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Olen nõus

Reet Kurg

https://www.etis.ee/CV/Reet_Kurg/est
15.05.1965
737 5040
5341 9189 (5040)
reet.kurg@ut.ee
J-2829-2015

Teenistuskäik

Töökohad ja ametid
01.02.2021–...   
Tartu Ülikool, Loodus- ja täppisteaduste valdkond, tehnoloogiainstituut, molekulaarse biomeditsiini professor (1,00)
01.01.2003–...   
Tartu Ülikool, Loodus- ja täppisteaduste valdkond, tehnoloogiainstituut, Vanemteadur (1,00)
1988-2001 - Eesti Biokeskus, teadur
1998 - stazeerimine USA-s, Baylor College of Medicine, Texas Medical Center, Houston, Texas
2001-2002 - TÜ Tehnoloogiakeskus, erak. vanemtadur
01.01.2021–31.01.2021   
Tartu Ülikool, Loodus- ja täppisteaduste valdkond, tehnoloogiainstituut, geenitehnoloogia kaasprofessor (1,00)
01.09.2017–31.12.2020   
Tartu Ülikool, Loodus- ja täppisteaduste valdkond, tehnoloogiainstituut, geenitehnoloogia vanemteadur (1,00)
01.01.2016–31.08.2017   
Tartu Ülikool, Loodus- ja täppisteaduste valdkond, tehnoloogiainstituut, geenitehnoloogia vanemteadur (1,00)
01.05.2013–31.12.2015   
Tartu Ülikool, Loodus- ja tehnoloogiateaduskond, Tartu Ülikooli Tehnoloogiainstituut, geenitehnoloogia vanemteadur (1,00)
01.09.2012–30.04.2013   
Tartu Ülikool, Loodus- ja tehnoloogiateaduskond, Tartu Ülikooli Tehnoloogiainstituut, geenitehnoloogia vanemteadur (1,00)
01.01.2008–31.08.2012   
Tartu Ülikool, Loodus- ja tehnoloogiateaduskond, Tartu Ülikooli Tehnoloogiainstituut, geenitehnoloogia vanemteadur (1,00)
01.09.2007–31.12.2007   
Tartu Ülikool, Loodus- ja tehnoloogiateaduskond, Tartu Ülikooli Tehnoloogiainstituut, geenitehnoloogia vanemteadur (1,00)
01.01.2003–31.08.2007   
Tartu Ülikool, Loodus- ja tehnoloogiateaduskond, Tartu Ülikooli Tehnoloogiainstituut, geenitehnoloogia vanemteadur (1,00)
 
 
Haridustee
1983 - M. Härma nim. Tartu 2. Keskkool
1988 - Tartu Ülikool, füüsika-keemia teaduskond, lõpetanud kiitusega bio-orgaanilise keemia eriala
 
 
Teadusorganisatsiooniline ja -administratiivne tegevus
2018−...   
TÜ tehnoloogiainstituudi direktor
2018−...   
TÜ Loodus- ja täppisteaduste valdkonna nõukogu liige
2016−...   
COST Action CA15214 juhtkomitee liige
2015−...   
International Society for Extracellular Vesicles (ISEV) liige
2012−...   
TÜ Tehnoloogiainstituudi nõukogu liige
2011−...   
Viroloogia tuumiklabori juhataja
2006−...   
Eesti Inimesegeneetika Ühingu liige
 
 
Loometöö
..

Kvalifikatsioon

Teaduskraadid
Reet Kurg, doktorikraad, 2000, (juh) Mart Ustav, Structure-function relationship of the bovine papillomavirus E2 protein, Tartu Ülikool, Bioloogia-geograafiateaduskond, Molekulaar- ja rakubioloogia instituut.
 
