2.02.1977
mingmei.shang@ki.se

Teenistuskäik

Töökohad ja ametid
2011–...   
Tartu Ülikool, Arstiteaduskond, Patoloogilise anatoomia ja kohtuarstiteaduse instituut, Vanemteadur (0,50)
01.01.2009–...   
Clinical Gene Networks AB
 
 
Haridustee
1999–2004   
Beijing Insitute of Radiation Medicine
1995–1999   
Shandong University
 
 
Teenistuskäigu lisainfo
Main Publications:
In English
1. Hagg S, Skogsberg J, Lundstrom J, Noori P, Nilsson R, Zhong H, Maleki S, Shang M, Brinne B, Bradshaw M, et al. Muti-organ expression profiling uncovers a gene module in coronary artery disease involving transendothelial migration of leukocytes and LIM domain binding 2. PLoS Genet 2009; 5(12): e1000754.
2. Bjorklund O, Shang M, Tonazzini I, Dare E and Fredholm BB. Adenosine A1 and A3 receptors protect astrocytes from hypoxic damage. Eur J Pharmacol 2008; 596: 6-13.
3. Wang Q, Li X, Dai S, Ou L, Zhu BZ, Chen F, Shang M, Song H. Quantification of puerarin in plasma by on-line solid-phase extraction column switching liquid chromatography-tandem mass spectrometry and its applications to a pharmacokinetic study. J Chromatogr B Analyt Technol Biomed Life Sci 2008; 863(1): 55-63.
4. Du H, Xia S, Song H, Li N, Shang M, Zou J, Wang Q, Ou L, Sun X, Ji A, Tang ZM. Structure-efficacy relationships of immunostimulatory activity of CpG-containing oligodeoxynucleotides on mouse spleen cells. Acta Pharmacol Sin, 2007; 28(10): 1637-44.
5. Shang M, Song H, Liu X, Tang ZM. Detection and quantitation of PS20, a phosphorothioate oligodeoxynucleotides in monkey plasma. Acta Pharmacol Sin 2004; 25(6): 801-6.
6. Shang M, Liu X, Song H, Tang ZM. Separation of oligonucleotides by non-gel sieving capillary electropherosis. Asia Journal of drug Metabolism and Pharmacokinetics 2003; 3(2): 151-5.
7. Shang M,Liu X,Tang ZM,Song H,Chen HP.Quantitation of antisense oligonucleotides in the presence of internal standard using capillary electrophoresis.Electrophoresis (submitted)
In Chinese
1. Li P, Shang M, Wang Q, Fu J, Song HF, Liu XW, Tang ZM. Study on changes of inhibitory effect of HER-2-specific antisense phosphorothioate oligodeoxynucleotides on target gene and subcellular distribution. Bull Acad Mil Med Sci 2008; 32(5): 1-7.
2. Li P, Shang M, Song HF. Advancements in non-Viral gene delivery techniques. Chin J New Drugs 2008, 17(10): 1-5.
3. Shang M, Liu X, Tang Z, Chen HP. Recent advance in pharmacokinetics researches for antisense oligonucleotides. Foreign Medical Sciences, Section of Pharmacy 2004; 31(4): 1-5.
4. Shang M, Liu X, Song H, Tang ZM and Chen HP. Initial researches for the method of Separation of oligonucleotides with difference of a single base in sequence from each other by non-gel sieving capillary electrophoresis. Bull Acad Mil Med Sci 2005; 268-71.
5. Shang M, Liu XW, Song H, Chen HP, Tang ZM. Initial researches of fluorescent probe method for quantitation of phosphorothioate oligonucleotides, PS20 in plasma. Chin J Pharmacol Toxicol 2005; 19(6): 458-61.
6. Sheng L, Ye P, Liu Y, Zhao Y, Cui C, Shang M, Wu F. Atorvastatin Inhibits Hypertrophy and Upragulate the Expression of Peroxisome Proliferator-Activated Receptors beta/delta in Neonatal Rat Cardiomyocytes in Vitro. Chin J Arteriosclerosis 2005; 13(6): 681-4.
7. Li X, Wang Q, Sun X, Ou L, Shang M, Song H. An on-line solid phase extraction column switching liquid chromatography tandem mass spectrometry system to quantification of puerarin in beagle plasma. Bull Acad Mil Med Sci 2007; 31(3): 246-9.
8. Chen F, Song H, Shang M,Ou L, Zhu B, Sun X, Liu X. Prepartion and purification of 125I-labeled PEGylated thymosin α1. Chin J Radiological Meddicine and Protection 2005; 25(6): 505-8.
9. Liu H, Shang M, Song H. The Effects of Pegylation on the Pharmacokinetics of Polypeptide. Letters in Biotechnology 2005; 16(5): 577-9.
;

