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Tiit Land

https://www.etis.ee/CV/Tiit_Land/eng
25.09.1964
6202003
tiit.land@taltech.ee

Career

Institutions and positions
01.09.2020–...   
Tallinn University of Technology, Rector (1,00)
2011–2020   
Tallinn University, Rector (1,00)
2007–2011   
Tallinn University, Institute of Mathematics and Natural Sciences, Department of Natural Scinces, Professor (1,00)
2006–2007   
Tallinn University, Institute of Mathematics and Natural Sciences, Department of Natural Scinces, Keemia õppetool, Professor (0,50)
01.01.1999–31.12.2006   
researcher/lecturer, Department Neurochemistry and Neurotoxicology, Stockholm Univrersity
01.01.1994–31.12.1999   
researcher, National Institutes of Health (NIH), USA
01.01.1990–31.12.1994   
Ph.D. student, Stockholm University
 
 
Education
1982–1989   
Faculty of Physics and Chemistry, Tartu University, 1989 (cum laude)
 
 
R&D related managerial and administrative work
2008−2011   
Director, Institute of Mathematics and Natural Sciences, Tallinn University
2003−2006   
Director of Studies, Department of Neurochemistry, Stockholm University

Qualifications

Fields of research
ETIS CLASSIFICATION: 4. Natural Sciences and Engineering; 4.16. Biotechnology relating to Natural Sciences and Engineering; SPECIFICATION: 1. Iron regulation, oxidative stress and inflammation 2. Biogenesis of iron-sulfur proteins and their role in iron metabolism 3. Signal transduction mechanisms of novel fragment of amyloid precursor protein (APP) and their in Alzheimer's disease 4. Role of iron in Alzheimer's disease 5. Iron regulation and iron-induced oxidative stress in prion diseases
ETIS CLASSIFICATION: 1. Biosciences and Environment; 1.1. Biochemistry; SPECIFICATION: Neurochemistry
 
