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Harold Snieder

https://www.etis.ee/CV/Harold_Snieder/est
30.05.1965
h.snieder@med.umcg.nl

Teenistuskäik

Töökohad ja ametid
01.05.2010–...   
Tartu Ülikool, Tartu Ülikooli Eesti Geenivaramu, Professor (0,20)
01.01.2006–...   
Department of Epidemiology, University Medical Center Groningen, The Netherlands, Professor of Genetic Epidemiology
01.01.2006–...   
Medical College of Georgia, USA, Adjunct Professor of Pediatrics
01.01.2000–...   
King’s College, Twin Research & Genetic Epidemiology Unit, St Thomas’ Hospital, London, UK, Honorary Research Fellow
01.01.2005–31.12.2006   
Dept. of Biostatistics, Medical College of Georgia, USA, Full Professor of Pediatrics
01.01.2000–31.12.2005   
Medical College of Georgia, USA, Associate Professor of Pediatrics
01.01.1996–31.12.2000   
Twin Research & Genetic Epidemiology Unit, St Thomas’ Hospital, London, UK, Genetic Statistician & Honorary Lecturer
 
 
Haridustee
1991–1996   
PhD student, Vrije Universiteit, Amsterdam, The Netherlands
 
 
Teadusorganisatsiooniline ja -administratiivne tegevus
2010−...   
LifeLines coordinator of genetic studies & chair of GWAS committee. University Medical Center Groningen
2010−...   
Member of advisory committee to the Netherlands Heart Foundation on “Stress and Cardiovascular Disease”
2010−...   
Faculty member of Faculty of 1000 for Public Health & Epidemiology
2007−...   
Co-organiser (with Cisca Wijmenga and Marten Hofker) of Groningen Genetics Seminar Series
2006−...   
Member of National Academy of Sciences-National Research Council WWII Veteran Twin Registry Committee, Washington DC, USA
2000−...   
Member of International Genetic Epidemiology Society
1998−...   
Member of International Society for Twin Studies
1992−...   
Member of Behavior Genetic Association
1987−...   
Member of Dutch Association of Exercise Physiology
2012−2012   
Organized farewell symposium of dr. Peter Terpstra at the UMCG:“Sequencing: Past, present and the next-generation”.
2012−2012   
Member of scientific steering committee for The 14th Congress of the International Society of Twin Studies (ISTS), Florence, Italy
2010−2010   
Session organizer “Twin Registries in China” at the International Society of Twin Research Annual Meeting in Seoul, South Korea
2008−2008   
Invited participant of expert meeting organized by RIVM on ‘The genetics of overweight: societal consequences and policy implications.’
2008−2008   
Invited participant and speaker at expert meeting Netherlands Heart Foundation: ‘The stress-mechanism. The missing link.’
2008−2008   
Session chair WEON meeting: ‘Methods and design of Genetic Epidemiological Research.’
2005−2005   
Co-organiser (with Frank Treiber and Gerald McClearn) of NIH-NHLBI expert meeting on “Behavior Genetics and Cardiovascular Disease”.
2004−2004   
Co-organiser of the Pre-conference workshop of the 62nd Annual Meeting of the American Psychosomatic Society, Orlando FA: “Genetic epidemiology of Psychosomatic Disorders”
2004−2004   
Co-organiser of the Pre-conference workshop of the 44th Annual Meeting of the Society for Psychophysiological Research, Santa Fe NM: “Genetic Research in the Psychophysiological Laboratory”
2004−2004   
On student award committee for best poster and oral presentation of the 11th International Congress on Twin Studies, Odense, Denmark
2002−2003   
Appointed to the Postdoc Advisory Council, Medical College of Georgia
2001−2001   
Session organiser with Tim Spector: ‘Advances in twin and sib-pair study methodology’ at the 10th international congress on twin studies, 4-7 July 2001, London
2001−2003   
Member of committee investigating feasibility of Joint School of Public Health, Medical College of Georgia
2001−2002   
Member of search committee for endowed chair in Genomic Medicine, Medical College of Georgia
2001−2002   
Headed search for 2 tenure track faculty positions within Georgia Prevention Institute
2000−2000   
Organisation of “The second International Meeting on the Genetic Epidemiology of Complex Traits’, Churchill College, Cambridge, UK
1998−1998   
Organisation of “The first International Meeting on the Genetic Epidemiology of Complex Traits’, St. Catharines College, Cambridge, UK
1992−1993   
Member of the organizing committee of the annual meeting of the Dutch Association of Exercise Physiology

