Andrew P.; Hulslander, Jacqueline; Willcutt, Erik G.; DeFries, John C.; Olson, Richard K.; Smith, Shelley D. ... Schulte-Koerne, Gerd (2019). Genome-wide association scan identifies new variants associated with a cognitive predictor of dyslexia. Translational Psychiatry, 9, ARTN 77.10.1038/s41398-019-0402-0.
1.1.
2019
Karasik, David; Zillikens, M. Carola; Hsu, Yi-Hsiang; Aghdassi, Ali; Akesson, Kristina; Amin, Najaf; Barroso, Ines; Bennett, David A.; Bertram, Lars; Bochud, Murielle; Borecki, Ingrid B.; Broer, Linda; Buchman, Aron S.; Byberg, Liisa; Campbell, Harry; Campos-Obando, Natalia; Cauley, Jane A.; Cawthon, Peggy M.; Chambers, John C.; Chen, Zhao ... Ohlsson, Claes (2019). Disentangling the genetics of lean mass. American Journal of Clinical Nutrition, 109 (2), 276−287.10.1093/ajcn/nqy272.
1.1.
2019
Morris, Andrew P.; Le, Thu H.; Wu, Haojia; Akbarov, Artur; van der Most, Peter J.; Hemani, Gibran; Smith, George Davey; Mahajan, Anubha; Gaulton, Kyle J.; Nadkarni, Girish N.; Valladares-Salgado, Adan; Wacher-Rodarte, Niels; Mychaleckyj, Josyf C.; Dueker, Nicole D.; Guo, Xiuqing; Hai, Yang; Haessler, Jeffrey; Kamatani, Yoichiro; Stilp, Adrienne M.; Zhu, Gu ... Franceschini, Nora (2019). Trans-ethnic kidney function association study reveals putative causal genes and effects on kidney-specific disease aetiologies. Nature Communications, 10, ARTN 29.10.1038/s41467-018-07867-7.
1.1.
2019
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2018
Evangelou, Evangelos; Warren, Helen R; Mosen-Ansorena, David; Mifsud, Borbala; Pazoki, Raha; Gao, He; Ntritsos, Georgios; Dimou, Niki; Cabrera, Claudia P; Karaman, Ibrahim; Ng, Fu Liang; Evangelou, Marina; Witkowska, Katarzyna; Tzanis, Evan; Hellwege, Jacklyn N; Giri, Ayush; Velez Edwards, Digna R; Sun, Yan V; Cho, Kelly; Gaziano, J Michael ... Caulfield, Mark J (2018). Publisher Correction: Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits. Nature Genetics, 50 (12), 1755−1755. DOI: 10.1038/s41588-018-0297-3.
1.1.
2017
Sánchez-Salguero, R.; Hevia, A.; Camarero, J. J.; Treydte, K.; Frank, D.; Crivellaro, A.; Domínguez-Delmás, M.; Hellman, L.; Kaczka, R.; Kaye, M.; Akhmetzyanov, L.; Ashiq, W.M.; Bhuyan, U.; Bondarenko, O.; Camisón, Á.; Camps, S.; García, V.C.; Vaz, F. C.; Gavrila, I. G.; Gulbranson, E. ... Volařík, D. (2017). An intensive tree-ring experience: Connecting education and research during the 25th European Dendroecological Fieldweek (Asturias, Spain). Dendrochronologia, 42, 80−93.10.1016/j.dendro.2016.12.005.
1.1.
2017
Lind, Lars; Ng, Esther; Ingelsson, Erik; Lindgren, Cecilia; Salihovic, Samira; van Bavel, Bert; Mahajan, Anubha; Lampa, Erik; Morris, Andrew P.; Lind, P. Monica (2017). Genetic and methylation variation in the CYP2B6 gene is related to circulating p,p '-dde levels in a population-based sample. Environment International, 212−218.10.1016/j.envint.2016.11.010.
1.1.
2017
Parra, Esteban J.; Mazurek, Andrew; Gignoux, Christopher R.; Sockell, Alexandra; Agostino, Michael; Morris, Andrew P.; Petty, Lauren E.; Hanis, Craig L.; Cox, Nancy J.; Valladares-Salgado, Adan; Below, Jennifer E.; Cruz, Miguel (2017). Admixture mapping in two Mexican samples identifies significant associations of locus ancestry with triglyceride levels in the BUD13/ZNF259/APOA5 region and fine mapping points to rs964184 as the main driver of the association signal. PLoS ONE, 2, ARTN e0172880. DOI: 10.1371/journal.pone.0172880.
1.1.
2017
Asimit, Jennifer L.; Payne, Felicity; Morris, Andrew P.; Cordell, Heather J.; Barroso, Ines (2017). A two-stage inter-rater approach for enrichment testing of variants associated with multiple traits. European Journal of Human Genetics, 3, 341−349.10.1038/ejhg.2016.171.
1.1.
2017
Wain, Louise V.; Shrine, Nick; Artigas, Maria Soler; Erzurumluoglu, A. Mesut; Noyvert, Boris; Bossini-Castillo, Lara; Obeidat, Ma'en; Henrys, Amanda P.; Portelli, Michael A.; Hall, Robert J.; Billington, Charlotte K.; Rimington, Tracy L.; Fenech, Anthony G.; John, Catherine; Blake, Tineka; Jackson, Victoria E.; Allen, Richard J.; Prins, Bram P.; Campbell, Archie; Porteous, David J. ... Tobin, Martin D. (2017). Genome-wide association analyses for lung function and chronic obstructive pulmonary disease identify new loci and potential druggable targets. Nature Genetics, 3, 416−425.10.1038/ng.3787.
1.1.
2017
Uimari, Outi; Rahmioglu, Nilufer; Nyholt, Dale R.; Vincent, Katy; Missmer, Stacey A.; Becker, Christian; Morris, Andrew P.; Montgomery, Grant W.; Zondervan, Krina T. (2017). Genome-wide genetic analyses highlight mitogen-activated protein kinase (MAPK) signaling in the pathogenesis of endometriosis. Human Reproduction, 4, 780−793.10.1093/humrep/dex024.
1.1.
2017
van Rooij, Frank J. A.; Qayyum, Rehan; Smith, Albert V.; Zhou, Yi; Trompet, Stella; Tanaka, Toshiko; Keller, Margaux F.; Chang, Li-Ching; Schmidt, Helena; Yang, Min-Lee; Chen, Ming-Huei; Hayes, James; Johnson, Andrew D.; Yanek, Lisa R.; Mueller, Christian; Lange, Leslie; Floyd, James S.; Ghanbari, Mohsen; Zonderman, Alan B.; Jukema, J. Wouter ... Ganesh, Santhi K. (2017). Genome-wide Trans-ethnic Meta-analysis Identifies Seven Genetic Loci Influencing Erythrocyte Traits and a Role for RBPMS in Erythropoiesis. The American Journal of Human Genetics, 1, 51−63.10.1016/j.ajhg.2016.11.016.
1.1.
2017
Cook, James P.; Mahajan, Anubha; Morris, Andrew P. (2017). Guidance for the utility of linear models in meta-analysis of genetic association studies of binary phenotypes. European Journal of Human Genetics, 2, 240−245.10.1038/ejhg.2016.150.
1.1.
2017
Kaakinen, Marika; Magi, Reedik; Fischer, Krista; Heikkinen, Jani; Jarvelin, Marjo-Riitta; Morris, Andrew P.; Prokopenko, Inga (2017). MARV: a tool for genome-wide multi-phenotype analysis of rare variants. BMC Bioinformatics, ARTN 110. DOI: 10.1186/s12859-017-1530-2.
1.1.
2017
Mägi, Reedik; Suleimanov, Yury V.; Clarke, Geraldine M.; Kaakinen, Marika; Fischer, Krista; Prokopenko, Inga; Morris, Andrew P. (2017). SCOPA and META-SCOPA: software for the analysis and aggregation of genome-wide association studies of multiple correlated phenotypes. BMC Bioinformatics, ARTN 25.10.1186/s12859-016-1437-3.
1.1.
2017
Manning, Alisa; Highland, Heather M.; Gasser, Jessica; Sim, Xueling; Tukiainen, Taru; Fontanillas, Pierre; Grarup, Niels; Rivas, Manuel A.; Mahajan, Anubha; Locke, Adam E.; Cingolani, Pablo; Pers, Tune H.; Vinuela, Ana; Brown, Andrew A.; Wu, Ying; Flannick, Jason; Fuchsberger, Christian; Gamazon, Eric R.; Gaulton, Kyle J.; Im, Hae Kyung ... Lindgren, Cecilia M. (2017). A Low-Frequency Inactivating AKT2 Variant Enriched in the Finnish Population Is Associated With Fasting Insulin Levels and Type 2 Diabetes Risk. Diabetes, 66 (7), 2019−2032. DOI: 10.2337/db16-1329.
1.1.
2017
Marshall, Christian R.; Marshall, Christian R.; Howrigan, Daniel P.; Merico, Daniele; Thiruvahindrapuram, Bhooma; Wu, Wenting; Greer, Douglas S.; Antaki, Danny; Shetty, Aniket; Holmans, Peter A.; Pinto, Dalila; Gujral, Madhusudan; Brandler, William M.; Malhotra, Dheeraj; Wang, Zhouzhi; Fajarado, Karin V. Fuentes; Maile, Michelle S.; Ripke, Stephan; Agartz, Ingrid; Albus, Margot ... Sebat, Jonathan (2017). Contribution of copy number variants to schizophrenia from a genome-wide study of 41,321 subjects. Nature Genetics, 1, 27−35. DOI: 10.1038/ng.3725.
1.1.
2017
Warren, Helen R.; Evangelou, Evangelos; Cabrera, Claudia P.; Gao, He; Ren, Meixia; Mifsud, Borbala; Ntalla, Ioanna; Surendran, Praveen; Liu, Chunyu; Cook, James P.; Kraja, Aldi T.; Drenos, Fotios; Loh, Marie; Verweij, Niek; Marten, Jonathan; Karaman, Ibrahim; Lepe, Marcelo P. Segura; O'Reilly, Paul F.; Knight, Joanne; Snieder, Harold ... Ehret, Georg B. (2017). Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk. Nature Genetics, 3, 403−415. DOI: 10.1038/ng.3768.
1.1.
2017
Justice, Anne E.; Winkler, Thomas W.; Feitosa, Mary F.; Graff, Misa; Fisher, Virginia A.; Young, Kristin; Barata, Llilda; Deng, Xuan; Czajkowski, Jacek; Hadley, David; Ngwa, Julius S.; Ahluwalia, Tarunveer S.; Chu, Audrey Y.; Heard-Costa, Nancy L.; Lim, Elise; Perez, Jeremiah; Eicher, John D.; Kutalik, Zoltan; Xue, Luting; Mahajan, Anubha ... Cupples, L. Adrienne (2017). Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits. Nature Communications, 8 (14977), ARTN 14977. DOI: 10.1038/ncomms14977.
1.1.
2017
Mitt, Mario; Kals, Mart; Parn, Kalle; Gabriel, Stacey B; Lander, Eric S; Palotie, Aarno; Ripatti, Samuli; Morris, Andrew P; Metspalu, Andres; Esko, Tonu; Magi, Reedik; Palta, Priit; (2017). Improved imputation accuracy of rare and low-frequency variants using population-specific high-coverage WGS-based imputation reference panel. European Journal of Human Genetics, 25 (7), 869−879. DOI: 10.1038/ejhg.2017.51.
1.1.
2017
Wain, Louise V.; Vaez, Ahmad; Jansen, Rick; Joehanes, Roby; van der Most, Peter J.; Erzurumluoglu, A. Mesut; O'Reilly, Paul F.; Cabrera, Claudia P.; Warren, Helen R.; Rose, Lynda M.; Verwoert, Germaine C.; Hottenga, Jouke-Jan; Strawbridge, Rona J.; Esko, Tõnu; Arking, Dan E.; Hwang, Shih-Jen; Guo, Xiuqing; Kutalik, Zoltan; Trompet, Stella; Shrine, Nick ... Xiao, Limin (2017). Novel Blood Pressure Locus and Gene Discovery Using Genome-Wide Association Study and Expression Data Sets From Blood and the Kidney. Hypertension, 70 (3), e4−e19. DOI: 10.1161/HYPERTENSIONAHA.117.09438.
1.1.
2017
Shungin, Dmitry; Deng, Wei Q.; Varga, Tibor V.; Luan, Jian'an; Mihailov, Evelin; Metspalu, Andres; Morris, Andrew P.; Forouhi, Nita G.; Lindgren, Cecilia; Magnusson, Patrik K. E.; Pedersen, Nancy L.; Hallmans, Goran; Chu, Audrey Y.; Justice, Anne E.; Graff, Mariaelisa; Winkler, Thomas W.; Rose, Lynda M.; Langenberg, Claudia; Cupples, L. Adrienne; Ridker, Paul M. ... Franks, Paul W. (2017). Ranking and characterization of established BMI and lipid associated loci as candidates for gene-environment interactions. PLoS Genetics, 13 (6), e1006812. DOI: 10.1371/journal.pgen.1006812.
1.1.
2017
Marouli, Eirini; Graff, Mariaelisa; Medina-Gomez, Carolina; Lo, Ken Sin; Wood, Andrew R.; Kjaer, Troels R.; Fine, Rebecca S.; Lu, Yingchang; Schurmann, Claudia; Highland, Heather M.; Rueger, Sina; Thorleifsson, Gudmar; Justice, Anne E.; Lamparter, David; Stirrups, Kathleen E.; Turcot, Valerie; Young, Kristin L.; Winkler, Thomas W.; Esko, Tonu; Karaderi, Tugce ... Lettre, Guillaume (2017). Rare and low-frequency coding variants alter human adult height. Nature, 7640, 186−190. DOI: 10.1038/nature21039.
1.1.
2017
Webb, Thomas R.; Erdmann, Jeanette; Stirrups, Kathleen E.; Stitziel, Nathan O.; Masca, Nicholas G. D.; Jansen, Henning; Kanoni, Stavroula; Nelson, Christopher P.; Ferrario, Paola G.; Koenig, Inke R.; Eicher, John D.; Johnson, Andrew D.; Hamby, Stephen E.; Betsholtz, Christer; Ruusalepp, Arno; Franzen, Oscar; Schadt, Eric E.; Bjoerkegren, Johan L. M.; Weeke, Peter E.; Auer, Paul L. ... Kathiresan, Sekar (2017). Systematic Evaluation of Pleiotropy Identifies 6 Further Loci Associated With Coronary Artery Disease. Journal of the American College of Cardiology, 7, 823−836. DOI: 10.1016/j.jacc.2016.11.056.
1.1.
2017
Rahmioglu, Nilufer; Drong, Alexander W; Lockstone, Helen; Tapmeier, Thomas; Hellner, Karin; Saare, Merli; Laisk-Podar, Triin; Dew, Christine; Tough, Emily; Nicholson, George; Peters, Maire; Morris, Andrew P; Lindgren, Cecilia M; Becker, Christian M; Zondervan, Krina T (2017). Variability of genome-wide DNA methylation and mRNA expression profiles in reproductive and endocrine disease related tissues. Epigenetics, 12 (10), 897−908. DOI: 10.1080/15592294.2017.1367475.
1.1.
2017
Below, Jennifer E.; Parra, Esteban J.; Gamazon, Eric R.; Torres, Jason; Krithika, S.; Candille, Sophie; Lu, Yingchang; Manichakul, Ani; Peralta-Romero, Jesus; Duan, Qing; Li, Yun; Morris, Andrew P.; Gottesman, Omri; Bottinger, Erwin; Wang, Xin-Qun; Taylor, Kent D.; Chen, Y. -D. Ida; Rotter, Jerome I.; Rich, Stephen S.; Loos, Ruth J. F. ... Valladares-Salgado, Adan (2017). Meta-analysis of lipid-traits in Hispanics identifies novel loci, population-specific effects, and tissue-specific enrichment of eQTLs. Scientific Reports, 6 (19429), 1−13.10.1038/srep19429.
1.1.
2017
Kaakinen, Marika; Magi, Reedik; Fischer, Krista; Heikkinen, Jani; Jarvelin, Marjo-Riitta; Morris, Andrew P.; Prokopenko, Inga (2017). A rare-variant test for high-dimensional data. European Journal of Human Genetics, 25 (8), 988−994.10.1038/ejhg.2017.90.
1.1.
2017
Flannick, Jason; Fuchsberger, Christian; Mahajan, Anubha; Teslovich, Tanya M.; Agarwala, Vineeta; Gaulton, Kyle J.; Caulkins, Lizz; Koesterer, Ryan; Ma, Clement; Moutsianas, Loukas; McCarthy, Davis J.; Rivas, Manuel A.; Perry, John R. B.; Sim, Xueling; Blackwell, Thomas W.; Robertson, Neil R.; Rayner, N. William; Cingolani, Pablo; Locke, Adam E.; Tajes, Juan Fernandez ... McCarthy, Mark I. (2017). Data Descriptor: Sequence data and association statistics from 12,940 type 2 diabetes cases and controls. Scientific Data, 4, ARTN 170179. DOI: 10.1038/sdata.2017.179.
1.1.
2017
Liu, Dajiang J.; Peloso, Gina M.; Yu, Haojie; Butterworth, Adam S.; Wang, Xiao; Mahajan, Anubha; Saleheen, Danish; Emdin, Connor; Alam, Dewan; Alves, Alexessander Couto; Amouyel, Philippe; Di Angelantonio, Emanuele; Arveiler, Dominique; Assimes, Themistocles L.; Auer, Paul L.; Baber, Usman; Ballantyne, Christie M.; Bang, Lia E.; Benn, Marianne; Bis, Joshua C. ... Kathiresan, Sekar (2017). Exome-wide association study of plasma lipids in > 300,000 individuals. Nature Genetics, 49 (12), 1758−1772. DOI: 10.1038/ng.3977.
1.1.
2017
Strawbridge, Rona J; Silveira, Angela; Hoed, Marcel den; Gustafsson, Stefan; Luan, Jian'an; Rybin, Denis; Dupuis, Josée; Li-Gao, Ruifang; Kavousi, Maryam; Dehghan, Abbas; Haljas, Kadri; Lahti, Jari; Gådin, Jesper R; Bäcklund, Alexandra; de Faire, Ulf; Gertow, Karl; Giral, Phillipe; Goel, Anuj; Humphries, Steve E; Kurl, Sudhir ... , (2017). Identification of a novel proinsulin-associated SNP and demonstration that proinsulin is unlikely to be a causal factor in subclinical vascular remodelling using Mendelian randomisation. Atherosclerosis, 266, 196−204.10.1016/j.atherosclerosis.2017.09.031.
1.1.
2017
Kraja, Aldi T.; Cook, James P.; Warren, Helen R.; Surendran, Praveen; Liu, Chunyu; Evangelou, Evangelos; Manning, Alisa K.; Grarup, Niels; Drenos, Fotios; Sim, Xueling; Smith, Albert Vernon; Amin, Najaf; Blakemore, Alexandra I. F.; Bork-Jensen, Jette; Brandslund, Ivan; Farmaki, Aliki-Eleni; Fava, Cristiano; Ferreira, Teresa; Herzig, Karl-Heinz; Giri, Ayush ... Howson, Joanna M. M. (2017). New Blood Pressure-Associated Loci Identified in Meta-Analyses of 475000 Individuals. Circulation Cardiovascular Genetics, 10 (5), UNSP e001778.10.1161/CIRCGENETICS.117.001778.
1.1.
