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Olen nõus

Lorena Simon Gracia

https://www.etis.ee/CV/Lorena_Simon Gracia/est
29.10.1982
737 4268
lorena.simon.gracia@ut.ee

Teenistuskäik

Töökohad ja ametid
16.09.2019–...   
Tartu Ülikool, Meditsiiniteaduste valdkond, bio- ja siirdemeditsiini instituut, vähibioloogia vanemteadur (1,00)
01.01.2016–...   
Tartu Ülikool, Meditsiiniteaduste valdkond, bio- ja siirdemeditsiini instituut, vähibioloogia teadur (1,00)
01.07.2018–15.09.2019   
Tartu Ülikool, Meditsiiniteaduste valdkond, bio- ja siirdemeditsiini instituut, vähibioloogia teadur (1,00)
02.01.2018–30.06.2018   
NCI Designated Cancer Center Sanford Burnham Prebys Medical Discovery Institute, La Jolla, USA, Post-doctoral Visit (1,00)
01.01.2018–30.06.2018   
Tartu Ülikool, Meditsiiniteaduste valdkond, bio- ja siirdemeditsiini instituut, vähibioloogia teadur (0,25)
01.07.2017–15.09.2017   
Department of Chemistry, University College London, UK. Molecular Bionic Labs, Külalisteadur (1,00)
07.01.2017–30.03.2017   
CIC biomaGUNE, San Sebastian, Spain. Soft Matter Nanotechnology Lab, Külalisteadur (1,00)
01.09.2015–31.12.2015   
Tartu Ülikool, Arstiteaduskond, Biomeditsiini instituut, vähibioloogia teadur (1,00)
01.11.2014–23.12.2014   
Department of Chemistry and Biochemistry. University of California San Diego, California, USA, Külalisteadur (0,50)
01.11.2014–23.12.2014   
NCI Designated Cancer Center Sanford Burnham Prebys Medical Discovery Institute, La Jolla, USA, Külalisteadur (0,50)
21.05.2013–31.08.2015   
Tartu Ülikool, Arstiteaduskond, Biomeditsiini instituut, teadur (1,00)
01.10.2012–20.05.2013   
Tartu Ülikool, Arstiteaduskond, Üld- ja molekulaarpatoloogia instituut, teadur (1,00)
01.09.2012–30.09.2012   
Tartu Ülikool, Arstiteaduskond, Üld- ja molekulaarpatoloogia instituut, teadur (1,00)
01.01.2011–01.08.2012   
Institute for Research in Biomedicine, University of Barcelona, Teadur (1,00)
01.03.2010–01.07.2010   
Department of Chemistry, University of Sheffield, Doctoral Stay abroad (1,00)
 
 
Haridustee
2007–30.09.2011   
PhD at the University of Barcelona
15.09.2004–15.09.2008   
Bachelor Degree in Biochemistry
15.09.2000–20.07.2005   
Bachelor Degree in Chemistry
 
 
Lisainfo
Conference "Frontiers in Delivery of Therapeutics". August 2018, Tartu, Estonia;
Spring workshop in Tartu: "Targeting nanosystems for imaging and therapy". May 2017, Tartu, Estonia. Organizer of the workshop;
Gordon Research Seminars: Drug Carriers in Medicine & Biology. August 2016. New Hampshire, USA. Invited speaker for oral presentation. “pH-sensitive polymersomes targeted with CendR peptides for treatment of peritoneal carcinomatosis”;
Gordon Research Conference: Drug Carriers in Medicine & Biology. August 2016. New Hampshire, USA. Poster presentation. “pH-sensitive polymersomes targeted with CendR peptides for treatment of peritoneal carcinomatosis”;
11th International Symposium on Polymer Therapeutics: From Laboratory to Clinical Practice. May 2016. Valencia, Spain. Oral presentation. “pH-sensitive polymersomes targeted with CendR peptides for treatment of peritoneal carcinomatosis”;
NanoBioMed. Nanobiologia y Nanomedicina. November 2015. Barcelona, Spain. Oral presentation. “Tumor penetrating polymersomes for cancer theranostics”;
EMN Cancun Meeting. Energy Materials Nanotechnology. June 2015. Cancun, Mexico. Oral presentation: “Tumor penetrating pH-sensitive polymersomes for intraperitoneal tumor theranostics” ;
The European Summit for Clinical Nanomedicine and Targeted Medicine. “Paving the way to personalized diagnostics and therapy”. CLINAM (European Foundation for Clinical Nanomedicine). June 2014, Basel, Switzerland. Poster presentation: “Tumor penetrating pH-sensitive polymersomes for cancer theranostics”;
Special Symposium of the Finish Peptide Society. December 2013, Helsinki. Plenary lecture: “Peptide-mediated targeted drug delivery systems for cancer therapy” ;