Kvalifikatsioon

 
 
Teadustöö põhisuunad
VALDKOND: 3. Terviseuuringud; 3.11. Terviseuuringutega seotud uuringud, näiteks biokeemia, geneetika, mikrobioloogia, biotehnoloogia, molekulaarbioloogia, rakubioloogia, biofüüsika ja bioinformaatika
VALDKOND: 3. Terviseuuringud; 3.3. Farmaatsia
 
 
Lisainfo
Academic conference:
2006.07 15th International Pharmacology conference Poster
2005.07 3rd National Conference of the Proteomics Poster
2004.10 5th China-France Pharmacological Joint Symposium Oral speaker
2003.10 7th National Conference of the Drug Metabolism and Pharmacokinetics Oral speaker
Obtained Grants:
2010-2011 Loo Hans Ostermans Foundation Principal Investigator
2009-2010 Karolinska Foundation Principal Investigator
2005-2008 National Nature Science Foundation of China Principal Investigator
2004-2006 The Young Plants Foundation of the BIRM Principal Investigator
8.05.2018
2.02.1977
mingmei.shang@ki.se

Career

Institution(s) and position(s)
2011–...   
University of Tartu, Faculty of Medicine, Department of Pathological Anatomy and Forensic Medicine, Senior Researcher (0,50)
01.01.2009–...   
Clinical Gene Networks AB
 
 
Education
1999–2004   
1995–1999   
 
 
Additional career information
Main Publications:
In English
1. Hagg S, Skogsberg J, Lundstrom J, Noori P, Nilsson R, Zhong H, Maleki S, Shang M, Brinne B, Bradshaw M, et al. Muti-organ expression profiling uncovers a gene module in coronary artery disease involving transendothelial migration of leukocytes and LIM domain binding 2. PLoS Genet 2009; 5(12): e1000754.
2. Bjorklund O, Shang M, Tonazzini I, Dare E and Fredholm BB. Adenosine A1 and A3 receptors protect astrocytes from hypoxic damage. Eur J Pharmacol 2008; 596: 6-13.
3. Wang Q, Li X, Dai S, Ou L, Zhu BZ, Chen F, Shang M, Song H. Quantification of puerarin in plasma by on-line solid-phase extraction column switching liquid chromatography-tandem mass spectrometry and its applications to a pharmacokinetic study. J Chromatogr B Analyt Technol Biomed Life Sci 2008; 863(1): 55-63.
4. Du H, Xia S, Song H, Li N, Shang M, Zou J, Wang Q, Ou L, Sun X, Ji A, Tang ZM. Structure-efficacy relationships of immunostimulatory activity of CpG-containing oligodeoxynucleotides on mouse spleen cells. Acta Pharmacol Sin, 2007; 28(10): 1637-44.
5. Shang M, Song H, Liu X, Tang ZM. Detection and quantitation of PS20, a phosphorothioate oligodeoxynucleotides in monkey plasma. Acta Pharmacol Sin 2004; 25(6): 801-6.
6. Shang M, Liu X, Song H, Tang ZM. Separation of oligonucleotides by non-gel sieving capillary electropherosis. Asia Journal of drug Metabolism and Pharmacokinetics 2003; 3(2): 151-5.
7. Shang M,Liu X,Tang ZM,Song H,Chen HP.Quantitation of antisense oligonucleotides in the presence of internal standard using capillary electrophoresis.Electrophoresis (submitted)
In Chinese
1. Li P, Shang M, Wang Q, Fu J, Song HF, Liu XW, Tang ZM. Study on changes of inhibitory effect of HER-2-specific antisense phosphorothioate oligodeoxynucleotides on target gene and subcellular distribution. Bull Acad Mil Med Sci 2008; 32(5): 1-7.
2. Li P, Shang M, Song HF. Advancements in non-Viral gene delivery techniques. Chin J New Drugs 2008, 17(10): 1-5.
3. Shang M, Liu X, Tang Z, Chen HP. Recent advance in pharmacokinetics researches for antisense oligonucleotides. Foreign Medical Sciences, Section of Pharmacy 2004; 31(4): 1-5.
4. Shang M, Liu X, Song H, Tang ZM and Chen HP. Initial researches for the method of Separation of oligonucleotides with difference of a single base in sequence from each other by non-gel sieving capillary electrophoresis. Bull Acad Mil Med Sci 2005; 268-71.
5. Shang M, Liu XW, Song H, Chen HP, Tang ZM. Initial researches of fluorescent probe method for quantitation of phosphorothioate oligonucleotides, PS20 in plasma. Chin J Pharmacol Toxicol 2005; 19(6): 458-61.
6. Sheng L, Ye P, Liu Y, Zhao Y, Cui C, Shang M, Wu F. Atorvastatin Inhibits Hypertrophy and Upragulate the Expression of Peroxisome Proliferator-Activated Receptors beta/delta in Neonatal Rat Cardiomyocytes in Vitro. Chin J Arteriosclerosis 2005; 13(6): 681-4.
7. Li X, Wang Q, Sun X, Ou L, Shang M, Song H. An on-line solid phase extraction column switching liquid chromatography tandem mass spectrometry system to quantification of puerarin in beagle plasma. Bull Acad Mil Med Sci 2007; 31(3): 246-9.
8. Chen F, Song H, Shang M,Ou L, Zhu B, Sun X, Liu X. Prepartion and purification of 125I-labeled PEGylated thymosin α1. Chin J Radiological Meddicine and Protection 2005; 25(6): 505-8.
9. Liu H, Shang M, Song H. The Effects of Pegylation on the Pharmacokinetics of Polypeptide. Letters in Biotechnology 2005; 16(5): 577-9.
;

