Gunnar Tasa

https://www.etis.ee/CV/Gunnar_Tasa/est

Teenistuskäik

Haridustee
Kõrgem, lõpetanud arstiteaduskonna ravi eriala 1991
 
 
Teadusorganisatsiooniline ja -administratiivne tegevus
Olen Eesti Inimesegeneetika Ühingu juhatuse liige.
Kuulun Euroopa Ravimiameti (EMEA) geeniteraapia komiteesse.
1995.-ndal aastal käivitasin isikute molekulaargeneetilise identifitseerimise TÜ ÜMPI-s, millest koostöös Eesti Kohtuarstliku Ekspertiisibürooga sai aastal 2001 alguse kohtuarstlik DNA labor. Olen oma laboris käivitanud mõnede pärilike haiguste molekulaardiagnostika (pärilik hemokromatoos, UPD Angelman'i ja Prader-Willi sündroomide korral).

Kvalifikatsioon

Teaduskraadid
Gunnar Tasa, doktorikraad, 2004, (juh) Aavo-Valdur Mikelsaar, Polymorphic glutathione S-transferases - biology and role in modifying genetic susceptibility to senile cataract and primary open angle glaucoma., Tartu Ülikool, Arstiteaduskond.
 
 

Lõppenud projektid

18.04.2019

Gunnar Tasa

https://www.etis.ee/CV/Gunnar_Tasa/eng
737 4217
gunnar.tasa@ut.ee

Career

Institution(s) and position(s)
I have been working in the Department of Human Biology and Genetics since 1991 as an assistant and researcher. Research training:1) course of clinical and population genetics at the Erasmus University in Rotterdam 1992.a.; 2) course of genetics in 1993 in Helsinki; 3) research in the laboratory of genetics in Lund 1993.a.; 4) research in the laboratory of molecular genetics at the Institute of Occupational Health in Stockholm 1994/1995; 5) research in the laboratory of molecular genetics at the Institute of Occupational Health in 1995/1996.
 
 
Education
Higher, graduated from Medical Faculty of University of Tartu in 1991
 
 
R&D related managerial and administrative work
I am a member of the Board of Estonian Society of Human Genetics and also a member of Gene Therapy Expert Group of EMEA (European Agency for the Evaluation of Medicinal Products).
In 1995 I established a forensic DNA lab. The lab provides DNA services for Estonian police and also most paternity cases in Estonia are genotyped in this lab. I help to resolve the most complicated cases that occur in this forensic DNA lab.

Qualifications

Academic degrees
Gunnar Tasa, Doctor's Degree, 2004, (sup) Aavo-Valdur Mikelsaar, Polymorphic glutathione S-transferases - biology and role in modifying genetic susceptibility to senile cataract and primary open angle glaucoma., University of Tartu, Faculty of Medicine.
 
