Kristina Anderson

https://www.etis.ee/CV/Kristina_Anderson/est
20.04.1963
+372426305
+4747172292
kristina.anderson@so-hf.no

Teenistuskäik

Töökohad ja ametid
08.09.2009–31.12.2013   
Tartu Ülikool, Arstiteaduskond, Hematoloogia-onkoloogia kliinik, hematoloogia vanemteadur (1,00)
2003–2003   
Tartu Ülikool, Erakorraline teadur (1,00)
1997–1999   
SA Tartu Ülikooli Kliinikum, arst-hematoloog (0,25)
1997–2001   
SA Tartu Ülikooli Kliinikum, arst-hematoloog (1,00)
1996–2000   
SA Tartu Ülikooli Kliinikum, arst (0,30)
1993–1997   
Tartu Ülikool, doktorant (1,00)
1991–1993   
SA Tartu Ülikooli Kliinikum, arst (0,50)
1988–1993   
SA Tartu Ülikooli Kliinikum, arst (1,00)
 
 
Haridustee
1980–1987   
Tartu Ülikool, arstiteaduskond
1970–1980   
Tartu 4 Keskkool

Kvalifikatsioon

Teaduskraadid
Kristina Anderson, doktorikraad, 2007, (juh) , Cellular pathways and molecular regulation of hematopoietic stem cells, Lund Universitetet.
Kristina Anderson, magistrikraad (teaduskraad), 2001, (juh) , Fluorescence In Situ Hybridization for the study of myelodysplastic syndromes with monosomy 7 and deletion 5q, Karolinska Institutet.
 
 

