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Olen nõus

Tiit Lukk

https://www.etis.ee/CV/Tiit_Lukk/est
29.04.1981
56776321
tiit.lukk@ttu.ee

Teenistuskäik

Töökohad ja ametid
01.09.2017–...   
Tallinna Tehnikaülikool, Loodusteaduskond, Keemia ja biotehnoloogia instituut, sihtrahastusega vanemteadur (1,00)
01.01.2017–30.08.2017   
Tallinna Tehnikaülikool, Loodusteaduskond, Keemia ja biotehnoloogia instituut, Teadur (1,00)
15.11.2016–31.12.2016   
Tallinna Tehnikaülikool, Loodusteaduskond, Keemia ja biotehnoloogia instituut, spetsialist (1,00)
2013–31.10.2016   
Macromolecular Diffraction facility at the Cornell High Energy Synchrotron Source, Teadur (1,00)
2009–2013   
University of Illinois at Urbana-Champaign, Järeldoktor (1,00)
2003–2004   
Eesti Biokeskus, Vanemlaborant (1,00)
 
 
Haridustee
2004–2009   
Illinoisi Ülikool Urbana-Champaign'is, biokeemia kraadiõpe, Prof. John Gerlt'i laboris, PhD 2009
1999–2003   
Tartu Ülikool, bakalaureuseõpe, bioloogia-geograafia teaduskond, biotehnoloogia ja biomeditsiini erialal
 
 
Teadusorganisatsiooniline ja -administratiivne tegevus
2022−...   
Ameerika Keemia Selts, liige
2021−...   
Teadusajakirja Energies külalistoimetaja
2020−...   
Eesti teadusagentuuri loodusteaduste ekspertkomisjoni liige
2020−...   
Euroopa Biotehnoloogia Föderatsiooni liige
2019−...   
Eesti Biokeemia Selts, president
2018−...   
Eesti Biokeemia Selts, juhatuse liige
2018−...   
Eesti Esindaja Euroopa Biokeemia Seltside Föderatsiooni juures
2018−...   
CA17128 LignoCOST - Euroopaülese ligniini jätkusuutliku väärindamisevõrgustiku loomine, korralduskomitee liige
2017−...   
TTÜ Keemia- ja biotehnoloogia instituudi MSc kaitsmiskomisjoni liige
2017−...   
TTÜ Keemia- ja biotehnoloogia instituudi PhD kaitsmiskomisjoni liige, eelretsenseerija
2022−2022   
FEBS3+ konverentsi peakorraldaja Tallinnas 2022 Juunis
2019−2019   
Eesti Biokeemia Selts 60 - teaduskonverentsi korraldaja
2015−2015   
Töötoa "Fast framing detectors and their applications in time-resolved crystallography/BioSAXS" organiseerija Cornelli Ülikoolis

Kvalifikatsioon

Teaduskraadid
Tiit Lukk, doktorikraad, 2009, (juh) John A. Gerlt, Discovery of Function in the Enolase Superfamily (Ensüümi funktsiooni avastamine enolaasi superperekonnas), University of Illinois at Urbana-Champaign
 
 
Teadustöö põhisuunad
ETIS KLASSIFIKAATOR: 4. Loodusteadused ja tehnika; 4.12. Protsessitehnoloogia ja materjaliteadus; CERCS KLASSIFIKAATOR: T460 Puidu-, tselluloosi- ja paberitehnoloogia
ETIS KLASSIFIKAATOR: 4. Loodusteadused ja tehnika; 4.16. Biotehnoloogia (loodusteadused ja tehnika); CERCS KLASSIFIKAATOR: T360 Biokeemiatehnoloogia
ETIS KLASSIFIKAATOR: 1. Bio- ja keskkonnateadused; 1.1. Biokeemia; CERCS KLASSIFIKAATOR: P310 Proteiinid, ensümoloogia