 
Additional information
Doctor Philosophy (Ph.D)
Stockholm University, 1994

Supervised dissertations

Publications

Category
Year
Publication
 
1.1.
2017
Kaldmäe, Margit; Zemtsovskaja, Galina; Abina, Jelena; Land, Tiit; Viigimaa, Margus (2017). Prevalence of cardiovascular disease risk factors in Tallinn, Estonia. Medicina, 53 (4), 268−276. DOI: 10.1016/j.medici.2017.07.002.
1.1.
2015
Part, K.; Künnis-Beres, K.; Poska, H.; Land, T.; Shimmo, R.; Zetterström Fernaeus, S. (2015). Amyloid β25–35 induced ROS-burst through NADPH oxidase is sensitive to iron chelation in microglial Bv2 cells. Brain Research, 1629, 282−290. DOI: 10.1016/j.brainres.2015.09.034.
1.1.
2011
Svensson, Christina; Part, Kristin; Künnis-Beres, Kai ; Kaldmäe, Margit; Zetterström Fernaeus, Sandra ; Land, Tiit (2011). Pro-Survival Effects of JNK and p38 MAPK Pathways in LPS-Induced Activation of BV-2 cells. Biochemical and Biophysical Research Communications, 406, 488−492. DOI: 10.1016/j.bbrc.2011.02.083.
1.1.
2010
Martma, Kert; Fernaeus, Sandra; Land, Tiit; Shimmo, Ruth (2010). Study of cell membrane based coatings in capillary electrochromatography. Procedia Chemistry, 2, 26−33.
1.1.
2010
Svensson, Christina; Zetterström Fernaeus, Sandra; Part, Kristin; Reis, Katarina; Land, Tiit (2010). LPS induced iNOS expression in Bv-2 cells is suppressed by an oxidative mechanism acting on the JNK pathway- a potential role for neuroprotection. Brain Research, 1322, 1−7. DOI: 10.1016/j.brainres.2010.01.082.
1.1.
2010
Martma, Kert; Zetterström Fernaeus, Sandra; Land, Tiit; Shimmo, Ruth (2010). New capillary coatings in open tubular CEC as models for biological membranes. Electrophoresis, 31, 1586−1589. DOI: 10.1002/elps.200900587.
3.1.
2009
Land, Tiit (2009). Sequence Analysis and Function Prediction. In: Introduction to Peptides and Proteins (245−256). . Taylor & Francis.
5.1.
2009
Tracy, Linda; Pettersson, Christina; Land, Tiit; Iverfeldt, Kerstin (2009). Signaling pathways regulating C/EBP in glial cells during inflammation. GLIA, 57. Wiley-Liss, S138−S138.
1.1.
2008
Hälldin, Jonas; Land, Tiit (2008). Sulfide increases labile iron pool in RD4 cells. BioMetals, 21, 127−131. DOI: 10.1007/s10534-007-9099-2.
5.1.
2008
Pettersson, Christina; Reis, Katarina; Zetterstrom Fernaeus, Sandra; Land, Tiit (2008). NAC and DFO enhance LPS induced INOS expression in BV-2 cells through a p38 MAPK dependent mechanism. JOURNAL OF NEUROCHEMISTRY, 104: 39th Annual Meeting of the American-Society-for-Neurochemistry San Antonio, TX, MAR 01-05, 2008 Amer Soc Neurochem. Blackwell Publishing, 106−107.
1.1.
2007
Reis, K.; Zharkovsky, A.; Bogdanovic, N.; Karelson, E.; Land, T. (2007). Critical role of methionine-722 in the stimulation of human brain G-proteins and neurotoxicity induced by London familial Alzheimer's disease (FAD) mutated V717G-APP(714-723). Neuroscience, 144 (2), 571−578.
3.1.
2007
Karelson, E.; Eriksson, J.; Bogdanovic, N.; Jefremov, V.; Land, T. (2007). Oxidative-dependent stimulation of G-proteins in human control and Alzheimer's disease brain by V717G ("London") FAD mutant of APP714-723. New Trends in Alzheimer and Parkinson disease. Proceedings of 8th International Conference on Alzheimer's and Parkinson's Diseases. Bologna: Medimond, 99−103.
5.2.
2007
Karelson, E.; Land, T.; Bogdanovic, N. (2007). Oxidative-dependent stimulation of G-proteins in human control and Alzheimer's disease brain by V717G (London) FAD mutant of APP714-723. Neurodegenerative Diseases, 4(suppl1) : 8th International Conference AD/PD; Salzburg, Austria; March 14-18, 2007. S. Karger Medical and Scientific Publishers, 61.
1.1.
2006
Reis, Katarina; Hälldin, Jonas; Fernaeus, Sandra; Pettersson, Christina; Land, Tiit (2006). NADPH oxidase inhibitor diphenyliodonium abolishes LPS induced down-regulation of transferrin receptor expression in N2a and BV-2 cells. Journal of Neuroscience Research, 84 (5), 1047−1052.
1.1.
2005
Fernaeus, S.; Reis, K.; Bedecs, K.; Land, T. (2005). Increased susceptibility to oxidative stress in scrapie-infected cells is associated with intracellular iron status. Neuroscience Letters, 389 (3), 133−136.
1.1.
2005
Fernaeus, S.; Halldin, J.; Bedecs, K.; Land, T. (2005). Changed iron regulation in scrapie-infected neuroblastoma cells. Molecular Brain Research, 133 (2), 266−273.
1.1.
2005
Fernaeus, S.; Land, T. (2005). Increased iron-induced oxidative stress and toxicity in scrapie-infected neuroblastoma cells. Neuroscience Letters, 382 (3), 217−220.
1.1.
2005
Karelson, E.; Fernaeus, S.; Reis, K.; Bogdanovic, N.; Land, T. (2005). Stimulation of G-proteins in human control and Alzheimer's disease brain by FAD mutants of APP(714-723): implication of oxidative mechanisms. Journal of Neuroscience Research, 79 (3), 368−374.
1.1.
2004
Kilk, K.; Elmquist, A.; Saar, K.; Pooga, M.; Land, T.; Bartfai, T.; Soomets, U.; Langel, U. (2004). Targeting of antisense PNA oligomers to human galanin receptor type 1 mRNA. Neuropeptides, 38 (5), 316−324.