 
Teaduspreemiad ja tunnustused
2017, Reet Kurg, Fotonäituse "Pane vaim valmis. Tartu Ülikooli 100 nägu" nominent
 
 
Teadustöö põhisuunad
ETIS KLASSIFIKAATOR: 1. Bio- ja keskkonnateadused; 1.12. Bio- ja keskkonnateadustega seotud uuringud, näiteks biotehnoloogia, molekulaarbioloogia, rakubioloogia, biofüüsika, majandus- ja tehnoloogiauuringud; CERCS KLASSIFIKAATOR: T490 Biotehnoloogia ; TÄPSUSTUS: Minu uurimistöö teemaks on vähi-testise antigeenide iseloomustamine ja nende roll normaalse raku muutumisel vähirakuks. Spetsiifilseks uurimisobjektiks on MAGEA perekonna valgud, nende ekspressioon kasvajates ja kasutamine nii diagnostikas kui uute, täpsemate vähivastaste ravimite väljatöötamisel.
 
 
Lisainfo
Ph.D (molekulaarbioloogia)
Tartu ülikool, 2000

Jooksvad projektid

Lõppenud projektid

Juhendamisel väitekirjad

Juhendatud väitekirjad

Publikatsioonid

Klass
Aasta
Publikatsioon
 
2.4.
2022
Merits, Andres; Abroi, Aare; Kurg, Reet; Žusinaite, Eva; Truve, Erkki; Sarmiento, Cecilia; Sõmera, Merike; Saar, Tiiu; Viltrop, Arvo; Lutsar, Irja; Avi, Radko; Karki, Tõnis; Huik, Kristi; Kõljalg, Siiri; Brilene, Tatjana; Roots, Irja;Inno, Heleri (2022). Üldine ja Meditsiiniline viroloogia. Tartu: Tartu Ülikooli kirjastus [ilmumas].
1.1.
2021
Reinsalu, Olavi; Samel, Anneli; Niemeister, Elen; Kurg, Reet (2021). MAGEA4 Coated Extracellular Vesicles Are Stable and Can Be Assembled In Vitro. International Journal of Molecular Sciences, 22 (10), 5208. DOI: 10.3390/ijms22105208.
1.1.
2021
Erenpreisa, Jekaterina; Krigerts, Jekabs; Salmina, Kristine; Gerashchenko, Bogdan; Freivalds, Talivaldis; Kurg, Reet; Winter, Ruth; Krufczik, Mattias; Zayakin, Pawel; Hausmann, Michael; Giuliani, Alessandro (2021). Heterochromatin Networks: Topology, Dynamics, and Function (a Working Hypothesis). Cells, 10 (1582), 1−25. DOI: 10.3390/ cells10071582.
6.3.
2020
Kurg, Kristiina; Kurg, Reet (2020). Melanoomi diagnoos vaid veretilgast? Kodutohter, 24−28.
6.3.
2020
Kurg, Kristiina; Kurg, Reet (2020). Skin cancer diagnostics from just a drop of blood – could it really be true? Research in Estonia, 05.11.2020.
1.1.
2019
Kuldkepp, Anneli; Karakai, Magda; Toomsoo, Eve; Reinsalu, Olavi; Kurg, Reet (2019). Cancer-testis antigens MAGEA proteins are incorporated into extracellular vesicles released by cells. Oncotarget, 10 (38), 3694−3708.10.18632/oncotarget.26979.
1.1.
2019
Leetsi, L ; Õunap, K; Abroi, A; Kurg, R (2019). The Common Partner of Several Methyltransferases TRMT112 Regulates the Expression of N6AMT1 Isoforms in Mammalian Cells. Biomolecules, 9 (9), 422. DOI: 10.3390/biom9090422.
5.2.
2019
Salmina, Kristine; Kurg, Reet; Krigerts, Jekabs; Erenpreisa, Jekaterina (2019). The topological relationship between ribogenesis, mRNA transcription/splicing and the tension of actin cytoskeletion. Biopolymers and Cell. National Academy of Sciences of Ukraine, 231−232. DOI: 10.7124/bc.0009F7.
1.1.
2018
Õunap, Kadri; Kurg, Kristiina; Võsa, Liisi; Maiväli, Ülo; Teras, Marina; Planken, Anu; Ustav, Mart; Kurg, Reet (2018). Antibody response against cancer‑testis antigens MAGEA4 and MAGEA10 in patients with melanoma. Oncology Letters, 16 (1), 211−2018. DOI: 10.3892/ol.2018.8684.
1.1.
2016