Jooksvad projektid

Juhendamisel väitekirjad

Juhendatud väitekirjad

Juhendatud järeldoktorid

  • 01.01.2020−01.09.2021 Zeba Usmani "Investigation of the role of actinobacteria in bioremediation processes and evolution of soil chemistry" Tallinna Tehnikaülikool

Publikatsioonid

Klass
Aasta
Publikatsioon
 
1.1.
2022
Usmani, Z.; Sharma, M.; Lukk, T.; Karpichev, Y.; Thakur, V. K.; Kumar, V.; Allaoui, A.; Awasthi, A. K.; Gupta, V. K. (2022). Developments in enzyme and microalgae based biotechniques to remediate micropollutants from aqueous systems—A review. Critical Reviews in Environmental Science and Technology, 52 (10), 1684−1729. DOI: 10.1080/10643389.2020.1862551.
1.1.
2022
Zovo, K.; Pupart, H.; Van Wieren, A.; Gillilan, R. E.; Huang, Q.; Majumdar, S.; Lukk, T. (2022). Substitution of the Methionine Axial Ligand of the T1 Copper for the Fungal-like Phenylalanine Ligand (M298F) Causes Local Structural Perturbations that Lead to Thermal Instability and Reduced Catalytic Efficiency of the Small Laccase from Streptomyces coelicolor A3(2). ACS Omega, 7 (7), 6184−6194. DOI: 10.1021/acsomega.1c06668.
1.1.
2022
Cronan, J. E.; Lukk, T. (2022). Advances in the Structural Biology, Mechanism and Physiology of Cyclopropane Fatty Acid Modification of Bacterial Membranes. Microbiology and Molecular Biology Reviews : Mmbr. DOI: 10.1128/mmbr.00013-22.
1.1.
2022
Jõul, P.; Ho, T. T.; Kallavus, U.; Konist, A.; Leiman, K.; Salm, O.-S.; Kulp, M.; Koel, M.; Lukk, T.; (2022). Characterization of Organosolv Lignins and Their Application in the Preparation of Aerogels. Materials, 15 (8), #2861. DOI: 10.3390/ma15082861.
5.2.
2022
Mohan, M.; Duvanova, E.; Lukk, T.; Karpichev, Y. (2022). Synthesis and antibacterial properties of lignin-based amino and quaternary ammonium surfactants. 5th International Symposium on Nanoparticles, Nanomaterials, and Applications 2002 (ISN2A 2022); Portugal, 24-27 January 2022. Ed. C. Lodeiro. Caparica-Portugal: PROTEOMASS Scientific Society (Portugal), 208.
1.1.
2021
Usmani, Zeba; Sharma, Minaxi; Awasthi, Abhishek Kumar; Sivakumar, Nallusamy; Lukk, Tiit; Pecoraro, Lorenzo; Thakur, Vijay Kumar; Roberts, Dave; Newbold, John; Gupta, Vijai Kumar (2021). Bioprocessing of waste biomass for sustainable product development and minimizing environmental impact. Bioresource Technology, 322, ARTN 124548. DOI: 10.1016/j.biortech.2020.124548.
1.1.
2021
Usmani, Z.; Kulp, M.; Lukk, T. (2021). Bioremediation of lindane contaminated soil: Exploring the potential of Actinobacterial strains. Chemosphere, 278, #130468. DOI: 10.1016/j.chemosphere.2021.130468.
1.1.
2021
Usmani, Z.; Sharma, M.; Awasthi, A. K.; Lukk, T.; Tuohy, M. G.; Gong, L.; Nguyen-Tri, P.; Goddard, A. D.; Bill, R. M.; Nayak, S. C.; Gupta, V. K. (2021). Lignocellulosic biorefineries: The current state of challenges and strategies for efficient commercialization. Renewable and Sustainable Energy Reviews, 148, #111258. DOI: 10.1016/j.rser.2021.111258.
1.1.
2021
Fujinami, D.; Garcia de Gonzalo, C. V.; Biswas, S.; Hao, Y.; Wang, H.; Garg, N.; Lukk, T.; Nair, S. K.; van der Donk, W. A. (2021). Structural and mechanistic investigations of protein S-glycosyltransferases. Cell Chemical Biology. DOI: 10.1016/j.chembiol.2021.06.009.
1.1.
2021
Usmani, Z.; Lukk, T.; Mohanachandran, D. K.; Thakur, V. K.; Gupta, V. K.; Robert, D.; Raj, J.; Scarpa, F.; Gupta, R. K. (2021). Biosafe sustainable antimicrobial encapsulation and coatings for targeted treatment and infections prevention: Preparation for another pandemic. Current Research in Green and Sustainable Chemistry, 4, #100074. DOI: 10.1016/j.crgsc.2021.100074.
1.1.
2019
Ernits, Karin; Eek, Priit; Lukk, Tiit; Visnapuu, Triinu; Alamäe, Tiina (2019). First crystal structure of an endo-levanase – the BT1760 from a human gut commensal Bacteroides thetaiotaomicron. Scientific Reports, 9 (1), 8443. DOI: 10.1038/s41598-019-44785-0.
5.2.
2019