1.1.
2003
Mahlapuu, R.; Viht, K.; Balaspiri, L.; Bogdanovic, N.; Saar, K.; Soomets, U.; Land, T.; Zilmer, M.; Karelson, E.; Langel, U. (2003). Amyloid precursor protein carboxy-terminal fragments modulate G-proteins and adenylate cyclase activity in Alzheimer's disease brain. Molecular Brain Research, 117 (1), 73−82.
1.1.
2001
Rezaei, K.; Xu, IS.; Wu, WP.; Shi, TJ.; Soomets, U.; Land, T.; Xu, XJ.; Wiesenfeld-Hallin, Z.; Hokfelt, T.; Bartfai, T.; Langel, U. (2001). Intrathecal administration of PNA targeting galanin receptor reduces galanin-mediated inhibitory effect in the rat spinal cord. Neuroreport, 12 (2), 317−320.
1.1.
2001
Pooga, M.; Land, T.; Bartfai, T.; Langel, U. (2001). PNA oligomers as tools for specific modulation of gene expression. Biomolecular Engineering, 17 (6), 183−192.
1.1.
1998
Land, Tiit; Rouault, T. (1998). Targeting of a human iron-sulfur cluster assembly enzyme, nifs, to different subcellular compartments is regulated through alternative AUG utilization. Molecular Cell, 2, 807−815.
1.1.
1995
Lundkvist, J.; Land, T.; Kahl, U.; Bedecs, K.; Bartfai, T (1995). cDNA sequence, ligand binding, and regulation of galanin/GMAP in mouse brain. Neuroscience Letters, 200 (2), 121−124.
1.1.
1993
Gregersen, S.; Lindskog, S.; Land, T.; Langel, U.; Bartfai, T.; Ahren, B. (1993). Blockade of galanin-induced inhibition of insulin secretion from isolated mouse islets by the nonmethionine containing antagonist M35. European Journal of Pharmacology, 232 (1), 35−39.
1.1.
1993
Girotti, P.; Bertorelli, R.; Fisone, G.; Land, T.; Langel, U.; Consolo, S.; Bartfai, T. (1993). N-terminal galanin fragments inhibit the hippocampal release of acetylcholine in vivo. Brain Research, 612, 258−262.
1.1.
1993
Arvidsson, K.; Land, T.; Langel, U.; Bartfai, T.; Ehrenberg, A. (1993). Solution structure by 2D 1H-NMR of a chimeric peptide recognized by galanin and neuropeptide Y receptors. Biochemistry, 32 (30), 7787−7798.
1.1.
1993
Pramanik, A.; Ogren, S.O.; Land, T.; Langel, U. (1993). Galanin antagonists M15 and M35 - differentisl-effects on acetylcholine-release in the rat striatum. Neuropsychopharmacology, 9, S81−S81.
1.1.
1993
Ogren, S.O.; Pramanik, A.; Land, T.; Langel, U. (1993). Differential effects of the putative galanin receptor antagonists M15 and M35 on striatal acetylcholine release. European Journal of Pharmacology, 242 (1), 59−64.
1.1.
1993
Hulting, A.L.; Land, T.; Berthold, N.; Langel, U.; Hokfelt, T.; Bartfai, T. (1993). Galanin receptors from human pituitary-tumors assayed with human galanin as ligand. Brain Research, 625, 173−176.
1.1.
1992
Lindskog, S.; Ahren, B.; Land, T.; Langel, U.; Bartfai, T. (1992). The novel high-affinity antagonist, galantide, blocks the galanin-mediated inhibition of glucose-induced insulin secretion. European Journal of Pharmacology, 210 (2), 183−188.
1.1.
1992
Langel, U.; Land, T.; Bartfai, T. (1992). Design of chimeric peptide ligands to galanin receptors and substance-P receptors. International journal of peptide & protein research, 39, 516−522.
1.1.
1992
Gregersen, S.; Ahren, B.; Lindskog, S.; Land, T.; Langel, U.; Bartfai, T. (1992). Galantide-II is a stable galanin antagonist. Diabetologia, 35, A126.
1.1.
1991
Land, T.; Langel, U.; Bartfai, T. (1991). Hypothalamic degradation of galanin(1–29) and galanin(1–16): identification and characterization of the peptidolytic products. Brain Research, 558 (2), 245−250.
1.1.
1991
Land, T.; Langel, U.; Low, M.; Berthold, M.; Unden, A.; Bartfai, T. (1991). Linear and cyclic N-terminal galanin fragments and analogs as ligands at the hypothalamic galanin receptor. International journal of peptide & protein research, 38 (3), 262−272.
1.1.
1991
Bartfai, T.; Bedecs, K.; Land, T.; Langel, U.; Bertorelli, R.; Girotti, P.; Consolo, S.; Xu, X.J.; Wiesenfeld-Hallin, Z.; Nilsson, S.; Pieribone, V.A.; Hokfelt, T. (1991). M-15: High-affinity chimeric peptide that blocks the neuronal actions of galanin in the hippocampus, locus coeruleus, and spinal cord. Proceedings of the National Academy of Sciences, 88, 10961−10965.
3.1.
1991
Fisone, G.; Langel, Ü.; Land, T.; Berthold, M.; Bertorelli, R.; Girotti, P.; Consolo, S.; Crowley, JN.; Hökfelt, T.; Bartfai, T. (1991). Galanin receptor ligands in the hippocampus: galanin, N-terminal galanin fragments and analogues. In: Hokfelt, T.; Bartfai, T.; Jacobowitz, D.; Ottoson, D. (Ed.). Galanin: A new multifunctional peptide in the neuro-endocrine system (213−220). . New York: Macmillan Press. (Wenner-Gren International Symposium Series).
3.1.
1991
Land, T.; Langel, Ü.; Fisone, G.; Bedecs, K.; Bartfai, T. (1991). Assay for galanin receptor. In: Methods in Neurosciences (225−234). . Academic Press.
5.1.
1990
Langel, Ü.; Land, T.; Bartfai, T. (1990). Synthetic galanin analogs with biochemical activity. Peptides: Twenty-First European peptide Symposium; September 2-8, 1990; Platja d´Aro, Spain. Ed. Giralt, E.; Andreu, D., 727−728.
22.06.2021

