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Pauline C. Ng

https://www.etis.ee/CV/Pauline C._Ng/est
10.12.1976
7375029
pauline.c.ng@gmail.com

Teenistuskäik

Töökohad ja ametid
2011–...   
Tartu Ülikool, Tartu Ülikooli Eesti Geenivaramu, Erakorraline vanemteadur (0,50)
01.01.2010–...   
GENOME INSTITUTE OF SINGAPORE, Computational Biology Group Leader
01.01.2009–...   
J. CRAIG VENTER INSTITUTE, Genomic Medicine Dept., Assistant Professor
01.01.2006–31.12.2008   
J. CRAIG VENTER INSTITUTE, Genomic Medicine Dept., Senior Scientist
01.01.2005–31.12.2006   
ILLUMINA, INC., San Diego, CA, Bioinformatics Senior Scientist
01.01.2003–31.12.2005   
ILLUMINA, INC., San Diego, CA, Bioinformatics Scientist II
01.01.2002–31.12.2003   
ILLUMINA, INC., San Diego, CA, Bioinformatics Scientist I
01.01.1998–31.12.2002   
FRED HUTCHINSON CANCER RESEARCH CENTER, Seattle, WA, Bioinformatics Graduate Student
 
 
Haridustee
1997–2002   
UNIVERSITY OF WASHINGTON, Seattle, WA; G.P.A.3.9
1994–1997   
CALTECH, Pasadena, CA; G.P.A. 3.9
 
 
Teadusorganisatsiooniline ja -administratiivne tegevus
2013−2017   
Supervised PhD of Liis Leitsalu

Kvalifikatsioon

Teaduskraadid
Pauline C. Ng, doktorikraad, 2002, (juh) Steven Henikoff, PSSMs: Not just roadkill on the information superhighway, University of Washington.
 
 
Teadustöö põhisuunad
VALDKOND: 4. Loodusteadused ja tehnika; 4.6. Arvutiteadused; CERCS ERIALA: T120 Süsteemitehnoloogia, arvutitehnoloogia; PÕHISUUND: Develop personalized medicine pipelines for common disease (such as Parkinson’s) and cancer on cloud. Innovated research on individual human genomes.