Kvalifikatsioon

Teaduskraadid
Lorena Simon Gracia, doktorikraad, 2011, (juh) Fernando Albericio; Miriam Royo, Desarrollo de nanoconjugados como transportadores de fármacos anticancerígenos: dendrímeros multifuncionales basados en polietilenglicol y polimersomas del copolímero PMPC-PDPA, Universitat de Barcelona.
 
 
Teaduspreemiad ja tunnustused
2017, Lorena Simon Gracia, Post-doctoral fellowship Mobilitas Plus (MOBJD11) Institution: Estonian Government
2014, Lorena Simon Gracia, Swiss funded SCOPES Programme of the Swiss National Foundation. Fellowship for the assistance of The European Summit for Clinical Nanomedicine and Targeted Medicine (CLINAM). Switzerland, June 2014.
2010, Lorena Simon Gracia, PhD Fellowship for foreign stays (BE-DGR 2010-Grant for research in a foreign country) Institution: Catalan Government (Generalitat de Catalunya)
2007, Lorena Simon Gracia, PhD Fellowship (FI-DGR 2007-Investigator formation) Institution: Catalan Government (Generalitat de Catalunya)
 
 
Teadustöö põhisuunad
ETIS KLASSIFIKAATOR: 4. Loodusteadused ja tehnika; 4.11. Keemia ja keemiatehnika; CERCS KLASSIFIKAATOR: P390 Orgaaniline keemia

