Merle Mandel

https://www.etis.ee/CV/Merle_Mandel/est
merle.mandel@ut.ee

Teenistuskäik

Töökohad ja ametid
01.06.2016–31.05.2021   
Tartu Ülikool, Meditsiiniteaduste valdkond, bio- ja siirdemeditsiini instituut, farmakoloogia nooremteadur (1,00)
01.01.2016–31.05.2016   
Tartu Ülikool, Meditsiiniteaduste valdkond, bio- ja siirdemeditsiini instituut, spetsialist (1,00)
01.09.2015–31.12.2015   
Tartu Ülikool, Arstiteaduskond, Biomeditsiini instituut, spetsialist (1,00)
01.01.2014–31.08.2015   
Tartu Ülikool, Arstiteaduskond, Biomeditsiini instituut, spetsialist (0,50)
01.09.2012–31.12.2013   
Tallinna Tehnikaülikool, TTÜ Küberneetika Instituut, tehnik (0,50)
03.01.2011–31.08.2012   
Tallinna Tehnikaülikool, TTÜ Küberneetika Instituut, tehnik (1,00)
 
 
Haridustee
2012–...   
Tartu Ülikool, Meditsiiniteaduste valdkond, neuroteadused, doktoriõpe
 
 
Teadusorganisatsiooniline ja -administratiivne tegevus
2012−...   
Eesti Farmakoloogia Selts

Lõppenud projektid

Publikatsioonid

Klass
Aasta
Publikatsioon
 
1.1.
2016
Tammiku-Taul, J.; Park, R.; Jaanson, K.; Luberg, K.; Dobchev, D. A.; Kananovich, D.; Noole, A.; Mandel, M.; Kaasik, A.; Lopp, M.; Timmusk, T.; Karelson, M. (2016). Indole-like Trk receptor antagonists. European Journal of Medicinal Chemistry, 121, 541−552.10.1016/j.ejmech.2016.06.003.
1.1.
2016
Vaarmann, Annika; Mandel, Merle; Zeb, Akbar; Wareski, Przemyslaw; Liiv,Joanna; Kuum, Malle; Antsov, Eva; Liiv,Mailis; Cagalinec, Michal; Choubey, Vinay; Kaasik, Allen (2016). Mitochondrial biogenesis is required for axonal growth. Development, 143 (11), 1981−1992.10.1242/dev.128926.
5.2.
2016
Tammiku-Taul, J.; Park, R.; Jaanson, K.; Luberg, K.; Dobchev, D.A.; Kananovich, D.; Noole, A.; Mandel, M.; Kaasik, A.; Lopp, M.; Timmusk, T.; Karelson, M. (2016). Indole-like Trk receptor antagonists. 21st European Symposium on Quantitative Structure-Activity Relationship (EuroQSAR 2016), Verona, Italy, September 4-8. Self-published by conference organizers, in Book of Abstracts: p. 242.
1.1.
2015
Heinla, I.; Leidmaa, E.; Kongi, K.; Pennert, A.; Innos, J.; Nurk, K.; Tekko, T.; Singh, K.; Vanaveski, T.; Reimets, R.; Mandel, M.; Lang, A.; Lilleväli, K.; Kaasik, A.; Vasar, E.; Philips, MA. (2015). Gene expression patterns and environmental enrichment-induced effects in the hippocampi of mice suggest importance of Lsamp in plasticity. Frontiers in Neuroscience, 9 (205), 1−8.10.3389/fnins.2015.00205.
1.1.
2014
Sepp, Mervi; Sokolova, Niina; Jugai, Svetlana; Mandel, Merle; Peterson, Pearu; Vendelin, Marko (2014). Tight coupling of Na+/K+-ATPase with glycolysis demonstrated in permeabilized rat cardiomyocytes. PLoS ONE, 9 (6), e99413, 1−12.10.1371/journal.pone.009941.
5.1.
2013
Kotlyarova, Svetlana; Mandel, Merle; Sokolova, Niina; Aksentijevic, Dunja; Lygate, Craig A.; Neubauer, Stefan; Vendelin, Marko; Birkedal, Rikke (2013). Cardiomyocytes from creatine-deficient mice lacking L-arginine: glycine amidinotransferase (AGAT) show no changes in mitochondrial organization and cellular compartmentation. Biophysical Journal, 104, 303a.10.1016/j.bpj.2012.11.1686.
5.2.
2013
Kotlyarova, S.; Mandel, M.; Sokolova, N.; Aksentijevic, D.; Lygate, C.A.; Neubauer, S.; Vendelin, M.; Birkedal, R. (2013). Cardiomyocytes from creatine deficient AGAT mice show no changes in mitochondrial organization and cellular compartmentation. Proceedings of the Physiological Society : 37th Congress of IUPS (Birmingham, UK), Abstracts. Birmingham: The Physiological Society, 266−267.
18.04.2019

Merle Mandel

https://www.etis.ee/CV/Merle_Mandel/eng
merle.mandel@ut.ee

Career

Institution(s) and position(s)
01.06.2016–31.05.2021   
University of Tartu, Faculty of Medicine, Institute of Biomedicine and Translational Medicine, Junior Research Fellow of Pharmacology (1,00)
01.01.2016–31.05.2016   
University of Tartu, Faculty of Medicine, Institute of Biomedicine and Translational Medicine, Specialist (1,00)
01.09.2015–31.12.2015   
University of Tartu, Faculty of Medicine, Institute of Biomedicine, Specialist (1,00)
01.01.2014–31.08.2015   
University of Tartu, Faculty of Medicine, Institute of Biomedicine, Specialist (0,50)
01.09.2012–31.12.2013   
Tallinn University of Technology , Institute of Cybernetics at TUT, Technician (0,50)
03.01.2011–31.08.2012   
Tallinn University of Technology , Institute of Cybernetics at TUT, Technician (1,00)
 
