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Iuriy Ermolovich

https://www.etis.ee/CV/Iuriy_Ermolovich/est
19.08.1988
+37258476176
iuriy.ermolovich@ttu.ee

Teenistuskäik

Töökohad ja ametid
01.10.2016–31.01.2018   
Tallinna Tehnikaülikool, Loodusteaduskond, Keemia ja biotehnoloogia instituut, Teadur (1,00)
01.11.2015–30.09.2016   
Institute of Bioorganic Chemistry, National Academy of Sciences of Belarus, Vanemteadur (1,00)
17.11.2013–30.10.2015   
Institute of Bioorganic Chemistry, National Academy of Sciences of Belarus, Teadur (1,00)
01.07.2010–16.11.2010   
Institute of Bioorganic Chemistry, National Academy of Sciences of Belarus, Nooremteadur (1,00)
 
 
Haridustee
2010–2013   
PhD in Organic Chemistry, National Academy of Sciences of Belarus
2005–2010   
Specialist in Chemistry (“Chemist. Researcher”), Belarusian State University, Faculty of Chemistry

Kvalifikatsioon

Teaduskraadid
Iuriy Ermolovich, doktorikraad, 2015, (juh) D.Sc. Vladimir Zhabinskii, Формирование боковой цепи стероидов с использованием сигматропных перегруппировок, Institute of Bioorganic Chemistry, National Academy of Sciences of Belarus.
 
 
Teaduspreemiad ja tunnustused
2016, Iuriy Ermolovich, Best Ph.D. thesis award (natural sciences), Higher Attestation Commission of Belarus
2015, Iuriy Ermolovich, 1. Scholarship of the President of the Republic of Belarus for postgraduate students (awarded for high academic standing and excellence in research).
 
 
Teadustöö põhisuunad
ETIS KLASSIFIKAATOR: 4. Loodusteadused ja tehnika; 4.11. Keemia ja keemiatehnika; CERCS KLASSIFIKAATOR: P390 Orgaaniline keemia

