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Janeli Viil

https://www.etis.ee/CV/Janeli_Viil/est
3.08.1983
janeli.viil@ut.ee

Teenistuskäik

Haridustee
1990–2016   
1990-2002 Haapsalu Gümnaasium; 2002-2005 Tartu Ülikool, Bioloogia-geograafiateaduskond, bakalaureuseõpe geenitehnoloogias ; 2005-2007 Tartu Ülikool, Bioloogia-geograafiateaduskond, magistriõpe geenitehnoloogias; 1.09.2008-5.09.2016 Tartu Ülikool, Loodus- ja täppisteaduste valdkond, doktoriõpe rakubioloogias

Kvalifikatsioon

Teaduskraadid
Janeli Viil, doktorikraad, 2016, (juh) Viljar Jaks, Studies on cellular and molecular mechanisms that drive normal and regenerative processes in the liver and pathological processes in Dupuytren´s contracture; date of defence 30.08.2016 (Terve ja kahjustatud maksa regeneratsioonis ning Dupuytren'i kontraktuuri progressioonis osalevate rakuliste ja molekulaarsete mehhanismide uurimine; kaitsmise kuupäev 30.08.2016), Tartu Ülikool, Loodus- ja täppisteaduste valdkond, molekulaar- ja rakubioloogia instituut.
Janeli Viil, magistrikraad, 2007, (juh) Lilian Kadaja-Saarepuu, CD43 mõju Fas-vahendatud apoptoosile ja Fas ekspressioonile, Tartu Ülikool, Bioloogia-geograafiateaduskond, Molekulaar- ja rakubioloogia instituut.
 
 
Teadustöö põhisuunad
ETIS KLASSIFIKAATOR: 3. Terviseuuringud; 3.11. Terviseuuringutega seotud uuringud, näiteks biokeemia, geneetika, mikrobioloogia, biotehnoloogia, molekulaarbioloogia, rakubioloogia, biofüüsika ja bioinformaatika; CERCS KLASSIFIKAATOR: B210 Histoloogia, tsütokeemia, histokeemia, koekultuurid