Tiit Land

https://www.etis.ee/CV/Tiit_Land/est
25.09.1964
6202003
tiit.land@taltech.ee

Teenistuskäik

Töökohad ja ametid
01.09.2020–...   
Tallinna Tehnikaülikool, Rektor (1,00)
2011–2020   
Tallinna Ülikool, Rektor (1,00)
2007–2011   
Tallinna Ülikool, Matemaatika ja Loodusteaduste Instituut, Loodusteaduste osakond, Professor (1,00)
2006–2007   
Tallinna Ülikool, Matemaatika ja Loodusteaduste Instituut, Loodusteaduste osakond, Keemia õppetool, Professor (0,50)
01.01.1999–31.12.2006   
teadur ja õppejõud; Stockholmi Ülikooli Neurokeemia ja Neurotoksikoloogia Instituut
01.01.1994–31.12.1999   
teadur, USA Rahvuslikud Tervise Instituudid (National Institutes of Health, NIH)
01.01.1990–31.12.1994   
doktorant, Stockholmi Ülikool
 
 
Haridustee
1982–1989   
Tartu Ülikooli Füüsika-keemia teaduskond, 1989 (cum laude)
 
 
Teadusorganisatsiooniline ja -administratiivne tegevus
2008−2011   
Direktor, Tallinna Ülikool, Matemaatika ja Loodusteaduste Instituut
2003−2006   
Õppeprodekaan, Stockholmi Ülikool, Neurokeemia Instituut