Ernits, K.; Eek, P.; Lukk, T.; Visnapuu, T., Alamäe, T. (2019). First crystal structure of a bacterial endo-levanase. In: (22−22). FEBS+ conference of Latvian, Lithuanian and Estonian Biochemical Societies. 17-19 June 2019. Riga, Latvia: University of Latvia.
1.1.
2016
Lukk, Tiit; Gillilan, Richard E; Szebenyi, Doletha M E; Zipfel, Warren R (2016). A visible-light-excited fluorescence method for imaging protein crystals without added dyes. Journal of Applied Crystallography, 49 (Pt 1), 234−240.
1.1.
2015
Garg, Aprajita; Lukk, Tiit; Kumar, Vidya; Choi, Jae-Yeon; Augagneur, Yoann; Voelker, Dennis R; Nair, Satish; Ben Mamoun, Choukri (2015). Structure, function and inhibition of the phosphoethanolamine methyltransferases of the human malaria parasites Plasmodium vivax and Plasmodium knowlesi. Scientific Reports, 5, 9064−9064. DOI: 10.1038/srep09064.
1.1.
2015
Dong, Shi-Hui; Tang, Weixin; Lukk, Tiit; Yu, Yi; Nair, Satish K; van der Donk, Wilfred A (2015). The enterococcal cytolysin synthetase has an unanticipated lipid kinase fold. eLife, 4, 1−18. DOI: 10.7554/eLife.07607.
1.1.
2015
Organtini, Lindsey J; Allison, Andrew B; Lukk, Tiit; Parrish, Colin R; Hafenstein, Susan (2015). Global displacement of canine parvovirus by a host-adapted variant: structural comparison between pandemic viruses with distinct host ranges. Journal of Virology, 89 (3), 1909−1912. DOI: 10.1128/JVI.02611-14.
1.1.
2014
Wichelecki, Daniel J; Balthazor, Bryan M; Chau, Anthony C; Vetting, Matthew W; Fedorov, Alexander A; Fedorov, Elena V; Lukk, Tiit; Patskovsky, Yury V; Stead, Mark B; Hillerich, Brandan S; Seidel, Ronald D; Almo, Steven C; Gerlt, John A (2014). Discovery of function in the enolase superfamily: D-mannonate and d-gluconate dehydratases in the D-mannonate dehydratase subgroup. Biochemistry, 53 (16), 2722−2731. DOI: 10.1021/bi500264p.
1.1.
2014
Majumdar, Sudipta; Lukk, Tiit; Solbiati, Jose O; Bauer, Stefan; Nair, Satish K; Cronan, John E; Gerlt, John A (2014). Roles of Small Laccases from Streptomyces in Lignin Degradation. Biochemistry, 53 (24), 4047−4058. DOI: 10.1021/bi500285t.
1.1.
2013
Li, Li; Palencia, Andrés; Lukk, Tiit; Li, Zhi; Luthey-Schulten, Zaida A; Cusack, Stephen; Martinis, Susan A; Boniecki, Michal T (2013). Leucyl-tRNA synthetase editing domain functions as a molecular rheostat to control codon ambiguity in Mycoplasma pathogens. Proceedings of the National Academy of Sciences, 110 (10), 3817−3822. DOI: 10.1073/pnas.1218374110.
1.1.
2013
Kelley, Stacy L; Lukk, Tiit; Nair, Satish K; Tapping, Richard I (2013). The crystal structure of human soluble CD14 reveals a bent solenoid with a hydrophobic amino-terminal pocket. The Journal of Immunology, 190 (3), 1304−1311. DOI: 10.4049/jimmunol.1202446.
1.1.
2012
Lukk, Tiit; Sakai, Ayano; Kalyanaraman, Chakrapani; Brown, Shoshana D; Imker, Heidi J; Song, Ling; Fedorov, Alexander A; Fedorov, Elena V; Toro, Rafael; Hillerich, Brandan; Seidel, Ronald; Patskovsky, Yury; Vetting, Matthew W; Nair, Satish K; Babbitt, Patricia C; Almo, Steven C; Gerlt, John A; Jacobson, Matthew P (2012). Homology models guide discovery of diverse enzyme specificities among dipeptide epimerases in the enolase superfamily. Proceedings of the National Academy of Sciences, 109 (11), 4122−4127. DOI: 10.1073/pnas.1112081109.
1.1.
2012
Gonzalez-Gutierrez, Giovanni; Lukk, Tiit; Agarwal, Vinayak; Papke, David; Nair, Satish K; Grosman, Claudio (2012). Mutations that stabilize the open state of the Erwinia chrisanthemi ligand-gated ion channel fail to change the conformation of the pore domain in crystals. Proceedings of the National Academy of Sciences, 109 (16), 6331−6336. DOI: 10.1073/pnas.1119268109.
1.1.
2012
Agarwal, Vinayak; Lin, Steven; Lukk, Tiit; Nair, Satish K; Cronan, John E (2012). Structure of the enzyme-acyl carrier protein (ACP) substrate gatekeeper complex required for biotin synthesis. Proceedings of the National Academy of Sciences, 109 (43), 17406−17411. DOI: 10.1073/pnas.1207028109.
6.05.2022

