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Kalle Pärn

https://www.etis.ee/CV/Kalle_Pärn/eng
21.09.1988
kalle.parn@ut.ee

Career

Institutions and positions
01.05.2016–31.08.2016   
University of Tartu, Estonian Genome Center, Research Fellow (1,00)
01.09.2015–30.04.2016   
University of Tartu, Estonian Genome Center, Specialist (1,00)
01.08.2014–31.08.2015   
University of Tartu, Faculty of Science and Technology (old), Institute of Technology, University of Tartu, Junior Research Fellow (0,50)
01.08.2012–31.07.2014   
University of Tartu, Faculty of Science and Technology (old), Institute of Technology, University of Tartu, Specialist (1,00)

Qualifications

Academic degrees
Kalle Pärn, Doctor's Degree, 2015, (sup) Ülo Langel; Andres Merits, Studies on inducible alphavirus-based antitumour strategy mediated by site-specific delivery with activatable cell-penetrating peptides, University of Tartu, Faculty of Science and Technology (old).
Kalle Pärn, Master's Degree, 2012, (sup) Andres Merits; Liane Viru, Mitteviraalsed ülekandesüsteemid viirustpõhiste ülekandesüsteemide jaoks (Non-viral delivery systems for viral delivery systems), University of Tartu, Faculty of Science and Technology (old), Institute of Molecular and Cell Biology, University of Tartu.
 
 

Completed projects

Publications

Category
Year
Publication
 
1.1.
2016
Gormley, Padhraig; Anttila, Verneri; Winsvold, Bendik S; Palta, Priit; Esko, Tonu; Pers, Tune H; Farh, Kai-How; Cuenca-Leon, Ester; Muona, Mikko; Furlotte, Nicholas A; Kurth, Tobias; Ingason, Andres; McMahon, George; Ligthart, Lannie; Terwindt, Gisela M; Kallela, Mikko; Freilinger, Tobias M; Ran, Caroline; Gordon, Scott G; Stam, Anine H ... Palotie, Aarno (2016). Meta-analysis of 375,000 individuals identifies 38 susceptibility loci for migraine. Nature Genetics, 48 (8), 856−866. DOI: 10.1038/ng.3598.
1.1.
2015
Veiman, Kadi-Liis; Künnapuu, Kadri; Lehto, Tõnis; Kiisholts, Kristina; Pärn, Kalle; Langel, Ülo; Kurrikoff, Kaido (2015). PEG shielded MMP sensitive CPPs for efficient and tumor specific gene delivery in vivo. Journal of Controlled Release, 209, 238−247. DOI: 10.1016/j.jconrel.2015.04.038.
3.1.
2015
Pärn, K.; Eriste, E.; Langel, Ü. (2015). The Antimicrobial and Antiviral Applications of Cell-Penetrating Peptides. Methods in molecular biology, 1324, 223−245. DOI: 10.1007/978-1-4939-2806-4_15.
1.1.
2013
Pärn, K.; Viru, L.; Lehto, T.; Oskolkov, N.; Langel, Ü.; Merits, A. (2013). Transfection of Infectious RNA and DNA/RNA Layered Vectors of Semliki Forest Virus by the Cell-Penetrating Peptide Based Reagent PepFect6. PLoS ONE, 8 (7), e69659. DOI: 10.1371/journal.pone.0069659.
1.1.
2013
Vasconselos, L.; Pärn, K.; Langel, Ü. (2013). Therapeutic potential of cell-penetrating peptides. Therapeutic Delivery, 4 (5), 573−591.10.4155/tde.13.22.
1.1.
2011
Viru, L.; Heller, G.; Lehto, T.; Pärn, K.; El Andaloussi, S.; Langel, Ü.; Merits, A. (2011). Novel viral vectors utilizing intron splice-switch to activate genome rescue, expression and replication in targeted cells. Virology Journal, 8 (1), 243.
18.02.2020

Kalle Pärn

https://www.etis.ee/CV/Kalle_Pärn/est
21.09.1988
kalle.parn@ut.ee

Teenistuskäik

Töökohad ja ametid
01.05.2016–31.08.2016   
University of Tartu, Estonian Genome Center, funktsionaalse genoomika teadur (1,00)
01.09.2015–30.04.2016   
University of Tartu, Estonian Genome Center, spetsialist (1,00)
01.08.2014–31.08.2015   
Tartu Ülikool, Loodus- ja tehnoloogiateaduskond, Tartu Ülikooli Tehnoloogiainstituut, molekulaarbioloogia nooremteadur (0,50)
01.08.2012–31.07.2014   
Tartu Ülikool, Loodus- ja tehnoloogiateaduskond, Tartu Ülikooli Tehnoloogiainstituut, spetsialist (1,00)

