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Olen nõus

Ruth Mikelsaar

https://www.etis.ee/CV/Ruth_Mikelsaar/est
11.04.1941
737 4215
ruth.mikelsaar@ut.ee

Teenistuskäik

Töökohad ja ametid
2013–...   
Tartu Ülikool, Arstiteaduskond, Biomeditsiini instituut, Inimese bioloogia ja geneetika õppetool, Vanemteadur (0,50)
01.01.1993–...   
TÜ ÜMPI inimese geneetika labori juhataja
01.02.2008–31.01.2013   
Tartu Ülikool, Arstiteaduskond, Üld- ja molekulaarpatoloogia instituut, meditsiinigeneetika dotsent (0,75)
01.02.2008–31.01.2013   
Tartu Ülikool, Arstiteaduskond, Üld- ja molekulaarpatoloogia instituut, meditsiinigeneetika vanemteadur (0,25)
1997–2008   
Tartu Ülikool, Arstiteaduskond, Üld- ja molekulaarpatoloogia instituut, Inimese bioloogia ja geneetika õppetool, Dotsent (1,00)
01.01.1993–31.12.1998   
TÜ ÜMPI vanemteadur
01.01.1988–31.12.1990   
Vabariiklik Meditsiinigeneetika Keskus, meditsiinigeneetik
01.01.1981–31.12.1987   
Tartu Ülikool Lastekliinik, meditsiinigeneetik
01.01.1981–31.12.1993   
TÜ ÜMPI nooremteadur, teadur
01.01.1966–31.12.1981   
-Tartu Vabariiklik Psühhoneuroloogiahaigla, laborijuhataja
 
 
Haridustee
2000–2000   
täiendus-koostöö Helsingi Ühendlaboratooriumi molek-tsütogeneetika osak
1998–1998   
Dresdeni Ülikool, Tehnika Instituut, Kliinilise geneetika osak
1993–1993   
teadustöö, Lüübeki Meditsiini Ülikool,geneetika osak.
1989–1989   
Vilniuse Meditsiinigeneetika Keskus
1984–1984   
Vilniuse Meditsiinigeneetika Keskus
1977–1977   
Moskva Arstide Täiendusinstituut, meditsiinigeneetika
1974–1974   
Moskva Arstide Täiendusinstituut, meditsiinigeneetika
1959–1966   
lõpetanud Tartu Ülikooli arstiteaduskonna raviosakonna, arst
 
 
Teadusorganisatsiooniline ja -administratiivne tegevus
2005−...   
Soome Akadeemia ekspert
2005−...   
European Science Foundation liige-ekspert
2000−...   
Eesti Inimesegeneetikute Selts; asutajaliige, 2000-2004 -juhatuse liige
1995−...   
Euroopa Tsütogeneetikute Assotsiatsioon, liige
1994−...   
Rahvusvaheline Vastsündinute Skriiningu Selts
1994−...   
Euroopa Inimesegeneetika Selts, liige
1993−...   
TÜ ÜMPI inimese geneetika labori juhataja. Juhendanud: 3 doktoritööd, 1 magistritöö, 3 bakalaureusetööd
1998−2013   
Meditsiinigeneetika residentuuri eksamikomisjoni liige
1998−2013   
Meditsiinigeneetika residentuuri juhendaja
1996−1999   
TÜ arstiteaduskonna nõukogu liige
 
 
Loometöö
Monograafia: Ruth Mikelsaar "Kromosoomihaigused" Atlex, 2001,137 lk. .
Saadud uurimistoetused (grandihoidjana):
1) ETF grant 1095 "Kaasasündinud hüpotüreoosi epidemioloogia ja geneetika Eestis" (1994-1996)
2) ETF grant 3025 "Geneetiline, epidemioloogiline ja preventiivne uurimus vaimse alaarengu kohta" (1997-2000)
3) ETF 5086 "Vaimse alaarengu ja teiste patoloogiliste seisundite tekkepõhjuste uurimine molekulaarsete ja tsütogeneetiliste meetoditega" (2003-2006)
Toetuste (põhitäitjana):
1) SF0182560s03 "Geneetilised ja rakulised haiguste põhjused, rakkude diferentseerumine ja tüvirakud teraapias" (2003-2007)
2) SF0180096s08 "Inimese fetaalsete ja embrüonaalsete tüvirakkude diferentseerumine neuraalses suunas ja uute immuunmarkerite loomine" (2008-2013)
3) LARMP 12232 "Projekti BOSS (BOVINE SPERM SEXING) raames polü- ja monoklonaalsete antikehade loomine pulli X- ja Y-kromosoomi kandvate spermide vastu" (2012-2014) .

Kvalifikatsioon

Teaduskraadid
Ruth Mikelsaar, doktorikraad, 1993, (juh) Ruth Mikelsaar, Etiological factors of diseases in genetically consulted children and newborn screening, Tartu Ülikool.
Ruth Mikelsaar, doktorikraad, 1980, (juh) Ruth Mikelsaar, Dermatoglyphics in patients with schizophrenia, neurosis and oligophrenia (in Russ.), NSVL Meditsiiniteaduste Akadeemia Meditsiinigeneetika Instituut, Moskva.
 
 
Teaduspreemiad ja tunnustused
2013, Ruth Mikelsaar, I preemia - suuline ettekanne, TÜ arstiteaduskonna aastapäeva teaduskonverents
2011, Ruth Mikelsaar, Tartu Ülikooli tänukiri
2011, Ruth Mikelsaar, Tartu Ülikooli väike medal
2005, Ruth Mikelsaar, III preemia - stendiettekanne, TÜ arstiteaduskonna aastakonverents
2001, Ruth Mikelsaar, I preemia - stendiettekanne, TÜ arstiteaduskonna aastakonverents
1998, Ruth Mikelsaar, I preemia - stendiettekanne, TÜ arstiteaduskonna aastakonverents
 
 
Teadustöö põhisuunad
ETIS KLASSIFIKAATOR: 3. Terviseuuringud; 3.1. Biomeditsiin; TÄPSUSTUS: 1) Inimese pärilikud haigused, 2) Sõeluuringud, 3) Dermatoglüüfika, 4) Inimese kromosoomide erinevuse uurimine normis ja haigetel (vaimne alaareng jt.), 5) Meeste/ naiste infertiilsuse geneetiliste põhjuste uurimine
 
 
Lisainfo
Kadi Varb, bakalaureusetöö, 2003, (juh) Ruth Mikelsaar, Mare Remm, Abielupaaride infertiilsuse tsütogeneetilised põhjused, Tartu Meditsiinikool
Marje Johanson, bakalaureusetöö 2007, (juh) Anne Selart, Ruth Mikelsaar, Keskkonna tegurid - kas üks meeste viljatuse põhjuseid? Tartu Ülikool, Matemaatika-informaatika teaduskond
Helerin Margus, bakalaureusetöö, 2009, (juh) Ruth Mikelsaar, Sulev Ingerpuu. Meeste hüpogonadismi tsütogeneetiline uurimine. Tartu Ülikool, Loodus- ja Tehnoloogia teaduskond
1998 - 2012. Juhendanud 13 meditsiinigeneetika arst-residenti tsütogeneetika ja sündromoloogia õppes Tartu Ülikooli arstiteaduskonna inimese bioloogia ja geneetika õppetoolis