2017
Mägi, R; Horikoshi, M; Sofer, T; Mahajan, A; Kitajima, H; Franceschini, N; McCarthy, MI; COGENT-Kidney, Consortium; T2D-GENES, Consortium; Morris, AP (2017). Trans-ethnic meta-regression of genome-wide association studies accounting for ancestry increases power for discovery and improves fine-mapping resolution. Human Molecular Genetics, 26 (18), 3639−3650.10.1093/hmg/ddx280.
1.1.
2017
Flannick J, Fuchsberger C, Mahajan A, Teslovich TM, Agarwala V, Gaulton KJ, Caulkins L, Koesterer R, Ma C, Moutsianas L, McCarthy DJ, Rivas MA, Perry JRB, Sim X, Blackwell TW, Robertson NR, Rayner NW, Cingolani P, Locke AE, Tajes JF, Highland HM, Dupuis J, Chines PS, Lindgren CM, Hartl C, Jackson AU, Chen H, Huyghe JR, van de Bunt M, Pearson RD, Kumar A, Müller-Nurasyid M, Grarup N, Stringham HM, Gamazon ER, Lee J, Chen Y, Scott RA, Below JE, Chen P, Huang J, Go MJ, Stitzel ML, Pasko D, Parker SCJ, Varga TV, Green T, Beer NL, Day-Williams AG, Ferreira T, Fingerlin T, Horikoshi M, Hu C, Huh I, Ikram MK, Kim BJ, Kim Y, Kim YJ, Kwon MS, Lee J, Lee S, Lin KH, Maxwell TJ, Nagai Y, Wang X, Welch RP, Yoon J, Zhang W, Barzilai N, Voight BF, Han BG, Jenkinson CP, Kuulasmaa T, Kuusisto J, Manning A, Ng MCY, Palmer ND, Balkau B, Stančáková A, Abboud HE, Boeing H, Giedraitis V, Prabhakaran D, Gottesman O, Scott J, Carey J, Kwan P, Grant G, Smith JD, Neale BM, Purcell S, Butterworth AS, Howson JMM, Lee HM, Lu Y, Kwak SH, Zhao W, Danesh J, Lam VKL, Park KS, Saleheen D, So WY, Tam CHT, Afzal U, Aguilar D, Arya R, Aung T, Chan E, Navarro C, Cheng CY, Palli D, Correa A, Curran JE, Rybin D, Farook VS, Fowler SP, Freedman BI, Griswold M, Hale DE, Hicks PJ, Khor CC, Kumar S, Lehne B, Thuillier D, Lim WY, Liu J, Loh M, Musani SK, Puppala S, Scott WR, Yengo L, Tan ST, Taylor HA, Thameem F, Wilson G, Wong TY, Njølstad PR, Levy JC, Mangino M, Bonnycastle LL, Schwarzmayr T, Fadista J, Surdulescu GL, Herder C, Groves CJ, Wieland T, Bork-Jensen J, Brandslund I, Christensen C, Koistinen HA, Doney ASF, Kinnunen L, Esko T, Farmer AJ, Hakaste L, Hodgkiss D, Kravic J, Lyssenko V, Hollensted M, Jørgensen ME, Jørgensen T, Ladenvall C, Justesen JM, Käräjämäki A, Kriebel J, Rathmann W, Lannfelt L, Lauritzen T, Narisu N, Linneberg A, Melander O, Milani L, Neville M, Orho-Melander M, Qi L, Qi Q, Roden M, Rolandsson O, Swift A, Rosengren AH, Stirrups K, Wood AR, Mihailov E, Blancher C, Carneiro MO, Maguire J, Poplin R, Shakir K, Fennell T, DePristo M, de Angelis MH, Deloukas P, Gjesing AP, Jun G, Nilsson P, Murphy J, Onofrio R, Thorand B, Hansen T, Meisinger C, Hu FB, Isomaa B, Karpe F, Liang L, Peters A, Huth C, O'Rahilly SP, Palmer CNA, Pedersen O, Rauramaa R, Tuomilehto J, Salomaa V, Watanabe RM, Syvänen AC, Bergman RN, Bharadwaj D, Bottinger EP, Cho YS, Chandak GR, Chan JC, Chia KS, Daly MJ, Ebrahim SB, Langenberg C, Elliott P, Jablonski KA, Lehman DM, Jia W, Ma RCW, Pollin TI, Sandhu M, Tandon N, Froguel P, Barroso I, Teo YY, Zeggini E, Loos RJF, Small KS, Ried JS, DeFronzo RA, Grallert H, Glaser B, Metspalu A, Wareham NJ, Walker M, Banks E, Gieger C, Ingelsson E, Im HK, Illig T, Franks PW, Buck G, Trakalo J, Buck D, Prokopenko I, Mägi R, Lind L, Farjoun Y, Owen KR, Gloyn AL, Strauch K, Tuomi T, Kooner JS, Lee JY, Park T, Donnelly P, Morris AD, Hattersley AT, Bowden DW, Collins FS, Atzmon G, Chambers JC, Spector TD, Laakso M, Strom TM, Bell GI, Blangero J, Duggirala R, Tai ES, McVean G, Hanis CL, Wilson JG, Seielstad M, Frayling TM, Meigs JB, Cox NJ, Sladek R, Lander ES, Gabriel S, Mohlke KL, Meitinger T, Groop L, Abecasis G, Scott LJ, Morris AP, Kang HM, Altshuler D, Burtt NP, Florez JC, Boehnke M, McCarthy MI. (2017). Sequence data and association statistics from 12,940 type 2 diabetes cases and controls. Scientific Data, 4, 170179. DOI: 10.1038/sdata.2017.179.
1.1.
2017
Sapkota, Yadav; De Vivo, Immaculata; Steinthorsdottir, Valgerdur; Fassbender, Amelie; Bowdler, Lisa; Buring, Julie E.; Edwards, Todd L.; Jones, Sarah; Dorien, O.; Peterse, Danielle; Rexrode, Kathryn M.; Ridker, Paul M.; Schork, Andrew J.; Thorleifsson, Gudmar; Wallace, Leanne M.; Kraft, Peter; Morris, Andrew P.; Nyholt, Dale R.; Edwards, Digna R. Velez; Nyegaard, Mette ... Montgomery, Grant W. (2017). Analysis of potential protein-modifying variants in 9000 endometriosis patients and 150000 controls of European ancestry. Scientific Reports, 7, ARTN 11380.10.1038/s41598-017-10440-9.
1.1.
2017
Wheeler, Eleanor; Leong, Aaron; Liu, Ching-Ti; Hivert, Marie-France; Strawbridge, Rona J.; Podmore, Clara; Li, Man; Yao, Jie; Sim, Xueling; Hong, Jaeyoung; Chu, Audrey Y.; Zhang, Weihua; Wang, Xu; Chen, Peng; Maruthur, Nisa M.; Porneala, Bianca C.; Sharp, Stephen J.; Jia, Yucheng; Kabagambe, Edmond K.; Chang, Li-Ching ... Meigs, James B. (2017). Impact of common genetic determinants of Hemoglobin A1c on type 2 diabetes risk and diagnosis in ancestrally diverse populations: A transethnic genome-wide meta-analysis. PLoS Medicine, 14 (9), ARTN e1002383.10.1371/journal.pmed.1002383.
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2017
Nolte, Ilja M.; Munoz, M. Loretto; Tragante, Vinicius; Amare, Azmeraw T.; Jansen, Rick; Vaez, Ahmad; von der Heyde, Benedikt; Avery, Christy L.; Bis, Joshua C.; Dierckx, Bram; van Dongen, Jenny; Gogarten, Stephanie M.; Goyette, Philippe; Hernesniemi, Jussi; Huikari, Ville; Hwang, Shih-Jen; Jaju, Deepali; Kerr, Kathleen F.; Kluttig, Alexander; Krijthe, Bouwe P. ... de Geus, Eco J. C. (2017). Genetic loci associated with heart rate variability and their effects on cardiac disease risk. Nature Communications, 8, ARTN 15805.10.1038/ncomms15805.
1.1.
2017
Windholz, Jan; Kovacs, Peter; Schlicke, Marina; Franke, Christin; Mahajan, Anubha; Morris, Andrew P.; Lemke, Johannes R.; Klammt, Juergen; Kiess, Wieland; Schoeneberg, Torsten; Paeffle, Roland; Koerner, Antje (2017). Copy number variations in "classical" obesity candidate genes are not frequently associated with severe early-onset obesity in children. Journal of Pediatric Endocrinology and Metabolism, 30 (5), 507−515.10.1515/jpem-2016-0435.
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2017
Scott, Robert A.; Scott, Laura J.; Maegi, Reedik; Marullo, Letizia; Gaulton, Kyle J.; Kaakinen, Marika; Pervjakova, Natalia; Pers, Tune H.; Johnson, Andrew D.; Eicher, John D.; Jackson, Anne U.; Ferreira, Teresa; Lee, Yeji; Ma, Clement; Steinthorsdottir, Valgerdur; Thorleifsson, Gudmar; Qi, Lu; Van Zuydam, Natalie R.; Mahajan, Anubha; Chen, Han ... Prokopenko, Inga (2017). An Expanded Genome-Wide Association Study of Type 2 Diabetes in Europeans. Diabetes, 66 (11), 2888−2902. DOI: 10.2337/db16-1253.
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2017
Tachmazidou, Ioanna; Suveges, Daniel; Min, Josine L.; Ritchie, Graham R. S.; Steinberg, Julia; Walter, Klaudia; Iotchkova, Valentina; Schwartzentruber, Jeremy; Huang, Jie; Memari, Yasin; McCarthy, Shane; Crawford, Andrew A.; Bombieri, Cristina; Cocca, Massimiliano; Farmaki, Aliki-Eleni; Gaunt, Tom R.; Jousilahti, Pekka; Kooijman, Marjolein N.; Lehne, Benjamin; Malerba, Giovanni ... Zeggini, Eleftheria (2017). Whole-Genome Sequencing Coupled to Imputation Discovers Genetic Signals for Anthropometric Traits. The American Journal of Human Genetics, 100 (6), 865−884.10.1016/j.ajhg.2017.04.014.
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2017
Sapkota, Yadav; Steinthorsdottir, Valgerdur; Morris, Andrew P.; Fassbender, Amelie; Rahmioglu, Nilufer; De Vivo, Immaculata; Buring, Julie E.; Zhang, Futao; Edwards, Todd L.; Jones, Sarah; Dorien, O.; Peterse, Danielle; Rexrode, Kathryn M.; Ridker, Paul M.; Schork, Andrew J.; MacGregor, Stuart; Martin, Nicholas G.; Becker, Christian M.; Adachi, Sosuke; Yoshihara, Kosuke ... Nyholt, Dale R. (2017). Meta-analysis identifies five novel loci associated with endometriosis highlighting key genes involved in hormone metabolism. Nature Communications, 8, ARTN 15539.10.1038/ncomms15539.
1.1.
2017
Syed, Hamzah; Jorgensen, Andrea L.; Morris, Andrew P. (2017). SurvivalGWAS_SV: software for the analysis of genome-wide association studies of imputed genotypes with "time-to-event" outcomes. BMC Bioinformatics, 18, ARTN 265.10.1186/s12859-017-1683-z.
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2017
Christophersen, Ingrid E.; Rienstra, Michiel; Roselli, Carolina; Yin, Xiaoyan; Geelhoed, Bastiaan; Barnard, John; Lin, Honghuang; Arking, Dan E.; Smith, Albert V.; Albert, Christine M.; Chaffin, Mark; Tucker, Nathan R.; Li, Molong; Klarin, Derek; Bihlmeyer, Nathan A.; Low, Siew-Kee; Weeke, Peter E.; Mueller-Nurasyid, Martina; Smith, J. Gustav; Brody, Jennifer A. ... Ellinor, Patrick T. (2017). Large-scale analyses of common and rare variants identify 12 new loci associated with atrial fibrillation. Nature Genetics, 49 (6), 946−956.10.1038/ng.3843.
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2017
Wild, Philipp S.; Felix, Janine F.; Schillert, Arne; Teumer, Alexander; Chen, Ming-Huei; Leening, Maarten J. G.; Voelker, Uwe; Grossmann, Vera; Brody, Jennifer A.; Irvin, Marguerite R.; Shah, Sanjiv J.; Pramana, Setia; Lieb, Wolfgang; Schmidt, Reinhold; Stanton, Alice V.; Malzahn, Doerthe; Smith, Albert Vernon; Sundstrom, Johan; Minelli, Cosetta; Ruggiero, Daniela ... Doerr, Marcus (2017). Large-scale genome-wide analysis identifies genetic variants associated with cardiac structure and function. Journal of Clinical Investigation, 127 (5), 1798−1812.10.1172/JCI84840.
1.1.
2017
Turner, Richard M.; Yin, Peng; Hanson, Anita; FitzGerald, Richard; Morris, Andrew P.; Stables, Rod H.; Jorgensen, Andrea L.; Pirmohamed, Munir (2017). Investigating the prevalence, predictors, and prognosis of suboptimal statin use early after a non-ST elevation acute coronary syndrome. Journal of Clinical Lipidology, 11 (1), 204−214.10.1016/j.jacl.2016.12.007.
1.1.
2017
Folkersen, Lasse; Fauman, Eric; Sabater-Lleal, Maria; Strawbridge, Rona J.; Franberg, Mattias; Sennblad, Bengt; Baldassarre, Damiano; Veglia, Fabrizio; Humphries, Steve E.; Rauramaa, Rainer; de Faire, Ulf; Smit, Andries J.; Giral, Philippe; Kurl, Sudhir; Mannarino, Elmo; Enroth, Stefan; Johansson, Asa; Enroth, Sofia Bosdotter; Gustafsson, Stefan; Lind, Lars ... Malarstig, Anders (2017). Mapping of 79 loci for 83 plasma protein biomarkers in cardiovascular disease. PLoS Genetics, 13 (4), ARTN e1006706.10.1371/journal.pgen.1006706.
1.1.
2017
Hu, Yao; Tanaka, Toshiko; Zhu, Jingwen; Guan, Weihua; Wu, Jason H. Y.; Psaty, Bruce M.; McKnight, Barbara; King, Irena B.; Sun, Qi; Richard, Melissa; Manichaikul, Ani; Frazier-Wood, Alexis C.; Kabagambe, Edmond K.; Hopkins, Paul N.; Ordovas, Jose M.; Ferrucci, Luigi; Bandinelli, Stefania; Arnett, Donna K.; Chen, Yii-Der I.; Liang, Shuang ... Lin, Xu (2017). Discovery and fine-mapping of loci associated with MUFAs through trans-ethnic meta-analysis in Chinese and European populations. The Journal of Lipid Research, 58 (5), 974−981.10.1194/jlr.P071860.
1.1.
2017
Carr, Daniel F.; Bourgeois, Stephane; Chaponda, Mas; Takeshita, Louise Y.; Morris, Andrew P.; Castro, Elena M. Cornejo; Alfirevic, Ana; Jones, Andrew R.; Rigden, Daniel J.; Haldenby, Sam; Khoo, Saye; Lalloo, David G.; Heyderman, Robert S.; Dandara, Collet; Kampira, Elizabeth; van Oosterhout, Joep J.; Ssali, Francis; Munderi, Paula; Novelli, Giuseppe; Borgiani, Paola ... Pirmohamed, Munir (2017). Genome-wide association study of nevirapine hypersensitivity in a sub-Saharan African HIV-infected population. Journal of Antimicrobial Chemotherapy, 72 (4), 1152−1162. DOI: 10.1093/jac/dkw545.
1.1.
2017
Zillikens, M. Carola; Demissie, Serkalem; Hsu, Yi-Hsiang; Yerges-Armstrong, Laura M.; Chou, Wen-Chi; Stolk, Lisette; Livshits, Gregory; Broer, Linda; Johnson, Toby; Koller, Daniel L.; Kutalik, Zoltyn; Luan, Jian'an; Malkin, Ida; Ried, Janina S.; Smith, Albert V.; Thorleifsson, Gudmar; Vandenput, Liesbeth; Zhao, Jing Hua; Zhang, Weihua; Aghdassi, Ali ... Kiel, Douglas P. (2017). Large meta-analysis of genome-wide association studies identifies five loci for lean body mass. Nature Communications, 8, ARTN 80.10.1038/s41467-017-00031-7.
5.1.
2017
Rahmioglu, Nilufer; Lockstone, Helen; Ferreira, Teresa; Magi, Reedik; Van De Bunt, Martijn; Lindgren, Cecilia; Morris, Andrew; Becker, Christian; Zondervan, Krina (2017). Large-Scale Integrated Genome-Wide RNA Sequencing, miRNA Array, and Genomic Analyses to Unravel the Functionality of Genome-Wide Association Results in Endometriosis. Reproductive Sciences, 24, 205A−206A.
5.1.
2017
Kaakinen, Marika; Magi, Reedik; Lagou, Vasiliki; Claringbould, Annique; Gaulton, Kyle; Fischer, Krista; Morris, Andrew; Prokopenko, Inga (2017). Multi-Phenotype Genome-Wide Meta-Analysis of Lipid Levels and BMI in 64,736 Europeans Suggests Shared Genetic Architecture. Genetic Epidemiology, 41 (7), 652−653.
1.1.
2016
Fuchsberger, Christian; Flannick, Jason; Teslovich, Tanya M; Mahajan, Anubha; Agarwala, Vineeta; Gaulton, Kyle J; Ma, Clement; Fontanillas, Pierre; Moutsianas, Loukas; McCarthy, Davis J; Rivas, Manuel A; Perry, John R B; Sim, Xueling; Blackwell, Thomas W; Robertson, Neil R; Rayner, N William; Cingolani, Pablo; Locke, Adam E; Tajes, Juan Fernandez; Highland, Heather M ... McCarthy, Mark I (2016). The genetic architecture of type 2 diabetes. Nature, 536 (7614), 41−47. DOI: 10.1038/nature18642.
1.1.
2016
Lessard, Samuel; Manning, Alisa K; Low-Kam, Cécile; Auer, Paul L; Giri, Ayush; Graff, Mariaelisa; Schurmann, Claudia; Yaghootkar, Hanieh; Luan, Jian'an; Esko, Tonu; Karaderi, Tugce; Bottinger, Erwin P; Lu, Yingchang; Carlson, Chris; Caulfield, Mark; Dubé, Marie-Pierre; Jackson, Rebecca D; Kooperberg, Charles; McKnight, Barbara; Mongrain, Ian ... Lettre, Guillaume (2016). Testing the role of predicted gene knockouts in human anthropometric trait variation. Human Molecular Genetics, 25 (10), 1−11. DOI: 10.1093/hmg/ddw055.
1.1.
2016
Pattaro, Cristian; Teumer, Alexander; Gorski, Mathias; Chu, Audrey Y; Li, Man; Mijatovic, Vladan; Garnaas, Maija; Tin, Adrienne; Sorice, Rossella; Li, Yong; Taliun, Daniel; Olden, Matthias; Foster, Meredith; Yang, Qiong; Chen, Ming-Huei; Pers, Tune H; Johnson, Andrew D; Ko, Yi-An; Fuchsberger, Christian; Tayo, Bamidele ... Fox, Caroline S (2016). Genetic associations at 53 loci highlight cell types and biological pathways relevant for kidney function. Nature Communications, 7 (10023), 10023−10023. DOI: 10.1038/ncomms10023.
1.1.
2016
Pervjakova, Natalia; Kasela, Silva; Morris, Andrew P; Kals, Mart; Metspalu, Andres; Lindgren, Cecilia M; Salumets, Andres; Mägi, Reedik (2016). Imprinted genes and imprinting control regions show predominant intermediate methylation in adult somatic tissues. Epigenomics, 8 (6), 789−799. DOI: 10.2217/epi.16.8.
1.1.
