14.08.1949
+358 50 3793211
atso.raasmaja@helsinki.fi

Career

Institutions and positions
2015–31.12.2019   
University of Tartu, Faculty of Medicine, Institute of Biomedicine and Translational Medicine, Faculty of Medicine (1,00)
01.04.2014–31.12.2019   
University of Tartu, Faculty of Medicine, Professor (1,00)
01.04.2014–31.03.2015   
University of Tartu, Faculty of Medicine, Institute of Biomedicine and Translational Medicine, Visiting Professor (0,50)
 
 
Education
01.09.2017–...   
Professor Emeritus
01.01.1997–...   
Docent in Pharmacology
1997–...   
Docent Animal and Cell Physiology
01.01.1990–...   
PhD (Doctor of Philosophy), ZoophysiologyAcademic degree: Doctor of Philosophy in Animal Physiology (1990) The title of theses: Alpha1 and Beta Adrenergic Receptors in Brown Adipose Tissue and the Adrenergic Regulation of Thyroxine 5'-Deiodinase. Supervisors: Professor Jan Nedergaard and Professor Nina Mohell. University of Stockholm
2012–31.08.2017   
Professor, Medicinal Toxicology; Docent (Pharmacology; Animal and Cell Physiology), PhD (Zoophysiology)
1987–31.12.1994   
Postdoctoral training in Harvard Medical School, Bosoton, USA, MacGill University Montreal Canada, Pennington Biomedical Resaerch Institute, Baton Rouge, Louisiana, USA, and in Pharmaceutical Industry
 
 
R&D related managerial and administrative work
1982−...   
Several committees and boards at the universities; Teaching, education material, supervision, evaluation, degrees and other academic issues
 
 
Creative work
Research at the university/academic institutes and pharmaceutical industry:
Projects e.g. in pharmacology and physiology of energy homeostasis, energy expenditure, eating behavior, addiction, obesity and eating disorders; brain degeneration, gene therapy and Parkinson's disease; cell death, apoptosis and cancer; adipose tissue and brain physiology and pharmacology; disease models and drug development, neural, brain and endocrine signalling systems.
Funding from Research Foundations for the proejcts and PhD students e.g. 1) Alcohol Research Foundation, to study the brain dopamine and opioid mechanisms of addiction in alcohol and game models, 2) Swedish Cultural Foundation and Finnish Cultural Foundation in Finland, to study the mechanisms of apoptosis in cell culture models,3)Guangzhou Green Life Pharmaceutical Ltd., China, to study the mechanisms of obesity and food intake..
 
 
Additional information
Main important activities in last 10 years listed below.;
2012-17, Professor in Medicinal Toxicology, Division of Pharmacology and Pharmacotherapy, University of Helsinki, Finland;
2009 Nomination of EMEA Expert, European Medicines Agency (London, U.K.) and National
Agency for Medicines (Helsinki, Finland)
;
2008-2018 Memberships in Finnish Society for Pharmacology, Finnish Society for Toxicology, Finnish Society for Gene Therapy and Finnish Society for Obesity Studies;
2008-2018 Activity as opponent and reviewer in several PhD dissertations, theses pre-examinations, docentship approvals and evaluation of pedagogic competence.;
2008-2018 Activity as a referee in several scientific peer reviewed journals and in national and international application evaluations.;
2008-2018 Activity as supervisor for 11 PhD theses, 10 MSc theses and appr. 20 BSc theses.;
2008-2018 Member or vice member in several boards and committees as e.g. Vice member of the Collegial Body of University of Helsinki (2010-14), Member and Faculty Representative in the Committee for Swedish Language Teaching University Helsinki (2016-17) and Member and vice member in the Board of The Pharmaceutical Learning Centre, Helsinki (2005-2008)
;
2008-2018 Pedagogic activity in lectures, examinations, evaluations and pedagogic development in e.g. pharmacology, toxicology, physiology and biosciences. In addition, participation as a cowriter in the pharmacology textbook for e.g. pharmacy and medicine students. ;

