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Olen nõus

Ursel Soomets

https://www.etis.ee/CV/Ursel_Soomets/est
18.07.1962
15.01.2022

Teenistuskäik

Töökohad ja ametid
01.01.2021–15.01.2022   
Tartu Ülikool, Meditsiiniteaduste valdkond, bio- ja siirdemeditsiini instituut, meditsiinilise metaboloomika professor (1,00)
01.02.2020–31.12.2020   
Tartu Ülikool, Meditsiiniteaduste valdkond, bio- ja siirdemeditsiini instituut, meditsiinilise metaboloomika professor (0,60)
01.02.2020–31.12.2020   
Tartu Ülikool, Meditsiiniteaduste valdkond, bio- ja siirdemeditsiini instituut, üldise biokeemia vanemteadur (0,40)
01.01.2016–31.01.2020   
Tartu Ülikool, Meditsiiniteaduste valdkond, bio- ja siirdemeditsiini instituut, meditsiinilise metaboloomika professor (0,50)
01.01.2016–31.01.2020   
Tartu Ülikool, Meditsiiniteaduste valdkond, bio- ja siirdemeditsiini instituut, üldise biokeemia vanemteadur (0,50)
01.02.2015–31.12.2015   
Tartu Ülikool, Arstiteaduskond, Biomeditsiini instituut, meditsiinilise metaboloomika professor (0,50)
01.02.2015–31.12.2015   
Tartu Ülikool, Arstiteaduskond, Biomeditsiini instituut, üldise biokeemia vanemteadur (0,50)
21.05.2013–31.01.2015   
Tartu Ülikool, Arstiteaduskond, Biomeditsiini instituut, meditsiinilise metaboloomika professor (0,50)
21.05.2013–31.01.2015   
Tartu Ülikool, Arstiteaduskond, Biomeditsiini instituut, üldise biokeemia vanemteadur (0,50)
01.02.2010–20.05.2013   
Tartu Ülikool, Arstiteaduskond, Biokeemia instituut, üldise biokeemia vanemteadur (0,50)
01.02.2010–20.05.2013   
Tartu Ülikool, Arstiteaduskond, Biokeemia instituut, meditsiinilise metaboloomika professor (0,50)
01.02.2010–21.01.2015   
Tartu Ülikool, Arstiteaduskond, Arstiteaduskonna dekanaat, biomeditsiini magistriõppe programmijuht
01.01.2008–31.12.2013   
Psühhiaatria Instituut, King's Kolledz, Londoni Ülikool; külalislektor
22.07.2006–21.12.2006   
Tartu Ülikool, Arstiteaduskond, Molekulaarse ja kliinilise meditsiini keskus, erakorraline vanemteadur (1,00)
01.02.2005–31.01.2010   
Tartu Ülikool, Arstiteaduskond, Biokeemia instituut, üldise biokeemia dotsent (0,50)
01.02.2005–31.01.2010   
Tartu Ülikool, Arstiteaduskond, Biokeemia instituut, üldise biokeemia vanemteadur (0,50)
01.05.2000–31.01.2005   
Tartu Ülikool, Arstiteaduskond, Biokeemia instituut, üldise biokeemia dotsent (0,50)
01.05.2000–31.01.2005   
Tartu Ülikool, Arstiteaduskond, Biokeemia instituut, üldise biokeemia vanemteadur (0,50)
01.01.2000–31.12.2005   
Tartu Ülikool, Arstiteaduskond, Biokeemia instituut, dotsent (1/2 kohta); vanemteadur (1/2 kohta)
01.01.1991–31.12.1991   
Tartu Riiklik Ülikool, Ensümoloogia labor, vaneminsener
01.01.1991–31.12.2000   
Tartu Ülikool, Arstiteaduskond, Biokeemia instituut, vanem-assistent (vanem-õpetaja)
01.01.1987–31.12.1990   
Tartu Riiklik Ülikool, Orgaanilise keemia kateeder, aspirant (statsionaar)
01.01.1987–31.12.1987   
Tartu Riiklik Ülikool, bioorgaanilse keemia labor, insener
01.01.1985–31.12.1987   
Tartu Riiklik Ülikool, Orgaanilise keemia kateeder, stazöör-uurija
 
 
Haridustee
1998–2000   
Stockholmi Ülikooli Neurokeemia ja neurotoksikoloogia instituudi doktorant
1996–2000   
Tartu Ülikooli Arstiteaduskonna Biokeemia kateedri üldise biokeemia eriala doktorant
1980–1985   
Tartu Riiklik Ülikool; keemik (bio-orgaanilise- ja biokeemia eriprogramm)
 
 
Teadusorganisatsiooniline ja -administratiivne tegevus
2013−...   
TÜ Arstiteaduskonna Bio- ja siirdemedtisiini instituudi nõukogu liige
2013−...   
Sihtasutus Eesti Akrediteerimiskeskuse assessor
2005−...   
TÜ Neuroteaduste kraadinõukogu liige
2011−2016   
Tartu Ülikooli Siirdegenoomika keskuse (CTG) tegevjuht
2010−2015   
Eesti Biokeemia seltsi juhatuse liige
2008−2015   
Tippkeskuse "Siirdeuuringud neuroimmunoloogiliste haiguste paremaks diagnostikaks ja raviks" nõukogu liige
2008−2014   
TÜ Arstiteaduskonna Biomeditsiini magistriõppe kraadinõukogu esimees
2003−2011   
ETF terviseuuringute ekspertkomisjoni liige

Kvalifikatsioon

Teaduskraadid
Ursel Soomets, doktorikraad, 2000, (juh) Ülo Langel; Mihkel Zilmer, Development of novel transport peptides and their application in antisense techniques, Stockholmi Ülikool (University of Stockholm).
Ursel Soomets, magistrikraad (teaduskraad), 1994, (juh) Uno Mäeorg, Synthesis of 4,4'-dibromobenzilic acid and its derivatives, Tartu Ülikool.
 
 
Teaduspreemiad ja tunnustused
2012, Ursel Soomets, Tartu Ülikooli väike medal
2010, Ursel Soomets, Tartu Ülikooli Kliinikumi Teadustööpreemia (töörühmas koos K. Joosti, T. Kahre, K. Kilk'i,M.-L. Uudeleppa, K. Õunapiga)
2009, Ursel Soomets, Eesti Riiklik Teaduspreemia keemia ja molekulaarbioloogia valdkonnas (töörühmas koos Ü. Langeli, M. Pooga, K. Kilk'i ja M. Hanseniga)
2008, Ursel Soomets, Tartu Ülikooli aumärk
 
 
Teadustöö põhisuunad
ETIS KLASSIFIKAATOR: 3. Terviseuuringud; 3.1. Biomeditsiin; CERCS KLASSIFIKAATOR: B470 Füsioloogia ; TÄPSUSTUS: Neuroimmunoloogiliste ja kaasasündinud haiguste metaboloomilised uuringud, mitmete erinevate organismide ja kudede metaboloomne profileerimine leidmaks uusi biomarekereid, Wolframi tõve loommudelite kirjeldamine, oksüdatiivne stress, peptiidsed ja mittepeptiidsed antioksüdandid kui ravimeellased, ajukoe uuringud erinevate haiguste korral või narkootikumide kasutamisel.
 