2016
Lu, Yingchang; Day, Felix R; Gustafsson, Stefan; Buchkovich, Martin L; Na, Jianbo; Bataille, Veronique; Cousminer, Diana L; Dastani, Zari; Drong, Alexander W; Esko, Tõnu; Evans, David M; Falchi, Mario; Feitosa, Mary F; Ferreira, Teresa; Hedman, Åsa K; Haring, Robin; Hysi, Pirro G; Iles, Mark M; Justice, Anne E; Kanoni, Stavroula ... Loos, Ruth J F (2016). New loci for body fat percentage reveal link between adiposity and cardiometabolic disease risk. Nature Communications, 7, 10495−10495.10.1038/ncomms10495.
1.1.
2016
Ehret, Georg B; Ferreira, Teresa; Chasman, Daniel I; Jackson, Anne U; Schmidt, Ellen M; Johnson, Toby; Thorleifsson, Gudmar; Luan, Jian'an; Donnelly, Louise A; Kanoni, Stavroula; Petersen, Ann-Kristin; Pihur, Vasyl; Strawbridge, Rona J; Shungin, Dmitry; Hughes, Maria F; Meirelles, Osorio; Kaakinen, Marika; Bouatia-Naji, Nabila; Kristiansson, Kati; Shah, Sonia ... Munroe, Patricia B. (2016). The genetics of blood pressure regulation and its target organs from association studies in 342,415 individuals. Nature Genetics, 48 (10), 1171−1184. DOI: 10.1038/ng.3667.
1.1.
2016
Läll, Kristi; Mägi, Reedik; Morris, Andrew; Metspalu, Andres; Fischer, Krista (2016). Personalized risk prediction for type 2 diabetes: the potential of genetic risk scores. Genetics in Medicine, 1−10. DOI: 10.1038/gim.2016.103.
1.1.
2016
Scott, Robert A.; Freitag, Daniel F.; Li, Li; Chu, Audrey Y.; Surendran, Praveen; Young, Robin; Grarup, Niels; Stancakova, Alena; Chen, Yuning; Varga, Tibor V.; Yaghootkar, Hanieh; Luan, Jian'an; Zhao, Jing Hua; Willems, Sara M.; Wessel, Jennifer; Wang, Shuai; Maruthur, Nisa; Michailidou, Kyriaki; Pirie, Ailith; van der Lee, Sven J. ... Waterworth, Dawn M. (2016). A genomic approach to therapeutic target validation identifies a glucose-lowering GLP1R variant protective for coronary heart disease. Science Translational Medicine, 341, ARTN 341ra76.10.1126/scitranslmed.aad3744.
1.1.
2016
Ried JS, Jeff M J, Chu AY, Bragg-Gresham JL, van Dongen J, Huffman JE, Ahluwalia TS, Cadby G, Eklund N, Eriksson J, Esko T, Feitosa MF, Goel A, Gorski M, Hayward C, Heard-Costa NL, Jackson AU, Jokinen E, Kanoni S, Kristiansson K, Kutalik Z, Lahti J, Luan J, Mägi R, Mahajan A, Mangino M, Medina-Gomez C, Monda KL, Nolte IM, Pérusse L, Prokopenko I, Qi L, Rose LM, Salvi E, Smith MT, Snieder H, Stančáková A, Ju Sung Y, Tachmazidou I, Teumer A, Thorleifsson G, van der Harst P, Walker RW, Wang SR, Wild SH, Willems SM, Wong A, Zhang W, Albrecht E, Couto Alves A, Bakker SJ, Barlassina C, Bartz TM, Beilby J, Bellis C, Bergman RN, Bergmann S, Blangero J, Blüher M, Boerwinkle E, Bonnycastle LL, Bornstein SR, Bruinenberg M, Campbell H, Chen YI, Chiang CW, Chines PS, Collins FS, Cucca F, Cupples LA, D'Avila F, de Geus EJ, Dedoussis G, Dimitriou M, Döring A, Eriksson JG, Farmaki AE, Farrall M, Ferreira T, Fischer K, Forouhi NG, Friedrich N, Gjesing AP, Glorioso N, Graff M, Grallert H, Grarup N, Gräßler J, Grewal J, Hamsten A, Harder MN, Hartman CA, Hassinen M, Hastie N, Hattersley AT, Havulinna AS, Heliövaara M, Hillege H, Hofman A, Holmen O, Homuth G, Hottenga JJ, Hui J, Husemoen LL, Hysi PG, Isaacs A, Ittermann T, Jalilzadeh S, James AL, Jørgensen T, Jousilahti P, Jula A, Marie Justesen J, Justice AE, Kähönen M, Karaleftheri M, Tee Khaw K, Keinanen-Kiukaanniemi SM, Kinnunen L, Knekt PB, Koistinen HA, Kolcic I, Kooner IK, Koskinen S, Kovacs P, Kyriakou T, Laitinen T, Langenberg C, Lewin AM, Lichtner P, Lindgren CM, Lindström J, Linneberg A, Lorbeer R, Lorentzon M, Luben R, Lyssenko V, Männistö S, Manunta P, Leach IM, McArdle WL, Mcknight B, Mohlke KL, Mihailov E, Milani L, Mills R, Montasser ME, Morris AP, Müller G, Musk AW, Narisu N, Ong KK, Oostra BA, Osmond C, Palotie A, Pankow JS, Paternoster L, Penninx BW, Pichler I, Pilia MG, Polašek O, Pramstaller PP, Raitakari OT, Rankinen T, Rao DC, Rayner NW, Ribel-Madsen R, Rice TK, Richards M, Ridker PM, Rivadeneira F, Ryan KA, Sanna S, Sarzynski MA, Scholtens S, Scott RA, Sebert S, Southam L, Sparsø TH, Steinthorsdottir V, Stirrups K, Stolk RP, Strauch K, Stringham HM, Swertz MA, Swift AJ, Tönjes A, Tsafantakis E, van der Most PJ, Van Vliet-Ostaptchouk JV, Vandenput L, Vartiainen E, Venturini C, Verweij N, Viikari JS, Vitart V, Vohl MC, Vonk JM, Waeber G, Widén E, Willemsen G, Wilsgaard T, Winkler TW, Wright AF, Yerges-Armstrong LM, Hua Zhao J, Carola Zillikens M, Boomsma DI, Bouchard C, Chambers JC, Chasman DI, Cusi D, Gansevoort RT, Gieger C, Hansen T, Hicks AA, Hu F, Hveem K, Jarvelin MR, Kajantie E, Kooner JS, Kuh D, Kuusisto J, Laakso M, Lakka TA, Lehtimäki T, Metspalu A, Njølstad I, Ohlsson C, Oldehinkel AJ, Palmer LJ, Pedersen O, Perola M, Peters A, Psaty BM, Puolijoki H, Rauramaa R, Rudan I, Salomaa V, Schwarz PE, Shudiner AR, Smit JH, Sørensen TI, Spector TD, Stefansson K, Stumvoll M, Tremblay A, Tuomilehto J, Uitterlinden AG, Uusitupa M, Völker U, Vollenweider P, Wareham NJ, Watkins H, Wilson JF, Zeggini E, Abecasis GR, Boehnke M, Borecki IB, Deloukas P, van Duijn CM, Fox C, Groop LC, Heid IM, Hunter DJ, Kaplan RC, McCarthy MI, North KE, O'Connell JR, Schlessinger D, Thorsteinsdottir U, Strachan DP, Frayling T, Hirschhorn JN, Müller-Nurasyid M, Loos RJ. (2016). A principal component meta-analysis on multiple anthropometric traits identifies novel loci for body shape. Nature Communications, e13357, 1−11. DOI: 10.1038/ncomms13357.
1.1.
2016
Syed, Hamzah; Jorgensen, Andrea L.; Morris, Andrew P. (2016). Evaluation of methodology for the analysis of 'time-to-event' data in pharmacogenomic genome-wide association studies. Pharmacogenomics, 8, 907−915.10.2217/pgs.16.19.
1.1.
2016
Horikoshi, Momoko; Beaumont, Robin N.; Day, Felix R.; Warrington, Nicole M.; Kooijman, Marjolein N.; Fernandez-Tajes, Juan; Feenstra, Bjarke; van Zuydam, Natalie R.; Gaulton, Kyle J.; Grarup, Niels; Bradfield, Jonathan P.; Strachan, David P.; Li-Gao, Ruifang; Ahluwalia, Tarunveer S.; Kreiner, Eskil; Rueedi, Rico; Lyytikainen, Leo-Pekka; Cousminer, Diana L.; Wu, Ying; Thiering, Elisabeth ... Freathy, Rachel M. (2016). Genome-wide associations for birth weight and correlations with adult disease. Nature, 7624, 248−268.10.1038/nature19806.
1.1.
2016
Walford, Geoffrey A.; Gustafsson, Stefan; Rybin, Denis; Stancakova, Alena; Chen, Han; Liu, Ching-Ti; Hong, Jaeyoung; Jensen, Richard A.; Rice, Ken; Morris, Andrew P.; Magi, Reedik; Toenjes, Anke; Prokopenko, Inga; Kleber, Marcus E.; Delgado, Graciela; Silbernagel, Guenther; Jackson, Anne U.; Appel, Emil V.; Grarup, Niels; Lewis, Joshua P. ... Florez, Jose C. (2016). Genome-Wide Association Study of the Modified Stumvoll Insulin Sensitivity Index Identifies BCL2 and FAM19A2 as Novel Insulin Sensitivity Loci. Diabetes, 10, 3200−3211.10.2337/db16-0199.
1.1.
2016
Ek, Weronica E.; Hedman, Asa K.; Enroth, Stefan; Morris, Andrew P.; Lindgren, Cecilia M.; Mahajan, Anubha; Gustafsson, Stefan; Gyllensten, Ulf; Lind, Lars; Johansson, Asa (2016). Genome-wide DNA methylation study identifies genes associated with the cardiovascular biomarker GDF-15. Human Molecular Genetics, 4, 817−827.10.1093/hmg/ddv511.
1.1.
2016
Chauhan, Ganesh; Arnold, Corey R.; Chu, Audrey Y.; Fornage, Myriam; Reyahi, Azadeh; Bis, Joshua C.; Havulinna, Ald S.; Sargurupremraj, Muralidharan; Smith, Albert Vernon; Adams, Hieab H. H.; Choi, Seung Hoan; Pulit, Sara L.; Trompet, Stella; Garcia, Melissa E.; Manichaikul, Ani; Teumer, Alexander; Gustafsson, Stefan; Bartz, Traci M.; Bellenguez, Celine; Vidal, Jean Sebastien ... Debette, Stephanie (2016). Identification of additional risk loci for stroke and small vessel disease: a meta-analysis of genome-wide association studies. The Lancet Neurology, 7, 695−707. DOI: 10.1016/S1474-4422(16)00102-2.
1.1.
2016
Prins, Bram. P.; Abbasi, Ali; Wong, Anson; Vaez, Ahmad; Nolte, Ilja; Franceschini, Nora; Stuart, Philip E.; Achury, Javier Guterriez; Mistry, Vanisha; Bradfield, Jonathan P.; Valdes, Ana M.; Bras, Jose; Shatunov, Aleksey; Lu, Chen; Han, Buhm; Raychaudhuri, Soumya; Bevan, Steve; Mayes, Maureen D.; Tsoi, Lam C.; Evangelou, Evangelos ... Alizadeh, Behrooz Z. (2016). Investigating the Causal Relationship of C-Reactive Protein with 32 Complex Somatic and Psychiatric Outcomes: A Large-Scale Cross-Consortium Mendelian Randomization Study. PLoS Medicine, 6, ARTN e1001976.10.1371/journal.pmed.1001976.
1.1.
2016
Cook, James P.; Morris, Andrew P. (2016). Multi-ethnic genome-wide association study identifies novel locus for type 2 diabetes susceptibility. European Journal of Human Genetics, 8, 1175−1180.10.1038/ejhg.2016.17.
1.1.
2016
Syed, Hamzah; Jorgensen, Andrea L.; Morris, Andrew P. (2016). SurvivalGWAS_Power: a user friendly tool for power calculations in pharmacogenetic studies with "time to event" outcomes. BMC Bioinformatics, ARTN 523.10.1186/s12859-016-1407-9.
1.1.
2016
Mahajan, Anubha; Rodan, Aylin R.; Le, Thu H.; Gaulton, Kyle J.; Haessler, Jeffrey; Stilp, Adrienne M.; Kamatani, Yoichiro; Zhu, Gu; Sofer, Tamar; Puri, Sanjana; Schellinger, Jeffrey N.; Chu, Pei-Lun; Cechova, Sylvia; van Zuydam, Natalie; Arnlov, Johan; Flessner, Michael F.; Giedraitis, Vilmantas; Heath, Andrew C.; Kubo, Michiaki; Larsson, Anders ... Franceschini, Nora (2016). Trans-ethnic Fine Mapping Highlights Kidney-Function Genes Linked to Salt Sensitivity. The American Journal of Human Genetics, 3, 636−646.10.1016/j.ajhg.2016.07.012.
1.1.
2016
Liu, Ching-Ti; Raghavan, Sridharan; Maruthur, Nisa; Kabagambe, Edmond Kato; Hong, Jaeyoung; Ng, Maggie C. Y.; Hivert, Marie-France; Lu, Yingchang; An, Ping; Bentley, Amy R.; Drolet, Anne M.; Gaulton, Kyle J.; Guo, Xiuqing; Armstrong, Loren L.; Irvin, Marguerite R.; Li, Man; Lipovich, Leonard; Rybin, Denis V.; Taylor, Kent D.; Agyemang, Charles ... Meigs, James B. (2016). Trans-ethnic Meta-analysis and Functional Annotation Illuminates the Genetic Architecture of Fasting Glucose and Insulin. The American Journal of Human Genetics, 1, 56−75.10.1016/j.ajhg.2016.05.006.
1.1.
2016
Horikoshi, Momoko; Pasquali, Lorenzo; Wiltshire, Steven; Huyghe, Jeroen R.; Mahajan, Anubha; Asimit, Jennifer L.; Ferreira, Teresa; Locke, Adam E.; Robertson, Neil R.; Wang, Xu; Sim, Xueling; Fujita, Hayato; Hara, Kazuo; Young, Robin; Zhang, Weihua; Choi, Sungkyoung; Chen, Han; Kaur, Ismeet; Takeuchi, Fumihiko; Fontanillas, Pierre ... Morris, Andrew P. (2016). Transancestral fine-mapping of four type 2 diabetes susceptibility loci highlights potential causal regulatory mechanisms. Human Molecular Genetics, 10, 2070−2081.10.1093/hmg/ddw048.
1.1.
2016
Asimit, Jennifer L.; Hatzikotoulas, Konstantinos; McCarthy, Mark; Morris, Andrew P.; Zeggini, Eleftheria (2016). Trans-ethnic study design approaches for fine-mapping. European Journal of Human Genetics, 9, 1330−1336.10.1038/ejhg.2016.1.
1.1.
2016
Loley C, Alver M, Assimes TL, Bjonnes A, Goel A, Gustafsson S, Hernesniemi J, Hopewell JC, Kanoni S, Kleber ME, Lau KW, Lu Y, Lyytikäinen LP, Nelson CP, Nikpay M, Qu L, Salfati E, Scholz M, Tukiainen T, Willenborg C, Won HH, Zeng L, Zhang W, Anand SS, Beutner F, Bottinger EP, Clarke R, Dedoussis G, Do R, Esko T, Eskola M, Farrall M, Gauguier D, Giedraitis V, Granger CB, Hall AS, Hamsten A, Hazen SL, Huang J, Kähönen M, Kyriakou T, Laaksonen R, Lind L, Lindgren C, Magnusson PK, Marouli E, Mihailov E, Morris AP, Nikus K, Pedersen N, Rallidis L, Salomaa V, Shah SH, Stewart AF, Thompson JR, Zalloua PA, Chambers JC, Collins R, Ingelsson E, Iribarren C, Karhunen PJ, Kooner JS, Lehtimäki T, Loos RJ, März W, McPherson R, Metspalu A, Reilly MP, Ripatti S, Sanghera DK, Thiery J, Watkins H, Deloukas P, Kathiresan S, Samani NJ, Schunkert H, Erdmann J, König IR. (2016). No Association of Coronary Artery Disease with X-Chromosomal Variants in Comprehensive International Meta-Analysis. Scientific Reports, 6 (35278 ), 1−9.10.1038/srep35278.
1.1.
2016
Stitziel, Nathan O; Stirrups, Kathleen E; Masca, Nicholas G D; Erdmann, Jeanette; Ferrario, Paola G; König, Inke R; Weeke, Peter E; Webb, Thomas R; Auer, Paul L; Schick, Ursula M; Lu, Yingchang; Zhang, He; Dube, Marie-Pierre; Goel, Anuj; Farrall, Martin; Peloso, Gina M; Won, Hong-Hee; Do, Ron; van Iperen, Erik ... Schunkert, Heribert. (2016). Coding Variation in ANGPTL4, LPL, and SVEP1 and the Risk of Coronary Disease. New England Journal of Medicine, 374 (12), 1134−1144. DOI: 10.1056/NEJMoa1507652.
1.1.
2016
Surendran, Praveen; Drenos, Fotios; Young, Robin; Warren, Helen; Cook, James P; Manning, Alisa K; Grarup, Niels; Sim, Xueling; Barnes, Daniel R; Witkowska, Kate; Staley, James R; Tragante, Vinicius; Tukiainen, Taru; Yaghootkar, Hanieh; Masca, Nicholas; Freitag, Daniel F; Ferreira, Teresa; Giannakopoulou, Olga; Tinker, Andrew; Harakalova, Magdalena ... Munroe, Patricia B (2016). Trans-ancestry meta-analyses identify rare and common variants associated with blood pressure and hypertension. Nature Genetics, 48 (10), 1151−1161. DOI: 10.1038/ng.3654.
1.1.
2016
van der Laan, Sander W.; Fall, Tove; Soumare, Aicha; Teumer, Alexander; Sedaghat, Sanaz; Baumert, Jens; Zabaneh, Delilah; van Setten, Jessica; Isgum, Ivana; Galesloot, Tessel E.; Arpegard, Johannes; Amouyel, Philippe; Trompet, Stella; Waldenberger, Melanie; Doerr, Marcus; Magnusson, Patrik K.; Giedraitis, Vilmantas; Larsson, Anders; Morris, Andrew P.; Felix, Janine F. ... Asselbergs, Folkert W. (2016). Cystatin C and Cardiovascular Disease A Mendelian Randomization Study. Journal of the American College of Cardiology, 68 (9), 934−945.10.1016/j.jacc.2016.05.092.
1.1.
2016
Zondervan, Krina T.; Rahmioglu, Nilufer; Morris, Andrew P.; Nyholt, Dale R.; Montgomery, Grant W.; Becker, Christian M.; Missmer, Stacey A. (2016). Beyond Endometriosis Genome-Wide Association Study: From Genomics to Phenomics to the Patient. Seminars in Reproductive Medicine, 34 (4), 242−254.10.1055/s-0036-1585408.
1.1.
2016
Tyrrell, Jessica; Richmond, Rebecca C.; Palmer, Tom M.; Feenstra, Bjarke; Rangarajan, Janani; Metrustry, Sarah; Cavadino, Alana; Paternoster, Lavinia; Armstrong, Loren L.; De Silva, N. Maneka G.; Wood, Andrew R.; Horikoshi, Momoko; Geller, Frank; Myhre, Ronny; Bradfield, Jonathan P.; Kreiner-Moller, Eskil; Huikari, Ville; Painter, Jodie N.; Hottenga, Jouke-Jan; Allard, Catherine ... Freathy, Rachel M. (2016). Genetic Evidence for Causal Relationships Between Maternal Obesity-Related Traits and Birth Weight. JAMA: the journal of the American Medical Association, 315 (11), 1129−1140.10.1001/jama.2016.1975.