Qualifications

 
 
Honours & awards
2012, Atso Ilari Raasmaja, Granted for excellent research project by University of Helsinki research evaluations, as a member and principal investigator of CNS Research Group, lead by prof. Raimo Tuominen, Division of Pharmacology and Toxicology, Faculty of Pharmacy.
2004, Atso Ilari Raasmaja, Award for best thesis. Graduate school of Pharmacy granted one of the doctoral students in the gene therapy project, M.Sc. Pasi Lampela, for the best thesis in 2004 in the Faculty of Pharmacy. The main supervisor of Pasi Lampela’s thesis was docent Atso Raasmaja.
2002, Atso Ilari Raasmaja, Finnish Innovation Foundation, Espoo, Finland, to docent Atso Raasmaja for investigations of gene therapy being among the best Finnish innovations. Granted by Runar Bäckström's Foundation, Espoo, Finland. Department of Pharmacology and Toxicology, University of Kuopio, Finland
1990, Atso Ilari Raasmaja, Award to the best thesis. Awarded by The Faculty of Natural Sciences, University of Stockholm to M.Sc. Atso Raasmaja for best thesis at the faculty in 1989/90. Granted by Society of Stockholm High Schools, Stockholm, Sweden. Department of Metabolic Research, University of Stockholm.
 
 
Fields of research
ETIS CLASSIFICATION: 3. Health; 3.1. Biomedicine; CERCS CLASSIFICATION: B470 Physiology ; SPECIFICATION: Physiology, Pharmacology, Toxicology in energy homeostasis, brain degeneration apoptosis, and related disorders
 
 
Additional information
- Professonal teacher education in biology and health science, University of Joensuu, Finland
- Diploma of Professional Development in University Pedagogy, Univ of Kuopio
- Diploma of Professional Educational Administration (Opetushallinnon tutkinto), National Board of
Education (Helsinki, Finland)
- Nomination of EMEA Expert, European Medicines Agency (London, U.K.) and National Agency for Medicines (Helsinki, Finland)
Academic degree:
Doctor of Philosophy in Animal Physiology (1990)
The title of theses: Alpha1 and Beta Adrenergic Receptors in Brown Adipose Tissue and the Adrenergic Regulation of Thyroxine 5'-Deiodinase.
Supervisors: Professor Jan Nedergaard and Professor Nina Mohell.
University of Stockholm

Supervision of postdoctoral researchers

  • 01.01.2008−...    Some visiting and/or collaborating researchers  "Pharmacology, toxicology and Physiology" (Universities of Helsinki, Kuopio and Stockholm)

Publications

Category
Year
Publication
 
1.1.
2018
1.1.
2018
1.1.
2017
1.1.
2016
1.1.
2016
1.1.
2016
5.1.
2014
1.1.
2013
1.1.
2013
1.1.
2013
1.1.
2013
1.1.
2012
1.1.
2012
5.1.
2012
1.1.
2011
1.1.
2011
1.1.
2011
5.1.
2008
1.1.
2007
1.1.
2003
1.1.
2001
1.1.
1995
1.1.
1995
1.1.
1991
1.1.
1991
1.1.
1990
1.1.
1989
1.1.
1987
3.1.
1986
3.1.
1985
1.1.
1984
1.1.
1984
1.04.2019
14.08.1949
+358 50 3793211
atso.raasmaja@helsinki.fi

Teenistuskäik

Töökohad ja ametid
2015–31.12.2019   
Tartu Ülikool, Meditsiiniteaduste valdkond, bio- ja siirdemeditsiini instituut, Faculty of Medicine (1,00)
01.04.2014–31.12.2019   
Tartu Ülikool, Meditsiiniteaduste valdkond, Visiting professor (1,00)
01.04.2014–31.03.2015   
Tartu Ülikool, Meditsiiniteaduste valdkond, bio- ja siirdemeditsiini instituut, Külalisprofessor (0,50)
 
