See veebileht kasutab küpsiseid kasutaja sessiooni andmete hoidmiseks. Veebilehe kasutamisega nõustute ETISe kasutustingimustega. Loe rohkem
Olen nõus
14.05.1945
+46706335597
+46907853351
gunnar.selstam@molbiol.umu.se
I have cooperated with University of Tartu (Dept of Anatomy and Histology, Dept of General and Molecular Pathology and Dept of Orthopedics) since 1993 and is very much interested in continuing. I have co-supervised 2 graduate students. They have learnt especially molecular biology methods and techniques at Umeå university and incorporated these results into their thesises. My swedish graduate students and project students have participated in graduate courses and microscopy techniques at Tartu university. Hence, from my own field, molecular biology, several methods and models have been introduced at Tartu university. My graduate students have learnt modern histologu techniques at Tartu university. This together with estonian publication list shows that the cooperation is very fruitful indeed. Since this research group and its tasks are very exciting and since I have terminated almost all assignments and only have one part-time graduate student, I can really devote my effort on the bone physiology research.

Career

Institutions and positions
01.01.1999–...   
Department of Molecular Biology, University of Umea, Sweden; full professor

Qualifications

 
 
Honours & awards
1987, Gunnar Selstam, Fernström Price (For scientific achievments)
 
 
Fields of research
ETIS CLASSIFICATION: 3. Health; 3.11. Biochemistry, Genetics, Microbiology, Biotechnology, Molecular Biology, Cell Biology, Biophysics and Bioinformatics relating to Health Studies
 
 
Additional information
20 selesctions of my original publications with short comments (1972-2008)

1. Ahrén, K., Jansson, P.O. and Selstam, G.:Perfusion of ovaries in vitro and in vivo. Acta Endocr. (Kbh) Suppl. 158, 285-309, 1972.
(A new method for perfusion of genital organs especially ovaries)

2. Rosberg, S., Selstam, G. and Isaksson, O.: Characterization of the metabolism of exogenous cyclic AMP by perfused rat heart and incubated prepubertal rat ovary. Acta Physiol.Scand. 94, 522-535, 1975.
(A novel and extremely rapid salvage pathway system for adenosine still not understood)

3. Selstam, G. and Rosberg, S.: Stimulatory effect of FSH in vitro on the extracellular active cyclic AMP phosphodiesterase in the prepubertal rat ovary. Acta Endocr.(Kbh) 81, 563-573, 1976.
(Exoenzymes can participate in cell function)

4. Damber, J-E., Selstam, G. and Wang, J.: Inhibitory effect of estradiol-17ß on human chorionic gonadotrophin induced increment of testicular blood flow and plasma testosterone concentration in rats. Biol.Reprod. 25, 555-559, 1981.
(Important knowledge for prostate cancer therapy)

5. Holm, S., Selstam, G. and Nachemsson, A.: Carbohydrate metabolism and concentration profiles of solutes in the canine lumbar intervertebral disc. Acta Physiol.Scand. 115, 147-156, 1982.
(First report in literature on the importance of and the delicate oxygen balance of the vertebrate disc)

6. Norjavaara, E., Selstam, G. and Ahrén, K.: Catecholamine stimulation of cyclic AMP and progesterone production in rat corpora lutea of different ages. Acta Endocr. 100, 613-622, 1982.
(Adrenalin may actually function as a stimulator in the ovary)

7. Damber, J-E., Lindahl, O., Selstam, G. and Tenland, T.: Rhythmical oscillations in rat testicular microcirculation as recorded by laser Doppler flowmetry. Acta Physiol.Scand. 118, 117-123, 1983.
(Showing laser Doppler flowmetry can be used for internal organs and that a remarkable oscillation occur in testicular capillaries)

8. Selstam, G. and Damber, J-E.: Measurement of blood flow to ventral prostate in the rat with radioactive microspheres: Effects of estradiol-17ß and human chorionic gonadotrophin. Acta Physiol.Scand. 119, 209-212, 1983.
(First report in literature of physiological blood flow in the prostate)

9. Gåfvels, M., Selstam, G. and Damber, J-E.: Influence of oxygen tension and substrates on basal and luteinizing hormone stimulated progestrone production and energy metabolism by isolated corpora lutea of adult pseudopregnant rats. Acta Physiologica Scandinavica, 130, 475-478, 1987.
(Energy regulation of the cell in the very demanding process of hormone production)

10. Gelander, L., Lindstedt, G., Selstam, G., Wide, L. and Albertsson-Wikland, K.: Effect of two growth hormone releasing hormones (GHRH 1-40 and 1-29) on serum growth hormone and other pituitary homones. Hormone Research, 31, 213-220, 1989.
(For drug companies this is an interesting paper showing the importance of expert evaluation – in this case the drug had to be stopped at the clinical trying stage because of a “simple” lack of knowledge)

