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Olen nõus

Tõnis Kanger

https://www.etis.ee/CV/Tõnis_Kanger/est
6.05.1959
6204371
tonis.kanger@ttu.ee
H-2462-2015

Teenistuskäik

Töökohad ja ametid
01.01.2017–...   
Tallinna Tehnikaülikool, Loodusteaduskond, Keemia ja biotehnoloogia instituut, Professor (1,00)
01.01.2017–...   
Tallinna Tehnikaülikool, Loodusteaduskond, dekaan (1,00)
1998- TTÜ keemiainstituut, dotsent
1990-1998 Keemia Instituut, Tallinn, vanemteadur
1993 P.M.Curie Ülikool, Pariis, järeldoktorant,
1982-1990 Keemia Instituut, Tallinn, nooremteadur
1988 Orgaanilise Keemia Instituut, Warssavi,stazöör,
01.09.2010–31.12.2016   
Tallinna Tehnikaülikool, Matemaatika-loodusteaduskond, dekaan (1,00)
2006–31.12.2016   
Tallinna Tehnikaülikool, Matemaatika-loodusteaduskond, Keemiainstituut, Orgaanilise keemia õppetool, Professor (1,00)
2005–2006   
Tallinna Tehnikaülikool, Matemaatika-loodusteaduskond, Keemiainstituut, Orgaanilise keemia õppetool, Dotsent (1,00)
 
 
Haridustee
1982 Tartu Riiklik Ülikool, orgaaniline keemia
1977 Tallinna 2. Keskkool
 
 
Teadusorganisatsiooniline ja -administratiivne tegevus
2016−...   
riigi teaduspreemiate komisjoni liige
2013−...   
Riikliku programmi „Eestikeelsed kõrgkooliõpikud 2013-2017“ keemia- ja molekulaarbioloogia valdkonna ekspertkomisjoni esimees
2012−...   
Konverentsi "Balticum Organicum Syntheticum (BOS)" organiseerimiskomitee liige
2010−...   
TTÜ matemaatika-loodusteaduskonna dekaan
2010−...   
TTÜ nõokogu liige
2010−...   
TTÜ valituse liige
2008−...   
TTÜ matemaatika-loodusteaduskonna nõukogu liige
Eesti Keemia Seltsi liige
2013−2016   
TTÜ Küberneetika Instituudi nõukogu liige
2013−2015   
Prantsuse Teadusagentuuri (ANR) ekspert
2010−2014   
Eesti esindaja valdkondlikus COST komitees (CM0905)
2008−2010   
ETF ekspertkomisjoni liige
2008−2012   
TTÜ keemiainstituudi nõukogu liige
 
 
Loometöö
Kõrgkooliõpiku "Orgaaniline keemia" (F. C . Carey, R. M. Giuliano, TTÜ kirjastus, Tallinn 2014) toimetaja.
 
 
Teenistuskäigu lisainfo
Õppetöö läbiviimine TTÜ-s: YKO0070 Orgaaniline keemia I (harjutustunnid), YKO5606 Orgaaniline keemia II , YKO0100 Orgaanilise sünteesi meetodid, YKO5313 Orgaaniline süntees - ainetöö;

Kvalifikatsioon

Teaduskraadid
Tõnis Kanger, doktorikraad, 1990, (juh) Margus Lopp; Ülo Lille, Bitsüklilised oksiraanid ja liitium/BF3 reagent prostaglandiinide enantiomeersete vaheühendite sünteesil, Eesti Teaduste Akadeemia.
 
 
Teaduspreemiad ja tunnustused
2016, Tõnis Kanger, EV teaduspreemia keemia ja molekulaarbioloogia ala
2004, Tõnis Kanger, EV teaduspreemia
 
 
Teadustöö põhisuunad
VALDKOND: 4. Loodusteadused ja tehnika; 4.11. Keemia ja keemiatehnika; CERCS ERIALA: P390 Orgaaniline keemia
 
 
Lisainfo
keemiakandidaat
ENSV TA Keemia Instituut, 1990

Jooksvad projektid

Lõppenud projektid

Juhendamisel väitekirjad

Juhendatud väitekirjad

Publikatsioonid

Klass
Aasta
Publikatsioon
 
1.1.
2018
Trubitsõn, D.; Žari, S.; Kaabel, S.; Kudrjashova, M.; Kriis, K.; Järving, I.; Pehk, T.; Kanger, T. (2018). Asymmetric Organocatalytic Cascade Synthesis of Tetrahydro­furanyl Spirooxindoles. Synthesis, 50 (02), 314−322.10.1055/s-0036-1590918.
5.2.
2018
Murre, A.; Erkman, K.; Kanger, T. (2018). Diastereoselective Stevens [2,3]-Rearrangement of N-Allyl Ammonium Ylides. Balticum Organicum Syntheticum, July 1-4, 2108, Tallinn, Estonia. , 110.
1.1.
2017
Kriis, K.; Melnik, T.; Lips, K.; Juhanson, I.; Kaabel, S.; Järving, I.; Kanger, T. (2017). Asymmetric Synthesis of 2,3,4-Trisubstituted Piperidines. Synthesis, 49 (3), 604−614.10.1055/s-0036-1588299.
1.1.
2017
Ošeka, M.; Kimm, M.; Järving, I.; Lippur, K.; Kanger, T. (2017). Two Catalytic Methods of an Asymmetric Wittig [2,3]-Rearrangement. Journal of Organic Chemistry, 82 (6), 2889−2897.10.1021/acs.joc.6b02786.
1.1.
2017
Kaasik, M.; Kaabel, S.; Kriis, K.; Järving, I.; Aav, R.; Rissanen, K.; Kanger, T. (2017). Synthesis and Characterisation of Chiral Triazole-Based Halogen-Bond Donors: Halogen Bonds in the Solid State and in Solution. Chemistry - A European Journal, 23 (30), 7337−7344.10.1002/chem.201700618.
1.1.
2017
Metsala, A.; Žari, S.; Kanger, T. (2017). Reaction path scans: Aza-Michael reactions of isatin Imines. Computational and Theoretical Chemistry, 1117, 30−40.10.1016/j.comptc.2017.07.014.
1.1.
2017
Ben Moussa, S.; Lachheb, J.; Gruselle, M.; Maaten, B.; Kriis, K.; Kanger, T.; Tõnsuaadu, K.; Badraoui, B. (2017). Calcium, Barium and Strontium apatites: A new generation of catalysts in the Biginelli reaction. Tetrahedron, 73 (46), 6542−6548.10.1016/j.tet.2017.09.051.
5.2.
2017
Siim, E.; Gathergood, N.; Kanger, T. (2017). Catalysts derived from sustainable natural and value added alkaloids from poppies. In: .FMTDK Teaduskonverents, Tartu 07.03.2017-08.03.2017.
1.1.
2016
Ošeka, M.; Kimm, M.; Kaabel, S.; Järving, I.; Rissanen, K.; Kanger, T. (2016). Asymmetric Organocatalytic Wittig [2,3]-Rearrangement of Oxindoles. Organic Letters, 18 (6), 1358−1361.10.1021/acs.orglett.6b00291.
1.1.
2016
Metsala, A.; Žari, S.; Kanger, T. (2016). Aza-Michael Reactions of Isatin Imines: Deeper Insight and Origin of the Stereoselectivity. ChemCatChem, 8 (18), 2961−2967.10.1002/cctc.201600584.
5.2.
2016
Lippur, K.; Kanger, T. (2016). Asymmetric Ca-Catalyzed Wittig [2,3]-Rearrangement of Allyloxy 1,3-Dicarbonyl Compounds. Balticum Organicum Syntheticum, Riga, Latvia, July 3-6, 2016. -, 106.
5.2.
2016
Trubitsõn, D.; Žari, S.; Kudrjashova, M.; Lippur, K.; Ošeka, M.; Kanger, T. (2016). Enantioselective Organocatalytic Synthesis of Oxa-Spirooxindole Derivatives. Balticum Organicum Syntheticum, Riga, Latvia, July 3-6, 2016. -, 161.
1.1.
2015
Lippur, K.; Kaabel, S.; Järving, I.; Rissanen, K.; Kanger, T. (2015). CaCl2, Bisoxazoline, and Malonate: A Protocol for an Asymmetric Michael Reaction. Journal of Organic Chemistry, 80 (12), 6336−6341.10.1021/acs.joc.5b00769.
1.1.
2015
Kaasik, M.; Noole, A.; Reitel, K.; Järving, I.; Kanger, T. (2015). Organocatalytic Conjugate Addition of Cyclopropylacetaldehyde Derivatives to Nitro Olefins: en Route to β- and γ-Amino Acids. European Journal of Organic Chemistry, 8, 1745−1753.10.1002/ejoc.201403387.
1.1.
2015
Žari, S.; Metsala, A.; Kudrjashova, M.; Kaabel, S.; Järving, I.; Kanger, T. (2015). Asymmetric Organocatalytic Aza-Michael Reactions of Isatin Derivatives. Synthesis, 47 (6), 875−886.10.1055/s-0034-1379956.
1.1.
2015
Preegel, Gert; Ilmarinen, Kaja; Järving, Ivar; Kanger, Tõnis; Pehk, Tõnis; Lopp, Margus (2015). Enantioselective Organocatalytic Michael Addition-Cyclization Cascade of Cyclopentane-1,2-dione with Substituted (E)-2-oxobut-3-enoates. Synthesis, 3805−3812.
1.1.
2015
Paju, A.; Kostromarova, D.; Matkevitš, K.; Laos, M.; Pehk, T.; Kanger, T.; Lopp, M. (2015). 3-Alkyl-1,2-cyclopentanediones by Negishi cross-coupling of a 3-bromo-1,2-cyclopentanedione silyl enol ether with alkylzinc reagents: an approach to 2-substituted carboxylic acid gamma-lactones, homocitric and lycoperdic acids. Tetrahedron, 71 (49), 9313−9320.10.1016/j.tet.2015.10.014.
1.1.
2014
Paju, A.; Kanger, T.; Müürisepp, A-M.; Aid, T.; Pehk, T.; Lopp, M. (2014). Sonogashira cross-coupling of 3-bromo-1,2-diones: an access to 3-alkynyl-1,2-diones. Tetrahedron, 70 (35), 5843−5848.10.1016/j.tet.2014.06.037.
1.1.
2014
Preegel, G.; Noole, A.; Ilmarinen, K.; Järving, I.; Kanger, T.; Pehk, T.; Lopp, M. (2014). Enantioselective Organocatalytic Michael Addition of Cyclopentane-1,2-diones to Nitroolefins. Synthesis, 46 (19), 2595−2600.10.1055/s-0034-1378374.
1.1.
2014
Kreek, K.; Kriis, K.; Maaten, B.; Uibu, M.; Mere, A.; Kanger, T.; Koel, M. (2014). Organic and carbon aerogels containing rare-earth metals: Their properties and application as catalysts. Journal of Non-Crystalline Solids, 404, 43−48.10.1016/j.jnoncrysol.2014.07.021.
1.1.
2014
Maaten, B.; Moussa, J.; Desmarets, C.; Gredin, P.; Beaunier, P.; Kanger, T.; Tõnsuaadu, K.; Villemin, D.; Gruselle, M. (2014). Cu-Modified Hydroxy-Apatite as Catalyst for Glaser-Hay C-C Homo- Coupling Reaction of Terminal Alkynes. Journal of Molecular Catalysis A: Chemical, 393, 112−116.doi:10.1016/j.molcata.2014.06.011.
1.1.
2014
Ošeka, M.; Noole, A.; Žari, S.; Öeren, M.; Lopp, M.; Kanger, T. (2014). Asymmetric Diastereoselective Synthesis of Spirocyclopropane Derivatives of Oxindole. European Journal of Organic Chemistry, 2014 (17), 3599−3606.
1.1.
2014
Žari, S.; Kudrjashova, M.; Pehk, T.; Lopp, M.; Kanger, T. (2014). Remote Activation of the Nucleophilicity of Isatin. Organic Letters, 16 (6), 1740−1743.10.1021/ol500421k.
5.2.
2014
Kudrjashova, M.; Žari, S.; Pehk, T.; Kanger, T. (2014). NMR study of the remote activation of the nucleophilicity of isatin imines. 8th Biennal International Conference on Organic Synthesis - Balticum Organicum Syntheticum (BOS2014). July 6-9, 2014, Vilnius. 87.
5.2.
2014
Preegel, G.; Noole, A.; Kanger, T.; Pehk, T.; Lopp, M. (2014). Enantioselective organocatalytic Michael addition of cyclopentane-1,2-diones to electrophiles. Balticum Organicum Syntheticum, Vilnius, Lithuania, July 6-9.
5.2.
2014
Kriis, K.; Ausmees, K.; Plado, A.; Pehk, T.; Lopp, M.; Kanger, T. (2014). Diastereoselective multicomponent cascade reaction for the synthesis of heterobicyclic heptanes. Program and Abstract Book of 8th Biennial International Conference on Organic Synthesis: Balticum Organicum Syntheticum, Vilnius, July 6-9, 2014.
5.2.
2014
Noole, A.; Kanger, T.. (2014). Asymmetric synthesis of congested spiro-cyclopentaneoxindoles via an organocatalytic cascade reaction. 248th ACS National Meeting & Exposition, USA, San Fransisco, CA, 2014. American Chemical Society,.
5.2.
2014
Noole, A.; Ošeka, M.; Malkov, A.; Lopp, M.; Kanger, T. (2014). Asymmetric organocatalytic synthesis of spiro-cyclopropyloxindoles. Balticum Organicum Syntheticum: International Conference on Organic Synthesis 2014, Lithuania, Vilnius, July 6-9, 2014.
5.2.
2014
Lippur, K.; Lopp, M.; Kanger, T. (2014). Calcium-catalyzed asymmetric reactions of 1,3-dicarbonyl compounds. 8th Biennial International Conference on Organic Synthesis, Balticum Organicum Syntheticum, July 6-9, 2014, Vilnius. -, 94.
1.1.
2013
Reitel, K.; Lippur, K.; Järving, I.; Kudrjašova, M.; Lopp, M.; Kanger, T. (2013). Asymmetric Aminocatalytic Michael Addition of Cyclopropane-Containing Aldehydes to Nitroalkenes. Synthesis, 45 (19), 2679−2683.10.1055/s-0033-1338704.
1.1.
2013
Noole, A.; Malkov, A. V.; Kanger, T.. (2013). Asymmetric Organocatalytic Synthesis of Spiro-cyclopropaneoxindoles. Synthesis, 45 (18), 2520−2524.
1.1.
2013
Noole, A.; Ilmarinen, K.; Järving, I.; Lopp, M.; Kanger, T. (2013). Asymmetric Synthesis of Congested Spiro-cyclopentaneoxindoles via an Organocatalytic Cascade Reaction. Journal of Organic Chemistry, 78 (16), 8117−8122.10.1021/jo4008223.
1.1.
2013
Noole, Artur; Ošeka, Maksim; Pehk, Tõnis; Öeren, Mario; Järving, Ivar; Elsegood, Mark; Malkov, Andrei; Lopp, Margus; Kanger, Tõnis. (2013). 3-Chlorooxindoles: Versatile Starting Materials for Asymmetric Organocatalytic Synthesis of Spirooxindoles. Advanced Synthesis and Catalysis, 355 (5), 829−835.
5.2.
2013
Preegel, G.; Noole, A.; Kanger, T.; Lopp, M. (2013). Enantioselective organocatalytic Michael addition of cyclopentane-1,2-diones to nitro olefins. ESOC 2013, Marseille, France, July 7-12.
5.2.
2013
Reitel, K.; Lippur, K.; Järving, I.; Kudrjašova, M.; Lopp, M.; Kanger, T. (2013). Aminocatalytic Michael addition of cyclopropane-containing aldehydes to nitroolefines. ESOC Marseille, France July 7-12.
5.2.
2013
Tõnsuaadu, K.; Gruselle, M.; Moussa, J.; Villemin, D.; Maaten, B.; Kanger, T. (2013). Modified calcium apatites as new catalysts in organic synthesis. International Symposium on Inorganic and Environmental Materials 2013, Programm and abstracts, October 27-31, 2013, Rennes, France. 277.
1.1.
2012
Noole, A.; Järving, I.; Werner, F.; Lopp, M.; Malkov, A.; Kanger, T. (2012).