 
Lisainfo
Olen Ameerika Peptiidi Ühingu liige; Eesti Biokeemia Seltsi liige;
Osalen meie teadusgrupi koostööprojektides väljaspool Eestit: Stockholmi Ülikooliga, Londoni Kings Kolledžiga, Ljubljana Ülikooliga, SCRIPPS instituudiga (USA), Wolverhamptoni Ülikooliga; -
Eestis: Eesti Biotsenter, Tallinna Tehnikaülikool, TÜ Arengubioloogia instituut, TÜ Füsioloogia instituut, Tallinna Lastehaigla, TÜ Lastekliinik, SA Tartu Ülikooli Kliinikumi (TÜK) Ühendlabori meditsiinigeneetika Keskus

Lõppenud projektid

Juhendamisel väitekirjad

Juhendatud väitekirjad

Publikatsioonid

1.1. Teadusartiklid, mis on kajastatud Web of Science andmebaasides Science Citation Index Expanded, Social Sciences Citation Index, Arts & Humanities Citation Index, Emerging Sources Citation Index ja/või andmebaasis Scopus (v.a. kogumikud)
 
Ilves, Liis; Ottas, Aigar; Kaldvee, Bret; Abram, Kristi; Soomets, Ursel; Zilmer, Mihkel; Reemann, Paula; Jaks, Viljar; Kingo, Külli (2021). The metabolomic analysis of skin biopsies from atopic dermatitis patients reveals hallmarks of inflammation, disrupted barrier function and oxidative stress. Acta Dermato Venereologica, 101 (2). DOI: /doi.org/10.2340/00015555-3766.
 
Kairane, C.; Mahlapuu, R.; Porosk, R.; Zilmer, M.; Soomets, U. (2019). The effects of glutathione analogues on Na,K-ATPase activity in the kidneys of the wildtype and the Wfs1 gene mutated mice in vitro and in vivo. Journal of Peptide Science, 223−225. DOI: 10.17952/35EPS.2018.223.
 
Nõmm, Monika; Porosk, Rando; Pärn, Pille; Kilk, Kalle; Soomets, Ursel; Kõks, Sulev; Jaakma, Ülle (2019). Invitro culture and non-invasive metabolic profiling of single bovine embryos. Reproduction Fertility and Development, 31 (2), 306−314. DOI: 10.1071/RD17446.
 
Hansen, Mats; Porosk, Rando; Mahlapuu, Riina; Kairane, Ceslava; Kilk, Kalle; Soomets, Ursel (2019). GSH Synthetic Analogue O-Methyl-L-Tyrosinylglutathione Regulates Nrf2-Mediated Expression of GCLc and GCLm. Journal of Chemistry, ARTN 3841219. DOI: 10.1155/2019/3841219.
 
Ottas, Aigar; Fishman, Dmytro; Okas, Tiia-Linda; Kingo, Külli; Soomets, Ursel; (2017).

The metabolic analysis of psoriasis identifies the associated metabolites while providing computational models for the monitoring of the disease

. Archives of Dermatological Research, 309 (7), 519−528. DOI: 10.1007/s00403-017-1760-1.
 
Porosk, R.; Mahlapuu, R.; Terasmaa, A.; Kilk, K.; Soomets, U. (2017). Glutathione system in Wolfram syndrome 1‑deficient mice. Molecular Medicine Reports, 7092−7097. DOI: 10.3892/mmr.2017.7419.
 
Porosk, R.; Terasmaa, A.; Mahlapuu, R.; Soomets, U.; Kilk, K. (2017). Metabolomics of the Wolfram Syndrome 1 Gene (Wfs1) Deficient Mice. OMICS A Journal of Integrative Biology, 21 (2), 721−732. DOI: 10.1089/omi.2017.0143.
 
Ottas, Aigar; Fishman, Dmytro; Okas, Tiia-Linda; Pussa, Tonu; Toomik, Peeter; Martson, Aare; Kingo, Kulli; Soomets, Ursel (2017).

Blood serum metabolome of atopic dermatitis: Altered energy cycle and the markers of systemic inflammation

. PLoS ONE, 12 (11), ARTN e0188580. DOI: 10.1371/journal.pone.0188580.
 
Kriisa, Kärt; Leppik, Liisa; Balõtšev, Roman; Ottas, Aigar; Soomets, Ursel; Koido, Kati; Volke, Vallo; Innos, Jürgen; Haring, Liina; Vasar, Eero; Zilmer, Mihkel (2017). Profiling of Acylcarnitines in First Episode Psychosis before and after Antipsychotic Treatment. Journal of Proteome Research, 16 (10), 3558−3566. DOI: 10.1021/acs.jproteome.7b00279.
 
Asser, Andres; Kõks, Sulev; Snellman, Anniina; Haaparanta-Solin, Merja; Arponen, Eveliina; Grönroos, Tove; Nairismägi, Jaak; Bergquist, Jonas; Soomets, Ursel; Piip, Piret; Eltermaa, Mall; Sauk, Martin; Lindmäe, Hanna; Rinne, Juha O; Taba, Pille (2016). Increased striatal VMAT2 binding in mice after chronic administration of methcathinone and manganese. Brain Research, 1652, 97−102. DOI: 10.1016/j.brainres.2016.09.034.
 
Kazarjan, J.; Mahlapuu, R.; Hansen, M.; Soomets, U.; Kaljurand, M.; Vaher, M. (2015). Investigation of the surfactant type and concentration effect on the retention factors of glutathione and its analogues by micellar electrokinetic chromatography. Journal of Separation Science, 38 (19), 3461−3468. DOI: 10.1002/jssc.201500567.
 
Zagura, Maksim; Kals, Jaak; Kilk, Kalle; Serg, Martin; Kampus, Priit; Eha, Jaan; Soomets, Ursel; Zilmer, Mihkel. (2015). Metabolomic signature of arterial stiffness in male patients with peripheral arterial disease. Hypertension Research, 38 (12), 840−846.
 
Kilk, Kalle; Meitern, Richard; Härmson, Oliver; Soomets, Ursel; Hõrak, Peeter (2014). Assessment of oxidative stress in serum by d-ROMs test. Free Radical Research, 48 (8), 883−889. DOI: 10.3109/10715762.2014.919390.
 
Aug, A.; Altraja, A.; Altraja, S.; Laaniste, L.; Mahlapuu, R.; Soomets, U.; Kilk, K. (2014). Alterations of bronchial epithelial metabolome by cigarette smoke are reversible by an antioxidant, O-methyl-L-tyrosinyl-γ-L-glutamyl-L-cysteinylglycine. American Journal of Respiratory Cell and Molecular Biology, 51 (4), 586−594. DOI: 10.1165/rcmb.2013-0377OC.
 