Jooksvad projektid

Lõppenud projektid

Publikatsioonid

Klass
Aasta
Publikatsioon
 
1.1.
2019
Asciutto, Eliana K; Kopanchuk, Sergei; Lepland, Anni; Simón-Gracia, Lorena; Aleman, Carlos; Teesalu, Tambet; Scodeller, Pablo (2019). Phage-Display-Derived Peptide Binds to Human CD206 and Modeling Reveals a New Binding Site on the Receptor. The Journal of Physical Chemistry. B, 123 (9), 1973−1982.10.1021/acs.jpcb.8b11876.
1.1.
2019
Säälik, Pille; Lingasamy, Prakash; Toome, Kadri; Mastandrea, Ignacio; Rousso-Noori, Liat; Tobi, Allan; Simón-Gracia, Lorena; Hunt, Hedi; Paiste, Päärn; Kotamraju, Venkata Ramana; Bergers, Gabriele; Asser, Toomas; Rätsep, Tõnu; Ruoslahti, Erkki; Bjerkvig, Rolf; Friedmann-Morvinski, Dinorah; Teesalu, Tambet (2019). Peptide-guided nanoparticles for glioblastoma targeting. Journal of controlled release : official journal of the Controlled Release Society, 308, 109−118.10.1016/j.jconrel.2019.06.018.
1.1.
2018
Emily Wonder, Lorena Simón-Gracia, Pablo Scodeller, Ramsey N. Majzoub, Venkata Ramana Kotamraju, Kai K. Ewert, Tambet Teesalu, Cyrus R. Safinya (2018). Competition of charge-mediated and specific binding by peptide-tagged cationic liposome–DNA nanoparticles in vitro and in vivo. Biomaterials, 166, 52−63.10.1016/j.biomaterials.2018.02.052.
1.1.
2018
Simón-Gracia, Lorena; Scodeller, Pablo; Salazar Fuentes, Sergio; Gómez Vallejo, Vanessa; Ríos, Xabier; San Sebastián, Eneko; Sidorenko, Valeria; Di Silvio, Desirè; Suck, Meina; De Lorenzi, Federica; Yokota Rizzo, Larissa; von Stillfried, Saskia; Kilk, Kalle; Lammers, Twan; Moya, Sergio E.; Teesalu, Tambet (2018). Application of polymersomes engineered to target p32 protein for detection of small breast tumors in mice. Oncotarget, 9 (27), 18682−18697.10.18632/oncotarget.24588.
1.1.
2018
Simon-Gracia, Lorena; Hunt, Hedi; Teesalu, Tambet (2018). Peritoneal carcinomatosis targeting with tumor homing peptides. Macromolecules, 23, 1190.10.3390/molecules23051190.
1.1.
2017
Hideki Ikemoto, Prakash Lingasamy, Anne-Mari Anton Willmore, Hedi Hunt, Kaarel Kurm, Olav Tammik, Pablo Scodeller, Lorena Simón-Gracia, Venkata Ramana Kotamraju, Andrew M Lowy, Kazuki N Sugahara, Tambet Teesalu (2017). Hyaluronan-binding peptide for targeting peritoneal carcinomatosis. Tumor Biology, 39 (5), 1−9.10.1177/1010428317701628.
1.1.
2017
Ikemoto, Hideki; Lingasamy, Prakash; Anton Willmore, Anne-Mari; Hunt, Hedi; Kurm, Kaarel; Tammik, Olav; Scodeller, Pablo; Simón-Gracia, Lorena; Kotamraju, Venkata Ramana; Lowy, Andrew M; Sugahara, Kazuki N; Teesalu, Tambet (2017). Hyaluronan-binding peptide for targeting peritoneal carcinomatosis. Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine, 39 (5), 1−9.10.1177/1010428317701628.
1.1.
2017
Scodeller, Pablo; Simón-Gracia, Lorena; Kopanchuk, Sergei; Tobi, Allan; Kilk, Kalle; Säälik, Pille; Kurm, Kaarel; Squadrito, Mario Leonardo; Kotamraju, Venkata Ramana; Rinken, Ago; De Palma, Michele; Ruoslahti, Erkki; Teesalu, Tambet (2017). Precision Targeting of Tumor Macrophages with a CD206 Binding Peptide. Scientific Reports, 7 (1), 14655−14655.10.1038/s41598-017-14709-x.
1.1.
2017
Hunt, H.; Simón-Gracia, L.; Tobi, A.; Kotamraju, V.R.; Sharma, S.; Nigul, M.; Sugahara, K.N.; Ruoslahti, E.; Teesalu, T. (2017). Targeting of p32 in peritoneal carcinomatosis with intraperitoneal linTT1 peptide-guided pro-apoptotic nanoparticles. Journal of Controlled Release, 260 (260), 142−153.10.1016/j.jconrel.2017.06.005.
3.1.
2017
Rauwel, E.; Simón-Gracia, L.; Guha, M.; Rauwel, P.; Kuunal, S.; Wragg, D. (2017). Silver metal nanoparticles study for biomedical and green house applications. IOP Conference Series: Materials Science and Engineering, 175, 1−5.10.1088/1757-899X/175/1/012011.
1.1.
2016
Simon-Gracia, Lorena; Hunt, Hedi; Scodeller, Pablo D; Gaitzsch, Jens; Braun, Gary B; Willmore, Anne-Mari A; Ruoslahti, Erkki; Battaglia, Giuseppe; Teesalu, Tambet (2016). Paclitaxel-Loaded Polymersomes for Enhanced Intraperitoneal Chemotherapy. Molecular cancer therapeutics, 15, 670−679.10.1158/1535-7163.MCT-15-0713-T.
1.1.
2016
Willmore, Anne-Mari A.; Simon-Gracia, Lorena; Toome, Kadri; Paiste, Päärn; Kotamraju, Venkata Ramana; Mölder, Tarmo; Sugahara, Kazuki N.; Ruoslahti, Erkki; Braun, Gary B.; Teesalu, Tambet (2016). Targeted silver nanoparticles for ratiometric cell phenotyping. Nanoscale, 8 (17), 9096−9101.10.1039/c5nr07928d.
1.1.
2016
Simón-Gracia, Lorena; Hunt, Hedi; Scodeller, Pablo; Gaitzsch, Jens; Kotamraju, Ventaka R; Sugahara, Kazuki N; Tammik, Olav; Ruoslahti, Erkki; Battaglia, Giuseppe; Teesalu, Tambet (2016). iRGD peptide conjugation potentiates intraperitoneal tumor delivery of paclitaxel with polymersomes. Biomaterials, 104, 247−257.10.1016/j.biomaterials.2016.07.023.
1.1.
2015
Fransen, Peter; Pulido, Daniel; Simón-Gracia, Lorena; Candiota, Ana Paula; Arús, Carles; Albericio, Fernando; Royo, Miriam (2015). r1 and r2 relaxivities of dendrons based on a OEG-DTPA architecture: effect of Gd3+ placement and dendron functionalization. Journal of Nanotechnology, 2015, 848020.10.1155/2015/848020.
1.1.
2014
Simon Gracia, Lorena (2014). Liposomes containing NY‑ESO‑1/tetanus toxoid and adjuvant peptides targeted to human dendritic cells via the Fc receptor for cancer vaccines. Nanomedicine, 9 (4), 435−449.10.2217/nnm.13.66.
1.1.
2013
Simon Gracia, Lorena (2013). Enhanced drug delivery to melanoma cells using PMPC-PDPA polymersomes. Cancer Letters, 334 (2), 328−337.10.1016/j.canlet.2013.02.007.
1.1.
2013
Simón-Gracia, L.; Pulido, D.; Sevrin, C.; Grandfils, C.; Albericio, F.; Royo, M. (2013). Biocompatible, multifunctional, and well-defined OEG-based dendritic platforms for biomedical applications. Organic and Biomolecular Chemistry, 11 (24), 4109−4121.10.1039/c3ob40492g.
1.1.
2011
Simon Gracia, Lorena (2011). Targeting nanosystems to human DCs via Fc receptor as an effective strategy to deliver antigen for immunotherapy. Molecular Pharmaceutics, 8 (1), 104−116.10.1021/mp100178k.
4.03.2020