Kvalifikatsioon

Teadustöö põhisuunad
ETIS KLASSIFIKAATOR: 4. Loodusteadused ja tehnika; 4.16. Biotehnoloogia (loodusteadused ja tehnika); TÄPSUSTUS: 1. Raua regulatsioon, oksüdatiivne stress ja põletikulised protsessid 2. Raud-väävel seoseliste valkude biogenees ja roll raua ainevahetuses 3. Beeta-amüloid prekursor valkude (APP) uute fragmentide signaali ülekande mehhanismid ja nende roll Alzheimeri tõves 4. Raua roll Alzheimeri tõves 5. Raua regulatsioon ja raua poolt indutseeritud oksüdatiivne stress prioonhaigustes
ETIS KLASSIFIKAATOR: 1. Bio- ja keskkonnateadused; 1.1. Biokeemia; TÄPSUSTUS: Neurokeemia
 
 
Lisainfo
filosoofiadoktor (Ph.D)
Stockholmi Ülikool, 1994

Juhendatud väitekirjad

Publikatsioonid

Klass
Aasta
Publikatsioon
 
1.1.
2017
Kaldmäe, Margit; Zemtsovskaja, Galina; Abina, Jelena; Land, Tiit; Viigimaa, Margus (2017). Prevalence of cardiovascular disease risk factors in Tallinn, Estonia. Medicina, 53 (4), 268−276. DOI: 10.1016/j.medici.2017.07.002.
1.1.
2015
Part, K.; Künnis-Beres, K.; Poska, H.; Land, T.; Shimmo, R.; Zetterström Fernaeus, S. (2015). Amyloid β25–35 induced ROS-burst through NADPH oxidase is sensitive to iron chelation in microglial Bv2 cells. Brain Research, 1629, 282−290. DOI: 10.1016/j.brainres.2015.09.034.
1.1.
2011
Svensson, Christina; Part, Kristin; Künnis-Beres, Kai ; Kaldmäe, Margit; Zetterström Fernaeus, Sandra ; Land, Tiit (2011). Pro-Survival Effects of JNK and p38 MAPK Pathways in LPS-Induced Activation of BV-2 cells. Biochemical and Biophysical Research Communications, 406, 488−492. DOI: 10.1016/j.bbrc.2011.02.083.
1.1.
2010
Martma, Kert; Fernaeus, Sandra; Land, Tiit; Shimmo, Ruth (2010). Study of cell membrane based coatings in capillary electrochromatography. Procedia Chemistry, 2, 26−33.
1.1.
2010
Svensson, Christina; Zetterström Fernaeus, Sandra; Part, Kristin; Reis, Katarina; Land, Tiit (2010). LPS induced iNOS expression in Bv-2 cells is suppressed by an oxidative mechanism acting on the JNK pathway- a potential role for neuroprotection. Brain Research, 1322, 1−7. DOI: 10.1016/j.brainres.2010.01.082.
1.1.
2010
Martma, Kert; Zetterström Fernaeus, Sandra; Land, Tiit; Shimmo, Ruth (2010). New capillary coatings in open tubular CEC as models for biological membranes. Electrophoresis, 31, 1586−1589. DOI: 10.1002/elps.200900587.
3.1.
2009
Land, Tiit (2009). Sequence Analysis and Function Prediction. In: Introduction to Peptides and Proteins (245−256). . Taylor & Francis.
5.1.
2009
Tracy, Linda; Pettersson, Christina; Land, Tiit; Iverfeldt, Kerstin (2009). Signaling pathways regulating C/EBP in glial cells during inflammation. GLIA, 57. Wiley-Liss, S138−S138.
1.1.
2008
Hälldin, Jonas; Land, Tiit (2008). Sulfide increases labile iron pool in RD4 cells. BioMetals, 21, 127−131. DOI: 10.1007/s10534-007-9099-2.
5.1.
2008
Pettersson, Christina; Reis, Katarina; Zetterstrom Fernaeus, Sandra; Land, Tiit (2008). NAC and DFO enhance LPS induced INOS expression in BV-2 cells through a p38 MAPK dependent mechanism. JOURNAL OF NEUROCHEMISTRY, 104: 39th Annual Meeting of the American-Society-for-Neurochemistry San Antonio, TX, MAR 01-05, 2008 Amer Soc Neurochem. Blackwell Publishing, 106−107.
1.1.
2007
Reis, K.; Zharkovsky, A.; Bogdanovic, N.; Karelson, E.; Land, T. (2007). Critical role of methionine-722 in the stimulation of human brain G-proteins and neurotoxicity induced by London familial Alzheimer's disease (FAD) mutated V717G-APP(714-723). Neuroscience, 144 (2), 571−578.
3.1.
2007
