Konstantin Popadin
https://www.etis.ee/CV/Konstantin_Popadin/est
Teenistuskäik
Töökohad ja ametid
2017–...
Immanuel Kant Baltic Federal University, Kaliningrad, Russia, Külalisprofessor (1,00)
2015–...
Center of Integrative Genomics, University of Lausanne, Switzerland, Vanemassistent (1,00)
2011–2015
Department of Genetic Medicine and Development, University of Geneva, Switzerland, Vanemassistent (1,00)
2010–2011
Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, USA, Nooremassistent (1,00)
Haridustee
2001–2005
PhD, Department of Genetics, Lomonosov Moscow State University, Russia
1996–2001
Master Science in Biology, Lomonosov Moscow State University, Russia
Teadusorganisatsiooniline ja -administratiivne tegevus
2005−2010
bio-statistician, project manager in clinical research company, Russia
Loometöö
Science communication through TV and radio shows, public lectures and popular papers (Moscow, Kaliningrad) http://m.polit.ru/lector/konstantin_p/, https://polit.ru/article/2014/11/24/anons_06_12/, https://elementy.ru/novosti_nauki/t/1626930/Konstantin_Popadin.
Teenistuskäigu lisainfo
Together with my colleagues around the globe I moderate international evolutionary journal club every week.
Details are following this link:
https://docs.google.com/presentation/d/1LsvkcIVrvYWopy4lydVDgdr454-UMjlFGNXTkdvi3vc/edit?usp=sharing ;
Details are following this link:
https://docs.google.com/presentation/d/1LsvkcIVrvYWopy4lydVDgdr454-UMjlFGNXTkdvi3vc/edit?usp=sharing ;
Kvalifikatsioon
Teadustöö põhisuunad
VALDKOND: 1. Bio- ja keskkonnateadused; 1.3. Geneetika; CERCS ERIALA: B220 Geneetika, tsütogeneetika
Lisainfo
Currently I supervise and co-supervise three PhD students in the Immanuel Kant Baltic Federal University and 11 master students.
Juhendatud väitekirjad
Juhendatud järeldoktorid
-
01.09.2018−01.09.2021 Alina G. Mikhailova "mtDNA mutational spectrum" Immanuel Kant Baltic Federal University, Kaliningrad, Russia
Publikatsioonid
Klass
Aasta
Publikatsioon
1.1.
2019
2.5.
2019
6.7.
2019
1.1.
2018
6.8.
2018
1.1.
2017
1.1.
2017
1.1.
2017
6.7.
2017
6.8.
2017
1.1.
2016
1.1.
2016
1.1.
2016
1.1.
2015
1.1.
2015
1.1.
2015
1.1.
2014
1.1.
2014
6.8.
2014
6.8.
2014
1.1.
2013
1.1.
2013
1.1.
2013
1.1.
2013
6.8.
2010
1.1.
2007
1.1.
2007
1.1.
2007
1.1.
2007
1.1.
2003
24.04.2019
Konstantin Popadin
https://www.etis.ee/CV/Konstantin_Popadin/eng
28.05.1979
konstantin.popadin@unil.ch
Career
Institution(s) and position(s)
2017–...
Immanuel Kant Baltic Federal University, Kaliningrad, Russia, Visiting Professor (1,00)
2015–...
Center of Integrative Genomics, University of Lausanne, Switzerland, Senior PostDoc (1,00)
2011–2015
Department of Genetic Medicine and Development, University of Geneva, Switzerland, PostDoc (1,00)
2010–2011
Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, USA, PostDoc (1,00)
Education
2001–2005
PhD, Department of Genetics, Lomonosov Moscow State University, Russia
1996–2001
Master Science in Biology, Lomonosov Moscow State University, Russia
R&D related managerial and administrative work
2005−2010
bio-statistician, project manager in clinical research company, Russia
Creative work
Science communication through TV and radio shows, public lectures and popular papers (Moscow, Kaliningrad) http://m.polit.ru/lector/konstantin_p/, https://polit.ru/article/2014/11/24/anons_06_12/, https://elementy.ru/novosti_nauki/t/1626930/Konstantin_Popadin.
Additional career information
Together with my colleagues around the globe I moderate international evolutionary journal club every week.