Lorena Simon Gracia

https://www.etis.ee/CV/Lorena_Simon Gracia/eng
29.10.1982
737 4268
lorena.simon.gracia@ut.ee

Career

Institutions and positions
16.09.2019–...   
University of Tartu, Faculty of Medicine, Institute of Biomedicine and Translational Medicine, Senior Research Fellow of Cancer Biology (1,00)
01.01.2016–...   
University of Tartu, Faculty of Medicine, Institute of Biomedicine and Translational Medicine, Research Fellow of Cancer Biology (1,00)
01.07.2018–15.09.2019   
University of Tartu, Faculty of Medicine, Institute of Biomedicine and Translational Medicine, Research Fellow of Cancer Biology (1,00)
02.01.2018–30.06.2018   
NCI Designated Cancer Center Sanford Burnham Prebys Medical Discovery Institute, La Jolla, USA, Post-doctoral Visit (1,00)
01.01.2018–30.06.2018   
University of Tartu, Faculty of Medicine, Institute of Biomedicine and Translational Medicine, Research Fellow of Cancer Biology (0,25)
01.07.2017–15.09.2017   
Department of Chemistry, University College London, UK. Molecular Bionic Labs, Visiting Researcher (1,00)
07.01.2017–30.03.2017   
CIC biomaGUNE, San Sebastian, Spain. Soft Matter Nanotechnology Lab, Visiting Researcher (1,00)
01.09.2015–31.12.2015   
University of Tartu, Faculty of Medicine, Institute of Biomedicine, Research Fellow of Cancer Biology (1,00)
01.11.2014–23.12.2014   
Department of Chemistry and Biochemistry. University of California San Diego, California, USA, Visiting Researcher (0,50)
01.11.2014–23.12.2014   
NCI Designated Cancer Center Sanford Burnham Prebys Medical Discovery Institute, La Jolla, USA, Visiting Researcher (0,50)
21.05.2013–31.08.2015   
University of Tartu, Faculty of Medicine, Institute of Biomedicine, Research Fellow (1,00)
01.10.2012–20.05.2013   
University of Tartu, Faculty of Medicine, Departement of General and Molecular Pathology, Research Fellow (1,00)
01.09.2012–30.09.2012   
University of Tartu, Faculty of Medicine, Departement of General and Molecular Pathology, Research Fellow (1,00)
01.01.2011–01.08.2012   
Institute for Research in Biomedicine, University of Barcelona, Researcher (1,00)
01.03.2010–01.07.2010   
Department of Chemistry, University of Sheffield, Doctoral Stay abroad (1,00)
 