Karelson, E.; Eriksson, J.; Bogdanovic, N.; Jefremov, V.; Land, T. (2007). Oxidative-dependent stimulation of G-proteins in human control and Alzheimer's disease brain by V717G ("London") FAD mutant of APP714-723. New Trends in Alzheimer and Parkinson disease. Proceedings of 8th International Conference on Alzheimer's and Parkinson's Diseases. Bologna: Medimond, 99−103.
5.2.
2007
Karelson, E.; Land, T.; Bogdanovic, N. (2007). Oxidative-dependent stimulation of G-proteins in human control and Alzheimer's disease brain by V717G (London) FAD mutant of APP714-723. Neurodegenerative Diseases, 4(suppl1) : 8th International Conference AD/PD; Salzburg, Austria; March 14-18, 2007. S. Karger Medical and Scientific Publishers, 61.
1.1.
2006
Reis, Katarina; Hälldin, Jonas; Fernaeus, Sandra; Pettersson, Christina; Land, Tiit (2006). NADPH oxidase inhibitor diphenyliodonium abolishes LPS induced down-regulation of transferrin receptor expression in N2a and BV-2 cells. Journal of Neuroscience Research, 84 (5), 1047−1052.
1.1.
2005
Fernaeus, S.; Reis, K.; Bedecs, K.; Land, T. (2005). Increased susceptibility to oxidative stress in scrapie-infected cells is associated with intracellular iron status. Neuroscience Letters, 389 (3), 133−136.
1.1.
2005
Fernaeus, S.; Halldin, J.; Bedecs, K.; Land, T. (2005). Changed iron regulation in scrapie-infected neuroblastoma cells. Molecular Brain Research, 133 (2), 266−273.
1.1.
2005
Fernaeus, S.; Land, T. (2005). Increased iron-induced oxidative stress and toxicity in scrapie-infected neuroblastoma cells. Neuroscience Letters, 382 (3), 217−220.
1.1.
2005
Karelson, E.; Fernaeus, S.; Reis, K.; Bogdanovic, N.; Land, T. (2005). Stimulation of G-proteins in human control and Alzheimer's disease brain by FAD mutants of APP(714-723): implication of oxidative mechanisms. Journal of Neuroscience Research, 79 (3), 368−374.
1.1.
2004
Kilk, K.; Elmquist, A.; Saar, K.; Pooga, M.; Land, T.; Bartfai, T.; Soomets, U.; Langel, U. (2004). Targeting of antisense PNA oligomers to human galanin receptor type 1 mRNA. Neuropeptides, 38 (5), 316−324.
1.1.
2003
Mahlapuu, R.; Viht, K.; Balaspiri, L.; Bogdanovic, N.; Saar, K.; Soomets, U.; Land, T.; Zilmer, M.; Karelson, E.; Langel, U. (2003). Amyloid precursor protein carboxy-terminal fragments modulate G-proteins and adenylate cyclase activity in Alzheimer's disease brain. Molecular Brain Research, 117 (1), 73−82.
1.1.
2001
Rezaei, K.; Xu, IS.; Wu, WP.; Shi, TJ.; Soomets, U.; Land, T.; Xu, XJ.; Wiesenfeld-Hallin, Z.; Hokfelt, T.; Bartfai, T.; Langel, U. (2001). Intrathecal administration of PNA targeting galanin receptor reduces galanin-mediated inhibitory effect in the rat spinal cord. Neuroreport, 12 (2), 317−320.
1.1.
2001
Pooga, M.; Land, T.; Bartfai, T.; Langel, U. (2001). PNA oligomers as tools for specific modulation of gene expression. Biomolecular Engineering, 17 (6), 183−192.
1.1.
1998
Land, Tiit; Rouault, T. (1998). Targeting of a human iron-sulfur cluster assembly enzyme, nifs, to different subcellular compartments is regulated through alternative AUG utilization. Molecular Cell, 2, 807−815.
1.1.
1995
Lundkvist, J.; Land, T.; Kahl, U.; Bedecs, K.; Bartfai, T (1995). cDNA sequence, ligand binding, and regulation of galanin/GMAP in mouse brain. Neuroscience Letters, 200 (2), 121−124.
1.1.
1993
Gregersen, S.; Lindskog, S.; Land, T.; Langel, U.; Bartfai, T.; Ahren, B. (1993). Blockade of galanin-induced inhibition of insulin secretion from isolated mouse islets by the nonmethionine containing antagonist M35. European Journal of Pharmacology, 232 (1), 35−39.