Details are following this link:
https://docs.google.com/presentation/d/1LsvkcIVrvYWopy4lydVDgdr454-UMjlFGNXTkdvi3vc/edit?usp=sharing ;
Details are following this link:
https://docs.google.com/presentation/d/1LsvkcIVrvYWopy4lydVDgdr454-UMjlFGNXTkdvi3vc/edit?usp=sharing ;
Qualifications
Field of research
FIELD OF RESEARCH: 1. Biosciences and Environment; 1.3. Genetics; CERCS SPECIALITY: B220 Genetics, cytogenetics ; SPECIALITY: population genetics, medical genetics
Additional information
Currently I supervise and co-supervise three PhD students in the Immanuel Kant Baltic Federal University and 11 master students.
Supervised dissertations
Supervision of postdoctoral researchers
-
01.09.2018−01.09.2021 Alina G. Mikhailova "mtDNA mutational spectrum" (Immanuel Kant Baltic Federal University, Kaliningrad, Russia)
Publications
Category
Year
Publication
1.1.
2019
2.5.
2019
6.7.
2019
1.1.
2018
6.8.
2018
1.1.
2017
1.1.
2017
1.1.
2017
6.7.
2017
6.8.
2017
1.1.
2016
1.1.
2016
1.1.
2016
1.1.
2015
1.1.
2015
1.1.
2015
1.1.
2014
1.1.
2014
6.8.
2014
6.8.
2014
1.1.
2013
1.1.
2013
1.1.
2013
1.1.
2013
6.8.
2010
1.1.
2007
1.1.
2007
1.1.
2007
1.1.
2007
1.1.
2003
24.04.2019
| Publikatsioon | Autorid | Aasta | Väljaande pealkiri | Klassifikaator | Fail | Asutused | |
|---|---|---|---|---|---|---|---|
| MtProtEvol: The resource presenting molecular evolution analysis of proteins involved in the function of Vertebrate mitochondria 06 Biological Sciences 0604 Genetics | Kuzminkova, A.A.; Sokol, A.D.; Ushakova, K.E.; Popadin, K.Y.; Gunbin, K.V. | 2019 | BMC Evolutionary Biology | 1.1. | |||
| Deleterious in late life mitochondrial alleles and aging: secrets of Japanese centenarians | Mikhailova, Alina; Shamansky, Viktor; Bazykin, Georgii A.; Mazunin, Ilia; Gunbin, Konstantin; Kunz, Wolfram; Reymond, Alexandre; Tanaka, Masashi; Khrapko, Konstantin; Popadin, Konstantin | 2019 | Deleterious in late life mitochondrial alleles and aging: secrets of Japanese centenarians | 2.5. | Tartu Ülikool, Tartu Ülikooli genoomika instituut | ||
| Mitochondrial mutational spectrum provides an universal marker of cellular and organismal longevity | Mikhaylova, A. G.; Mikhailova, A. A.; Ushakova, K.; Tretiakov, E.; Yurchenko, A.; Zazhytska, M.; Knorre, D.A.; Zdobnov, E.; Fleischmann, Z.; Annis, S.; Franco, M.; Wasko, K.; Kunz, W.S.; Mazunin, I.; Nikolaev, S.; Reymond, A.; Khrapko, K.; Gunbin, K.; Popadin, K. | 2019 | Mitochondrial mutational spectrum provides an universal marker of cellular and organismal longevity | 6.7. | |||
| Slightly deleterious genomic variants and transcriptome perturbations in Down syndrome embryonic selection | Popadin, K.; Peischl, S.; Garieri, M.; Reza Sailani, M.; Letourneau, A.; Santoni, F.; Lukowski, S.W.; Bazykin, G.A.; Nikolaev, S.; Meyer, D.; Excoffier, L.; Reymond, A.; Antonarakis, S.E.; | 2018 | Genome Research | 1.1. | |||
| Additional evidence of the link between mtDNA copy number and the body mass index | Skuratovskaia, D.A.; Sofronova, J.K.; Zatolokin, P.A.; Popadin, K.Y.; Vasilenko, M.A.; Litvinova, L.S.; Mazunin, I.O.; | 2018 | Mitochondrial DNA Part A: DNA Mapping, Sequencing, and Analysis | 6.8. | |||