Organocatalytic Asymmetric Synthesis of 3-Chlorooxindoles Bearing Adjacent Quaternary–Tertiary Centers

. Organic Letters, 14 (18), 4922−4925.10.1021/ol302245b.
1.1.
2012
Lippur, K.; Tiirik, T.; Kudrjashova, M.; Järving, I.; Lopp, M.; Kanger, T. (2012). Amination of quinolones with morpholine derivatives. Tetrahedron, 68 (47), 9550−9555.10.1016/j.tet.2012.09.082.
1.1.
2012
Žari, S.; Kailas, T.; Kudrjashova, M.; Öeren, M.; Järving, I.; Tamm, T.; Lopp, M.; Kanger, T. (2012). Organocatalytic asymmetric addition of malonates to unsaturated 1,4-diketones. Beilstein Journal of Organic Chemistry, 8, 1452−1457.
1.1.
2012
Reinart-Okugbeni, Reet; Ausmees, Kerti; Kriis, Kadri; Rinken, Ago; Kanger, Tõnis (2012). Chemoenzymatic synthesis and evaluation of 3-azabicyclo[3.2.0]heptane derivatives as dopaminergic ligands. European Journal of Medicinal Chemistry, 55, 255−261.10.1016/j.ejmech.2012.07.025.
1.1.
2012
Reile, I.; Paju, A.; Kanger, T.; Järving, I.; Lopp, M. (2012). Cyclopentane-1,2-dione bis(tert-butyldimethylsilyl) enol ether in asymmetric organocatalytic Mukaiyama–Michael reactions. Tetrahedron Letters, 53 (12), 1476−1478.10.1016/j.tetlet.2012.01.041.
1.1.
2012
Noole, A.; Pehk, T.; Järving, I.; Lopp, M.; Kanger, T. (2012). Organocatalytic asymmetric synthesis of trisubstituted pyrrolidines via a cascade reaction. Tetrahedron-Asymmetry, 23 (2), 188−198.10.1016/j.tetasy.2012.01.021.
1.1.
2012
Ausmees, K.; Kriis, K.; Pehk, T.; Werner, F.; Järving, I.; Lopp, M.; Kanger, T. (2012). Diastereoselective Multicomponent Cascade Reaction Leading to [3.2.0]-Heterobicyclic Compounds. Journal of Organic Chemistry, 77 (23), 10680−10687.10.1021/jo3019413.
1.1.
2012
Noole, A.; Suckman, N.; Kabeshov, M.; Kanger, T.; Macaev, F.; Malkov, A. (2012). Highly Enantio- and Diastereoselective Generation of Two Quaternary Centers in Spirocyclopropanation of Oxindole Derivatives. Chemistry - A European Journal, 18 (47), 14929−14933.10.1002/chem.201203099.
5.2.
2012
Gruselle, M.; Kanger, T.; Flambard, A.; Kriis, K.; Mikli, V.; Maaten, B.; Tonsuaadu, K. (2012). Calcium fluor- and hydroxy-apatites modified or not as catalysts for C-C bond formation. Book of Abstracts: Catalysis in Organic Synthesis: Catalysis in Organic Synthesis, September 15-20, 2012, Moscow, Russia. Moscow, Russia, 190.
5.2.
2012
Lippur, K.; Tiirik, T.; Kudrjašova, M.; Lopp, M.; Kanger, T. (2012). Amination of Quinolones. Balticum Organicum Syntheticum 2012 : abstracts: The 7th Biannual international conference on organic synthesis, Tallinn, Estonia. 1-4th of July 2012.
5.2.
2012
Kriis, K.; Ausmees, K.; Pehk, T.; Lopp, M.; Kanger, T. (2012). Diastereoselective multicomponent cascade reaction leading to heterobicyclic heptanes. 13th Florida Heterocyclic and Synthetic Conference: FloHet-2012, Florida, March 4-6, 2012.
5.2.
2012
Reitel, K.; Kudrjašova, M.; Lopp, M.; Kanger, T. (2012). Cyclopropane-containing compounds in organocatalytic Michael reaction. Balticum Organicum Syntheticum 2012, Tallinn, 1-4 July 2012. , 2012..
1.1.
2011
Ausmees, K.; Selyutina, A.; Kütt, K.; Lippur, K.; Pehk, T.; Lopp, M.; Žusinaite, E.; Merits, A.; Kanger, T. (2011). Synthesis and biological activity of bimorpholine and its carbanucleoside. Nucleosides Nucleotides & Nucleic Acids, 30 (11), 897−907.10.1080/15257770.2011.621919.
1.1.
2011
Gruselle, M.; Kanger, T.; Thouvenot, R.; Flambard, A.; Kriis, K.; Mikli, V.; Traksmaa, R.; Maaten, B.; Tõnsuaadu, K. (2011). Calcium Hydroxyapatites as Efficient Catalysts for the Michael CC Bond Formation. ACS Catalysis, 1729−1733.10.1021/cs200460k.
1.1.
2011
Laars, M.; Ausmees, K.; Kudrjashova, M.; Kanger, T.; Werner, F. (2011). rac -2,2’-Bipiperidine-1,1’-diium dibromide. Acta Crystallographica Section E: Structure Reports Online, 67 (6), o1324.10.1107/S1600536811016084.
1.1.
2011
Noole, A.; Borissova, M.; Lopp, M.; Kanger, T. (2011). Enantioselective Organocatalytic Aza-Ene-Type Domino Reaction Leading to 1,4-Dihydropyridines. Journal of Organic Chemistry, 76 (6), 1538−1545.10.1021/jo200095e.
1.1.
2010
Laars, M.; Raska, H.; Lopp, M.; Kanger, T. (2010). Cyclic amino acid salts as catalysts for the asymmetric Michael reaction. Tetrahedron-Asymmetry, 21 (5), 562−565.10.1016/j.tetasy.2010.02.025.
1.1.
2010
Kriis, K.; Ausmees, K.; Pehk, T.; Lopp, M.; Kanger, T. (2010). A Novel Diastereoselective Multicomponent Cacade Reaction. Organic Letters, 12 (10), 2230−2233.10.1021/ol1005714.
1.1.
2010
Noole, A.; Lippur, K.; Metsala, A.; Lopp, M.; Kanger, T.. (2010). Enantioselective Henry Reaction Catalyzed by CuII Salt and Bipiperidine. Journal of Organic Chemistry, 75 (4), 1313−1316.10.1021/jo902664v.
1.1.
2010
Uudsemaa, M.; Kanger, T.; Lopp, M.; Tamm, T. (2010). pKa calculation for monoprotonated bipiperidine, bimorpholine and their derivatives in H2O and MeCN. Chemical Physics Letters, 485, 83−86.10.1016/j.cplett.2009.12.006.
1.1.
2010
Lippur, K.; Elmers, C.; Kailas, T.; Müürisepp, A-M.; Pehk, T.; Kanger, T.; Lopp, M. (2010). Synthesis of 5,5'-disubstituted bimorpholines. Synthetic Communications, 40 (2), 266−281.10.1080/00397910902964874.
5.2.
2010
Lippur, K.; Merits, A.; Lopp, M.; Kanger, T. (2010). Synthesis of 2,2’-bimorpholines and their biological activity. Balticum Organicum Syntheticum 2010, Riga, 27-30 June 2010.
5.2.
2010
Kriis, K.; Ausmees, K.; Pehk, T.; Lopp, M.; Kanger, T. (2010). A novel diastereoselective multicomponent cascade reaction. Program and Abstracts BOS 2010 International Conference on Organic Synthesis: BOS 2010 International Conference on Organic Synthesis, Riga - Latvia, June 27 - 30, 2010. 117.
5.2.
2010
Reitel, K.; Lopp, M.; Kanger, T. (2010). Synthesis of ILS (S,S')-bipiperidine derivatives and their application as organocatalysts. Balticum Organicum Syntheticum 2010, Riga, 27-30 June 2010. , 2010..
6.2.
2010
Kanger, T. (2010). Orgaanilise keemia nomenklatuuri põhimõtted. Tallinna Tehnikaülikooli Kirjastus.
1.1.
2009
Laars, M.; Ausmees, K.; Uudsemaa, M.; Tamm, T.; Kanger, T.; Lopp, M. (2009). Enantioselective Organocatalytic Michael Addition of Aldehydes to β-Nitrostyrenes. Journal of Organic Chemistry, 74 (10), 3772−3775.10.1021/jo900322h.
1.1.
2009
Uudsemaa, M.; Laars, M.; Kriis, K.; Tamm, T.; Lopp, M.; Kanger, T. (2009). Influence of protonation upon the conformations of bipiperidine, bimorpholine, and their derivatives. Chemical Physics Letters, 417, 92−96.10.1016/j.cplett.2009.02.027.
5.2.
2009
Noole, A.; Kanger, T. (2009). Synthesis of 2-(2'-piperidinyl)pyridine derivatives and their use as ligands in asymmetric Henry and aza-Henry reactions. 16th European Symposium on Organic Chemistry (ESOC 2009), Praha, 12-16 juuli. 422.
6.2.
2009
Kanger, T.; Laasik, M. (2009). Orgaanilise keemia praktikum. Laboratoorsed tööd I. Tallinna Tehnikaülikooli Kirjastus.
1.1.
2008
Laars, M.; Kriis, K.; Kailas, T.; Müürisepp, A.M.; Pehk, T.; Kanger, T.; Lopp, M. (2008). Structural constraints for C-2-symmetric heterocyclic organocatalysts in asymmetric aldol reactions. Tetrahedron-Asymmetry, 19 (6), 641−645.
5.2.
2008
Aav, R.; Kanger, T.; Lopp, M. (2008). Synthesis of 9,11-secosterol D-ring synthon. International Conference on Organic Synthesis-BOS2008, Vilnius 2008: Balticum Organicum Syntheticum 2008, Vilnius.
1.1.
2007
Sulzer-Mossé, S.; Laars, M.; Kriis, K.; Kanger, T.; Alexakis, A. (2007). Synthesis and Use of 3,3’-Bimorpholine Derivatives in Asymmetric Michael Addition and Intramolecular Aldol Reaction. Synthesis, 11, 1729−1732.
1.1.
2007
Kanger, T.; Kriis, K.; Laars, M.; Kailas, T.; Müürisepp, A-M.; Pehk, T.; Lopp, M. (2007). Bimorpholine-Mediated Enantioselective Intramolecular and Intermolecular Aldol Condensation. Journal of Organic Chemistry, 72, 5168−5173.
1.1.
2007
Kriis, K.; Laars, M.; Lippur, K.; Kanger, T. (2007). Bimorpholines as Alternative Organocatalysts in Asymmetric Aldol Reaction. Chimia, 61 (5), 232−235.
1.1.
2007
Lippur, K.; Kanger, T.; Kriis, K.; Kailas, T.; Müürisepp, A-M.; Pehk, T.; Lopp, M. (2007). Synthesis of (2S,2’S)-bimorpholine N,N’-quaternary salts as chiral phase transfer catalysts. Tetrahedron-Asymmetry, 18 (1), 137−141.
1.3.
2007
Aav, R.; Kanger, T.; Pehk, T.; Lopp, M. (2007). Synthesis of substituted cyclopentanones from 2-oxabicyclo[3.3.0]oct-6-en-3-one. Proceedings of the Estonian Academy of Sciences. Chemistry, 56 (1), 3−13.
5.2.
2007
Aav, .; Kanger, T.; Pehk, T.; Lopp, M. (2007). Synthesis of Bicyclo[3.3.0]octanes – Interdediates for Substituted Cyclopentanes. Abstracts, 15th European Symposium on Organic Chemistry, 8-13 July 2007, Dublin, Ireland: 15th European Symposium on Organic Chemistry, Dublin, Ireland, 8-13 July 2007. Dublin: University College Dublin, 65.
5.2.
2007
Laars, M.; Kanger, T.; Kriis, K.; Lippur, K.; Lopp, M. (2007). Organocatalytic enantioselective transformations via diamines. 15th European Symposium On Organic Chemistry: 15th European Symposium On Organic Chemistry, ESOC15. 8th-13th July 2007, Dublin (Ireland).
1.1.
2006
Mosse, Sarah; Laars, Marju; Kriis, Kadri; Kanger, Tõnis; Alexakis, Alexandre (2006). 3,3’-Bimorpholine Derivatives as a New Class of Organocatalysts for Asymmetric Michael Addition. Organic Letters, 8 (12), 2559−2562.
1.1.
2006