 
Education
2007–30.09.2011   
PhD at the University of Barcelona
15.09.2004–15.09.2008   
Bachelor Degree in Biochemistry
15.09.2000–20.07.2005   
Bachelor Degree in Chemistry
 
 
Additional information
Conference "Frontiers in Delivery of Therapeutics". August 2018, Tartu, Estonia;
Spring workshop in Tartu: "Targeting nanosystems for imaging and therapy". May 2017, Tartu, Estonia. Organizer of the workshop;
Gordon Research Seminars: Drug Carriers in Medicine & Biology. August 2016. New Hampshire, USA. Invited speaker for oral presentation. “pH-sensitive polymersomes targeted with CendR peptides for treatment of peritoneal carcinomatosis”;
Gordon Research Conference: Drug Carriers in Medicine & Biology. August 2016. New Hampshire, USA. Poster presentation. “pH-sensitive polymersomes targeted with CendR peptides for treatment of peritoneal carcinomatosis”;
11th International Symposium on Polymer Therapeutics: From Laboratory to Clinical Practice. May 2016. Valencia, Spain. Oral presentation. “pH-sensitive polymersomes targeted with CendR peptides for treatment of peritoneal carcinomatosis”;
NanoBioMed. Nanobiologia y Nanomedicina. November 2015. Barcelona, Spain. Oral presentation. “Tumor penetrating polymersomes for cancer theranostics”;
EMN Cancun Meeting. Energy Materials Nanotechnology. June 2015. Cancun, Mexico. Oral presentation: “Tumor penetrating pH-sensitive polymersomes for intraperitoneal tumor theranostics” ;
The European Summit for Clinical Nanomedicine and Targeted Medicine. “Paving the way to personalized diagnostics and therapy”. CLINAM (European Foundation for Clinical Nanomedicine). June 2014, Basel, Switzerland. Poster presentation: “Tumor penetrating pH-sensitive polymersomes for cancer theranostics”;
Special Symposium of the Finish Peptide Society. December 2013, Helsinki. Plenary lecture: “Peptide-mediated targeted drug delivery systems for cancer therapy” ;

Qualifications

Academic degrees
Lorena Simon Gracia, Doctor's Degree, 2011, (sup) Fernando Albericio; Miriam Royo, Desarrollo de nanoconjugados como transportadores de fármacos anticancerígenos: dendrímeros multifuncionales basados en polietilenglicol y polimersomas del copolímero PMPC-PDPA (Nanoconjugates as anticancer drug delivery systems: PEG‐based dendrimers and PMPC‐PDPA polymersomes), University of Barcelona.
 
 
Honours & awards
2017, Lorena Simon Gracia, Post-doctoral fellowship Mobilitas Plus (MOBJD11) Institution: Estonian Government
2014, Lorena Simon Gracia, Swiss funded SCOPES Programme of the Swiss National Foundation. Fellowship for the assistance of The European Summit for Clinical Nanomedicine and Targeted Medicine (CLINAM). Switzerland, June 2014.
2010, Lorena Simon Gracia, PhD Fellowship for foreign stays (BE-DGR 2010-Grant for research in a foreign country) Institution: Catalan Government (Generalitat de Catalunya)
2007, Lorena Simon Gracia, PhD Fellowship (FI-DGR 2007-Investigator formation) Institution: Catalan Government (Generalitat de Catalunya)
 