Kvalifikatsioon

Teaduskraadid
Harold Snieder, doktorikraad, 1996, (juh) J.F. Orlebeke, Genetic epidemiology of risk factors for coronary heart disease. A study of middle-aged twins, Vrije Universiteit.
 
 
Teaduspreemiad ja tunnustused
2002, Harold Snieder, David Fulker Award (together with Edwin van den Oord) for the best publication in Behavior Genetics in the year 2002

Lõppenud projektid

Juhendatud väitekirjad

Publikatsioonid

Klass
Aasta
Publikatsioon
 
1.1.
2015
Zhu, Z; Bakshi, A; Vinkhuyzen, AA; Hemani, G; Lee, SH; Nolte, IM; van, Vliet-Ostaptchouk, JV; Snieder, H; The, LifeLines, Cohort, Study; Esko, T; Milani, L; Mägi, R; Metspalu, A; Hill, WG; Weir, BS; Goddard, ME; Visscher, PM; Yang, J. (2015). Dominance Genetic Variation Contributes Little to the Missing Heritability for Human Complex Traits. American Journal of Human Genetics, 96 (3), 377−85.10.1016/j.ajhg.2015.01.001.
1.1.
2015
The, Coffee, and, Caffeine, Genetics, Consortium; Cornelis, MC; Byrne, EM; Esko, T; Nalls, MA; Ganna, A; Paynter, N; Monda, KL; Amin, N; Fischer, K; Renstrom, F; Ngwa, JS; Huikari, V; Cavadino, A; Nolte, IM; Teumer, A; Yu, K; Marques-Vidal, P; Rawal, R; Manichaikul, A ... Chasman, DI. (2015). Genome-wide meta-analysis identifies six novel loci associated with habitual coffee consumption. Molecular Psychiatry, 20 (5), 647−656.10.1038/mp.2014.107.
1.1.
2014
Simino, J.; Shi, G.; Bis, JC.; Chasman, DI.; Ehret, GB.; Gu, X.; Guo, X.; Hwang, SJ.; Sijbrands, E.; Smith, AV.; Verwoert, GC.; Bragg-Gresham, JL.; Cadby, G.; Chen, P.; Cheng, CY.; Corre, T.; de Boer, RA.; Goel, A.; Johnson, T.; Khor, CC. ... Rao, DC. (2014). Gene-Age Interactions in Blood Pressure Regulation: A Large-Scale Investigation with the CHARGE, Global BPgen, and ICBP Consortia. American Journal of Human Genetics, 95 (1), 24−38.10.1016/j.ajhg.2014.05.010.
1.1.
2013
Randall, JC; Winkler, TW; Kutalik, Z; Berndt, SI; Jackson, AU; Monda, KL; Kilpeläinen, TO; Esko, T; Mägi, R; Li, S; Workalemahu, T; Feitosa, MF; Croteau-Chonka, DC; Day, FR; Fall, T; Ferreira, T; Gustafsson, S; Locke, AE; Mathieson, I; Scherag, A ... Heid, IM (2013). Sex-stratified Genome-wide Association Studies Including 270,000 Individuals Show Sexual Dimorphism in Genetic Loci for Anthropometric Traits. PLOS Genetics, 9 (6), e1003500.10.1371/journal.pgen.1003500.
1.1.
2012
Nürnberg, ST.; Rendon, A.; Smethurst, PA.; Paul, DS.; Voss, K.; Thon, JN.; Lloyd-Jones, H.; Sambrook, JG.; Tijssen, MR.; Gieger, C.; Radhakrishnan, A.; Cvejic, A.; Tang, W.; Porcu, E.; Pistis, G.; Serbanovic-Canic, J.; Elling, U.; Goodall, AH.; Labrune, Y.; Lopez, LM. ... Ouwehand, W. (2012). A GWAS sequence variant for platelet volume marks an alternative DNM3 promoter in megakaryocytes near a MEIS1 binding site. Blood, 120 (24), 4859−4868.10.1182/blood-2012-01-401893.
1.1.
2012