Kurg, Reet; Reinsalu, Olavi; Jagur, Sergei; Õunap, Kadri; Võsa, Liisi; Kasvandik, Sergo; Padari, Kärt; Gildemann, Kiira; Ustav, Mart (2016). Biochemical and proteomic characterization of retrovirus Gag based microparticles carrying melanoma antigens. Scientific Reports, 6 (29245), 1−11. DOI: 10.1038/srep29425.
1.1.
2015
Õunap, K.; Leetsi, L.; Matsoo, M.; Kurg, R. (2015). The Stability of Ribosome Biogenesis Factor WBSCR22 Is Regulated by Interaction with TRMT112 via Ubiquitin-Proteasome Pathway. PLoS ONE, 10 (7), e0133841. DOI: 10.1371/journal.pone.0133841.
1.1.
2015
Kivipõld, P.; Võsa, L.; Ustav, M.; Kurg, R. (2015). DAXX modulates human papillomavirus early gene expression and genome replication in U2OS cells. Virology Journal, 12, 104.10.1186/s12985-015-0335-z.
1.1.
2015
Sankovski, Eve; Karro, Kristiina; Sepp, Mari; Kurg, Reet; Ustav, Mart; Abroi, Aare (2015). Characterization of the nuclear matrix targeting sequence (NMTS) of the BPV1 E8/E2 protein - the shortest known NMTS. Nucleus, 289−300. DOI: 10.1080/19491034.2015.1074359.
1.1.
2013
Õunap, Kadri; Käsper, Ly; Kurg, Ants; Kurg, Reet (2013). The human WBSCR22 protein is involved in the biogenesis of the 40S ribosomal subunits in mammalian cells. PLoS ONE, 8 (9), nr e75686. DOI: 10.1371/journal.pone.0075686.
1.1.
2012
Võsa, L; Sudakov, A; Remm, M; Ustav, M; Kurg, R. (2012). Identification and analysis of papillomavirus E2 protein binding sites in the human genome. Journal of Virology, 86 (1), 348−357. DOI: 10.1128/JVI.05606-11.
1.1.
2012
Järving, R.; Lõokene, A.; Kurg, R.; Siimon, L.; Järving, I.; Samel, N. (2012). Activation of 11R-lipoxygenase is fully Ca(2+)-dependent and controlled by the phospholipid composition of the target membrane. Biochemistry, 51 (15), 3310−3320. DOI: 10.1021/bi201690z.
3.2.
2011
Kurg, R. (2011). The role of E2 proteins in papillomavirus DNA replication. In: Seligmann, H. (Ed.). DNA Replication - Current Advances (613−638).. Rijeka, Croatia: INTECH.
6.3.
2011
Kurg, Reet (2011). INEPO-l kohtuvad keskkonnahuvilised noored. Eesti Loodus, 8.
1.1.
2010
Kurg, R; Uusen, P; Võsa, L; Ustav, M (2010). Human papillomavirus E2 protein with single activation domain initiates HPV18 genome replication, but is not sufficient for long-term maintenance of virus genome. Virology, 408 (2), 159−166.10.1016/j.virol.2010.09.010.
1.1.
2009
Varvas, K.; Kurg, R.; Hansen, K.; Järving, R.; Järving, I.; Valmsen, K.; Lõhelaid, H.; Samel, N. (2009). Direct evidence of the cyclooxygenase pathway of prostaglandin synthesis in arthropods: Genetic and biochemical characterization of two crustacean cyclooxygenases. Insect Biochemistry and Molecular Biology, 39 (12), 851−860.
1.1.
2009
Kurg, R.; Uusen, P.; Sepp, T.; Sepp, M.; Abroi, A.; Ustav, M. (2009). Bovine papillomavirus type 1 E2 protein heterodimer is functional in papillomavirus DNA replication in vivo. Virology, 386 (2), 353−359. DOI: 10.1016/j.virol.2009.01.025.
5.1.
2008
Hansen, K.; Kurg, R.; Varvas, K.; Valmsen, K.; Järving, I.; Järving, R.; Samel, N. (2008). Cloning, expression and characterization of cyclooxygenase gene from amphipods. FEBS Journal: Joint Conference of the 33rd FEBS Congress/11th IUBMB Conference. Athens, GREECE, JUN 28-JUL 03, 2008. , 403. (275).
1.1.
2007