Juhendatud väitekirjad

Publikatsioonid

Klass
Aasta
Publikatsioon
 
1.1.
2014
Mikelsaar, Ruth; Paves, Heiti; Org, Katrin; Mikelsaar, A.-V. (2014). Chromosome variant 1qh- and its influence on the 3D organization of chromosome 1 heterochromatin in interphase nucleus of patients with endometriosis. Journal of Genetics, 93 (1), 219−223.
5.2.
2014
Mikelsaar, A-V.; Vorobjova, A.; Saag, M.; Mikelsaar, Ruth; Juronen, E. (2014). Expression of mucins and glutathione-S-transferases in dental stem cells isolated from human third molar. Cytochemical study. Abstract of the 12th Annual Meeting of ISSCR (International Society for Stem Cell Research), Vancouver(Canada), 2014. F-L-4021.
5.2.
2013
Mikelsaar, Ruth; Paves, H.; Org, K.; Mikelsaar, A.-V. (2013). Kromosoomvariant 1qh- ja 1. kromosoomi konstitutiivse heterokromatiini 3D-organisatsioon interfaasituumas endometrioosihaigetel (I auhind). Eesti Arst . 18−18. (92,Lisa 2).
5.2.
2013
Mikelsaar, A.-V.; Masso, R.; Masso, M.; Sünter, A.; Mikelsaar, R.; Juronen, E. (2013). Titiin mittelihasrakkudes. Evolutsiooniline analüüs. Eesti Arst, 92. 37−37. (Lisa 2).
5.2.
2013
Mikelsaar, Ruth; Paves, Heiti (2013). Altered intra-nuclear organization of heterochromatin of chromosome 1 in interphase nuclei of patients with endometriosis by 3D-FISH. Europ J Human Genetics, 21: European Human Genetics Conference 2013, Paris. Nature Publishing Group, 589.
1.1.
2012
Mikelsaar, A.-V.; Sünter, A.; Mikelsaar, R.; Toomik, P.; Kõiveer, A.; Mikelsaar, I.; Juronen, E. (2012). Epitope of titin a-band-specific monoclonal antibody Tit1 5 H1.1 is highly conserved in several Fn3 domains of the titin molecule. Centriole staining in human, mouse and zebrafish cells. Cell Division, 7, Art No 21.10.1186/1747-1028-7-21.
1.1.
2012
Mikelsaar, Ruth; Nelis, M.; Kurg, A.; Zilina, O.; Korrovitš, P.; Rätsep, R.; Väli, M. (2012). Balanced reciprocal translocation t(5;13)(q33;q12) and 9q31.1 microduplication in a man suffering from infertility and pollinosis. Journal of Applied Genetics, 53 (1), 93−97. DOI: 10.1007/s13353-011-0078-5.
5.2.
2012
Mikelsaar, A.-V.; Sünter, A.; Mikelsaar, Ruth; Toomik, P.; Mikelsaar, I.; Juronen, E. (2012). Evolutionary aspects of centriole associated proteins. Europ J Human Genetics: European Human Genetics Conference 2012 in conj. with the European Meeting on Psychosocial Aspects of Genetics, Nürnberg. 251.
5.2.
2012
Mikelsaar, R.; Nelis, M.; Kurg, A.; Žilina, O.; Bartsch, O.; Punab, M.; Korrovitš, P.; Rätsep, R (2012). Genomic imbalances in infertile men detected by array analysis. Europ J Human Genetics: European Human Genetics Conf. 2012 in conjunction with the European Meeting on Psychosocial Aspects of Genetics, Nürnberg. , 119−120.
1.1.
2011
Mikelsaar, R.; Lissitsina, J.; Bartsch, O. (2011). Small supernumerary marker chromosome (sSMC) derived from chromosome 22 in an infertile man with hypogonadotropic hypogonadism. Journal of Applied Genetics, 52, 331−334.10.1007/s13353-011-0041-5.
3.1.
2011
Mikelsaar, Aavo-Valdur; Sünter, Alar; Toomik, Peeter; Mikelsaar, Ruth; Juronen, Erkki (2011). New data on the centrosome proteins. Chromosome Research. The Biology of Chromatin and Chromosomes, 19: 8th European Cytogenetics Conference, Altândega Congress & Exhibition Centre, Portugal, 2-5. july 2011. Springer, S199. (Supplement 1).
5.2.
2011
Mikelsaar, Ruth.; Nelis, M.; Bartsch, O.; Punab, M. (2011). Karyotyping and array analysis in the detection of genomic changes in infertile men. Chromosome Research: 8th European Cytogenetics Conference, Altàndega Congress& Exhibition Centre, Porto(Portugal), 2-5.July 2011. Springer, S89−S90.
1.1.
2010
Mikelsaar, R.; Lissitsina, J.; Ausmees, K.; Punab, M.; Korrovits, P.; Vaidla, E. (2010). Alpha-1 antitrypsin phenotypes in patients with Klinefelter's syndrome. Journal of Genetics, 89 (4), 485−488.
1.1.
2010
Mikelsaar, A-V.; Sünter, A.; Toomik, P.; Mikelsaar, R.; Kalev, I.; Kõiveer, A.; Piirsoo, A.; Karpson, K.; Juronen, E. (2010). Titin A-band-specific Monoclonal Antibody Tit1 5H1.1. Cellular Titin As a Centriolar Protein in Non-muscle Cells. Hybridoma, 29 (5), 391−401. DOI: 10.1089/hyb.2009.0116.
5.2.
2010
Mikelsaar, R.; Lissitsina, J.; Ausmees, K.; Punab, M.; Korrovits, P. (2010). New chromosome aberrations in male hypogonadism. Europ J Human Genetics, 18: European Human Genetics Conference 2010 in conj. with the European Meeting on Psychosocial Aspects of Genetics, Gothenburg. Nature Publishing Group, 116. (1).
5.2.
2010
Lamp, M.; Kaljurand, K.: Mikelsaar, R. (2010). Unusual case of bilateral iridocorneal endothelial syndrome with extraocular anomalies. European J of Human Genetics: European Human Genetics Conference 2010 in conjuction with European Meeting on Psychosocial Aspects of Genetics.Gothenburg,2010. Nature Publishing Group, 80−81.
5.2.
2010
Mikelsaar, A.-V.; Sünter, A.; Toomik, P.; Mikelsaar, R.; Juronen, E. (2010). Titin or a titin-like protein as a human centriolar protein? European Journal of Human Genetics, Supplement 1: European Human Genetics Conference 2010 in conjuction with European Meeting on Psychosocial Aspects of Genetics. Swedish Exhibition & Converence Centre: Nature Publishing Group, 109. (18).
5.1.
2009
Vaidla, E.; Lissitsina, J.; Margus, H.; Ausmees, K.; Punab, M.; Korrovits, P.; Mikelsaar, Ruth. (2009). Association of Klinefelter syndrome with alpha-1 antitrypsin. Chromosome Research, 17(Suppl): Abstract of 7th European Cytogenetics Conference, Stockholm. S63−63.
5.1.
2009