Qualifications

 
 
Field of research
FIELD OF RESEARCH: 3. Health; 3.11. Biochemistry, Genetics, Microbiology, Biotechnology, Molecular Biology, Cell Biology, Biophysics and Bioinformatics relating to Health Studies
FIELD OF RESEARCH: 3. Health; 3.3. Pharmacy
 
 
Additional information
Academic conference:
2006.07 15th International Pharmacology conference Poster
2005.07 3rd National Conference of the Proteomics Poster
2004.10 5th China-France Pharmacological Joint Symposium Oral speaker
2003.10 7th National Conference of the Drug Metabolism and Pharmacokinetics Oral speaker
Obtained Grants:
2010-2011 Loo Hans Ostermans Foundation Principal Investigator
2009-2010 Karolinska Foundation Principal Investigator
2005-2008 National Nature Science Foundation of China Principal Investigator
2004-2006 The Young Plants Foundation of the BIRM Principal Investigator
8.05.2018
  • Leitud 3 kirjet
PublikatsioonAutoridAastaVäljaande pealkiriKlassifikaatorFailAsutused
Multi-organ expression profiling uncovers a gene module in coronary artery disease involving transendothelial migration of leukocytes and LIM domain binding 2: the Stockholm Atherosclerosis Gene Expression (STAGE) studyHägg, S.; Skogsberg, J.; Lundström, J.; Noori, P.; Nilsson, R.; Zhong, H.; Maleki, S.; Shang, MM.; Brinne, B.; Bradshaw, M.; Bajic, VB.; Samnegård, A.; Silveira, A.; Kaplan, LM.; Gigante, B.; Leander, K.; deFaire, U.; Rosfors, S.; Lockowandt, U.; Liska, J. ... Björkegren, J.2009PLOS Genetics1.1.Tartu Ülikool;
Tartu Ülikool, Arstiteaduskond, Patoloogilise anatoomia ja kohtuarstiteaduse instituut;
Karolinska Instituet
Adenosine A(1) and A(3) receptors protect astrocytes from hypoxic damageBjorklund, O; Shang, M; Tonazzini, I; Dare, E; Fredholm, BB.2008European Journal of Pharmacology1.1.Tartu Ülikool, Arstiteaduskond, Patoloogilise anatoomia ja kohtuarstiteaduse instituut
Detection and quantitation of PS20, a phosphorothioate oligodeoxynucleotides in monkey plasma Shang, M.; Song, H.; Liu, X.; Tang, ZM.2004Acta Pharmacologica Sinica1.1.Tartu Ülikool, Arstiteaduskond, Patoloogilise anatoomia ja kohtuarstiteaduse instituut