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Ats Metsis

https://www.etis.ee/CV/Ats_Metsis/est
21.05.1961

Teenistuskäik

Töökohad ja ametid
01.01.2016–...   
Testsystems OÜ, vabakutseline konsultant (1,00)
01.05.2015–30.09.2015   
Tervisetehnoloogiate Arenduskeskus AS (endine Reproduktiivmeditsiini TAK AS) , Teadur (1,00)
01.11.2012–30.11.2014   
Tervisetehnoloogiate Arenduskeskus AS (endine Reproduktiivmeditsiini TAK AS) , Teadur (1,00)
02.02.2009–30.10.2011   
Cellin Technologies OÜ, teadus arendus spetsialist,(EAS fiantseering) (1,00)
01.10.2007–31.12.2008   
Karolinska Institutet, MBB, MolNeuro, Külalisteadur (1,00)
01.05.2005–30.09.2007   
Genizon Svenska AB, Vanemteadur (1,00)
01.12.2000–30.04.2005   
Global Genomics AB, Vanemteadur (1,00)
19.06.2000–30.11.2000   
Karolinska Institutet, MBB, MolNeuro, Külalisteadur (1,00)
01.09.1999–31.12.2000   
Bioloogia õppetool, Dotsent (0,20)
01.09.1998–31.12.2000   
Tallinna Tehnikaülikool, Matemaatika-loodusteaduskond, Geenitehnoloogia instituut, Dotsent (0,20)
01.09.1996–31.03.1998   
Tallinna Tehnikaülikool, Matemaatika-loodusteaduskond, Geenitehnoloogia instituut, Vanemteadur (1,00)
01.09.1996–10.01.2001   
Keemilise ja Bioloogilise Füüsika Instituut, Vanemteadur (1,00)
01.07.1995–31.08.1996   
Keemilise ja Bioloogilise Füüsika Instituut, Teadur (1,00)
01.05.1992–30.06.1995   
Eksperimentaal Bioloogia Instituut, Teadur (1,00)
15.05.1991–15.05.1992   
Eksperimentaal Biologia Instituut, Protozooloogia osakond, Osakonna juhataja (1,00)
01.11.1988–15.05.1992   
Eksperimentaal Bioloogia Instituut, Teadur (1,00)
 
 
Haridustee
01.09.1984–31.12.1987   
aspirant, NSVL TA Tsütoloogia Instituut
01.09.1979–20.07.1984   
Leningradi Riiklik Ülikool (St. Peterburi Riiklik Ülikool), Bioloogia ja mullateaduste teaduskond
01.09.1968–30.06.1979   
Tallinna 7. Kekskkool
 
 
Lisainfo
Täiendkoolitused:
Dets. 2002 Practical project management course, Wenell AB, Göteborg
Mai 1993 II Nordic Training Course in Parasitic Zoonoses, Kopenhaahen, Taani
Mai 1993- Mai 1995 postdoc, Staten Serum Instiut, Kopenhaagen, Taani
1991-1992 kokku 2 kuud Bonni Ülikooli Zooloogi Inst, Saksamaa

Kvalifikatsioon

Teaduskraadid
Ats Metsis, doktorikraad, 1988, (juh) Tamara Vladimirovna Beyer, Цитологические исследования тканевых цист Sarcocystis bovicanis (Sarcocystis bovicanis'e koetsüstide tsütoloogilised uuringud), NSVL Teaduste Akadeemia Tsütoloogia Instituut.
 
 
Teadustöö põhisuunad
ETIS KLASSIFIKAATOR: 1. Bio- ja keskkonnateadused; 1.12. Bio- ja keskkonnateadustega seotud uuringud, näiteks biotehnoloogia, molekulaarbioloogia, rakubioloogia, biofüüsika, majandus- ja tehnoloogiauuringud; CERCS KLASSIFIKAATOR: T490 Biotehnoloogia ; TÄPSUSTUS: metagenoomika meetodite arendu ja valdkonlikud uuringud
 
 
Lisainfo
Aastast 2000 olen töötanud eraõiguslikes biotehnoloogia ettevõtetes, kus olen olnud hõivatud teadus arendus tegevusega metagenoomika, immunoloogia, uue põlvkonna järjestus meetodite arendamise, gloobaalse geeni ekspressiooni meetodite arendamise, jne valdkondades ja ka arendus tegevuse juhtimisega otseselt projekti juhtimise eest vastutades

