See veebileht kasutab küpsiseid kasutaja sessiooni andmete hoidmiseks. Veebilehe kasutamisega nõustute ETISe kasutustingimustega. Loe rohkem
Olen nõus
20.02.1987
+4917683014140
+4917683014140
olga.jasnovidova@gmail.com

Teenistuskäik

Töökohad ja ametid
01.01.2021–...   
Max Planck Institute for Molecular Genetics (Dr. Tugce Aktas Research Group), Järeldoktor (1,00)
01.09.2018–31.12.2020   
Max Planck Institute for Molecular Genetics (Dr. Andreas Mayer Research Group), Järeldoktor (1,00)
01.01.2010–01.08.2018   
Masaryk University, Central European Institute of Technology, Brno, Czech Republic, spetsialist, spetsialist (1,00)
2007–2010   
Quattromed HTI Laborid OÜ, laborant (0,50)
29.05.2006–03.09.2006   
Tartu Ülikool, Bioloogia-geograafiateaduskond, Zooloogia ja hüdrobioloogia instituut, laborant (0,20)
 
 
Haridustee
2010–01.03.2018   
Masaryk University, CEITEC, Tsehhi, doktorantuur
2008–2010   
TÜ Ülikool,molekullar- ja rakubioloogia, magistriõpe
2005–2008   
TÜ Ülikool, bioloogia bakalauruseõpe
2001–2005   
TÜ Teaduskool, keemia
1993–2005   
Tallinna 53. Keskkool

Kvalifikatsioon

6.06.2021
20.02.1987
+4917683014140
+4917683014140
olga.jasnovidova@gmail.com

Career

Institutions and positions
01.01.2021–...   
Max Planck Institute for Molecular Genetics (Dr. Tugce Aktas Research Group), Post-Doc (1,00)
01.09.2018–31.12.2020   
Max Planck Institute for Molecular Genetics (Dr. Andreas Mayer Research Group), Post-Doc (1,00)
01.01.2010–01.08.2018   
Masaryk University, Central European Institute of Technology, Brno, Czech Republic, spetsialist, Masaryk University, Central European Institute of Technology, Brno, Czech Republic, specialist (1,00)
2007–2010   
Quattromed HTI Laborid OÜ, Laboratory technician, molecular diagnostics, quality control (0,50)
29.05.2006–03.09.2006   
University of Tartu, Faculty of Biology and Geography, Institute of Zoology and Hydrobiology, Laboratory Assistant (0,20)
 
 
Education
2010–01.03.2018   
Masaryk University, CEITEC, Czech Republic, PhD in Biomolecular chemistry
2008–2010   
University of Tartu, M.Sc. in molecular and cell biology
2005–2008   
University of Tartu, B.Sc. in biology
2001–2005   
The Science School of University of Tartu, Chemistry
1993–2005   
Tallinn 53rd Secondary School

Qualifications

 
 
Fields of research
ETIS CLASSIFICATION: 4. Natural Sciences and Engineering; 4.16. Biotechnology relating to Natural Sciences and Engineering; CERCS CLASSIFICATION: T360 Biochemical technology ; SPECIFICATION: Structure biology, NMR, Structural biology
 
 
Additional information
Cultivation of E.coli, budding & fission yeast, K562, HEK293, HCT116, HeLa, and iPS cells. Establishing & maintenance of human neuronal differentiation system. Work with mice (FELASA B).
Design & performance of cloning; DNA & RNA isolation; design of synthetic genes.
Method development. Optimization & preparation of sequencing libraries for the native elongating transcript sequencing (NET-seq). Establishment, optimization, data collection & analysis of RNA long-read Oxford Nanopore sequencing for nascent and mRNA. Time-course experiments.
Metabolic labelling, isolation, purification, fragmentation & enzymatic treatments of nascent RNA for cloning, short- & long-read sequencing library preparation.
Optimization of protein expression in bacteria; design of large-scale protein purifications using ion-exchange, affinity and size-exclusion chromatography. Operation and maintenance of AKTA FPLC machines. Isotopic labelling of proteins for NMR; site-specific attachment of paramagnetic compounds; incorporation of unnatural amino acids. 10 years of experience.
Study of protein-protein interactions using nuclear magnetic resonance (NMR) spectroscopy, small-angle X-ray scattering (SAXS), immuno-blotting, pull-down assay, isothermal titration calorimetry (ITC) & fluorescence anisotropy (FA).
Protein NMR structures: resonance assignment, structure calculations for proteins and protein-peptide complexes. Modeling of multisubunit complexes combining NMR and SAXS data. 3 solved protein-peptide complex structures (PDB ID: 5LVF, 5M9D, 6GC3).
Protein crystallisation. 1 solved crystal structure (PDB ID: 5M48).
Viral & bacterial DNA extraction from patient material, diagnostic PCR, validation of results & quality control in commercial medical laboratory.
6.06.2021