1.1.
1993
Girotti, P.; Bertorelli, R.; Fisone, G.; Land, T.; Langel, U.; Consolo, S.; Bartfai, T. (1993). N-terminal galanin fragments inhibit the hippocampal release of acetylcholine in vivo. Brain Research, 612, 258−262.
1.1.
1993
Arvidsson, K.; Land, T.; Langel, U.; Bartfai, T.; Ehrenberg, A. (1993). Solution structure by 2D 1H-NMR of a chimeric peptide recognized by galanin and neuropeptide Y receptors. Biochemistry, 32 (30), 7787−7798.
1.1.
1993
Pramanik, A.; Ogren, S.O.; Land, T.; Langel, U. (1993). Galanin antagonists M15 and M35 - differentisl-effects on acetylcholine-release in the rat striatum. Neuropsychopharmacology, 9, S81−S81.
1.1.
1993
Ogren, S.O.; Pramanik, A.; Land, T.; Langel, U. (1993). Differential effects of the putative galanin receptor antagonists M15 and M35 on striatal acetylcholine release. European Journal of Pharmacology, 242 (1), 59−64.
1.1.
1993
Hulting, A.L.; Land, T.; Berthold, N.; Langel, U.; Hokfelt, T.; Bartfai, T. (1993). Galanin receptors from human pituitary-tumors assayed with human galanin as ligand. Brain Research, 625, 173−176.
1.1.
1992
Lindskog, S.; Ahren, B.; Land, T.; Langel, U.; Bartfai, T. (1992). The novel high-affinity antagonist, galantide, blocks the galanin-mediated inhibition of glucose-induced insulin secretion. European Journal of Pharmacology, 210 (2), 183−188.
1.1.
1992
Langel, U.; Land, T.; Bartfai, T. (1992). Design of chimeric peptide ligands to galanin receptors and substance-P receptors. International journal of peptide & protein research, 39, 516−522.
1.1.
1992
Gregersen, S.; Ahren, B.; Lindskog, S.; Land, T.; Langel, U.; Bartfai, T. (1992). Galantide-II is a stable galanin antagonist. Diabetologia, 35, A126.
1.1.
1991
Land, T.; Langel, U.; Bartfai, T. (1991). Hypothalamic degradation of galanin(1–29) and galanin(1–16): identification and characterization of the peptidolytic products. Brain Research, 558 (2), 245−250.
1.1.
1991
Land, T.; Langel, U.; Low, M.; Berthold, M.; Unden, A.; Bartfai, T. (1991). Linear and cyclic N-terminal galanin fragments and analogs as ligands at the hypothalamic galanin receptor. International journal of peptide & protein research, 38 (3), 262−272.
1.1.
1991
Bartfai, T.; Bedecs, K.; Land, T.; Langel, U.; Bertorelli, R.; Girotti, P.; Consolo, S.; Xu, X.J.; Wiesenfeld-Hallin, Z.; Nilsson, S.; Pieribone, V.A.; Hokfelt, T. (1991). M-15: High-affinity chimeric peptide that blocks the neuronal actions of galanin in the hippocampus, locus coeruleus, and spinal cord. Proceedings of the National Academy of Sciences, 88, 10961−10965.
3.1.
1991
Fisone, G.; Langel, Ü.; Land, T.; Berthold, M.; Bertorelli, R.; Girotti, P.; Consolo, S.; Crowley, JN.; Hökfelt, T.; Bartfai, T. (1991). Galanin receptor ligands in the hippocampus: galanin, N-terminal galanin fragments and analogues. In: Hokfelt, T.; Bartfai, T.; Jacobowitz, D.; Ottoson, D. (Ed.). Galanin: A new multifunctional peptide in the neuro-endocrine system (213−220). . New York: Macmillan Press. (Wenner-Gren International Symposium Series).
3.1.
1991
Land, T.; Langel, Ü.; Fisone, G.; Bedecs, K.; Bartfai, T. (1991). Assay for galanin receptor. In: Methods in Neurosciences (225−234). . Academic Press.
5.1.
1990
Langel, Ü.; Land, T.; Bartfai, T. (1990). Synthetic galanin analogs with biochemical activity. Peptides: Twenty-First European peptide Symposium; September 2-8, 1990; Platja d´Aro, Spain. Ed. Giralt, E.; Andreu, D., 727−728.
22.06.2021