Denks, K.; Späeth, E.L.; Jõers, K.; Randoja, R.; Talpsep, T.; Ustav, M.; Kurg, R. (2007). Coinfection of Chlamydia trachomatis, Ureaplasma urealyticum and human papillomavirus among patients attending STD clinics in Estonia. Scandinavian Journal of Infectious Diseases, 39 (8), 714−718.
5.2.
2007
Hansen, K.; Kurg, R.; Varvas, K.; Järving, I.; Järving, R.; Valmsen, K.; Samel, N. (2007). Tsüklooksügenaas kirpvähilistest: kloneerimine, ekspresseerimine ja iseloomustamine. XXX Eesti Keemiapäevad Teaduskonverentsi teesid: XXX Eesti Keemiapäevad Tartus 16. november 2007. Toim. Rinken, A. Tartu: Tartu Ülikooli Kirjastus, 30−31.
1.1.
2006
Kurg, R; Tekkel, Helena; Abroi, Aare; Ustav, Mart (2006). Characterizarion of the functional activities of the bovine papillomavirus type 1 E2 protein single-chain heterodimers. Journal of Virology, 80 (22), 11218−11225.
1.1.
2005
Kurg, R.; Sild, K.; Ilves, A.; Sepp, M.; Ustav, M. (2005). Association of bovine papillomavirus E2 protein with nuclear structures in vivo. Journal of Virology, 79 (16), 10528−10539.
1.1.
2004
Jarving, R.; Jarving, I.; Kurg, R.; Brash, AR.; Samel, N. (2004). On the evolutionary origin of cyclooxygenase (COX) isozymes - Characterization of marine invertebrate COX genes points to independent duplication events in vertebrate and invertebrate lineages. Journal of Biological Chemistry, 279 (14), 13624−13633.
1.1.
2001
Kivimae, S.; Allikas, A.; Kurg, R.; Ustav, M. (2001). Replication of a chimeric origin containing elements from Epstein-Barr virus ori P and bovine papillomavirus minimal origin. Virus Research, 75 (1), 1−11.
1.1.
2001
Allikas, A.; Ord, D.; Kurg, R.; Kivi, S.; Ustav, M. (2001). Roles of the hinge region and the DNA binding domain of the bovine papillomavirus type 1 E2 protein in initiation of DNA replication. Virus Research, 75 (2), 95−106.
1.1.
2001
Koljak, R.; Jarving, I.; Kurg, R.; Boeglin, WE.; Varvas, K.; Valmsen, K.; Ustav, M.; Brash, AR.; Samel, N. (2001). The basis of prostaglandin synthesis in coral - Molecular cloning and expression of a cyclooxygenase from the Arctic soft coral Gersemia fruticosa. Journal of Biological Chemistry, 276 (10), 7033−7040.
1.1.
2000
Kurg, R.; Langel, U.; Ustav, M. (2000). Inhibition of the bovine papillomavirus E2 protein activity by peptide nucleic acid. Virus Research, 66 (1), 39−50.
3.2.
2000
Kurg, R; Ustav, M. (2000). Update to: Monitoring and Purification of Proteins Using Bovine Papillomavirus E2 Epitope Tags. Lu,Q.; M.P. Weiner. Cloning and Expression Vectors for Protein Studies (Chapter 27). . Weiner: Eaton Publishing Co.
1.1.
1999
Abou-Zahr, F.; Bejjani, B.; Kruyt, FAE.; Kurg, R.; Bacino, C.; Shapira, SK.; Youssoufian, H. (1999). Normal expression of the Fanconi anemia proteins FAA and FAC and sensitivity to mitomycin C in two patients with Seckel syndrome. American Journal of Medical Genetics, 83 (5), 388−391.
1.1.
1999
Kurg, R.; Parik, J.; Juronen, E.; Sedman, T.; Abroi, A.; Liiv, I.; Langel, U.; Ustav, M. (1999). Effect of bovine papillomavirus E2 protein-specific monoclonal antibodies on papillomavirus DNA replication. Journal of Virology, 73 (6), 4670−4677.
1.1.
1996
Abroi, A.; Kurg, R.; Ustav, M. (1996). Transcriptional and replicational activation functions in the bovine papillomavirus type 1 E2 protein are encoded by different structural determinants. Journal of Virology, 70 (9), 6169−6179.