Punapart, Marite; Eltermaa, Mall; Oflijan, Julia; Sütt, Silva; Must, Anne; Kõks, Sulev; Schalkwyk, Leonard C.; Fernandes, Catherine; Vasar, Eero; Soomets, Ursel; Terasmaa, Anton (2014). Effect of Chronic Valproic Acid Treatment on Hepatic Gene Expression Profile in Wfs1 Knockout Mouse. PPAR Research, 2014, 349525. DOI: 10.1155/2014/349525.
 
Kairane, C.; Mahlapuu, R.; Ehrlich, K.; Zilmer, M.; Soomets, U. (2014). The effects of different antioxidants on the activity of Cerebrocortical MnSOD and Na,K-ATPase from post mortem alzheimer´s disease and age-matched normal brains. Current Alzheimer Research, 11 (1), 79−85.10.2174/15672050113106660179.
 
Oit-Wiscombe, I.; Virag, L.; Soomets, U.; Altraja, A. (2013). Increased DNA damage in progression of COPD: a response by poly(ADP-ribose) polymerase-1. PLoS ONE, 8, e70333.
 
Harzia, Hedi; Ilves, Aire; Ots, Meelis; Henno, Merike; Jõudu, Ivi; Kaart, Tanel; Ling, Katri; Kärt, Olav; Kilk, Kalle; Soomets, Ursel (2013). Alterations in milk metabolome and coagulation ability during the lactation of dairy cows. Journal of Dairy Science, 96 (10), 6440−6448. DOI: 10.3168/jds.2013-6808.
 
Kazarjan, J.; Vaher, M.; Mahlapuu, R.; Hansen, M.; Soomets, U.; Kaljurand, M. (2013). Separation of glutathione and its novel analogues and determination of their dissociation constants by capillary electrophoresis. Electrophoresis, 34 (12), 1820−1827. DOI: 10.1002/elps.201200611.
 
Kõks, S.; Overall, R.W.; Ivask, M.; Soomets, U.; Guha, M.; Vasar, E.; Fernandes, C.; Schalkwyk, L.C. (2013). Silencing of the WFS1 gene in HEK cells induces pathways related to neurodegeneration and mitochondrial damage. Physiological Genomics, 45 (5), 182−190. DOI: 10.1152/physiolgenomics.00122.2012.
 
Harzia, Hedi; Kilk, Kalle; Ariko, Tiia; Kass, Marko; Soomets, Ursel; Jõudu, Ivi; Kaart, Tanel; Arney, David; Kärt, Olav; Ots, Meelis (2013). Crude glycerol as a glycogenic precursor in feed: effects on milk coagulation properties and metabolic profiles of dairy cows. Journal of Dairy Research, 80 (2), 190−196. DOI: 10.1017/S0022029913000101.
 
Laanemets, Kristiina; Wang, Yong-Fei; Lindgren, Ove; Wu, Juyou; Nishimura, Noriyuki; Lee, Stephen; Caddell, Daniel; Merilo, Ebe; Brosche, Mikael; Kilk, Kalle; Soomets, Ursel ; Kangasjarvi, Jaakko; Schroeder, Julian I.; Kollist, Hannes (2013). Mutations in the SLAC1 anion channel slow stomatal opening and severely reduce K+ uptake channel activity via enhanced cytosolic [Ca2+] and increased Ca2+ sensitivity of K+ uptake channels. New Phytologist, 197 (1), 88−98. DOI: 10.1111/nph.12008.
 
Altraja, S.; Mahlapuu, R.; Soomets, U.; Altraja, A. (2013). Cigarette smoke-induced differential regulation of glutathione metabolism in bronchial epithelial cells is balanced by an antioxidant tetrapeptide UPF1. Experimental and Toxicologic Pathology, 65 (6), 711−717. DOI: 10.1016/j.etp.2012.09.005.
 
Joost, K.; Rodenburg, R.J.; Piirsoo, A.; van den Heuvel, L.; Žordania, R.; Põder, H.; Talvik, I.; Kilk, K.; Soomets, U.; Õunap, K. (2012). A Diagnostic Algorithm for Mitochondrial Disorders in Estonian Children. Molecular Syndromology, 3 (3), 113−119. DOI: 10.1159/000341375.
 
Ilves, Aire; Harzia, Hedi; Ling, Katri; Ots, Meelis; Soomets, Ursel; Kilk, Kalle (2012). Alterations in milk and blood metabolomes during the first months of lactation in dairy cows. Journal of Dairy Science, 95 (10), 5788−5797. DOI: 10.3168/jds.2012-5617.
 
Joost, K.; Õunap, K.; Žordania, R.; Uudelepp, M.-L.; Olsen, R.K.; Kall, K.; Kilk, K.; Soomets, U.; Kahre, T. (2012). Prevalence of long-chain 3-hydroxyacyl-CoA dehydrogenase deficiency in Estonia. JIMD Reports, 2, 79−85.
 
Harzia, H.; Kilk, K.; Jõudu, I.; Henno, M.; Kärt, O.; Soomets, U. (2012). Comparison of the metabolic profiles of noncoagulating and coagulating bovine milk. Journal of Dairy Science, 95 (2), 533−544. DOI: 10.3168/jds.2011-4468.
 
Kõks, S.; Soomets, U.; Plaas, M.; Terasmaa, A.; Noormets, K.; Tillmann, V.; Vasar, E.; Fernandes, C.; Schalkwyk, LC. (2011). Hypothalamic gene expression profile indicates a reduction in G protein signaling in the Wfs1 mutant mice. Physiological Genomics, 43, 1351−1358. DOI: 10.1152/physiolgenomics.00117.2011.
 
Terasmaa, A.; Soomets, U.; Oflijan, J.; Punapart, M.; Hansen, M.; Matto, V.; Ehrlich, K.; Must, A.; Kõks, S.; Vasar, E. (2011). Wfs1 mutation makes mice sensitive to insulin-like effect of acute valproic acid and resistant to streptozocin. Journal of Physiology and Biochemistry, 67 (3), 381−390. DOI: 10.1007/s13105-011-0088-0.
 
Sikk, K.; Kõks, S.; Soomets, U.; Schalkwyk, L.C.; Fernandes, C.; Haldre, S.; Aquilonius, S.M.; Taba, P. (2011). Peripheral blood RNA expression profiling in illicit methcathinone users reveals effect on immune system. Frontiers in Genetics, 2, 42.
 
Kõks, S.; Velthut, A.; Sarapik, A.; Altmäe, S.; Reinmaa, E.; Schalkwyk, L.C.; Fernandes, C.; Lad, H.V.; Soomets, U.; Jaakma, Ü.; Salumets, A. (2010). The differential transcriptome and ontology profiles of mural and cumulus granulosa cells in stimulated human antral follicles. Molecular Human Reproduction, 16 (4), 229−240. DOI: 10.1093/molehr/gap103.
 
Hõrak, P.; Sild, E.; Soomets, U.; Sepp, T.; Kilk, K. (2010). Oxidative stress and information content of black and yellow plumage coloration: an experiment with greenfinches. Journal of Experimental Biology, 213, 2225−2233. DOI: 10.1242/jeb.042085.
 