Publikatsioonid

Klass
Aasta
Publikatsioon
 
1.1.
2019
Ermolovich, Y.; Barysevich, M. V.; Adamson, J.; Rogova, O.; Kaabel, S.; Järving, I.; Gathergood, N.; Snieckus, V.; Kananovich, D. G. (2019). Site-Selective and Stereoselective C–H Functionalization of N-Cyclopropylamides via a Directed Remote Metalation Strategy. Organic Letters. DOI: 10.1021/acs.orglett.8b03955.
5.2.
2017
Ermolovich, Y.; Kananovich, D. (2017). Remote functionalization of donor-substituted cyclopropanes via directed metalation strategy. Book of Abstracts: 20th European Symposium on Organic Chemistry, Cologne, Germany, July 2-6, 2017. University of Cologne.
5.2.
2017
Ermolovich, Y. V.; Gathergood, N.; Kananovich, D. G. (2017). Directed metalation-based approach towards diastereoselective functionalization of cyclopropanes. Book of Abstracts: 18th Tetrahedron Symposium: New Developments in Organic Chemistry. Budapest, Hungary, 27-30 June 2017. Elsevier.
1.1.
2015
Alshakova, Irina D; Ermolovich, Yuri V; Zhabinskii, Vladimir N; Khripach, Vladimir A (2015). A new synthesis of brassinosteroids with a cholestane framework based on a highly functionalized starting material. Steroids, 97, 72−77.10.1016/j.steroids.2014.08.020.
1.1.
2015
Malachowska-Ugarte, Magdalena; Sperduto, Claudio; Ermolovich, Yuri V; Sauchuk, Alina L; Jurášek, Michal; Litvinovskaya, Raisa P; Straltsova, Darya; Smolich, Igor; Zhabinskii, Vladimir N; Drašar, Pavel; Demidchik, Vadim; Khripach, Vladimir A (2015). Brassinosteroid-BODIPY conjugates: Design, synthesis, and properties. Steroids, 102, 53−59.10.1016/j.steroids.2015.07.002.
1.1.
2015
Ermolovich, Yu. V.; Zhabinskii, V. N.; Khripach, V. A. (2015). Formation of the steroidal C-25 chiral center via the asymmetric alkylation methodology. Organic & Biomolecular Chemistry, 13 (3), 776−782. DOI: 10.1039/c4ob02123a.
1.1.
2015
Hurski, A L; Ermolovich, Yu V; Zhabinskii, V N; Khripach, V A (2015). The development and use of a general route to brassinolide, its biosynthetic precursors, metabolites and analogues. Organic & Biomolecular Chemistry, 13 (5), 1446−1452.10.1039/c4ob02197e.
3.1.
2015
Khripach, Vladimir A.; Zhabinskii, Vladimir N.; Ermolovich, Yuri V.; (2015). Chapter 6 - Synthetic Aspects of Brassinosteroids. In: Atta-ur-Rahman (Ed.). Studies in Natural Products Chemistry (309−352). Elsevier. DOI: 10.1016/B978-0-444-63460-3.00006-7.
1.1.
2013
Ermolovich, Yurii V; Zhabinskii, Vladimir N; Khripach, Vladimir A (2013). 1,4-Chirality transfer via the ester enolate Claisen rearrangements in the preparation of (25R)- and (25S)-cholestenoic acids. Steroids, 78 (7), 683−692.10.1016/j.steroids.2013.03.006.
1.1.
2013
Khripach, Vladimir A.; Tarkowska, Danuse; Zhabinskii, Vladimir N.; Gulyakevich, Olga V.; Ermolovich, Yurii V.; Drasar, Pavel; Strnad, Miroslav (2013). Synthesis and Mass Spectral Fragmentation Patterns of Brassinolide Early Biosynthetic Precursors Labeled at C-26. Natural Product Communications, 6, 771−774.
1.1.
2012
Khripach, V. A.; Zhabinskii, V. N.; Ermolovich, Yu. V.; Gulyakevich, O. V.; Mekhtiev, A. R.; Karalkin, P. A. (2012). Synthesis and biological activity of the probable biosynthetic precursors of 24(1)-norbrassinolide. Russian Journal of Bioorganic Chemistry, 4, 438−446.10.1134/S1068162012040097.
1.1.
2012
Khripach, V. A.; Zhabinskii, V. N.; Ermolovich, Yu. V.; Gulyakevich, O. V. (2012). Synthesis of [26-H-2(3)]-campesterin and [26-H-2(3)]-campestanol, deuterated analogs of biosynthetic precursors of 28C-brassinosteroids. Chemistry of Natural Compounds, 4, 606−609. DOI: 10.1007/s10600-012-0323-0.
1.1.
2012
Khripach, V. A.; Zhabinskii, V. N.; Gulyakevich, O. V.; Ermolovich, Yu. V. (2012). Synthesis of [26-H-2(3)]-6-deoxo-24-epicastasterone. Chemistry of Natural Compounds, 4, 601−605. DOI: 10.1007/s10600-012-0322-1.
1.2.
2012
Khripach, V A; Zhabinskiĭ, V N; Ermolovich, Iu V; Guliakevich, O V; Mekhtiev, A R; Karalkin, P A (2012). [Synthesis and biological activity of probable 24-norbrassinolide biosynthetic precursors]. Bioorganicheskaya Khimiya, 38 (4), 499−508.
1.1.
2011
Khripach, Vladimir A.; Zhabinskii, Vladimir N.; Gulyakevich, Olga V.; Ermolovich, Yurii V.; Konstantinova, Olga V. (2011). Synthesis of deuterium-labeled (24R)-methyl brassinosteroids. Journal of Labelled Compounds and Radiopharmaceuticals, 6, 332−336. DOI: 10.1002/jlcr.1874.
1.1.
2010
Khripach, Vladimir A.; Zhabinskii, Vladimir N.; Ermolovich, Yurii V. (2010). Improved Synthesis of 28-Norbrassinolide. Synthetic Communications, 18, 2780−2787.10.1080/00397910903318757.

