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Koit Aasumets

https://www.etis.ee/CV/Koit_Aasumets/eng
8.03.1993
koit.aasumets@ut.ee
http://

Career

Institutions and positions
01.10.2020–...   
University of Eastern Finland, Researcher (1,00)
01.09.2020–31.08.2021   
University of Tartu, Faculty of Science and Technology, Institute of Technology, Junior Research Fellow in Plant Biochemistry (0,50)
2014–2016   
University of Tartu, Faculty of Medicine, Institute of Biomedicine and Translational Medicine, Assistant (0,25)
 
 
Education
2017–2022   
University of Tartu, doctoral candidate in biomedical technology
2015–2017   
University of Tartu, MSc
2012–2015   
University of Tartu, BSc
2009–2012   
Rakvere Reaalgümnaasium, reaal-loodus suund
2000–2009   
Muuga Basic School
 
 
Additional information

Qualifications

Academic degrees
Koit Aasumets, Doctor's Degree, 2022, (sup) Joachim Matthias Gerhold; Hannes Kollist, The dynamics of human mitochondrial nucleoids within the mitochondrial network, University of Tartu, Faculty of Science and Technology, Institute of Technology
Koit Aasumets, Master's Degree, 2017, (sup) Joachim Matthias Gerhold, Mitokondriaalsete nukleoidide ja mitokondritega seotud ER-membraanide (MAM) koosmõju inimrakkudes (The interplay between mitochondrial nucleoids and mitochondria associated ER-membranes (MAM) in human cultured cells), University of Tartu, Faculty of Science and Technology (old), Institute of Molecular and Cell Biology, University of Tartu, Chair of Biophysics and Plant Physiology.
 
 
Honours & awards
2017, Koit Aasumets, A diploma for master's thesis issued by Estonian National Contest for University Students (The Estonian Research Council)
 
 
Fields of research
ETIS RESEARCH FIELD: 1. Biosciences and Environment; 1.1. Biochemistry; CERCS RESEARCH FIELD: P320 Nucleic acids, protein synthesis
 
 

Completed projects

Publications

Category
Year
Publication
 
1.1.
2021
Aasumets, Koit; Basikhina, Yuliya; Pohjoismäki, Jaakko L.; Goffart, Steffi; Gerhold, Joachim (2021). TFAM knockdown-triggered mtDNA-nucleoid aggregation and a decrease in mtDNA copy number induce the reorganization of nucleoid populations and mitochondria-associated ER-membrane contacts. Biochemistry and Biophysics Reports, 28, 101142. DOI: 10.1016/j.bbrep.2021.101142.
1.1.
2020
Ianevski, Aleksandr; Kulesskiy, Evgeny; Krpina, Klara; Lou, Guofeng; Aman, Yahyah; Bugai, Andrii; Aasumets, Koit; Akimov, Yevhen; Bulanova, Daria; Gildemann, Kiira; Arutyunyan, Albert F; Susova, Olga Yu; Zhuze, Alexei L; Ji, Ping; Wang, Wei; Holien, Toril; Bugge, Marit; Zusinaite, Eva; Oksenych, Valentyn; Lysvand, Hilde ... Kainov, Denis E (2020). Chemical, Physical and Biological Triggers of Evolutionary Conserved Bcl-xL-Mediated Apoptosis. Cancers, 12 (6), 1694. DOI: 10.3390/cancers12061694.
1.1.
2019
Wagner, Anita; Hofmeister, Olga; Rolland, Stephane G.; Maiser, Andreas; Aasumets, Koit; Schmitt, Sabine; Schorpp, Kenji; Feuchtinger, Annette; Hadian, Kamyar; Schneider, Sabine; Zischka, Hans; Leonhardt, Heinrich; Conradt, Barbara; Gerhold, Joachim M.; Wolf, Alexander (2019). Mitochondrial Alkbh1 localises to mtRNA granules and its knockdown induces mitochondrial UPR in humans and C. elegans. Journal of Cell Science, jcs.223891. DOI: 10.1242/jcs.223891.
1.1.
2018
Hangas, Anu; Aasumets, Koit; Kekäläinen, Nina J; Paloheinä, Mika; Pohjoismäki, Jaakko L; Gerhold, Joachim M.; Goffart, Steffi (2018). Ciprofloxacin impairs mitochondrial DNA replication initiation through inhibition of Topoisomerase 2. Nucleic Acids Research, 48 (18), 9625−9636. DOI: 10.1093/nar/gky793.
26.01.2022

Koit Aasumets

https://www.etis.ee/CV/Koit_Aasumets/est
8.03.1993
koit.aasumets@ut.ee

Teenistuskäik

Töökohad ja ametid
01.10.2020–...   
Ida-Soome Ülikool, Teadur (1,00)
01.09.2020–31.08.2021   
Tartu Ülikool, Loodus- ja täppisteaduste valdkond, tehnoloogiainstituut, taimebiokeemia nooremteadur (0,50)
2014–2016   
Tartu Ülikool, Meditsiiniteaduste valdkond, Bio- ja siirdemeditsiini instituut, Assistent (0,25)
 