Tööstusomand

15.07.2021

Reet Kurg

https://www.etis.ee/CV/Reet_Kurg/eng
15.05.1965
737 5040
5341 9189 (5040)
reet.kurg@ut.ee
J-2829-2015

Career

Institutions and positions
01.02.2021–...   
University of Tartu, Faculty of Science and Technology, Institute of Technology, Professor of Molecular Biomedicine (1,00)
01.01.2003–...   
University of Tartu, Faculty of Science and Technology, Institute of Technology, Senior Researcher (1,00)
1988-2001 - Estonian Biocentre, research associate
1998 - working at Baylor College of Medicine, Texas Medical Center, Houston, Texas
2001-2002 - Technology Center of University of Tartu, research scientist
01.01.2021–31.01.2021   
University of Tartu, Faculty of Science and Technology, Institute of Technology, Associate Professor of Gene Technology (1,00)
01.09.2017–31.12.2020   
University of Tartu, Faculty of Science and Technology, Institute of Technology, Senior Research Fellow in Gene Technology (1,00)
01.01.2016–31.08.2017   
University of Tartu, Faculty of Science and Technology, Institute of Technology, Senior Research Fellow in Gene Technology (1,00)
01.05.2013–31.12.2015   
University of Tartu, Faculty of Science and Technology (old), Institute of Technology, University of Tartu, Senior Research Fellow in Gene Technology (1,00)
01.09.2012–30.04.2013   
University of Tartu, Faculty of Science and Technology (old), Institute of Technology, University of Tartu, Senior Research Fellow in Gene Technology (1,00)
01.01.2008–31.08.2012   
University of Tartu, Faculty of Science and Technology (old), Institute of Technology, University of Tartu, Senior Research Fellow in Gene Technology (1,00)
01.09.2007–31.12.2007   
University of Tartu, Faculty of Science and Technology (old), Institute of Technology, University of Tartu, Senior Research Fellow (1,00)
01.01.2003–31.08.2007   
University of Tartu, Faculty of Science and Technology (old), Institute of Technology, University of Tartu, Senior Research Fellow (1,00)
 
 
Education
1983 - Tartu Secondary School No. 2
1988 - University of Tartu, Faculty of Physics and Chemistry, graduated cum laude as bio-organic chemist
 
 
R&D related managerial and administrative work
2018−...   
Director; UT Institute of Technology
2018−...   
Member of Council; UT Faculty of Science and Technology
2016−...   
Management Committee Member, COST Action CA15214
2015−...   
member of the International Society for Extracellular Vesicles (ISEV)
2012−...   
Member of Council; UT Institute of Technology
2011−...   
Head of the Core Facility for virology and cell imaging
2006−...   
member of the Estonian Human Genetic Society
 
 
Creative work
.

Qualifications

Academic degrees
Reet Kurg, Doctor's Degree, 2000, (sup) Mart Ustav, Structure-function relationship of the bovine papillomavirus E2 protein, University of Tartu, Faculty of Biology and Geography, Institute of Molecular and Cell Biology.
 
 
Honours & awards
2017, Reet Kurg, Travelling exhibition “Get ready! The Face of the University or 100 Teaching Staff Members of the University” in UT’s academic buildings from 1/12/2017 – 1/12/2020; nominent
 
 
Fields of research
ETIS CLASSIFICATION: 1. Biosciences and Environment; 1.12. Biotechnology, Molecular Biology, Cell Biology, Biophysics and Economic and Technological Research relating to Bio- and Environmental Sciences; CERCS CLASSIFICATION: T490 Biotechnology ; SPECIFICATION: The current focus of my research is to investigate the role of cancer-testis antigens, especially MAGEA family proteins, in the development of malignant tumors. Our aim is to target MAGEA proteins for development of biological therapeutics against MAGEA-positive tumors. A second focus concerns methyltransferases, their characterization and role in cell proliferation.
 