Okada, Y; Sim, X; Go, MJ; Wu, JY; Gu, D; Takeuchi, F; Takahashi, A; Maeda, S; Tsunoda, T; Chen, P; Lim, SC; Wong, TY; Liu, J; Young, TL; Aung, T; Seielstad, M; Teo, YY; Kim, YJ; Lee, JY; Han, BG ... Gieger, C. (2012). Meta-analysis identifies multiple loci associated with kidney function-related traits in east Asian populations. Nature Genetics, 44 (8), 904−909.10.1038/ng.2352.
1.1.
2012
Stolk, L.; Perry, JR.; Chasman, DI.; He, C.; Mangino, M.; Sulem, P.; Barbalic, M.; Broer, L.; Byrne, EM.; Ernst, F.; Esko, T.; Franceschini, N.; Gudbjartsson, DF.; Hottenga, JJ.; Kraft, P.; McArdle, PF.; Porcu, E.; Shin, SY.; Smith, AV.; van Wingerden, S. ... Lunetta, KL. (2012). Meta-analyses identify 13 loci associated with age at menopause and highlight DNA repair and immune pathways. Nature Genetics, 44 (3), 260−268.10.1038/ng.1051.
1.1.
2011
Zhu, H; Wang, X; Gutin, B; Davis, CL; Keeton, D; Thomas, J; Stallmann-Jorgensen, I; Mooken, G; Bundy, V; Snieder, H; van der Harst, P; Dong, Y. (2011). Leukocyte telomere length in healthy Caucasian and African-American adolescents: relationships with race, sex, adiposity, adipokines, and physical activity. The Journal of Pediatrics, 158 (2), 2015−220.
1.1.
2011
Lagou, V; Liu, G; Zhu, H; Stallmann-Jorgensen, IS; Gutin, B; Dong, Y; Snieder, H. (2011). Lifestyle and socioeconomic-status modify the effects of ADRB2 and NOS3 on adiposity in European-American and African-American adolescents. Obesity, 19 (3), 595−603.
1.1.
2011
Wu, T; Snieder, H; Li, L; Cao, W; Zhan, S; Lv, J; Gao, W; Wang, X; Ding, X; Hu, Y. (2011). Genetic and environmental influences on blood pressure and body mass index in Han Chinese: a twin study. Hypertension Research, 34 (2), 173−179.
1.1.
2011
Wang, X; Ding, X; Su, S; Harshfield, G; Treiber, F; Snieder, H. (2011). Genetic influence on blood pressure measured in the office, under laboratory stress and during real life. Hypertension Research, 239−244.
1.1.
2011
Dehghan, A; … Snieder, H; .. Perola, M; Chasman, DI. (2011). Meta-analysis of genome-wide association studies in >80 000 subjects identifies multiple loci for C-reactive protein levels. Circulation, 123 (7), 731−738.
1.1.
2011
Vehof, J; Risselada, AJ; Al Hadithy, AF; Burger, H; Snieder, H; Wilffert, B; Arends, J; Wunderink, L; Knegtering, H; Wiersma, D; Cohen, D; Mulder, H; Bruggeman, R. (2011). Association of genetic variants of the histamine H1 and muscarinic M3 receptors with BMI and HbA1c values in patients on antipsychotic medication. Psychopharmacology, 216 (2), 257−265.10.1007/s00213-011-2211-x.
1.1.
2011
Vehof, J; Al Hadithy, AF; Burger, H; Snieder, H; Risselada, AJ; Wilffert, B; Cohen, D; Arends, J; Wiersma, D; Mulder, H; Bruggeman, R. (2011). Association between the ROBO1 gene and body mass index in patients using antipsychotics. Psychiatric Genetics, 21 (4), 202−207.10.1097/YPG.0b013e3283458a51.
1.1.
2011