5.1.
2016
Uimari, Outi; Rahmioglu, Nilufer; Nyholt, Dale R.; Becker, Christian M.; Morris, Andrew P.; Montgomery, Grant W.; Zondervan, Krina T. (2016). Genome-Wide Pathway Analysis Highlights the Role of MAPK and Wnt Signaling Pathways in Endometriosis. Reproductive Sciences, 330A−330A.
5.1.
2016
Cook, James P.; Morris, Andrew P. (2016). Investigating Fine-Scale Population Structure in the United Kingdom BioBank. Genetic Epidemiology, 7, 611−612.
6.8.
2016
Knowles, Joshua W.; Xie, Weijia; Zhang, Zhongyang; Chennamsetty, Indumathi; Assimes, Themistocles L.; Paananen, Jussi; Hansson, Ola; Pankow, James; Goodarzi, Mark O.; Carcamo-Orive, Ivan; Morris, Andrew P.; Chen, Yii-Der I.; Maekinen, Ville-Petteri; Ganna, Andrea; Mahajan, Anubha; Guo, Xiuqing; Abbasi, Fahim; Greenawalt, Danielle M.; Lum, Pek; Molony, Cliona ... Quertermous, Thomas (2016). Identification and validation of N-acetyltransferase 2 as an insulin sensitivity gene (vol 125, pg 1, 2015). Journal of Clinical Investigation, 1, 403−403.
6.8.
2016
Stitziel, Nathan O.; Stirrups, Kathleen E.; Masca, Nicholas G. D.; Erdmann, Jeanette; Ferrario, Paola G.; Koenig, Inke R.; Weeke, Peter E.; Webb, Thomas R.; Auer, Paul L.; Schick, Ursula M.; Lu, Yingchang; Zhang, He; Dube, Marie-Pierre; Goel, Anuj; Farrall, Martin; Peloso, Gina M.; Won, Hong-Hee; Do, Ron; van Iperen, Erik; Kanoni, Stavroula ... Schunkert, Heribert (2016). Coding Variation in ANGPTL4, LPL, and SVEP1 and the Risk of Coronary Disease (vol 374, pg 1134, 2016). New England Journal of Medicine, 374 (12, 19), 1898−1898.
1.1.
2015
Horikoshi, M; Mӓgi, R; van, de, Bunt, M; Surakka, I; Sarin, AP; Mahajan, A; Marullo, L; Thorleifsson, G; Hӓgg, S; Hottenga, JJ; Ladenvall, C; Ried, JS; Winkler, TW; Willems, SM; Pervjakova, N; Esko, T; Beekman, M; Nelson, CP; Willenborg, C; Wiltshire, S ... ENGAGE, Consortium. (2015). Discovery and Fine-Mapping of Glycaemic and Obesity-Related Trait Loci Using High-Density Imputation. PLoS Genetics, 11 (7), e1005230. DOI: 10.1371/journal.pgen.1005230.
1.1.
2015
Surakka, I; Horikoshi, M; Mägi, R; Sarin, AP; Mahajan, A; Lagou, V; Marullo, L; Ferreira, T; Miraglio, B; Timonen, S; Kettunen, J; Pirinen, M; Karjalainen, J; Thorleifsson, G; Hägg, S; Hottenga, JJ; Isaacs, A; Ladenvall, C; Beekman, M; Esko, T ... ENGAGE, Consortium. (2015). The impact of low-frequency and rare variants on lipid levels. Nature Genetics, 47 (6), 589−597. DOI: 10.1038/ng.3300.
1.1.
2015
Rahmioglu, N.; Macgregor, S.; Drong, AW.; Hedman, AK.; Harris, HR.; Randall, JC.; Prokopenko, I.; The, International, Endogene, Consortium, (IEC); The, GIANT, Consortium; Nyholt, DR.; Morris, AP.; Montgomery, GW.; Missmer, SA.; Lindgren, CM.; Zondervan, KT.; The, International, Endogene, Consortium, IEC, The, GIANT, Consortium. (2015). Genome-wide enrichment analysis between endometriosis and obesity-related traits reveals novel susceptibility loci. Human Molecular Genetics, 24 (4), 1185−1199. DOI: 10.1093/hmg/ddu516.
1.1.
2015
The, Coffee, and, Caffeine, Genetics, Consortium; Cornelis, MC; Byrne, EM; Esko, T; Nalls, MA; Ganna, A; Paynter, N; Monda, KL; Amin, N; Fischer, K; Renstrom, F; Ngwa, JS; Huikari, V; Cavadino, A; Nolte, IM; Teumer, A; Yu, K; Marques-Vidal, P; Rawal, R; Manichaikul, A ... Chasman, DI. (2015). Genome-wide meta-analysis identifies six novel loci associated with habitual coffee consumption. Molecular Psychiatry, 20 (5), 647−656. DOI: 10.1038/mp.2014.107.
1.1.
2015
Gaulton, Kyle J; Ferreira, Teresa; Lee, Yeji; Raimondo, Anne; Mägi, Reedik; Reschen, Michael E; Mahajan, Anubha; Locke, Adam; Rayner, N William; Robertson, Neil; Scott, Robert A; Prokopenko, Inga; Scott, Laura J; Green, Todd; Sparso, Thomas; Thuillier, Dorothee; Yengo, Loic; Grallert, Harald; Wahl, Simone; Frånberg, Mattias ... , (2015). Genetic fine mapping and genomic annotation defines causal mechanisms at type 2 diabetes susceptibility loci. Nature Genetics, 47 (12), 1415−1425. DOI: 10.1038/ng.3437.
1.1.
2015
Locke, AE.; Kahali, B.; Berndt, SI.; Justice, AE.; Pers, TH.; Day, FR.; Powell, C.; Vedantam, S.; Buchkovich, ML.; Yang, J.; Croteau-Chonka, DC.; Esko, T.; Fall, T.; Ferreira, T.; Gustafsson, S.; Kutalik, Z.; Luan, J.; Mägi, R.; Randall, JC.; Winkler, TW. ... Speliotes, EK. (2015). Genetic studies of body mass index yield new insights for obesity biology. Nature, 518 (7538), 197−206. DOI: 10.1038/nature14177.
1.1.
2015
Shungin, D; Winkler, TW; Croteau-Chonka, DC; Ferreira, T; Locke, AE; Mägi, R; Strawbridge, RJ; Pers, TH; Fischer, K; Justice, AE; Workalemahu, T; Wu, JM; Buchkovich, ML; Heard-Costa, NL; Roman, TS; Drong, AW; Song, C; Gustafsson, S; Day, FR; Esko, T ... Mohlke, KL. (2015). New genetic loci link adipose and insulin biology to body fat distribution. Nature, 518 (7538), 187−196. DOI: 10.1038/nature14132.
1.1.
2015
Nikpay, M; Goel, A; Won, HH; Hall, LM; Willenborg, C; Kanoni, S; Saleheen, D; Kyriakou, T; Nelson, CP; Hopewell, JC; Webb, TR; Zeng, L; Dehghan, A; Alver, M; Armasu, SM; Auro, K; Bjonnes, A; Chasman, DI; Chen, S; Ford, I ... Farrall, M. (2015). A comprehensive 1000 Genomes–based genome-wide association meta-analysis of coronary artery disease. Nature Genetics, 47 (10), 1121−1130. DOI: 10.1038/ng.3396.
1.1.
2015
Wain, LV; Shrine, N; Miller, S; Jackson, VE; Ntalla, I; Artigas, MS; Billington, CK; Kheirallah, AK; Allen, R; Cook, JP; Probert, K; Obeidat, M; Bosse, Y; Hao, K; Postma, DS; Pare, PD; Ramasamy, A; Magi, R; Mihailov, E; Reinmaa, E Melen, E ... Hall, IP (2015). Novel insights into the genetics of smoking behaviour, lung function, and chronic obstructive pulmonary disease (UK BiLEVE): a genetic association study in UK Biobank. The Lancet Respiratory Medicine, 3 (10), 769−781.10.1016/S2213-2600(15)00283-0.
1.1.
2015
Lunetta, KL; Day, FR; Sulem, P; Ruth, KS; Tung, JY; Hinds, DA; Esko, T; Elks, CE; Altmaier, E; He, C; Huffman, JE; Mihailov, E; Porcu, E; Robino, A; Rose, LM; Schick, UM; Stolk, L; Teumer, A; Thompson, DJ; Traglia, M ... Perry, JR. (2015). Rare coding variants and X-linked loci associated with age at menarche. Nature Communications, 6 (7756), 1−7. DOI: 10.1038/ncomms8756.
1.1.
2015
Joshi, Peter K.; Esko, Tõnu; Mattsson, Hannele; Eklund, Niina; Gandin, Ilaria; Nutile, Teresa; Jackson, Anne U.; Schurmann, Claudia; Smith, Albert V.; Zhang, Weihua; Okada, Yukinori; Stancakova, Alena; Faul, Jessica D.; Zhao, Wei; Bartz, Traci M.; Concas, Maria Pina; Franceschini, Nora; Enroth, Stefan; Vitart, Veronique; Trompet, Stella ... Wilson, James F. (2015). Directional dominance on stature and cognition in diverse human populations. Nature, 523 (7561), 459−476. DOI: 10.1038/nature14618.
1.1.
2015
Asimit, Jennifer L.; Panoutsopoulou, Kalliope; Wheeler, Eleanor; Berndt, Sonja I.; Cordell, Heather J.; Morris, Andrew P.; Zeggini, Eleftheria; Barroso, Ines (2015). A Bayesian Approach to the Overlap Analysis of Epidemiologically Linked Traits. Genetic Epidemiology, 39 (8), 624−634.10.1002/gepi.21919.
1.1.
2015
Artigas, Maria Soler; Wain, Louise V.; Miller, Suzanne; Kheirallah, Abdul Kader; Huffman, Jennifer E.; Ntalla, Ioanna; Shrine, Nick; Obeidat, Ma'en; Trochet, Holly; McArdle, Wendy L.; Alves, Alexessander Couto; Hui, Jennie; Zhao, Jing Hua; Joshi, Peter K.; Teumer, Alexander; Albrecht, Eva; Imboden, Medea; Rawal, Rajesh; Lopez, Lorna M.; Marten, Jonathan ... Zeggini, Eleftheria (2015). Sixteen new lung function signals identified through 1000 Genomes Project reference panel imputation. Nature Communications, 6 (8658), 1−12.10.1038/ncomms9658.
1.1.
2015
van de Bunt, Martijn; Cortes, Adrian; Brown, Matthew A.; Morris, Andrew P.; McCarthy, Mark I. (2015). Evaluating the Performance of Fine-Mapping Strategies at Common Variant GWAS Loci. PLoS Genetics, 11 (9), ARTN e1005535.10.1371/journal.pgen.1005535.
1.1.
2015
Lu, Yi; Cuellar-Partida, Gabriel; Painter, Jodie N.; Nyholt, Dale R.; Morris, Andrew P.; Fasching, Peter A.; Hein, Alexander; Burghaus, Stefanie; Beckmann, Matthias W.; Lambrechts, Diether; Van Nieuwenhuysen, Els; Vergote, Ignace; Vanderstichele, Adriaan; Doherty, Jennifer Anne; Rossing, Mary Anne; Wicklund, Kristine G.; Chang-Claude, Jenny; Eilber, Ursula; Rudolph, Anja; Wang-Gohrke, Shan ... MacGregor, Stuart (2015). Shared genetics underlying epidemiological association between endometriosis and ovarian cancer. Human Molecular Genetics, 24 (20), 5955−5964.10.1093/hmg/ddv306.
1.1.
2015
Liu, Jimmy Z.; van Sommeren, Suzanne; Huang, Hailiang; Ng, Siew C.; Alberts, Rudi; Takahashi, Atsushi; Ripke, Stephan; Lee, James C.; Jostins, Luke; Shah, Tejas; Abedian, Shifteh; Cheon, Jae Hee; Cho, Judy; Daryani, Naser E.; Franke, Lude; Fuyuno, Yuta; Hart, Ailsa; Juyal, Ramesh C.; Juyal, Garima; Kim, Won Ho ... Weersma, Rinse K. (2015). Association analyses identify 38 susceptibility loci for inflammatory bowel disease and highlight shared genetic risk across populations. Nature Genetics, 47 (9), 979−990.10.1038/ng.3359.
1.1.
2015
Boukari, Yamina; Scurr, David J.; Qutachi, Omar; Morris, Andrew P.; Doughty, Stephen W.; Rahman, Cheryl V.; Billa, Nashiru (2015). Physicomechanical properties of sintered scaffolds formed from porous and protein-loaded poly(DL-lactic-co-glycolic acid) microspheres for potential use in bone tissue engineering. Journal of Biomaterials Science Polymer Edition, 26 (12), 796−811.10.1080/09205063.2015.1058696.
1.1.
2015
Ng, Esther; Salihovic, Samira; Lind, P. Monica; Mahajan, Anubha; Syvanen, Anne-Christine; Axelsson, Tomas; Ingelsson, Erik; Lindgren, Cecilia M.; van Bavel, Bert; Morris, Andrew P.; Lind, Lars (2015). Genome-wide association study of plasma levels of polychlorinated biphenyls disclose an association with the CYP2B6 gene in a population-based sample. Environmental Research, 140, 95−101.10.1016/j.envres.2015.03.022.
1.1.
2015
Sapkota, Yadav; Attia, John; Gordon, Scott D.; Henders, Anjali K.; Holliday, Elizabeth G.; Rahmioglu, Nilufer; MacGregor, Stuart; Martin, Nicholas G.; McEvoy, Mark; Morris, Andrew P.; Scott, Rodney J.; Zondervan, Krina T.; Montgomery, Grant W.; Nyholt, Dale R. (2015). Genetic burden associated with varying degrees of disease severity in endometriosis. Molecular Human Reproduction, 21 (7), 594−602.10.1093/molehr/gav021.
1.1.
2015
Knowles, Joshua W.; Xie, Weijia; Zhang, Zhongyang; Chennemsetty, Indumathi; Assimes, Themistocles L.; Paananen, Jussi; Hansson, Ola; Pankow, James; Goodarzi, Mark O.; Carcamo-Orive, Ivan; Morris, Andrew P.; Chen, Yii-Der I.; Maekinen, Ville-Petteri; Ganna, Andrea; Mahajan, Anubha; Guo, Xiuqing; Abbasi, Fahim; Greenawalt, Danielle M.; Lum, Pek; Molony, Cliona ... Quertermous, Thomas (2015). Identification and validation of N-acetyltransferase 2 as an insulin sensitivity gene. Journal of Clinical Investigation, 125 (4), 1739−1751. DOI: 10.1172/JCI74692.
1.1.
2015
den Hoed, Marcel; Strawbridge, Rona J.; Almgren, Peter; Gustafsson, Stefan; Axelsson, Tomas; Engstrom, Gunnar; de Faire, Ulf; Hedblad, Bo; Humphries, Steve E.; Lindgren, Cecilia M.; Morris, Andrew P.; Ostling, Gerd; Syvanen, Ann-Christine; Tremoli, Elena; Hamsten, Anders; Ingelsson, Erik; Melander, Olle; Lind, Lars (2015). GWAS-identified loci for coronary heart disease are associated with intima-media thickness and plaque presence at the carotid artery bulb. Atherosclerosis, 239 (20), 304−310.10.1016/j.atherosclerosis.2015.01.032.
1.1.
2015
Mahajan, Anubha; Sim, Xueling; Ng, Hui Jin; Manning, Alisa; Rivas, Manuel A.; Highland, Heather M.; Locke, Adam E.; Grarup, Niels; Im, Hae Kyung; Cingolani, Pablo; Flannick, Jason; Fontanillas, Pierre; Fuchsberger, Christian; Gaulton, Kyle J.; Teslovich, Tanya M.; Rayner, N. William; Robertson, Neil R.; Beer, Nicola L.; Rundle, Jana K.; Bork-Jensen, Jette ... Gloyn, Anna L. (2015). Identification and Functional Characterization of G6PC2 Coding Variants Influencing Glycemic Traits Define an Effector Transcript at the G6PC2-ABCB11 Locus. PLoS Genetics, 11 (1), ARTN e1004876.10.1371/journal.pgen.1004876.
1.1.
2015
Sapkota, Yadav; Low, Siew-Kee; Attia, John; Gordon, Scott D.; Henders, Anjali K.; Holliday, Elizabeth G.; MacGregor, Stuart; Martin, Nicholas G.; McEvoy, Mark; Morris, Andrew P.; Takahashi, Atsushi; Scott, Rodney J.; Kubo, Michiaki; Zondervan, Krina T.; Montgomery, Grant W.; Nyholt, Dale R. (2015). Association between endometriosis and the interleukin 1A (ILIA) locus. Human Reproduction, 30 (1), 239−248.10.1093/humrep/deu267.
1.1.
2015
Ng, Esther; Lind, P. Monica; Lindgren, Cecilia; Ingelsson, Erik; Mahajan, Anubha; Morris, Andrew; Lind, Lars (2015). Genome-wide association study of toxic metals and trace elements reveals novel associations. Human Molecular Genetics, 24 (16), 4739−4745.10.1093/hmg/ddv190.
1.1.
2015
Dumanski, Jan P.; Rasi, Chiara; Lonn, Mikael; Davies, Hanna; Ingelsson, Martin; Giedraitis, Vilmantas; Lannfelt, Lars; Magnusson, Patrik K. E.; Lindgren, Cecilia M.; Morris, Andrew P.; Cesarini, David; Johannesson, Magnus; Janson, Eva Tiensuu; Lind, Lars; Pedersen, Nancy L.; Ingelsson, Erik; Forsberg, Lars A. (2015). Smoking is associated with mosaic loss of chromosome Y. Science, 347 (6217), 81−83.10.1126/science.1262092.
1.1.
2015
Winkler, Thomas W.; Justice, Anne E.; Graff, Mariaelisa; Barata, Llilda; Feitosa, Mary F.; Chu, Su; Czajkowski, Jacek; Esko, Tonu; Fall, Tove; Kilpelainen, Tuomas O.; Lu, Yingchang; Magi, Reedik; Mihailov, Evelin; Pers, Tune H.; Rueeger, Sina; Teumer, Alexander; Ehret, Georg B.; Ferreira, Teresa; Heard-Costa, Nancy L.; Karjalainen, Juha ... Loos, Ruth J. F. (2015). The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study. PLoS Genetics, 11 (10), ARTN e1005378.10.1371/journal.pgen.1005378.
5.1.
2015
Kaakinen, M.; Maegi, R.; Fischer, K.; Jarvelin, M. -R.; Morris, A. P.; Prokopenko, I. (2015). A Novel Method and Software Tool for Genome-Wide Multi-Phenotype Analysis of Rare Variants. Human Heredity, 79: 43rd European Mathematical Genetics Meeting (EMGM), Brest, FRANCE, APR 16-17, 2015. Karger, 39−39. (1).
5.1.
2015
Dumanski, Jan P.; Rasi, Chiara; Lonn, Mikael; Davies, Hanna; Ingelsson, Martin; Giedraitis, Vilmantas; Lannfelt, Lars; Magnusson, Patrik K. E.; Lindgren, Cecilia M.; Morris, Andrew P.; Cesarini, David; Johannesson, Magnus; Janson, Eva Tiensuu; Lind, Lars; Pedersen, Nancy L.; Ingelsson, Erik; Forsberg, Lars A. (2015). Smoking is associated with mosaic loss of chromosome Y. Cancer Research, 75, 4683. DOI: 10.1158/1538-7445.AM2015-4683.