Viirlaid, S.; Mahlapuu, R.; Kilk, K.; Kuznetsov, A.; Soomets, U.; Järv, J. (2009). Mechanism and stoichiometry of 2,2-diphenyl-1-picrylhydrazyl radical scavenging by glutathione and its novel a-glutamylderivative. Bioorganic Chemistry, 37, 126−132. DOI: 10.1016/j.bioorg.2009.05.001.
 
Meszka-Jordan, A.; Mahlapuu, R.; Soomets, U.; Carlson, G. P. (2009). Oxidative Stress Due to (R)-Styrene Oxide Exposure and the Role of Antioxidants in Non-Swiss Albino (NSA) Mice. Journal of Toxicology and Environmental Health Part A, 72 (10), 642−650. DOI: 10.1080/15287390902769436.
 
Ehrlich, K.; Ida, K.; Mahlapuu, R.; Kairane, C.; Oit, I.; Zilmer, M.; Soomets, U. (2009). Characterization of UPF peptides, members of the glutathione analogues library, on the basis of their effects on oxidative stress-related enzymes. Free Radical Research, 43 (6), 572−580. DOI: 10.1080/10715760902918691.
 
Kilk, K.; Mahlapuu, R.; Soomets, U.; Langel, Ü. (2009). Analysis of in vitro toxicity of five cell-penetrating peptides by metabolic profiling. Toxicology, 265 (3), 87−95.
 
Koks, S.; Soomets, U.; Paya-Cano, J.; Fernandes, C.; Luuk, H.; Plaas, M.; Terasmaa, A.; Tillmann, V.; Noormets, K.; Vasar, E.; Schalkwyk, LC. (2009). Wfs1 gene deletion causes growth retardation in mice and interferes with the growth hormone pathway. Physiological Genomics, 37, 3, 249−259.
 
Kals, J.; Starkopf, J.; Zilmer, M.; Pruler, T.; Pulges, K.; Hallaste, M.; Kals, M.; Pulges, A.; Soomets, U. (2008). Antioxidant UPF1 attenuates myocardial stunning in isolated rat hearts. International Journal of Cardiology, 125 (1), 133−135. DOI: 10.1016/j.ijcard.2007.01.032.
 
Kingo, K.; Aunin, E.; Karelson, M.; Philips, MA; Rätsep, R.; Silm, H.; Vasar, E.; Soomets, U.: Kõks S. (2007). Gene expression analysis of melanocortin system in vitiligo. Journal of Dermatological Science, 48 (2), 113−122.
 
Ehrlich, K.; Viirlaid, S.; Mahlapuu, R.; Saar, K.; Kullisaar, T.; Zilmer, M.; Langel, Ü.; Soomets, U. (2007). Design, synthesis and properties of novel powerful antioxidants, glutathione analogues. Free Radical Research, 41 (7), 779−787.
 
Vaher, Merike; Viirlaid, Säde; Ehrlich, Kersti; Mahlapuu, Riina; Jarvet, Jüri; Soomets, Ursel; Kaljurand, Mihkel. (2006). Characterization of the antioxidative activity of novel nontoxic neuropeptides by using capillary electrophoresis. Electrophoresis, 13, 2582−2589.
 
Mahlapuu, R.; Vaher, M.; Ehrlich, K.; Kaljurand, M.; Soomets, U. (2006). Comparison of stability of glutathione and related synthetic tetrapeptides by HPLC and capillary electrophoresis. Journal of Peptide Science, 12 (12), 796−799.
 
Hallbrink, M.; Kilk, K.; Elmquist, A.; Lundberg, P.; Lindgren, M.; Jiang, Y.; Pooga, M.; Soomets, U.; Langel, U. (2005). Prediction of cell-penetrating peptides. International Journal of Peptide Research and Therapeutics, 11 (4), 249−259.
 
Poder, P.; Zilmer, M.; Starkopf, J.; Kals, J.; Talonpoika, A.; Pulges, A.; Langel, U.; Kullisaar, T.; Viirlaid, S.; Mahlapuu, R.; Zarkovski, A.; Arend, A.; Soomets, U. (2004). An antioxidant tetrapeptide UPF1 in rats has a neuroprotective effect in transient global brain ischemia. Neuroscience Letters, 370 (1), 45−50.
 
Fisher, L.; Soomets, U.; Toro, V.C.; Chilton, L.; Jiang, Y.; Langel, U.; Iverfeldt, K. (2004). Cellular delivery of a double-stranded oligonucleotide NF kappa B decoy by hybridization to complementary PNA linked to a cell-penetrating peptide. Gene Therapy, 11 (16), 1264−1272.
 
Kilk, K.; Elmquist, A.; Saar, K.; Pooga, M.; Land, T.; Bartfai, T.; Soomets, U.; Langel, U. (2004). Targeting of antisense PNA oligomers to human galanin receptor type 1 mRNA. Neuropeptides, 38 (5), 316−324.
 
Mahlapuu, R.; Viht, K.; Balaspiri, L.; Bogdanovic, N.; Saar, K.; Soomets, U.; Land, T.; Zilmer, M.; Karelson, E.; Langel, U. (2003). Amyloid precursor protein carboxy-terminal fragments modulate G-proteins and adenylate cyclase activity in Alzheimer's disease brain. Molecular Brain Research, 117 (1), 73−82.
 
Adlerz, L.; Soomets, U.; Holmlund, L.; Viirlaid, S.; Langel, U.; Iverfeldt, K. (2003). Down-regulation of amyloid precursor protein by peptide nucleic acid oligomer in cultured rat primary neurons and astrocytes. Neuroscience Letters, 336 (1), 55−59.
 
Farquhar, M.; Soomets, U.; Bates, R.L.; Martin, A.; Langel, Ü.; Howl, J. (2002). Novel mastoparan analogs induce differential secretion from mast cells. Chemistry & Biology, 9 (1), 63−70.
 
Saar, K.; Mazarati, AM.; Mahlapuu, R.; Hallnemo, G.; Soomets, U.; Kilk, K.; Hellberg, S.; Pooga, M.; Tolf, BR.; Shi, TS.; Hokfelt, T.; Wasterlain, C.; Bartfai, T.; Langel, U. (2002). Anticonvulsant activity of a nonpeptide galanin receptor agonist. Proceedings of the National Academy of Sciences, 99 (10), 7136−7141.
 
Karelson, E.; Mahlapuu, R.; Zilmer, M.; Soomets, U.; Bogdanovic, N.; Langel, U. (2002). Possible signaling by glutathione and its novel analogue through potent stimulation of frontocortical G proteins in normal aging and in Alzheimer's disease. Annals of the New York Academy of Sciences, 973, 537−540.
 
Rezaei, K.; Xu, IS.; Wu, WP.; Shi, TJ.; Soomets, U.; Land, T.; Xu, XJ.; Wiesenfeld-Hallin, Z.; Hokfelt, T.; Bartfai, T.; Langel, U. (2001). Intrathecal administration of PNA targeting galanin receptor reduces galanin-mediated inhibitory effect in the rat spinal cord. Neuroreport, 12 (2), 317−320.
 
