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Hindrek Teder

https://www.etis.ee/CV/Hindrek_Teder/eng
19.01.1989
hindrek.teder@ut.ee
E-7807-2017

Career

Institutions and positions
2016–...   
Competence Centre on Health Technologies, Bioinformatics Researcher (0,75)
2015–2016   
Competence Centre on Health Technologies, Bioinformatics Specialist (0,50)
2014–2015   
Competence Centre on Health Technologies, Laboratory Specialist (0,20)
 
 
Education
2016–...   
Doctoral studies in University of Tartu, Faculty of Medicine, Institute of Biomedicine and Translational Medicine, Medicine (Bioinformatics)
2013–2016   
Master's studies in University of Tartu, Faculty of Science and Technology, Institute of Molecular and Cell Biology, Genetic Engineering (Bioinformatics)
2008–2013   
Bachelor's studies in University of Tartu, Faculty of Science and Technology, Institute of Molecular and Cell Biology, Genetic Engineering
 
 
R&D related managerial and administrative work
2013−2016   
Bioscience Students’ Association

Qualifications

Academic degrees
Hindrek Teder, Master's Degree, 2016, (sup) Kaarel Krjutškov; Ants Kurg, Evaluation of the possibility to detect fetal chromosome trisomies based on a defined set of single nucleotide polymorphisms for non-invasive prenatal testing, University of Tartu, Faculty of Science and Technology, Institute of Molecular and Cell Biology.
Hindrek Teder, PhD student, (sup) Priit Palta; Kaarel Krjutškov; Andres Salumets, Development of analytical pipeline for fully quantitative TAC-seq method in clinical molecular diagnostics, University of Tartu, Faculty of Medicine, Institute of Clinical Medicine
 
 
Fields of research
ETIS CLASSIFICATION: 3. Health; 3.11. Biochemistry, Genetics, Microbiology, Biotechnology, Molecular Biology, Cell Biology, Biophysics and Bioinformatics relating to Health Studies; CERCS CLASSIFICATION: B110 Bioinformatics, medical informatics, biomathematics, biometrics
 
 