Tööstusomand

4.03.2020

Iuriy Ermolovich

https://www.etis.ee/CV/Iuriy_Ermolovich/eng
19.08.1988
+37258476176
iuriy.ermolovich@ttu.ee

Career

Institutions and positions
01.10.2016–31.01.2018   
Tallinn University of Technology , School of Science, Department of Chemistry and Biotechnology, Researcher (1,00)
01.11.2015–30.09.2016   
Institute of Bioorganic Chemistry, National Academy of Sciences of Belarus, Senior Researcher (1,00)
17.11.2013–30.10.2015   
Institute of Bioorganic Chemistry, National Academy of Sciences of Belarus, Researcher (1,00)
01.07.2010–16.11.2010   
Institute of Bioorganic Chemistry, National Academy of Sciences of Belarus, Junior Researcher (1,00)
 
 
Education
2010–2013   
PhD in Organic Chemistry, National Academy of Sciences of Belarus
2005–2010   
Specialist in Chemistry (“Chemist. Researcher”), Belarusian State University, Faculty of Chemistry

Qualifications

Academic degrees
Iuriy Ermolovich, Doctor's Degree, 2015, (sup) D.Sc. Vladimir Zhabinskii, Формирование боковой цепи стероидов с использованием сигматропных перегруппировок (Formation of steroidal side chains via sigmatropic rearrangements), Institute of Bioorganic Chemistry, National Academy of Sciences of Belarus.
 
 
Honours & awards
2016, Iuriy Ermolovich, Best Ph.D. thesis award (natural sciences), Higher Attestation Commission of Belarus
2015, Iuriy Ermolovich, 1. Scholarship of the President of the Republic of Belarus for postgraduate students (awarded for high academic standing and excellence in research).
 
 
Fields of research
ETIS CLASSIFICATION: 4. Natural Sciences and Engineering; 4.11. Chemistry and Chemical Technology; CERCS CLASSIFICATION: P390 Organic chemistry