Mikelsaar, R; Margus, H; Korrovits, P. (2009). Chromosomal study in male infertility: survey and a case with unusual reciprocal translocation t(5;13)(q35;q14). Chromosome Research, 17: Abstract of 7th Cytogenetics Conference, Stockholm. S60−60.
5.1.
2009
Mikelsaar, A.-V. ; Sünter, A.; Toomik, P.; Karpson, K. ; Mikelsaar, R.; Juronen, E.. (2009). The subcellular localisation of Ku80 during mitotic cycle - an immunocytochemical analysis using anti Ku80 Mab F10H2.B3. Chromosome Research, 17: 7th European Cytogenetics Conference, Stockholm, 4-7 July 2009. Ed. Herbert Macgregor. Dordrecht, The Netherlands/Norwel,MA,USA: Springer Heidelberg, S172−S172.
5.2.
2009
Mikelsaar, Ruth; Margus, H.; Lissitsina, J.; Korrovitš, P. (2009). Uusi aspekte meeste viljatuse kohta. Eesti Arst. 611. (9).
5.2.
2009
Lissitsina, J.; Mikelsaar, Ruth; Punab, M. (2009). Uus meeste viljatuse kromosomaalne põhjus: lisa inv dup(22)(q11.1). Eesti Arst. 598− . (9).
5.2.
2009
Mikelsaar, A.-V.; Sünter, A.; Toomik, P.; Mikelsaar, R.; Kalev, I.; Vaidla, E.; Kõiver, A.; Piirsoo, A.; Juronen, E. (2009). Tsellulaarne titiin. Uued monoklonaalsed antikehad Tit1 5H1.1 ja Tit2 2E8.1. Eesti Arst. 608−609. (9).
5.2.
2008
Mikelsaar, R.; Molder, H.; Bartsch, O.; Punab, M. (2008). Array CGH analysis (two novel deletions) in pigment dispersion syndrome. European Journal of Human Genetics, 16(2): European Human Genetics Conf. 2008, Barcelona. 160.
1.1.
2007
Mikelsaar, R.; Molder, H.; Bartsch, O.; Punab, M. (2007). Two Novel Deletions (Array CGH Findings) in Pigment Dispersion Syndrome. Ophthalmic Genetics, 28 (4), 216−219.
5.1.
2007
Mikelsaar, Ruth; Lissitsina, J.; Punab, M. (2007). Chromosomes in fertility problems. Chromosome Research, 15: 6th European Cytogenetics Conference, JUL 07-10, 2007. 115.
1.1.
2006
Lissitsina, J.; Mikelsaar, R.; Punab, M. (2006). Cytogenetic analyses in infertile men. Archives of Andrology, 52 (2), 91−95.
1.3.
2006
Lissitsina, J.; Mikelsaar, R.; Punab, M. (2006). Kromosoomianomaaliad ja kromosoomivariandid infertiilsetel meestel. Eesti Arst, 85 (2), 84−89.
5.1.
2006
Mikelsaar, Ruth; Lissitsina, Jelena; Punab, Margus (2006). Cytogenetic analyses of families with fertility problems. European Journal of Human Genetics, 14, 171−171.
5.2.
2006
Lissitsina, J.; Mikelsaar, R.; Punab, M. (2006). Kromosoomihaigused ja varikotseele meeste viljatuse põhjustena. Eesti Arst, 85. 649−650.
5.2.
2006
Mikelsaar, Ruth; Lissitsina, Jelena; Punab, Margus (2006). Cytogenetic study of couples infertile. Laboratorine Medicina, 29 (1), S36.
5.1.
2005
Lissitsina, Jelena; Punab, Margus; Mikelsaar, Ruth (2005). Chromosomal analyses in males with azoo- and oligospermia. Chromosome Research, 13, 71−72.
5.2.
2005
Mikelsaar, R.; Pauklin, M.; Lissitsina, J.; Punab, M. (2005). Infertiilsete meeste tsütogeneetiline uurimine: tulemused ja t(7;16)(q21.2;p13.3) patsiendil oligospermiaga. Eesti Arst, 84 (9), 674−675.
1.3.
2004
Varb, K.; Mikelsaar, Ruth; Lissitsina, J. (2004). Abielupaaride infertiilsuse tsütogeneetilised põhjused. Eesti Arst, 83 (1), 3−8.
5.1.
2004
Mikelsaar, Ruth; Roomets, Eva; Pihlau, Helju (2004). New syndrome - chromosome 19q distal deletion syndrome. European Journal of Human Genetics, 12, 136.
5.2.
2004
Mikelsaar, R.; Roomets, E.; Pihlau, E. (2004). Uus kromosoomihaigus - 19q distaalne deletsioon. Eesti Arst, 83. 619.
5.1.
2003
Mikelsaar, Ruth; Vessel, Epp; Mölder, Hillar; Punab, Margus (2003). Translocation t(10;15) in a man with pigment dispersion syndrome and infertility. European Journal of Human Genetics, 11, 303.
5.2.
2003
Lissitsina, J.; Mikelsaar, R.; Varb, K.; Punab, M. (2003). Infertiilsete meeste tsütogeneetiline uurimine. Eesti Arst, 82. , 637.
5.2.
2003
Lissitsina, J.; Mikelsaar, Ruth; Varb, K.; Punab, M. (2003). Cytogenetic study in infertile men. Annales De Génétique. 185.
1.1.
2002
Mikelsaar, RV.; Muru, K.; Kulla, A.; Suvari, A. (2002). Psoriasis vulgaris in a male with partial deletion 18p. American Journal of Medical Genetics, 108 (3), 252−253.
5.1.
2002
Lissitsina, J.; Mikelsaar, R.; Varb, K.; Punab, M. (2002). Chromosomal analyses in infertile men. European Journal of Human Genetics, 10, 160−160.
5.1.
2002
Mikelsaar, Ruth; Muru, Kai; Varb, Kadi; Kulla, Andres; Süvari, Anneli (2002). Deletion 18p in a Patient with Psoriasis Vulgaris. European Journal of Human Genetics, 10, 151.
5.2.
2002
Varb, K.; Mikelsaar, R.; Lissitsina, J.; Punab, M. (2002). Lastetute abielupaaaride tsütogeneetiline uurimine. Eesti Arst, 81 (9), 593.
1.2.
2001
Mikelsaar, R.; Varb, K.; Suvari, A.; Schinzel, A. (2001). Mosaic terminal del(19)(q13.33:) in a girl with seizures and mental retardation. Journal of Medical Genetics, 38 (1), e2−e5. DOI: 10.1136/jmg.38.1.e2.
2.2.
2001
Mikelsaar, Ruth (2001). Kromosoomihaigused. Tartu: Atlex.
5.1.
2001
Mikelsaar, Ruth; Salo, Armi; Varb, Kadi; Süvari, Anneli; Muru, Kai; Teek, Rita. (2001). Chromosome analysis in mental retardation. European Journal of Human Genetics, 9, 145.
5.2.
2001
Lissitsina, Jelena; Mikelsaar, Ruth; Varb, Kadi; Timberg, Gennadi; Punab, Margus (2001). Two cases of extra marker chromosome in infertile men. European Journal of Human Genetics, 9, 148.
5.1.
2000
Mikelsaar, R.; Varb, K.; Lissitsina, J.; Mikelsaar, A.-V. (2000). Extra marker chromosome in an infertile man. European Journal of Human Genetics, 8. 92.
1.1.
1999
Mikelsaar, RV.; Viikmaa, M. (1999). Neonatal thyroid-stimulating hormone screening as an indirect method for the assessment of iodine deficiency in Estonia. Hormone Research, 52 (6), 284−286.
5.1.
1999