 
Additional information
Ph.D (molecular biology)
University of Tartu, 2000

Projects in progress

Completed projects

Dissertations under supervision

Supervised dissertations

Publications

Category
Year
Publication
 
2.4.
2022
Merits, Andres; Abroi, Aare; Kurg, Reet; Žusinaite, Eva; Truve, Erkki; Sarmiento, Cecilia; Sõmera, Merike; Saar, Tiiu; Viltrop, Arvo; Lutsar, Irja; Avi, Radko; Karki, Tõnis; Huik, Kristi; Kõljalg, Siiri; Brilene, Tatjana; Roots, Irja;Inno, Heleri (2022). Üldine ja Meditsiiniline viroloogia. Tartu: Tartu Ülikooli kirjastus [forthcoming].
1.1.
2021
Reinsalu, Olavi; Samel, Anneli; Niemeister, Elen; Kurg, Reet (2021). MAGEA4 Coated Extracellular Vesicles Are Stable and Can Be Assembled In Vitro. International Journal of Molecular Sciences, 22 (10), 5208. DOI: 10.3390/ijms22105208.
1.1.
2021
Erenpreisa, Jekaterina; Krigerts, Jekabs; Salmina, Kristine; Gerashchenko, Bogdan; Freivalds, Talivaldis; Kurg, Reet; Winter, Ruth; Krufczik, Mattias; Zayakin, Pawel; Hausmann, Michael; Giuliani, Alessandro (2021). Heterochromatin Networks: Topology, Dynamics, and Function (a Working Hypothesis). Cells, 10 (1582), 1−25. DOI: 10.3390/ cells10071582.
6.3.
2020
Kurg, Kristiina; Kurg, Reet (2020). Melanoomi diagnoos vaid veretilgast? Kodutohter, 24−28.
6.3.
2020
Kurg, Kristiina; Kurg, Reet (2020). Skin cancer diagnostics from just a drop of blood – could it really be true? Research in Estonia, 05.11.2020.
1.1.
2019
Kuldkepp, Anneli; Karakai, Magda; Toomsoo, Eve; Reinsalu, Olavi; Kurg, Reet (2019). Cancer-testis antigens MAGEA proteins are incorporated into extracellular vesicles released by cells. Oncotarget, 10 (38), 3694−3708.10.18632/oncotarget.26979.
1.1.
2019
Leetsi, L ; Õunap, K; Abroi, A; Kurg, R (2019). The Common Partner of Several Methyltransferases TRMT112 Regulates the Expression of N6AMT1 Isoforms in Mammalian Cells. Biomolecules, 9 (9), 422. DOI: 10.3390/biom9090422.
5.2.
2019
Salmina, Kristine; Kurg, Reet; Krigerts, Jekabs; Erenpreisa, Jekaterina (2019). The topological relationship between ribogenesis, mRNA transcription/splicing and the tension of actin cytoskeletion. Biopolymers and Cell. National Academy of Sciences of Ukraine, 231−232. DOI: 10.7124/bc.0009F7.
1.1.
2018
Õunap, Kadri; Kurg, Kristiina; Võsa, Liisi; Maiväli, Ülo; Teras, Marina; Planken, Anu; Ustav, Mart; Kurg, Reet (2018). Antibody response against cancer‑testis antigens MAGEA4 and MAGEA10 in patients with melanoma. Oncology Letters, 16 (1), 211−2018. DOI: 10.3892/ol.2018.8684.
1.1.
2016
Kurg, Reet; Reinsalu, Olavi; Jagur, Sergei; Õunap, Kadri; Võsa, Liisi; Kasvandik, Sergo; Padari, Kärt; Gildemann, Kiira; Ustav, Mart (2016). Biochemical and proteomic characterization of retrovirus Gag based microparticles carrying melanoma antigens. Scientific Reports, 6 (29245), 1−11. DOI: 10.1038/srep29425.
1.1.
2015
Õunap, K.; Leetsi, L.; Matsoo, M.; Kurg, R. (2015). The Stability of Ribosome Biogenesis Factor WBSCR22 Is Regulated by Interaction with TRMT112 via Ubiquitin-Proteasome Pathway. PLoS ONE, 10 (7), e0133841. DOI: 10.1371/journal.pone.0133841.
1.1.
2015