Kriis, Kadri; Kanger, Tõnis; Laars, Marju; Kailas, Tiiu; Müürisepp, Aleksander-Mati; Pehk, Tõnis; Lopp, Margus (2006). Enantioselective Synthesis of Wieland-Miescher ketone through Bimorpholine-catalyzed Organocatalytic Aldol Condensation. Synlett, 11, 1699−1702.
1.1.
2006
Paju, Anne; Laos, Marit; Jõgi, Artur; Päri, Malle; Jäälaid, Raissa; Pehk, Tõnis; Kanger, Tõnis; Lopp, Margus (2006). Asymmetric synthesis of 2-alkyl-substituted 2-hydroxyglutaric acid γ-lactones. Tetrahedron Letters, 47 (26), 4491−4493.
1.1.
2006
Kanger, T.; Laars, M.; Kriis, K.; Kailas, T.; Müürisepp, A.-M.; Pehk, T.; Lopp, M. (2006). Anhimeric Assistance in the Case of vicinal Dimesylate: Formation of Enantiomeric or meso-Bimorpholine. Synthesis-Stuttgart, 11, 1853−1857.
1.1.
2006
Jõgi, Artur; Pehk, Tõnis; Kailas, Tiiu; Müürisepp, Aleksander-Mati; Kanger, Tõnis; Lopp, Margus (2006). Asymmetric synthesis of 2-phenyl-5-oxotetrahydrofuran-2-carboxylic acids. Synthesis-Stuttgart, 18, 3031−3036.
5.2.
2006
Mossé, S.; Laars, M.; Kanger, T.; Alexakis, A. (2006). 3,3’-Bimorpholine derivatives as a new class of organocatalysts for asymmetric Michael addition. BOS 2006 Abstracts: International Conference on Organic Synthesis-BOS 2006, Tallinn (Estonia), 25-29 June 2006. 122.
5.2.
2006
Kriis, K.; Kanger, T.; Laars, M.; Kailas, T.; Müürisepp, A-M.; Pehk, T.; Lopp, M. (2006). Bimorpholine as an organocatalyst for asymmetric aldol condensation. BOS 2006 Abstracts: International Conference on Organic Synthesis-BOS 2006, Tallinn (Estonia), 25-29 June 2006. 104.
1.1.
2005
Aav, Riina; Kanger, Tõnis; Pehk, Tõnis; Lopp, Margus (2005). Unexpected reactivity of ethyl 2-(diethylphosphono)propionate toward 2,2-disubstituted-1,3-cyclopentanediones. Phosphorus Sulfur and Silicon and the Related Elements, 180 (7), 1739−1748.
1.1.
2005
Kanger, Tõnis; Raudla, Kristin; Aav, Riina; Müürisepp, Aleksander-Mati; Pehk, Tõnis; Lopp, Margus (2005). Synthesis and derivatization of bis-nor Wieland-Miescher ketone. Synthesis-Stuttgart, 18, 3147−3151.
5.2.
2005
Laos, Marit; Jõgi, Artur; Paju, Anne; Kanger, Tõnis; Pehk, Tõnis; Lopp, Margus (2005). Asymmetric synthesis of 2-benzyl- and 2-benzyloxymethyl g-lactone acids. 14 th European Symposium on Organic Chemistry (ESOC14). Helsinki: TTY puuduv kirjastus, 309−309.
5.2.
2005
Laos, Marit; Paju, Anne; Kanger, Tõnis; Lopp, Margus; Pehk, Tõnis (2005). 3-bensüüloksümetüül-1,2-tsüklopentaandiooni süntees ja asümmeetriline oksüdatsioon = Synthesis and asymmetric oxidation of 3-benzyloxymethyl-1,2-cyclopentanedione. XXIX Eesti keemiapäevad : teaduskonverentsi ettekannete teesid = 29th Estonian Chemistry Days : abstracts of scientific conference. Tallinn: Tallinna Tehnikaülikooli Kirjastus, 52−53.
5.2.
2005
Raudla, K.; Kanger, T.; Müürisepp, A.; Pehk, T.; Lopp, M. (2005). Synthesis of bicyclo[3.3.0]octanone derivatives. 29th Estonian Chemistry Days, Abstracts of Scientific Conference. 94−95.
5.2.
2005
Laos, M.; Paju, A.; Kanger, T.; Lopp, M.; Pehk, T. (2005). Synthesis and asymmetric oxidation of 3-benzyloxymethyl-1,2-cyclopentanedione. 29th Estonian Chemistry Days, Abstracts of Scientific Conference. 52−53.
1.1.
2004
Kriis, K.; Kanger, T.; Lopp, M (2004). Asymmetric transfer hydrogenation of aromatic ketones by Rh(I)/bimorpholine complexes. Tetrahedron-Asymmetry, 15 (17), 2687−2691.
1.1.
2004
Paju, A.; Kanger, T.; Pehk, T.; Eek, M.; Lopp, M. (2004). A short enantioselective synthesis of homocitric acid-gamma-lactone and 4-hydroxy-homocitric acid-gamma-lactones. Tetrahedron, 60 (41), 9081−9084.
6.2.
2004
Kanger, T.; Laasik, M. (2004). Orgaanilise keemia praktikum : laboritehnika. Tallinn: Tallinna Tehnikaülikooli Kirjastus.
6.2.
2004
Kanger, T.; Laasik, M. (2004). Orgaanilise keemia praktikum : laboratoorsed tööd I. Tallinn: Tallinna Tehnikaülikooli Kirjastus.
1.1.
2003
Paju, Anne; Kanger, Tõnis; Pehk, Tõnis; Lindmaa, Rasmus; Müürisepp, Aleksander-Mati, Lopp, Margus. (2003). Asymmetric Oxidation of 3-Alkyl-1,2-cyclopentanediones. Part 2. Oxidative Ring Clevage of 3-Alkyl-1,2-cyclopentanediones: synthesis of 2-alkyl-γ-lactone acids. Tetrahedron-Asymmetry, 14 (11), 1565−1573.
1.1.
2003
Paju, Anne; Kanger, Tõnis; Niitsoo, Olivia; Pehk, Tõnis; Müürisepp, Aleksander-Mati; Lopp, Margus (2003). Asymmetric Oxidation of 3-Alkyl-1,2-cyclopentanediones. Part 3. Oxidative Ring Clevage of 3-Alkyl-1,2-cyclopentanediones: synthesis of α-hydroxy -γ-lactone acids and spiro-γ-dilactones. Tetrahedron-Asymmetry, 14 (16), 2393−2399.
1.1.
2003
Kanger, T.; Ausmees, K.; Muurisepp, AM.; Pehk, T.; Lopp, M (2003). A comparative study of the synthesis of C-2-symmetric chiral 2,2 '-biaziridinyls. Synlett, 7, 1055−1057.
1.1.
2003
Kriis, K.; Kanger, T.; Müürisepp, AM.; Lopp, M. (2003). C-2-Symmetric bimorpholines as chiral ligands in the asymmetric hydrogenation of ketones. Tetrahedron-Asymmetry, 14 (15), 2271−2275.
5.2.
2003
Kanger, Tõnis; Kriis, Kadri; Ausmees, Kerti; Pehk, Tõnis; Lopp, Margus (2003). C2-symmetric enantiomeric heterocycles : synthesis and application. 13th European Symposium on Organic Chemistry : September 10-15, 2003, Cavtat-Dubrovnik, Croatia : programme and abstracts. 342−342.
5.2.
2003
Paju, Anne; Kanger, Tõnis; Niitsoo, Olivia; Pehk, Tõnis; Müürisepp, Aleksander-Mati; Lopp, Margus (2003). Oxidative ring cleavage of 3-hydroxyethyl-1,2-cyclopentanediones : synthesis of 4-hydroxy-[??]-lactone acids and spiro-[??]-dilactones. Komppa Centenary Symposium : July 6-9, 2003, Espoo, Finland. TTY puuduv kirjastus, A73−A73.
1.1.
2002
Paju, Anne; Kanger, Tõnis; Pehk, Tõnis; Müürisepp, Aleksander-Mati; Lopp, Margus (2002). Asymmetric oxidation of 3-alkyl-1,2-cyclopentanediones. Part 1, 3-hydroxylation of 3-alkyl-1,2-cyclopentanediones. Tetrahedron : asymmetry, 2439−2448.
1.1.
2002
Paju, Anne; Kanger, Tõnis; Pehk, Tõnis; Lopp, Margus (2002). Direct asymmetric a-hydroxylation of 2-Hydroxymethylketones. Tetrahedron, 58 (36), 7321−7326.
1.1.
2002
Kanger, T.; Kriis, K.; Pehk, T.; Müürisepp, AM.; Lopp, M. (2002). Asymmetric synthesis of novel C-2-symmetric bimorpholines. Tetrahedron-Asymmetry, 13 (8), 857−865.
1.2.
2001
Lopp, M.; Paju, A.; Kanger, T.; Kriis, K.; Ilmarinen, K.; Pehk, T. (2001). Asymmetric Oxidation of Ketones. Proceedings of the Estonian Academy of Sciences. Chemistry, 50 (3), 124−137.
1.2.
2001
Kriis, K.; Kanger, T.; Pehk, T.; Lopp, M. (2001). Synthesis of (2S, 2S`)-bimorpholine. Proceedings of the Estonian Academy of Sciences. Chemistry, 50 (3), 173−179.
1.1.
2000
Aav, Riina; Kanger, Tõnis; Pehk, Tõnis; Lopp, Margus (2000). Synthesis of the AB-ring of 9,11-secosterols. Synlett, 4, 529−531.
1.1.
2000
Paju, Anne; Kanger, Tõnis; Pehk, Tõnis; Lopp, Margus (2000). Asymmetric oxidation of 1,2-cyclopentanediones. Tetrahedron Letters, 41 (35), 6883−6887.
1.1.
1999
Alexakis, A.; Aujard, I.; Kanger, T.; Magneney, P. (1999). (R, R)- and (S, S)-N, N’-Dimethyl-1,2-diphenylethylene1,2-diamine. Organic Synthesis, 76, 23−36.
1.1.
1999
Rose-Munch, Françoise; Gagliardini, Vanessa; Perrotey, Anne; Tranchier, Jean-Philippe; Rose, Eric; Mangeney, Pierre; Alexakis, Alexandre; Kanger, Tonis; Vaissermann, Jacqueline (1999). Two-step synthesis of homochiral monoaminals of tricarbonylphthalaldehydechromium complex. J.C.S.Chem.Comm., 20, 2061−2062.
1.1.
1998
Kanger, Tõnis; Niidas, Piret; Müürisepp, Aleksander-Mati; Pehk, Tõnis; Lopp, Margus (1998). Synthesis of chiral epoxyalkynes. Tetrahedron-Asymmetry, 9 (14), 2499−2508.
1.1.
1998
Kanger, T.; Kriis, K.; Paju, A.; Pehk, T.; Lopp, M (1998). Asymmetric oxidation of cyclobutanones: modification of the Sharpless catalyst. Tetrahedron-Asymmetry, 9 (24), 4475−4482.
1.1.
1997
Lopp, M.; Paju, A.; Kanger, T.; Pehk, T (1997). Direct Asymmetric -Hydroxylation of -Hydroxyketones. Tetrahedron Letters, 38 (28), 5051−5054.10.1016/S0040-4039(97)01102-7.
1.1.
1996
Lopp, M.; Paju, A.; Kanger, T.; Pehk, T. (1996). Aasymmetric Baeyer-Villiger oxidation of cyclobutanones. Tetrahedron Letters, 37 (42), 7583−7586.10.1016/0040-4039(96)01666-8.
1.1.
1995
Alexakis, A.; Kanger, T.; Mangeney, P.; Rose-Munch, F.; Perrotey, A.; Rose, E. (1995). Enantioselective ortho-Lithiation of Aminals of Benzaldehyde Chromiumtricarbonyl Complex. Tetrahedron-Asymmetry, 6 (1), 47−50.10.1016/0957-4166(94)00348-F.
1.1.
1995
Alexakis, A.; Kanger, T.; Mangeney, P.; Rose-Munch, F.; Perrotey, A.; Rose, E. (1995). Enantioselective ortho-Lithiation of Benzaldehyde Chromiumtricarbonyl Complex. Tetrahedron-Asymmetry, 6 (9), 2135−2138.10.1016/0957-4166(95)00283-U.
1.1.
1995
Kobzar, G.; Mardla, V.; Kanger, T.; Lopp, M.; Lille, Ü. (1995). Comparison of the anti-aggregatory activity of enantiomers of a 15-nonstereogenic carbacyclin analogue MM706. Pharmacology & Toxicology, 76, 297−298.
1.1.
1993
Kanger, T.; Liiv, M.; Pehk, T.; Lopp, M. (1993). A highly Stereoselective Synthesis of a New Propargylic Epoxide: (3R,4S)-1-tert-Butyldimethyl-silyl-3,4-epoxy-1-pentyne. Synthesis, 1, 91−93.
1.1.
1991
Lopp, M.; Kanger, T.; Müraus, A.; Pehk, T.; Lille, Ü. (1991). Synthesis of a Novel Four-carbon Chiron - (R)-1-t-Butyldimethylsilyl-3,4-Epoxy-but-1-yne. Tetrahedron-Asymmetry, 2 (10), 943−944.
1.2.
1989
Lopp M., Paju A., Kanger T., Välimäe T., Lille Ü. (1989). Synthesis of enynic and dienic Fragments of Leukotrienes and Pheromones. Zhurnal Organicheskoi Khimii, 25 (4), 869−870.