| Data on the time of integration of the human mitochondrial pseudogenes (NUMTs) into the nuclear genome | Gunbin, K.; Peshkin, L.; Popadin, K.; Annis, S.; Ackermann, R.R.; Khrapko, K. | 2017 | Data in Brief | 1.1. | |||
| The genomic landscape of human cellular circadian variation points to a novel role for the signalosome | Gaspar, L.; Howald, C.; Popadin, K.; Maier, B.; Mauvoisin, D.; Moriggi, E.; Gutierrez-Arcelus, M.; Falconnet, E.; Borel, C.; Kunz, D.; Kramer, A.; Gachon, F.; Dermitzakis, E.T.; Antonarakis, S.E.; Brown, S.A. | 2017 | eLife | 1.1. | |||
| The Immune Signaling Adaptor LAT Contributes to the Neuroanatomical Phenotype of 16p11.2 BP2-BP3 CNVs | Loviglio, M.N.; Arbogast, T.; Jønch, A.E.; Collins, S.C.; Popadin, K.; Bonnet, C.S.; Giannuzzi, G.; Maillard, A.M.; Jacquemont, S.; Loviglio, M.N.; Jønch, A.E.; Popadin, K.; Giannuzzi, G.; Maillard, A.M.; Fagerberg, C.; Andersen, C.B.; Doco-Fenzy, M.; Delrue, M.-A.; Faivre, L.; Arveiler, B. ... | 2017 | American Journal of Human Genetics | 1.1. | |||
| Intra- and inter-chromosomal chromatin interactions mediate genetic effects on regulatory networks | Delaneau, Olivier; Zazhytska, Marianna; Borel, Christelle; Howald, Cedric; Kumar, Sunil; Ongen, Halit; Popadin, Konstantin; Marbach, Daniel; Ambrosini, Giovanna; Bielser, Deborah; Hacker, David; Romano-Palumbo, Luciana; Ribaux, Pascal; Wiederkehr, Michael; Falconnet, Emilie; Bucher, Philipp; Bergmann, Sven; Antonarakis, Stylianos; Reymond, Alexandre; Dermitzakis, Emmanouil | 2017 | Intra- and inter-chromosomal chromatin interactions mediate genetic effects on regulatory networks | 6.7. | |||
| Integration of mtDNA pseudogenes into the nuclear genome coincides with speciation of the human genus. A hypothesis | Gunbin, K.; Peshkin, L.; Popadin, K.; Annis, S.; Ackermann, R.R.; Khrapko, K.; | 2017 | Mitochondrion | 6.8. | |||
| Amelioration of premature aging in mtDNA mutator mouse by exercise: the interplay of oxidative stress, PGC-1α, p53, and DNA damage. A hypothesis | Safdar, A.; Annis, S.; Kraytsberg, Y.; Laverack, C.; Saleem, A.; Popadin, K.; Woods, D.C.; Tilly, J.L.; Khrapko, K.; | 2016 | Current Opinion in Genetics and Development | 1.1. | |||
| APOBEC-induced mutations in human cancers are strongly enriched on the lagging DNA strand during replication | Seplyarskiy, V.B.; Soldatov, R.A.; Popadin, K.Y.; Antonarakis, S.E.; Bazykin, G.A.; Nikolaev, S.I. | 2016 | Genome Research | 1.1. | |||
| Genomic analysis identifies new drivers and progression pathways in skin basal cell carcinoma | Bonilla, X.; Parmentier, L.; King, B.; Bezrukov, F.; Kaya, G.; Zoete, V.; Seplyarskiy, V.B.; Sharpe, H.J.; McKee, T.; Letourneau, A.; Ribaux, P.G.; Popadin, K.; Basset-Seguin, N.; Chaabene, R.B.; Santoni, F.A.; Andrianova, M.A.; Guipponi, M.; Garieri, M.; Verdan, C.; Grosdemange, K. ... | 2016 | Nature Genetics | 1.1. | |||
| A genetic component of extinction risk in mammals | Polishchuk, L.V.; Popadin, K.Y.; Baranova, M.A.; Kondrashov, A.S. | 2015 | Oikos | 1.1. | |||
