28.05.1979
konstantin.popadin@unil.ch

Teenistuskäik

Töökohad ja ametid
2017–...   
Immanuel Kant Baltic Federal University, Kaliningrad, Russia, Külalisprofessor (1,00)
2015–...   
Center of Integrative Genomics, University of Lausanne, Switzerland, Vanemassistent (1,00)
2011–2015   
Department of Genetic Medicine and Development, University of Geneva, Switzerland, Vanemassistent (1,00)
2010–2011   
Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, USA, Nooremassistent (1,00)
 
 
Haridustee
2001–2005   
PhD, Department of Genetics, Lomonosov Moscow State University, Russia
1996–2001   
Master Science in Biology, Lomonosov Moscow State University, Russia
 
 
Teadusorganisatsiooniline ja -administratiivne tegevus
2005−2010   
bio-statistician, project manager in clinical research company, Russia
 
 
Loometöö
Science communication through TV and radio shows, public lectures and popular papers (Moscow, Kaliningrad) http://m.polit.ru/lector/konstantin_p/, https://polit.ru/article/2014/11/24/anons_06_12/, https://elementy.ru/novosti_nauki/t/1626930/Konstantin_Popadin.
 
 
Teenistuskäigu lisainfo
Together with my colleagues around the globe I moderate international evolutionary journal club every week.
Details are following this link:
https://docs.google.com/presentation/d/1LsvkcIVrvYWopy4lydVDgdr454-UMjlFGNXTkdvi3vc/edit?usp=sharing ;

Kvalifikatsioon

 
 
Teadustöö põhisuunad
VALDKOND: 1. Bio- ja keskkonnateadused; 1.3. Geneetika; CERCS ERIALA: B220 Geneetika, tsütogeneetika
 
 
Lisainfo
Currently I supervise and co-supervise three PhD students in the Immanuel Kant Baltic Federal University and 11 master students.

Juhendatud järeldoktorid

  • 01.09.2018−01.09.2021 Alina G. Mikhailova "mtDNA mutational spectrum" Immanuel Kant Baltic Federal University, Kaliningrad, Russia

Publikatsioonid

Klass
Aasta
Publikatsioon
 
1.1.
2019
2.5.
2019
6.7.
2019
1.1.
2018
6.8.
2018
1.1.
2017
1.1.
2017
1.1.
2017
6.7.
2017
6.8.
2017
1.1.
2016
1.1.
2016
1.1.
2016
1.1.
2015
1.1.
2015
1.1.
2015
1.1.
2014
1.1.
2014
6.8.
2014
6.8.
2014
1.1.
2013
1.1.
2013
1.1.
2013
1.1.
2013
6.8.
2010
1.1.
2007
1.1.
2007
1.1.
2007
1.1.
2007
1.1.
2003
24.04.2019
28.05.1979
konstantin.popadin@unil.ch

Career

Institution(s) and position(s)
2017–...   
Immanuel Kant Baltic Federal University, Kaliningrad, Russia, Visiting Professor (1,00)
2015–...   
Center of Integrative Genomics, University of Lausanne, Switzerland, Senior PostDoc (1,00)
2011–2015   
Department of Genetic Medicine and Development, University of Geneva, Switzerland, PostDoc (1,00)
2010–2011   
Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, USA, PostDoc (1,00)
 
 
Education
2001–2005   
PhD, Department of Genetics, Lomonosov Moscow State University, Russia
1996–2001   
Master Science in Biology, Lomonosov Moscow State University, Russia
 
 
R&D related managerial and administrative work
2005−2010   
bio-statistician, project manager in clinical research company, Russia
 
 
Creative work
Science communication through TV and radio shows, public lectures and popular papers (Moscow, Kaliningrad) http://m.polit.ru/lector/konstantin_p/, https://polit.ru/article/2014/11/24/anons_06_12/, https://elementy.ru/novosti_nauki/t/1626930/Konstantin_Popadin.
 