 
Haridustee
01.09.2017–...   
Medicinal Toxicology
01.01.1997–...   
Docent in Pharmacology
1997–...   
Docent Animal and Cell Physiology
01.01.1990–...   
PhD (Doctor of Philosophy), Zoophysiology, Academic degree: Doctor of Philosophy in Animal Physiology (1990) The title of theses: Alpha1 and Beta Adrenergic Receptors in Brown Adipose Tissue and the Adrenergic Regulation of Thyroxine 5'-Deiodinase. Supervisors: Professor Jan Nedergaard and Professor Nina Mohell. University of Stockholm
2012–31.08.2017   
Professor, Medicinal Toxicology; Docent (Pharmacology; Animal and Cell Physiology), PhD (Zoophysiology)
1987–31.12.1994   
Postdoctoral training in Harvard Medical School, Bosoton, USA, MacGill University Montreal Canada, Pennington Biomedical Resaerch Institute, Baton Rouge, Louisiana, USA, and in Pharmaceutical Industry
 
 
Teadusorganisatsiooniline ja -administratiivne tegevus
1982−...   
Several committees and boards at the universities; Teaching, education material, supervision, evaluation, degrees, and other academic issues
 
 
Loometöö
Research at the university/academic institutes and pharmaceutical industry:
Projects e.g. in pharmacology and physiology of energy homeostasis, energy expenditure, eating behavior, addiction, obesity and eating disorders; brain degeneration, gene therapy and Parkinson's disease; cell death, apoptosis and cancer; adipose tissue and brain physiology and pharmacology; disease models and drug development, neural, brain and endocrine signalling systems.

Funding from Research Foundations for the proejcts and PhD students e.g. 1) Alcohol Research Foundation, to study the brain dopamine and opioid mechanisms of addiction in alcohol and game models, 2) Swedish Cultural Foundation and Finnish Cultural Foundation in Finland, to study the mechanisms of apoptosis in cell culture models,3)Guangzhou Green Life Pharmaceutical Ltd., China, to study the mechanisms of obesity and food intake..
 
 
Lisainfo
Main important activities in last 10 years listed below.;
2012-17, Professor in Medicinal Toxicology, Division of Pharmacology and Pharmacotherapy, University of Helsinki, Finland;
2009 Nomination of EMEA Expert, European Medicines Agency (London, U.K.) and National Agency for Medicines (Helsinki, Finland)
;
2008-2018 Memberships in Finnish Society for Pharmacology, Finnish Society for Toxicology, Finnish Society for Gene Therapy and Finnish Society for Obesity Studies

;
2008-2018 Activity as opponent and reviewer in several PhD dissertations, theses pre-examinations, docentship approvals and evaluation of pedagogic competence.;
2008-2018 Activity as a referee in several scientific peer reviewed journals and in national and international application evaluations.;
2008-2018 Activity as supervisor for 11 PhD theses, 10 MSc theses and appr. 20 BSc theses.;
2008-2018 Member or vice member in several boards and committees as e.g. Vice member of the Collegial Body of University of Helsinki (2010-14), Member and Faculty Representative in the Committee for Swedish Language Teaching University Helsinki (2016-17) and Member and vice member in the Board of The Pharmaceutical Learning Centre, Helsinki (2005-2008)
;
2008-2018 Pedagogic activity in lectures, examinations, evaluations and pedagogic development in e.g. pharmacology, toxicology, physiology and biosciences. In addition, participation as a cowriter in the pharmacology textbook for e.g. pharmacy and medicine students. ;

Kvalifikatsioon

 
 