Lõppenud projektid

Publikatsioonid

Klass
Aasta
Publikatsioon
 
1.1.
2020
Dissanayake, Keerthie; Nõmm, Monika; Lättekivi, Freddy; Ressaissi, Yosra; Godakumara, Kasun; Lavrits, Arina; Midekessa, Getnet; Viil, Janeli; Bæk, Rikke; Jørgensen, Malene Møller; Bhattacharjee, Sourav; Andronowska, Aneta; Salumets, Andres; Jaakma, Ülle; Fazeli, Alireza (2020). Individually cultured bovine embryos produce extracellular vesicles that have the potential to be used as non-invasive embryo quality markers. Theriogenology, 149, 104−116. DOI: 10.1016/j.theriogenology.2020.03.008.
1.1.
2020
Reshi, Qurat Ul Ain; Viil, Janeli; Ord, James; Lattekivi, Freddy; Godakumara, Kasun; Hasan, Mohammad Mehedi; Nomm, Monika; Jaager, Kersti; Velthut-Meikas, Agne; Jaakma, Ülle; Salumets, Andres; Fazeli, Alireza (2020). Spermatozoa induce transcriptomic alterations in bovine oviductal epithelial cells prior to initial contact. Journal of Cell Communication and Signaling , 14 (4), 439−451. DOI: 10.1007/s12079-020-00575-2.
1.1.
2020
Hasan, Mohammad Mehedi; Viil, Janeli; Lattekivi, Freddy; Ord, James; Reshi, Qurat Ul Ain; Jaager, Kersti; Velthut-Meikas, Agne; Andronowska, Aneta; Jaakma, Ulle; Salumets, Andres; Fazeli, Alireza (2020). Bovine Follicular Fluid and Extracellular Vesicles Derived from Follicular Fluid Alter the Bovine Oviductal Epithelial Cells Transcriptome. International Journal of Molecular Sciences, 21 (15), ARTN 5365. DOI: 10.3390/ijms21155365.
1.1.
2020
Rooda, I.; Hasan, M. M.; Roos, K.; Viil, J.; Andronowska, A.; Smolander, O. P.; Jaakma, Ü.; Salumets, A.; Fazeli, A.; Velthut-Meikas, A. (2020). Cellular, extracellular and extracellular vesicular miRNA profiles of pre-ovulatory follicles indicate signaling disturbances in polycystic ovaries. International Journal of Molecular Sciences, 21 (24), 1−23. DOI: 10.3390/ijms21249550.
1.1.
2019
Es-Haghi, Masoumeh; Godakumara, Kasun; Haling, Annika; Lattekivi, Freddy; Lavrits, Arina; Viil, Janeli; Andronowska, Aneta; Nafee, Tamer; James, Victoria; Jaakma, Ulle; Salumets, Andres; Fazeli, Alireza (2019). Specific trophoblast transcripts transferred by extracellular vesicles affect gene expression in endometrial epithelial cells and may have a role in embryo-maternal crosstalk. Cell Communication and Signaling, 17 (1), ARTN 146. DOI: 10.1186/s12964-019-0448-x.
5.2.
2019
Midekessa, Getnet B.; Godakumara, Kasun; Reimann,Ene; Viil, Janeli; Lättekivi, Freddy; Dissanayake, Keerthie; Kopanchuk, Sergei; Thurston, Lisa; Ebbens, Stephen; Rinken, Ago; Rinken, Toonika; (2019). The effect of antibody binding on the zeta potential of extracellularvesicles secreted by cultured human choriocarcinoma cells. ISEV2019 Abstract Book: ISEV 2019. 25-28. 04.2019. Kyoto, Japan. Taylor and Francis, 336−336.
1.1.
2017
Viil, Janeli; Klaas, Mariliis; Valter, Kadri; Belitškin, Denis; Ilmjärv, Sten; Jaks, Viljar (2017). A label-retaining but unipotent cell population resides in biliary compartment of mammalian liver. Scientific Reports, 7, Article number: 40322. DOI: 10.1038/srep40322.
1.1.
2016
Klaas, Mariliis; Kangur, Triin; Viil, Janeli; Mäemets-Allas, Kristina; Minajeva, Ave; Vadi, Krista; Antsov, Mikk; Lapidus, Natalia; Järvekülg, Martin; Jaks, Viljar (2016). The alterations in the extracellular matrix composition guide the repair of damaged liver tissue. Scientific Reports, 6, Article number: 27398. DOI: 10.1038/srep27398.
1.1.
2016
Urgard, Egon; Lorents, Annely; Klaas, Mariliis; Padari, Kärt; Viil, Janeli; Runnel, Toomas; Langel, Kent; Kingo, Külli; Tkaczyk, Eric; Langel, Ülo; Maimets, Toivo; Jaks, Viljar; Pooga, Margus; Rebane, Ana (2016). Pre-administration of PepFect6-microRNA-146a nanocomplexes inhibits inflammatory responses in keratinocytes and in a mouse model of irritant contact dermatitis. Journal of Controlled Release, 235, 195−2014. DOI: 10.1016/j.jconrel.2016.06.006.
1.1.
2015
Mäemets-Allas, K.; Viil, J.; Jaks, V. (2015). A novel inhibitor of AKT1-PDPK1 interaction efficiently suppresses the activity of AKT pathway and restricts tumor growth in vivo. Molecular cancer therapeutics, 28, 17, 144.
1.1.
2015
Viil, J.; Maasalu, K.; Mäemets-Allas, K4., Tamming, L.; Lõhmussaar, K.; Tooming, M.; Ingerpuu, S.; Märtson, A.; Jaks, V. (2015). Laminin-rich blood vessels display activated growth factor signaling and act as the proliferation centers in Dupuytren's contracture. Arthritis Research & Therapy, 17 (1), Article number 144. DOI: 10.1186/s13075-015-0661-y.
1.1.
2012
Balikova, Anna; Jääger, Kersti; Viil, Janeli; Maimets, Toivo; Kadaja-Saarepuu, Lilian (2012). Leukocyte marker CD43 promotes cell growth in co-operation with β-catenin in non-hematopoietic cancer cells. International Journal of Oncology, 41, 299−309.
1.1.
2008
Kadaja-Saarepuu, L.; Laos, S.; Jääger, K.; Viil, J.; Balikova, A.; Lõoke, M.; Hansson, G.C.; Maimets, T. (2008). CD43 promotes cell growth and helps to evade FAS-mediated apoptosis in nonhematopoietic cancer cells lacking the tumor suppressors p53 or ARF. Oncogene, 27 (12), 1705−1715.
25.03.2021