Lõppenud projektid

Juhendamisel väitekirjad

Publikatsioonid

Klass
Aasta
Publikatsioon
 
1.1.
2012
Luc, S.; Luis, TC.; Boukarabila, H.; Macaulay, IC.; Buza-Vidas, N.; Bouriez-Jones, T.; Lutteropp, M.; Woll, PS., Mead, AJ.; Hultquist, A.; Brown, J., Mizukami, T.; Matsuoka, S.; Ferry, H.; Anderson, K.; Duarte, S.; Atkinson, D.; Saneji, S.; Domanski, A.; Farley, A.; Sanjuan-Pla, A.; Carella, S. ... Jacobsen, SWE. (2012). The earliest thymic T cell progenitors sustain B cell and myeloid lineage potential. Nature immunology, 13 (4), 412−419.10.1038/ni.2255.
1.1.
2011
van Delft, Frederic; Horsley, Sharon; Colman, Susan; Anderson, Kristina; Bateman, Caroline; Kempski, Helena; Zuna, Jan; Eckert, Cornelia; Saha, Vaskar; Kearney, Lyndal; Ford, Anthony; Greaves, Mel. (2011). Clonal origins of relapse in ETV6-RUNX1 acute lymphoblastic leukemia. Blood, 117 (23), 6247−6254.
1.1.
2011
Anderson, Kristina; Lutz, Christoph; Van Delft, Frederik; Bateman, Caroline; Guo, Yanping; Colman, Susan; Kempski, Helena; Moorman, Anthony; Titley, Ian; Swansbury, John; Kearney, Lyndal; Enver, Tariq; Greaves, Mel. (2011). Genetic variegation of clonal architecture and stem cells in leukemia. Nature, 469 (469), 356−361.
1.1.
2010
Tehranchi, R.; Woll, PS.; Anderson, K.; Buza-Vidas, N.; Mizukami, T.; Mead, AJ.; Åstrand-Grundström, I.; Strömbeck, B.; Horvat, A.; Ferry, H.; Singh Dhanda, R.; Hast, R.; Rydén, T.; Vyas, P.; Göhring, G.; Schlegelberger, B.; Johansson, B.; Hellström-Lindberg, E.; List, A.; Nilsson, L. ... and Jacobsen, SEW (2010). Persistent malignant stem cells in del(5q) myelodysplasia in remission. New England Journal of Medicine, 363, 1025−1037.10.1056/NEJMoa0912228.
1.1.
2009
Kearney, L; Gonzales-di Castro, D; Yeung, Y; Procter, J; Horsley, SW; Eguchi-Ishimae, M; Bateman, CM; Anderson, K; Chaplin, T; Harrison, CJ; Kempski, H; So, CWE, Ford, AM; Greaves, M (2009). A specific JAK2 mutation (< I >JAK2< /I >R683) and multiple gene deletions in Down's syndrome acute lymphoblastic leukemia. Blood, 113 (3), 646−648.10.1182/blood-2008-08-170928.
1.1.
2008
Mansson, R; Zandi, S; Anderson, K; Martensson, IL; Jacobsen, SWE; Sigvardsson, M. (2008). B-lineage commitment prior to surface expression of B220 and CD19 on hematopoietic stem cells. Blood, 112, 4, 1048−1055.
1.1.
2008
Luc, S; Anderson, K; Kharazi, S; buza-Vidas, N; boiers, C; Jensen, CT; Ma, Z; Wittmann, L; Jacobsen, SWE (2008). Down-regulation of Mpl marks the transition to lymphoid-primed multipotent progenitors with gradual loss of granulocyte-monocyte potential. Blood, 111 (7), 3424−3434.
1.1.
2007
Lee, BH.; Tothova, Z.; Levine, RL.; Anderson, K.; Buza-Vidas, N.; Cullen, DE.; McDowell, EP.; Adelsperger, J.; Huntly, BJP.; Beran, M.; Jacobsen, SWE.; Gilliland, DG. (2007). Leukemogenic FLT3 mutations confer enhanced proliferation and survival properties to hematopoietic stem cells in a murine model of chronic myeloid leukemia. Cancer Cell, 12 (4), 367−380.10.1016/j.ccr.2007.08.031.
1.1.
2007
Nilsson, L; Eden, P; Olsson, E; Mansson, R; Astrand-Grundstrom, I; Strombeck, B; Thielgaard-Moench, K; Anderson, K; Hast, R; Hellstrom-Lindberg, E; Samuelsson, J; Bergh, G; Johansson, B; Sigvardsson, M; Borg, A; Jacobsen, SWE (2007). The molecular signature of cancer stem cells reveals a stem cell origin of 5q- myelodysplastic syndrome. Blood, 110 (8), 3005−3014.10.1182/blood-2007-03-079368.
1.1.
2007
Mansson, R; Hultquist, A; Luc, S; Yang, L; Anderson, K; Kharazi, S; Al-Hashmi, S; Liuba, K; Thoren, LAM; Adolfsson, J; buza-Vidas, N; Qian, H; Soneji, S; Enver, T, Sigvardsson, M; Jacobsen, SWE (2007). Molecular evidence for Hierarchical Transcriptional lineage priming in fetal and adult stem cells and multipotent projenitors. Immunity, 26 (4), 407−419.10.1016/j.immuni.2007.02.013.