Jooksvad projektid

Juhendatud väitekirjad

Publikatsioonid

Klass
Aasta
Publikatsioon
 
1.1.
2009
Harismendy, O; Ng, PC; Strausberg, RL; Wang, X; Stockwell, TB; Beeson, KY; Schork, NJ; Murray, SS; Topol, EJ; Levy, S; Frazer, KA. (2009). Evaluation of next generation sequencing platforms for population targeted sequencing studies. Genome Biology, 10 (3), R32.10.1186/gb-2009-10-3-r32.
1.1.
2009
Axelrod, N.; Lin, Y.; Ng, PC.; Stockwell, TB.; Crabtree, J.; Huang, J.; Kirkness, E.; Strausberg, RL.; Frazier, ME.; Venter, JC.; Kravitz, S.; Levy, S. (2009). The HuRef Browser: a web resource for individual human genomics. Nucleic Acids Research, 37, 1−7.
1.1.
2008
Ng, PC; Levy, S; Huang, J; Stockwell, TB; Walenz, BP; Li, K; Axelrod, N; Busam, DA; Strausberg, RL; Venter, JC. (2008). Genetic Variation in an Individual Human Exome. Plos Genetics, 4 (8), e1000160.
1.1.
2007
Eberle, MA.; Ng, PC.; Kuhn, K.; Zhou, L.; Peiffer, DA.; Galver, L.; Viaud-Martinez, KA.; Taylor Lawley, C.; Gunderson, KL.; Shen, R.; Murray, SS. (2007). Power to Detect Risk Alleles Using Genome-Wide Tag SNP Panels. Plos Genetics, 3 (10), 1827−1837.10.1371/journal.pgen.0030170.
1.1.
2007
Levy, S; Sutton, G; Ng, PC; Feuk, L; Halpern, AL; Walenz, BP; Axelrod, N; Huang, J; Kirkness, EF; Denisov, G; Lin, Y; MacDonald, JR; Pang, AWC; Shago, M; Stockwell, TB; Tsiamouri, A; Bafna, V; Bansal, V; Kravitz, SA; Busam, DA ... Venter, JC. (2007). The Diploid Genome Sequence of an Individual Human. Plos Biology, 5, x−x.e254.
1.1.
2006
Ng, P. C.; Henikoff, S. (2006). Predicting the effects of amino acid substitutions on protein function. Annual Review of Genomics and Human Genetics, 7, 61−80.
1.1.
2006
K.L. Gunderson, K.M. Kuhn, F.J. Steemers, P. Ng, S.S. Murray, R.Shen (2006). Whole-genome genotyping of haplotype tag single nucleotide polymorphisms. The pharmacogenomics journal, 7 (4), 641−648.
1.1.
2003
Ng, P.C.; Henikoff, S. (2003). SIFT: Predicting amino acid changes that affect protein function. Nucleic Acids Research, 31 (13), 3812−3814.
1.1.
2002
Ng, P.C.; Henikoff, S. (2002). Accounting for human polymorphisms predicted to affect protein function. Genome Research, 12 (3), 436−446.
1.1.
2001
Ng, P.C.; Henikoff, S. (2001). Predicting deleterious amino acid substitutions. Genome Research, 11 (5), 863−874.
1.1.
2000
Ng, P.C.; Henikoff, J.G.; Henikoff, S. (2000). PHAT: a transmembrane-specific substitution matrix. Bioinformatics, 16 (9), 760−766.
5.04.2018

Pauline C. Ng

https://www.etis.ee/CV/Pauline C._Ng/eng
10.12.1976
7375029
pauline.c.ng@gmail.com

Career

Institution and occupation
2011–...   
University of Tartu, Estonian Genome Center, Extraordinary Senior Researcher (0,50)
01.01.2010–...   
GENOME INSTITUTE OF SINGAPORE, Computational Biology Group Leader
01.01.2009–...   
J. CRAIG VENTER INSTITUTE, Genomic Medicine Dept., Assistant Professor
01.01.2006–31.12.2008   
J. CRAIG VENTER INSTITUTE, Genomic Medicine Dept., Senior Scientist
01.01.2005–31.12.2006   
ILLUMINA, INC., San Diego, CA, Bioinformatics Senior Scientist
01.01.2003–31.12.2005   
ILLUMINA, INC., San Diego, CA, Bioinformatics Scientist II
01.01.2002–31.12.2003   
ILLUMINA, INC., San Diego, CA, Bioinformatics Scientist I
01.01.1998–31.12.2002   
FRED HUTCHINSON CANCER RESEARCH CENTER, Seattle, WA, Bioinformatics Graduate Student
 
 
Education
1997–2002   
UNIVERSITY OF WASHINGTON, Seattle, WA; G.P.A.3.9
1994–1997   
CALTECH, Pasadena, CA; G.P.A. 3.9
 
 
R&D related managerial and administrative work
2013−2017   

Qualifications

Academic degrees
Pauline C. Ng, Doctor's Degree, 2002, (sup) Steven Henikoff, PSSMs: Not just roadkill on the information superhighway, University of Washington.
 
 
Field of research
FIELD OF RESEARCH: 4. Natural Sciences and Engineering; 4.6. Computer Sciences; CERCS SPECIALTY: T120 Systems engineering, computer technology ; SPECIALITY: Develop personalized medicine pipelines for common disease (such as Parkinson’s) and cancer on cloud. Innovated research on individual human genomes.
 