Toublanc, J.-E.; Ratajczak, R.; Stoeva, I.; Tsukerman, G.; Mikelsaar, R. (1999). Epidemiology of Congenital Hypothyroidism, Its Relation with Iodine Deficiency in Eastern Europe. Hormone Research, 51(2): 38th Annual Meeting of the European Society for Paediatric Endocrinology (ESPE); Warsaw, Poland; 29 August - 1 September, 1999. _EditorsAbbr Romer, T. 3.
5.2.
1999
Mikelsaar, R.; Varb, K.; Süvari, A. (1999). Mosaic deletion del(19)(q13.33qter) in a girl with epilepsy and mental retardation. European Journal of Human Genetics, 7(1). 76.
1.1.
1998
Mikelsaar, RV.; Zordania, R.; Viikmaa, M.; Kudrjavtseva, G. (1998). Neonatal screening for congenital hypothyroidism in Estonia. Journal of Medical Screening, 5 (1), 20−21.
1.3.
1998
Mikelsaar, Ruth; Kudrjavtseva, G.; Viikmaa, M. (1998). Kaasasündinud hüpotüreoosi sõeluuring Eestis. Eesti Arst, 77 (3), 195−198.
5.1.
1998
Mikelsaar, AV.; Beckman, L.; Tasa, G.; Parlist, P.; Mikelsaar, R. (1998). The frequency of hemochromatosis mutation C282Y in Estonian population. European Journal of Human Genetics, 6, 106−106.
1.1.
1996
Mikelsaar, RV.; Lurie, IW.; Ilus, TE. (1996). 'Pure'' partial trisomy 4q25-qter owing to a de novo 4;22 translocation. Journal of Medical Genetics, 33 (4), 344−345.
1.1.
1994
Robinson, W.; Binkert, F.; Schinzel, A.; Basaran, S.; Mikelsaar, R. (1994). Multiple origins of x-chromosome tetrasomy. Journal of Medical Genetics, 31 (5), 424−425.
1.3.
1993
Mikelsaar, Ruth (1993). Laste geneetiline uurimine Eestis. Eesti Arst, 72 (1), 4−6.
2.3.
1993
Mikelsaar, Ruth (1993). Etiological Factors of Diseases in Genetically Consulted Children and Newborn Screening. (Doktoritöö, Tartu Ülikool, Arstiteaduskond). Tartu: Tartu University Press.
1.1.
1992
Mikelsaar, RVA.; Lurie, IW. (1992). Atypical case of aarskog syndrome. Journal of Medical Genetics, 29 (5), 349−350.
1.2.
1992
Mikelsaar, R.; Mikelsaar, A.-V.; Kudrjavtseva, G. (1992). Newborn Screening for Congenital Hypothyroidism in Estonia. Infant Screening, 15 (4), 17−18.
1.3.
1991
Mikelsaar, R. (1991). The Allunion conference - Prenatal and Neonatal Screening for Congenital and Genetic Pathology - in Kharkow 22-23.11.1990. Eesti Arst, 140−141.
3.2.
1991
Mikelsaar, R. (1991). Neonatal Screening for Congenital Hypothyroidism. Genetics and Prophylaxis of Inherited diseases (101−103).. Vilnius: Mokslas.
1.3.
1990
Mikelsaar, Ruth (1990). Kaasasündinud hüpotüreoosi varane diagnoosimine. Eesti Arst, 5, 339−342.
1.3.
1988
Ilus, T.; Mikelsaar, R. (1988). Edwardsi sündroom e. 18. kromosoomi trisoomia. Nõukogude Eesti Tervishoid, 4, 245−148.
3.2.
1988
Mikelsaar, R.; Vasar, M. (1988). Rubinstein-Taybi Syndrome. In: Proceedings of the University of Tartu "Trudõ po meditsine" (143−148).. Tartu: Tartu Ülikooli Kirjastus.
1.1.
1987
Mikelsaar, RV.; Ilus, TA.; Lurie, IW. (1987). Distal trisomy 14q. Journal of Medical Genetics, 24 (6), 380−381.
3.5.
1987
Mikelsaar, R. (1987). Medico-genetic counseling of patients with mental and psychomotor retardation in Children Hospital. Genetic studies in Soviet Estonia (66−69).. Tallinn: Eesti NSV Teaduste Akadeemia.
2.3.
1980
Mikelsaar, RV-A. (1980). Dermatoglyphics in patients with schizophrenia, neurosis and oligophrenia (Cand.dissert). (Doktoritöö, Tartu Ülikool, Arstiteaduskond). Tartu: Tartu University Press.
3.2.
1977
Mikelsaar, R. (1977). Dermatoglyphics of fingers and palms in neurotics. Trudõ po meditsine XXXIV (110−120).. Tartu: Tartu State University.
1.1.
1976
Kaosaar, ME.; Mikelsaar, AVN.; Talvik, TA.; Mikelsaar, RVA. (1976). Case of trisomy for short arm of chromosome no9 (+9(p)). Human Genetics, 34 (1), 77−80.
1.1.
1974
Horn, AV.; Mikelsaar, RVA. (1974). Dermal patterns in normal Estonians. Human Heredity, 24, 488−495.
1.1.
1973
Mikelsaar, AV.; Lazjuk, GJ.; Lurie, JW.; Tuur, S.; Kaosaar, ME.; Mikelsaar, R.; Loolaid, VE. (1973). A 4p-syndrome. A case report. Humangenetik, 19 (3), 345−347.
1.1.
1973
Talvik, T.; Mikelsaar, AV.; Mikelsaar, R.; Kaosaar, M.; Tuur, S. (1973). Inherited translocations in 2 families (t(14q+ - 10q-) and t(13q- - 21q+)). Humangenetik, 19, 215−226.
1.1.
1972
Talvik, TA.; Mikelsaar, RV.; Mikelsaar, AN. (1972). Family reciprocal translocation between c-group chromosome and d-group chromosome[46, t(cq- - dq+)]. Genetika, 8 (5), 123.
1.3.
1972
Mikelsaar, R. (1972). Dematoglüüfide uurimise tähtsus meditsiinilises geneetikas. Nõukogude Eesti Tervishoid, 3, 198−201.
1.1.
1971
Talvik, TA.; Mikelsaar, A-VN.; Mikelsaar, RV-A.; Kask, VA. (1971). A Ring Heterosoma (46,XXr or 46,XYr) in a 2,5 Year Old Girl. Genetika (Moskva), 7, 136−142.
1.1.
1971
Mikelsaar, A-V.N; Naidionova, MM.; Talvik, T.A.; Mikelsaar, Ruth V.-A. Kaselaid VL; Zucker, EI; Grinberg, KN. (1971). XX/X0 Mosaicism in a new-born female infant with an atypical phenotype. Genetika (Moskva), 2, 152−160.
1.1.
1971
Mikelsaar, RV-A. (1971). Characteristic Features of Dermatoglyphics in Cases of Schizophrenia. Genetika (Moskva), 3, 139−146.
1.1.
1971
Mikelsaar, A-VN.; Blumina, MG.; Kuznetsova, LI.; Mikelsaar, RV-A.; Lurie, IV. (1971). A Double Chromosome Aberration 47,XX,21+/47,XXp-q-,21+ in a Girl with Symptoms of Down's and Turner's Syndromes. Genetika (Moskva), 5, 156−161.
1.1.
1971
Mikelsaar, A-VN.; Blumina, MG.; Kuznetsova, LI.; Mikelsaar, RV. (1971). Children with an XYY sex chromosome set. Genetika (Moskva), 8, 156−165.
3.2.
1971
Mikelsaar, R. (1971). Peculiarities of Dermatoglyphics in Schizophrenia. Problems of Medical Genetics and Human Genetics (141−143).. Minsk: Nauka i Tehnika.
3.2.
1968
Mikelsaar, R.;Tamm, EN. (1968). Combination of Klinefelter's syndrome and Schizophrenia. Proceedings of the University of Tartu "Research in medicine" (75−79).. TÜ Kirjastus.
6.09.2021