Rezaei, K.; Saar, K.; Soomets, U.; Valkna, A.; Nasman, J.; Zorko, M.; Akerman, K.; Schroeder, T.; Bartfai, T.; Langel, U. (2000). Role of third intracellular loop of galanin receptor type 1 in signal transduction. Neuropeptides, 34 (1), 25−31.
 
Lindgren, M.; Gallet, X.; Soomets, U.; Hallbrink, M.; Brakenhielm, E.; Pooga, M.; Brasseur, R.; Langel, U. (2000). Translocation properties of novel cell penetrating transportan and penetratin analogues. Bioconjugate Chemistry, 11 (5), 619−626.
 
Soomets, U.; Lindgren, M.; Gallet, X.; Hallbrink, M.; Elmquist, A.; Balaspiri, L.; Zorko, M.; Pooga, M.; Brasseur, R.; Langel, U. (2000). Deletion analogues of transportan. Biochimica et Biophysica Acta (BBA) - Biomembranes, 1467 (1), 165−176.
 
Hallbrink, M.; Saar, K.; Ostenson, CG.; Soomets, U.; Efendic, S.; Howl, J.; Wheatley, M.; Zorko, M.; Langel, U. (1999). Effects of vasopressin-mastoparan chimeric peptides on insulin release and G-protein activity. Regulatory Peptides, 82, 45−51.
 
Xu, ZQD.; Ma, XS.; Soomets, U.; Langel, U.; Hokfelt, T. (1999). Electrophysiological evidence for a hyperpolarizing, galanin (1-15)-selective receptor on hippocampal CA3 pyramidal neurons. Proceedings of the National Academy of Sciences of the United States of America, 96 (25), 14583−14587.
 
Soomets, U.; Mahlapuu, R.; Tehranian, R.; Jarvet, J.; Karelson, E.; Zilmer, M.; Iverfeldt, K.; Zorko, M.; Graslund, A.; Langel, U. (1999). Regulation of GTPase and adenylate cyclase activity by amyloid beta-peptide and its fragments in rat brain tissue. Brain Research, 850, 179−188.
 
Bavec, A.; Soomets, U.; Langel, U.; Zorko, M. (1998). Structural features of amphipathic peptides required for the activation of G-proteins. Acta Chimica Slovenica, 45 (1), 27−34.
 
Mazarati, AM.; Liu, HT.; Soomets, U.; Sankar, R.; Shin, D.; Katsumori, H.; Langel, U.; Wasterlain, CG. (1998). Galanin modulation of seizures and seizure modulation of hippocampal galanin in animal models of status epilepticus. Journal of Neuroscience, 18 (23), 10070−10077.
 
Poyner, DR.; Soomets, U.; Howitt, SG.; Langel, U. (1998). Structural determinants for binding to CGRP receptors expressed by human SK-N-MC and Col 29 cells: studies with chimeric and other peptides. British Journal of Pharmacology, 124 (8), 1659−1666.
 
Pooga, M.; Soomets, U.; Hallbrink, M.; Valkna, A.; Saar, K.; Rezaei, K.; Kahl, U.; Hao, JX.; Xu, XJ.; Wiesenfeld-Hallin, Z.; Hokfelt, T.; Bartfai, A.; Langel, U. (1998). Cell penetrating PNA constructs regulate galanin receptor levels and modify pain transmission in vivo. Nature Biotechnology, 16 (9), 857−861.
 
Soomets, U.; Kairane, C.; Zilmer, M.; Langel, U. (1997). Attempt to solubilize Na+/K+-exchanging ATPase with amphiphilic peptide PD1. Acta Chemica Scandinavica, 51 (3), 403−406.
 
Saar, K.; Valkna, A.; Soomets, U.; Rezaei, K.; Zorko, M.; Zilmer, M.; Langel, U. (1997). Role of the third cytoplasmic loop in signal transduction by galanin receptors. Biochemical Society Transactions, 25 (3), 1036−1040.
 
Maeorg, U.; Soomets, U.; Perkson, A.; Linask, K.; Raidaru, G. (1994). Synthesis of 4,4'-dibromobenzilic acid. Mendeleev Communications, 3, 99−100.
 
Soomets, UV.; Palumaa, PJ.; Yarv, JL. (1987). Mechanism of reaction of n,n-dimethyl-2-phenyl-aziridinium ion in acetylcholinesterase active-center. Bioorganicheskaya Khimiya, 13 (2), 198−203.
 
Palumaa, P.; Soomets, U.; Jarv, J. (1985). Effects of reaction medium and temperature on solvolysis of n,n-dimethyl-2-phenylaziridinium ion. Organic Reactivity, 22 (2), 238−257.
1.2. Teadusartiklid teistes rahvusvahelistes teadusajakirjades, millel on registreeritud kood, rahvusvaheline toimetus, rahvusvahelise kolleegiumiga eelretsenseerimine, rahvusvaheline levik ning kättesaadavus ja avatus kaastöödele
 
Lill, M.; Kõks, S.; Soomets, U.; Schalkwyk, LC.; Fernandes, C.; Lutsar, I.; Taba, P. (2013). Peripheral blood RNA gene expression profiling in patients with bacterial meningitis. Frontiers in Neuroscience, 7, 33.10.3389/fnins.2013.00033.
 
Kairane, C.; Mahlapuu, R.; Ehrlich, K.; Kilk, K.; Zilmer, M.; Soomets, U. (2012). Diverse effects of glutathione and UPF peptides on antioxidant defense system in human erythroleukemia cells K562. International Journal of Peptides, 2012, Article ID 124163. DOI: 10.1155/2012/124163.
 
Zilmer, M.; Soomets, U.; Rehema, A.; Langel, Ü. (2005). The glutathione system as an attractive therapeutic target. Drug Design Reviews - Online, 2 (2), 121−127.
 
Soomets, U.; Zilmer, M.; Langel, Ü. (2005). Manual solid-phase synthesis of glutathione analogs: a laboratory-based short course. Methods in Molecular Biology, 298, 241−257.
 
Soomets, U.; Hälbrink, M; Langel, Ü. (1999). Antisence properties of peptide nucleic acids. Frontiers in Bioscience (FBS), 4, D782−D786.
 
Longland, C.; Mezna, M.; Langel, Ü.; Hällbrink, M.; Soomets, U.; Wheatley, M.; Michelangeli, F.; Howl, J. (1998). Biochemical mechanisms of calcium mobilisation induced by mastoparan and chimeric hormone-mastoparan constructs. Cell Calcium, 24 (1), 27−34.
 
Soomets, U.; Hällbrink, M.; Zorko, M.; Langel, Ü. (1997). From galanin and mastoparan to galparan and transportan. Current Topics in Peptide and Protein Research, 2, 83−113.
 