Janeli Viil

https://www.etis.ee/CV/Janeli_Viil/eng
3.08.1983
737 5056
janeli.viil@ut.ee

Career

Education
1990–2016   
1990-2002 Haapsalu Gymnasium; 2002-2005 University of Tartu, Faculty of Biology and Geography, bachelor's studies in genetechnology; University of Tartu, Faculty of Biology and Geography,master`s studies in genetechnology; 1.09.2008-5.09.2016 University of Tartu, Faculty of Science and Technology, doctoral studies in cell biology

Qualifications

Academic degrees
Janeli Viil, Doctor's Degree, 2016, (sup) Viljar Jaks, Studies on cellular and molecular mechanisms that drive normal and regenerative processes in the liver and pathological processes in Dupuytren´s contracture; date of defence 30.08.2016, University of Tartu, Faculty of Science and Technology, Institute of Molecular and Cell Biology.
Janeli Viil, Master's Degree, 2007, (sup) Lilian Kadaja-Saarepuu, CD43 mõju Fas-vahendatud apoptoosile ja Fas ekspressioonile (The impact of CD43 on Fas-mediated apoptosis and Fas expression), University of Tartu, Faculty of Biology and Geography, Institute of Molecular and Cell Biology.
 
 
Fields of research
ETIS CLASSIFICATION: 3. Health; 3.11. Biochemistry, Genetics, Microbiology, Biotechnology, Molecular Biology, Cell Biology, Biophysics and Bioinformatics relating to Health Studies; CERCS CLASSIFICATION: B210 Histology, cytochemistry, histochemistry, tissue culture
 
 