Tööstusomand

Tõnis Kanger

https://www.etis.ee/CV/Tõnis_Kanger/eng
6.05.1959
6204371
tonis.kanger@ttu.ee
http://
H-2462-2015

Career

Institution and occupation
01.01.2017–...   
Tallinn University of Technology , School of Science, Department of Chemistry and Biotechnology, Professor (1,00)
01.01.2017–...   
Tallinn University of Technology , School of Science, Dean (1,00)
1998- Tallinn University of Technology, associate professor
1990-1998 Institute of Chemistry, Tallinn, senior researcher
1993 University of P.M.Curie, Paris, post-doc
1982-1990 Institute of Chemistry, Tallinn, junior researcher
1988 Institute of Organic Chemistry, Warsaw, research fellow
01.09.2010–31.12.2016   
Tallinn University of Technology , Faculty of Science, dean (1,00)
2006–31.12.2016   
Tallinn University of Technology , Faculty of Science, Department of Chemistry, Chair of Organic Chemistry, Professor (1,00)
2005–2006   
Tallinn University of Technology , Faculty of Science, Department of Chemistry, Chair of Organic Chemistry, Associate Professor (1,00)
 
 
Education
1982 University of Tartu, organic chemistry
1977 Tallinn Secondary School No 2
 
 
R&D related managerial and administrative work
2016−...   
Member of the Commission for National Science Prizes
2013−...   
2012−...   
Member of the organizig committee of the conference "Balticum Organicum Syntheticum (BOS)"
2010−...   
Dean of Faculty of Science, TUT
2010−...   
Member of TUT council
2010−...   
Member of TUT governance
2008−...   
Member of the board of Faculty of Science, TUT
Member of Estonian Chemical Society
2013−2016   
Member of council of Institute of Cybernetics at TUT
2013−2015   
Scientific expert of the French National Research Agency (ANR)
2010−2014   
MC Member [CM0905 EE] of COST Action CM0905
2008−2010   
Member of the Expert Commission for Physical Sciences and Engineering of the Estonian Science Foundation
2008−2012   
Member of the board of Department of Chemistry, TUT
 
 
Creative work
Editor of textbook "Organic Chemistry", translated from F. C . Carey, R. M. Giuliano "Organic Chemistry, 8th edition, published by McGraw-Hill, 2011.
 