Soomets, U.; Perkson, A. (1990). Synthesis of derivatives of benzilic acid - ligands of muscarinic receptor (in Russian). Experimental Biology, 2, 156−157.
1.3. Eelretsenseeritud teadusartiklid Eesti ja teiste riikide eelretsenseeritavates teadusajakirjades, millel on kohalik toimetuskolleegium, või eelretsenseeritud teadusartiklid Eesti kultuurile olulistes ajakirjades või teadusartiklid ajakirjades Akadeemia, Looming ja Vikerkaar.
 
Aug, Argo; Luik, Katrina; Kilk, Kalle; Soomets, Ursel; Kivastik, Jana; Kingisepp, Peet-Henn; Altraja, Alan (2011). Muutused väljahingatud õhu kondensaadis astma ja kroonilise obstruktiivse kopsuhaiguse korral. Eesti Arst, 459−465.
 
Joost, K.; Kilk, K.; Toome, L.; Soomets, U.; Õunap, K.; Žordania, R. (2008). Pika ahelaga rasvhapete oksüdatsiooni defekt imikul : haigusjuhu kirjeldus. Eesti Arst, 4, 274−279.
 
Soomets, U.; Mahlapuu, R.; Zilmer, M. (2002). Molekulaartehnoloogia praktilise meditsiini teenistuses: antisense tehnika. Eesti Arst, 81 (4), 245−250.
2.2. Monograafiad (sisestatud enne 1. juulit 2014. a.)
 
Soomets, U; Starkopf, J; Zilmer, Mihkel; Karelson, Ello-Rahel; Vihalemm, Tiiu; Zilmer, K; Valkna, A; Sillard, R; Langel, Ü (1996). Bioorganic chemistry for medical students. Tartu: Tartu University.
2.3. Dissertatsioonide seerias ilmunud dissertatsioonid (v.a. käsikirjalised);
 
Soomets, U. (2000). Development of novel transport peptides and their application in antisense techniques. (Doktoritöö, Stockholms universitet). Stockholm: Department of Neurochemistry and Neurotoxicology, Arrhenius Laboratories for Natural Sciences.
2.4. Kõrgkooliõpikud
 
Zilmer, M.;Soomets, U.; Rehema, A.; Altraja, S.; Mahlapuu, R.; Porosk, R.; Zilmer, K.; Kullisaar, T.; Kilk, K.; Kairane, C.; Salum, T. (2018). Inimkeha põhilised biomolekulid (meditsiiniliselt tähtsamad ülesanded). Avita.
3.1. Artiklid/peatükid lisas loetletud kirjastuste välja antud kogumikes (kaasa arvatud Web of Science Book Citation Index, Web of Science Conference Proceedings Citation Index, Scopus refereeritud kogumikud)
 
Ceslava Kairane, Riina Mahlapuu, Ülle Helena Meren, Kersti Zilmer, Ursel Soomets, Mihkel Zilmer (2014). Do Inhaled Glucocorticosteroids (In Vivo), Oral N-Acetylcysteine (In Vivo) and Glutathione (In Vitro) Affect Blood Redox Status in Chronic Obstructive Pulmonary Disease Patients? International Symposium on Medicinal Chemistry, Lisbon, Portugal September 7-11, 2014. Ed. Wiley Online Library. Wiley-V C H Verlag Gmbh, 163.
 
Jiang, Y.; Soomets, U.; Langel, Ü. (2006). Design and synthesis of CPPs. In: Langel, Ü (Ed.). Handbook of Cell-Penetrating Peptides, 2nd Edition (537−551).. CRC Press Inc.
 
Valkna, A.; Soomets, U.; Langel, Ü. (2002). Cell-penetrating peptides as vectors for delivery of nucleic acids. In: Langel, Ü. (Ed.). Cell Penetrating Peptides. Processes and Applications (347−363). . New York: CRC Press Inc.
 
Pooga, M.; Soomets, U.; Bartfai, T.; Langel, Ü. (2002). Synthesis of cell-Penetrating peptide-PNA constructs. In: Nielsen, P. (Ed.). Peptide nucleic acids: methods and protocols (225−236). . Totowa, NJ: Human Press. (Methods in molecular biology; 208).
 
Soomets, U.; Langel, Ü. (1999). Intracellular third loop of galanin receptor as G-protein interaction site. Peptides. Frontiers of Peptide Science: 15th American Peptide Symposium; Nashville, Tennessee; 14.-19.06.1997. Ed. Tam, J.P.; Kauyama, P.T.P. Dodrecht: Kluwer Academic Publishers, 662−663.
3.2. Artiklid/peatükid lisas mitte loetletud kirjastuste välja antud kogumikes
 
Kilk, K.; Terasmaa, A.; Soomets, U. (2008). Biochemistry of wolframin. In: Kõks, S.; Vasar, E. (Ed.). WFS1 Protein (Wolframin): Emerging Link Between the Emotional Brain and Endocrine Pancreas (87−106). . Fort P.O., Trivandrum-695 023, Kerala, India: Research Signpost.
 
Poyner, D.R.; Howitt, S.; Soomets, U.; Langel, Ü. (2000). Structure activity relationship for CGRP receptor ligands. In: Poyner, D.; Marshall, I.; Brain, S.D. (Ed.). The CGRP family: Calcitonin Gene-Related Peptide (Cgrp), Amylin, & Adrenomedullin (25−32).. Georgetown: Landes Bioscience.
 
Soomets, U.; Kilk, K.; Land, T.; Langel, Ü. (2000). Transportan, its analogues and their applications. Innovation and Perspectives in Solid Phase Synthesis and Combinatorial Libraries: Peptides, Proteins and Nucleic Acids. Proceedings of the 5th International Symposium, London. Ed. Epton, R. Kingswinford, England: Mayflower Worldwide, 131−136.
3.4. Artiklid/ettekanded, mis on avaldatud valdkonda 3.1. mittekuuluvates konverentsikogumikes
 
Ilves, Aire; Harzia, Hedi; Ling, Katri; Kaart, Tanel; Soomets, Ursel; Kilk, Kalle; Ots, Meelis (2013). Metabolomics as a novel tool for energy balance indication of dairy cows. 15th International Conference on Production Diseases in Farm Animals. Book of Abstracts.: ICPD 2013, Uppsala, Sweden, 24-28 June 2013. Ed. Göran Dalin. Swedish University of Agricultural Sciences, 137−137.
 
Ilves, Aire; Ling, Katri; Kilk, Kalle; Soomets, Ursel (2012). Changes in milk metabolome of dairy cows during the first months of lactation. Dairy production in modern loose housing cowsheds - practical implications and future challenges: NJF seminar 439. Dairy production in modern loose housing cowsheds - practical implications and future challenges. 2-4 May 2012, Tartu, Estonia. Ed. Kaasik, Allan. Tartu, Estonia, 29.
 
Ilves, Aire; Harzia, Hedi; Ling, Katri; Kärt, Olav; Soomets, Ursel; Kilk, Kalle (2011). Negative energy balance induced changes in milk metabolome of dairy cows. International Oskar Kellner Symposium. Metabolic Flexibility in Animal and Human Nutrition.: International Oskar Kellner Symposium. Metabolic Flexibility in Animal and Human Nutrition. Warnemünde, Germany, September 9-11, 2011. Ed. Cornelia C. Metges; Harald M. Hammon; Björn Kuhla; Monika Röntgen; Wolfgang B. Souffrant. Germany: Alstadt-Druck GmbH, 55−55.
 