| Biased allelic expression in human primary fibroblast single cells | Borel, C.; Ferreira, P.G.; Santoni, F.; Delaneau, O.; Fort, A.; Popadin, K.Y.; Garieri, M.; Falconnet, E.; Ribaux, P.; Guipponi, M.; Padioleau, I.; Carninci, P.; Dermitzakis, E.T.; Antonarakis, S.E.; | 2015 | American Journal of Human Genetics | 1.1. | |||
| DNA-methylation patterns in trisomy 21 using cells from monozygotic twins | Sailani, M.R.; Santoni, F.A.; Letourneau, A.; Borel, C.; Makrythanasis, P.; Hibaoui, Y.; Popadin, K.; Bonilla, X.; Guipponi, M.; Gehrig, C.; Vannier, A.; Carre-Pigeon, F.; Feki, A.; Nizetic, D.; Antonarakis, S.E. | 2015 | PLoS ONE | 1.1. | |||
| Domains of genome-wide gene expression dysregulation in Down's syndrome | Letourneau, A.; Santoni, F.A.; Bonilla, X.; Sailani, M.R.; Gonzalez, D.; Kind, J.; Chevalier, C.; Thurman, R.; Sandstrom, R.S.; Hibaoui, Y.; Garieri, M.; Popadin, K.; Falconnet, E.; Gagnebin, M.; Gehrig, C.; Vannier, A.; Guipponi, M.; Farinelli, L.; Robyr, D.; Migliavacca, E. ... Antonarakis, S.E. | 2014 | Nature | 1.1. | |||
| Gene age predicts the strength of purifying selection acting on gene expression variation in humans | Popadin, K.Y.; Gutierrez-Arcelus, M.; Lappalainen, T.; Buil, A.; Steinberg, J.; Nikolaev, S.I.; Lukowski, S.W.; Bazykin, G.A.; Seplyarskiy, V.B.; Ioannidis, P.; Zdobnov, E.M.; Dermitzakis, E.T.; Antonarakis, S.E. | 2014 | American Journal of Human Genetics | 1.1. | |||
| Mitochondrial DNA mutations and cancer: Lessons from the parathyroid | Popadin, K.; Gunbin, K.V.; Khrapko, K.; | 2014 | American Journal of Pathology | 6.8. | |||
| When man got his mtDNA deletions? | Popadin, K.; Safdar, A.; Kraytsberg, Y.; Khrapko, K.; | 2014 | Aging Cell | 6.8. | |||
| Genetic and epigenetic regulation of human lincrna gene expression | Popadin, K.; Gutierrez-Arcelus, M.; Dermitzakis, E.T.; Antonarakis, S.E. | 2013 | American Journal of Human Genetics | 1.1. | |||
| Purifying selection in mammalian mitochondrial protein-coding genes is highly effective and congruent with evolution of nuclear genes | Popadin, K.Y.; Nikolaev, S.I.; Junier, T.; Baranova, M.; Antonarakis, S.E. | 2013 | Molecular Biology and Evolution | 1.1. | |||
| Roles of mitochondrial dynamics under stressful and normal conditions in yeast cells | Knorre, D.A.; Popadin, K.Y.; Sokolov, S.S.; Severin, F.F.; | 2013 | Oxidative Medicine and Cellular Longevity | 1.1. | |||
| The complex SNP and CNV genetic architecture of the increased risk of congenital heart defects in Down syndrome | Sailani, M.R.; Makrythanasis, P.; Valsesia, A.; Santoni, F.A.; Deutsch, S.; Popadin, K.; Borel, C.; Migliavacca, E.; Sharp, A.J.; Sail, G.D.; Falconnet, E.; Rabionet, K.; Serra-Juhé, C.; Vicari, S.; Laux, D.; Grattau, Y.; Dembour, G.; Megarbane, A.; Touraine, R.; Stora, S. ... Antonarakis, S.E. | 2013 | Genome Research | 1.1. | |||
| Repeats, longevity and the sources of mtDNA deletions: Evidence from 'deletional spectra' | Guo, X.; Popadin, K.Y.; Markuzon, N.; Orlov, Y.L.; Kraytsberg, Y.; Krishnan, K.J.; Zsurka, G.; Turnbull, D.M.; Kunz, W.S.; Khrapko, K.; | 2010 | Trends in Genetics | 6.8. |