Teaduspreemiad ja tunnustused
2012, Atso Ilari Raasmaja, Granted for excellent research project by University of Helsinki research evaluations, as a member and principal investigator of CNS Research Group, lead by prof. Raimo Tuominen, Division of Pharmacology and Toxicology,Faculty of Pharmacy.
2004, Atso Ilari Raasmaja, Award for best thesis. Graduate school of Pharmacy granted one of the doctoral students in the gene therapy project, M.Sc. Pasi Lampela, for the best thesis in 2004 in the Faculty of Pharmacy. The main supervisor of Pasi Lampela’s thesis was docent Atso Raasmaja.
2002, Atso Ilari Raasmaja, 2002 Award to the research innovation. Awarded by The Finnish Innovation Foundation, Espoo, Finland, to docent Atso Raasmaja for investigations of gene therapy being among the best Finnish innovations. Granted by Runar Bäckström's Foundation, Espoo, Finland. Department of Pharmacology and Toxicology, University of Kuopio, Finland
1990, Atso Ilari Raasmaja, Award to the best thesis. Awarded by The Faculty of Natural Sciences, University of Stockholm to M.Sc. Atso Raasmaja for best thesis at the faculty in 1989/90. Granted by Society of Stockholm High Schools, Stockholm, Sweden. Department of Metabolic Research, University of Stockholm.
 
 
Teadustöö põhisuunad
ETIS KLASSIFIKAATOR: 3. Terviseuuringud; 3.1. Biomeditsiin; CERCS KLASSIFIKAATOR: B470 Füsioloogia ; TÄPSUSTUS: Physiology, Pharmacology, Toxicology in energy homeostasis, brain degeneration apoptosis, and related disordersisorders and drug development
 
 
Lisainfo
- Professonal teacher education in biology and health science, University of Joensuu, Finland
- Diploma of Professional Development in University Pedagogy, Univ of Kuopio
- Diploma of Professional Educational Administration (Opetushallinnon tutkinto), National Board of
Education (Helsinki, Finland)
- Nomination of EMEA Expert, European Medicines Agency (London, U.K.) and National Agency for Medicines (Helsinki, Finland)
Academic degree:
Doctor of Philosophy in Animal Physiology (1990)
The title of theses: Alpha1 and Beta Adrenergic Receptors in Brown Adipose Tissue and the Adrenergic Regulation of Thyroxine 5'-Deiodinase.
Supervisors: Professor Jan Nedergaard and Professor Nina Mohell.
University of Stockholm

Juhendatud järeldoktorid

  • 01.01.2008−... Some visiting and/or collaborating researchers "Pharmacology, toxicology and Physiology" Universities of Helsinki, Kuopio and Stockholm