Ruth Mikelsaar

https://www.etis.ee/CV/Ruth_Mikelsaar/eng
11.04.1941
737 4215
ruth.mikelsaar@ut.ee

Career

Institutions and positions
2013–...   
University of Tartu, Faculty of Medicine, Institute of Biomedicine, Chair of Human Biology and Genetics, Senior Researcher (0,50)
01.01.1993–...   
University of Tartu, IGMP, head of Human Genetics Lab
01.02.2008–31.01.2013   
University of Tartu, Faculty of Medicine, Departement of General and Molecular Pathology, Associate Professor in Medical Genetics (0,75)
01.02.2008–31.01.2013   
University of Tartu, Faculty of Medicine, Departement of General and Molecular Pathology, Senior Research Fellow in Medical Genetics (0,25)
1997–2008   
University of Tartu, Faculty of Medicine, Departement of General and Molecular Pathology, Chair of Human Biology and Genetics, Associate Professor (1,00)
01.01.1993–31.12.1998   
University of Tartu, IGMP senior researcher
01.01.1988–31.12.1990   
Republic Medical Genetics Center, medical geneticist
01.01.1981–31.12.1987   
University of Tartu Children Hospital, medical geneticist
01.01.1981–31.12.1993   
University of Tartu, IGMP researcher
01.01.1966–31.12.1981   
Tartu Republic Psychoneurological Hospital, head of laboratory
 
 
Education
2000–2000   
studium-collabor.Helsinki Jointed Laboratories, dept.of molecular and cytogenetics
1998–1998   
University of Dresden, Technical Institute, dept. of clinical genetics
1993–1993   
studium-collabor. Medical University of Luebeck (Germany), dept. of genetics
1989–1989   
Vilnius Medical Genetics Centre
1984–1984   
Vilnius Medical Genetics Centre
1977–1977   
Institute of Advanced Training Courses, University of Moscow, medical genetics
1974–1974   
Institute of Advanced Training Courses, University of Moscow, medical genetics
1959–1966   
University of Tartu, Faculty of Medicine, physician
 
 
R&D related managerial and administrative work
2005−...   
Finnish Academy expert
2005−...   
European Science Foundation expert-member
2000−...   
Estonian Society of Human Genetics; foundation member, 2000-2004 -member of the council
1995−...   
European Cytogeneticists Association
1994−...   
International Society of Neonatal Screening
1994−...   
European Society of Human Genetics
1993−...   
Head of Human Genetics Lab. Supervisor of 3 doctor theses, 1 magister and 3 bachelor works
1998−2013   
Member of the exams-commission of the residency in medical genetics
1998−2013   
Supervisor of residents in medical genetics
1996−1999   
member of the Council of the Faculty of Medicine, the University of Tartu
 
 
Creative work
Monograph "Chromosomal disorders" Ruth Mikelsaar, Atlex, 2001, pp.137 .
Principal investigator of Estonian Science Foundation grants:
1) Grant 1095 "Epidemiology and genetics of congenital hypothyroidism in Estonia" (1994-1996)
2) Grant 3025 "Genetic, epidemiological and preventive study of mental retardation" (1997-2000)
3) Grant 5086 "Studies of causes of mental retardation and other conditions using molecular and cytogenetic methods" (2003-2006)
Main investigator:
1) Profect SF0182560s03 "Genetic and cellular causes of diseases, cell differentiation and stem cells in therapy" (2003-2007)
2) Project SF0180096s08 "Differentiation of human fetal neural and embryonic stem cells to neural cell lineages and development of new immunomarkers" (2008-2013)
3) LARMP 12232 "Development of the poly- and monoclonal antibodies against the bovine sperms carrying X- and/or Y-chromosome within the project BOSS (BOVINE SPERM SEXING)" (2012-2014) .

Qualifications

Academic degrees
Ruth Mikelsaar, Doctor's Degree, 1993, (sup) Ruth Mikelsaar, Etiological factors of diseases in genetically consulted children and newborn screening, University of Tartu.
Ruth Mikelsaar, Doctor's Degree, 1980, (sup) Ruth Mikelsaar, Dermatoglyphics in patients with schizophrenia, neurosis and oligophrenia (in Russ.), Academy of Medical Sciences of U.S.S.R., Institute of Medical Genetics, Moscow.
 
 
Honours & awards
2013, Ruth Mikelsaar, The I prize among oral presentations on the annual conference of the Medical faculty, University of Tartu
2011, Ruth Mikelsaar, Letter of Thanks from the University of Tartu
2011, Ruth Mikelsaar, Medal from the University of Tartu
2005, Ruth Mikelsaar, The III prize in poster session on the annual conference of the Medical faculty, University of Tartu
2001, Ruth Mikelsaar, The I prize in poster session on the annual conference of the Medical Faculty, University of Tartu
1998, Ruth Mikelsaar, The I prize in poster session on the annual conference of the Medical Faculty, University of Tartu
 
 
Fields of research
ETIS CLASSIFICATION: 3. Health; 3.1. Biomedicine; SPECIFICATION: 1) Genetic diseases, 2) Screening, 3) Dermatoglyphics, 4) Cytogenetics in norm and in diseases (mental retardation etc.), 5) Genetic causes (cytogenetics etc.) in male/female infertility
 
 
Additional information
Kadi Varb, Bachelor work, 2003, (sup) Ruth Mikelsaar, Mare Remm, Cytogenetic causes of infertile couples, Medical School of Tartu
Marje Johanson, Bachelor work 2007, (sup) Anne Selart, Ruth Mikelsaar, Environmental factors - are they cause of male infertility? University of Tartu, Faculty of Mathematics and Informatics
Helerin Margus, Bachelor work, 2009, (sup) Ruth Mikelsaar, Sulev Ingerpuu, Cutogenetic study of male hypogonadism, University of Tartu, Faculty of Science and Technology
1998 -2012. Supervisor of 13 physicians-residents of medical genetics in cytogenetics and syndromology cycle at the Chair of Human Biology and Genetics, Medical Faculty, University of Tartu