 
Additional career information
Courses at TUT: YKO0070 Organic Chemistry I, YKO5606 Organic Chemistry II , YKO0100 Methods of Chemical Synthesis, YKO5314 Organic Synthesis- Course Paper;

Qualifications

Academic degrees
Tõnis Kanger, Doctor's Degree, 1990, (sup) Margus Lopp; Ülo Lille, Bitsüklilised oksiraanid ja liitium/BF3 reagent prostaglandiinide enantiomeersete vaheühendite sünteesil (lithium alkynid-BF3 reagent and bicyclic oxiranes in the synthesis of enantiomeric intermediates of prostaglandins), Estonian Academy of Sciences.
 
 
Honours & awards
2016, Tõnis Kanger, National Research Award in chemistry and molecular biology
2004, Tõnis Kanger, Science Prize of Estonian Republic
 
 
Field of research
FIELD OF RESEARCH: 4. Natural Sciences and Engineering; 4.11. Chemistry and Chemical Technology; CERCS SPECIALTY: P390 Organic chemistry
 
 
Additional information
PhD
Institute of Chemistry, Tallinn, 1990

Projects in progress

Completed projects

Dissertations under supervision

Supervised dissertations

Publications

Category
Year
Publication
 
1.1.
2018
Trubitsõn, D.; Žari, S.; Kaabel, S.; Kudrjashova, M.; Kriis, K.; Järving, I.; Pehk, T.; Kanger, T. (2018). Asymmetric Organocatalytic Cascade Synthesis of Tetrahydro­furanyl Spirooxindoles. Synthesis, 50 (02), 314−322.10.1055/s-0036-1590918.
5.2.
2018
Murre, A.; Erkman, K.; Kanger, T. (2018). Diastereoselective Stevens [2,3]-Rearrangement of N-Allyl Ammonium Ylides. Balticum Organicum Syntheticum, July 1-4, 2108, Tallinn, Estonia. , 110.
1.1.
2017
Kriis, K.; Melnik, T.; Lips, K.; Juhanson, I.; Kaabel, S.; Järving, I.; Kanger, T. (2017). Asymmetric Synthesis of 2,3,4-Trisubstituted Piperidines. Synthesis, 49 (3), 604−614.10.1055/s-0036-1588299.
1.1.
2017
Ošeka, M.; Kimm, M.; Järving, I.; Lippur, K.; Kanger, T. (2017). Two Catalytic Methods of an Asymmetric Wittig [2,3]-Rearrangement. Journal of Organic Chemistry, 82 (6), 2889−2897.10.1021/acs.joc.6b02786.
1.1.
2017
Kaasik, M.; Kaabel, S.; Kriis, K.; Järving, I.; Aav, R.; Rissanen, K.; Kanger, T. (2017). Synthesis and Characterisation of Chiral Triazole-Based Halogen-Bond Donors: Halogen Bonds in the Solid State and in Solution. Chemistry - A European Journal, 23 (30), 7337−7344.10.1002/chem.201700618.
1.1.
2017
Metsala, A.; Žari, S.; Kanger, T. (2017). Reaction path scans: Aza-Michael reactions of isatin Imines. Computational and Theoretical Chemistry, 1117, 30−40.10.1016/j.comptc.2017.07.014.
1.1.
2017
Ben Moussa, S.; Lachheb, J.; Gruselle, M.; Maaten, B.; Kriis, K.; Kanger, T.; Tõnsuaadu, K.; Badraoui, B. (2017). Calcium, Barium and Strontium apatites: A new generation of catalysts in the Biginelli reaction. Tetrahedron, 73 (46), 6542−6548.10.1016/j.tet.2017.09.051.
5.2.
2017
Siim, E.; Gathergood, N.; Kanger, T. (2017). Catalysts derived from sustainable natural and value added alkaloids from poppies. In: .FMTDK Teaduskonverents, Tartu 07.03.2017-08.03.2017.
1.1.
2016
Ošeka, M.; Kimm, M.; Kaabel, S.; Järving, I.; Rissanen, K.; Kanger, T. (2016). Asymmetric Organocatalytic Wittig [2,3]-Rearrangement of Oxindoles. Organic Letters, 18 (6), 1358−1361.10.1021/acs.orglett.6b00291.
1.1.
2016
Metsala, A.; Žari, S.; Kanger, T. (2016). Aza-Michael Reactions of Isatin Imines: Deeper Insight and Origin of the Stereoselectivity. ChemCatChem, 8 (18), 2961−2967.10.1002/cctc.201600584.
5.2.
2016
Lippur, K.; Kanger, T. (2016). Asymmetric Ca-Catalyzed Wittig [2,3]-Rearrangement of Allyloxy 1,3-Dicarbonyl Compounds. Balticum Organicum Syntheticum, Riga, Latvia, July 3-6, 2016. -, 106.
5.2.
2016
Trubitsõn, D.; Žari, S.; Kudrjashova, M.; Lippur, K.; Ošeka, M.; Kanger, T. (2016). Enantioselective Organocatalytic Synthesis of Oxa-Spirooxindole Derivatives. Balticum Organicum Syntheticum, Riga, Latvia, July 3-6, 2016. -, 161.
1.1.
2015
Lippur, K.; Kaabel, S.; Järving, I.; Rissanen, K.; Kanger, T. (2015). CaCl2, Bisoxazoline, and Malonate: A Protocol for an Asymmetric Michael Reaction. Journal of Organic Chemistry, 80 (12), 6336−6341.10.1021/acs.joc.5b00769.
1.1.
2015
Kaasik, M.; Noole, A.; Reitel, K.; Järving, I.; Kanger, T. (2015). Organocatalytic Conjugate Addition of Cyclopropylacetaldehyde Derivatives to Nitro Olefins: en Route to β- and γ-Amino Acids. European Journal of Organic Chemistry, 8, 1745−1753.10.1002/ejoc.201403387.
1.1.
2015
Žari, S.; Metsala, A.; Kudrjashova, M.; Kaabel, S.; Järving, I.; Kanger, T. (2015). Asymmetric Organocatalytic Aza-Michael Reactions of Isatin Derivatives. Synthesis, 47 (6), 875−886.10.1055/s-0034-1379956.
1.1.
2015
Preegel, Gert; Ilmarinen, Kaja; Järving, Ivar; Kanger, Tõnis; Pehk, Tõnis; Lopp, Margus (2015). Enantioselective Organocatalytic Michael Addition-Cyclization Cascade of Cyclopentane-1,2-dione with Substituted (E)-2-oxobut-3-enoates. Synthesis, 3805−3812.
1.1.
2015
Paju, A.; Kostromarova, D.; Matkevitš, K.; Laos, M.; Pehk, T.; Kanger, T.; Lopp, M. (2015). 3-Alkyl-1,2-cyclopentanediones by Negishi cross-coupling of a 3-bromo-1,2-cyclopentanedione silyl enol ether with alkylzinc reagents: an approach to 2-substituted carboxylic acid gamma-lactones, homocitric and lycoperdic acids. Tetrahedron, 71 (49), 9313−9320.10.1016/j.tet.2015.10.014.
1.1.
2014
Paju, A.; Kanger, T.; Müürisepp, A-M.; Aid, T.; Pehk, T.; Lopp, M. (2014). Sonogashira cross-coupling of 3-bromo-1,2-diones: an access to 3-alkynyl-1,2-diones. Tetrahedron, 70 (35), 5843−5848.10.1016/j.tet.2014.06.037.
1.1.
2014
Preegel, G.; Noole, A.; Ilmarinen, K.; Järving, I.; Kanger, T.; Pehk, T.; Lopp, M. (2014). Enantioselective Organocatalytic Michael Addition of Cyclopentane-1,2-diones to Nitroolefins. Synthesis, 46 (19), 2595−2600.10.1055/s-0034-1378374.
1.1.
2014
Kreek, K.; Kriis, K.; Maaten, B.; Uibu, M.; Mere, A.; Kanger, T.; Koel, M. (2014). Organic and carbon aerogels containing rare-earth metals: Their properties and application as catalysts. Journal of Non-Crystalline Solids, 404, 43−48.10.1016/j.jnoncrysol.2014.07.021.
1.1.
2014
Maaten, B.; Moussa, J.; Desmarets, C.; Gredin, P.; Beaunier, P.; Kanger, T.; Tõnsuaadu, K.; Villemin, D.; Gruselle, M. (2014). Cu-Modified Hydroxy-Apatite as Catalyst for Glaser-Hay C-C Homo- Coupling Reaction of Terminal Alkynes. Journal of Molecular Catalysis A: Chemical, 393, 112−116.doi:10.1016/j.molcata.2014.06.011.
1.1.
2014
Ošeka, M.; Noole, A.; Žari, S.; Öeren, M.; Lopp, M.; Kanger, T. (2014). Asymmetric Diastereoselective Synthesis of Spirocyclopropane Derivatives of Oxindole. European Journal of Organic Chemistry, 2014 (17), 3599−3606.
1.1.
2014
Žari, S.; Kudrjashova, M.; Pehk, T.; Lopp, M.; Kanger, T. (2014). Remote Activation of the Nucleophilicity of Isatin. Organic Letters, 16 (6), 1740−1743.10.1021/ol500421k.
5.2.
2014
Kudrjashova, M.; Žari, S.; Pehk, T.; Kanger, T. (2014). NMR study of the remote activation of the nucleophilicity of isatin imines. 8th Biennal International Conference on Organic Synthesis - Balticum Organicum Syntheticum (BOS2014). July 6-9, 2014, Vilnius. 87.
5.2.
2014
Preegel, G.; Noole, A.; Kanger, T.; Pehk, T.; Lopp, M. (2014). Enantioselective organocatalytic Michael addition of cyclopentane-1,2-diones to electrophiles. Balticum Organicum Syntheticum, Vilnius, Lithuania, July 6-9.
5.2.
2014
Kriis, K.; Ausmees, K.; Plado, A.; Pehk, T.; Lopp, M.; Kanger, T. (2014). Diastereoselective multicomponent cascade reaction for the synthesis of heterobicyclic heptanes. Program and Abstract Book of 8th Biennial International Conference on Organic Synthesis: Balticum Organicum Syntheticum, Vilnius, July 6-9, 2014.
5.2.
2014
Noole, A.; Kanger, T.. (2014). Asymmetric synthesis of congested spiro-cyclopentaneoxindoles via an organocatalytic cascade reaction. 248th ACS National Meeting & Exposition, USA, San Fransisco, CA, 2014. American Chemical Society,.
5.2.
2014
Noole, A.; Ošeka, M.; Malkov, A.; Lopp, M.; Kanger, T. (2014). Asymmetric organocatalytic synthesis of spiro-cyclopropyloxindoles. Balticum Organicum Syntheticum: International Conference on Organic Synthesis 2014, Lithuania, Vilnius, July 6-9, 2014.
5.2.
2014
Lippur, K.; Lopp, M.; Kanger, T. (2014). Calcium-catalyzed asymmetric reactions of 1,3-dicarbonyl compounds. 8th Biennial International Conference on Organic Synthesis, Balticum Organicum Syntheticum, July 6-9, 2014, Vilnius. -, 94.
1.1.
2013
Reitel, K.; Lippur, K.; Järving, I.; Kudrjašova, M.; Lopp, M.; Kanger, T. (2013). Asymmetric Aminocatalytic Michael Addition of Cyclopropane-Containing Aldehydes to Nitroalkenes. Synthesis, 45 (19), 2679−2683.10.1055/s-0033-1338704.
1.1.
2013
Noole, A.; Malkov, A. V.; Kanger, T.. (2013). Asymmetric Organocatalytic Synthesis of Spiro-cyclopropaneoxindoles. Synthesis, 45 (18), 2520−2524.
1.1.
2013
Noole, A.; Ilmarinen, K.; Järving, I.; Lopp, M.; Kanger, T. (2013). Asymmetric Synthesis of Congested Spiro-cyclopentaneoxindoles via an Organocatalytic Cascade Reaction. Journal of Organic Chemistry, 78 (16), 8117−8122.10.1021/jo4008223.
1.1.
2013
Noole, Artur; Ošeka, Maksim; Pehk, Tõnis; Öeren, Mario; Järving, Ivar; Elsegood, Mark; Malkov, Andrei; Lopp, Margus; Kanger, Tõnis. (2013). 3-Chlorooxindoles: Versatile Starting Materials for Asymmetric Organocatalytic Synthesis of Spirooxindoles. Advanced Synthesis and Catalysis, 355 (5), 829−835.
5.2.
2013
Preegel, G.; Noole, A.; Kanger, T.; Lopp, M. (2013). Enantioselective organocatalytic Michael addition of cyclopentane-1,2-diones to nitro olefins. ESOC 2013, Marseille, France, July 7-12.
5.2.
2013
Reitel, K.; Lippur, K.; Järving, I.; Kudrjašova, M.; Lopp, M.; Kanger, T. (2013). Aminocatalytic Michael addition of cyclopropane-containing aldehydes to nitroolefines. ESOC Marseille, France July 7-12.
5.2.
2013
Tõnsuaadu, K.; Gruselle, M.; Moussa, J.; Villemin, D.; Maaten, B.; Kanger, T. (2013). Modified calcium apatites as new catalysts in organic synthesis. International Symposium on Inorganic and Environmental Materials 2013, Programm and abstracts, October 27-31, 2013, Rennes, France. 277.
1.1.
2012
Noole, A.; Järving, I.; Werner, F.; Lopp, M.; Malkov, A.; Kanger, T. (2012).