 
Haridustee
2017–2022   
Tartu Ülikool, biomeditsiini tehnoloogia doktorant
2015–2017   
Tartu Ülikool, geenitehnoloogia magister
2012–2015   
Tartu Ülikool, geenitehnoloogia bakalaureus
2009–2012   
Rakvere Reaalgümnaasium, reaal-loodus suund
2000–2009   
Muuga Põhikool
 
 
Lisainfo

Kvalifikatsioon

Teaduskraadid
Koit Aasumets, Doctor's Degree, 2022, (sup) Joachim Matthias Gerhold; Hannes Kollist, The dynamics of human mitochondrial nucleoids within the mitochondrial network, University of Tartu, Faculty of Science and Technology, Institute of Technology
Koit Aasumets, Master's Degree, 2017, (sup) Joachim Matthias Gerhold, Mitokondriaalsete nukleoidide ja mitokondritega seotud ER-membraanide (MAM) koosmõju inimrakkudes (The interplay between mitochondrial nucleoids and mitochondria associated ER-membranes (MAM) in human cultured cells), University of Tartu, Faculty of Science and Technology (old), Institute of Molecular and Cell Biology, University of Tartu, Chair of Biophysics and Plant Physiology.
 
 
Teaduspreemiad ja tunnustused
2017, Koit Aasumets, Üliõpilaste teadustööde konkursi tänukiri magistritöö eest (Eesti Teadusagentuur)
 
 
Teadustöö põhisuunad
ETIS VALDKOND: 1. Bio- ja keskkonnateadused; 1.1. Biokeemia; CERCS VALDKOND: P320 Nukleiinhappesüntees, proteiinisüntees

Lõppenud projektid

Publikatsioonid

Klass
Aasta
Publikatsioon
 
1.1.
2021
Aasumets, Koit; Basikhina, Yuliya; Pohjoismäki, Jaakko L.; Goffart, Steffi; Gerhold, Joachim (2021). TFAM knockdown-triggered mtDNA-nucleoid aggregation and a decrease in mtDNA copy number induce the reorganization of nucleoid populations and mitochondria-associated ER-membrane contacts. Biochemistry and Biophysics Reports, 28, 101142. DOI: 10.1016/j.bbrep.2021.101142.
1.1.
2020
Ianevski, Aleksandr; Kulesskiy, Evgeny; Krpina, Klara; Lou, Guofeng; Aman, Yahyah; Bugai, Andrii; Aasumets, Koit; Akimov, Yevhen; Bulanova, Daria; Gildemann, Kiira; Arutyunyan, Albert F; Susova, Olga Yu; Zhuze, Alexei L; Ji, Ping; Wang, Wei; Holien, Toril; Bugge, Marit; Zusinaite, Eva; Oksenych, Valentyn; Lysvand, Hilde ... Kainov, Denis E (2020). Chemical, Physical and Biological Triggers of Evolutionary Conserved Bcl-xL-Mediated Apoptosis. Cancers, 12 (6), 1694. DOI: 10.3390/cancers12061694.
1.1.
2019
Wagner, Anita; Hofmeister, Olga; Rolland, Stephane G.; Maiser, Andreas; Aasumets, Koit; Schmitt, Sabine; Schorpp, Kenji; Feuchtinger, Annette; Hadian, Kamyar; Schneider, Sabine; Zischka, Hans; Leonhardt, Heinrich; Conradt, Barbara; Gerhold, Joachim M.; Wolf, Alexander (2019). Mitochondrial Alkbh1 localises to mtRNA granules and its knockdown induces mitochondrial UPR in humans and C. elegans. Journal of Cell Science, jcs.223891. DOI: 10.1242/jcs.223891.
1.1.
2018
Hangas, Anu; Aasumets, Koit; Kekäläinen, Nina J; Paloheinä, Mika; Pohjoismäki, Jaakko L; Gerhold, Joachim M.; Goffart, Steffi (2018). Ciprofloxacin impairs mitochondrial DNA replication initiation through inhibition of Topoisomerase 2. Nucleic Acids Research, 48 (18), 9625−9636. DOI: 10.1093/nar/gky793.
26.01.2022

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ProgramTypeNumberNameProject startProject endPrincipal investigatorInstitutionFinancing
MUUMARMP11194RDevelopment of tumor penetrating peptides for glioma targeting01.01.201231.12.2016Tambet TeesaluUniversity of Tartu, Faculty of Medicine, Departement of General and Molecular Pathology; University of Tartu, Faculty of Medicine, Institute of Biomedicine and Translational Medicine; University of Tartu, Faculty of Medicine, Institute of Biomedicine and Translational Medicine1 499 931,00 EUR
PUT; PUT_SPPUT610A network for life? Studying dynamics of the mitochondrial- and ER-networks and their relation to mtDNA maintenance and mitochondrial membrane-lipid composition.01.01.201531.12.2018Joachim Matthias GerholdUniversity of Tartu, Faculty of Science and Technology, Institute of Molecular and Cell Biology225 600,00 EUR