Tiit Lukk

https://www.etis.ee/CV/Tiit_Lukk/eng
29.04.1981
56776321
tiit.lukk@ttu.ee

Career

Institutions and positions
01.09.2017–...   
Tallinn University of Technology , School of Science, Department of Chemistry and Biotechnology, Senior Researcher (1,00)
01.01.2017–30.08.2017   
Tallinn University of Technology , School of Science, Department of Chemistry and Biotechnology, Researcher (1,00)
15.11.2016–31.12.2016   
Tallinn University of Technology , School of Science, Department of Chemistry and Biotechnology, specialist (1,00)
2013–31.10.2016   
Macromolecular Diffraction facility at the Cornell High Energy Synchrotron Source, Staff scientist at the Macromolecular Diffraction facility at the Cornell High Energy Synchrotron Source (1,00)
2009–2013   
University of Illinois at Urbana-Champaign, Postdoctoral research associate at the Energy Biosciences Institute and Institute for Genomic biology. (1,00)
2003–2004   
Estonian Biocentre, Assistant (1,00)
 
 
Education
2004–2009   
University of Illinois at Urbana-Champaign, doctorate studies in biochemistry, laboratory of John Gerlt, PhD in 2009
1999–2003   
University of Tartu, BSc, Department of Biology and Geography, major in biotechnology and biomedicine
 