Supervised dissertations

Publications

Category
Year
Publication
 
1.1.
2014
Mikelsaar, Ruth; Paves, Heiti; Org, Katrin; Mikelsaar, A.-V. (2014). Chromosome variant 1qh- and its influence on the 3D organization of chromosome 1 heterochromatin in interphase nucleus of patients with endometriosis. Journal of Genetics, 93 (1), 219−223.
5.2.
2014
Mikelsaar, A-V.; Vorobjova, A.; Saag, M.; Mikelsaar, Ruth; Juronen, E. (2014). Expression of mucins and glutathione-S-transferases in dental stem cells isolated from human third molar. Cytochemical study. Abstract of the 12th Annual Meeting of ISSCR (International Society for Stem Cell Research), Vancouver(Canada), 2014. F-L-4021.
5.2.
2013
Mikelsaar, Ruth; Paves, H.; Org, K.; Mikelsaar, A.-V. (2013). Kromosoomvariant 1qh- ja 1. kromosoomi konstitutiivse heterokromatiini 3D-organisatsioon interfaasituumas endometrioosihaigetel (I auhind). Eesti Arst . 18−18. (92,Lisa 2).
5.2.
2013
Mikelsaar, A.-V.; Masso, R.; Masso, M.; Sünter, A.; Mikelsaar, R.; Juronen, E. (2013). Titiin mittelihasrakkudes. Evolutsiooniline analüüs. Eesti Arst, 92. 37−37. (Lisa 2).
5.2.
2013
Mikelsaar, Ruth; Paves, Heiti (2013). Altered intra-nuclear organization of heterochromatin of chromosome 1 in interphase nuclei of patients with endometriosis by 3D-FISH. Europ J Human Genetics, 21: European Human Genetics Conference 2013, Paris. Nature Publishing Group, 589.
1.1.
2012
Mikelsaar, A.-V.; Sünter, A.; Mikelsaar, R.; Toomik, P.; Kõiveer, A.; Mikelsaar, I.; Juronen, E. (2012). Epitope of titin a-band-specific monoclonal antibody Tit1 5 H1.1 is highly conserved in several Fn3 domains of the titin molecule. Centriole staining in human, mouse and zebrafish cells. Cell Division, 7, Art No 21.10.1186/1747-1028-7-21.
1.1.
2012
Mikelsaar, Ruth; Nelis, M.; Kurg, A.; Zilina, O.; Korrovitš, P.; Rätsep, R.; Väli, M. (2012). Balanced reciprocal translocation t(5;13)(q33;q12) and 9q31.1 microduplication in a man suffering from infertility and pollinosis. Journal of Applied Genetics, 53 (1), 93−97. DOI: 10.1007/s13353-011-0078-5.
5.2.
2012
Mikelsaar, A.-V.; Sünter, A.; Mikelsaar, Ruth; Toomik, P.; Mikelsaar, I.; Juronen, E. (2012). Evolutionary aspects of centriole associated proteins. Europ J Human Genetics: European Human Genetics Conference 2012 in conj. with the European Meeting on Psychosocial Aspects of Genetics, Nürnberg. 251.
5.2.
2012
Mikelsaar, R.; Nelis, M.; Kurg, A.; Žilina, O.; Bartsch, O.; Punab, M.; Korrovitš, P.; Rätsep, R (2012). Genomic imbalances in infertile men detected by array analysis. Europ J Human Genetics: European Human Genetics Conf. 2012 in conjunction with the European Meeting on Psychosocial Aspects of Genetics, Nürnberg. , 119−120.
1.1.
2011
Mikelsaar, R.; Lissitsina, J.; Bartsch, O. (2011). Small supernumerary marker chromosome (sSMC) derived from chromosome 22 in an infertile man with hypogonadotropic hypogonadism. Journal of Applied Genetics, 52, 331−334.10.1007/s13353-011-0041-5.
3.1.
2011
Mikelsaar, Aavo-Valdur; Sünter, Alar; Toomik, Peeter; Mikelsaar, Ruth; Juronen, Erkki (2011). New data on the centrosome proteins. Chromosome Research. The Biology of Chromatin and Chromosomes, 19: 8th European Cytogenetics Conference, Altândega Congress & Exhibition Centre, Portugal, 2-5. july 2011. Springer, S199. (Supplement 1).
5.2.
2011
Mikelsaar, Ruth.; Nelis, M.; Bartsch, O.; Punab, M. (2011). Karyotyping and array analysis in the detection of genomic changes in infertile men. Chromosome Research: 8th European Cytogenetics Conference, Altàndega Congress& Exhibition Centre, Porto(Portugal), 2-5.July 2011. Springer, S89−S90.
1.1.
2010
Mikelsaar, R.; Lissitsina, J.; Ausmees, K.; Punab, M.; Korrovits, P.; Vaidla, E. (2010). Alpha-1 antitrypsin phenotypes in patients with Klinefelter's syndrome. Journal of Genetics, 89 (4), 485−488.
1.1.
2010
Mikelsaar, A-V.; Sünter, A.; Toomik, P.; Mikelsaar, R.; Kalev, I.; Kõiveer, A.; Piirsoo, A.; Karpson, K.; Juronen, E. (2010). Titin A-band-specific Monoclonal Antibody Tit1 5H1.1. Cellular Titin As a Centriolar Protein in Non-muscle Cells. Hybridoma, 29 (5), 391−401. DOI: 10.1089/hyb.2009.0116.
5.2.
2010
Mikelsaar, R.; Lissitsina, J.; Ausmees, K.; Punab, M.; Korrovits, P. (2010). New chromosome aberrations in male hypogonadism. Europ J Human Genetics, 18: European Human Genetics Conference 2010 in conj. with the European Meeting on Psychosocial Aspects of Genetics, Gothenburg. Nature Publishing Group, 116. (1).
5.2.
2010
Lamp, M.; Kaljurand, K.: Mikelsaar, R. (2010). Unusual case of bilateral iridocorneal endothelial syndrome with extraocular anomalies. European J of Human Genetics: European Human Genetics Conference 2010 in conjuction with European Meeting on Psychosocial Aspects of Genetics.Gothenburg,2010. Nature Publishing Group, 80−81.
5.2.
2010
Mikelsaar, A.-V.; Sünter, A.; Toomik, P.; Mikelsaar, R.; Juronen, E. (2010). Titin or a titin-like protein as a human centriolar protein? European Journal of Human Genetics, Supplement 1: European Human Genetics Conference 2010 in conjuction with European Meeting on Psychosocial Aspects of Genetics. Swedish Exhibition & Converence Centre: Nature Publishing Group, 109. (18).
5.1.
2009
Vaidla, E.; Lissitsina, J.; Margus, H.; Ausmees, K.; Punab, M.; Korrovits, P.; Mikelsaar, Ruth. (2009). Association of Klinefelter syndrome with alpha-1 antitrypsin. Chromosome Research, 17(Suppl): Abstract of 7th European Cytogenetics Conference, Stockholm. S63−63.
5.1.
2009