Publikatsioonid

Klass
Aasta
Publikatsioon
 
1.1.
2008
Pihlak, Arno; Baurén, Göran; Hersoug, Ellef; Lönnerberg, Peter; Metsis, Ats; Linnarsson, Sten (2008). Rapid genome sequencing with short universal tiling probes. Nature Biotechnology, 26 (6), 676−684. DOI: 10.1038/nbt1405.
1.1.
2004
Metsis, Ats; Andersson, Ulf; Baurén, Göran; Ernfors, Patrik; Lönnerberg, Peter; Montelius, Andreas; Oldin, Mats; Pihlak, Arno; Linnarsson, Sten (2004). Whole-genome expression profiling through fragment display and combinatorial gene identification. Nucleic Acids Research, 32 (16), e127−e127.
3.1.
2003
A.Metsis; A.Jõgiste; R.Virbeliene; L.Jurevica (2003). Prevalence of parasites in the Baltic states (Estonia, Latvia, and Lithuania): epidemiology past and present. In: H. Akuffo et al. (_EditorsAbbr). Parasites of the Colder Climates (45−57). London, N.Y.: Taylor & Francis Ltd.
1.1.
1996
Harning, D; Spenter, J; Metsis, A; Vuust, J; Petersen, E (1996). Recombinant Toxoplasma gondii surface antigen 1 (P30) expressed in Escherichia coli is recognized by human Toxoplasma-specific immunoglobulin M (IgM) and IgG antibodies. Clinical and diagnostic laboratory immunology, 3 (3), 355−357.
1.1.
1995
Metsis, A; Pettsersen, E; Petersen, E (1995). Toxoplasma gondii: characterization of a monoclonal antibody recognizing antigens of 36 and 38 kDa with acid phosphatase activity located in dense granules and rhoptries. Experimental Parasitology, 81 (4), 472−479.
1.2.
1993
Metsis, Ats; (1993). Localization of acid phosphatase in the rhoptries of Sarcocystis cruzi. Bulletin of the Scandinavian Society for Parasitology, 3 (1), 23−25.
1.2.
1990
Metsis A. (1990). A light and electron microscopic study of degenerating Sarcocystis bovicanis tissue cyst from bovine heart. Proceedings of the Estonian Academy of Sciences, 39 (4), 280−281.
1.2.
1990
Metsis A. (1990). A cytochemical study of some phosphatases in tissue cysts of Sarcocystis bovicanis from bovine heart. Proc. Estonian Acad. Sci. Biol., 1990, 39, (4), 237-241. Proceedings of the Estonian Academy of Sciences, 39 (4), 237−241.
1.1.
1988
Metsis, A L (1988). [Cytochemical research on cysts of the sarcosporidian Sarcocystis bovicanis. II. Oxidation-reduction enzymes]. Tsitologiia, 30 (7), 882−887.
1.1.
1988
Metsis, A L; Rozanov, Iu M (1988). [Heterogeneity of the cellular composition of the cyst stages of the sarcosporidian Sarcocystis bovicanis studied by flow cytometry]. Tsitologiia, 30 (1), 62−68.
1.1.
1987
Metsis, A L (1987). Cytochemical study of the cysts of the sarcosporidian Sarcocystis bovicanis. I. Nucleic acids, polysaccharides, lipids and proteins. Tsitologiia, 29 (8), 955−962.