1.1.
2007
Fujimoto, T; Anderson, K; Jacobsen, SWE; Nishikawa, SI; Nerlov, C (2007). Cdk6 blocs myeloid differentiation by interfering with Runx1 DNA binding and Runx1-CEBPalpha interaction. EMBO Journal, 26 (9), 2361−2370.10.1038/sj.emboj.7601675.
1.1.
2007
Anderson, K; Rusterholz, CMansson, R, Jensen CT, Bacos, K; Sasaki, Y; Nerlov, C, Sigvardsson, M; Jacobsen, SWE (2007). Ectopic expression of PAX5 promotes self-renewal of bi-phenotypic myeloid progenitors co-expressing myeloid and B-cell lineage associated genes. Blood, 109 (9), 3697−3705.
1.1.
2006
Kirstetter, P; Anderson, K; Porse, B; Jacobsen, SWE; Nerlov, C (2006). Activation of canonical Wnt pathway leads to loss of hematopoietic stem cell repopulation and multilineage differentiation block. Nature Genetics, 7 (10), 1−9.10.1038/ni1381.
1.1.
2006
Buza-Vidas, N; Antonchuk, J; Qian, H; Mansson, R; Luc, S; Zandi, S; Anderson, K; Takaki, S; Nygren, J; Jensen, CT; Jacobsen, S. (2006). Cytokines regulate postnatal hematopoietic stem cell expansion: opposing roles of thrombopoietin and LNK. Genes and Development, 20 (15), 2018−2023.
1.1.
2005
Adolfsson, J; Mansson, R; Buza-Vidas, N; Hultquist, A; Liuba, K; Jensen, CT; Bryder, D; Yang, L; Borge, OJ; Thoren, LAM; Anderson, K; Sitnicka, E; Sasaki, Y; Sigvardsson, M; Jacobsen, SWE (2005). Identification of Flt3+ lympho-myeloid stem cells lacking erythro-megakaryocytic potential: a revised road map for adult blood lineage commitment. Cell, 121 (2), 295−306.
1.1.
2005
Castor, A; Nilsson, L; Astrand-Grundstrom, I; Buitenhuis, M; Ramirez, C; Anderson, K; Strombeck, B; Garwicz, S; Becassy, AN; Schmiegelow, K; Lausen, B; Hokland, P; Lehmann, S; uliusson, G; Johansson, B; Jacobsen, SWE (2005). Distinct patterns of hematopoietic stem cell involvement in acute lymphoblastic leukemia. Nature Medicine, 11 (6), 630−607.
1.1.
2005
Porse, BT; Bryder, D; Theilgaard-Monch, K; Hasemann, MS; Anderson, K; Damgaard, I; Jacobsen, SWE; Nerlov, C. (2005). Loss of CEBP alpha cell cycle control increases myeloid progenitor prolipheration and transforms the neutrophil granulocyte lineage. Journal of Experimental Medicine, 202 (1), 85−96.
1.1.
2002
Anderson, K; Arvidsson, I; Jacobsson, B; Hast, R. (2002). Fluorescence in situ hybridization (FISH) for the study of cell lineage involvement in myelodysplastic syndromes with chromosome 5 anomalies. Cancer Genetics and Cytogenetics, 136 (1), 101−107.
1.2.
2002
Nilsson, L; Astrand-Grundstrom, I; Anderson, K; Arvidsson, I; Hokland, P; Bryder, D; Kjeldsen, L; Johansson, B; Hellstrom-Lindberg, E; Hast, R; Jacobsen, SWE. (2002). Involvement and functional impairment of the CD34+CD38-Thy-1+ hematopoietic stem cell pool in myelodysplastic syndromes with chromosome 5 abnormalities. Blood, 100 (1), 259−267.
1.1.
2001
Jakovleva, K.; Arvidsson, I.; Jacobsson, B.; Swolin, B.; Hast, R. (2001). Masked monosomy 7 in myelodysplastic syndromes is uncommon and of undetermined clinical significance. Leukemia Research, 25 (3), 197−203.
1.1.
1998
Jakovleva, K.; Everaus, H. (1998). Some aspects of morphological and dysplastic changes of the bone marrow in malignant lymphoma. Acta Haematologica, 100 (3), 142−146.
1.2.
1998
Hast, R.; Eriksson, M.; Jakovleva, K. (1998). Aspects on the clinical use of hematopoietic growth factors in myelodysplastic syndromes. Pol Arch Med Wewn., 99 (2), 144−149.
1.3.
1997
Luik, E.; Jakovleva, K.; Everaus, H. (1997). Kasuistikast hematoloogias. Eesti Arst, 1, 66−68.
1.3.
1996
Jakovleva, K.; Everaus, H. (1996). Müelodüsplastilised sündroomid. Eesti Arst, 2, 147−152.
18.04.2019