 

Projects in progress

Supervised dissertations

Publications

Category
Year
Publication
 
1.1.
2009
Harismendy, O; Ng, PC; Strausberg, RL; Wang, X; Stockwell, TB; Beeson, KY; Schork, NJ; Murray, SS; Topol, EJ; Levy, S; Frazer, KA. (2009). Evaluation of next generation sequencing platforms for population targeted sequencing studies. Genome Biology, 10 (3), R32.10.1186/gb-2009-10-3-r32.
1.1.
2009
Axelrod, N.; Lin, Y.; Ng, PC.; Stockwell, TB.; Crabtree, J.; Huang, J.; Kirkness, E.; Strausberg, RL.; Frazier, ME.; Venter, JC.; Kravitz, S.; Levy, S. (2009). The HuRef Browser: a web resource for individual human genomics. Nucleic Acids Research, 37, 1−7.
1.1.
2008
Ng, PC; Levy, S; Huang, J; Stockwell, TB; Walenz, BP; Li, K; Axelrod, N; Busam, DA; Strausberg, RL; Venter, JC. (2008). Genetic Variation in an Individual Human Exome. Plos Genetics, 4 (8), e1000160.
1.1.
2007
Eberle, MA.; Ng, PC.; Kuhn, K.; Zhou, L.; Peiffer, DA.; Galver, L.; Viaud-Martinez, KA.; Taylor Lawley, C.; Gunderson, KL.; Shen, R.; Murray, SS. (2007). Power to Detect Risk Alleles Using Genome-Wide Tag SNP Panels. Plos Genetics, 3 (10), 1827−1837.10.1371/journal.pgen.0030170.
1.1.
2007
Levy, S; Sutton, G; Ng, PC; Feuk, L; Halpern, AL; Walenz, BP; Axelrod, N; Huang, J; Kirkness, EF; Denisov, G; Lin, Y; MacDonald, JR; Pang, AWC; Shago, M; Stockwell, TB; Tsiamouri, A; Bafna, V; Bansal, V; Kravitz, SA; Busam, DA ... Venter, JC. (2007). The Diploid Genome Sequence of an Individual Human. Plos Biology, 5, x−x.e254.
1.1.
2006
Ng, P. C.; Henikoff, S. (2006). Predicting the effects of amino acid substitutions on protein function. Annual Review of Genomics and Human Genetics, 7, 61−80.
1.1.
2006
K.L. Gunderson, K.M. Kuhn, F.J. Steemers, P. Ng, S.S. Murray, R.Shen (2006). Whole-genome genotyping of haplotype tag single nucleotide polymorphisms. The pharmacogenomics journal, 7 (4), 641−648.
1.1.
2003
Ng, P.C.; Henikoff, S. (2003). SIFT: Predicting amino acid changes that affect protein function. Nucleic Acids Research, 31 (13), 3812−3814.
1.1.
2002
Ng, P.C.; Henikoff, S. (2002). Accounting for human polymorphisms predicted to affect protein function. Genome Research, 12 (3), 436−446.
1.1.
2001
Ng, P.C.; Henikoff, S. (2001). Predicting deleterious amino acid substitutions. Genome Research, 11 (5), 863−874.
1.1.
2000
Ng, P.C.; Henikoff, J.G.; Henikoff, S. (2000). PHAT: a transmembrane-specific substitution matrix. Bioinformatics, 16 (9), 760−766.
5.04.2018
Detailne otsing
  • Leitud 1 kirjet
ProgrammLiikNumberNimiProjekti algusProjekti lõppVastutav täitjaAsutusFinantseerijapoolne rahastamine
IUTIUT20-60Oomiksi põhised meetodid terviseuuringutes: integreeritud lähenemine haiguste tekkeprotsesside mõistmiseks ja prognoosimiseks01.01.201431.12.2019Andres MetspaluTartu Ülikool, Tartu Ülikooli Eesti Geenivaramu; Tartu Ülikool, Tartu Ülikooli genoomika instituut1 327 800,00 EUR