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Olen nõus
19.07.1980
urmas@roostalu.info

Teenistuskäik

Töökohad ja ametid
01.02.2015–...   
University of Manchester, Teadur/Vanemteadur (Research Fellow) (1,00)
01.01.2014–30.01.2015   
University of Manchester, Järeldoktor (1,00)
01.05.2013–31.12.2013   
University College London, Järeldoktor (1,00)
11.11.2011–30.04.2013   
KIng's College London, Järeldoktor (1,00)
 
 
Haridustee
1998–21.06.2002   
Bioloogia õpingud Tartu Ülikoolis, BSc zooloogia erialal.
 
 
Teadusorganisatsiooniline ja -administratiivne tegevus
2016−2017   
Membership in the Society of Differentiation and in the International Society of Stem Cell Research
 
 
Loometöö
Dr. Urmas Roostalu teadustöö eesmärgiks on selgitada rakkude plastilisuse ja varase differentseerumise molekulaarseid mehhanisme ning seda, kuidase neid saab kasutada erinevate kudede regeneratsioonis. Oluliseks uurimistöö suunaks on olnud lihasrakkude vigastuste molekulaarne analüüs ja tüvirakuteraapia arendamine Duchenne’I lihasdüstroofia raviks. Viimaste aastate teadustöö on aga rohkem keskendunud ka veresoontega seotud eellasrakkude avastamisele ja kirjeldamisele, kuna veresooned loovad organismis sobiva rakkude plastilisust soosiva keskonna. Nende rakkude parem kirjeldamine võib luua uudseid võimalusi veresoonkonna haiguste raviks, kuid ka nende rakkude suunamiseks muude kudede regeneratsiooni parandamiseks..
 
 
Teenistuskäigu lisainfo
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Kvalifikatsioon

Teaduspreemiad ja tunnustused
2014, Urmas Roostalu, Suurbritannia Biotehnoloogia ja Bioloogiliste Teaduste Nõukogu isiklik uurimistoetus kolmeks aastaks (Tuleviku Liidri Teaduspreemia, £294,000)
2007, Urmas Roostalu, Boehringer Ingelheimi fondi doktorandistipendium
 
 
Teadustöö põhisuunad
VALDKOND: 1. Bio- ja keskkonnateadused; 1.3. Geneetika; CERCS ERIALA: B220 Geneetika, tsütogeneetika ; PÕHISUUND: Tüvirakud, rakkude differentseerumine
VALDKOND: 1. Bio- ja keskkonnateadused; 1.3. Geneetika; CERCS ERIALA: B220 Geneetika, tsütogeneetika ; PÕHISUUND: Arengubioloogia, lihaste ja veresoonkonna areng
VALDKOND: 3. Terviseuuringud; 3.1. Biomeditsiin; CERCS ERIALA: B726 Kliiniline bioloogia ; PÕHISUUND: Lihasdüstroofia diagnostika ja ravi
 
 
Lisainfo
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26.06.2018
19.07.1980
urmas@roostalu.info
Division of Extracellular Matrix and Regenerative Medicine
Faculty of Biology, Medicine and Health
Michael Smith Bldg. Oxford Road
University of Manchester
Manchester M13 9PL, UK

Career

Institution and occupation
01.02.2015–...   
University of Manchester, Biotechnology and Biological Sciences Research Council (BBSRC) Research Fellow (1,00)
01.01.2014–30.01.2015   
University of Manchester, Postdoctoral Research Associate (1,00)
01.05.2013–31.12.2013   
University College London, Postdoctoral Research Associate (1,00)
11.11.2011–30.04.2013   
KIng's College London, Postdoctoral Research Associate (1,00)
 
 
Education
1998–21.06.2002   
BSc (Baccalaureus scientiarum) in zoology from the University of Tartu
 
 
R&D related managerial and administrative work
2016−2017   
Membership
 
 
Creative work
Dr. Urmas Roostalu is British Biotechnology and Biological Sciences Research Council (BBSRC) Future Leader fellow at the University of Manchester. He received BSc (2002) and MSc (2004) degrees in Biology from the University of Tartu, Estonia. He was awarded Boehringer Ingelheim Foundation fellowship to continue PhD studies at the University of Heidelberg in Germany. Under the guidance of Prof. Uwe Strähle his studies in Heidelberg and at the Karlsruhe Institute of Technology focused on skeletal muscle regeneration in zebrafish. He developed novel methods to inflict microscopic membrane lesions to muscle cells by high-precision laser beams in order to study the molecular injury response in real time. Urmas was awarded PhD in 2011. His postdoctoral training in the group of Prof. Frederic Geissmann at King’s College London (2011-2013) was targeting the molecular regulation of immune response in flies and humans. In 2013 he joined the group of Prof. Giulio Cossu at the University College London and since 2014 at the University of Manchester to focus on the biology of vascular and skeletal muscle cells and on stem cell therapy for Duchenne muscular dystrophy. He was awarded BBSRC Anniversary Future Leader fellowship, which he started in February, 2015. Urmas is interested in the role that cellular plasticity plays in organ development, maintenance and regeneration. Using complex transgenic mouse models his research is aimed at revealing the extent to which perivascular cells contribute to the growth and homeostasis of diverse organs. He is also working on the principal molecular mechanisms of early cell differentiation..
 
 
Additional career information
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Qualifications

Honours & awards
2014, Urmas Roostalu, Biotechnology and Biological Sciences Research Council (BBSRC), Anniversary Future Leader Fellowship. 3 year research grant of £294,000.
2007, Urmas Roostalu, Boehringer Ingelheim Foundation PhD Fellowship
 
 
Field of research
FIELD OF RESEARCH: 1. Biosciences and Environment; 1.3. Genetics; CERCS SPECIALTY: B220 Genetics, cytogenetics ; SPECIALITY: Stem cell research, Cell differentiation
FIELD OF RESEARCH: 1. Biosciences and Environment; 1.3. Genetics; CERCS SPECIALTY: B220 Genetics, cytogenetics ; SPECIALITY: Developmental biology (skeletal muscles, vasculature)
FIELD OF RESEARCH: 3. Health; 3.1. Biomedicine; CERCS SPECIALTY: B726 Clinical biology ; SPECIALITY: Molecular diagnostics and therapies for muscular dystrophies
 
 
Additional information
26.06.2018
  • Leitud 1 kirjet
ProgrammLiikNumberNimiProjekti algusProjekti lõppVastutav täitjaAsutusFinantseerijapoolne rahastamine
ETFETF6040Eestlaste ema- ja isaliinid fülogeograafilises kontekstis01.01.200531.12.2010Kristiina TambetsEesti Biokeskus53 191,16 EUR