 
Fields of research
ETIS CLASSIFICATION: 4. Natural Sciences and Engineering; 4.11. Chemistry and Chemical Technology; CERCS CLASSIFICATION: P390 Organic chemistry
 
 

Projects in progress

Completed projects

Publications

Category
Year
Publication
 
1.1.
2019
Asciutto, Eliana K; Kopanchuk, Sergei; Lepland, Anni; Simón-Gracia, Lorena; Aleman, Carlos; Teesalu, Tambet; Scodeller, Pablo (2019). Phage-Display-Derived Peptide Binds to Human CD206 and Modeling Reveals a New Binding Site on the Receptor. The Journal of Physical Chemistry. B, 123 (9), 1973−1982.10.1021/acs.jpcb.8b11876.
1.1.
2019
Säälik, Pille; Lingasamy, Prakash; Toome, Kadri; Mastandrea, Ignacio; Rousso-Noori, Liat; Tobi, Allan; Simón-Gracia, Lorena; Hunt, Hedi; Paiste, Päärn; Kotamraju, Venkata Ramana; Bergers, Gabriele; Asser, Toomas; Rätsep, Tõnu; Ruoslahti, Erkki; Bjerkvig, Rolf; Friedmann-Morvinski, Dinorah; Teesalu, Tambet (2019). Peptide-guided nanoparticles for glioblastoma targeting. Journal of controlled release : official journal of the Controlled Release Society, 308, 109−118.10.1016/j.jconrel.2019.06.018.
1.1.
2018
Emily Wonder, Lorena Simón-Gracia, Pablo Scodeller, Ramsey N. Majzoub, Venkata Ramana Kotamraju, Kai K. Ewert, Tambet Teesalu, Cyrus R. Safinya (2018). Competition of charge-mediated and specific binding by peptide-tagged cationic liposome–DNA nanoparticles in vitro and in vivo. Biomaterials, 166, 52−63.10.1016/j.biomaterials.2018.02.052.
1.1.
2018
Simón-Gracia, Lorena; Scodeller, Pablo; Salazar Fuentes, Sergio; Gómez Vallejo, Vanessa; Ríos, Xabier; San Sebastián, Eneko; Sidorenko, Valeria; Di Silvio, Desirè; Suck, Meina; De Lorenzi, Federica; Yokota Rizzo, Larissa; von Stillfried, Saskia; Kilk, Kalle; Lammers, Twan; Moya, Sergio E.; Teesalu, Tambet (2018). Application of polymersomes engineered to target p32 protein for detection of small breast tumors in mice. Oncotarget, 9 (27), 18682−18697.10.18632/oncotarget.24588.
1.1.
2018
Simon-Gracia, Lorena; Hunt, Hedi; Teesalu, Tambet (2018). Peritoneal carcinomatosis targeting with tumor homing peptides. Macromolecules, 23, 1190.10.3390/molecules23051190.
1.1.
2017
Hideki Ikemoto, Prakash Lingasamy, Anne-Mari Anton Willmore, Hedi Hunt, Kaarel Kurm, Olav Tammik, Pablo Scodeller, Lorena Simón-Gracia, Venkata Ramana Kotamraju, Andrew M Lowy, Kazuki N Sugahara, Tambet Teesalu (2017). Hyaluronan-binding peptide for targeting peritoneal carcinomatosis. Tumor Biology, 39 (5), 1−9.10.1177/1010428317701628.
1.1.
2017
Ikemoto, Hideki; Lingasamy, Prakash; Anton Willmore, Anne-Mari; Hunt, Hedi; Kurm, Kaarel; Tammik, Olav; Scodeller, Pablo; Simón-Gracia, Lorena; Kotamraju, Venkata Ramana; Lowy, Andrew M; Sugahara, Kazuki N; Teesalu, Tambet (2017). Hyaluronan-binding peptide for targeting peritoneal carcinomatosis. Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine, 39 (5), 1−9.10.1177/1010428317701628.
1.1.
2017