Tööstusomand

8.05.2018

Ats Metsis

https://www.etis.ee/CV/Ats_Metsis/eng
21.05.1961
atsmetsis@gmail.ee

Career

Institutions and positions
01.01.2016–...   
Testsystems OÜ, self employed consultant (1,00)
01.05.2015–30.09.2015   
Competence Centre on Health Technologies, Researcher (1,00)
01.11.2012–30.11.2014   
Competence Centre on Health Technologies, Researcher (1,00)
02.02.2009–30.10.2011   
Cellin Technologies Ltd, R&D specialist financed by Enterprise Estonia (1,00)
01.10.2007–31.12.2008   
Karolinska Institutet, MBB, MolNeuro, Karolinska Institutet, visiting scientist (1,00)
01.05.2005–30.09.2007   
Genizon Svenska AB, Senior scientist (1,00)
01.12.2000–30.04.2005   
Global Genomics AB, Senior scientist (1,00)
19.06.2000–30.11.2000   
Karolinska Institutet, MBB, MolNeuro, visiting scientist (1,00)
01.09.1999–31.12.2000   
Bioloogia õppetool, Associate Professor (0,20)
01.09.1998–31.12.2000   
Tallinn University of Technology , Faculty of Science, Department of Gene Technology, Associate Professor (0,20)
01.09.1996–31.03.1998   
Tallinn University of Technology , Faculty of Science, Department of Gene Technology, Senior Researcher (1,00)
01.09.1996–10.01.2001   
National Institute of Chemical Physics and Biophysics, Senior Researcher (1,00)
01.07.1995–31.08.1996   
National Institute of Chemical Physics and Biophysics, Researcher (1,00)
01.05.1992–30.06.1995   
Eksperimentaal Bioloogia Instituut, Researcher (1,00)
15.05.1991–15.05.1992   
Eksperimentaal Biologia Instituut, Protozooloogia osakond, head of deparment (1,00)
01.11.1988–15.05.1992   
Eksperimentaal Bioloogia Instituut, Researcher (1,00)
 
 
Education
01.09.1984–31.12.1987   
PhD student, Inst . of Cytology of the Acad. of Sci. of the USSR
01.09.1979–20.07.1984   
Leningrad (St.Petersburg) State University, faculty of biology and soil sciences
01.09.1968–30.06.1979   
Tallin Secondary School No 7
 
 
Additional information
Professional training:
Dec. 2002 Applied Project Management course by Wenell AB, Gothenburg
May 1993 II Nordic Training Course in Parasitic Zoonoses, Copenhagen, Denmark
May 1993-April 1995 postdoc at Statens Serum Institut, Copenhagen, Denmark
1991-1992 2 months at the Institute of Zoology of the Bonn University, Germany

Qualifications

Academic degrees
Ats Metsis, Doctor's Degree, 1988, (sup) Tamara Vladimirovna Beyer, Цитологические исследования тканевых цист Sarcocystis bovicanis (Cytological studies Sarcocystis bovicanis tissue cysts), Institute of Cytology of the Academy of Sciences of the USSR.
 
 
Fields of research
ETIS CLASSIFICATION: 1. Biosciences and Environment; 1.12. Biotechnology, Molecular Biology, Cell Biology, Biophysics and Economic and Technological Research relating to Bio- and Environmental Sciences; CERCS CLASSIFICATION: T490 Biotechnology ; SPECIFICATION: metagenomis methods development and research in the relevant fields
 
 
Additional information
Since 2000 I have been employed by various private biotech companies being involved with R&D activities in metagenomic, immunology, NGS sequencing, global gene expression etc. Been also involved with supervision of R&D ctivities as a practical project manager.

Publications

Category
Year
Publication
 
1.1.
2008
Pihlak, Arno; Baurén, Göran; Hersoug, Ellef; Lönnerberg, Peter; Metsis, Ats; Linnarsson, Sten (2008). Rapid genome sequencing with short universal tiling probes. Nature Biotechnology, 26 (6), 676−684. DOI: 10.1038/nbt1405.
1.1.
2004
Metsis, Ats; Andersson, Ulf; Baurén, Göran; Ernfors, Patrik; Lönnerberg, Peter; Montelius, Andreas; Oldin, Mats; Pihlak, Arno; Linnarsson, Sten (2004). Whole-genome expression profiling through fragment display and combinatorial gene identification. Nucleic Acids Research, 32 (16), e127−e127.
3.1.
2003
A.Metsis; A.Jõgiste; R.Virbeliene; L.Jurevica (2003). Prevalence of parasites in the Baltic states (Estonia, Latvia, and Lithuania): epidemiology past and present. In: H. Akuffo et al. (_EditorsAbbr). Parasites of the Colder Climates (45−57). London, N.Y.: Taylor & Francis Ltd.
1.1.
1996
Harning, D; Spenter, J; Metsis, A; Vuust, J; Petersen, E (1996). Recombinant Toxoplasma gondii surface antigen 1 (P30) expressed in Escherichia coli is recognized by human Toxoplasma-specific immunoglobulin M (IgM) and IgG antibodies. Clinical and diagnostic laboratory immunology, 3 (3), 355−357.
1.1.
1995
Metsis, A; Pettsersen, E; Petersen, E (1995). Toxoplasma gondii: characterization of a monoclonal antibody recognizing antigens of 36 and 38 kDa with acid phosphatase activity located in dense granules and rhoptries. Experimental Parasitology, 81 (4), 472−479.
1.2.
1993
Metsis, Ats; (1993). Localization of acid phosphatase in the rhoptries of Sarcocystis cruzi. Bulletin of the Scandinavian Society for Parasitology, 3 (1), 23−25.
1.2.
1990
Metsis A. (1990). A light and electron microscopic study of degenerating Sarcocystis bovicanis tissue cyst from bovine heart. Proceedings of the Estonian Academy of Sciences, 39 (4), 280−281.
1.2.
1990
Metsis A. (1990). A cytochemical study of some phosphatases in tissue cysts of Sarcocystis bovicanis from bovine heart. Proc. Estonian Acad. Sci. Biol., 1990, 39, (4), 237-241. Proceedings of the Estonian Academy of Sciences, 39 (4), 237−241.
1.1.
1988
Metsis, A L (1988). [Cytochemical research on cysts of the sarcosporidian Sarcocystis bovicanis. II. Oxidation-reduction enzymes]. Tsitologiia, 30 (7), 882−887.
1.1.
1988
Metsis, A L; Rozanov, Iu M (1988). [Heterogeneity of the cellular composition of the cyst stages of the sarcosporidian Sarcocystis bovicanis studied by flow cytometry]. Tsitologiia, 30 (1), 62−68.
1.1.
1987
Metsis, A L (1987). Cytochemical study of the cysts of the sarcosporidian Sarcocystis bovicanis. I. Nucleic acids, polysaccharides, lipids and proteins. Tsitologiia, 29 (8), 955−962.