 
R&D related managerial and administrative work
2022−...   
American Chemical Society, member
2021−...   
Guest editor of MDPI journal Energies
2020−...   
Member of the expert commission for natural sciences at Estonian research council
2020−...   
Member of the European Federation of Biotechnology
2019−...   
Estonian Biochemical Society, President
2018−...   
Estonian Biochemical Society, leadership
2018−...   
Estonian ambassador to the Federation of European Biochemical Societies
2018−...   
CA17128 LignoCOST - Establishment of a Pan-European Network on the Sustainable Valorisation of Lignin, management committee member
2017−...   
Member of the MSc defense committee at the Department of Chemistry and Biotechnology, Tallinn Univ. of Technology
2017−...   
Member of the PhD defense committee at the Department of Chemistry and Biotechnology, pre-reviewer, Tallinn Univ. of Technology
2022−2022   
Ogranizer of FEBS3+ meeting in June 2022 in Tallinn
2019−2019   
Estonian Biochemical Society 60 - organizer of the conference
2015−2015   
Organizer of the CHESS User Meeting Workshop "“Fast framing detectors and their applications in time-resolved crystallography/BioSAXS" at Cornell University

Qualifications

Academic degrees
Tiit Lukk, Doctor's Degree, 2009, (sup) John A. Gerlt, Discovery of Function in the Enolase Superfamily, University of Illinois at Urbana-Champaign
 
 
Fields of research
ETIS CLASSIFICATION: 4. Natural Sciences and Engineering; 4.12. Process Technology and Materials Science; CERCS CLASSIFICATION: T460 Wood, pulp and paper technology
ETIS CLASSIFICATION: 4. Natural Sciences and Engineering; 4.16. Biotechnology relating to Natural Sciences and Engineering; CERCS CLASSIFICATION: T360 Biochemical technology
ETIS CLASSIFICATION: 1. Biosciences and Environment; 1.1. Biochemistry; CERCS CLASSIFICATION: P310 Proteins, enzymology
 
 

Projects in progress

Dissertations under supervision

Supervised dissertations

Supervision of postdoctoral researchers

  • 01.01.2020−01.09.2021    Zeba Usmani  "Investigation of the role of actinobacteria in bioremediation processes and evolution of soil chemistry" (Tallinn University of Technology)