5.1.
2015
Kaakinen, Marika; Magi, Reedik; Fischer, Krista; Jarvelin, Marjo-Riitta; Morris, Andrew P.; Prokopenko, Inga (2015). MARV: Anovel method and software tool for genome-wide multi-phenotype analysis of rare variants. BMC Bioinformatics, 18 (1), 560−560. DOI: 10.1186/s12859-017-1530-2.
5.1.
2015
Cook, James P.; Morris, Andrew P. (2015). Methodology for the analysis of multi-ethnic genome-wide association studies. Genetic Epidemiology, 39 (7), 540−541.
5.1.
2015
Allen, Richard J.; Wain, Louise V.; Shrine, Nick; Miller, Suzanne; Jackson, Victoria E.; Ntalla, Ioanna; Artigas, Maria Soler; Cook, James P.; Morris, Andrew P.; Zeggini, Eleftheria; Marchini, Jonathan; De-Loukas, Panos; Hansell, Anna; Hubbard, Richard; Pavord, Ian; Thompson, Neil C.; Strachan, David P.; Hall, Ian P.; Tobin, Martin D. (2015). Shared polygenic effects of FEV1 in the first genetic study in UK Biobank. Genetic Epidemiology, 39 (7), 529−530.
5.1.
2015
Raghavan, Sridharan; Hong, Jaeyoung; Hara, Kazuo; Maruthur, Nisa M.; Lipovich, Leonard; Guo, Xiuqing; Florez, Jose C.; Loos, Ruth J. F.; Dupuis, Josee; Liu, Ching-Ti; Morris, Andrew P.; Meigs, James B. (2015). Trans-ethnic Fine-Mapping Implicates Regulatory Variation at Glycemic Quantitative Trait Loci: The African-American Glucose and Insulin Genetic Epidemiology (AAGILE) Consortium. Diabetes, 64 (1, Supplement ), A455−A456.
5.1.
2015
Horikoshi, Momoko; Carstensen, Lisbeth; Strachan, David P.; Kooijman, Marjolein N.; Boh, Eileen T. H.; Joshi, Peter K.; Van Leeuwen, Elisabeth M.; Bradfield, Jonathan P.; Pitkaenen, Niina; Lyytikaeinen, Leo-Pekka; Lindi, Virpi; Joro, Raimo; Kreiner-Moller, Eskil; Thiering, Elisabeth; Rueedi, Rico; Ang, Wei; Wang, Carol; Ntalla, Ioanna; Wu, Ying; Vilortejedor, Natalia ... Morris, Andrew P. (2015). Large Scale Genome-Wide Association Study for Birth Weight Finds Eight Novel Loci Extending the Genetic Link between Early Growth and Type 2 Diabetes. Diabetes, 64 (1, Supplement ), A6−A7.
5.1.
2015
Magi, Reedik; Scott, Robert A.; Morris, Andrew P.; Marullo, Letizia; Gaulton, Kyle; Boehnke, Michael; Dupuis, Josee; Mccarthy, Mark I.; Scott, Laura J.; Prokopenko, Inga (2015). Genome-Wide Association Study Imputed to 1000 Genomes Project Reference Panels Reveals 17 Novel Associations with Type 2 Diabetes. Diabetes, 64 (1, Supplement ), A5−A5.
5.1.
2015
Yin, Peng; Jorgensen, Andrea; Morris, Andrew P.; Turner, Richard; Fitzgerald, Richard; Stables, Rod; Hanson, Anita; Pirmohamed, Munir (2015). Pharmacogenetics of Acute Coronary Syndrome. Genetic Epidemiology, 39 (7), 596−596.
6.8.
2015
Morris, Andrew P. (2015). Fine Mapping of Type 2 Diabetes Susceptibility Loci (vol 14, 549, 2014). Current Diabetes Reports, 15 (1), UNSP 575. DOI: 10.1007/s11892-014-0575-0.
1.1.
2014
Winkler, T.W.; Day, FR.; Croteau-Chonka, DC.; Wood, AR.; Locke, AE.; Magi, R.; Ferreira, T.; Fall, T.; Graff, M.; Justice, AE.; Luan, JA.; Gustafsson, S.; Randall, JC.; Vedantam, S.; Workalemahu, T.; Kilpelainen, TO.; Scherag, A.; Esko, T.; Kutalik, Z.; Heid, IM. ... Loos, RJF (2014). Quality control and conduct of genome-wide association meta-analyses. Nature Protocols, 9 (5), 1192−1212. DOI: 10.1038/nprot.2014.071.
1.1.
2014
Wood, AR; Esko, T; Yang, J; Vedantam, S; Pers, TH; Gustafsson, S; Chu, AY; Estrada, K; Luan, J; Kutalik, Z; Amin, N; Buchkovich, ML; Croteau-Chonka, DC; Day, FR; Duan, Y14; Fall, T; Fehrmann, R; Ferreira, T; Jackson, AU; Karjalainen, J ... Frayling, TM. (2014). Defining the role of common variation in the genomic and biological architecture of adult human height. Nature Genetics, 46 (11), 1173−1186. DOI: 10.1038/ng.3097.
1.1.
2014
Yuan, Wei; Xia, Yudong; Bell, Christopher G.; Yet, Idil; Ferreira, Teresa; Ward, Kirsten J.; Gao, Fei; Loomis, A. Katrina; Hyde, Craig L.; Wu, Honglong; Lu, Hanlin; Liu, Yuan; Small, Kerrin S.; Vinuela, Ana; Morris, Andrew P.; Berdasco, Maria; Esteller, Manel; Brosnan, M. Julia; Deloukas, Panos; McCarthy, Mark I. ... Spector, Tim D. (2014). An integrated epigenomic analysis for type 2 diabetes susceptibility loci in monozygotic twins. Nature Communications, 5, ARTN 5719.10.1038/ncomms6719.
1.1.
2014
Keller, Margaux F.; Reiner, Alexander P.; Okada, Yukinori; van Rooij, Frank J. A.; Johnson, Andrew D.; Chen, Ming-Huei; Smith, Albert V.; Morris, Andrew P.; Tanaka, Toshiko; Ferrucci, Luigi; Zonderman, Alan B.; Lettre, Guillaume; Harris, Tamara; Garcia, Melissa; Bandinelli, Stefania; Qayyum, Rehan; Yanek, Lisa R.; Becker, Diane M.; Becker, Lewis C.; Kooperberg, Charles ... Nalls, Mike A. (2014). Trans-ethnic meta-analysis of white blood cell phenotypes. Human Molecular Genetics, 23 (25), 6944−6960.10.1093/hmg/ddu401.
1.1.
2014
Moutsianas, Loukas; Morris, Andrew P. (2014). Methodology for the analysis of rare genetic variation in genome-wide association and re-sequencing studies of complex human traits. Briefings in Functional Genomics, 13 (5), 362−370.10.1093/bfgp/elu012.
1.1.
2014
Xi, Bo; Takeuchi, Fumihiko; Meirhaeghe, Aline; Kato, Norihiro; Chambers, John C.; Morris, Andrew P.; Cho, Yoon Shin; Zhang, Weihua; Mohlke, Karen L.; Kooner, Jaspal S.; Shu, Xiao Ou; Pan, Hongwei; Tai, E. Shyong; Pan, Haiyan; Wu, Jer-Yuarn; Zhou, Donghao; Chandak, Giriraj R. (2014). Associations of genetic variants in/near body mass index-associated genes with type 2 diabetes: a systematic meta-analysis. Clinical Endocrinology, 81 (5), 702−710.10.1111/cen.12428.
1.1.
2014
Rahmioglu, Nilufer; Nyholt, Dale R.; Morris, Andrew P.; Missmer, Stacey A.; Montgomery, Grant W.; Zondervan, Krina T. (2014). Genetic variants underlying risk of endometriosis: insights from meta-analysis of eight genome-wide association and replication datasets. Human Reproduction Update, 20 (5), 702−716.10.1093/humupd/dmu015.
1.1.
2014
Tang, Wenbo; Kowgier, Matthew; Loth, Daan W.; Artigas, Maria Soler; Joubert, Bonnie R.; Hodge, Emily; Gharib, Sina A.; Smith, Albert V.; Ruczinski, Ingo; Gudnason, Vilmundur; Mathias, Rasika A.; Harris, Tamara B.; Hansel, Nadia N.; Launer, Lenore J.; Barnes, Kathleen C.; Hansen, Joyanna G.; Albrecht, Eva; Aldrich, Melinda C.; Allerhand, Michael; Barr, R. Graham ... Cassano, Patricia A. (2014). Large-Scale Genome-Wide Association Studies and Meta-Analyses of Longitudinal Change in Adult Lung Function. PLoS ONE, 9 (7), ARTN e100776.10.1371/journal.pone.0100776.
1.1.
2014
Lind, Lars; Penell, Johanna; Syvaenen, Anne-Christine; Axelsson, Tomas; Ingelsson, Erik; Morris, Andrew P.; Lindgren, Cecilia; Salihovic, Samira; van Bavel, Bert; Lind, P. Monica (2014). Genetic variation in the CYP1A1 gene is related to circulating PCB118 levels in a population-based sample. Environmental Research, 133, 135−140.10.1016/j.envres.2014.05.017.
1.1.
2014
Langenberg, Claudia; Sharp, Stephen J.; Franks, Paul W.; Scott, Robert A.; Deloukas, Panos; Forouhi, Nita G.; Froguel, Philippe; Groop, Leif C.; Hansen, Torben; Palla, Luigi; Pedersen, Oluf; Schulze, Matthias B.; Tormo, Maria-Jose; Wheeler, Eleanor; Agnoli, Claudia; Arriola, Larraitz; Barricarte, Aurelio; Boeing, Heiner; Clarke, Geraldine M.; Clavel-Chapelon, Francoise ... Wareham, Nicholas J. (2014). Gene-Lifestyle Interaction and Type 2 Diabetes: The EPIC InterAct Case-Cohort Study. PLoS Medicine, 11 (5), ARTN e1001647.10.1371/journal.pmed.1001647.
1.1.
2014
Loth, Daan W.; Artigas, Maria Soler; Gharib, Sina A.; Wain, Louise V.; Franceschini, Nora; Koch, Beate; Pottinger, Tess D.; Smith, Albert Vernon; Duan, Qing; Oldmeadow, Chris; Lee, Mi Kyeong; Strachan, David P.; James, Alan L.; Huffman, Jennifer E.; Vitart, Veronique; Ramasamy, Adaikalavan; Wareham, Nicholas J.; Kaprio, Jaakko; Wang, Xin-Qun; Trochet, Holly ... London, Stephanie J. (2014). Genome-wide association analysis identifies six new loci associated with forced vital capacity. Nature Genetics, 46 (7), 669−677.10.1038/ng.3011.
1.1.
2014
Penell, Johanna; Lind, Lars; Fall, Tove; Syvanen, Anne-Christine; Axelsson, Tomas; Lundmark, Per; Morris, Andrew P.; Lindgren, Cecilia; Mahajan, Anubha; Salihovic, Samira; van Bavel, Bert; Ingelsson, Erik; Lind, P. Monica (2014). Genetic variation in the CYP2B6 Gene is related to circulating 2,2 ',4,4 '-tetrabromodiphenyl ether (BDE-47) concentrations: an observational population-based study. Environmental Health, 13 (1), ARTN 34.10.1186/1476-069X-13-34.
1.1.
2014
Forsberg, Lars A.; Rasi, Chiara; Malmqvist, Niklas; Davies, Hanna; Pasupulati, Saichand; Pakalapati, Geeta; Sandgren, Johanna; de Stahl, Teresita Diaz; Zaghlool, Ammar; Giedraitis, Vilmantas; Lannfelt, Lars; Score, Joannah; Cross, Nicholas C. P.; Absher, Devin; Janson, Eva Tiensuu; Lindgren, Cecilia M.; Morris, Andrew P.; Ingelsson, Erik; Lind, Lars; Dumanski, Jan P. (2014). Mosaic loss of chromosome Y in peripheral blood is associated with shorter survival and higher risk of cancer. Nature Genetics, 46 (6), 624−628.10.1038/ng.2966.
1.1.
2014
Flannick, Jason; Thorleifsson, Gudmar; Beer, Nicola L.; Jacobs, Suzanne B. R.; Grarup, Niels; Burtt, Noel P.; Mahajan, Anubha; Fuchsberger, Christian; Atzmon, Gil; Benediktsson, Rafn; Blangero, John; Bowden, Don W.; Brandslund, Ivan; Brosnan, Julia; Burslem, Frank; Chambers, John; Cho, Yoon Shin; Christensen, Cramer; Douglas, Desiree A.; Duggirala, Ravindranath ... Altshuler, David (2014). Loss-of-function mutations in SLC30A8 protect against type 2 diabetes. Nature Genetics, 46 (4), 357−365.10.1038/ng.2915.
1.1.
2014
Bolton, Jennifer L.; Hayward, Caroline; Direk, Nese; Lewis, John G.; Hammond, Geoffrey L.; Hill, Lesley A.; Anderson, Anna; Huffman, Jennifer; Wilson, James F.; Campbell, Harry; Rudan, Igor; Wright, Alan; Hastie, Nicholas; Wild, Sarah H.; Velders, Fleur P.; Hofman, Albert; Uitterlinden, Andre G.; Lahti, Jari; Raikkonen, Katri; Kajantie, Eero ... Walker, Brian R. (2014). Genome Wide Association Identifies Common Variants at the SERPINA6/SERPINA1 Locus Influencing Plasma Cortisol and Corticosteroid Binding Globulin. PLoS Genetics, 10 (7), ARTN e1004474.10.1371/journal.pgen.1004474.
1.1.
2014
Kraja, Aldi T.; Chasman, Daniel I.; North, Kari E.; Reiner, Alexander P.; Yanek, Lisa R.; Kilpelainen, Tuomas O.; Smith, Jennifer A.; Dehghan, Abbas; Dupuis, Josee; Johnson, Andrew D.; Feitosa, Mary F.; Tekola-Ayele, Fasil; Chu, Audrey Y.; Nolte, Ilja M.; Dastani, Zari; Morris, Andrew; Pendergrass, Sarah A.; Sun, Yan V.; Ritchie, Marylyn D.; Vaez, Ahmad ... Borecki, Ingrid B. (2014). Pleiotropic genes for metabolic syndrome and inflammation. Molecular Genetics and Metabolism, 112 (4), 317−338.10.1016/j.ymgme.2014.04.007.
1.1.
2014
Mägi, Reedik; Metspalu, Andres; Mihailov, Evelin (2014). Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility. Nature Genetics, 46 (3), 234−244. DOI: 10.1038/ng.2897.
1.1.
2014
Becker, Jessica; Czamara, Darina; Scerri, Tom S.; Ramus, Franck; Csepe, Valeria; Talcott, Joel B.; Stein, John; Morris, Andrew; Ludwig, Kerstin U.; Hoffmann, Per; Honbolygo, Ferenc; Toth, Denes; Fauchereau, Fabien; Bogliotti, Caroline; Iannuzzi, Stephanie; Chaix, Yves; Valdois, Sylviane; Billard, Catherine; George, Florence; Soares-Boucaud, Isabelle ... Schumacher, Johannes (2014). Genetic analysis of dyslexia candidate genes in the European cross-linguistic NeuroDys cohort. European Journal of Human Genetics, 22 (5), 675−680.10.1038/ejhg.2013.199.
1.2.
2014
Morris, AP. (2014). Fine Mapping of Type 2 Diabetes Susceptibility Loci. Current Diabetes Reports, 14 (549), 1−8.10.1007/s11892-014-0549-2.
5.1.
2014
Morris, A. P.; Teslovich, T. M.; Ferreira, T.; Mahajan, A.; Lee, Y.; Rayner, N. W.); Magi, R. (2014). Fine-mapping type 2 diabetes susceptibility loci with high-density imputation. DIABETOLOGIA, 57: 50th EASD Annual Meeting, Vienna, Austria, 15-19.09.2014. Springer, S50−S51.
1.1.
2013
Fall, T.; Hagg, S.; Magi, R.; Ploner, A.; Fischer, K.; Horikoshi, M.; Sarin, AP.; Thorleifsson, G.; Ladenvall, C.; Kals, M.; Kuningas, M.; Draisma, HHM.; Ried, JS.; van Zuydam, NR.; Huikari, V.; Mangino, M.; Sonestedt, E.; Benyamin, B.; Nelson, CP.; Rivera, NV. ... Prokopenko, I. (2013). The Role of Adiposity in Cardiometabolic Traits: A Mendelian Randomization Analysis. PLoS Medicine, 10 (6), e1001474−e1001474. DOI: 10.1371/journal.pmed.1001474.
1.1.
2013
Deloukas, P; Kanoni, S; Willenborg, C; Farrall, M; Assimes, TL; Thompson, JR; Ingelsson, E; Saleheen, D; Erdmann, J; Goldstein, BA; Stirrups, K; König, IR; Cazier, JB; Johansson, A; Hall, AS; Lee, JY; Willer, CJ; Chambers, JC; Esko, T; Folkersen, L ... Samani, NJ (2013). Large-scale association analysis identifies new risk loci for coronary artery disease. Nature Genetics, 45 (1), 25−33. DOI: 10.1038/ng.2480.
1.1.
2013
Vimaleswaran, KS.; Berry, DJ.; Lu, C.; Tikkanen, E.; Pilz, S.; Hiraki, LT.; Cooper, JD.; Dastani, Z.; Li, R.; Houston, DK.; Wood, AR.; Michaëlsson, K.; Vandenput, L.; Zgaga, L.; Yerges-Armstrong, LM.; McCarthy, MI.; Dupuis, J.; Kaakinen, M.; Kleber, ME.; Jameson, K. ... Hyppönen, E. (2013). Causal relationship between obesity and vitamin D status: bi-directional Mendelian randomization analysis of multiple cohorts. PLoS Medicine, 10 (2), e1001383. DOI: 10.1371/journal.pmed.1001383.
1.1.
2013
Do, R; Willer, CJ; Schmidt, EM; Sengupta, S; Gao, C; Peloso, GM; Gustafsson, S; Kanoni, S; Ganna, A; Chen, J; Buchkovich, ML; Mora, S; Beckmann, JS; Bragg-Gresham, JL; Chang, HY; Demirkan, A; Den, Hertog, HM; Donnelly, LA; Ehret, GB; Esko, T ... Kathiresan, S. (2013). Common variants associated with plasma triglycerides and risk for coronary artery disease. Nature Genetics, 45 (11), 1345−1352 . DOI: 10.1038/ng.2795.
1.1.
2013
Global, Lipids, Genetics, Consortium; Willer, CJ; Schmidt, EM; Sengupta, S; Peloso, GM; Gustafsson, S; Kanoni, S; Ganna, A; Chen, J; Buchkovich, ML; Mora, S; Beckmann, JS; Bragg-Gresham, JL; Chang, HY; Demirkan, A; Den, Hertog, HM; Do, R; Donnelly, LA; Ehret, GB; Esko, T ... Abecasis, GR. (2013). Discovery and refinement of loci associated with lipid levels. Nature Genetics, 45 (11), 1274−1283. DOI: 10.1038/ng.2797.
1.1.
2013
Berndt, SI; Gustafsson, S; Mägi, R; Ganna, A; Wheeler, E; Feitosa, MF; Justice, AE; Monda, KL; Croteau-Chonka, DC; Day, FR; Esko, T; Fall, T; Ferreira, T; Gentilini, D; Jackson, AU; Luan, J; Randall, JC; Vedantam, S; Willer, CJ; Winkler, TW ... Ingelsson, E. (2013). Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture. Nature Genetics, 45 (5), 501−U69. DOI: 10.1038/ng.2606.