Projects in progress

Publications

Category
Year
Publication
 
1.1.
2021
Paluoja, Priit; Teder, Hindrek; Ardeshirdavani, Amin; Bayindir, Baran; Vermeesch, Joris; Salumets, Andres; Krjutškov, Kaarel; Palta, Priit (2021). Systematic evaluation of NIPT aneuploidy detection software tools with clinically validated NIPT samples. PLoS Computational Biology, 17 (12), e1009684. DOI: 10.1371/journal.pcbi.1009684.
1.1.
2020
Wedenoja, Satu; Yoshihara, Masahito; Teder, Hindrek; Sariola, Hannu; Gissler, Mika; Katayama, Shintaro; Wedenoja, Juho; Häkkinen, Inka M; Ezer, Sini; Linder, Nina; Lundin, Johan; Skoog, Tiina; Sahlin, Ellika; Iwarsson, Erik; Pettersson, Karin; Kajantie, Eero; Mokkonen, Mikael; Heinonen, Seppo; Laivuori, Hannele; Krjutškov, Kaarel ... Kere, Juha (2020). Fetal HLA-G mediated immune tolerance and interferon response in preeclampsia. EBioMedicine, 102872−102872. DOI: 10.1016/j.ebiom.2020.102872.
1.1.
2019
Teder, Hindrek; Paluoja, Priit; Rekker, Kadri; Salumets, Andres; Krjutskov, Kaarel; Palta, Priit (2019). Computational framework for targeted high coverage sequencing based NIPT Computational framework for targeted high coverage sequencing based NIPT. PLoS ONE, 14 (7), ARTN e0209139. DOI: 10.1371/journal.pone.0209139.
1.1.
2019
Žilina, Olga; Rekker, Kadri; Kaplinski, Lauris; Sauk, Martin; Paluoja, Priit; Teder, Hindrek; Ustav, Eva-Liina; Tõnisson, Neeme; Reimand, Tiia; Ridnoi, Konstantin; Palta, Priit; Vermeesch, Joris Robert; Krjutškov, Kaarel; Kurg, Ants; Salumets, Andres (2019). Creating basis for introducing non-invasive prenatal testing in the Estonian public health setting. Prenatal Diagnosis, 39 (13), 1262−1268. DOI: 10.1002/pd.5578.
6.8.
2019
Saare, Merli; Laisk, Triin; Teder, Hindrek; Paluoja, Priit; Palta, Priit; Koel, Mariann; Kirss, Fred; Karro, Helle; Soritsa, Deniss; Salumets, Andres; Krjutškov, Kaarel; Peters, Maire (2019). A molecular tool for menstrual cycle phase dating of endometrial samples in endometriosis transcriptome studies. Biology of Reproduction, 101 (1), 1−3. DOI: 10.1093/biolre/ioz072.
1.1.
2018
Teder, Hindrek; Koel, Mariann; Paluoja, Priit; Jatsenko, Tatjana; Rekker, Kadri; Laisk-Podar, Triin; Kukuškina, Viktorija; Velthut-Meikas, Agne; Fjodorova, Olga; Peters, Maire; Kere, Juha; Salumets, Andres; Palta, Priit; Krjutškov, Kaarel (2018). TAC-seq: targeted DNA and RNA sequencing for precise biomarker molecule counting. npj Genomic Medicine, 3, ARTN 34. DOI: 10.1038/s41525-018-0072-5.
1.1.
2018
Sauk, M.; Žilina, O.; Kurg, A.; Ustav, E-L.; Peters, M.; Paluoja, P.; Roost, A.M.; Teder, H.; Palta, P.; Brison, N.; Vermeesch, J.R.; Krjutškov, K.; Salumets, A; Kaplinski, L. (2018). NIPTmer: rapid k-mer-based software package for detection of fetal aneuploidies. Scientific Reports. DOI: 10.1038/s41598-018-23589-8.
1.1.
2018
Sõritsa, D.; Teder, H.; Roosipuu, R.; Tamm, H.; Laisk-Podar, T.; Soplepmann, P.; Altraja, A.; Salumets, A.; Peters, M. (2018). Whole exome sequencing of benign pulmonary metastasizing leiomyoma reveals mutation in the BMP8B gene. BMC Medical Genetics, 19 (1), 20. DOI: 10.1186/s12881-018-0537-5.
5.2.
2018
Rekker, K.; Fjodorova, O.; Teder, H.; Paluoja, P.; Palta, P.; Ustav, E-L.; Ridnõi, K.; Kurg, A.; Kaplinski, L.; Krjutškov, K.; Salumets, A. (2018). NIPT – suure tundlikkusega meetod loote kromosoomhaiguste varajaseks tuvastamiseks. Eesti Arst, 97(Lisa 2): Tartu Ülikooli arstiteaduskonna aastapäeva teaduskonverents 2018; Tartu; 11.-12. okt. 2018. OÜ Celsius Healthcare, 37.
1.1.
2016
Krjutškov, K; Katayama, S; Saare, M; Vera-Rodriguez, M; Lubenets, D; Samuel, K; Laisk-Podar, T; Teder, H; Einarsdottir, E; Salumets, A; Kere, J (2016). Single-cell transcriptome analysis of endometrial tissue. Human Reproduction, 31 (4), 844−853. DOI: 10.1093/humrep/dew008.
21.12.2021

Hindrek Teder

https://www.etis.ee/CV/Hindrek_Teder/est
19.01.1989
hindrek.teder@ut.ee
E-7807-2017

Teenistuskäik

Töökohad ja ametid
2016–...   
Tervisetehnoloogiate Arenduskeskus AS (endine Reproduktiivmeditsiini TAK AS) , Bioinformaatika teadur (0,75)
2015–2016   
Tervisetehnoloogiate Arenduskeskus AS (endine Reproduktiivmeditsiini TAK AS) , Bioinformaatika spetsialist (0,50)
2014–2015   
Tervisetehnoloogiate Arenduskeskus AS (endine Reproduktiivmeditsiini TAK AS) , Laborispetsialist (0,20)
 