Publications

Category
Year
Publication
 
1.1.
2022
Usmani, Z.; Sharma, M.; Lukk, T.; Karpichev, Y.; Thakur, V. K.; Kumar, V.; Allaoui, A.; Awasthi, A. K.; Gupta, V. K. (2022). Developments in enzyme and microalgae based biotechniques to remediate micropollutants from aqueous systems—A review. Critical Reviews in Environmental Science and Technology, 52 (10), 1684−1729. DOI: 10.1080/10643389.2020.1862551.
1.1.
2022
Zovo, K.; Pupart, H.; Van Wieren, A.; Gillilan, R. E.; Huang, Q.; Majumdar, S.; Lukk, T. (2022). Substitution of the Methionine Axial Ligand of the T1 Copper for the Fungal-like Phenylalanine Ligand (M298F) Causes Local Structural Perturbations that Lead to Thermal Instability and Reduced Catalytic Efficiency of the Small Laccase from Streptomyces coelicolor A3(2). ACS Omega, 7 (7), 6184−6194. DOI: 10.1021/acsomega.1c06668.
1.1.
2022
Cronan, J. E.; Lukk, T. (2022). Advances in the Structural Biology, Mechanism and Physiology of Cyclopropane Fatty Acid Modification of Bacterial Membranes. Microbiology and Molecular Biology Reviews : Mmbr. DOI: 10.1128/mmbr.00013-22.
1.1.
2022
Jõul, P.; Ho, T. T.; Kallavus, U.; Konist, A.; Leiman, K.; Salm, O.-S.; Kulp, M.; Koel, M.; Lukk, T.; (2022). Characterization of Organosolv Lignins and Their Application in the Preparation of Aerogels. Materials, 15 (8), #2861. DOI: 10.3390/ma15082861.
5.2.
2022
Mohan, M.; Duvanova, E.; Lukk, T.; Karpichev, Y. (2022). Synthesis and antibacterial properties of lignin-based amino and quaternary ammonium surfactants. 5th International Symposium on Nanoparticles, Nanomaterials, and Applications 2002 (ISN2A 2022); Portugal, 24-27 January 2022. Ed. C. Lodeiro. Caparica-Portugal: PROTEOMASS Scientific Society (Portugal), 208.
1.1.
2021
Usmani, Zeba; Sharma, Minaxi; Awasthi, Abhishek Kumar; Sivakumar, Nallusamy; Lukk, Tiit; Pecoraro, Lorenzo; Thakur, Vijay Kumar; Roberts, Dave; Newbold, John; Gupta, Vijai Kumar (2021). Bioprocessing of waste biomass for sustainable product development and minimizing environmental impact. Bioresource Technology, 322, ARTN 124548. DOI: 10.1016/j.biortech.2020.124548.
1.1.
2021
Usmani, Z.; Kulp, M.; Lukk, T. (2021). Bioremediation of lindane contaminated soil: Exploring the potential of Actinobacterial strains. Chemosphere, 278, #130468. DOI: 10.1016/j.chemosphere.2021.130468.
1.1.
2021
Usmani, Z.; Sharma, M.; Awasthi, A. K.; Lukk, T.; Tuohy, M. G.; Gong, L.; Nguyen-Tri, P.; Goddard, A. D.; Bill, R. M.; Nayak, S. C.; Gupta, V. K. (2021). Lignocellulosic biorefineries: The current state of challenges and strategies for efficient commercialization. Renewable and Sustainable Energy Reviews, 148, #111258. DOI: 10.1016/j.rser.2021.111258.
1.1.
2021
Fujinami, D.; Garcia de Gonzalo, C. V.; Biswas, S.; Hao, Y.; Wang, H.; Garg, N.; Lukk, T.; Nair, S. K.; van der Donk, W. A. (2021). Structural and mechanistic investigations of protein S-glycosyltransferases. Cell Chemical Biology. DOI: 10.1016/j.chembiol.2021.06.009.
1.1.
2021
Usmani, Z.; Lukk, T.; Mohanachandran, D. K.; Thakur, V. K.; Gupta, V. K.; Robert, D.; Raj, J.; Scarpa, F.; Gupta, R. K. (2021). Biosafe sustainable antimicrobial encapsulation and coatings for targeted treatment and infections prevention: Preparation for another pandemic. Current Research in Green and Sustainable Chemistry, 4, #100074. DOI: 10.1016/j.crgsc.2021.100074.
1.1.
2019
Ernits, Karin; Eek, Priit; Lukk, Tiit; Visnapuu, Triinu; Alamäe, Tiina (2019). First crystal structure of an endo-levanase – the BT1760 from a human gut commensal Bacteroides thetaiotaomicron. Scientific Reports, 9 (1), 8443. DOI: 10.1038/s41598-019-44785-0.
5.2.
2019
Ernits, K.; Eek, P.; Lukk, T.; Visnapuu, T., Alamäe, T. (2019). First crystal structure of a bacterial endo-levanase. In: (22−22). FEBS+ conference of Latvian, Lithuanian and Estonian Biochemical Societies. 17-19 June 2019. Riga, Latvia: University of Latvia.