 
Additional information
PhD
University of Tartu 2004

Completed projects

Publications

Category
Year
Publication
 
1.1.
2005
Maron, E.; Lang, A.; Tasa, G.; Liivlaid, L.; Toru, I.; Must, A.; Vasar, V.; Shlik, J. (2005). Associations between serotonin-related gene polymorphisms and panic disorder. International Journal of Neuropsychopharmacology, 8 (2), 261−266.
1.1.
2005
Zetterberg, M.; Tasa, G.; Prince, JA.; Palmer, M.; Juronen, E.; Veromann, S.; Teesalu, P.; Karlsson, JO.; Blennow, K.; Zetterberg, H. (2005). Methylenetetrahydrofolate reductase genetic polymorphisms in patients with cataract. American Journal of Ophthalmology, 140 (5), 932−934.
1.1.
2004
Veromann, S.; Sunter, A.; Juronen, E.; Tasa, G.; Panov, A. (2004). Eye lens crystallins: A component of intraocular pseudoexfoliative material. Ophthalmic Research, 36 (1), 51−54.
1.1.
2004
Maron, E.; Tasa, G.; Toru, I.; Lang, A.; Vasar, V.; Shlik, J. (2004). Association between serotonin-related genetic polymorphisms and CCK-4-induced panic attacks with or without 5-hydroxytryptophan pretreatment in healthy volunteers. World Journal of Biological Psychiatry, 5 (3), 149−154.
1.1.
2004
Zetterberg, M.; Zetterberg, H.; Palmer, M.; Rymo, L.; Blennow, K.; Tasa, G.; Juronen, E.; Veromann, S.; Teesalu, P.; Zetterberg, M.; Karlsson, JO.; Hoglund, K. (2004). Apolipoprotein E polymorphism in patients with cataract. British Journal of Ophthalmology, 88 (5), 716−718.
5.1.
2004
Maron, E.; Tasa, G.; Toru, I.; Lang, A.; Vasar, V.; Shlik, J. (2004). Association between serotonin-related genetic polymorphisms and cholecystokinin tetrapeptide induced panic attacks in healthy volunteers. European Neuropsychopharmacology, 14, S125−S126.
5.1.
2004
Maron, E.; Tasa, G.; Toru, I.; Lang, A.; Vasar, V.; Shlik, J. (2004). Association between serotonin-related genetic polymorphisms and cholecystokinin tetrapeptide induced panic attacks in healthy volunteers. European Neuropsychopharmacology, 14, S14−S15.
1.1.
2003
Veromann, S.; Sunter, A.; Tasa, G.; Juronen, E.; Panov, A.; Pastak, M.; Kaljurand, K. (2003). Dietary sugar and salt represent real risk factors for cataract development. Ophthalmologica, 217 (4), 302−307.
1.1.
2002
Alexandrie, AK.; Rannug, A.; Juronen, E.; Tasa, G.; Warholm, M. (2002). Detection and characterization of a novel functional polymorphism in the GSTT1 gene. Pharmacogenetics, 12 (8), 613−619.
1.1.
2001
Parlist, P.; Mikelsaar, AV.; Tasa, G.; Beckman, L. (2001). The frequency of C282Y and H63D mutations in Hemochromatosis gene in native Estonians. European Journal of Epidemiology, 17 (3), 213−216.
1.1.
2001
Tasa, G.; Kals, J.; Muru, K.; Juronen, E.; Piirsoo, A.; Veromann, S.; Janes, S.; Mikelsaar, AV.; Lang, A. (2001). A novel mutation in the M1S1 gene responsible for gelatinous droplike corneal dystrophy. Investigative Ophtalmology & Visual Science, 42 (12), 2762−2764.
1.1.
2000
Juronen, E.; Tasa, G.; Veromann, S.; Parts, L.; Tiidla, A.; Pulges, R.; Panov, A.; Soovere, L.; Koka, K.; Mikelsaar, AV. (2000). Polymorphic glutathione S-transferase M1 is a risk factor of primary open-angle glaucoma among Estonians. Experimental Eye Research, 71 (5), 447−452.
1.1.
2000
Kalev, I.; Mikelsaar, AV.; Beckman, L.; Tasa, G.; Parlist, P. (2000). High frequency of the HIV-1 protective CCR5 Delta 32 deletion in native Estonians. European Journal of Epidemiology, 16 (12), 1107−1109.
5.1.
2000
Must, A.; Tasa, G.; Kreegipuu, K.; Muru, K.; Juronen, E.; Allik, J.; Lang, A. (2000). Association of personality patterns with genetic markers of the serotonergic system. American Journal of Medical Genetics, 96 (4), 510−510.