Scodeller, Pablo; Simón-Gracia, Lorena; Kopanchuk, Sergei; Tobi, Allan; Kilk, Kalle; Säälik, Pille; Kurm, Kaarel; Squadrito, Mario Leonardo; Kotamraju, Venkata Ramana; Rinken, Ago; De Palma, Michele; Ruoslahti, Erkki; Teesalu, Tambet (2017). Precision Targeting of Tumor Macrophages with a CD206 Binding Peptide. Scientific Reports, 7 (1), 14655−14655.10.1038/s41598-017-14709-x.
1.1.
2017
Hunt, H.; Simón-Gracia, L.; Tobi, A.; Kotamraju, V.R.; Sharma, S.; Nigul, M.; Sugahara, K.N.; Ruoslahti, E.; Teesalu, T. (2017). Targeting of p32 in peritoneal carcinomatosis with intraperitoneal linTT1 peptide-guided pro-apoptotic nanoparticles. Journal of Controlled Release, 260 (260), 142−153.10.1016/j.jconrel.2017.06.005.
3.1.
2017
Rauwel, E.; Simón-Gracia, L.; Guha, M.; Rauwel, P.; Kuunal, S.; Wragg, D. (2017). Silver metal nanoparticles study for biomedical and green house applications. IOP Conference Series: Materials Science and Engineering, 175, 1−5.10.1088/1757-899X/175/1/012011.
1.1.
2016
Simon-Gracia, Lorena; Hunt, Hedi; Scodeller, Pablo D; Gaitzsch, Jens; Braun, Gary B; Willmore, Anne-Mari A; Ruoslahti, Erkki; Battaglia, Giuseppe; Teesalu, Tambet (2016). Paclitaxel-Loaded Polymersomes for Enhanced Intraperitoneal Chemotherapy. Molecular cancer therapeutics, 15, 670−679.10.1158/1535-7163.MCT-15-0713-T.
1.1.
2016
Willmore, Anne-Mari A.; Simon-Gracia, Lorena; Toome, Kadri; Paiste, Päärn; Kotamraju, Venkata Ramana; Mölder, Tarmo; Sugahara, Kazuki N.; Ruoslahti, Erkki; Braun, Gary B.; Teesalu, Tambet (2016). Targeted silver nanoparticles for ratiometric cell phenotyping. Nanoscale, 8 (17), 9096−9101.10.1039/c5nr07928d.
1.1.
2016
Simón-Gracia, Lorena; Hunt, Hedi; Scodeller, Pablo; Gaitzsch, Jens; Kotamraju, Ventaka R; Sugahara, Kazuki N; Tammik, Olav; Ruoslahti, Erkki; Battaglia, Giuseppe; Teesalu, Tambet (2016). iRGD peptide conjugation potentiates intraperitoneal tumor delivery of paclitaxel with polymersomes. Biomaterials, 104, 247−257.10.1016/j.biomaterials.2016.07.023.
1.1.
2015
Fransen, Peter; Pulido, Daniel; Simón-Gracia, Lorena; Candiota, Ana Paula; Arús, Carles; Albericio, Fernando; Royo, Miriam (2015). r1 and r2 relaxivities of dendrons based on a OEG-DTPA architecture: effect of Gd3+ placement and dendron functionalization. Journal of Nanotechnology, 2015, 848020.10.1155/2015/848020.
1.1.
2014
Simon Gracia, Lorena (2014). Liposomes containing NY‑ESO‑1/tetanus toxoid and adjuvant peptides targeted to human dendritic cells via the Fc receptor for cancer vaccines. Nanomedicine, 9 (4), 435−449.10.2217/nnm.13.66.
1.1.
2013
Simon Gracia, Lorena (2013). Enhanced drug delivery to melanoma cells using PMPC-PDPA polymersomes. Cancer Letters, 334 (2), 328−337.10.1016/j.canlet.2013.02.007.
1.1.
2013
Simón-Gracia, L.; Pulido, D.; Sevrin, C.; Grandfils, C.; Albericio, F.; Royo, M. (2013). Biocompatible, multifunctional, and well-defined OEG-based dendritic platforms for biomedical applications. Organic and Biomolecular Chemistry, 11 (24), 4109−4121.10.1039/c3ob40492g.
1.1.
2011
Simon Gracia, Lorena (2011). Targeting nanosystems to human DCs via Fc receptor as an effective strategy to deliver antigen for immunotherapy. Molecular Pharmaceutics, 8 (1), 104−116.10.1021/mp100178k.
4.03.2020