Publikatsioonid

Klass
Aasta
Publikatsioon
 
1.1.
2018
1.1.
2018
1.1.
2017
1.1.
2016
1.1.
2016
1.1.
2016
5.1.
2014
1.1.
2013
1.1.
2013
1.1.
2013
1.1.
2013
1.1.
2012
1.1.
2012
5.1.
2012
1.1.
2011
1.1.
2011
1.1.
2011
5.1.
2008
1.1.
2007
1.1.
2003
1.1.
2001
1.1.
1995
1.1.
1995
1.1.
1991
1.1.
1991
1.1.
1990
1.1.
1989
1.1.
1987
3.1.
1986
3.1.
1985
1.1.
1984
1.1.
1984
1.04.2019
  • Found 32 results
PublicationAuthorsYearSource titleClassificationFileInstitutions
Amphetamine primes enhanced motivation toward uncertain choices in rats with genetic alcohol preferenceOinio V, Sundström M, Bäckström P, Uhari-Väänänen J, Kiianmaa K, Raasmaja A, Piepponen P.2018Psychopharmacology1.1.University of Tartu
The κ-opioid receptor antagonist JDTic decreases ethanol intake in alcohol-preferring AA ratsUhari-Väänänen J, Raasmaja A, Bäckström P, Oinio V, Carroll FI, Airavaara M, Kiianmaa K, Piepponen P.2018Psychopharmacology1.1.University of Tartu
Dopaminergic modulation of reward-guided decision making in alcohol-preferring AA rats.Oinio V, Bäckström P, Uhari-Väänänen J, Raasmaja A, Piepponen P, Kiianmaa K. 2017Behavioural Brain Research1.1.University of Tartu
Accumbal mu-Opioid Receptors Modulate Ethanol Intake in Alcohol-Preferring Alko Alcohol RatsUhari-Vaananen, Johanna; Raasmaja, Atso; Backstrom, Pia; Oinio, Ville; Airavaara, Mikko; Piepponen, Petteri; Kiianmaa, Kalervo2016Alcoholism-clinical And Experimental Research1.1.University of Tartu
Analysis of metabolic effects of menthol on WFS1-deficient mice.Ehrlich, Marite; Ivask, Marilin; Raasmaja, Atso; Kõks, Sulev2016Physiological reports1.1.University of Tartu
Cellular Stress and p53-Associated Apoptosis by Juniperus communis L. Berry Extract Treatment in the Human SH-SY5Y Neuroblastoma CellsLantto, Tiina A; Laakso, Into; Dorman, HJ; Mauriala, Timo; Hiltunen, Raimo; Kõks, Sulev; Raasmaja, Atso2016International Journal of Molecular Sciences1.1.University of Tartu, Faculty of Medicine, Institute of Biomedicine and Translational Medicine
OPIOIDERGIC MODULATION OF ETHANOL INTAKE IN THE NUCLEUS ACCUMBENS OF ALCOHOL-PREFERRING AA RATSKiianmaa, K.; Uhari-Vaananen, J.; Airavaara, M.; Backstrom, P.; Oinio, V.; Raasmaja, A.; Piepponen, P.2014Alcohol And Alcoholism5.1.University of Tartu
A water-alcohol extract of Citrus grandis whole fruits has beneficial metabolic effects in the obese Zucker rats fed with high fat/high cholesterol dietRaasmaja, Atso; Lecklin, Anne; Li, Xiang Ming; Zou, Jianqiang; Zhu, Guo-Guang; Laakso, Into; Hiltunen, Raimo2013Food Chemistry1.1.University of Tartu
Catechol-O-Methyltransferase (COMT) Protein Expression and Activity after Dopaminergic and Noradrenergic Lesions of the Rat BrainSchendzielorz, Nadia; Oinas, Juha-Pekka; Myohanen, Timo T.; Reenila, Ilkka; Raasmaja, Atso; Mannisto, Pekka T.2013PLOS ONE1.1.University of Tartu
Gene therapy with AAV2-CDNF provides functional benefits in a rat model of Parkinson's diseaseBack, Susanne; Peranen, Johan; Galli, Emilia; Pulkkila, Paivi; Lonka-Nevalaita, Liina; Tamminen, Tuulia; Voutilainen, Merja H.; Raasmaja, Atso; Saarma, Mart; Mannisto, Pekka T.; Tuominen, Raimo K.2013Brain and Behavior1.1.University of Tartu
High correlation between in vivo [I-123]beta-CIT SPECT/CT imaging and post-mortem immunohistochemical findings in the evaluation of lesions induced by 6-OHDA in ratsBack, Susanne; Raki, Mari; Tuominen, Raimo K.; Raasmaja, Atso; Bergstrom, Kim; Mannisto, Pekka T.2013Ejnmmi Research1.1.University of Tartu
A Transient Inhibition and Permanent Lack of Catechol-O-Methyltransferase have Minor Effects on Feeding Pattern of Female RodentsSchendzielorz, Nadia; Mannisto, Pekka T.; Karayiorgou, Maria; Gogos, Joseph A.; Raasmaja, Atso2012Basic & Clinical Pharmacology & Toxicology1.1.University of Tartu