Industrial property

8.05.2018

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PublikatsioonAutoridAastaVäljaande pealkiriKlassifikaatorFailAsutused
Rapid genome sequencing with short universal tiling probes.Pihlak, Arno; Baurén, Göran; Hersoug, Ellef; Lönnerberg, Peter; Metsis, Ats; Linnarsson, Sten2008Nature Biotechnology1.1.
Whole-genome expression profiling through fragment display and combinatorial gene identification.Metsis, Ats; Andersson, Ulf; Baurén, Göran; Ernfors, Patrik; Lönnerberg, Peter; Montelius, Andreas; Oldin, Mats; Pihlak, Arno; Linnarsson, Sten2004Nucleic Acids Research1.1.
Prevalence of parasites in the Baltic states (Estonia, Latvia, and Lithuania): epidemiology past and presentA.Metsis; A.Jõgiste; R.Virbeliene; L.Jurevica 2003Parasites of the Colder Climates3.1.
Recombinant Toxoplasma gondii surface antigen 1 (P30) expressed in Escherichia coli is recognized by human Toxoplasma-specific immunoglobulin M (IgM) and IgG antibodies.Harning, D; Spenter, J; Metsis, A; Vuust, J; Petersen, E1996Clinical and Diagnostic Laboratory Immunology1.1.
Toxoplasma gondii: characterization of a monoclonal antibody recognizing antigens of 36 and 38 kDa with acid phosphatase activity located in dense granules and rhoptries.Metsis, A; Pettsersen, E; Petersen, E1995Experimental Parasitology1.1.
Localization of acid phosphatase in the rhoptries of Sarcocystis cruzi.Metsis, Ats;1993Bulletin of the Scandinavian Society for Parasitology1.2.
A light and electron microscopic study of degenerating Sarcocystis bovicanis tissue cyst from bovine heart.Metsis A.1990Proc. Estonian Acad. Sci Biol.1.2.
A cytochemical study of some phosphatases in tissue cysts of Sarcocystis bovicanis from bovine heart. Proc. Estonian Acad. Sci. Biol., 1990, 39, (4), 237-241 Metsis A.1990Proceedings of the Estonian Academy of Sciences1.2.
[Cytochemical research on cysts of the sarcosporidian Sarcocystis bovicanis. II. Oxidation-reduction enzymes].Metsis, A L1988Tsitologiia1.1.
[Heterogeneity of the cellular composition of the cyst stages of the sarcosporidian Sarcocystis bovicanis studied by flow cytometry].Metsis, A L; Rozanov, Iu M1988Tsitologiia1.1.
Cytochemical study of the cysts of the sarcosporidian Sarcocystis bovicanis. I. Nucleic acids, polysaccharides, lipids and proteinsMetsis, A L1987Tsitologiia1.1.