Kristina Anderson

https://www.etis.ee/CV/Kristina_Anderson/eng
20.04.1963
+372426305
+4747172292
kristina.anderson@so-hf.no

Career

Institution(s) and position(s)
08.09.2009–31.12.2013   
University of Tartu, Faculty of Medicine, Department of Haematology and Oncology, Senior Research Fellow in Hematology (1,00)
2003–2003   
University of Tartu, Extraordinary Researcher (1,00)
1997–1999   
Tartu University Hospital, Other staff (0,25)
1997–2001   
Tartu University Hospital, Other staff (1,00)
1996–2000   
Tartu University Hospital, Other staff (0,30)
1993–1997   
University of Tartu, Other staff (1,00)
1991–1993   
Tartu University Hospital, Other staff (0,50)
1988–1993   
Tartu University Hospital, Other staff (1,00)
 
 
Education
1980–1987   
1970–1980   

Qualifications

Academic degrees
Kristina Anderson, Doctor's Degree, 2007, (sup) , Cellular pathways and molecular regulation of hematopoietic stem cells, Lund Universitetet.
Kristina Anderson, Research Master's Degree, 2001, (sup) , Fluorescence In Situ Hybridization for the study of myelodysplastic syndromes with monosomy 7 and deletion 5q, Karolinska Institutet.
 
 