Minocycline protects SH-SY5Y cells from 6-hydroxydopamine by inhibiting both caspase-dependent and -independent programmed cell deathOssola, Bernardino; Lantto, Tiina A.; Puttonen, Katja A.; Tuominen, Raimo K.; Raasmaja, Atso; Mannisto, Pekka T.2012Journal of Neuroscience Research1.1.University of Tartu
Toxicity and apoptotic effects of selected compounds and extracts from edible plantsLantto, T. A.; Raasmaja, A.; Hiltunen, R.2012Planta Medica5.1.University of Tartu
Antioxidant, pro-oxidant and cytotoxic properties of parsleyDorman, H. J. Damien; Lantto, Tiina A.; Raasmaja, Atso; Hiltunen, Raimo2011Food & Function1.1.University of Tartu
Chronic infusion of CDNF prevents 6-OHDA-induced deficits in a rat model of Parkinson's diseaseVoutilainen, Merja H.; Back, Susanne; Peranen, Johan; Lindholm, Paivi; Raasmaja, Atso; Mannisto, Pekka T.; Saarma, Mart; Tuominen, Raimo K.2011Experimental Neurology1.1.University of Tartu
Mechanisms of polyethylenimine-mediated DNA delivery: free carrier helps to overcome the barrier of cell-surface glycosaminoglycansHanzlikova, Martina; Ruponen, Marika; Galli, Emilia; Raasmaja, Atso; Aseyev, Vladimir; Tenhu, Heikki; Urtti, Arto; Yliperttula, Marjo2011Journal Of Gene Medicine1.1.University of Tartu
Hormonal regulation of COMT activity in ratsSchendzielorz, N.; Rysa, A.; Raasmaja, A.; Reenila, I.; Mannisto, P. T.2008European Journal of Pharmaceutical Sciences5.1.University of Tartu, Faculty of Medicine, Institute of Biomedicine and Translational Medicine
Constitutive Ret activity in knock-in multiple endocrine neoplasia type B mice induces profound elevation of brain dopamine concentration via enhanced synthesis and increases the number of TH-positive cells in the substantia nigraMijatovic, Jelena; Airavaara, Mikko; Planken, Anu; Auvinen, Petri; Raasmaja, Atso; Piepponen, TP; Costantini, F; Ahtee, L; Saarma, M.2007Journal of Neuroscience1.1.University of Helsinki
Differen synergistic roles of small polyethylenimine and Dosper in gene delivery Lampela, P.; Elomaa, M.; Ruponen, M.; Urtti, A.; Männistö, P. T.; Raasmaja, A.2003Journal of Controlled Release1.1.University of Tartu
Efficient transfection of novel bovine papillomavirus 1 expression plasmidsLampela, P.; Ustav, E.; Ustav, M.; Niskanen, M.; Mannisto, PT.; Raasmaja, A.2001Plasmid1.1.University of Tartu
Effects of thyroid hormone on norepinehrine signal in brown adipose tissue. I: ß1 and ß2-adrenergic receptors and cyclic adenosine monophosphate generationAmalia Rubio, Atso Raasmaja, Ana Luiza Maia, Kiung-Rae Kim and J. Enrique Silva1995Endocrinology1.1.University of Tartu, Faculty of Medicine, Institute of Biomedicine and Translational Medicine
Thyroid hormone and norepinephrine signal in brown adipose tissue. II: differential effects of thyroid hormone on ß3-adrenergic receptors in brown and white adipose tissueAmalia Rubio, Atso Raasmaja and J. Enrique Silva1995Endocrinology1.1.University of Tartu, Faculty of Medicine, Institute of Biomedicine and Translational Medicine
Biochemical mechanisms of the novel cardiotonic agent OR-1259Atso Raasmaja, Antti Talo, Erkki Nissinen, Inge-Britt Linden and Pentti Pohto1991Journal of Molecular and Cellular Cardiology1.1.University of Tartu, Faculty of Medicine, Institute of Biomedicine and Translational Medicine
Triiodothyronine causes rapid reversal of alpha-1/cyclic monophosphate synergism on brown adipocyte respirationand type II deiodinase activityMichael Noronha, Atso Raasmaja, Norma Moolten and P. Reed Larsen1991Metabolism1.1.University of Tartu, Faculty of Medicine, Institute of Biomedicine and Translational Medicine