Farquhar, M.; Soomets, U.; Brown, C.; Martin, A.; Bates, R.; Langel, Ü.; Howl, J. (2001). Venomous chimeric secretagogues. Peptides 2000: European Peptide Symposium; Montpellier, France; 10.-15.09.2000. Ed. Martinez, J.; Fehrentz, J.A. Paris: EDK, 633−634.
 
Brown, J.; Howl, J.; Martin, A.; Soomets, U.; Langel, Ü.; Brown, C. (2001). Single amino-acid substitutions in a mimetic tetradecapeptide agonist of the human P2Y2 receptor prevent second messenger activation. Peptides 2000: European Peptide Symposium; Montpellier, France; 10.-15.09.2000. Ed. Martinez, J.; Fehrentz, J.A. Paris: EDK, 913−914.
3.5. Artiklid/ettekanded, mis on avaldatud kohalikes konverentsikogumikes
 
Soomets, U; Ehrlich, K; Kullisaar, T; Mahlapuu, R; Pechter, Ü; Rosenberg, M; Sepp, K. (2008). Effect of novel antioxidant compound UPF on chronic kidney injury. Scand-Las and ICLAS Joint Meeting 2008 Abstract book: Scand-Las and ICLAS Joint Meeting 2008, 8-11 May, Tartu, Estonia. Tartu: Tartu University Press, 30.
5.1. Konverentsiteesid, mida kajastab Thomson Reuters Web of Science
 
Kairane, C; Mahlapuu, R; Porosk, R; Zilmer, M; Soomets, U. (2018). The effects of glutathione analogues on Na,K-ATPase activity in the kidneys of the wildtype and the Wfs1 gene mutated mice in vitro and in vivo. Journal of Peptide Science: 35th European Peptide Symposium, Dublin City University, Ireland, 26th - 31st August 2018. Wiley Online Library, 136.
 
Zagura, Maksim; Kals, Jaak; Paapstel, Kaido; Kilk, Kalle; Serg, Martin; Kampus, Priit; Eha, Jaan; Soomets, Ursel; Zilmer, Mihkel. (2015). Metabolomic characteristics of arterial stiffness in patients with peripheral arterial disease. Cardiology, 241: Nordic-Baltic Cardiology Congress, Tallinn, 4.06-6.06.2015. Karger, E150−E151.
 
Altraja, A.; Aug, A.; Kilk, K.; Mahlapuu, R.; Altraja, S.; Soomets, U. (2014). Phenotyping of chronic obstructive pulmonary disease by integrated metabolomic profiling of exhaled breath condensate. American Journal of Respiratory and Critical Care Medicine, 189, A5880.
 
Aug, A.; Altraja, S.; Kilk, K.; Mahlapuu, R.; Soomets, U.; Altraja, A. (2014). E-cigarettes profoundly affect metabolome of primary human bronchial epithelial cells. European Respiratory Journal, 44 (Suppl. 58), 1834.
 
Aug, A.; Altraja, S.; Kilk, K.; Laaniste, L.; Mahlapuu, R.; Soomets, U.; Altraja, A. (2013). Acute effect of cigarette smoke on human bronchial epithelial cell metabolome is reversible by UPF1. European Respiratory Journal, 42, 819s.
 
Kairane, C.; Mahlapuu, R.; Zilmer, M.; Soomets, U. (2012). The effects of bioactive thiols on the activity of CuZnSOD of the patiens with chronic obstructive pulmonary disease in vitro and in vivo. 279: 22nd IUBMB and 37th FEBS Congress, Seville, Spain September 4-9, 2012. The FEBS Journal, 210. (Suppl. 1).
 
Soomets, U.; Kingo, K.; Mahlapuu, R.; Koks, S. (2011). Antioxidants have possible therapeutic activity for psoriasis. 6th International Congress of Psoriasis - from Gene to Clinic. , E28−E28.
 
Altraja, S.; Soomets, U.; Mahlapuu, R.; Altraja, A. (2011). Differential regulation of glutamate-cysteine ligase subunits by 4-hydroxy-2-nonenal is balanced by an antioxidant tetrapeptide UPF1. American Journal of Respiratory and Critical Care Medicine, 183, A5965.
 
Asser, A.; Kõks, S.; Soomets, U.; Terasmaa, A.; Sauk, M.; Eltermaa, M.; Piip, P.; Taba, P. (2010). Acute effects of methcathinone and manganese in mice: a dose response study. Movement Disorders, 25, S226−S226.
 
Sikk, K.; Koks, S.; Soomets, U.; Schalkwyk, L.; Fernandes, C.; Haldre, S.; Aquilonius, SM.; Taba, P. (2010). Peripheral blood RNA gene expression profiling in illicit methcathinone users reveals effect on immune system. Movement Disorders, 25, S226−S226.
 
Altraja, S.; Mahlapuu, R.; Soomets, U.; Altraja, A. (2010). An antioxidant tetrapeptide UPF1 maintains glutathione level in normal human bronchial epithelial cells exposed to oxidative stress. American Journal of Respiratory and Critical Care Medicine, 181, A2686.
 
Altraja, S.; Mahlapuu, R.; Soomets, U.; Altraja, A. (2010). The effect of antioxidant tetrapeptide UPF1 on enzymes involved in glutathione metabolism in human bronchial epithelial cells exposed to oxidative stress. European Respiratory Journal, 36(Suppl.54), 438s.
 
Joost, K.; Kilk, K.; Soomets, U.; Õunap, K. (2009). Selective screening of fatty acid oxidation effects in Estonia: one year experience. Molecular Genetics and Metabolism: 11th International Congress of Inborn Errors of Metabolism; San Diego, USA; 29.08 - 2.09.2009. Elsevier, 56. (98).
 
Fisher, L.; Samuelsson, M.; Toro, V. C.; Soomets, U.; Yang, J.; Langel, Ü.; Iverfeldt, K. (2004). Downregulation of Abeta-induced cytokine expression in glial cells using NFkappaB decoy. Journal of Neuroimmunology, 154, 31−31.
 
Zilmer, M.; Soomets, U.; Karelson, E.; Mahlapuu, R.; Zilmer, K.; Langel, U. (2002). Glutathione-like peptide as an antioxidative protector molecule. Free Radical Biology and Medicine, 33, S216−S216.
5.2. Konverentsiteesid, mis ei kuulu valdkonda 5.1
 
Kairane, Ceslava; Mahlapuu, Riina; Porosk, Rando; Zilmer, Mihkel; Soomets, Ursel (2016). THE EFFECT OF GLUTATHIONE ANALOGUES UPF1 AND UPF17 ON NA,K-ATPASE ACTIVITY IN THE KIDNEYS OF C57BL/6 MICE IN VITRO AND IN VIVO. XXIV EFMC International Symposium on Medicinal Chemistry BOOK OF ABSTRACTS: XXIV EFMC International Symposium on Medicinal Chemistry UK Manchester from August 28 - September 1, 2016.. LD Organisation Scientific Conference Producers, Belgium, 140.
 