Kvalifikatsioon

Teaduskraadid
Kalle Pärn, Doctor's Degree, 2015, (sup) Ülo Langel; Andres Merits, Studies on inducible alphavirus-based antitumour strategy mediated by site-specific delivery with activatable cell-penetrating peptides, University of Tartu, Faculty of Science and Technology (old).
Kalle Pärn, Master's Degree, 2012, (sup) Andres Merits; Liane Viru, Mitteviraalsed ülekandesüsteemid viirustpõhiste ülekandesüsteemide jaoks (Non-viral delivery systems for viral delivery systems), University of Tartu, Faculty of Science and Technology (old), Institute of Molecular and Cell Biology, University of Tartu.
 
 

Lõppenud projektid

Publikatsioonid

Klass
Aasta
Publikatsioon
 
1.1.
2016
Gormley, Padhraig; Anttila, Verneri; Winsvold, Bendik S; Palta, Priit; Esko, Tonu; Pers, Tune H; Farh, Kai-How; Cuenca-Leon, Ester; Muona, Mikko; Furlotte, Nicholas A; Kurth, Tobias; Ingason, Andres; McMahon, George; Ligthart, Lannie; Terwindt, Gisela M; Kallela, Mikko; Freilinger, Tobias M; Ran, Caroline; Gordon, Scott G; Stam, Anine H ... Palotie, Aarno (2016). Meta-analysis of 375,000 individuals identifies 38 susceptibility loci for migraine. Nature Genetics, 48 (8), 856−866. DOI: 10.1038/ng.3598.
1.1.
2015
Veiman, Kadi-Liis; Künnapuu, Kadri; Lehto, Tõnis; Kiisholts, Kristina; Pärn, Kalle; Langel, Ülo; Kurrikoff, Kaido (2015). PEG shielded MMP sensitive CPPs for efficient and tumor specific gene delivery in vivo. Journal of Controlled Release, 209, 238−247. DOI: 10.1016/j.jconrel.2015.04.038.
3.1.
2015
Pärn, K.; Eriste, E.; Langel, Ü. (2015). The Antimicrobial and Antiviral Applications of Cell-Penetrating Peptides. Methods in molecular biology, 1324, 223−245. DOI: 10.1007/978-1-4939-2806-4_15.
1.1.
2013
Pärn, K.; Viru, L.; Lehto, T.; Oskolkov, N.; Langel, Ü.; Merits, A. (2013). Transfection of Infectious RNA and DNA/RNA Layered Vectors of Semliki Forest Virus by the Cell-Penetrating Peptide Based Reagent PepFect6. PLoS ONE, 8 (7), e69659. DOI: 10.1371/journal.pone.0069659.
1.1.
2013
Vasconselos, L.; Pärn, K.; Langel, Ü. (2013). Therapeutic potential of cell-penetrating peptides. Therapeutic Delivery, 4 (5), 573−591.10.4155/tde.13.22.
1.1.
2011
Viru, L.; Heller, G.; Lehto, T.; Pärn, K.; El Andaloussi, S.; Langel, Ü.; Merits, A. (2011). Novel viral vectors utilizing intron splice-switch to activate genome rescue, expression and replication in targeted cells. Virology Journal, 8 (1), 243.
18.02.2020

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  • Found 5 results
ProgramTypeNumberNameProject startProject endPrincipal investigatorInstitutionFinancing
ETFETF9421Probing the macromolecular architecture of alphavirus replication complex using mutational scanning of protein surfaces, homologous domain swapping and crosslink/ms analyses01.01.201231.12.2014Valeria LullaUniversity of Tartu, Faculty of Science and Technology (old), Institute of Technology, University of Tartu36 000,00 EUR
ETFETF7407Alphavirus replication, inhibition and virus-host interactions.01.01.200831.12.2011Andres MeritsUniversity of Tartu, Faculty of Science and Technology (old), Institute of Technology, University of Tartu; University of Tartu, Faculty of Science and Technology (old), Institute of Technology, University of Tartu; University of Tartu, Faculty of Science and Technology (old)66 495,46 EUR
TKSLTMR16142T (TK142)Centre of Excellence for Genomics and Translational Medicine (TK142)01.01.201601.03.2023Andres MetspaluUniversity of Tartu, Estonian Genome Center 4 474 349,50 EUR
SFSF0180027s08Tissue-specific delivery vectors01.01.200831.12.2013Ülo LangelUniversity of Tartu, Faculty of Science and Technology (old), Institute of Technology, University of Tartu600 272,61 EUR
IUTIUT20-26Trans-barrier targeting01.01.201431.12.2019Ülo LangelUniversity of Tartu, Faculty of Science and Technology, Institute of Technology889 200,00 EUR