11. Olofsson, J., Norjavaara, E. and Selstam, G.: In vivo levels of prostaglandin F2a, E2 and prostacyclin in the corpus luteum of pregnant and pseudopregnant rats. Biology of Reproduction, 42, 792-800, 1990.
(New method for prostaglandin determination and that locally procuced prostaglandinsd participate in luteolysis)

12. Gåfvels M, Bjurulf E, Selstam G 1992 Prolactin stimulates the expression of luteinizing hormone/chorionic gonadotropin receptor messenger ribonucleic acid in the rat corpus luteum and rescues early pregnancy from bromocriptin-induced abortion. Biol Reprod 47:534-540
(Major achievement: corpus luteum is not autonomous but instead regulated by gonadotropin receptor levels)

13. Dunkel L, Albertsson-Wikland K, Alfthan H, Stenman U, Selstam G and Rosberg S 1992 Developmental changes in 24-hour secretory profiles of luteinizing hormone and follicle stimulating hormone from prepuberty to late stages of puberty in boys. J Clin Endocrinol Metab 74:890-897
(Puberty starts long before the start of the growth spurt)

14. Nakata M, Selstam G, Olofsson J, Bäckström T 1992 Investigation of the human corpus luteum by ultrasonography: a proposed scheme for clinical investigation. Ultrasound Obstet Gynecol 2:190-196
(Showing that infertility due to corpus luteum failure can be diagnosed by ultra sound)

15. Bjurulf E, Selstam G. 1996 Rat luteinizing hormone receptor messenger ribonucleic acid expression and luteolysis: inhibition by prostaglandin F2 alpha. Biol Reprod. 54:1350-5.
(Major achievement: Corpus luteum function can be regulated by gonadotropin receptor levels)

16. Olofsson JI, Leung CH, Bjurulf E, Ohno T, Selstam G, Peng C, Leung PC. 1996 Characterization and regulation of a mRNA encoding the prostaglandin F2alpha receptor in the rat ovary. Mol Cell Endocrinol.123:45-52.
(This is the first report of the encoded F-receptor)

17. Albertsson-Wikland K, Rosberg S, Lannering B, Dunkel L, Selstam G, Norjavaara E. 1997 Twenty-four-hour profiles of luteinizing hormone, follicle-stimulating hormone, testosterone, and estradiol levels: a semilongitudinal study throughout puberty in healthy boys. J Clin Endocrinol Metab. 82:541-9.
(The biological clock regulating testosterone starts already during infancy)

18. Bjurulf E, Toffia O, Selstam G, Olofsson JI. 1998 Luteolysis induced by a prostaglandin F2alpha analogue occurs independently of prolactin in the rat. Biol Reprod. 59:17-21.
(Showing for first time that luteolysis=time of menstruation is due to downregulation of the gene for LH-receptor)

19. Arend A, Zilmer M, Vihalemm T, Selstam G, Sepp E. 2000 Lipoic acid prevents suppression of connective tissue proliferation in the rat liver induced by n-3 PUFAs. A pilot study. Ann Nutr Metab. 44:217-22.
(One of several articles in co-operation with Tartu Univ)

20. Gunnarsson D, Leffler P, Ekwurtzel E, Martinsson G, Liu K, Selstam G.2008
Mono-(2-ethylhexyl) phthalate stimulates basal steroidogenesis by a cAMP-independent mechanism in mouse gonadal cells of both sexes.
Reproduction. 135:693-703.
(Most common plastic constituent has direct effects on the reproductive function!)

Publications

Category
Year
Publication
 
1.1.
2010
1.1.
2010
5.2.
2010
1.1.
2009
1.1.
2007
1.1.
2007
1.1.
2005
1.2.
2005
1.3.
2005
5.2.
2005
1.1.
2004
5.2.
2004
5.2.
2004
1.2.
2003
5.2.
2003
5.2.
2003
3.4.
2001
3.4.
2001
1.1.
2000
3.4.
1999
5.2.
1999
18.06.2019

Otsi projekti

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Uus Frascati (2015)
Uus ja vana Frascati (otsing uue järgi väljastab ka seotud vanad)
Kõik
Käimasolevad
Lõppenud
Algus
Hajus
Täpne
  • Leitud 1 kirjet
ProgrammLiikNumberNimiProjekti algusProjekti lõppVastutav täitjaAsutusFinantseerijapoolne rahastamine
SFSF0180012s11Kõhr- ja luukoe formeerumise ja degeneratsiooni mehhanismid erinevate patoloogiate korral01.01.201131.12.2016Andres ArendTartu Ülikool, Arstiteaduskond402 000,00 EUR