Completed projects

Dissertations under supervision

Publications

Category
Year
Publication
 
1.1.
2012
Luc, S.; Luis, TC.; Boukarabila, H.; Macaulay, IC.; Buza-Vidas, N.; Bouriez-Jones, T.; Lutteropp, M.; Woll, PS., Mead, AJ.; Hultquist, A.; Brown, J., Mizukami, T.; Matsuoka, S.; Ferry, H.; Anderson, K.; Duarte, S.; Atkinson, D.; Saneji, S.; Domanski, A.; Farley, A.; Sanjuan-Pla, A.; Carella, S. ... Jacobsen, SWE. (2012). The earliest thymic T cell progenitors sustain B cell and myeloid lineage potential. Nature immunology, 13 (4), 412−419.10.1038/ni.2255.
1.1.
2011
van Delft, Frederic; Horsley, Sharon; Colman, Susan; Anderson, Kristina; Bateman, Caroline; Kempski, Helena; Zuna, Jan; Eckert, Cornelia; Saha, Vaskar; Kearney, Lyndal; Ford, Anthony; Greaves, Mel. (2011). Clonal origins of relapse in ETV6-RUNX1 acute lymphoblastic leukemia. Blood, 117 (23), 6247−6254.
1.1.
2011
Anderson, Kristina; Lutz, Christoph; Van Delft, Frederik; Bateman, Caroline; Guo, Yanping; Colman, Susan; Kempski, Helena; Moorman, Anthony; Titley, Ian; Swansbury, John; Kearney, Lyndal; Enver, Tariq; Greaves, Mel. (2011). Genetic variegation of clonal architecture and stem cells in leukemia. Nature, 469 (469), 356−361.
1.1.
2010
Tehranchi, R.; Woll, PS.; Anderson, K.; Buza-Vidas, N.; Mizukami, T.; Mead, AJ.; Åstrand-Grundström, I.; Strömbeck, B.; Horvat, A.; Ferry, H.; Singh Dhanda, R.; Hast, R.; Rydén, T.; Vyas, P.; Göhring, G.; Schlegelberger, B.; Johansson, B.; Hellström-Lindberg, E.; List, A.; Nilsson, L. ... and Jacobsen, SEW (2010). Persistent malignant stem cells in del(5q) myelodysplasia in remission. New England Journal of Medicine, 363, 1025−1037.10.1056/NEJMoa0912228.
1.1.
2009
Kearney, L; Gonzales-di Castro, D; Yeung, Y; Procter, J; Horsley, SW; Eguchi-Ishimae, M; Bateman, CM; Anderson, K; Chaplin, T; Harrison, CJ; Kempski, H; So, CWE, Ford, AM; Greaves, M (2009). A specific JAK2 mutation (< I >JAK2< /I >R683) and multiple gene deletions in Down's syndrome acute lymphoblastic leukemia. Blood, 113 (3), 646−648.10.1182/blood-2008-08-170928.
1.1.
2008
Mansson, R; Zandi, S; Anderson, K; Martensson, IL; Jacobsen, SWE; Sigvardsson, M. (2008). B-lineage commitment prior to surface expression of B220 and CD19 on hematopoietic stem cells. Blood, 112, 4, 1048−1055.
1.1.
2008
Luc, S; Anderson, K; Kharazi, S; buza-Vidas, N; boiers, C; Jensen, CT; Ma, Z; Wittmann, L; Jacobsen, SWE (2008). Down-regulation of Mpl marks the transition to lymphoid-primed multipotent progenitors with gradual loss of granulocyte-monocyte potential. Blood, 111 (7), 3424−3434.
1.1.
2007
Lee, BH.; Tothova, Z.; Levine, RL.; Anderson, K.; Buza-Vidas, N.; Cullen, DE.; McDowell, EP.; Adelsperger, J.; Huntly, BJP.; Beran, M.; Jacobsen, SWE.; Gilliland, DG. (2007). Leukemogenic FLT3 mutations confer enhanced proliferation and survival properties to hematopoietic stem cells in a murine model of chronic myeloid leukemia. Cancer Cell, 12 (4), 367−380.10.1016/j.ccr.2007.08.031.
1.1.
2007
Nilsson, L; Eden, P; Olsson, E; Mansson, R; Astrand-Grundstrom, I; Strombeck, B; Thielgaard-Moench, K; Anderson, K; Hast, R; Hellstrom-Lindberg, E; Samuelsson, J; Bergh, G; Johansson, B; Sigvardsson, M; Borg, A; Jacobsen, SWE (2007). The molecular signature of cancer stem cells reveals a stem cell origin of 5q- myelodysplastic syndrome. Blood, 110 (8), 3005−3014.10.1182/blood-2007-03-079368.
1.1.
2007
Mansson, R; Hultquist, A; Luc, S; Yang, L; Anderson, K; Kharazi, S; Al-Hashmi, S; Liuba, K; Thoren, LAM; Adolfsson, J; buza-Vidas, N; Qian, H; Soneji, S; Enver, T, Sigvardsson, M; Jacobsen, SWE (2007). Molecular evidence for Hierarchical Transcriptional lineage priming in fetal and adult stem cells and multipotent projenitors. Immunity, 26 (4), 407−419.10.1016/j.immuni.2007.02.013.
1.1.
2007
Fujimoto, T; Anderson, K; Jacobsen, SWE; Nishikawa, SI; Nerlov, C (2007). Cdk6 blocs myeloid differentiation by interfering with Runx1 DNA binding and Runx1-CEBPalpha interaction. EMBO Journal, 26 (9), 2361−2370.10.1038/sj.emboj.7601675.