Publications

Category
Year
Publication
 
1.1.
2019
Ermolovich, Y.; Barysevich, M. V.; Adamson, J.; Rogova, O.; Kaabel, S.; Järving, I.; Gathergood, N.; Snieckus, V.; Kananovich, D. G. (2019). Site-Selective and Stereoselective C–H Functionalization of N-Cyclopropylamides via a Directed Remote Metalation Strategy. Organic Letters. DOI: 10.1021/acs.orglett.8b03955.
5.2.
2017
Ermolovich, Y.; Kananovich, D. (2017). Remote functionalization of donor-substituted cyclopropanes via directed metalation strategy. Book of Abstracts: 20th European Symposium on Organic Chemistry, Cologne, Germany, July 2-6, 2017. University of Cologne.
5.2.
2017
Ermolovich, Y. V.; Gathergood, N.; Kananovich, D. G. (2017). Directed metalation-based approach towards diastereoselective functionalization of cyclopropanes. Book of Abstracts: 18th Tetrahedron Symposium: New Developments in Organic Chemistry. Budapest, Hungary, 27-30 June 2017. Elsevier.
1.1.
2015
Alshakova, Irina D; Ermolovich, Yuri V; Zhabinskii, Vladimir N; Khripach, Vladimir A (2015). A new synthesis of brassinosteroids with a cholestane framework based on a highly functionalized starting material. Steroids, 97, 72−77.10.1016/j.steroids.2014.08.020.
1.1.
2015
Malachowska-Ugarte, Magdalena; Sperduto, Claudio; Ermolovich, Yuri V; Sauchuk, Alina L; Jurášek, Michal; Litvinovskaya, Raisa P; Straltsova, Darya; Smolich, Igor; Zhabinskii, Vladimir N; Drašar, Pavel; Demidchik, Vadim; Khripach, Vladimir A (2015). Brassinosteroid-BODIPY conjugates: Design, synthesis, and properties. Steroids, 102, 53−59.10.1016/j.steroids.2015.07.002.
1.1.
2015
Ermolovich, Yu. V.; Zhabinskii, V. N.; Khripach, V. A. (2015). Formation of the steroidal C-25 chiral center via the asymmetric alkylation methodology. Organic & Biomolecular Chemistry, 13 (3), 776−782. DOI: 10.1039/c4ob02123a.
1.1.
2015
Hurski, A L; Ermolovich, Yu V; Zhabinskii, V N; Khripach, V A (2015). The development and use of a general route to brassinolide, its biosynthetic precursors, metabolites and analogues. Organic & Biomolecular Chemistry, 13 (5), 1446−1452.10.1039/c4ob02197e.
3.1.
2015
Khripach, Vladimir A.; Zhabinskii, Vladimir N.; Ermolovich, Yuri V.; (2015). Chapter 6 - Synthetic Aspects of Brassinosteroids. In: Atta-ur-Rahman (Ed.). Studies in Natural Products Chemistry (309−352). Elsevier. DOI: 10.1016/B978-0-444-63460-3.00006-7.
1.1.
2013
Ermolovich, Yurii V; Zhabinskii, Vladimir N; Khripach, Vladimir A (2013). 1,4-Chirality transfer via the ester enolate Claisen rearrangements in the preparation of (25R)- and (25S)-cholestenoic acids. Steroids, 78 (7), 683−692.10.1016/j.steroids.2013.03.006.
1.1.
2013
Khripach, Vladimir A.; Tarkowska, Danuse; Zhabinskii, Vladimir N.; Gulyakevich, Olga V.; Ermolovich, Yurii V.; Drasar, Pavel; Strnad, Miroslav (2013). Synthesis and Mass Spectral Fragmentation Patterns of Brassinolide Early Biosynthetic Precursors Labeled at C-26. Natural Product Communications, 6, 771−774.
1.1.
2012
Khripach, V. A.; Zhabinskii, V. N.; Ermolovich, Yu. V.; Gulyakevich, O. V.; Mekhtiev, A. R.; Karalkin, P. A. (2012). Synthesis and biological activity of the probable biosynthetic precursors of 24(1)-norbrassinolide. Russian Journal of Bioorganic Chemistry, 4, 438−446.10.1134/S1068162012040097.
1.1.
2012
Khripach, V. A.; Zhabinskii, V. N.; Ermolovich, Yu. V.; Gulyakevich, O. V. (2012). Synthesis of [26-H-2(3)]-campesterin and [26-H-2(3)]-campestanol, deuterated analogs of biosynthetic precursors of 28C-brassinosteroids. Chemistry of Natural Compounds, 4, 606−609. DOI: 10.1007/s10600-012-0323-0.
1.1.
2012
Khripach, V. A.; Zhabinskii, V. N.; Gulyakevich, O. V.; Ermolovich, Yu. V. (2012). Synthesis of [26-H-2(3)]-6-deoxo-24-epicastasterone. Chemistry of Natural Compounds, 4, 601−605. DOI: 10.1007/s10600-012-0322-1.
1.2.
2012
Khripach, V A; Zhabinskiĭ, V N; Ermolovich, Iu V; Guliakevich, O V; Mekhtiev, A R; Karalkin, P A (2012). [Synthesis and biological activity of probable 24-norbrassinolide biosynthetic precursors]. Bioorganicheskaya Khimiya, 38 (4), 499−508.
1.1.
2011
Khripach, Vladimir A.; Zhabinskii, Vladimir N.; Gulyakevich, Olga V.; Ermolovich, Yurii V.; Konstantinova, Olga V. (2011). Synthesis of deuterium-labeled (24R)-methyl brassinosteroids. Journal of Labelled Compounds and Radiopharmaceuticals, 6, 332−336. DOI: 10.1002/jlcr.1874.
1.1.
2010
Khripach, Vladimir A.; Zhabinskii, Vladimir N.; Ermolovich, Yurii V. (2010). Improved Synthesis of 28-Norbrassinolide. Synthetic Communications, 18, 2780−2787.10.1080/00397910903318757.