Liu, G; Zhu, H; Dong, Y; Podolsky, RH; Treiber, FA; Snieder, H. (2011). Influence of common variants in FTO and near INSIG2 and MC4R on growth curves for adiposity in Africanand European-American youth. European Journal of Epidemiology, 26 (6), 463−473.10.1007/s10654-011-9583-4.
1.1.
2011
Hassan, MO; Jaju, D; Voruganti, VS; Bayoumi, RA; Albarwani, S; Al-Yahyaee, S; Aslani, A; Snieder, H; Lopez-Alvarenga, JC; Al-Anqoudi, ZM; Alizadeh, BZ; Comuzzie, AG. (2011). Genomewide linkage analysis of hemodynamic parameters under mental and physical stress in extended Omani Arab pedigrees: the Oman Family Study. Twin Research and Human Genetics, 14 (3), 257−267.1832-4274.
1.1.
2011
Gieger, C; Radhakrishnan, A; Cvejic, A; Tang, WH; Porcu, E; Pistis, G; Serbanovic-Canic, J; Elling, U; Goodall, AH; Labrune, Y; Lopez, LM; Magi, R; Meacham, S; Okada, Y; Pirastu, N; Sorice, R; Teumer, A; Voss, K; Zhang, WH; Ramirez-Solis, R ... Soranzo, N (2011). New gene functions in megakaryopoiesis and platelet formation. Nature, 480 (7376), 201−208.
1.1.
2011
Wang, Xiaoling; Prins, Bram P.; Sõber, Siim; Laan, Maris; Snieder, Harold (2011). Beyond Genome-Wide Association Studies: New Strategies for Identifying Genetic Determinants of Hypertension. Current Hypertension Reports, 13 (6), 442−451.DOI10.1007/s11906-011-0230-y.
1.1.
2011
The International Consortium for Blood Pressure Genome-Wide Association Studies, incl. Sõber, S.; Snieder, H.; Org, E.; Veldre, G.; Viigimaa, M.; Laan, M. (2011). Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk. Nature, 478 (7367), 103−109.10.1038/nature10405.
1.1.
2011
Wain, L.V.; Verwoert, G.C.; O'Reilly, P.F.; Shi, G.; Johnson, T.; Johnson, A.D.; Bochud, M.; Rice, K.M.; Henneman, P.; Smith, A.V.; Ehret, G.B.; Amin, N.; Larson, M.G.; Mooser, V.; Hadley, D.; Dörr, M.; Bis, J.C.; Aspelund, T.; Esko, T.; Janssens, A.C. ... Metspalu, A. et al (2011). Genome-wide association study identifies six new loci influencing pulse pressure and mean arterial pressure. Nature Genetics, 43, 1005−1011.10.1038/ng.922.
1.1.
2010
Liu, G; Zhu, H; Lagou, V; Gutin, B; Barbeau, P; Treiber, FA; Dong, Y; Snieder, H. (2010). Common variants near melanocortin 4 receptor are associated with general and visceral adiposity in European- and African-American youth. The Journal of Pediatrics, 156 (4), 598−605.
1.1.
2010
Li, Z; Snieder, H; Su, S; Harshfield, GA; Treiber, FA; Wang, X. (2010). A longitudinal study of blood pressure variability in African-American and European American youth. Journal of Hypertension, 28 (4), 715−722.
1.1.
2010
Su, S; Lampert, R; Lee, F; Bremner, JD; Snieder, H; Jones, L; Murrah, NV; Goldberg, J; Vaccarino, V. (2010). Common genes contribute to depressive symptoms and heart rate variability: the Twins Heart Study. Twin Research and Human Genetics, 1, 1−9.
1.1.
2010