Mikelsaar, R; Margus, H; Korrovits, P. (2009). Chromosomal study in male infertility: survey and a case with unusual reciprocal translocation t(5;13)(q35;q14). Chromosome Research, 17: Abstract of 7th Cytogenetics Conference, Stockholm. S60−60.
5.1.
2009
Mikelsaar, A.-V. ; Sünter, A.; Toomik, P.; Karpson, K. ; Mikelsaar, R.; Juronen, E.. (2009). The subcellular localisation of Ku80 during mitotic cycle - an immunocytochemical analysis using anti Ku80 Mab F10H2.B3. Chromosome Research, 17: 7th European Cytogenetics Conference, Stockholm, 4-7 July 2009. Ed. Herbert Macgregor. Dordrecht, The Netherlands/Norwel,MA,USA: Springer Heidelberg, S172−S172.
5.2.
2009
Mikelsaar, Ruth; Margus, H.; Lissitsina, J.; Korrovitš, P. (2009). Uusi aspekte meeste viljatuse kohta. Eesti Arst. 611. (9).
5.2.
2009
Lissitsina, J.; Mikelsaar, Ruth; Punab, M. (2009). Uus meeste viljatuse kromosomaalne põhjus: lisa inv dup(22)(q11.1). Eesti Arst. 598− . (9).
5.2.
2009
Mikelsaar, A.-V.; Sünter, A.; Toomik, P.; Mikelsaar, R.; Kalev, I.; Vaidla, E.; Kõiver, A.; Piirsoo, A.; Juronen, E. (2009). Tsellulaarne titiin. Uued monoklonaalsed antikehad Tit1 5H1.1 ja Tit2 2E8.1. Eesti Arst. 608−609. (9).
5.2.
2008
Mikelsaar, R.; Molder, H.; Bartsch, O.; Punab, M. (2008). Array CGH analysis (two novel deletions) in pigment dispersion syndrome. European Journal of Human Genetics, 16(2): European Human Genetics Conf. 2008, Barcelona. 160.
1.1.
2007
Mikelsaar, R.; Molder, H.; Bartsch, O.; Punab, M. (2007). Two Novel Deletions (Array CGH Findings) in Pigment Dispersion Syndrome. Ophthalmic Genetics, 28 (4), 216−219.
5.1.
2007
Mikelsaar, Ruth; Lissitsina, J.; Punab, M. (2007). Chromosomes in fertility problems. Chromosome Research, 15: 6th European Cytogenetics Conference, JUL 07-10, 2007. 115.
1.1.
2006
Lissitsina, J.; Mikelsaar, R.; Punab, M. (2006). Cytogenetic analyses in infertile men. Archives of Andrology, 52 (2), 91−95.
1.3.
2006
Lissitsina, J.; Mikelsaar, R.; Punab, M. (2006). Kromosoomianomaaliad ja kromosoomivariandid infertiilsetel meestel. Eesti Arst, 85 (2), 84−89.
5.1.
2006
Mikelsaar, Ruth; Lissitsina, Jelena; Punab, Margus (2006). Cytogenetic analyses of families with fertility problems. European Journal of Human Genetics, 14, 171−171.
5.2.
2006
Lissitsina, J.; Mikelsaar, R.; Punab, M. (2006). Kromosoomihaigused ja varikotseele meeste viljatuse põhjustena. Eesti Arst, 85. 649−650.
5.2.
2006
Mikelsaar, Ruth; Lissitsina, Jelena; Punab, Margus (2006). Cytogenetic study of couples infertile. Laboratorine Medicina, 29 (1), S36.
5.1.
2005
Lissitsina, Jelena; Punab, Margus; Mikelsaar, Ruth (2005). Chromosomal analyses in males with azoo- and oligospermia. Chromosome Research, 13, 71−72.
5.2.
2005
Mikelsaar, R.; Pauklin, M.; Lissitsina, J.; Punab, M. (2005). Infertiilsete meeste tsütogeneetiline uurimine: tulemused ja t(7;16)(q21.2;p13.3) patsiendil oligospermiaga. Eesti Arst, 84 (9), 674−675.
1.3.
2004
Varb, K.; Mikelsaar, Ruth; Lissitsina, J. (2004). Abielupaaride infertiilsuse tsütogeneetilised põhjused. Eesti Arst, 83 (1), 3−8.
5.1.
2004
Mikelsaar, Ruth; Roomets, Eva; Pihlau, Helju (2004). New syndrome - chromosome 19q distal deletion syndrome. European Journal of Human Genetics, 12, 136.
5.2.
2004
Mikelsaar, R.; Roomets, E.; Pihlau, E. (2004). Uus kromosoomihaigus - 19q distaalne deletsioon. Eesti Arst, 83. 619.
5.1.
2003
Mikelsaar, Ruth; Vessel, Epp; Mölder, Hillar; Punab, Margus (2003). Translocation t(10;15) in a man with pigment dispersion syndrome and infertility. European Journal of Human Genetics, 11, 303.
5.2.
2003
Lissitsina, J.; Mikelsaar, R.; Varb, K.; Punab, M. (2003). Infertiilsete meeste tsütogeneetiline uurimine. Eesti Arst, 82. , 637.
5.2.
2003
Lissitsina, J.; Mikelsaar, Ruth; Varb, K.; Punab, M. (2003). Cytogenetic study in infertile men. Annales De Génétique. 185.
1.1.
2002
Mikelsaar, RV.; Muru, K.; Kulla, A.; Suvari, A. (2002). Psoriasis vulgaris in a male with partial deletion 18p. American Journal of Medical Genetics, 108 (3), 252−253.
5.1.
2002
Lissitsina, J.; Mikelsaar, R.; Varb, K.; Punab, M. (2002). Chromosomal analyses in infertile men. European Journal of Human Genetics, 10, 160−160.
5.1.
2002
Mikelsaar, Ruth; Muru, Kai; Varb, Kadi; Kulla, Andres; Süvari, Anneli (2002). Deletion 18p in a Patient with Psoriasis Vulgaris. European Journal of Human Genetics, 10, 151.
5.2.
2002
Varb, K.; Mikelsaar, R.; Lissitsina, J.; Punab, M. (2002). Lastetute abielupaaaride tsütogeneetiline uurimine. Eesti Arst, 81 (9), 593.
1.2.
2001
Mikelsaar, R.; Varb, K.; Suvari, A.; Schinzel, A. (2001). Mosaic terminal del(19)(q13.33:) in a girl with seizures and mental retardation. Journal of Medical Genetics, 38 (1), e2−e5. DOI: 10.1136/jmg.38.1.e2.
2.2.
2001
Mikelsaar, Ruth (2001). Kromosoomihaigused. Tartu: Atlex.
5.1.
2001
Mikelsaar, Ruth; Salo, Armi; Varb, Kadi; Süvari, Anneli; Muru, Kai; Teek, Rita. (2001). Chromosome analysis in mental retardation. European Journal of Human Genetics, 9, 145.
5.2.
2001
Lissitsina, Jelena; Mikelsaar, Ruth; Varb, Kadi; Timberg, Gennadi; Punab, Margus (2001). Two cases of extra marker chromosome in infertile men. European Journal of Human Genetics, 9, 148.
5.1.
2000
Mikelsaar, R.; Varb, K.; Lissitsina, J.; Mikelsaar, A.-V. (2000). Extra marker chromosome in an infertile man. European Journal of Human Genetics, 8. 92.
1.1.
1999
Mikelsaar, RV.; Viikmaa, M. (1999). Neonatal thyroid-stimulating hormone screening as an indirect method for the assessment of iodine deficiency in Estonia. Hormone Research, 52 (6), 284−286.
5.1.
1999