Organocatalytic Asymmetric Synthesis of 3-Chlorooxindoles Bearing Adjacent Quaternary–Tertiary Centers

. Organic Letters, 14 (18), 4922−4925.10.1021/ol302245b.
1.1.
2012
Lippur, K.; Tiirik, T.; Kudrjashova, M.; Järving, I.; Lopp, M.; Kanger, T. (2012). Amination of quinolones with morpholine derivatives. Tetrahedron, 68 (47), 9550−9555.10.1016/j.tet.2012.09.082.
1.1.
2012
Žari, S.; Kailas, T.; Kudrjashova, M.; Öeren, M.; Järving, I.; Tamm, T.; Lopp, M.; Kanger, T. (2012). Organocatalytic asymmetric addition of malonates to unsaturated 1,4-diketones. Beilstein Journal of Organic Chemistry, 8, 1452−1457.
1.1.
2012
Reinart-Okugbeni, Reet; Ausmees, Kerti; Kriis, Kadri; Rinken, Ago; Kanger, Tõnis (2012). Chemoenzymatic synthesis and evaluation of 3-azabicyclo[3.2.0]heptane derivatives as dopaminergic ligands. European Journal of Medicinal Chemistry, 55, 255−261.10.1016/j.ejmech.2012.07.025.
1.1.
2012
Reile, I.; Paju, A.; Kanger, T.; Järving, I.; Lopp, M. (2012). Cyclopentane-1,2-dione bis(tert-butyldimethylsilyl) enol ether in asymmetric organocatalytic Mukaiyama–Michael reactions. Tetrahedron Letters, 53 (12), 1476−1478.10.1016/j.tetlet.2012.01.041.
1.1.
2012
Noole, A.; Pehk, T.; Järving, I.; Lopp, M.; Kanger, T. (2012). Organocatalytic asymmetric synthesis of trisubstituted pyrrolidines via a cascade reaction. Tetrahedron-Asymmetry, 23 (2), 188−198.10.1016/j.tetasy.2012.01.021.
1.1.
2012
Ausmees, K.; Kriis, K.; Pehk, T.; Werner, F.; Järving, I.; Lopp, M.; Kanger, T. (2012). Diastereoselective Multicomponent Cascade Reaction Leading to [3.2.0]-Heterobicyclic Compounds. Journal of Organic Chemistry, 77 (23), 10680−10687.10.1021/jo3019413.
1.1.
2012
Noole, A.; Suckman, N.; Kabeshov, M.; Kanger, T.; Macaev, F.; Malkov, A. (2012). Highly Enantio- and Diastereoselective Generation of Two Quaternary Centers in Spirocyclopropanation of Oxindole Derivatives. Chemistry - A European Journal, 18 (47), 14929−14933.10.1002/chem.201203099.
5.2.
2012
Gruselle, M.; Kanger, T.; Flambard, A.; Kriis, K.; Mikli, V.; Maaten, B.; Tonsuaadu, K. (2012). Calcium fluor- and hydroxy-apatites modified or not as catalysts for C-C bond formation. Book of Abstracts: Catalysis in Organic Synthesis: Catalysis in Organic Synthesis, September 15-20, 2012, Moscow, Russia. Moscow, Russia, 190.
5.2.
2012
Lippur, K.; Tiirik, T.; Kudrjašova, M.; Lopp, M.; Kanger, T. (2012). Amination of Quinolones. Balticum Organicum Syntheticum 2012 : abstracts: The 7th Biannual international conference on organic synthesis, Tallinn, Estonia. 1-4th of July 2012.
5.2.
2012
Kriis, K.; Ausmees, K.; Pehk, T.; Lopp, M.; Kanger, T. (2012). Diastereoselective multicomponent cascade reaction leading to heterobicyclic heptanes. 13th Florida Heterocyclic and Synthetic Conference: FloHet-2012, Florida, March 4-6, 2012.
5.2.
2012
Reitel, K.; Kudrjašova, M.; Lopp, M.; Kanger, T. (2012). Cyclopropane-containing compounds in organocatalytic Michael reaction. Balticum Organicum Syntheticum 2012, Tallinn, 1-4 July 2012. , 2012..
1.1.
2011
Ausmees, K.; Selyutina, A.; Kütt, K.; Lippur, K.; Pehk, T.; Lopp, M.; Žusinaite, E.; Merits, A.; Kanger, T. (2011). Synthesis and biological activity of bimorpholine and its carbanucleoside. Nucleosides Nucleotides & Nucleic Acids, 30 (11), 897−907.10.1080/15257770.2011.621919.
1.1.
2011
Gruselle, M.; Kanger, T.; Thouvenot, R.; Flambard, A.; Kriis, K.; Mikli, V.; Traksmaa, R.; Maaten, B.; Tõnsuaadu, K. (2011). Calcium Hydroxyapatites as Efficient Catalysts for the Michael CC Bond Formation. ACS Catalysis, 1729−1733.10.1021/cs200460k.
1.1.
2011
Laars, M.; Ausmees, K.; Kudrjashova, M.; Kanger, T.; Werner, F. (2011). rac -2,2’-Bipiperidine-1,1’-diium dibromide. Acta Crystallographica Section E: Structure Reports Online, 67 (6), o1324.10.1107/S1600536811016084.
1.1.
2011
Noole, A.; Borissova, M.; Lopp, M.; Kanger, T. (2011). Enantioselective Organocatalytic Aza-Ene-Type Domino Reaction Leading to 1,4-Dihydropyridines. Journal of Organic Chemistry, 76 (6), 1538−1545.10.1021/jo200095e.
1.1.
2010
Laars, M.; Raska, H.; Lopp, M.; Kanger, T. (2010). Cyclic amino acid salts as catalysts for the asymmetric Michael reaction. Tetrahedron-Asymmetry, 21 (5), 562−565.10.1016/j.tetasy.2010.02.025.
1.1.
2010
Kriis, K.; Ausmees, K.; Pehk, T.; Lopp, M.; Kanger, T. (2010). A Novel Diastereoselective Multicomponent Cacade Reaction. Organic Letters, 12 (10), 2230−2233.10.1021/ol1005714.
1.1.
2010
Noole, A.; Lippur, K.; Metsala, A.; Lopp, M.; Kanger, T.. (2010). Enantioselective Henry Reaction Catalyzed by CuII Salt and Bipiperidine. Journal of Organic Chemistry, 75 (4), 1313−1316.10.1021/jo902664v.
1.1.
2010
Uudsemaa, M.; Kanger, T.; Lopp, M.; Tamm, T. (2010). pKa calculation for monoprotonated bipiperidine, bimorpholine and their derivatives in H2O and MeCN. Chemical Physics Letters, 485, 83−86.10.1016/j.cplett.2009.12.006.
1.1.
2010
Lippur, K.; Elmers, C.; Kailas, T.; Müürisepp, A-M.; Pehk, T.; Kanger, T.; Lopp, M. (2010). Synthesis of 5,5'-disubstituted bimorpholines. Synthetic Communications, 40 (2), 266−281.10.1080/00397910902964874.
5.2.
2010
Lippur, K.; Merits, A.; Lopp, M.; Kanger, T. (2010). Synthesis of 2,2’-bimorpholines and their biological activity. Balticum Organicum Syntheticum 2010, Riga, 27-30 June 2010.
5.2.
2010
Kriis, K.; Ausmees, K.; Pehk, T.; Lopp, M.; Kanger, T. (2010). A novel diastereoselective multicomponent cascade reaction. Program and Abstracts BOS 2010 International Conference on Organic Synthesis: BOS 2010 International Conference on Organic Synthesis, Riga - Latvia, June 27 - 30, 2010. 117.
5.2.
2010
Reitel, K.; Lopp, M.; Kanger, T. (2010). Synthesis of ILS (S,S')-bipiperidine derivatives and their application as organocatalysts. Balticum Organicum Syntheticum 2010, Riga, 27-30 June 2010. , 2010..
6.2.
2010
Kanger, T. (2010). Orgaanilise keemia nomenklatuuri põhimõtted. Tallinna Tehnikaülikooli Kirjastus.
1.1.
2009
Laars, M.; Ausmees, K.; Uudsemaa, M.; Tamm, T.; Kanger, T.; Lopp, M. (2009). Enantioselective Organocatalytic Michael Addition of Aldehydes to β-Nitrostyrenes. Journal of Organic Chemistry, 74 (10), 3772−3775.10.1021/jo900322h.
1.1.
2009
Uudsemaa, M.; Laars, M.; Kriis, K.; Tamm, T.; Lopp, M.; Kanger, T. (2009). Influence of protonation upon the conformations of bipiperidine, bimorpholine, and their derivatives. Chemical Physics Letters, 417, 92−96.10.1016/j.cplett.2009.02.027.
5.2.
2009
Noole, A.; Kanger, T. (2009). Synthesis of 2-(2'-piperidinyl)pyridine derivatives and their use as ligands in asymmetric Henry and aza-Henry reactions. 16th European Symposium on Organic Chemistry (ESOC 2009), Praha, 12-16 juuli. 422.
6.2.
2009
Kanger, T.; Laasik, M. (2009). Orgaanilise keemia praktikum. Laboratoorsed tööd I. Tallinna Tehnikaülikooli Kirjastus.
1.1.
2008
Laars, M.; Kriis, K.; Kailas, T.; Müürisepp, A.M.; Pehk, T.; Kanger, T.; Lopp, M. (2008). Structural constraints for C-2-symmetric heterocyclic organocatalysts in asymmetric aldol reactions. Tetrahedron-Asymmetry, 19 (6), 641−645.
5.2.
2008
Aav, R.; Kanger, T.; Lopp, M. (2008). Synthesis of 9,11-secosterol D-ring synthon. International Conference on Organic Synthesis-BOS2008, Vilnius 2008: Balticum Organicum Syntheticum 2008, Vilnius.
1.1.
2007
Sulzer-Mossé, S.; Laars, M.; Kriis, K.; Kanger, T.; Alexakis, A. (2007). Synthesis and Use of 3,3’-Bimorpholine Derivatives in Asymmetric Michael Addition and Intramolecular Aldol Reaction. Synthesis, 11, 1729−1732.
1.1.
2007
Kanger, T.; Kriis, K.; Laars, M.; Kailas, T.; Müürisepp, A-M.; Pehk, T.; Lopp, M. (2007). Bimorpholine-Mediated Enantioselective Intramolecular and Intermolecular Aldol Condensation. Journal of Organic Chemistry, 72, 5168−5173.
1.1.
2007
Kriis, K.; Laars, M.; Lippur, K.; Kanger, T. (2007). Bimorpholines as Alternative Organocatalysts in Asymmetric Aldol Reaction. Chimia, 61 (5), 232−235.
1.1.
2007
Lippur, K.; Kanger, T.; Kriis, K.; Kailas, T.; Müürisepp, A-M.; Pehk, T.; Lopp, M. (2007). Synthesis of (2S,2’S)-bimorpholine N,N’-quaternary salts as chiral phase transfer catalysts. Tetrahedron-Asymmetry, 18 (1), 137−141.
1.3.
2007
Aav, R.; Kanger, T.; Pehk, T.; Lopp, M. (2007). Synthesis of substituted cyclopentanones from 2-oxabicyclo[3.3.0]oct-6-en-3-one. Proceedings of the Estonian Academy of Sciences. Chemistry, 56 (1), 3−13.
5.2.
2007
Aav, .; Kanger, T.; Pehk, T.; Lopp, M. (2007). Synthesis of Bicyclo[3.3.0]octanes – Interdediates for Substituted Cyclopentanes. Abstracts, 15th European Symposium on Organic Chemistry, 8-13 July 2007, Dublin, Ireland: 15th European Symposium on Organic Chemistry, Dublin, Ireland, 8-13 July 2007. Dublin: University College Dublin, 65.
5.2.
2007
Laars, M.; Kanger, T.; Kriis, K.; Lippur, K.; Lopp, M. (2007). Organocatalytic enantioselective transformations via diamines. 15th European Symposium On Organic Chemistry: 15th European Symposium On Organic Chemistry, ESOC15. 8th-13th July 2007, Dublin (Ireland).
1.1.
2006
Mosse, Sarah; Laars, Marju; Kriis, Kadri; Kanger, Tõnis; Alexakis, Alexandre (2006). 3,3’-Bimorpholine Derivatives as a New Class of Organocatalysts for Asymmetric Michael Addition. Organic Letters, 8 (12), 2559−2562.
1.1.
2006