 
Haridustee
2016–...   
Tartu Ülikool, meditsiiniteaduste valdkond, bio- ja siirdemeditsiini instituut, Arstiteaduse (Bioinformaatika) doktoriõpe
2013–2016   
Tartu Ülikool, loodus- ja täppisteaduste valdkond, molekulaar- ja rakubioloogia instituut, Geenitehnoloogia (Bioinformaatika) magistriõpe
2008–2013   
Tartu Ülikool, loodus- ja tehnoloogiateaduskond, molekulaar- ja rakubioloogia instituut, Geenitehnoloogia bakalaureuseõpe
2005–2008   
Rapla Ühisgümnaasium
1996–2005   
Valtu Põhikool
 
 
Teadusorganisatsiooniline ja -administratiivne tegevus
2013−2016   
Bioteaduste Üliõpilaste Selts

Kvalifikatsioon

Teaduskraadid
Hindrek Teder, Master's Degree, 2016, (sup) Kaarel Krjutškov; Ants Kurg, Evaluation of the possibility to detect fetal chromosome trisomies based on a defined set of single nucleotide polymorphisms for non-invasive prenatal testing, University of Tartu, Faculty of Science and Technology, Institute of Molecular and Cell Biology.
Hindrek Teder, PhD student, (sup) Priit Palta; Kaarel Krjutškov; Andres Salumets, Development of analytical pipeline for fully quantitative TAC-seq method in clinical molecular diagnostics, University of Tartu, Faculty of Medicine, Institute of Clinical Medicine
 
 
Teadustöö põhisuunad
ETIS KLASSIFIKAATOR: 3. Terviseuuringud; 3.11. Terviseuuringutega seotud uuringud, näiteks biokeemia, geneetika, mikrobioloogia, biotehnoloogia, molekulaarbioloogia, rakubioloogia, biofüüsika ja bioinformaatika; CERCS KLASSIFIKAATOR: B110 Bioinformaatika, meditsiiniinformaatika, biomatemaatika, biomeetrika