1.1.
2013
den Hoed, M; Eijgelsheim, M; Esko, T; Brundel, BJ; Peal, DS; Evans, DM; Nolte, IM; Segrè, AV; Holm, H; Handsaker, RE; Westra, HJ; Johnson, T; Isaacs, A; Yang, J; Lundby, A; Zhao, JH; Kim, YJ; Go, MJ; Almgren, P; Bochud, M ... Loos, RJ. (2013). Identification of heart rate-associated loci and their effects on cardiac conduction and rhythm disorders. Nature Genetics, 45 (6), 621.
1.1.
2013
Randall, JC; Winkler, TW; Kutalik, Z; Berndt, SI; Jackson, AU; Monda, KL; Kilpeläinen, TO; Esko, T; Mägi, R; Li, S; Workalemahu, T; Feitosa, MF; Croteau-Chonka, DC; Day, FR; Fall, T; Ferreira, T; Gustafsson, S; Locke, AE; Mathieson, I; Scherag, A ... Heid, IM (2013). Sex-stratified Genome-wide Association Studies Including 270,000 Individuals Show Sexual Dimorphism in Genetic Loci for Anthropometric Traits. PLoS Genetics, 9 (6), e1003500. DOI: 10.1371/journal.pgen.1003500.
1.1.
2013
Brandler, William M.; Morris, Andrew P.; Evans, David M.; Scerri, Thomas S.; Kemp, John P.; Timpson, Nicholas J.; St Pourcain, Beate; Smith, George Davey; Ring, Susan M.; Stein, John; Monaco, Anthony P.; Talcott, Joel B.; Fisher, Simon E.; Webber, Caleb; Paracchini, Silvia (2013). Common Variants in Left/Right Asymmetry Genes and Pathways Are Associated with Relative Hand Skill. PLoS Genetics, 9 (9), ARTN e1003751.10.1371/journal.pgen.1003751.
1.1.
2013
O'Seaghdha, Conall M.; Wu, Hongsheng; Yang, Qiong; Kapur, Karen; Guessous, Idris; Zuber, Annie Mercier; Koettgen, Anna; Stoudmann, Candice; Teumer, Alexander; Kutalik, Zoltan; Mangino, Massimo; Dehghan, Abbas; Zhang, Weihua; Eiriksdottir, Gudny; Li, Guo; Tanaka, Toshiko; Portas, Laura; Lopez, Lorna M.; Hayward, Caroline; Lohman, Kurt ... Bochud, Murielle (2013). Meta-Analysis of Genome-Wide Association Studies Identifies Six New Loci for Serum Calcium Concentrations. PLoS Genetics, 9 (9), ARTN e1003796.10.1371/journal.pgen.1003796.
1.1.
2013
Clarke, Geraldine M.; Rivas, Manuel A.; Morris, Andrew P. (2013). A Flexible Approach for the Analysis of Rare Variants Allowing for a Mixture of Effects on Binary or Quantitative Traits. PLoS Genetics, 8, ARTN e1003694.10.1371/journal.pgen.1003694.
1.1.
2013
Lam, Vincent Kwok Lim; Ma, Ronald Ching Wan; Lee, Heung Man; Hu, Cheng; Park, Kyong Soo; Furuta, Hiroto; Wang, Ying; Tam, Claudia Ha Ting; Sim, Xueling; Ng, Daniel Peng-Keat; Liu, Jianjun; Wong, Tien-Yin; Tai, E. Shyong; Morris, Andrew P.; Tang, Nelson Leung Sang; Woo, Jean; Leung, Ping Chung; Kong, Alice Pik Shan; Ozaki, Risa; Jia, Wei Ping ... Chan, Juliana Chung Ngor (2013). Genetic Associations of Type 2 Diabetes with Islet Amyloid Polypeptide Processing and Degrading Pathways in Asian Populations. PLoS ONE, 8 (6), ARTN e62378.10.1371/journal.pone.0062378.
1.1.
2013
Saxena, Richa; Saleheen, Danish; Been, Latonya F.; Garavito, Martha L.; Braun, Timothy; Bjonnes, Andrew; Young, Robin; Ho, Weang Kee; Rasheed, Asif; Frossard, Philippe; Sim, Xueling; Hassanali, Neelam; Radha, Venkatesan; Chidambaram, Manickam; Liju, Samuel; Rees, Simon D.; Ng, Daniel Peng-Keat; Wong, Tien-Yin; Yamauchi, Toshimasa; Hara, Kazuo ... Sanghera, Dharambir K. (2013). Genome-Wide Association Study Identifies a Novel Locus Contributing to Type 2 Diabetes Susceptibility in Sikhs of Punjabi Origin From India. Diabetes, 62 (5), 1746−1755.10.2337/db12-1077.
1.1.
2013
Travers, Mary E.; Mackay, Deborah J. G.; Nitert, Marloes Dekker; Morris, Andrew P.; Lindgren, Cecilia M.; Berry, Andrew; Johnson, Paul R.; Hanley, Neil; Groop, Leif C.; McCarthy, Mark I.; Gloyn, Anna L. (2013). Insights Into the Molecular Mechanism for 2 Diabetes Susceptibility at the KCNQ1 Locus From Temporal Changes in Imprinting Status in Human Islets. Diabetes, 62 (3), 987−992. DOI: 10.2337/db12-0819.
1.1.
2013
Andreassen, Ole A.; Djurovic, Srdjan; Thompson, Wesley K.; Schork, Andrew J.; Kendler, Kenneth S.; O'Donovan, Michael C.; Rujescu, Dan; Werge, Thomas; van de Bunt, Martijn; Morris, Andrew P.; McCarthy, Mark I.; Roddey, J. Cooper; McEvoy, Linda K.; Desikan, Rahul S.; Dale, Anders M. (2013). Improved Detection of Common Variants Associated with Schizophrenia by Leveraging Pleiotropy with Cardiovascular-Disease Risk Factors. The American Journal of Human Genetics, 92 (2), 197−209.10.1016/j.ajhg.2013.01.001.
1.1.
2013
Ma, R. C. W.; Hu, C.; Tam, C. H.; Zhang, R.; Kwan, P.; Leung, T. F.; Thomas, G. N.; Go, M. J.; Hara, K.; Sim, X.; Ho, J. S. K.; Wang, C.; Li, H.; Lu, L.; Wang, Y.; Li, J. W.; Wang, Y.; Lam, V. K. L.; Wang, J.; Yu, W. ... Jia, W. (2013). Genome-wide association study in a Chinese population identifies a susceptibility locus for type 2 diabetes at 7q32 near PAX4. Diabetologia, 56 (6), 1291−1305.10.1007/s00125-013-2874-4.
1.1.
2013
Albrechtsen, A.; Grarup, N.; Li, Y.; Sparso, T.; Tian, G.; Cao, H.; Jiang, T.; Kim, S. Y.; Korneliussen, T.; Li, Q.; Nie, C.; Wu, R.; Skotte, L.; Morris, A. P.; Ladenvall, C.; Cauchi, S.; Stancakova, A.; Andersen, G.; Astrup, A.; Banasik, K. ... Pedersen, O. (2013). Exome sequencing-driven discovery of coding polymorphisms associated with common metabolic phenotypes. Diabetologia, 56 (2), 298−310.10.1007/s00125-012-2756-1.
5.1.
2013
Lagou, V.; Mägi, R.; Surakka, I. ; Sarin, A. -P.; Horikoshi, M.; Thorleifsson, G. ; Hagg, S.; Beekman, M.; Ladenvall, C.; Hottenga, J. -J.; Ried, J. S.; McCarthy, M. I.Morris, A.; Ripatti, S.; Prokopenko, I. (2013). Pleiotropic effects on lipid levels and obesity identified in multi-trait meta-analysis of genome-wide association studies (GWAS) of type 2 diabetes related traits. DIABETOLOGIA, 56: 49th Annual Meeting of the European-Association-for-the-Study-of-Diabetes (EASD), Barcelona, SPAIN, SEP 23-27, 2013. Springer, S60−S60.
5.1.
2013
Horikoshi, M.; Mägi, R.; Surakka, I.; Sarin, A. -P.; Mahajan, A.; Marullo, L.; Ferreira, T. ; Esko, T.; Lindgren, C. M.; Morris, A. P.; McCarthy, M. I.; Ripatti, S.; Prokopenko, I; ENGAGE, Consortium. (2013). Large-scale genome-wide association meta-analysis of the 1000 genomes project imputed data identifies novel susceptibility loci for glycaemic and obesity traits. DIABETOLOGIA, 56: 49th Annual Meeting of the European-Association-for-the-Study-of-Diabetes (EASD), Barcelona, SPAIN, SEP 23-27, 2013. Springer, S60−S61.
1.1.
2012
Marquez, M; Huyvaert, M; Perry, JR; Pearson, RD; Falchi, M; Morris, AP; Vivequin, S; Lobbens, S; Yengo, L; Gaget, S; Pattou, F; Poulain-Godefroy, O; Charpentier, G; Carlsson, LM; Jacobson, P; Sjöström, L; Lantieri, O; Heude, B; Walley, A; Balkau, B ... Cauchi, S. (2012). Low-frequency variants in HMGA1 are not associated with type 2 diabetes risk. Diabetes, 61 (2), 524−530.10.2337/db11-0728.
1.1.
2012
Cho, YS; Chen, CH; Hu, C; Long, JR; Ong, RTH; Sim, XL; Takeuchi, F; Wu, Y; Go, MJ; Yamauchi, T; Chang, YC; Kwak, SH; Ma, RCW; Yamamoto, K; Adair, LS; Aung, T; Cai, QY; Chang, LC; Chen, YT; Gao, YT ... Seielstad, M. (2012). Meta-analysis of genome-wide association studies identifies eight new loci for type 2 diabetes in East Asians. Nature Genetics, 44 (1), 67−U97.10.1038/ng.1019.
1.1.
2012
Mägi, R; Asimit, JL; Day-Williams, AG; Zeggini, E; Morris, AP. (2012). Genome-Wide Association Analysis of Imputed Rare Variants: Application to Seven Common Complex Diseases. Genetic Epidemiology, 36 (8), 785−796.10.1002/gepi.21675.
1.1.
2012
the DIAbetes Genetics Replication And Meta-analysis (DIAGRAM), Consortium; Morris, AP; Voight, BF; Teslovich, TM; Ferreira, T; Segrè, AV; Steinthorsdottir, V; Strawbridge, RJ; Khan, H; Grallert, H; Mahajan, A; Prokopenko, I; Kang, HM; Dina, C; Esko, T; Fraser, RM; Kanoni, S; Kumar, A; Lagou, V; Langenberg, C ... McCarthy, MI. (2012). Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes. Nature Genetics, 981−990.10.1038/ng.2383.
1.1.
2012
Scott, RA.; Lagou, V.; Welch, RP.; Wheeler, E.; Montasser, ME.; Luan, J.; Mägi, R.; Strawbridge, RJ.; Rehnberg, E.; Gustafsson, S.; Kanoni, S.; Rasmussen-Torvik, LJ.; Yengo, L.; Lecoeur, C.; Shungin, D.; Sanna, S.; Sidore, C.; Johnson, PC.; Jukema, JW.; Johnson, T. ... Barroso, I. (2012). Large-scale association analyses identify new loci influencing glycemic traits and provide insight into the underlying biological pathways. Nature Genetics, 44 (9), 991−1005. DOI: 10.1038/ng.2385.
1.1.
2012
Yang, J; Ferreira, T; Morris, AP; Medland, SE; GIANT, consortium; DIAGRAM, consortium; Madden, PAF; Heath, AC; Martin, NG; Montgomery, GW; Weedon, MN; Loos, RJ; Frayling, TM; McCarthy, MI; Hirschhorn, JN; Goddard, ME; Visscher, PM. (2012). Conditional and joint multiple-SNP analysis of GWAS summary statistics identifies additional variants influencing complex traits. Nature Genetics, 44, 369−375.
1.1.
2012
Palmer, Nicholette D; McDonough, Caitrin W; Hicks, Pamela J; Roh, Bong H; Wing, Maria R; An, S Sandy; Hester, Jessica M; Cooke, Jessica N; Bostrom, Meredith A; Rudock, Megan E; Talbert, Matthew E; Lewis, Joshua P; Ferrara, Assiamira; Lu, Lingyi; Ziegler, Julie T; Sale, Michele M; Divers, Jasmin; Shriner, Daniel; Adeyemo, Adebowale; Rotimi, Charles N ... Sladek, Robert (2012). A genome-wide association search for type 2 diabetes genes in African Americans. PLOS ONE, 7 (1), e29202−e29202.
1.1.
2012
Scerri, Thomas S.; Darki, Fahimeh; Newbury, Dianne F.; Whitehouse, Andrew J. O.; Peyrard-Janvid, Myriam; Matsson, Hans; Ang, Qi W.; Pennell, Craig E.; Ring, Susan; Stein, John; Morris, Andrew P.; Monaco, Anthony P.; Kere, Juha; Talcott, Joel B.; Klingberg, Torkel; Paracchini, Silvia (2012). The Dyslexia Candidate Locus on 2p12 Is Associated with General Cognitive Ability and White Matter Structure. PLoS ONE, 7 (11), ARTN e50321.10.1371/journal.pone.0050321.
1.1.
2012
Nyholt, Dale R.; Low, Siew-Kee; Anderson, Carl A.; Painter, Jodie N.; Uno, Satoko; Morris, Andrew P.; MacGregor, Stuart; Gordon, Scott D.; Henders, Anjali K.; Martin, Nicholas G.; Attia, John; Holliday, Elizabeth G.; McEvoy, Mark; Scott, Rodney J.; Kennedy, Stephen H.; Treloar, Susan A.; Missmer, Stacey A.; Adachi, Sosuke; Tanaka, Kenichi; Nakamura, Yusuke ... Montgomery, Grant W. (2012). Genome-wide association meta-analysis identifies new endometriosis risk loci. Nature Genetics, 44 (12), 1355−1359.10.1038/ng.2445.
1.1.
2012
Ho, Jennifer E.; Mahajan, Anubha; Chen, Ming-Huei; Larson, Martin G.; McCabe, Elizabeth L.; Ghorbani, Anahita; Cheng, Susan; Johnson, Andrew D.; Lindgren, Cecilia M.; Kempf, Tibor; Lind, Lars; Ingelsson, Erik; Vasan, Ramachandran S.; Januzzi, James; Wollert, Kai C.; Morris, Andrew P.; Wang, Thomas J. (2012). Clinical and Genetic Correlates of Growth Differentiation Factor 15 in the Community. Clinical Chemistry, 58 (11), 1582−1591.10.1373/clinchem.2012.190322.
1.1.
2012
Franceschini, Nora; van Rooij, Frank J. A.; Prins, Bram P.; Feitosa, Mary F.; Karakas, Mahir; Eckfeldt, John H.; Folsom, Aaron R.; Kopp, Jeffrey; Vaez, Ahmad; Andrews, Jeanette S.; Baumert, Jens; Boraska, Vesna; Broer, Linda; Hayward, Caroline; Ngwa, Julius S.; Okada, Yukinori; Polasek, Ozren; Westra, Harm-Jan; Wang, Ying A.; Del Greco M, Fabiola ... Morris, Andrew P. (2012). Discovery and Fine Mapping of Serum Protein Loci through Transethnic Meta-analysis. The American Journal of Human Genetics, 91 (4), 744−753.10.1016/j.ajhg.2012.08.021.
1.1.
2012
Voight, Benjamin F.; Kang, Hyun Min; Ding, Jun; Palmer, Cameron D.; Sidore, Carlo; Chines, Peter S.; Burtt, Noel P.; Fuchsberger, Christian; Li, Yanming; Erdmann, Jeanette; Frayling, Timothy M.; Heid, Iris M.; Jackson, Anne U.; Johnson, Toby; Kilpelaeinen, Tuomas O.; Lindgren, Cecilia M.; Morris, Andrew P.; Prokopenko, Inga; Randall, Joshua C.; Saxena, Richa ... Boehnke, Michael (2012). The Metabochip, a Custom Genotyping Array for Genetic Studies of Metabolic, Cardiovascular, and Anthropometric Traits. PLoS Genetics, 8 (8), ARTN e1002793.10.1371/journal.pgen.1002793.
1.1.
2012
Perry, John R. B.; Voight, Benjamin F.; Yengo, Loic; Amin, Najaf; Dupuis, Josee; Ganser, Martha; Grallert, Harald; Navarro, Pau; Li, Man; Qi, Lu; Steinthorsdottir, Valgerdur; Scott, Robert A.; Almgren, Peter; Arking, Dan E.; Aulchenko, Yurii; Balkau, Beverley; Benediktsson, Rafn; Bergman, Richard N.; Boerwinkle, Eric; Bonnycastle, Lori ... Cauchi, Stephane (2012). Stratifying Type 2 Diabetes Cases by BMI Identifies Genetic Risk Variants in LAMA1 and Enrichment for Risk Variants in Lean Compared to Obese Cases. PLoS Genetics, 8 (5), ARTN e1002741.10.1371/journal.pgen.1002741.
1.1.
2012
Asimit, Jennifer L.; Day-Williams, Aaron G.; Morris, Andrew P.; Zeggini, Eleftheria (2012). ARIEL and AMELIA: Testing for an Accumulation of Rare Variants Using Next-Generation Sequencing Data. Human Heredity, 73 (2), 84−94.10.1159/000336982.
1.1.
2012
Orozco, Gisela; Ioannidis, John P. A.; Morris, Andrew; Zeggini, Eleftheria (2012). Sex-specific differences in effect size estimates at established complex trait loci. International Journal of Epidemiology, 41 (5), 1376−1382.10.1093/ije/dys104.
1.1.
2012
Dastani, Z; Hivert, M-F; Timpson, N; Perry, JRB; Yuan, X; Scott, RA; Henneman, P; Heid, IM; Kizer, JR; Lyytikäinen, L-P; et, al. (2012). Novel Loci for Adiponectin Levels and Their Influence on Type 2 Diabetes and Metabolic Traits: A Multi-Ethnic Meta-Analysis of 45,891 Individuals. PLOS Genetics, 8 (3), e1002607−e1002607.
1.1.
2012
Maller, Julian B.; McVean, Gilean; Byrnes, Jake; Vukcevic, Damjan; Palin, Kimmo; Su, Zhan; Howson, Joanna M. M.; Auton, Adam; Myers, Simon; Morris, Andrew; Pirinen, Matti; Brown, Matthew A.; Burton, Paul R.; Caulfield, Mark J.; Compston, Alastair; Farrall, Martin; Hall, Alistair S.; Hattersley, Andrew T.; Hill, Adrian V. S.; Mathew, Christopher G. ... Donnelly, Peter (2012). Bayesian refinement of association signals for 14 loci in 3 common diseases. Nature Genetics, 44 (12), 1294−1301.10.1038/ng.2435.
5.1.
2012
Mägi, R; Morris, AP. (2012). Genome-wide association analysis of rare variants identifies potential novel susceptibility genes for type 1 diabetes and coronary artery disease. ANNALS OF HUMAN GENETICS, 76: European Mathematical Genetics Meeting, Gottingen, GERMANY, APR 12-13, 2012. Wiley-Blackwell, 421−422.
5.1.