 
Additional career information
Together with my colleagues around the globe I moderate international evolutionary journal club every week.
Details are following this link:
https://docs.google.com/presentation/d/1LsvkcIVrvYWopy4lydVDgdr454-UMjlFGNXTkdvi3vc/edit?usp=sharing ;

Qualifications

 
 
Field of research
FIELD OF RESEARCH: 1. Biosciences and Environment; 1.3. Genetics; CERCS SPECIALITY: B220 Genetics, cytogenetics ; SPECIALITY: population genetics, medical genetics
 
 
Additional information
Currently I supervise and co-supervise three PhD students in the Immanuel Kant Baltic Federal University and 11 master students.

Supervision of postdoctoral researchers

  • 01.09.2018−01.09.2021    Alina G. Mikhailova  "mtDNA mutational spectrum" (Immanuel Kant Baltic Federal University, Kaliningrad, Russia)

Publications

Category
Year
Publication
 
1.1.
2019
2.5.
2019
6.7.
2019
1.1.
2018
6.8.
2018
1.1.
2017
1.1.
2017
1.1.
2017
6.7.
2017
6.8.
2017
1.1.
2016
1.1.
2016
1.1.
2016
1.1.
2015
1.1.
2015
1.1.
2015
1.1.
2014
1.1.
2014
6.8.
2014
6.8.
2014
1.1.
2013
1.1.
2013
1.1.
2013
1.1.
2013
6.8.
2010
1.1.
2007
1.1.
2007
1.1.
2007
1.1.
2007
1.1.
2003
24.04.2019
  • Leitud 30 kirjet
PublikatsioonAutoridAastaVäljaande pealkiriKlassifikaatorFailAsutused
MtProtEvol: The resource presenting molecular evolution analysis of proteins involved in the function of Vertebrate mitochondria 06 Biological Sciences 0604 GeneticsKuzminkova, A.A.; Sokol, A.D.; Ushakova, K.E.; Popadin, K.Y.; Gunbin, K.V.2019BMC Evolutionary Biology1.1.
Deleterious in late life mitochondrial alleles and aging: secrets of Japanese centenariansMikhailova, Alina; Shamansky, Viktor; Bazykin, Georgii A.; Mazunin, Ilia; Gunbin, Konstantin; Kunz, Wolfram; Reymond, Alexandre; Tanaka, Masashi; Khrapko, Konstantin; Popadin, Konstantin2019Deleterious in late life mitochondrial alleles and aging: secrets of Japanese centenarians2.5.Tartu Ülikool, Tartu Ülikooli genoomika instituut
Mitochondrial mutational spectrum provides an universal marker of cellular and organismal longevityMikhaylova, A. G.; Mikhailova, A. A.; Ushakova, K.; Tretiakov, E.; Yurchenko, A.; Zazhytska, M.; Knorre, D.A.; Zdobnov, E.; Fleischmann, Z.; Annis, S.; Franco, M.; Wasko, K.; Kunz, W.S.; Mazunin, I.; Nikolaev, S.; Reymond, A.; Khrapko, K.; Gunbin, K.; Popadin, K.2019Mitochondrial mutational spectrum provides an universal marker of cellular and organismal longevity6.7.
Slightly deleterious genomic variants and transcriptome perturbations in Down syndrome embryonic selectionPopadin, K.; Peischl, S.; Garieri, M.; Reza Sailani, M.; Letourneau, A.; Santoni, F.; Lukowski, S.W.; Bazykin, G.A.; Nikolaev, S.; Meyer, D.; Excoffier, L.; Reymond, A.; Antonarakis, S.E.;2018Genome Research1.1.
Additional evidence of the link between mtDNA copy number and the body mass indexSkuratovskaia, D.A.; Sofronova, J.K.; Zatolokin, P.A.; Popadin, K.Y.; Vasilenko, M.A.; Litvinova, L.S.; Mazunin, I.O.;2018Mitochondrial DNA Part A: DNA Mapping, Sequencing, and Analysis6.8.