1.1.
2016
Lukk, Tiit; Gillilan, Richard E; Szebenyi, Doletha M E; Zipfel, Warren R (2016). A visible-light-excited fluorescence method for imaging protein crystals without added dyes. Journal of Applied Crystallography, 49 (Pt 1), 234−240.
1.1.
2015
Garg, Aprajita; Lukk, Tiit; Kumar, Vidya; Choi, Jae-Yeon; Augagneur, Yoann; Voelker, Dennis R; Nair, Satish; Ben Mamoun, Choukri (2015). Structure, function and inhibition of the phosphoethanolamine methyltransferases of the human malaria parasites Plasmodium vivax and Plasmodium knowlesi. Scientific Reports, 5, 9064−9064. DOI: 10.1038/srep09064.
1.1.
2015
Dong, Shi-Hui; Tang, Weixin; Lukk, Tiit; Yu, Yi; Nair, Satish K; van der Donk, Wilfred A (2015). The enterococcal cytolysin synthetase has an unanticipated lipid kinase fold. eLife, 4, 1−18. DOI: 10.7554/eLife.07607.
1.1.
2015
Organtini, Lindsey J; Allison, Andrew B; Lukk, Tiit; Parrish, Colin R; Hafenstein, Susan (2015). Global displacement of canine parvovirus by a host-adapted variant: structural comparison between pandemic viruses with distinct host ranges. Journal of Virology, 89 (3), 1909−1912. DOI: 10.1128/JVI.02611-14.
1.1.
2014
Wichelecki, Daniel J; Balthazor, Bryan M; Chau, Anthony C; Vetting, Matthew W; Fedorov, Alexander A; Fedorov, Elena V; Lukk, Tiit; Patskovsky, Yury V; Stead, Mark B; Hillerich, Brandan S; Seidel, Ronald D; Almo, Steven C; Gerlt, John A (2014). Discovery of function in the enolase superfamily: D-mannonate and d-gluconate dehydratases in the D-mannonate dehydratase subgroup. Biochemistry, 53 (16), 2722−2731. DOI: 10.1021/bi500264p.
1.1.
2014
Majumdar, Sudipta; Lukk, Tiit; Solbiati, Jose O; Bauer, Stefan; Nair, Satish K; Cronan, John E; Gerlt, John A (2014). Roles of Small Laccases from Streptomyces in Lignin Degradation. Biochemistry, 53 (24), 4047−4058. DOI: 10.1021/bi500285t.
1.1.
2013
Li, Li; Palencia, Andrés; Lukk, Tiit; Li, Zhi; Luthey-Schulten, Zaida A; Cusack, Stephen; Martinis, Susan A; Boniecki, Michal T (2013). Leucyl-tRNA synthetase editing domain functions as a molecular rheostat to control codon ambiguity in Mycoplasma pathogens. Proceedings of the National Academy of Sciences, 110 (10), 3817−3822. DOI: 10.1073/pnas.1218374110.
1.1.
2013
Kelley, Stacy L; Lukk, Tiit; Nair, Satish K; Tapping, Richard I (2013). The crystal structure of human soluble CD14 reveals a bent solenoid with a hydrophobic amino-terminal pocket. The Journal of Immunology, 190 (3), 1304−1311. DOI: 10.4049/jimmunol.1202446.
1.1.
2012
Lukk, Tiit; Sakai, Ayano; Kalyanaraman, Chakrapani; Brown, Shoshana D; Imker, Heidi J; Song, Ling; Fedorov, Alexander A; Fedorov, Elena V; Toro, Rafael; Hillerich, Brandan; Seidel, Ronald; Patskovsky, Yury; Vetting, Matthew W; Nair, Satish K; Babbitt, Patricia C; Almo, Steven C; Gerlt, John A; Jacobson, Matthew P (2012). Homology models guide discovery of diverse enzyme specificities among dipeptide epimerases in the enolase superfamily. Proceedings of the National Academy of Sciences, 109 (11), 4122−4127. DOI: 10.1073/pnas.1112081109.
1.1.
2012
Gonzalez-Gutierrez, Giovanni; Lukk, Tiit; Agarwal, Vinayak; Papke, David; Nair, Satish K; Grosman, Claudio (2012). Mutations that stabilize the open state of the Erwinia chrisanthemi ligand-gated ion channel fail to change the conformation of the pore domain in crystals. Proceedings of the National Academy of Sciences, 109 (16), 6331−6336. DOI: 10.1073/pnas.1119268109.
1.1.
2012
Agarwal, Vinayak; Lin, Steven; Lukk, Tiit; Nair, Satish K; Cronan, John E (2012). Structure of the enzyme-acyl carrier protein (ACP) substrate gatekeeper complex required for biotin synthesis. Proceedings of the National Academy of Sciences, 109 (43), 17406−17411. DOI: 10.1073/pnas.1207028109.
6.05.2022