5.1.
1998
Mikelsaar, AV.; Beckman, L.; Tasa, G.; Parlist, P.; Mikelsaar, R. (1998). The frequency of hemochromatosis mutation C282Y in Estonian population. European Journal of Human Genetics, 6, 106−106.
1.1.
1997
Vlachodimitropoulos, D.; Norppa, H.; Autio, K.; Catalan, J.; Hirvonen, A.; Tasa, G.; Uuskula, M.; Demopoulos, NA.; Sorsa, M. (1997). GSTT1-dependent induction of centromere-negative and -positive micronuclei by 1,2:3,4-diepoxybutane in cultured human lymphocytes. Mutagenesis, 12 (5), 397−403.
1.1.
1996
Juronen, E.; Tasa, G.; Uuskula, M.; Pooga, M.; Mikelsaar, AV. (1996). Purification, characterization and tissue distribution of human class theta glutathione S-transferase T1-1. Biochemistry and Molecular Biology International, 39 (1), 21−29.
1.1.
1996
Tasa, G.; Juronen, E.; Viikmaa, M.; Tiidla, A.; Parlist, P.; Uuskula, M.; Kalev, I.; Mikelsaar, AV. (1996). Distribution of glutathione S-transferase T1 phenotypes in the Estonian population. Gene Geography, 10 (3), 181−189.
1.1.
1995
Tasa, G.; Uuskula, M.; Hirvonen, A.; Mikelsaar, AV. (1995). Optimization of pcr to yield successful amplification from heparin-contaminated dna. Methods in Molecular and Cellular Biology, 5 (2), 122−124.
1.1.
1995
Tasa, G.; Juronen, E.; Uuskula, M.; Viikmaa, M.; Mikelsaar, AV. (1995). Phenotyping of glutathione-s-transferase m1 in the Estonian population by elisa using gstm1a and gstm1b specific monoclonal-antibodies. Clinica Chimica Acta, 239 (2), 191−196.
1.1.
1995
Norppa, H.; Hirvonen, A.; Jarventaus, H.; Uuskula, M.; Tasa, G.; Ojajarvi, A.; Sorsa, M. (1995). Role of gstt1 and gstm1 genotypes in determining individual sensitivity to sister-chromatid exchange induction by diepoxybutane in cultured human-lymphocytes. Carcinogenesis, 16 (6), 1261−1264.
1.1.
1994
Juronen, E.; Tasa, G.; Uuskula, M.; Parik, J.; Mikelsaar, AV. (1994). Allele-specific monoclonal-antibodies against glutathione-s-transferase mu1-1. Hybridoma, 13 (6), 477−484.
1.1.
1994
Mikelsaar, AV.; Tasa, G.; Parlist, P.; Uuskula, M. (1994). Human glutathione-s-transferase gstm1 genetic-polymorphism in Estonia. Human Heredity, 44 (5), 248−251.
18.04.2019
Detailne otsing
  • Leitud 7 kirjet
ProgrammLiikNumberNimiProjekti algusProjekti lõppVastutav täitjaAsutusFinantseerijapoolne rahastamine
ETFETF7053Alkoholismi geneetika01.01.200731.12.2012Aavo LangTartu Ülikool, Arstiteaduskond45 096,06 EUR
ETFETF9262Epigeneetiliste modifitseerijate toime kokaiini poolt esilekutsutud käitumusliku sensitisatsiooni pööratavusele01.01.201231.12.2015Anti KaldaTartu Ülikool, Arstiteaduskond86 400,00 EUR
SFSF0182560s03Geneetilised ja rakulised haiguste põhjused, rakkude diferentseerumine ja tüvirakud teraapias01.01.200331.12.2007Aavo-Valdur MikelsaarTartu Ülikool, Arstiteaduskond477 675,66 EUR
SFSF0180096s08Inimese fetaalsete neuraalsete ja embrüonaalsete tüvirakkude differentseerumine neuraalses suunas ja uute immuunmarkerite loomine01.01.200831.12.2013Erkki JuronenTartu Ülikool, Arstiteaduskond483 282,82 EUR
ETFETF6589Inimgenoomi DNA järjestuste koopiaarvu varieeruvus ja genoomsed haigused01.01.200631.12.2009Gunnar TasaTartu Ülikool, Arstiteaduskond46 307,83 EUR
MUUSARMP13001T (3.2.0701.12-0049)Interleukiinid psoriaasi diagnostikas01.09.201231.08.2015Pärt PetersonTartu Ülikool289 975,00 EUR
ETFETF8981Membraaniga seotud mutsiinid kui kasvajate immuunoteraapia ja diagnostika sihtmolekulid.01.01.201231.12.2015Erkki JuronenTartu Ülikool, Arstiteaduskond96 000,00 EUR