Data on the time of integration of the human mitochondrial pseudogenes (NUMTs) into the nuclear genomeGunbin, K.; Peshkin, L.; Popadin, K.; Annis, S.; Ackermann, R.R.; Khrapko, K.2017Data in Brief1.1.
The genomic landscape of human cellular circadian variation points to a novel role for the signalosomeGaspar, L.; Howald, C.; Popadin, K.; Maier, B.; Mauvoisin, D.; Moriggi, E.; Gutierrez-Arcelus, M.; Falconnet, E.; Borel, C.; Kunz, D.; Kramer, A.; Gachon, F.; Dermitzakis, E.T.; Antonarakis, S.E.; Brown, S.A.2017eLife1.1.
The Immune Signaling Adaptor LAT Contributes to the Neuroanatomical Phenotype of 16p11.2 BP2-BP3 CNVsLoviglio, M.N.; Arbogast, T.; Jønch, A.E.; Collins, S.C.; Popadin, K.; Bonnet, C.S.; Giannuzzi, G.; Maillard, A.M.; Jacquemont, S.; Loviglio, M.N.; Jønch, A.E.; Popadin, K.; Giannuzzi, G.; Maillard, A.M.; Fagerberg, C.; Andersen, C.B.; Doco-Fenzy, M.; Delrue, M.-A.; Faivre, L.; Arveiler, B. ... 2017American Journal of Human Genetics1.1.
Intra- and inter-chromosomal chromatin interactions mediate genetic effects on regulatory networksDelaneau, Olivier; Zazhytska, Marianna; Borel, Christelle; Howald, Cedric; Kumar, Sunil; Ongen, Halit; Popadin, Konstantin; Marbach, Daniel; Ambrosini, Giovanna; Bielser, Deborah; Hacker, David; Romano-Palumbo, Luciana; Ribaux, Pascal; Wiederkehr, Michael; Falconnet, Emilie; Bucher, Philipp; Bergmann, Sven; Antonarakis, Stylianos; Reymond, Alexandre; Dermitzakis, Emmanouil2017Intra- and inter-chromosomal chromatin interactions mediate genetic effects on regulatory networks6.7.
Integration of mtDNA pseudogenes into the nuclear genome coincides with speciation of the human genus. A hypothesisGunbin, K.; Peshkin, L.; Popadin, K.; Annis, S.; Ackermann, R.R.; Khrapko, K.;2017Mitochondrion6.8.
Amelioration of premature aging in mtDNA mutator mouse by exercise: the interplay of oxidative stress, PGC-1α, p53, and DNA damage. A hypothesisSafdar, A.; Annis, S.; Kraytsberg, Y.; Laverack, C.; Saleem, A.; Popadin, K.; Woods, D.C.; Tilly, J.L.; Khrapko, K.;2016Current Opinion in Genetics and Development1.1.
APOBEC-induced mutations in human cancers are strongly enriched on the lagging DNA strand during replicationSeplyarskiy, V.B.; Soldatov, R.A.; Popadin, K.Y.; Antonarakis, S.E.; Bazykin, G.A.; Nikolaev, S.I.2016Genome Research1.1.
Genomic analysis identifies new drivers and progression pathways in skin basal cell carcinomaBonilla, X.; Parmentier, L.; King, B.; Bezrukov, F.; Kaya, G.; Zoete, V.; Seplyarskiy, V.B.; Sharpe, H.J.; McKee, T.; Letourneau, A.; Ribaux, P.G.; Popadin, K.; Basset-Seguin, N.; Chaabene, R.B.; Santoni, F.A.; Andrianova, M.A.; Guipponi, M.; Garieri, M.; Verdan, C.; Grosdemange, K. ... 2016Nature Genetics1.1.
A genetic component of extinction risk in mammalsPolishchuk, L.V.; Popadin, K.Y.; Baranova, M.A.; Kondrashov, A.S.2015Oikos1.1.