2012
Mägi, R; Horikoshi, M; Surakka, I; Wiltshire, S; Sarin, AP; Mahajan, A; Marullo, L; Ferreira, T; Hagg, S; Ried, JS; Winkler, T; Thorleifsson, G; Tsernikova, N; Esko, T; Willenborg, C; Nelson, CP; Beekman, M; Willems, SM; McCarthy, MI; Morris, AP ... Prokopenko, I. (2012). Large-scale Genome-wide Association Meta-analysis Using Imputation from 2188-haplotype 1000 Genomes Reference Panel Identifies Novel Susceptibility Loci for Anthropometric and Glycemic Traits. GENETIC EPIDEMIOLOGY, 36: Annual Meeting of the International-Genetic-Epidemiology-Society (IGES), Stevenson, WA, OCT 18-20, 2012. Wiley-Blackwell, 776−777. (7).
1.1.
2011
Morris, Andrew P. (2011). Transethnic meta-analysis of genomewide association studies. Genetic Epidemiology, 35 (8), 809−822.10.1002/gepi.20630.
1.1.
2011
Bhattacharya, K; McCarthy, MI; Morris, AP. (2011). Rapid testing of gene-gene interactions in genome-wide association studies of binary and quantitative phenotypes. Genetic Epidemiology, 35 (8), 800−808.10.1002/gepi.20629.
1.1.
2011
Chapman, K; Ferreira, T; Morris, A; Asimit, J; Zeggini, E. (2011). Defining the power limits of genome-wide association scan meta-analyses. Genetic Epidemiology, 35 (8), 781−789.10.1002/gepi.20627.
1.1.
2011
Kooner, JS; Saleheen, D; Sim, X; Sehmi, J; Zhang, WH; Frossard, P; Been, LF; Chia, KS; Dimas, AS; Hassanali, N; Jafar, T; Jowett, JBM; Li, XZ; Radha, V; Rees, SD; Takeuchi, F; Young, R; Aung, T; Basit, A; Chidambaram, M ... Chambers, JC. (2011). Genome-wide association study in individuals of South Asian ancestry identifies six new type 2 diabetes susceptibility loci. Nature Genetics, 43 (10), 984−U94.10.1038/ng.921.
1.1.
2011
Min, JL; Taylor, JM; Richards, JB; Watts, T; Pettersson, FH; Broxholme, J; Ahmadi, KR; Surdulescu, GL; Lowy, E; Gieger, C; Newton-Cheh, C; Perola, M; Soranzo, N; Surakka, I; Lindgren, CM; Ragoussis, J; Morris, AP; Cardon, LR; Spector, TD; Zondervan, KT. (2011). The use of genome-wide eQTL associations in lymphoblastoid cell lines to identify novel genetic pathways involved in complex traits. PLoS ONE, 6 (7), e22070.10.1371/journal.pone.0022070.
1.1.
2011
Clarke, GM; Anderson, CA; Pettersson, FH; Cardon, LR; Morris, AP; Zondervan, KT. (2011). Basic statistical analysis in genetic case-control studies. Nature Protocols, 6 (2), 121−133.10.1038/nprot.2010.182.
1.1.
2011
Painter, JN; Anderson, CA; Nyholt, DR; Macgregor, S; Lin, J; Lee, SH; Lambert, A; Zhao, ZZ; Roseman, F; Guo, Q; Gordon, SD; Wallace, L; Henders, AK; Visscher, PM; Kraft, P; Martin, NG; Morris, AP; Treloar, SA; Kennedy, SH; Missmer, SA ... Zondervan, KT. (2011). Genome-wide association study identifies a locus at 7p15.2 associated with endometriosis. Nature Genetics, 43 (1), 51−U69.10.1038/ng.731.
1.1.
2011
Fox, E.R.; Young, J.H.; Li, Y.; Dreisbach, A.W.; Keating, B.J.; Musani, S.K.; Liu, K.; Morrison, A.C.; Ganesh, S.; Kutlar, A.; Ramachandran, V.S.; Polak, J.F.; Fabsitz, R.R.; Dries, D.L.; Farlow, D.N.; Redline, S.; Adeyemo, A.; Hirschorn, J.N.; Sun, Y.V.; Wyatt, S.B. ... Newton-Cheh, C. (2011). Association of genetic variation with systolic and diastolic blood pressure among African Americans: the Candidate Gene Association Resource study. Human Molecular Genetics, 20 (11), 2273−2284.
1.1.
2011
Scerri, Tom S.; Morris, Andrew P.; Buckingham, Lyn-Louise; Newbury, Dianne F.; Miller, Laura L.; Monaco, Anthony P.; Bishop, Dorothy V. M.; Paracchini, Silvia (2011). DCDC2, KIAA0319 and CMIP Are Associated with Reading-Related Traits. Biological Psychiatry, 70 (3), 237−245.10.1016/j.biopsych.2011.02.005.
1.1.
2011
Scerri, Thomas S.; Brandler, William M.; Paracchini, Silvia; Morris, Andrew P.; Ring, Susan M.; Richardson, Alex J.; Talcott, Joel B.; Stein, John; Monaco, Anthony P. (2011). PCSK6 is associated with handedness in individuals with dyslexia. Human Molecular Genetics, 20 (3), 608−614.10.1093/hmg/ddq475.
1.1.
2011
Bell, Jordana T.; Timpson, Nicholas J.; Rayner, N. William; Zeggini, Eleftheria; Frayling, Timothy M.; Hattersley, Andrew T.; Morris, Andrew P.; McCarthy, Mark I. (2011). Genome-Wide Association Scan Allowing for Epistasis in Type 2 Diabetes. Annals of Human Genetics, 75 (1), 10−19.10.1111/j.1469-1809.2010.00629.x.
1.1.
2011
Jafar-Mohammadi, B.; Groves, C. J.; Gjesing, A. P.; Herrera, B. M.; Winckler, W.; Stringham, H. M.; Morris, A. P.; Lauritzen, T.; Doney, A. S. F.; Morris, A. D.; Weedon, M. N.; Swift, A. J.; Kuusisto, J.; Laakso, M.; Altshuler, D.; Hattersley, A. T.; Collins, F. S.; Boehnke, M.; Hansen, T.; Pedersen, O. ... McCarthy, M. I. (2011). A role for coding functional variants in HNF4A in type 2 diabetes susceptibility. Diabetologia, 54 (1), 111−119.10.1007/s00125-010-1916-4.
1.1.
2011
Scerri TS, Paracchini S, Morris A, MacPhie IL, Talcott J, Stein J, Smith SD, Pennington BF, Olson RK, DeFries JC, Monaco AP, Richardson AJ. (2011). Identification of candidate genes for dyslexia susceptibility on chromosome 18. PLoS ONE, 5 (10), e13712.10.1371/journal.pone.0013712.
1.2.
2011
Mägi, R.; Kumar, A.; Morris, AP. (2011). Assessing the impact of missing genotype data in rare variant association analysis. BMC Proceedings, 9 (5), S107−S107.
3.1.
2011
Morris, A.P. (2011). Haplotype methods for population-based association studies. In: “Analysis Of Complex Disease Association Studies”. In: Edited by Zeggini E, Morris AP. (Ed.). Analysis Of Complex Disease Association Studies (117−195).. Elsevier.
6.8.
2011
Voight, Benjamin F.; Scott, Laura J.; Steinthorsdottir, Valgerdur; Morris, Andrew P.; Dina, Christian; Welch, Ryan P.; Zeggini, Eleftheria; Huth, Cornelia; Aulchenko, Yurii S.; Thorleifsson, Gudmar; McCulloch, Laura J.; Ferreira, Teresa; Grallert, Harald; Amin, Najaf; Wu, Guanming; Willer, Cristen J.; Raychaudhuri, Soumya; McCarroll, Steve A.; Langenberg, Claudia; Hofmann, Oliver M. ... McCarthy, Mark I. (2011). Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis (vol 42, pg 579, 2010). Nature Genetics, 42 (4), 388−388. DOI: 10.1038/ng0411-388b.
1.1.
2010
Lawrence, R; Day-Williams, AG; Elliott, KS; Morris, AP; Zeggini, E. (2010). CCRaVAT and QuTie-enabling analysis of rare variants in large-scale case control and quantitative trait association studies. BMC Bioinformatics, 11, No 527.10.1186/1471-2105-11-527.
1.1.
2010
Bowes, J; Lawrence, R; Eyre, S; Panoutsopoulou, K; Orozco, G; Elliott, KS; Ke, X; Morris, AP; UKRAG, Thomson, W; Worthington, J; Barton, A; Zeggini, E. (2010). Rare variation at the TNFAIP3 locus and susceptibility to rheumatoid arthritis. Human Genetics, 128 (6), 627−633.10.1007/s00439-010-0889-1.
1.1.
2010
Thye, T; Vannberg, FO; Wong, SH; Owusu-Dabo, E; Osei, I; Gyapong, J; Sirugo, G; Sisay-Joof, F; Enimil, A; Chinbuah, MA; Floyd, S; Warndorff, DK; Sichali, L; Malema, S; Crampin, AC; Ngwira, B; Teo, YY; Small, K; Rockett, K; Kwiatkowski, D ... Hill, AV. (2010). Genome-wide association analyses identifies a susceptibility locus for tuberculosis on chromosome 18q11.2. Nature Genetics, 42 (9), 739−741.10.1038/ng.639.
1.1.
2010
Craddock, N.; Hurles, ME.; Cardin, N.; Pearson, RD.; Plagnol, V.; Robson, S.; Vukcevic, D.; Barnes, C.; Conrad, DF.; Giannoulatou, E.; Holmes, C.; Marchini, JL.; Stirrups, K.; Tobin, MD.; Wain, LV.; Yau, C.; Aerts, J.; Ahmad, T.; Andrews, TD.; Arbury, H. ... Donnelly, P (2010). Genome-wide association study of CNVs in 16,000 cases of eight common diseases and 3,000 shared controls. Nature, 464 (7289), 713−720.10.1038/nature08979.
1.1.
2010
Zhuang, JJ; Zondervan, K; Nyberg, F; Harbron, C; Jawaid, A; Cardon, LR; Barratt, BJ; Morris, AP. (2010). Optimizing the power of genome-wide association studies by using publicly available reference samples to expand the control group. Genetic Epidemiology, 34 (4), 319−326.10.1002/gepi.20482.
1.1.
2010
Clarke, GM; Morris, AP. (2010). A comparison of sample size and power in case-only association studies of gene-environment interaction. American Journal of Epidemiology, 171 (4), 498−505.10.1093/aje/kwp398.
1.1.
2010
Morris, AP; Lindgren, CM; Zeggini, E; Timpson, NJ; Frayling, TM; Hattersley, AT; McCarthy, MI. (2010). A powerful approach to sub-phenotype analysis in population-based genetic association studies. Genetic Epidemiology, 34 (4), 335−343.10.1002/gepi.20486.
1.1.
2010
Fawcett, KA; Wheeler, E; Morris, AP; Ricketts, SL; Hallmans, G; Rolandsson, O; Daly, A; Wasson, J; Permutt, A; Hattersley, AT; Glaser, B; Franks, PW; McCarthy, MI; Wareham, NJ; Sandhu, MS; Barroso, I. (2010). Detailed investigation of the role of common and low-frequency WFS1 variants in type 2 diabetes risk. Diabetes, 59 (3), 741−746.10.2337/db09-0920.
1.1.
2010
Morris, AP; Zeggini, E. (2010). An evaluation of statistical approaches to rare variant analysis in genetic association studies. Genetic Epidemiology, 34 (2), 188−193.10.1002/gepi.20450.
1.1.
2010
Mägi, Reedik; Lindgren, Cecilia M.; Morris, Andrew P. (2010). Meta-analysis of sex-specific genome-wide association studies. Genetic Epidemiology, 34 (8), 846−853.10.1002/gepi.20540.
1.1.
2010
Lango Allen, Hana; Estrada, Karol; Lettre, Guillaume; Berndt, Sonja I; Weedon, Michael N; Rivadeneira, Fernando; Willer, Cristen J; Jackson, Anne U; Vedantam, Sailaja; Raychaudhuri, Soumya; Ferreira, Teresa; Wood, Andrew R; Weyant, Robert J; Segre, Ayellet V; Speliotes, Elizabeth K; Wheeler, Eleanor; Soranzo, Nicole; Park, Ju-Hyun; Yang, Jian; Gudbjartsson, Daniel ... Hirschhorn, Joel N (2010). Hundreds of variants clustered in genomic loci and biological pathways affect human height. Nature, 467 (7317), 832−838.
1.1.
2010
Dupuis, J.; Langenberg, C.; Prokopenko, I.; Saxena, R.; Soranzo, N.; Jackson, A.U.; Wheeler, E.; Glazer, N.L.; Bouatia-Naji, N.; Gloyn, A.L.; Lindgren, C.M.; Mägi, R.; Morris, A.P.; Randall, J.; Johnson, T.; Elliott, P.; Rybin, D.; Thorleifsson, G.; Steinthorsdottir, V.; Henneman, P. ... Mitchell, B.D (2010). New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk. Nature Genetics, 42 (2), 105−116.10.1038/ng.520.
1.1.
2010
Mägi, R; Morris, AP. (2010). GWAMA: software for genome-wide association meta-analysis. BMC Bioinformatics, 11 (288), 288.10.1186/1471-2105-11-288.
1.1.
2010
Anderson, Carl A.; Pettersson, Fredrik H.; Clarke, Geraldine M.; Cardon, Lon R.; Morris, Andrew P.; Zondervan, Krina T. (2010). Data quality control in genetic case-control association studies. Nature Protocols, 5 (9), 1564−1573.10.1038/nprot.2010.116.
1.1.
2010
Speliotes, E.K.; Willer, C.J.; Berndt, S.I.; Monda, K.L.; Thorleifsson, G.; Jackson, A.U.; Allen, H.L.; Lindgren, C.M.; Luan, J.; Mägi, R.; Randall, J.C.; Vedantam, S.; Winkler, T.W.; Workalemahu, T.; Heid, I.M.; Qi, L.; Steinthorsdottir, V.; Weedon, M.N.; Wheeler, E.; Wood, A.R. ... Hayward, C. (2010). Genome-wide association study of 249,796 individuals reveals eighteen loci associated with body mass index. Nature Genetics, 11, 937−948. DOI: 10.1038/ng.686.
1.1.
2010
Heid, Iris M; Jackson, Anne U; Randall, Joshua C; Winkler, Thomas W; Qi, Lu; Steinthorsdottir, Valgerdur; Thorleifsson, Gudmar; Zillikens, M Carola; Speliotes, Elizabeth K; Mägi, Reedik; Workalemahu, Tsegaselassie; White, Charles C; Bouatia-Naji, Nabila; Harris, Tamara B; Berndt, Sonja I; Ingelsson, Erik; Willer, Cristen J; Weedon, Michael N; Luan, Jian'an; Vedantam, Sailaja ... Lindgren, Cecilia M (2010). Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution. Nature Genetics, 42 (11), 949−960. DOI: 10.1038/ng.685.
1.1.
2010
Cho EY, Jang Y, Shin ES, Jang HY, Yoo Y-K, Kim S, Jang JH, Lee JY, Yun MH, Park MY, Chae JS, Lim JW, Shin DJ, Park S, Lee JH, Han BG, Rae KH, Cardon LR, Morris AP, Lee JE, Clarke GM. (2010). Genome-wide association analysis and replication of coronary artery disease in South Korea suggests a causal variant common to diverse populations. Heart Asia, 2 (1), 104−108. DOI: 10.1136/ha.2009.001370.
1.1.
2010
Tönjes A, Zeggini E, Kovacs P, Böttcher Y, Schleinitz D, Dietrich K, Morris AP, Enigk B, Rayner NW, Koriath M, Eszlinger M, Kemppinen A, Prokopenko I, Hoffmann K, Teupser D, Thiery J, Krohn K, McCarthy MI, Stumvoll M. (2010). Association of FTO variants with BMI and fat mass in the self-contained population of Sorbs in Germany. European Journal of Human Genetics, 18 (1), 104−110. DOI: 10.1038/ejhg.2009.107.
5.1.
2010
Mägi, R; Morris, AP. (2010). GRANVIL: Rare Variant Analysis of Genome-Wide Association Studies. Genetic Epidemiology, 34: 19th Annual Meeting of the International-Genetic-Epidemiology-Society, Boston, MA, OCT 10-12, 2010. Wiley-Blackwell, 926−926. (8).
1.1.
2009
Lindgren, CM; Heid, IM; Randall, JC; Steinthorsdottir, V; Qi, L; Speliotes, EK; Thorleifsson, G; Willer, CJ; Herrera, BM; Jackson, AU; Lim, N; Scheet, P; Soranzo, N; Amin, N; Aulchenko, YS; Chambers, JC; Drong, A; Luan, JA; Lyon, HN; Rivadeneira, F ... McCarthy, M (2009). Genome-wide association scan meta-analysis identifies three loci influencing adiposity and fat distribution. PLoS Genetics, 5 (6), No e1000508. DOI: 10.1371/journal.pgen.1000508.
1.1.
2009
Jallow, M; Teo, YY; Small, K; Rockett, KA; Deloukas, P; Clark, TG; Kivinen, K; Bojang, KA; Conway, DJ; Pinder, M; Sirugo, G; Sisay-Joof, F; Usen, S; Auburn, S; Bumpstead, SJ; Campino, S; Coffey, A; Dunham, A; Fry, AE; Green, A ... Kwiatkowski, DP (2009). Genome-wide and fine-resolution association analysis of malaria in West Africa. Nature Genetics, 41 (6), 657−665. DOI: 10.1038/ng.388.
1.1.
2009
Maestrini, E; Pagnamenta, AT; Lamb, JA; Bacchelli, E; Sykes, NH; Sousa, I; Toma, C; Barnby, G; Butler, H; Winchester, L; Scerri, TS; Minopoli, F; Reichert, J; Cai, G; Buxbaum, JD; Korvatska, O; Schellenberg, GD; Dawson, G; Bildt, AD; Minderaa, RB ... Monaco, AP. (2009). High-density SNP association study and copy number variation analysis of the AUTS1 and AUTS5 loci implicate the IMMP2L-DOCK4 gene region in autism susceptibility. Molecular Psychiatry, 15 (9), 954−968. DOI: 10.1038/mp.2009.34.
1.1.
2009
Pettersson, FH; Anderson, CA; Clarke, GM; Barrett, JC; Cardon, LR; Morris, AP; Zondervan, KT. (2009). Marker selection for genetic case-control association studies. Nature Protocols, 4 (5), 743−752. DOI: 10.1038/nprot.2009.38.
1.1.
2009
Cooney, R; Cummings, JR; Pathan, S; Beckly, J; Geremia, A; Hancock, L; Guo, C; Morris, A; Jewell, DP. (2009). Association between genetic variants in myosin IXB and Crohn’s disease. Inflammatory Bowel Diseases, 15 (7), 1014−1021. DOI: 10.1002/ibd.20885.
1.1.
2009
Diakite, M; Clark, TG; Auburn, S; Campino, S; Fry, AE; Green, A; Morris, AP; Richardson, A; Jallow, M; Sisay-Joof, F; Pinder, M; Kwiatkowski, DP; Rockett, KA. (2009). A genetic association study in the Gambia using tagging polymorphisms in the major histocompatibility complex class III region implicates a HLA-B associated transcript 2 polymorphism in severe malaria susceptibility. Human Genetics, 125 (1), 105−109. DOI: 10.1007/s00439-008-0597-2.
1.1.
2009
Carpenter, D; Morris, A; Robinson, RL; Booms, P; Iles, D; Halsall, PJ; Steele, D; Hopkins, PM; Shaw, MA. (2009). Analysis of RYR1 haplotype profile in patients with malignant hyperthermia. Annals of Human Genetics, 73, 10−18. DOI: 10.1111/j.1469-1809.2008.00482.x.
1.1.