Otsi projekti

  • {{item.Name}}
Asutus on projekti finantseerija   Asutus on projekti teostaja  
  • {{searchListItem.Name}}
Kõik   Tavaprojektid   Ülemprojektid   Alamprojektid  
Uus Frascati (2015)
Uus ja vana Frascati (otsing uue järgi väljastab ka seotud vanad)
Kõik
Käimasolevad
Lõppenud
Algus
Hajus
Täpne
Lihtotsing Tühjenda
  • Leitud 8 kirjet
ProgrammLiikNumberNimiProjekti algusProjekti lõppVastutav täitjaAsutusFinantseerijapoolne rahastamine
MUUMARMP11194RAjukasvajaid penetreerivate peptiidide väljatöötamine01.01.201231.12.2016Tambet TeesaluTartu Ülikool, Arstiteaduskond, Üld- ja molekulaarpatoloogia instituut; Tartu Ülikool, Meditsiiniteaduste valdkond, bio- ja siirdemeditsiini instituut; Tartu Ülikool, Arstiteaduskond, Bio- ja siirdemeditsiini instituut1 499 931,00 EUR
MUUMARMP11197Glioomipenetreerivad peptiidid01.01.201231.12.2016Tambet TeesaluTartu Ülikool, Arstiteaduskond, Biomeditsiini instituut; Tartu Ülikool, Meditsiiniteaduste valdkond, bio- ja siirdemeditsiini instituut; Tartu Ülikool, Arstiteaduskond, Bio- ja siirdemeditsiini instituut250 000,00 EUR
PRGPRG230Hematoentsefaalbarjääri penetreerivad kullerpeptiidid 01.01.201831.12.2022Tambet TeesaluTartu Ülikool, Meditsiiniteaduste valdkond, bio- ja siirdemeditsiini instituut649 875,00 EUR
1.2.3.4.MMVBS18435R (823879)Hemoglobiinil põhinevad nanoosakesed vähkkasvajate ravi võimendamiseks 01.03.201928.02.2023Tambet TeesaluTartu Ülikool, Meditsiiniteaduste valdkond, bio- ja siirdemeditsiini instituut156 400,00 EUR
MUUMARBS13184RHübriidsete fluorestseeruvate proovide väljatöötamine vähidiagnostikaks01.11.201331.10.2016Tambet TeesaluTartu Ülikool, Arstiteaduskond, Bio- ja siirdemeditsiini instituut; Tartu Ülikool, Meditsiiniteaduste valdkond, bio- ja siirdemeditsiini instituut; Tartu Ülikool, Arstiteaduskond, Biomeditsiini instituut54 600,00 EUR
MUUMARMP12102Kudepenetreerivate kullerpeptiidide väljatöötamine01.06.201231.05.2017Tambet TeesaluTartu Ülikool, Meditsiiniteaduste valdkond, bio- ja siirdemeditsiini instituut; Tartu Ülikool, Arstiteaduskond, Biomeditsiini instituut; Tartu Ülikool, Arstiteaduskond, Bio- ja siirdemeditsiini instituut1 303 951,00 EUR
MOBJDMOBJD11Polümeersed nano-osakesed glioblastoomi ekperimentaalteraapiaks16.09.201715.09.2019Lorena Simon GraciaTartu Ülikool, Meditsiiniteaduste valdkond, bio- ja siirdemeditsiini instituut65 835,00 EUR
EAGEAG79Rakuvälisele maatriksile suunatud soliidtuumorite täppisteraapia arendustöö01.01.202031.12.2020Tambet TeesaluTartu Ülikool, Meditsiiniteaduste valdkond, bio- ja siirdemeditsiini instituut100 000,00 EUR