1.1.
2007
Anderson, K; Rusterholz, CMansson, R, Jensen CT, Bacos, K; Sasaki, Y; Nerlov, C, Sigvardsson, M; Jacobsen, SWE (2007). Ectopic expression of PAX5 promotes self-renewal of bi-phenotypic myeloid progenitors co-expressing myeloid and B-cell lineage associated genes. Blood, 109 (9), 3697−3705.
1.1.
2006
Kirstetter, P; Anderson, K; Porse, B; Jacobsen, SWE; Nerlov, C (2006). Activation of canonical Wnt pathway leads to loss of hematopoietic stem cell repopulation and multilineage differentiation block. Nature Genetics, 7 (10), 1−9.10.1038/ni1381.
1.1.
2006
Buza-Vidas, N; Antonchuk, J; Qian, H; Mansson, R; Luc, S; Zandi, S; Anderson, K; Takaki, S; Nygren, J; Jensen, CT; Jacobsen, S. (2006). Cytokines regulate postnatal hematopoietic stem cell expansion: opposing roles of thrombopoietin and LNK. Genes and Development, 20 (15), 2018−2023.
1.1.
2005
Adolfsson, J; Mansson, R; Buza-Vidas, N; Hultquist, A; Liuba, K; Jensen, CT; Bryder, D; Yang, L; Borge, OJ; Thoren, LAM; Anderson, K; Sitnicka, E; Sasaki, Y; Sigvardsson, M; Jacobsen, SWE (2005). Identification of Flt3+ lympho-myeloid stem cells lacking erythro-megakaryocytic potential: a revised road map for adult blood lineage commitment. Cell, 121 (2), 295−306.
1.1.
2005
Castor, A; Nilsson, L; Astrand-Grundstrom, I; Buitenhuis, M; Ramirez, C; Anderson, K; Strombeck, B; Garwicz, S; Becassy, AN; Schmiegelow, K; Lausen, B; Hokland, P; Lehmann, S; uliusson, G; Johansson, B; Jacobsen, SWE (2005). Distinct patterns of hematopoietic stem cell involvement in acute lymphoblastic leukemia. Nature Medicine, 11 (6), 630−607.
1.1.
2005
Porse, BT; Bryder, D; Theilgaard-Monch, K; Hasemann, MS; Anderson, K; Damgaard, I; Jacobsen, SWE; Nerlov, C. (2005). Loss of CEBP alpha cell cycle control increases myeloid progenitor prolipheration and transforms the neutrophil granulocyte lineage. Journal of Experimental Medicine, 202 (1), 85−96.
1.1.
2002
Anderson, K; Arvidsson, I; Jacobsson, B; Hast, R. (2002). Fluorescence in situ hybridization (FISH) for the study of cell lineage involvement in myelodysplastic syndromes with chromosome 5 anomalies. Cancer Genetics and Cytogenetics, 136 (1), 101−107.
1.2.
2002
Nilsson, L; Astrand-Grundstrom, I; Anderson, K; Arvidsson, I; Hokland, P; Bryder, D; Kjeldsen, L; Johansson, B; Hellstrom-Lindberg, E; Hast, R; Jacobsen, SWE. (2002). Involvement and functional impairment of the CD34+CD38-Thy-1+ hematopoietic stem cell pool in myelodysplastic syndromes with chromosome 5 abnormalities. Blood, 100 (1), 259−267.
1.1.
2001
Jakovleva, K.; Arvidsson, I.; Jacobsson, B.; Swolin, B.; Hast, R. (2001). Masked monosomy 7 in myelodysplastic syndromes is uncommon and of undetermined clinical significance. Leukemia Research, 25 (3), 197−203.
1.1.
1998
Jakovleva, K.; Everaus, H. (1998). Some aspects of morphological and dysplastic changes of the bone marrow in malignant lymphoma. Acta Haematologica, 100 (3), 142−146.
1.2.
1998
Hast, R.; Eriksson, M.; Jakovleva, K. (1998). Aspects on the clinical use of hematopoietic growth factors in myelodysplastic syndromes. Pol Arch Med Wewn., 99 (2), 144−149.
1.3.
1997
Luik, E.; Jakovleva, K.; Everaus, H. (1997). Kasuistikast hematoloogias. Eesti Arst, 1, 66−68.
1.3.
1996
Jakovleva, K.; Everaus, H. (1996). Müelodüsplastilised sündroomid. Eesti Arst, 2, 147−152.
18.04.2019
Detailne otsing
  • Leitud 2 kirjet
ProgrammLiikNumberNimiProjekti algusProjekti lõppVastutav täitjaAsutusFinantseerijapoolne rahastamine
SFSF0180161s08Kasvajaliste haiguste märklaudravi - peremeesorganismi mõjutamise võimalused01.01.200831.12.2012Hele EverausTartu Ülikool, Arstiteaduskond493 196,03 EUR
ETFETF8671Leukeemiliste tüvirakkude roll ägedate ja krooniliste leukeemiate ravi efektiivsuse aspektist01.01.201131.12.2015Kristina AndersonTartu Ülikool, Arstiteaduskond40 800,00 EUR