Kivipõld, P.; Võsa, L.; Ustav, M.; Kurg, R. (2015). DAXX modulates human papillomavirus early gene expression and genome replication in U2OS cells. Virology Journal, 12, 104.10.1186/s12985-015-0335-z.
1.1.
2015
Sankovski, Eve; Karro, Kristiina; Sepp, Mari; Kurg, Reet; Ustav, Mart; Abroi, Aare (2015). Characterization of the nuclear matrix targeting sequence (NMTS) of the BPV1 E8/E2 protein - the shortest known NMTS. Nucleus, 289−300. DOI: 10.1080/19491034.2015.1074359.
1.1.
2013
Õunap, Kadri; Käsper, Ly; Kurg, Ants; Kurg, Reet (2013). The human WBSCR22 protein is involved in the biogenesis of the 40S ribosomal subunits in mammalian cells. PLoS ONE, 8 (9), nr e75686. DOI: 10.1371/journal.pone.0075686.
1.1.
2012
Võsa, L; Sudakov, A; Remm, M; Ustav, M; Kurg, R. (2012). Identification and analysis of papillomavirus E2 protein binding sites in the human genome. Journal of Virology, 86 (1), 348−357. DOI: 10.1128/JVI.05606-11.
1.1.
2012
Järving, R.; Lõokene, A.; Kurg, R.; Siimon, L.; Järving, I.; Samel, N. (2012). Activation of 11R-lipoxygenase is fully Ca(2+)-dependent and controlled by the phospholipid composition of the target membrane. Biochemistry, 51 (15), 3310−3320. DOI: 10.1021/bi201690z.
3.2.
2011
Kurg, R. (2011). The role of E2 proteins in papillomavirus DNA replication. In: Seligmann, H. (Ed.). DNA Replication - Current Advances (613−638).. Rijeka, Croatia: INTECH.
6.3.
2011
Kurg, Reet (2011). INEPO-l kohtuvad keskkonnahuvilised noored. Eesti Loodus, 8.
1.1.
2010
Kurg, R; Uusen, P; Võsa, L; Ustav, M (2010). Human papillomavirus E2 protein with single activation domain initiates HPV18 genome replication, but is not sufficient for long-term maintenance of virus genome. Virology, 408 (2), 159−166.10.1016/j.virol.2010.09.010.
1.1.
2009
Varvas, K.; Kurg, R.; Hansen, K.; Järving, R.; Järving, I.; Valmsen, K.; Lõhelaid, H.; Samel, N. (2009). Direct evidence of the cyclooxygenase pathway of prostaglandin synthesis in arthropods: Genetic and biochemical characterization of two crustacean cyclooxygenases. Insect Biochemistry and Molecular Biology, 39 (12), 851−860.
1.1.
2009
Kurg, R.; Uusen, P.; Sepp, T.; Sepp, M.; Abroi, A.; Ustav, M. (2009). Bovine papillomavirus type 1 E2 protein heterodimer is functional in papillomavirus DNA replication in vivo. Virology, 386 (2), 353−359. DOI: 10.1016/j.virol.2009.01.025.
5.1.
2008
Hansen, K.; Kurg, R.; Varvas, K.; Valmsen, K.; Järving, I.; Järving, R.; Samel, N. (2008). Cloning, expression and characterization of cyclooxygenase gene from amphipods. FEBS Journal: Joint Conference of the 33rd FEBS Congress/11th IUBMB Conference. Athens, GREECE, JUN 28-JUL 03, 2008. , 403. (275).
1.1.
2007
Denks, K.; Späeth, E.L.; Jõers, K.; Randoja, R.; Talpsep, T.; Ustav, M.; Kurg, R. (2007). Coinfection of Chlamydia trachomatis, Ureaplasma urealyticum and human papillomavirus among patients attending STD clinics in Estonia. Scandinavian Journal of Infectious Diseases, 39 (8), 714−718.
5.2.
2007
