Artur Noole

https://www.etis.ee/CV/Artur_Noole/est
25.04.1985
artur.noole@ttu.ee

Teenistuskäik

Töökohad ja ametid
01.09.2010–31.01.2014   
Tallinna Tehnikaülikool, Matemaatika-loodusteaduskond, Keemiainstituut, Orgaanilise keemia õppetool, Teadur (0,25)
15.09.2008–31.08.2010   
Tallinna Tehnikaülikool, Matemaatika-loodusteaduskond, Keemiainstituut, Orgaanilise keemia õppetool, tehnik (0,50)
01.01.2008–31.12.2008   
AS Cambrex Tallinn; laborant
01.01.2007–31.12.2007   
AS Cambrex Tallinn; laborant
 
 
Haridustee
2010–2014   
Tallinna Tehnikaülikool, filosoofiadoktori (keemia) kraad
2007–2010   
Tallinna Tehnikaülikool, loodusteaduste magistrikraad (cum laude)
2004–2007   
Tallinna Tehinkaülikool, loodusteaduste bakalaureuse kraad (cum laude)
2001–2004   
Saku Gümnaasium, keskharidus

Kvalifikatsioon

Teaduskraadid
Artur Noole, doktorikraad, 2014, (juh) Tõnis Kanger, Asymmetric Organocatalytic Synthesis of 3,3’- Disubstituted Oxindoles (Asümmeetriline organokatalüütiline 3,3’-diasendatud oksindoolide süntees), Tallinna Tehnikaülikool, Matemaatika-loodusteaduskond, Keemiainstituut, Orgaanilise keemia õppetool.
Artur Noole, magistrikraad, 2010, (juh) Tõnis Kanger, Vask (II) katalüütiline asümmeetriline Henry reaktsioon, Tallinna Tehnikaülikool, Matemaatika-loodusteaduskond, Keemiainstituut.
 
 
Teaduspreemiad ja tunnustused
2011, Artur Noole, Bruker Baltics stipendium
2011, Artur Noole, Parim teadusartikkel täppisteadustes TTÜ-s
 
 
Teadustöö põhisuunad
VALDKOND: 4. Loodusteadused ja tehnika; 4.11. Keemia ja keemiatehnika; PÕHISUUND: Orgaaniline süntees

Jooksvad projektid

Juhendatud väitekirjad

Publikatsioonid

Klass
Aasta
Publikatsioon
 
1.1.
2014
Preegel, G.; Noole, A.; Ilmarinen, K.; Järving, I.; Kanger, T.; Pehk, T.; Lopp, M. (2014). Enantioselective Organocatalytic Michael Addition of Cyclopentane-1,2-diones to Nitroolefins. Synthesis, 46 (19), 2595−2600.10.1055/s-0034-1378374.
1.1.
2014
Ošeka, M.; Noole, A.; Žari, S.; Öeren, M.; Lopp, M.; Kanger, T. (2014). Asymmetric Diastereoselective Synthesis of Spirocyclopropane Derivatives of Oxindole. European Journal of Organic Chemistry, 2014 (17), 3599−3606.
1.1.
2013
Noole, A.; Malkov, A. V.; Kanger, T.. (2013). Asymmetric Organocatalytic Synthesis of Spiro-cyclopropaneoxindoles. Synthesis, 45 (18), 2520−2524.
1.1.
2013
Noole, A.; Ilmarinen, K.; Järving, I.; Lopp, M.; Kanger, T. (2013). Asymmetric Synthesis of Congested Spiro-cyclopentaneoxindoles via an Organocatalytic Cascade Reaction. Journal of Organic Chemistry, 78 (16), 8117−8122.10.1021/jo4008223.
1.1.
2013
Noole, Artur; Ošeka, Maksim; Pehk, Tõnis; Öeren, Mario; Järving, Ivar; Elsegood, Mark; Malkov, Andrei; Lopp, Margus; Kanger, Tõnis. (2013). 3-Chlorooxindoles: Versatile Starting Materials for Asymmetric Organocatalytic Synthesis of Spirooxindoles. Advanced Synthesis and Catalysis, 355 (5), 829−835.
1.1.
2012
Noole, A.; Suckman, N.; Kabeshov, M.; Kanger, T.; Macaev, F.; Malkov, A. (2012). Highly Enantio- and Diastereoselective Generation of Two Quaternary Centers in Spirocyclopropanation of Oxindole Derivatives. Chemistry - A European Journal, 18 (47), 14929−14933.10.1002/chem.201203099.
1.1.
2012
Noole, A.; Järving, I.; Werner, F.; Lopp, M.; Malkov, A.; Kanger, T. (2012).