Kriis, Kadri; Kanger, Tõnis; Laars, Marju; Kailas, Tiiu; Müürisepp, Aleksander-Mati; Pehk, Tõnis; Lopp, Margus (2006). Enantioselective Synthesis of Wieland-Miescher ketone through Bimorpholine-catalyzed Organocatalytic Aldol Condensation. Synlett, 11, 1699−1702.
1.1.
2006
Paju, Anne; Laos, Marit; Jõgi, Artur; Päri, Malle; Jäälaid, Raissa; Pehk, Tõnis; Kanger, Tõnis; Lopp, Margus (2006). Asymmetric synthesis of 2-alkyl-substituted 2-hydroxyglutaric acid γ-lactones. Tetrahedron Letters, 47 (26), 4491−4493.
1.1.
2006
Kanger, T.; Laars, M.; Kriis, K.; Kailas, T.; Müürisepp, A.-M.; Pehk, T.; Lopp, M. (2006). Anhimeric Assistance in the Case of vicinal Dimesylate: Formation of Enantiomeric or meso-Bimorpholine. Synthesis-Stuttgart, 11, 1853−1857.
1.1.
2006
Jõgi, Artur; Pehk, Tõnis; Kailas, Tiiu; Müürisepp, Aleksander-Mati; Kanger, Tõnis; Lopp, Margus (2006). Asymmetric synthesis of 2-phenyl-5-oxotetrahydrofuran-2-carboxylic acids. Synthesis-Stuttgart, 18, 3031−3036.
5.2.
2006
Mossé, S.; Laars, M.; Kanger, T.; Alexakis, A. (2006). 3,3’-Bimorpholine derivatives as a new class of organocatalysts for asymmetric Michael addition. BOS 2006 Abstracts: International Conference on Organic Synthesis-BOS 2006, Tallinn (Estonia), 25-29 June 2006. 122.
5.2.
2006
Kriis, K.; Kanger, T.; Laars, M.; Kailas, T.; Müürisepp, A-M.; Pehk, T.; Lopp, M. (2006). Bimorpholine as an organocatalyst for asymmetric aldol condensation. BOS 2006 Abstracts: International Conference on Organic Synthesis-BOS 2006, Tallinn (Estonia), 25-29 June 2006. 104.
1.1.
2005
Aav, Riina; Kanger, Tõnis; Pehk, Tõnis; Lopp, Margus (2005). Unexpected reactivity of ethyl 2-(diethylphosphono)propionate toward 2,2-disubstituted-1,3-cyclopentanediones. Phosphorus Sulfur and Silicon and the Related Elements, 180 (7), 1739−1748.
1.1.
2005
Kanger, Tõnis; Raudla, Kristin; Aav, Riina; Müürisepp, Aleksander-Mati; Pehk, Tõnis; Lopp, Margus (2005). Synthesis and derivatization of bis-nor Wieland-Miescher ketone. Synthesis-Stuttgart, 18, 3147−3151.
5.2.
2005
Laos, Marit; Jõgi, Artur; Paju, Anne; Kanger, Tõnis; Pehk, Tõnis; Lopp, Margus (2005). Asymmetric synthesis of 2-benzyl- and 2-benzyloxymethyl g-lactone acids. 14 th European Symposium on Organic Chemistry (ESOC14). Helsinki: TTY puuduv kirjastus, 309−309.
5.2.
2005
Laos, Marit; Paju, Anne; Kanger, Tõnis; Lopp, Margus; Pehk, Tõnis (2005). 3-bensüüloksümetüül-1,2-tsüklopentaandiooni süntees ja asümmeetriline oksüdatsioon = Synthesis and asymmetric oxidation of 3-benzyloxymethyl-1,2-cyclopentanedione. XXIX Eesti keemiapäevad : teaduskonverentsi ettekannete teesid = 29th Estonian Chemistry Days : abstracts of scientific conference. Tallinn: Tallinna Tehnikaülikooli Kirjastus, 52−53.
5.2.
2005
Raudla, K.; Kanger, T.; Müürisepp, A.; Pehk, T.; Lopp, M. (2005). Synthesis of bicyclo[3.3.0]octanone derivatives. 29th Estonian Chemistry Days, Abstracts of Scientific Conference. 94−95.
5.2.
2005
Laos, M.; Paju, A.; Kanger, T.; Lopp, M.; Pehk, T. (2005). Synthesis and asymmetric oxidation of 3-benzyloxymethyl-1,2-cyclopentanedione. 29th Estonian Chemistry Days, Abstracts of Scientific Conference. 52−53.
1.1.
2004
Kriis, K.; Kanger, T.; Lopp, M (2004). Asymmetric transfer hydrogenation of aromatic ketones by Rh(I)/bimorpholine complexes. Tetrahedron-Asymmetry, 15 (17), 2687−2691.
1.1.
2004
Paju, A.; Kanger, T.; Pehk, T.; Eek, M.; Lopp, M. (2004). A short enantioselective synthesis of homocitric acid-gamma-lactone and 4-hydroxy-homocitric acid-gamma-lactones. Tetrahedron, 60 (41), 9081−9084.
6.2.
2004
Kanger, T.; Laasik, M. (2004). Orgaanilise keemia praktikum : laboritehnika. Tallinn: Tallinna Tehnikaülikooli Kirjastus.
6.2.
2004
Kanger, T.; Laasik, M. (2004). Orgaanilise keemia praktikum : laboratoorsed tööd I. Tallinn: Tallinna Tehnikaülikooli Kirjastus.
1.1.
2003
Paju, Anne; Kanger, Tõnis; Pehk, Tõnis; Lindmaa, Rasmus; Müürisepp, Aleksander-Mati, Lopp, Margus. (2003). Asymmetric Oxidation of 3-Alkyl-1,2-cyclopentanediones. Part 2. Oxidative Ring Clevage of 3-Alkyl-1,2-cyclopentanediones: synthesis of 2-alkyl-γ-lactone acids. Tetrahedron-Asymmetry, 14 (11), 1565−1573.
1.1.
2003
Paju, Anne; Kanger, Tõnis; Niitsoo, Olivia; Pehk, Tõnis; Müürisepp, Aleksander-Mati; Lopp, Margus (2003). Asymmetric Oxidation of 3-Alkyl-1,2-cyclopentanediones. Part 3. Oxidative Ring Clevage of 3-Alkyl-1,2-cyclopentanediones: synthesis of α-hydroxy -γ-lactone acids and spiro-γ-dilactones. Tetrahedron-Asymmetry, 14 (16), 2393−2399.
1.1.
2003
Kanger, T.; Ausmees, K.; Muurisepp, AM.; Pehk, T.; Lopp, M (2003). A comparative study of the synthesis of C-2-symmetric chiral 2,2 '-biaziridinyls. Synlett, 7, 1055−1057.
1.1.
2003
Kriis, K.; Kanger, T.; Müürisepp, AM.; Lopp, M. (2003). C-2-Symmetric bimorpholines as chiral ligands in the asymmetric hydrogenation of ketones. Tetrahedron-Asymmetry, 14 (15), 2271−2275.
5.2.
2003
Kanger, Tõnis; Kriis, Kadri; Ausmees, Kerti; Pehk, Tõnis; Lopp, Margus (2003). C2-symmetric enantiomeric heterocycles : synthesis and application. 13th European Symposium on Organic Chemistry : September 10-15, 2003, Cavtat-Dubrovnik, Croatia : programme and abstracts. 342−342.
5.2.
2003
Paju, Anne; Kanger, Tõnis; Niitsoo, Olivia; Pehk, Tõnis; Müürisepp, Aleksander-Mati; Lopp, Margus (2003). Oxidative ring cleavage of 3-hydroxyethyl-1,2-cyclopentanediones : synthesis of 4-hydroxy-[??]-lactone acids and spiro-[??]-dilactones. Komppa Centenary Symposium : July 6-9, 2003, Espoo, Finland. TTY puuduv kirjastus, A73−A73.
1.1.
2002
Paju, Anne; Kanger, Tõnis; Pehk, Tõnis; Müürisepp, Aleksander-Mati; Lopp, Margus (2002). Asymmetric oxidation of 3-alkyl-1,2-cyclopentanediones. Part 1, 3-hydroxylation of 3-alkyl-1,2-cyclopentanediones. Tetrahedron : asymmetry, 2439−2448.
1.1.
2002
Paju, Anne; Kanger, Tõnis; Pehk, Tõnis; Lopp, Margus (2002). Direct asymmetric a-hydroxylation of 2-Hydroxymethylketones. Tetrahedron, 58 (36), 7321−7326.
1.1.
2002
Kanger, T.; Kriis, K.; Pehk, T.; Müürisepp, AM.; Lopp, M. (2002). Asymmetric synthesis of novel C-2-symmetric bimorpholines. Tetrahedron-Asymmetry, 13 (8), 857−865.
1.2.
2001
Lopp, M.; Paju, A.; Kanger, T.; Kriis, K.; Ilmarinen, K.; Pehk, T. (2001). Asymmetric Oxidation of Ketones. Proceedings of the Estonian Academy of Sciences. Chemistry, 50 (3), 124−137.
1.2.
2001
Kriis, K.; Kanger, T.; Pehk, T.; Lopp, M. (2001). Synthesis of (2S, 2S`)-bimorpholine. Proceedings of the Estonian Academy of Sciences. Chemistry, 50 (3), 173−179.
1.1.
2000
Aav, Riina; Kanger, Tõnis; Pehk, Tõnis; Lopp, Margus (2000). Synthesis of the AB-ring of 9,11-secosterols. Synlett, 4, 529−531.
1.1.
2000
Paju, Anne; Kanger, Tõnis; Pehk, Tõnis; Lopp, Margus (2000). Asymmetric oxidation of 1,2-cyclopentanediones. Tetrahedron Letters, 41 (35), 6883−6887.
1.1.
1999
Alexakis, A.; Aujard, I.; Kanger, T.; Magneney, P. (1999). (R, R)- and (S, S)-N, N’-Dimethyl-1,2-diphenylethylene1,2-diamine. Organic Synthesis, 76, 23−36.
1.1.
1999
Rose-Munch, Françoise; Gagliardini, Vanessa; Perrotey, Anne; Tranchier, Jean-Philippe; Rose, Eric; Mangeney, Pierre; Alexakis, Alexandre; Kanger, Tonis; Vaissermann, Jacqueline (1999). Two-step synthesis of homochiral monoaminals of tricarbonylphthalaldehydechromium complex. J.C.S.Chem.Comm., 20, 2061−2062.
1.1.
1998
Kanger, Tõnis; Niidas, Piret; Müürisepp, Aleksander-Mati; Pehk, Tõnis; Lopp, Margus (1998). Synthesis of chiral epoxyalkynes. Tetrahedron-Asymmetry, 9 (14), 2499−2508.
1.1.
1998
Kanger, T.; Kriis, K.; Paju, A.; Pehk, T.; Lopp, M (1998). Asymmetric oxidation of cyclobutanones: modification of the Sharpless catalyst. Tetrahedron-Asymmetry, 9 (24), 4475−4482.
1.1.
1997
Lopp, M.; Paju, A.; Kanger, T.; Pehk, T (1997). Direct Asymmetric -Hydroxylation of -Hydroxyketones. Tetrahedron Letters, 38 (28), 5051−5054.10.1016/S0040-4039(97)01102-7.
1.1.
1996
Lopp, M.; Paju, A.; Kanger, T.; Pehk, T. (1996). Aasymmetric Baeyer-Villiger oxidation of cyclobutanones. Tetrahedron Letters, 37 (42), 7583−7586.10.1016/0040-4039(96)01666-8.
1.1.
1995
Alexakis, A.; Kanger, T.; Mangeney, P.; Rose-Munch, F.; Perrotey, A.; Rose, E. (1995). Enantioselective ortho-Lithiation of Aminals of Benzaldehyde Chromiumtricarbonyl Complex. Tetrahedron-Asymmetry, 6 (1), 47−50.10.1016/0957-4166(94)00348-F.
1.1.
1995
Alexakis, A.; Kanger, T.; Mangeney, P.; Rose-Munch, F.; Perrotey, A.; Rose, E. (1995). Enantioselective ortho-Lithiation of Benzaldehyde Chromiumtricarbonyl Complex. Tetrahedron-Asymmetry, 6 (9), 2135−2138.10.1016/0957-4166(95)00283-U.
1.1.
1995
Kobzar, G.; Mardla, V.; Kanger, T.; Lopp, M.; Lille, Ü. (1995). Comparison of the anti-aggregatory activity of enantiomers of a 15-nonstereogenic carbacyclin analogue MM706. Pharmacology & Toxicology, 76, 297−298.
1.1.
1993
Kanger, T.; Liiv, M.; Pehk, T.; Lopp, M. (1993). A highly Stereoselective Synthesis of a New Propargylic Epoxide: (3R,4S)-1-tert-Butyldimethyl-silyl-3,4-epoxy-1-pentyne. Synthesis, 1, 91−93.
1.1.
1991
Lopp, M.; Kanger, T.; Müraus, A.; Pehk, T.; Lille, Ü. (1991). Synthesis of a Novel Four-carbon Chiron - (R)-1-t-Butyldimethylsilyl-3,4-Epoxy-but-1-yne. Tetrahedron-Asymmetry, 2 (10), 943−944.
1.2.
1989
Lopp M., Paju A., Kanger T., Välimäe T., Lille Ü. (1989). Synthesis of enynic and dienic Fragments of Leukotrienes and Pheromones. Zhurnal Organicheskoi Khimii, 25 (4), 869−870.