Completed projects

Publications

Category
Year
Publication
 
1.1.
2020
Dissanayake, Keerthie; Nõmm, Monika; Lättekivi, Freddy; Ressaissi, Yosra; Godakumara, Kasun; Lavrits, Arina; Midekessa, Getnet; Viil, Janeli; Bæk, Rikke; Jørgensen, Malene Møller; Bhattacharjee, Sourav; Andronowska, Aneta; Salumets, Andres; Jaakma, Ülle; Fazeli, Alireza (2020). Individually cultured bovine embryos produce extracellular vesicles that have the potential to be used as non-invasive embryo quality markers. Theriogenology, 149, 104−116. DOI: 10.1016/j.theriogenology.2020.03.008.
1.1.
2020
Reshi, Qurat Ul Ain; Viil, Janeli; Ord, James; Lattekivi, Freddy; Godakumara, Kasun; Hasan, Mohammad Mehedi; Nomm, Monika; Jaager, Kersti; Velthut-Meikas, Agne; Jaakma, Ülle; Salumets, Andres; Fazeli, Alireza (2020). Spermatozoa induce transcriptomic alterations in bovine oviductal epithelial cells prior to initial contact. Journal of Cell Communication and Signaling , 14 (4), 439−451. DOI: 10.1007/s12079-020-00575-2.
1.1.
2020
Hasan, Mohammad Mehedi; Viil, Janeli; Lattekivi, Freddy; Ord, James; Reshi, Qurat Ul Ain; Jaager, Kersti; Velthut-Meikas, Agne; Andronowska, Aneta; Jaakma, Ulle; Salumets, Andres; Fazeli, Alireza (2020). Bovine Follicular Fluid and Extracellular Vesicles Derived from Follicular Fluid Alter the Bovine Oviductal Epithelial Cells Transcriptome. International Journal of Molecular Sciences, 21 (15), ARTN 5365. DOI: 10.3390/ijms21155365.
1.1.
2020
Rooda, I.; Hasan, M. M.; Roos, K.; Viil, J.; Andronowska, A.; Smolander, O. P.; Jaakma, Ü.; Salumets, A.; Fazeli, A.; Velthut-Meikas, A. (2020). Cellular, extracellular and extracellular vesicular miRNA profiles of pre-ovulatory follicles indicate signaling disturbances in polycystic ovaries. International Journal of Molecular Sciences, 21 (24), 1−23. DOI: 10.3390/ijms21249550.
1.1.
2019
Es-Haghi, Masoumeh; Godakumara, Kasun; Haling, Annika; Lattekivi, Freddy; Lavrits, Arina; Viil, Janeli; Andronowska, Aneta; Nafee, Tamer; James, Victoria; Jaakma, Ulle; Salumets, Andres; Fazeli, Alireza (2019). Specific trophoblast transcripts transferred by extracellular vesicles affect gene expression in endometrial epithelial cells and may have a role in embryo-maternal crosstalk. Cell Communication and Signaling, 17 (1), ARTN 146. DOI: 10.1186/s12964-019-0448-x.
5.2.
2019
Midekessa, Getnet B.; Godakumara, Kasun; Reimann,Ene; Viil, Janeli; Lättekivi, Freddy; Dissanayake, Keerthie; Kopanchuk, Sergei; Thurston, Lisa; Ebbens, Stephen; Rinken, Ago; Rinken, Toonika; (2019). The effect of antibody binding on the zeta potential of extracellularvesicles secreted by cultured human choriocarcinoma cells. ISEV2019 Abstract Book: ISEV 2019. 25-28. 04.2019. Kyoto, Japan. Taylor and Francis, 336−336.
1.1.
2017
Viil, Janeli; Klaas, Mariliis; Valter, Kadri; Belitškin, Denis; Ilmjärv, Sten; Jaks, Viljar (2017). A label-retaining but unipotent cell population resides in biliary compartment of mammalian liver. Scientific Reports, 7, Article number: 40322. DOI: 10.1038/srep40322.
1.1.
2016
Klaas, Mariliis; Kangur, Triin; Viil, Janeli; Mäemets-Allas, Kristina; Minajeva, Ave; Vadi, Krista; Antsov, Mikk; Lapidus, Natalia; Järvekülg, Martin; Jaks, Viljar (2016). The alterations in the extracellular matrix composition guide the repair of damaged liver tissue. Scientific Reports, 6, Article number: 27398. DOI: 10.1038/srep27398.
1.1.
2016
Urgard, Egon; Lorents, Annely; Klaas, Mariliis; Padari, Kärt; Viil, Janeli; Runnel, Toomas; Langel, Kent; Kingo, Külli; Tkaczyk, Eric; Langel, Ülo; Maimets, Toivo; Jaks, Viljar; Pooga, Margus; Rebane, Ana (2016). Pre-administration of PepFect6-microRNA-146a nanocomplexes inhibits inflammatory responses in keratinocytes and in a mouse model of irritant contact dermatitis. Journal of Controlled Release, 235, 195−2014. DOI: 10.1016/j.jconrel.2016.06.006.
1.1.
2015
Mäemets-Allas, K.; Viil, J.; Jaks, V. (2015). A novel inhibitor of AKT1-PDPK1 interaction efficiently suppresses the activity of AKT pathway and restricts tumor growth in vivo. Molecular cancer therapeutics, 28, 17, 144.
1.1.
2015
Viil, J.; Maasalu, K.; Mäemets-Allas, K4., Tamming, L.; Lõhmussaar, K.; Tooming, M.; Ingerpuu, S.; Märtson, A.; Jaks, V. (2015). Laminin-rich blood vessels display activated growth factor signaling and act as the proliferation centers in Dupuytren's contracture. Arthritis Research & Therapy, 17 (1), Article number 144. DOI: 10.1186/s13075-015-0661-y.
1.1.
2012
Balikova, Anna; Jääger, Kersti; Viil, Janeli; Maimets, Toivo; Kadaja-Saarepuu, Lilian (2012). Leukocyte marker CD43 promotes cell growth in co-operation with β-catenin in non-hematopoietic cancer cells. International Journal of Oncology, 41, 299−309.
1.1.
2008
Kadaja-Saarepuu, L.; Laos, S.; Jääger, K.; Viil, J.; Balikova, A.; Lõoke, M.; Hansson, G.C.; Maimets, T. (2008). CD43 promotes cell growth and helps to evade FAS-mediated apoptosis in nonhematopoietic cancer cells lacking the tumor suppressors p53 or ARF. Oncogene, 27 (12), 1705−1715.
25.03.2021