Industrial property

4.03.2020

Otsi publikatsiooni

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PublikatsioonAutoridAastaVäljaande pealkiriKlassifikaatorFailAsutused
Site-Selective and Stereoselective C–H Functionalization of N-Cyclopropylamides via a Directed Remote Metalation StrategyErmolovich, Y.; Barysevich, M. V.; Adamson, J.; Rogova, O.; Kaabel, S.; Järving, I.; Gathergood, N.; Snieckus, V.; Kananovich, D. G.2019Organic Letters1.1.Tallinna Tehnikaülikool, Loodusteaduskond, Keemia ja biotehnoloogia instituut
Directed metalation-based approach towards diastereoselective functionalization of cyclopropanesErmolovich, Y. V.; Gathergood, N.; Kananovich, D. G.2017Book of Abstracts5.2.Tallinna Tehnikaülikool, Loodusteaduskond, Keemia ja biotehnoloogia instituut
Remote functionalization of donor-substituted cyclopropanes via directed metalation strategyErmolovich, Y.; Kananovich, D.2017Book of Abstracts5.2.Tallinna Tehnikaülikool, Loodusteaduskond, Keemia ja biotehnoloogia instituut
A new synthesis of brassinosteroids with a cholestane framework based on a highly functionalized starting material.Alshakova, Irina D; Ermolovich, Yuri V; Zhabinskii, Vladimir N; Khripach, Vladimir A2015Steroids1.1.
Brassinosteroid-BODIPY conjugates: Design, synthesis, and properties.Malachowska-Ugarte, Magdalena; Sperduto, Claudio; Ermolovich, Yuri V; Sauchuk, Alina L; Jurášek, Michal; Litvinovskaya, Raisa P; Straltsova, Darya; Smolich, Igor; Zhabinskii, Vladimir N; Drašar, Pavel; Demidchik, Vadim; Khripach, Vladimir A2015Steroids1.1.
Formation of the steroidal C-25 chiral center via the asymmetric alkylation methodologyErmolovich, Yu. V.; Zhabinskii, V. N.; Khripach, V. A.2015Organic & Biomolecular Chemistry1.1.
The development and use of a general route to brassinolide, its biosynthetic precursors, metabolites and analogues.Hurski, A L; Ermolovich, Yu V; Zhabinskii, V N; Khripach, V A2015Organic & Biomolecular Chemistry1.1.
Chapter 6 - Synthetic Aspects of BrassinosteroidsKhripach, Vladimir A.; Zhabinskii, Vladimir N.; Ermolovich, Yuri V.;2015Studies in Natural Products Chemistry3.1.
1,4-Chirality transfer via the ester enolate Claisen rearrangements in the preparation of (25R)- and (25S)-cholestenoic acids.Ermolovich, Yurii V; Zhabinskii, Vladimir N; Khripach, Vladimir A2013Steroids1.1.
Synthesis and Mass Spectral Fragmentation Patterns of Brassinolide Early Biosynthetic Precursors Labeled at C-26Khripach, Vladimir A.; Tarkowska, Danuse; Zhabinskii, Vladimir N.; Gulyakevich, Olga V.; Ermolovich, Yurii V.; Drasar, Pavel; Strnad, Miroslav2013Natural Product Communications1.1.
Synthesis and biological activity of the probable biosynthetic precursors of 24(1)-norbrassinolideKhripach, V. A.; Zhabinskii, V. N.; Ermolovich, Yu. V.; Gulyakevich, O. V.; Mekhtiev, A. R.; Karalkin, P. A.2012Russian Journal of Bioorganic Chemistry1.1.
Synthesis of [26-H-2(3)]-6-deoxo-24-epicastasteroneKhripach, V. A.; Zhabinskii, V. N.; Gulyakevich, O. V.; Ermolovich, Yu. V.2012Chemistry of Natural Compounds1.1.
Synthesis of [26-H-2(3)]-campesterin and [26-H-2(3)]-campestanol, deuterated analogs of biosynthetic precursors of 28C-brassinosteroidsKhripach, V. A.; Zhabinskii, V. N.; Ermolovich, Yu. V.; Gulyakevich, O. V.2012Chemistry of Natural Compounds1.1.
[Synthesis and biological activity of probable 24-norbrassinolide biosynthetic precursors].Khripach, V A; Zhabinskiĭ, V N; Ermolovich, Iu V; Guliakevich, O V; Mekhtiev, A R; Karalkin, P A2012Биоорганическая химия1.2.
Synthesis of deuterium-labeled (24R)-methyl brassinosteroidsKhripach, Vladimir A.; Zhabinskii, Vladimir N.; Gulyakevich, Olga V.; Ermolovich, Yurii V.; Konstantinova, Olga V.2011Journal of Labelled Compounds and Radiopharmaceuticals1.1.
Improved Synthesis of 28-NorbrassinolideKhripach, Vladimir A.; Zhabinskii, Vladimir N.; Ermolovich, Yurii V.2010Synthetic Communications1.1.