 
Education
2012–...   
University of Tartu, Faculty of Medicine, Neurosciences, PhD student
 
 
R&D related managerial and administrative work
2012−...   
Estonian Society of Pharmacology

Completed projects

Publications

Category
Year
Publication
 
1.1.
2016
Tammiku-Taul, J.; Park, R.; Jaanson, K.; Luberg, K.; Dobchev, D. A.; Kananovich, D.; Noole, A.; Mandel, M.; Kaasik, A.; Lopp, M.; Timmusk, T.; Karelson, M. (2016). Indole-like Trk receptor antagonists. European Journal of Medicinal Chemistry, 121, 541−552.10.1016/j.ejmech.2016.06.003.
1.1.
2016
Vaarmann, Annika; Mandel, Merle; Zeb, Akbar; Wareski, Przemyslaw; Liiv,Joanna; Kuum, Malle; Antsov, Eva; Liiv,Mailis; Cagalinec, Michal; Choubey, Vinay; Kaasik, Allen (2016). Mitochondrial biogenesis is required for axonal growth. Development, 143 (11), 1981−1992.10.1242/dev.128926.
5.2.
2016
Tammiku-Taul, J.; Park, R.; Jaanson, K.; Luberg, K.; Dobchev, D.A.; Kananovich, D.; Noole, A.; Mandel, M.; Kaasik, A.; Lopp, M.; Timmusk, T.; Karelson, M. (2016). Indole-like Trk receptor antagonists. 21st European Symposium on Quantitative Structure-Activity Relationship (EuroQSAR 2016), Verona, Italy, September 4-8. Self-published by conference organizers, in Book of Abstracts: p. 242.
1.1.
2015
Heinla, I.; Leidmaa, E.; Kongi, K.; Pennert, A.; Innos, J.; Nurk, K.; Tekko, T.; Singh, K.; Vanaveski, T.; Reimets, R.; Mandel, M.; Lang, A.; Lilleväli, K.; Kaasik, A.; Vasar, E.; Philips, MA. (2015). Gene expression patterns and environmental enrichment-induced effects in the hippocampi of mice suggest importance of Lsamp in plasticity. Frontiers in Neuroscience, 9 (205), 1−8.10.3389/fnins.2015.00205.
1.1.
2014
Sepp, Mervi; Sokolova, Niina; Jugai, Svetlana; Mandel, Merle; Peterson, Pearu; Vendelin, Marko (2014). Tight coupling of Na+/K+-ATPase with glycolysis demonstrated in permeabilized rat cardiomyocytes. PLoS ONE, 9 (6), e99413, 1−12.10.1371/journal.pone.009941.
5.1.
2013
Kotlyarova, Svetlana; Mandel, Merle; Sokolova, Niina; Aksentijevic, Dunja; Lygate, Craig A.; Neubauer, Stefan; Vendelin, Marko; Birkedal, Rikke (2013). Cardiomyocytes from creatine-deficient mice lacking L-arginine: glycine amidinotransferase (AGAT) show no changes in mitochondrial organization and cellular compartmentation. Biophysical Journal, 104, 303a.10.1016/j.bpj.2012.11.1686.
5.2.
2013
Kotlyarova, S.; Mandel, M.; Sokolova, N.; Aksentijevic, D.; Lygate, C.A.; Neubauer, S.; Vendelin, M.; Birkedal, R. (2013). Cardiomyocytes from creatine deficient AGAT mice show no changes in mitochondrial organization and cellular compartmentation. Proceedings of the Physiological Society : 37th Congress of IUPS (Birmingham, UK), Abstracts. Birmingham: The Physiological Society, 266−267.
18.04.2019
Detailne otsing
  • Leitud 4 kirjet
ProgrammLiikNumberNimiProjekti algusProjekti lõppVastutav täitjaAsutusFinantseerijapoolne rahastamine
ETFETF7991MITOFAAGIA ROLL NEURODEGENERATIIVSETE HAIGUSTE KORRAL01.01.200931.12.2012Allen KaasikTartu Ülikool, Arstiteaduskond103 075,96 EUR
IUTIUT2-5Mitokondrite biogenees, dünaamika ja mitofaagia neurodegeneratiivsete haiguste korral01.01.201331.12.2018Allen KaasikTartu Ülikool, Meditsiiniteaduste valdkond, bio- ja siirdemeditsiini instituut1 068 000,00 EUR
SFSF0140077s08Mittelineaarne dünaamika ja komplekssüsteemid01.01.200831.12.2013Jüri EngelbrechtTallinna Tehnikaülikool, TTÜ Küberneetika Instituut1 825 683,65 EUR
TKTK124Mittelineaarsete protsesside analüüsi keskus01.01.201131.12.2015Jüri EngelbrechtTallinna Tehnikaülikool, TTÜ Küberneetika Instituut; Tartu Ülikool, Loodus- ja tehnoloogiateaduskond, Tartu Ülikooli Füüsika Instituut2 729 927,47 EUR