Organocatalytic Asymmetric Synthesis of 3-Chlorooxindoles Bearing Adjacent Quaternary–Tertiary Centers

. Organic Letters, 14 (18), 4922−4925.10.1021/ol302245b.
1.1.
2012
Noole, A.; Pehk, T.; Järving, I.; Lopp, M.; Kanger, T. (2012). Organocatalytic asymmetric synthesis of trisubstituted pyrrolidines via a cascade reaction. Tetrahedron-Asymmetry, 23 (2), 188−198.10.1016/j.tetasy.2012.01.021.
1.1.
2011
Noole, A.; Borissova, M.; Lopp, M.; Kanger, T. (2011). Enantioselective Organocatalytic Aza-Ene-Type Domino Reaction Leading to 1,4-Dihydropyridines. Journal of Organic Chemistry, 76 (6), 1538−1545.10.1021/jo200095e.
1.1.
2010
Noole, A.; Lippur, K.; Metsala, A.; Lopp, M.; Kanger, T.. (2010). Enantioselective Henry Reaction Catalyzed by CuII Salt and Bipiperidine. Journal of Organic Chemistry, 75 (4), 1313−1316.10.1021/jo902664v.
5.2.
2009
Noole, A.; Kanger, T. (2009). Synthesis of 2-(2'-piperidinyl)pyridine derivatives and their use as ligands in asymmetric Henry and aza-Henry reactions. 16th European Symposium on Organic Chemistry (ESOC 2009), Praha, 12-16 juuli. 422.
18.04.2019

Artur Noole

https://www.etis.ee/CV/Artur_Noole/eng
25.04.1985
artur.noole@ttu.ee

Career

Institution(s) and position(s)
01.09.2010–31.01.2014   
Tallinn University of Technology , Faculty of Science, Department of Chemistry, Chair of Organic Chemistry, Researcher (0,25)
15.09.2008–31.08.2010   
Tallinn University of Technology , Faculty of Science, Department of Chemistry, Chair of Organic Chemistry, Technician (0,50)
01.01.2008–31.12.2008   
Other staff
 
 
Education
2010–2014   
Tallinn University of Technology, Doctor of Philosophy (chemistry)
2007–2010   
Tallinn University of Technology, Master`s degree in Natural Sciences
2004–2007   
Tallinn University of Technology, Bachelor`s degree in Natural Sciences

Qualifications

Academic degrees
Artur Noole, Doctor's Degree, 2014, (sup) Tõnis Kanger, Asymmetric Organocatalytic Synthesis of 3,3’- Disubstituted Oxindoles, Tallinn University of Technology Faculty of Science, Department of Chemistry, Chair of Organic Chemistry.
Artur Noole, Master's Degree, 2010, (sup) Tõnis Kanger, Vask (II) katalüütiline asümmeetriline Henry reaktsioon (Copper (II) catalyzed asymmetric Herny reaction), Tallinn University of Technology Faculty of Science, Department of Chemistry.
 
 
Honours & awards
2014, Artur Noole, 1st prize at the national student research competition at PhD level in Natural Sciences
2011, Artur Noole, TUT Development fund OÜ Bruker Baltics Scholarship
2011, Artur Noole, Best scientific article in exact sciences in TUT 2011: Noole, A.; Borissova, M.; Lopp, M.; Kanger, T. J. Org. Chem. 2011, 76, 1538.
 
 
Field of research
FIELD OF RESEARCH: 4. Natural Sciences and Engineering; 4.11. Chemistry and Chemical Technology; SPECIALITY: Organic synthesis
 
 