Industrial property
Detailne otsing
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ProgrammLiikNumberNimiProjekti algusProjekti lõppVastutav täitjaAsutusFinantseerijapoolne rahastamine
MUUBF42Balticum Organicum Syntheticum 200601.05.200501.10.2006Margus LoppTallinna Tehnikaülikool; Tallinna Tehnikaülikool, Matemaatika-loodusteaduskond, Keemiainstituut, Orgaanilise keemia õppetool6 391,16 EUR
MUUG4976 (ETF4976)C2-sümmeetrilised heterotsüklilised kiraalsed mõjurid ja katalüsaatorite ligandid: süntees ja rakendused01.01.200231.12.2005Tõnis KangerTallinna Tehnikaülikool; Tallinna Tehnikaülikool, Matemaatika-loodusteaduskond, Keemiainstituut, Orgaanilise keemia õppetool27 865,48 EUR
ETFETF8289Efektiivsus organokatalüüsis 01.01.201031.12.2013Tõnis KangerTallinna Tehnikaülikool, Matemaatika-loodusteaduskond75 773,01 EUR
PUT; PUT_OPPUT1468Halogeenside: kristallidest lahusesse01.01.201731.12.2020Tõnis KangerTallinna Tehnikaülikool, Loodusteaduskond, Keemia ja biotehnoloogia instituut115 200,00 EUR
MUUVA433Hetrogeensete metall katalüsaatorite loomine apatiidi pinnal01.07.200930.06.2014Kaia TõnsuaaduTallinna Tehnikaülikool; Tallinna Tehnikaülikool, Keemia ja materjalitehnoloogia teaduskond, Anorgaaniliste materjalide teaduslaboratoorium0,06 EUR
SFSF0140060s12Katalüütilise asümmeetriline sünteesi ja stereokeemilise analüüsi meetodid ja rakendused 01.01.201231.12.2013Margus LoppTallinna Tehnikaülikool, Matemaatika-loodusteaduskond285 640,00 EUR
TKTAR8103Keemilise bioloogia tippkeskus28.03.200830.11.2015Margus LoppTallinna Tehnikaülikool; Tallinna Tehnikaülikool, Matemaatika-loodusteaduskond, Keemiainstituut, Orgaanilise keemia õppetool198 497,44 EUR
ETFETF6662Kiraalsed diamiinid organokatalüütilistes ja metallkatalüütilistes asümmeetrilistes reaktsioonides01.01.200631.12.2009Tõnis KangerTallinna Tehnikaülikool, Matemaatika-loodusteaduskond37 052,41 EUR
MUUG3164 (ETF3164)Kiraalsed metallikompleksid asümmeetrilises sünteesis01.01.199831.12.2001Tõnis KangerTallinna Tehnikaülikool; Tallinna Tehnikaülikool, Matemaatika-loodusteaduskond, Keemiainstituut, Orgaanilise keemia õppetool3 195,58 EUR
IUTIUT19-32Suunatud asümmeetriline katalüütiline süntees: kompleksne integreeritud käsitlus01.01.201431.12.2019Margus LoppTallinna Tehnikaülikool, Matemaatika-loodusteaduskond; Tallinna Tehnikaülikool, Loodusteaduskond, Keemia ja biotehnoloogia instituut1 040 000,00 EUR
SFSF0351761s01Uued selektiivsed asümmeetrilise sünteesi meetodid ja nende kasutamine bioaktiivsete ühendite saamiseks01.01.200131.12.2005Margus LoppTallinna Tehnikaülikool, Matemaatika-loodusteaduskond345 250,71 EUR
SFSF0142725s06Uued asümmeetrilise sünteesi strateegiad ja meetodid01.01.200631.12.2011Margus LoppTallinna Tehnikaülikool, Matemaatika-loodusteaduskond749 371,30 EUR
MUU590LVähivastased sahhariidide ja nukleosiidide analoogid01.09.200530.06.2009Margus LoppTallinna Tehnikaülikool; Tallinna Tehnikaülikool, Matemaatika-loodusteaduskond, Keemiainstituut, Orgaanilise keemia õppetool88 293,94 EUR