Lee, J; Chen, L; Snieder, H; Chen, da F; Lee, LM; Liu, GF; Wu, T; Tang, X; Zhan, SY; Cao, WH; Lv, J; Gao, WJ; Hu, YH. (2010). Heritability of obesity-related phenotypes and association with adiponectin gene polymorphisms in the Chinese national twin registry. Annals of Human Genetics, 74 (2), 146−154.
1.1.
2010
Liu, G; Zhu, H; Lagou, V; Gutin, B; Stallmann-Jorgensen, IS; Treiber, FA; Dong, Y; Snieder, H. (2010). FTO variant rs9939609 is associated with body mass index and waist circumference, but not with energy intake or physical activity in European- and African-American youth. BMC Medical Genetics, 11, 57.10.1186/1471-2350-11-57.
1.1.
2010
Chambers, JC; ... Snieder, H; ... Kooner, JS. (2010). Genetic loci influencing kidney function and chronic kidney disease. Nature Genetics, 42 (5), 373−375.
1.1.
2010
Jamshidi, Y; Nolte, IM; Spector, TD; Snieder, H. (2010). Novel genes for QTc interval. How much heritability is explained, and how much is left to find? Genome Medicine, 2 (5), 35.10.1186/gm156.
1.1.
2010
Eijgelsheim, M; ... Snieder, H; ... O'Donnell, CJ. (2010). Genome-wide association analysis identifies multiple loci related to resting heart rate. Human Molecular Genetics, 19 (19), 3885−3894.
1.1.
2010
Wang, X; Snieder, H. (2010). Genome-wide association studies and beyond: what's next in blood pressure genetics? Hypertension, 56 (6), 1035−1037.
1.1.
2010
Sotoodehnia, N; ... Snieder, H (2010). Common variants in 22 loci are associated with QRS duration and cardiac ventricular conduction. Nature Genetics, 42 (12), 3885−3894.
1.1.
2010
Padmanabhan, S.; Melander, O.; Johnson, T.; Di Blasio, A. M.; Lee, W. K.; Gentilini, D.; Hastie, C. E.; Menni, C.; Monti, M. C.; Delles, C.; Laing, S.; Corso, B.; Navis, G.; Kwakernaak, A. J.; van der Harst, P.; Bochud, M.; Maillard, M.; Burnier, M.; Hedner, T.; Kjeldsen, S. ... Dominiczak, A. F. (2010). Genome-Wide Association Study of Blood Pressure Extremes Identifies Variant near UMOD Associated with Hypertension. PLOS Genetics, 6, e1001177.10.1371/journal.pgen.1001177.
1.1.
2009
Newton-Cheh, C.; Johnson, T.; Gateva, V.; Tobin, M.D.; Bochud, M.; Coin, L.; Najjar, S.S.; Zhao, J.H.; Heath, S.C.; Eyheramendy, S.; Papadakis, K.; Voight, B.F.; Scott, L.J.; Zhang, F.; Farrall, M.; Tanaka, T.; Wallace, C.; Chambers, J.C.; Khaw, K.T.; Nilsson, P. ... Wa (2009). Genome-wide association study identifies eight loci associated with blood pressure. Nature Genetics, 41, 666−676.10.1038/ng.361.
4.03.2020

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Uus Frascati (2015)
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ProgrammLiikNumberNimiProjekti algusProjekti lõppVastutav täitjaAsutusFinantseerijapoolne rahastamine
IUTIUT20-60Oomiksi põhised meetodid terviseuuringutes: integreeritud lähenemine haiguste tekkeprotsesside mõistmiseks ja prognoosimiseks01.01.201431.12.2019Andres MetspaluTartu Ülikool, Tartu Ülikooli Eesti Geenivaramu; Tartu Ülikool, Tartu Ülikooli genoomika instituut1 327 800,00 EUR