2009
Zhuang JJ, Morris AP. (2009). Assessment of sex-specific effects in a genome-wide association study of rheumatoid arthritis. BMC Proceedings, 3 (S90), 1−4. DOI: 10.1186/1753-6561-3-S7-S90.
1.1.
2009
Clarke, Geraldine M; Pettersson, Fredrik H; Morris, Andrew P (2009). A comparison of case-only designs for detecting gene × gene interaction in rheumatoid arthritis using genome-wide case-control data in Genetic Analysis Workshop 16. BMC Proceedings, 3 (S7), 1−4. DOI: 10.1186/1753-6561-3-S7-S73.
1.1.
2009
Morris, Andrew P; Zeggini, Eleftheria; Lindgren, Cecilia M (2009). Identification of novel putative rheumatoid arthritis susceptibility genes via analysis of rare variants. BMC Proceedings, 3 (S7), 1−5. DOI: 10.1186/1753-6561-3-S7-S131.
1.1.
2009
Carpenter, Danielle; Ringrose, Christopher; Leo, Vincenzo; Morris, Andrew; Robinson, Rachel L.; Halsall, P. Jane; Hopkins, Philip M.; Shaw, Marie-Anne (2009). The role of CACNA1S in predisposition to malignant hyperthermia. BMC Medical Genetics, 10, ARTN 104. DOI: 10.1186/1471-2350-10-104.
1.1.
2009
Pathan, S.; Gowdy, R. E.; Cooney, R.; Beckly, J. B.; Hancock, L.; Guo, C.; Barrett, J. C.; Morris, A.; Jewell, D. P. (2009). Confirmation of the novel association at the BTNL2 locus with ulcerative colitis. Tissue Antigens, 74 (4), 322−329. DOI: 10.1111/j.1399-0039.2009.01314.x.
1.1.
2008
Paracchini, Silvia; Steer, Colin D.; Buckingham, Lyn-Louise; Morris, Andrew P.; Ring, Susan; Scerri, Thomas; Stein, John; Pembrey, Marcus E.; Ragoussis, Jiannis; Golding, Jean; Monaco, Anthony P. (2008). Association of the KIAA0319 Dyslexia Susceptibility Gene With Reading Skills in the General Population. American Journal of Psychiatry, 165 (12), 1576−1584. DOI: 10.1176/appi.ajp.2008.07121872.
1.1.
2008
Orton, SM; Morris, AP; Herrera, BM; Ramagopalan, SV; Lincoln, MR; Chao, MJ; Vieth, R; Sadovnick, AD; Ebers, GC. (2008). Evidence for genetic regulation of vitamin D status in twins with multiple sclerosis. The American Journal of Clinical Nutrition, 88 (2), 441−447.
1.1.
2008
Anderson, CA; Pettersson, FH; Barrett, JC; Zhuang, JJ; Ragoussis, J; Cardon, LR; Morris, AP. (2008). Evaluating the effects of imputation on the power, coverage and cost efficiency of genome-wide SNP platforms. The American Journal of Human Genetics, 83 (1), 112−119. DOI: 10.1016/j.ajhg.2008.06.008.
1.1.
2008
Pettersson, F; Morris, AP; Barnes, MR; Cardon, LR. (2008). Goldsurfer2 (Gs2): a comprehensive tool for the analysis and visualisation of genome-wide association studies. BMC Bioinformatics, 9, No 138. DOI: 10.1186/1471-2105-9-138.
1.1.
2008
Beckly, John B.; Hancock, Laura; Geremia, Alessandro; Cummings, J. R. Fraser; Morris, Andrew; Cooney, Rachel; Pathan, Saad; Guo, Changcun; Jewell, Derek P. (2008). Two-stage candidate gene study of chromosome 3p demonstrates an association between nonsynonymous variants in the MST1R gene and Crohn's disease. Inflammatory Bowel Diseases, 14 (4), 500−507. DOI: 10.1002/ibd.20365.
1.1.
2008
Wiltshire, Steven; Morris, Andrew P.; Zeggini, Eleftheria (2008). Examining the statistical properties of fine-scale mapping in large-scale association studies. Genetic Epidemiology, 32 (3), 204−214. DOI: 10.1002/gepi.20295.
1.1.
2007
Newport, M; Sirugo, G; Lyons, E; Vannberg, F; Hill, AVS; Bradbury, LA; Farrar, C; Pointon, JJ; Wordsworth, P; Brown, MA; Franklyn, JA; Heward, JM; Simmonds, MJ; Gough, SC; Seal, S; Stratton, MR; Rahman, N; Ban, M; Goris, A; Sawcer, SJ ... Brown, MA (2007). Association scan of 14,500 nonsynonymous SNPs in four diseases identifies autoimmunity variants. Nature Genetics, 39 (11), 1329−1337. DOI: 10.1038/ng.2007.17.
1.1.
2007
Frazer, KA; Ballinger, DG; Cox, DR; Hinds, DA; Stuve, LL; Gibbs, RA; Belmont, JW; Boudreau, A; Hardenbol, P; Leal, SM; Pasternak, S; Wheeler, DA; Willis, TD; Yu, FL; Yang, HM; Zeng, CQ; Gao, Y; Hu, HR; Hu, WT; Li, CH ... Skol, A (2007). A second generation human haplotype map of over 3.1 million SNPs. Nature, 449 (7164), 851−U3. DOI: 10.1038/nature06258.
1.1.
2007
Clarke, GM; Carter, KW; Palmer, LJ; Morris, AP; Cardon, LR. (2007). Fine mapping versus replication in whole-genome association studies. American Journal of Human Genetics, 81 (5), 995−1005.
1.1.
2007
Dunstan, S.J.; Nguyen, T.H.; Rockett, K.; Forton, J.; Morris, A.P.; Diakite, M.; Mai, N.L.; Le, T.P.; House, D.; Parry, C.M.; Ha, V.; Nguyen, T.H.; Dougan, G.; Tran, T.H.; Kwiatowski, D.; Farrar, J.J. (2007). A TNF region haplotype offers protection from typhoid fever in Vietnamese patients. Human Genetics, 122 (1), 51−61. DOI: 10.1007/s00439-007-0372-9.
1.1.
2007
Burton, PR; Clayton, DG; Cardon, LR; Craddock, N; Deloukas, P; Duncanson, A; Kwiatkowski, DP; McCarthy, MI; Ouwehand, WH; Samani, NJ; Todd, JA; Donnelly, P; Barrett, JC; Davison, D; Easton, D; Evans, D; Leung, HT; Marchini, JL; Morris, AP; Spencer, CCA ... Worthington, J (2007). Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls. Nature, 447 (7145), 661−678. DOI: 10.1038/nature05911.
1.1.
2007
Zeggini, E.; Weedon, M.N.; Lindgren, C.M.; Frayling, T.M.; Elliott, K.S.; Lango, H.; Timpson, N.J.; Perry, J.R.; Rayner, N.W.; Freathy, R.M.; Barrett, J.C.; Shields, B.; Morris, A.P.; Ellard, S.; Groves, C.J.; Harries, L.W.; Marchini, J.L.; Owen, K.R.; Knight, B.; Cardon, L.R. ... Hattersley, A.T. (2007). Replication of genome-wide association signals in UK samples reveals risk loci for type 2 diabetes. Science, 316 (5829), 1336−1341. DOI: 10.1126/science.1142364.
1.1.
2007
Sabeti, Pardis C.; Varilly, Patrick; Fry, Ben; Lohmueller, Jason; Hostetter, Elizabeth; Cotsapas, Chris; Xie, Xiaohui; Byrne, Elizabeth H.; McCarroll, Steven A.; Gaudet, Rachelle; Schaffner, Stephen F.; Lander, Eric S. et al. (2007). Genome-wide detection and characterization of positive selection in human populations. Nature, 449 (7164), 913−920. DOI: 10.1038/nature06250.
1.1.
2007
Ramagopalan, Sreeram V.; Morris, Andrew P.; Dyment, David A.; Herrera, Blanca M.; DeLuca, Gabriele C.; Lincoln, Matthew R.; Orton, Sarah M.; Chao, Michael J.; Sadovnick, A. Dessa; Ebers, George C. (2007). The inheritance of resistance alleles in multiple sclerosis. PLoS Genetics, 3 (9), ARTN e150−1613. DOI: 10.1371/journal.pgen.0030150.
3.1.
2007
Morris, A.P. (2007). Coalescent methods for fine-scale disease-gene mapping. In: Linkage Disequilibrium and Association Mapping (123−140). . Springer. (Methods in Molecular Biology). DOI: 10.1007/978-1-59745-389-9_9.
3.1.
2007
Morris, A.P. (2007). Haplotype estimation. In: “Statistical Genetics: Gene Mapping Through Linkage And Association”. In: Edited by Neale B, Ferreira MAR, Medland SE (Ed.). Statistical Genetics: Gene Mapping Through Linkage And Association (395−418).. Taylor & Francis.
1.1.
2006
Evans, David M.; Marchini, Jonathan; Morris, Andrew P.; Cardon, Lon R. (2006). Two-stage two-locus models in genome-wide association. PLoS Genetics, 2 (9), ARTN e157−1432. DOI: 10.1371/journal.pgen.0020157.
1.1.
2006
Morris, Andrew P. (2006). A flexible Bayesian framework for modeling haplotype association with disease, allowing for dominance effects of the underlying causative variants. The American Journal of Human Genetics, 79 (4), 679−694. DOI: 10.1086/508264.
1.1.
2006
Evans, D. M.; Morris, A. P.; Cardon, L. R.; Sham, P. C. (2006). A note on the power to detect transmission distortion in parent-child trios via the transmission disequilibrium test. Behavior Genetics, 36 (6), 947−950. DOI: 10.1007/s10519-006-9087-2.
1.1.
2005
Durrant, C; Morris, AP (2005). Linkage disequilibrium mapping via cladistic analysis of phase-unknown genotypes and inferred haplotypes in the Genetic Analysis Workshop 14 simulated data. BMC Genetics, 6, ARTN S100. DOI: 10.1186/1471-2156-6-S1-S100.
1.1.
2005
Farrall, M; Morris, AP (2005). Gearing up for genome-wide gene-association studies. Human Molecular Genetics, 14, R157−R162. DOI: 10.1093/hmg/ddi273.
1.1.
2005
Zeggini, E; Rayner, W; Morris, AP; Hattersley, AT; Walker, M; Hitman, GA; Deloukas, P; Cardon, LR; McCarthy, MI (2005). An evaluation of HapMap sample size and tagging SNP performance in large-scale empirical and simulated data sets. Nature Genetics, 37 (12), 1320−1322. DOI: 10.1038/ng1670.
1.1.
2005
Lawrence, R; Evans, DM; Morris, AP; Ke, XY; Hunt, S; Paolucci, M; Ragoussis, J; Deloukas, P; Bentley, D; Cardon, LR (2005). Genetically indistinguishable SNPs and their influence on inferring the location of disease-associated variants. Genome Research, 15 (11), 1503−1510. DOI: 10.1101/gr.4217605.
1.1.
2005
Altshuler, D; Brooks, LD; Chakravarti, A; Collins, FS; Daly, MJ; Donnelly, P; Gibbs, RA; Belmont, JW; Boudreau, A; Leal, SM; Hardenbol, P; Pasternak, S; Wheeler, DA; Willis, TD; Yu, FL; Yang, HM; Zeng, CQ; Gao, Y; Hu, HR; Hu, WT ... Stewart, J (2005). A haplotype map of the human genome. Nature, 437 (7063), 1299−1320. DOI: 10.1038/nature04226.
1.1.
2005
Morris, AP (2005). Direct analysis of unphased SNP genotype data in population-based association studies via Bayesian partition modelling of haplotypes. Genetic Epidemiology, 29 (2), 91−107. DOI: 10.1002/gepi.20080.
1.1.
2005
Barnby, G; Abbott, A; Sykes, N; Morris, A; Weeks, DE; Mott, R; Lamb, J; Bailey, AJ; Monaco, AP (2005). Candidate-gene screening and association analysis at the autism-susceptibility locus on chromosome 16p: Evidence of association at GRIN2A and ABAT. The American Journal of Human Genetics, 76 (6), 950−966. DOI: 10.1086/430454.
1.1.
2005
Wiltshire, S; Morris, AP; McCarthy, MI; Cardon, LR (2005). How useful is the fine-scale mapping of complex trait linkage peaks? Evaluating the impact of additional microsatellite genotyping on the posterior probability of linkage. Genetic Epidemiology, 28 (1), 1−10. DOI: 10.1002/gepi.20023.
1.1.
2004
Evans, DM; Cardon, LR; Morris, AP (2004). Genotype prediction using a dense map of SNPs. Genetic Epidemiology, 27 (4), 375−384. DOI: 10.1002/gepi.20045.
1.1.
2004
Yalcin, B; Willis-Owen, SAG; Fullerton, J; Meesaq, A; Deacon, RM; Rawlins, JNP; Copley, RR; Morris, AP; Flint, J; Mott, R (2004). Genetic dissection of a behavioral quantitative trait locus shows that Rgs2 modulates anxiety in mice. Nature Genetics, 36 (11), 1197−1202. DOI: 10.1038/ng1450.
1.1.
2004
Ke, XY; Hunt, S; Tapper, W; Lawrence, R; Stavrides, G; Ghori, J; Whittaker, P; Collins, A; Morris, AP; Bentley, D; Cardon, LR; Deloukas, P (2004). The impact of SNP density on fine-scale patterns of linkage disequilibrium. Human Molecular Genetics, 13 (6), 577−588. DOI: 10.1093/hmg/ddh060.
1.1.
2004
Ke, XY; Durrant, C; Morris, AP; Hunt, S; Bentley, DR; Deloukas, P; Cardon, LR (2004). Efficiency and consistency of haplotype tagging of dense SNP maps in multiple samples. Human Molecular Genetics, 13 (21), 2557−2565. DOI: 10.1093/hmg/ddh294.
1.1.
2004
Foster, MW (2004). Integrating ethics and science in the international HapMap project. Nature Reviews Genetics, 5 (6), 467−475. DOI: 10.1038/nrg1351.
1.1.
2004
Durrant, C; Zondervan, KT; Cardon, LR; Hunt, S; Deloukas, P; Morris, AP (2004). Linkage disequilibrium mapping via cladistic analysis of single-nucleotide polymorphism haplotypes. The American Journal of Human Genetics, 75 (1), 35−43. DOI: 10.1086/422174.
1.1.
2004
Morris, AP; Whittaker, JC; Balding, DJ (2004). Little loss of information due to unknown phase for fine-scale linkage-disequilibrium mapping with single-nucleotide-polymorphism genotype data. The American Journal of Human Genetics, 74 (5), 945−953. DOI: 10.1086/420773.
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2003
Gibbs, RA; Belmont, JW; Hardenbol, P; Willis, TD; Yu, FL; Yang, HM; Ch'ang, LY; Huang, W; Liu, B; Shen, Y; Tam, PKH; Tsui, LC; Waye, MMY; Wong, JTF; Zeng, CQ; Zhang, QR; Chee, MS; Galver, LM; Kruglyak, S; Murray, SS ... Tanaka, T (2003). The International HapMap Project. Nature, 426 (6968), 789−796. DOI: 10.1038/nature02168.
1.1.
2003
Anagnostopoulos, T; Morris, AP; Ayres, KL; Giannelli, F; Green, PM (2003). DNA variation in a 13-Mb region including the F9gene: inferring the genealogical history and causal role of a hemophilia B mutation (IVS 5+13 A -> G). Journal of Thrombosis and Haemostasis, 1 (12), 2609−2614. DOI: 10.1111/j.1538-7836.2003.00514.x.
1.1.
2003
Morris, AP; Whittaker, JC; Xu, CF; Hosking, LK; Balding, DJ (2003). Multipoint linkage-disequilibrium mapping narrows location interval and identifies mutation heterogeneity. Proceedings of the National Academy of Sciences, 100 (23), 13442−13446. DOI: 10.1073/pnas.2235031100.
1.1.
2003
Morris, A; Pedder, A; Ayres, K (2003). Linkage disequilibrium assessment via log-linear modeling of SNP haplotype frequencies. Genetic Epidemiology, 25 (2), 106−114. DOI: 10.1002/gepi.10254.
1.1.
2003
Phillips, MS; Lawrence, R; Sachidanandam, R; Morris, AP; Balding, DJ; Donaldson, MA; Studebaker, JF; Ankener, WM; Alfisi, SV; Kuo, FS; Camisa, AL; Pazorov, V; Scott, KE; Carey, BJ; Faith, J; Katari, G; Bhatti, HA; Cyr, JM; Derohannessian, V; Elosua, C ... Cardon, LR (2003). Chromosome-wide distribution of haplotype blocks and the role of recombination hot spots. Nature Genetics, 33 (3), 382−387. DOI: 10.1038/ng1100.
1.1.
2002
Morris, AP; Whittaker, JC; Balding, DJ (2002). Fine-scale mapping of disease loci via shattered coalescent modeling of genealogies. The American Journal of Human Genetics, 70 (3), 686−707. DOI: 10.1086/339271.
1.1.
2000
Morris, AP; Whittaker, JC; Balding, DJ (2000). Bayesian fine-scale mapping of disease loci, by hidden Markov models. The American Journal of Human Genetics, 67 (1), 155−169. DOI: 10.1086/302956.
1.1.
2000
Morris, AP; Whittaker, JC (2000). Fine scale association mapping of disease loci using simplex families. Annals of Human Genetics, 64, 223−237. DOI: 10.1046/j.1469-1809.2000.6430223.x.
1.1.
2000
Whittaker, JC; Denham, MC; Morris, AP (2000). The problems of using the transmission/disequilibrium test to infer tight linkage. The American Journal of Human Genetics, 67 (2), 523−526. DOI: 10.1086/303007.
1.1.
1999
Morris AP, Whittaker JC. (1999). Generalisation of the extended transmission disequilibrium test to two unlinked disease loci. Genetic Epidemiology, 17 (S661), S661−S666.
1.1.
1998
Whittaker, J.C.; Morris, A.P.; Curnow, R.N. (1998). Using information from both parents when testing for association between marker and disease loci. Genetic Epidemiology, 15 (2), 193−200. DOI: 10.1002/(SICI)1098-2272(1998)15:2<193::AID-GEPI7>3.0.CO;2-7.
1.1.
1998
Curnow, RN; Morris, AP (1998). Pooling DNA in the identification of parents. Heredity, 80, 101−109. DOI: 10.1038/sj.hdy.6882420.
1.1.
1997
Morris AP, Curnow RN, Whittaker JC. (1997). Randomisation tests of disease-marker associations. Annals of Human Genetics, 61, 49−60. DOI: 10.1046/j.1469-1809.1997.6110047.x.
1.1.
1997
Morris, AP; Whittaker, JC; Curnow, RN (1997). A likelihood ratio test for detecting patterns of disease-marker association. Annals of Human Genetics, 61, 335−350. DOI: 10.1046/j.1469-1809.1997.6140335.x.
1.1.
1995
MORRIS, A; MORTON, NE; COLLINS, A; LAWRENCE, S; MACPHERSON, JN (1995). EVOLUTIONARY DYNAMICS OF THE FMR1 LOCUS. Annals of Human Genetics, 59, 283−289. DOI: 10.1111/j.1469-1809.1995.tb00748.x.
1.1.
1995
MORRIS, A; MORTON, NE; COLLINS, A; MACPHERSON, J; NELSON, D; SHERMAN, S (1995). AN N-ALLELE MODEL FOR PROGRESSIVE AMPLIFICATION IN THE FMR1 LOCUS. Proceedings of the National Academy of Sciences, 92 (11), 4833−4837. DOI: 10.1073/pnas.92.11.4833.
13.03.2020

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