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ProgramTypeNumberNameProject startProject endPrincipal investigatorInstitutionFinancing
MUUF/1312 (TLÜ senati teaduskomisjoni istungi protokoll nr 15 23.04.2012 )Preparatory allowence for Institutional Research Funding theme "Stochastic nano- ja mesosystems in analytical biochemistry"23.04.201231.12.2012Tiit LandTallinn University, Institute of Mathematics and Natural Sciences10 000,00 EUR
ETFETF6574Mitochondrial-aconitase dysfunction in aging and degenerative brain: mechanisms and therapeutic possibilities01.01.200631.12.2009Ceslava KairaneUniversity of Tartu; University of Tartu, Faculty of Medicine34 493,12 EUR
MUUAU, 20207 (TLÜ teadusprorektori käskkiri nr. 58, 15.05.2007)Iron regulation, oxidative stress and inflammation: relationships and mechanisms01.05.200731.12.2007Tiit LandTallinn University; Tallinn University, Institute of Mathematics and Natural Sciences, Department of Natural Scinces31 955,82 EUR
ETFETF7333Studies of the relationships between iron regulation, oxidative mechanisms and inflammation01.01.200831.12.2011Tiit LandTallinn University, Institute of Mathematics and Natural Sciences86 296,05 EUR
SFSF0130171s08Iron regulation, oxidative stress and inflammation: mechanisms, relationships and their role in neurodegeneration01.01.200831.12.2012Tiit LandTallinn University, Institute of Mathematics and Natural Sciences272 200,43 EUR
MJDMJD7Studies of the neurotoxic mechanisms of mutated versions of APP related to Familial Alzheimer’s Disease01.08.200931.07.2012Sandra Zetterström FernaeusTallinn University; Tallinn University, Institute of Mathematics and Natural Sciences83 843,26 EUR
MUUAU30908 (TLÜ teadusprorektori korraldus nr. 39, 27.05.2008)The activation of center of excellence "Studies of natural and man-made environments"01.09.200830.05.2009Jaan-Mati PunningTallinn University; Tallinn University, Institute of History; Tallinn University, Institute of Ecology; Tallinn University, Institute of Mathematics and Natural Sciences31 955,82 EUR
MUUTF1515 (TLÜ senati teaduskomisjoni istungi protokoll 20.04.2015 nr 9)TU Center of Excellence in Behavioral and Neuroscience 01.05.201531.12.2023Ruth ShimmoTallinn University, Institute of Mathematics and Natural Sciences138 000,00 EUR
MUUAU7109 (TLÜ senati teaduskomisjoni otsus 26.10.09, TLÜ teaduskomisjoni otsus 06.10.2010)TU natural sciences center of excellence "Natural and Built Environment Studies" doctoral study support project01.09.200928.02.2011Tiit LandTallinn University, Institute of History; Tallinn University, Institute of Ecology; Tallinn University, Institute of Mathematics and Natural Sciences31 955,82 EUR
MUUAU/9811 (TLÜ senati teaduskomisjoni istungi protokoll 10. oktoober 2011 nr 11 )TU natural sciences center of excellence "Natural and Built Environment Studies" doctoral study support project01.09.201131.08.2014Ruth ShimmoTallinn University, Institute of Mathematics and Natural Sciences64 000,00 EUR