Jooksvad projektid

Publikatsioonid

Klass
Aasta
Publikatsioon
 
1.1.
2021
Paluoja, Priit; Teder, Hindrek; Ardeshirdavani, Amin; Bayindir, Baran; Vermeesch, Joris; Salumets, Andres; Krjutškov, Kaarel; Palta, Priit (2021). Systematic evaluation of NIPT aneuploidy detection software tools with clinically validated NIPT samples. PLoS Computational Biology, 17 (12), e1009684. DOI: 10.1371/journal.pcbi.1009684.
1.1.
2020
Wedenoja, Satu; Yoshihara, Masahito; Teder, Hindrek; Sariola, Hannu; Gissler, Mika; Katayama, Shintaro; Wedenoja, Juho; Häkkinen, Inka M; Ezer, Sini; Linder, Nina; Lundin, Johan; Skoog, Tiina; Sahlin, Ellika; Iwarsson, Erik; Pettersson, Karin; Kajantie, Eero; Mokkonen, Mikael; Heinonen, Seppo; Laivuori, Hannele; Krjutškov, Kaarel ... Kere, Juha (2020). Fetal HLA-G mediated immune tolerance and interferon response in preeclampsia. EBioMedicine, 102872−102872. DOI: 10.1016/j.ebiom.2020.102872.
1.1.
2019
Teder, Hindrek; Paluoja, Priit; Rekker, Kadri; Salumets, Andres; Krjutskov, Kaarel; Palta, Priit (2019). Computational framework for targeted high coverage sequencing based NIPT Computational framework for targeted high coverage sequencing based NIPT. PLoS ONE, 14 (7), ARTN e0209139. DOI: 10.1371/journal.pone.0209139.
1.1.
2019
Žilina, Olga; Rekker, Kadri; Kaplinski, Lauris; Sauk, Martin; Paluoja, Priit; Teder, Hindrek; Ustav, Eva-Liina; Tõnisson, Neeme; Reimand, Tiia; Ridnoi, Konstantin; Palta, Priit; Vermeesch, Joris Robert; Krjutškov, Kaarel; Kurg, Ants; Salumets, Andres (2019). Creating basis for introducing non-invasive prenatal testing in the Estonian public health setting. Prenatal Diagnosis, 39 (13), 1262−1268. DOI: 10.1002/pd.5578.
6.8.
2019
Saare, Merli; Laisk, Triin; Teder, Hindrek; Paluoja, Priit; Palta, Priit; Koel, Mariann; Kirss, Fred; Karro, Helle; Soritsa, Deniss; Salumets, Andres; Krjutškov, Kaarel; Peters, Maire (2019). A molecular tool for menstrual cycle phase dating of endometrial samples in endometriosis transcriptome studies. Biology of Reproduction, 101 (1), 1−3. DOI: 10.1093/biolre/ioz072.
1.1.
2018
Teder, Hindrek; Koel, Mariann; Paluoja, Priit; Jatsenko, Tatjana; Rekker, Kadri; Laisk-Podar, Triin; Kukuškina, Viktorija; Velthut-Meikas, Agne; Fjodorova, Olga; Peters, Maire; Kere, Juha; Salumets, Andres; Palta, Priit; Krjutškov, Kaarel (2018). TAC-seq: targeted DNA and RNA sequencing for precise biomarker molecule counting. npj Genomic Medicine, 3, ARTN 34. DOI: 10.1038/s41525-018-0072-5.
1.1.
2018
Sauk, M.; Žilina, O.; Kurg, A.; Ustav, E-L.; Peters, M.; Paluoja, P.; Roost, A.M.; Teder, H.; Palta, P.; Brison, N.; Vermeesch, J.R.; Krjutškov, K.; Salumets, A; Kaplinski, L. (2018). NIPTmer: rapid k-mer-based software package for detection of fetal aneuploidies. Scientific Reports. DOI: 10.1038/s41598-018-23589-8.
1.1.
2018
Sõritsa, D.; Teder, H.; Roosipuu, R.; Tamm, H.; Laisk-Podar, T.; Soplepmann, P.; Altraja, A.; Salumets, A.; Peters, M. (2018). Whole exome sequencing of benign pulmonary metastasizing leiomyoma reveals mutation in the BMP8B gene. BMC Medical Genetics, 19 (1), 20. DOI: 10.1186/s12881-018-0537-5.
5.2.
2018
Rekker, K.; Fjodorova, O.; Teder, H.; Paluoja, P.; Palta, P.; Ustav, E-L.; Ridnõi, K.; Kurg, A.; Kaplinski, L.; Krjutškov, K.; Salumets, A. (2018). NIPT – suure tundlikkusega meetod loote kromosoomhaiguste varajaseks tuvastamiseks. Eesti Arst, 97(Lisa 2): Tartu Ülikooli arstiteaduskonna aastapäeva teaduskonverents 2018; Tartu; 11.-12. okt. 2018. OÜ Celsius Healthcare, 37.
1.1.
2016
Krjutškov, K; Katayama, S; Saare, M; Vera-Rodriguez, M; Lubenets, D; Samuel, K; Laisk-Podar, T; Teder, H; Einarsdottir, E; Salumets, A; Kere, J (2016). Single-cell transcriptome analysis of endometrial tissue. Human Reproduction, 31 (4), 844−853. DOI: 10.1093/humrep/dew008.
21.12.2021

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ProgramTypeNumberNameProject startProject endPrincipal investigatorInstitutionFinancing
MUUEU48695Competence Centre on Health Technologies01.09.201531.08.2022Andres SalumetsCompetence Centre on Health Technologies6 916 472,93 EUR
PRGPRG1076The role of endometrium as a major factor affecting female fertility and pregnancy outcome01.01.202131.12.2025Helle KarroUniversity of Tartu, Faculty of Medicine, Institute of Clinical Medicine366 500,00 EUR