Toublanc, J.-E.; Ratajczak, R.; Stoeva, I.; Tsukerman, G.; Mikelsaar, R. (1999). Epidemiology of Congenital Hypothyroidism, Its Relation with Iodine Deficiency in Eastern Europe. Hormone Research, 51(2): 38th Annual Meeting of the European Society for Paediatric Endocrinology (ESPE); Warsaw, Poland; 29 August - 1 September, 1999. _EditorsAbbr Romer, T. 3.
5.2.
1999
Mikelsaar, R.; Varb, K.; Süvari, A. (1999). Mosaic deletion del(19)(q13.33qter) in a girl with epilepsy and mental retardation. European Journal of Human Genetics, 7(1). 76.
1.1.
1998
Mikelsaar, RV.; Zordania, R.; Viikmaa, M.; Kudrjavtseva, G. (1998). Neonatal screening for congenital hypothyroidism in Estonia. Journal of Medical Screening, 5 (1), 20−21.
1.3.
1998
Mikelsaar, Ruth; Kudrjavtseva, G.; Viikmaa, M. (1998). Kaasasündinud hüpotüreoosi sõeluuring Eestis. Eesti Arst, 77 (3), 195−198.
5.1.
1998
Mikelsaar, AV.; Beckman, L.; Tasa, G.; Parlist, P.; Mikelsaar, R. (1998). The frequency of hemochromatosis mutation C282Y in Estonian population. European Journal of Human Genetics, 6, 106−106.
1.1.
1996
Mikelsaar, RV.; Lurie, IW.; Ilus, TE. (1996). 'Pure'' partial trisomy 4q25-qter owing to a de novo 4;22 translocation. Journal of Medical Genetics, 33 (4), 344−345.
1.1.
1994
Robinson, W.; Binkert, F.; Schinzel, A.; Basaran, S.; Mikelsaar, R. (1994). Multiple origins of x-chromosome tetrasomy. Journal of Medical Genetics, 31 (5), 424−425.
1.3.
1993
Mikelsaar, Ruth (1993). Laste geneetiline uurimine Eestis. Eesti Arst, 72 (1), 4−6.
2.3.
1993
Mikelsaar, Ruth (1993). Etiological Factors of Diseases in Genetically Consulted Children and Newborn Screening. (Doktoritöö, Tartu Ülikool, Arstiteaduskond). Tartu: Tartu University Press.
1.1.
1992
Mikelsaar, RVA.; Lurie, IW. (1992). Atypical case of aarskog syndrome. Journal of Medical Genetics, 29 (5), 349−350.
1.2.
1992
Mikelsaar, R.; Mikelsaar, A.-V.; Kudrjavtseva, G. (1992). Newborn Screening for Congenital Hypothyroidism in Estonia. Infant Screening, 15 (4), 17−18.
1.3.
1991
Mikelsaar, R. (1991). The Allunion conference - Prenatal and Neonatal Screening for Congenital and Genetic Pathology - in Kharkow 22-23.11.1990. Eesti Arst, 140−141.
3.2.
1991
Mikelsaar, R. (1991). Neonatal Screening for Congenital Hypothyroidism. Genetics and Prophylaxis of Inherited diseases (101−103).. Vilnius: Mokslas.
1.3.
1990
Mikelsaar, Ruth (1990). Kaasasündinud hüpotüreoosi varane diagnoosimine. Eesti Arst, 5, 339−342.
1.3.
1988
Ilus, T.; Mikelsaar, R. (1988). Edwardsi sündroom e. 18. kromosoomi trisoomia. Nõukogude Eesti Tervishoid, 4, 245−148.
3.2.
1988
Mikelsaar, R.; Vasar, M. (1988). Rubinstein-Taybi Syndrome. In: Proceedings of the University of Tartu "Trudõ po meditsine" (143−148).. Tartu: Tartu Ülikooli Kirjastus.
1.1.
1987
Mikelsaar, RV.; Ilus, TA.; Lurie, IW. (1987). Distal trisomy 14q. Journal of Medical Genetics, 24 (6), 380−381.
3.5.
1987
Mikelsaar, R. (1987). Medico-genetic counseling of patients with mental and psychomotor retardation in Children Hospital. Genetic studies in Soviet Estonia (66−69).. Tallinn: Eesti NSV Teaduste Akadeemia.
2.3.
1980
Mikelsaar, RV-A. (1980). Dermatoglyphics in patients with schizophrenia, neurosis and oligophrenia (Cand.dissert). (Doktoritöö, Tartu Ülikool, Arstiteaduskond). Tartu: Tartu University Press.
3.2.
1977
Mikelsaar, R. (1977). Dermatoglyphics of fingers and palms in neurotics. Trudõ po meditsine XXXIV (110−120).. Tartu: Tartu State University.
1.1.
1976
Kaosaar, ME.; Mikelsaar, AVN.; Talvik, TA.; Mikelsaar, RVA. (1976). Case of trisomy for short arm of chromosome no9 (+9(p)). Human Genetics, 34 (1), 77−80.
1.1.
1974
Horn, AV.; Mikelsaar, RVA. (1974). Dermal patterns in normal Estonians. Human Heredity, 24, 488−495.
1.1.
1973
Mikelsaar, AV.; Lazjuk, GJ.; Lurie, JW.; Tuur, S.; Kaosaar, ME.; Mikelsaar, R.; Loolaid, VE. (1973). A 4p-syndrome. A case report. Humangenetik, 19 (3), 345−347.
1.1.
1973
Talvik, T.; Mikelsaar, AV.; Mikelsaar, R.; Kaosaar, M.; Tuur, S. (1973). Inherited translocations in 2 families (t(14q+ - 10q-) and t(13q- - 21q+)). Humangenetik, 19, 215−226.
1.1.
1972
Talvik, TA.; Mikelsaar, RV.; Mikelsaar, AN. (1972). Family reciprocal translocation between c-group chromosome and d-group chromosome[46, t(cq- - dq+)]. Genetika, 8 (5), 123.
1.3.
1972
Mikelsaar, R. (1972). Dematoglüüfide uurimise tähtsus meditsiinilises geneetikas. Nõukogude Eesti Tervishoid, 3, 198−201.
1.1.
1971
Talvik, TA.; Mikelsaar, A-VN.; Mikelsaar, RV-A.; Kask, VA. (1971). A Ring Heterosoma (46,XXr or 46,XYr) in a 2,5 Year Old Girl. Genetika (Moskva), 7, 136−142.
1.1.
1971
Mikelsaar, A-V.N; Naidionova, MM.; Talvik, T.A.; Mikelsaar, Ruth V.-A. Kaselaid VL; Zucker, EI; Grinberg, KN. (1971). XX/X0 Mosaicism in a new-born female infant with an atypical phenotype. Genetika (Moskva), 2, 152−160.
1.1.
1971
Mikelsaar, RV-A. (1971). Characteristic Features of Dermatoglyphics in Cases of Schizophrenia. Genetika (Moskva), 3, 139−146.
1.1.
1971
Mikelsaar, A-VN.; Blumina, MG.; Kuznetsova, LI.; Mikelsaar, RV-A.; Lurie, IV. (1971). A Double Chromosome Aberration 47,XX,21+/47,XXp-q-,21+ in a Girl with Symptoms of Down's and Turner's Syndromes. Genetika (Moskva), 5, 156−161.
1.1.
1971
Mikelsaar, A-VN.; Blumina, MG.; Kuznetsova, LI.; Mikelsaar, RV. (1971). Children with an XYY sex chromosome set. Genetika (Moskva), 8, 156−165.
3.2.
1971
Mikelsaar, R. (1971). Peculiarities of Dermatoglyphics in Schizophrenia. Problems of Medical Genetics and Human Genetics (141−143).. Minsk: Nauka i Tehnika.
3.2.
1968
Mikelsaar, R.;Tamm, EN. (1968). Combination of Klinefelter's syndrome and Schizophrenia. Proceedings of the University of Tartu "Research in medicine" (75−79).. TÜ Kirjastus.
6.09.2021

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