Hansen, K.; Kurg, R.; Varvas, K.; Järving, I.; Järving, R.; Valmsen, K.; Samel, N. (2007). Tsüklooksügenaas kirpvähilistest: kloneerimine, ekspresseerimine ja iseloomustamine [Cloning, expression and characterization of cyclooxygenase gene from amphipods]. XXX Eesti Keemiapäevad Teaduskonverentsi teesid: XXX Eesti Keemiapäevad Tartus 16. november 2007. Toim. Rinken, A. Tartu: Tartu Ülikooli Kirjastus, 30−31.
1.1.
2006
Kurg, R; Tekkel, Helena; Abroi, Aare; Ustav, Mart (2006). Characterizarion of the functional activities of the bovine papillomavirus type 1 E2 protein single-chain heterodimers. Journal of Virology, 80 (22), 11218−11225.
1.1.
2005
Kurg, R.; Sild, K.; Ilves, A.; Sepp, M.; Ustav, M. (2005). Association of bovine papillomavirus E2 protein with nuclear structures in vivo. Journal of Virology, 79 (16), 10528−10539.
1.1.
2004
Jarving, R.; Jarving, I.; Kurg, R.; Brash, AR.; Samel, N. (2004). On the evolutionary origin of cyclooxygenase (COX) isozymes - Characterization of marine invertebrate COX genes points to independent duplication events in vertebrate and invertebrate lineages. Journal of Biological Chemistry, 279 (14), 13624−13633.
1.1.
2001
Kivimae, S.; Allikas, A.; Kurg, R.; Ustav, M. (2001). Replication of a chimeric origin containing elements from Epstein-Barr virus ori P and bovine papillomavirus minimal origin. Virus Research, 75 (1), 1−11.
1.1.
2001
Allikas, A.; Ord, D.; Kurg, R.; Kivi, S.; Ustav, M. (2001). Roles of the hinge region and the DNA binding domain of the bovine papillomavirus type 1 E2 protein in initiation of DNA replication. Virus Research, 75 (2), 95−106.
1.1.
2001
Koljak, R.; Jarving, I.; Kurg, R.; Boeglin, WE.; Varvas, K.; Valmsen, K.; Ustav, M.; Brash, AR.; Samel, N. (2001). The basis of prostaglandin synthesis in coral - Molecular cloning and expression of a cyclooxygenase from the Arctic soft coral Gersemia fruticosa. Journal of Biological Chemistry, 276 (10), 7033−7040.
1.1.
2000
Kurg, R.; Langel, U.; Ustav, M. (2000). Inhibition of the bovine papillomavirus E2 protein activity by peptide nucleic acid. Virus Research, 66 (1), 39−50.
3.2.
2000
Kurg, R; Ustav, M. (2000). Update to: Monitoring and Purification of Proteins Using Bovine Papillomavirus E2 Epitope Tags. Lu,Q.; M.P. Weiner. Cloning and Expression Vectors for Protein Studies (Chapter 27). . Weiner: Eaton Publishing Co.
1.1.
1999
Abou-Zahr, F.; Bejjani, B.; Kruyt, FAE.; Kurg, R.; Bacino, C.; Shapira, SK.; Youssoufian, H. (1999). Normal expression of the Fanconi anemia proteins FAA and FAC and sensitivity to mitomycin C in two patients with Seckel syndrome. American Journal of Medical Genetics, 83 (5), 388−391.
1.1.
1999
Kurg, R.; Parik, J.; Juronen, E.; Sedman, T.; Abroi, A.; Liiv, I.; Langel, U.; Ustav, M. (1999). Effect of bovine papillomavirus E2 protein-specific monoclonal antibodies on papillomavirus DNA replication. Journal of Virology, 73 (6), 4670−4677.
1.1.
1996
Abroi, A.; Kurg, R.; Ustav, M. (1996). Transcriptional and replicational activation functions in the bovine papillomavirus type 1 E2 protein are encoded by different structural determinants. Journal of Virology, 70 (9), 6169−6179.

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15.07.2021