Projects in progress

Supervised dissertations

Publications

Category
Year
Publication
 
1.1.
2015
Kaasik, M.; Noole, A.; Reitel, K.; Järving, I.; Kanger, T. (2015). Organocatalytic Conjugate Addition of Cyclopropylacetaldehyde Derivatives to Nitro Olefins: en Route to β- and γ-Amino Acids. European Journal of Organic Chemistry, 8, 1745−1753.10.1002/ejoc.201403387.
1.1.
2014
Preegel, G.; Noole, A.; Ilmarinen, K.; Järving, I.; Kanger, T.; Pehk, T.; Lopp, M. (2014). Enantioselective Organocatalytic Michael Addition of Cyclopentane-1,2-diones to Nitroolefins. Synthesis, 46 (19), 2595−2600.10.1055/s-0034-1378374.
1.1.
2014
Ošeka, M.; Noole, A.; Žari, S.; Öeren, M.; Lopp, M.; Kanger, T. (2014). Asymmetric Diastereoselective Synthesis of Spirocyclopropane Derivatives of Oxindole. European Journal of Organic Chemistry, 2014 (17), 3599−3606.
5.2.
2014
Preegel, G.; Noole, A.; Kanger, T.; Pehk, T.; Lopp, M. (2014). Enantioselective organocatalytic Michael addition of cyclopentane-1,2-diones to electrophiles. Balticum Organicum Syntheticum, Vilnius, Lithuania, July 6-9.
5.2.
2014
Noole, A.; Kanger, T.. (2014). Asymmetric synthesis of congested spiro-cyclopentaneoxindoles via an organocatalytic cascade reaction. 248th ACS National Meeting & Exposition, USA, San Fransisco, CA, 2014. American Chemical Society,.
5.2.
2014
Noole, A.; Ošeka, M.; Malkov, A.; Lopp, M.; Kanger, T. (2014). Asymmetric organocatalytic synthesis of spiro-cyclopropyloxindoles. Balticum Organicum Syntheticum: International Conference on Organic Synthesis 2014, Lithuania, Vilnius, July 6-9, 2014.
1.1.
2013
Noole, A.; Malkov, A. V.; Kanger, T.. (2013). Asymmetric Organocatalytic Synthesis of Spiro-cyclopropaneoxindoles. Synthesis, 45 (18), 2520−2524.
1.1.
2013
Noole, A.; Ilmarinen, K.; Järving, I.; Lopp, M.; Kanger, T. (2013). Asymmetric Synthesis of Congested Spiro-cyclopentaneoxindoles via an Organocatalytic Cascade Reaction. Journal of Organic Chemistry, 78 (16), 8117−8122.10.1021/jo4008223.
1.1.
2013
Noole, Artur; Ošeka, Maksim; Pehk, Tõnis; Öeren, Mario; Järving, Ivar; Elsegood, Mark; Malkov, Andrei; Lopp, Margus; Kanger, Tõnis. (2013). 3-Chlorooxindoles: Versatile Starting Materials for Asymmetric Organocatalytic Synthesis of Spirooxindoles. Advanced Synthesis and Catalysis, 355 (5), 829−835.
5.2.
2013
Preegel, G.; Noole, A.; Kanger, T.; Lopp, M. (2013). Enantioselective organocatalytic Michael addition of cyclopentane-1,2-diones to nitro olefins. ESOC 2013, Marseille, France, July 7-12.
1.1.
2012
Noole, A.; Suckman, N.; Kabeshov, M.; Kanger, T.; Macaev, F.; Malkov, A. (2012). Highly Enantio- and Diastereoselective Generation of Two Quaternary Centers in Spirocyclopropanation of Oxindole Derivatives. Chemistry - A European Journal, 18 (47), 14929−14933.10.1002/chem.201203099.
1.1.
2012
Noole, A.; Järving, I.; Werner, F.; Lopp, M.; Malkov, A.; Kanger, T. (2012).

Organocatalytic Asymmetric Synthesis of 3-Chlorooxindoles Bearing Adjacent Quaternary–Tertiary Centers

. Organic Letters, 14 (18), 4922−4925.10.1021/ol302245b.
1.1.
2012
Noole, A.; Pehk, T.; Järving, I.; Lopp, M.; Kanger, T. (2012). Organocatalytic asymmetric synthesis of trisubstituted pyrrolidines via a cascade reaction. Tetrahedron-Asymmetry, 23 (2), 188−198.10.1016/j.tetasy.2012.01.021.
1.1.
2011
Noole, A.; Borissova, M.; Lopp, M.; Kanger, T. (2011). Enantioselective Organocatalytic Aza-Ene-Type Domino Reaction Leading to 1,4-Dihydropyridines. Journal of Organic Chemistry, 76 (6), 1538−1545.10.1021/jo200095e.
1.1.
2010
Noole, A.; Lippur, K.; Metsala, A.; Lopp, M.; Kanger, T.. (2010). Enantioselective Henry Reaction Catalyzed by CuII Salt and Bipiperidine. Journal of Organic Chemistry, 75 (4), 1313−1316.10.1021/jo902664v.
5.2.
2009
Noole, A.; Kanger, T. (2009). Synthesis of 2-(2'-piperidinyl)pyridine derivatives and their use as ligands in asymmetric Henry and aza-Henry reactions. 16th European Symposium on Organic Chemistry (ESOC 2009), Praha, 12-16 juuli. 422.
18.04.2019
Detailne otsing
  • Leitud 5 kirjet
ProgrammLiikNumberNimiProjekti algusProjekti lõppVastutav täitjaAsutusFinantseerijapoolne rahastamine
ETFETF8289Efektiivsus organokatalüüsis 01.01.201031.12.2013Tõnis KangerTallinna Tehnikaülikool, Matemaatika-loodusteaduskond75 773,01 EUR
SFSF0140060s12Katalüütilise asümmeetriline sünteesi ja stereokeemilise analüüsi meetodid ja rakendused 01.01.201231.12.2013Margus LoppTallinna Tehnikaülikool, Matemaatika-loodusteaduskond285 640,00 EUR
ETFETF6662Kiraalsed diamiinid organokatalüütilistes ja metallkatalüütilistes asümmeetrilistes reaktsioonides01.01.200631.12.2009Tõnis KangerTallinna Tehnikaülikool, Matemaatika-loodusteaduskond37 052,41 EUR
IUTIUT19-32Suunatud asümmeetriline katalüütiline süntees: kompleksne integreeritud käsitlus01.01.201431.12.2019Margus LoppTallinna Tehnikaülikool, Matemaatika-loodusteaduskond; Tallinna Tehnikaülikool, Loodusteaduskond, Keemia ja biotehnoloogia instituut1 248 000,00 EUR
SFSF0142725s06Uued asümmeetrilise sünteesi strateegiad ja meetodid01.01.200631.12.2011Margus LoppTallinna Tehnikaülikool, Matemaatika-loodusteaduskond749 371,30 EUR