Biased allelic expression in human primary fibroblast single cellsBorel, C.; Ferreira, P.G.; Santoni, F.; Delaneau, O.; Fort, A.; Popadin, K.Y.; Garieri, M.; Falconnet, E.; Ribaux, P.; Guipponi, M.; Padioleau, I.; Carninci, P.; Dermitzakis, E.T.; Antonarakis, S.E.;2015American Journal of Human Genetics1.1.
DNA-methylation patterns in trisomy 21 using cells from monozygotic twinsSailani, M.R.; Santoni, F.A.; Letourneau, A.; Borel, C.; Makrythanasis, P.; Hibaoui, Y.; Popadin, K.; Bonilla, X.; Guipponi, M.; Gehrig, C.; Vannier, A.; Carre-Pigeon, F.; Feki, A.; Nizetic, D.; Antonarakis, S.E.2015 PLoS ONE1.1.
Domains of genome-wide gene expression dysregulation in Down's syndromeLetourneau, A.; Santoni, F.A.; Bonilla, X.; Sailani, M.R.; Gonzalez, D.; Kind, J.; Chevalier, C.; Thurman, R.; Sandstrom, R.S.; Hibaoui, Y.; Garieri, M.; Popadin, K.; Falconnet, E.; Gagnebin, M.; Gehrig, C.; Vannier, A.; Guipponi, M.; Farinelli, L.; Robyr, D.; Migliavacca, E. ... Antonarakis, S.E.2014Nature1.1.
Gene age predicts the strength of purifying selection acting on gene expression variation in humansPopadin, K.Y.; Gutierrez-Arcelus, M.; Lappalainen, T.; Buil, A.; Steinberg, J.; Nikolaev, S.I.; Lukowski, S.W.; Bazykin, G.A.; Seplyarskiy, V.B.; Ioannidis, P.; Zdobnov, E.M.; Dermitzakis, E.T.; Antonarakis, S.E.2014American Journal of Human Genetics1.1.
Mitochondrial DNA mutations and cancer: Lessons from the parathyroidPopadin, K.; Gunbin, K.V.; Khrapko, K.;2014American Journal of Pathology6.8.
When man got his mtDNA deletions?Popadin, K.; Safdar, A.; Kraytsberg, Y.; Khrapko, K.;2014Aging Cell6.8.
Genetic and epigenetic regulation of human lincrna gene expressionPopadin, K.; Gutierrez-Arcelus, M.; Dermitzakis, E.T.; Antonarakis, S.E.2013American Journal of Human Genetics1.1.
Purifying selection in mammalian mitochondrial protein-coding genes is highly effective and congruent with evolution of nuclear genesPopadin, K.Y.; Nikolaev, S.I.; Junier, T.; Baranova, M.; Antonarakis, S.E.2013Molecular Biology and Evolution1.1.
Roles of mitochondrial dynamics under stressful and normal conditions in yeast cellsKnorre, D.A.; Popadin, K.Y.; Sokolov, S.S.; Severin, F.F.;2013Oxidative Medicine and Cellular Longevity1.1.
The complex SNP and CNV genetic architecture of the increased risk of congenital heart defects in Down syndromeSailani, M.R.; Makrythanasis, P.; Valsesia, A.; Santoni, F.A.; Deutsch, S.; Popadin, K.; Borel, C.; Migliavacca, E.; Sharp, A.J.; Sail, G.D.; Falconnet, E.; Rabionet, K.; Serra-Juhé, C.; Vicari, S.; Laux, D.; Grattau, Y.; Dembour, G.; Megarbane, A.; Touraine, R.; Stora, S. ... Antonarakis, S.E.2013Genome Research1.1.
Repeats, longevity and the sources of mtDNA deletions: Evidence from 'deletional spectra'Guo, X.; Popadin, K.Y.; Markuzon, N.; Orlov, Y.L.; Kraytsberg, Y.; Krishnan, K.J.; Zsurka, G.; Turnbull, D.M.; Kunz, W.S.; Khrapko, K.;2010Trends in Genetics6.8.