Altraja, A.; Aug, A.; Kilk, K.; Mahlapuu, R.; Altraja, S.; Soomets, U. (2015). Phenotyping of COPD by integrated metabolomic profiling of exhaled breath condensate and peripheral blood. European Respiratory Journal, 46 (Suppl.59), OA2922.
 
Taalberg, E.; Porosk, R.; Mahlapuu, R.; Soomets, U. (2015). Glutatiooni seleno- ja esteranaloogide disain, süntees ja omaduste uurimine. Eesti Arst, 40.
 
Porosk, R.; Mahlapuu, R.; Kairane, C.; Zilmer, M.; Soomets, U. (2015). DO NOVEL GSH ANALOGUES ALLEVIATE THE COMPLICATIONS OF DIABETES IN VIVO? JMMC - 2015 Abstracts: IX Joint Meeting on Medicinal Chemistry. June 7-10, 2015 Athens, Greece..
 
Zagura, Maksim; Kals, Jaak; Paapstel, Kaido; Kilk, Kalle; Serg, Martin; Kampus, Priit; Eha, Jaan; Soomets, Ursel; Zilmer, Mihkel. (2014). Metabolomic Signature of Arterial Stiffness in Patients with Peripheral Arterial Disease. Final Programme and Abstracts: Rahvusvaheline kongress: Artery 14, 9.-11. oktoober 2014 Maastricht, Holland. , 8.
 
Zagura, Maksim; Kals, Jaak; Paapstel, Kaido; Kilk, Kalle; Serg, Martin; Kampus, Priit; Eha, Jaan; Soomets, Ursel; Zilmer, Mihkel. (2014). Arterite jäikuse metaboloomiline profiil alajäsemete arterite ateroskleroosiga patsientidel. Eesti Arst. , 31.
 
Kairane, C.; Mahlapuu, R.; Hansen, M.; Soomets, U.; Zilmer, M. (2013). The significance of the configuration of peptides on their biological activities. VIIIth Joint Meeting on Medicinal Chemistry, June 30-July 4 2013, Lublin. P-18.
 
Antoniak, KM; Kairane, C; Mahlapuu, R; Zilmer, M; Soomets, U. (2013). Glutatiooni analoogi UPF17 mõju in vivo NaK-ATPaasi aktiivsusele tervete ja Wsf1 geenimutatsiooniga hiirte neerudes. Eesti Arst, 92 (Lisa2): Tartu Ülikooli arstiteatuskonna aastapäeva teaduskonverents 2013. 31.
 
Porosk, R; Kilk, K; Mahlapuu, R; Soomets, U. (2013). Wfs1 geeni defektiga hiire metaboloomi kirjeldus. Eesti Arst, 92 (Lisa2): Tartu Ülikooli arstiteaduskonna aastapäeva teaduskonverents 2013. , 30.
 
Oit, I.; Soomets, U.; Altraja, A. (2013). Glutathione antioxidant system – a defense mechanism in COPD. Proceedings of the 12th International Conference on Oxidative Stress, Redox States and Antioxidants/15th Anniversary of ISANH, Paris, 3-4 July 2013.
 
Aug, A.; Altraja, S.; Kilk, K.; Laaniste, L.; Mahlapuu, R.; Soomets, U.; Altraja, A. (2012). Antioxidant tetrapeptide UPF1 exerts an immediate effect on cigarette smoke-altered metabolic state of human bronchial epithelial cells. European Respiratory Journal, 40, 837s.
 
Altraja, S.; Mahlapuu, R.; Soomets, U.; Altraja, A. (2012). The effect of an antioxidant tetrapeptide UPF1 on glutathione metabolism in human bronchial epithelial cells exposed to cigarette smoke. American Journal of Respiratory and Critical Care Medicine, 185, A1256.
 
Harzia, Hedi; Kilk, Kalle; Jõudu, Ivi; Henno, Merike; Kärt, Olav; Soomets, Ursel (2012). Metabolome of non- and coagulating cows milk. Book of abstracts ESR workshop "Feed your knowledge!", 7-8 June 2012, Barcelona, Spain: Feed your knowledge! workshop, 7-8 June 2012, Barcelona, Spain. Ed. Tres, Alba; Altintzoglou,Themistokilis; Livingstone, Katherine; Frankic, Tamara; Pinotti, Luciano; D., 44.
 
Harzia, Hedi; Kilk, Kalle; Jõudu, Ivi; Henno, Merike; Kärt, Olav; Soomets, Ursel (2012). Metabolic profiles of non- and coagulating bovine milk. Dairy production in modern loose housing cowsheds - practical implications and future challenges: NJF seminar 439. Dairy production in modern loose housing cowsheds - practical implications and future challenges. 2-4 May 2012, Tartu, Estonia. Ed. Kaasik, Allan. Tartu, Estonia, 44−45.
 
Kase, G.; Kairane, C.; Mahlapuu, R.; Soomets, U. (2012). The effect of GSH analogues UPF6 and UPF19 on the glutathione levels and GSSG/GSH ratio in the mouse liver. International Pharmacy Graduation Projects Symposium 15-16 June Haziran 2012. Near East University Faculty of Pharmacy, 38.
 
Siitas, M.; Kairane, C.; Mahlapuu, R.; Soomets, U.; Zilmer, M. (2012). GSH analoogi UPF17 mõju in vivo GSH redoksstaatusele metsikut tüüpi ja Wfs1 geenmutatsiooniga hiirte maksas. 91: Tartu Ülikooli Arstiteaduskonna aastapäeva teaduskonverents 2012. Eesti Arst, 34.
 
Kase, G.; Kairane, C.; mahlapuu, R.; Soomets, U.; Zilmer, M. (2012). Glutatiooni analoogide UPF6 ja UPF19 in vivo mõju glutatiooni tasemele ja redokssuhtele hiire maksas. 91: Tartu Ülikooli Arstiteaduskonna aastapäeva teaduskonverents 2012. Eesti Arst , 33.
 
Oit, I.; Virág, L.; Soomets, U.; Altraja, A. (2012). COPD as a systemic disease. Proceedings of the FEBS 3+ Meeting, 283.
 
Kairane, C.; Mahlapuu, R.;Soomets, U.; Zilmer, M. (2011). The effect of glutathione and its analogue UPF17 on activity of frontal cortical Na,K-ATPase of Alzheimer`s disease in vitro. Amino Acids, 41 (1), 47−48.
 
Joost, K; Kahre, T; Kilk, K; Uudelepp, M-L; Soomets, U; Õunap, K. (2010). Pika ahelaga hüdroksü-atsüül CoA dehüdrogenaasi defitsiidi esinemine Eestis. Eesti Arst, 98: Eesti Arstiteaduskonna Päevad, Tartu, oktoober 2010. , 563. (9).
 
Lill, M.; Kõks, S.; Soomets, U.; Schalkwyk, LC.; Fernandes, C.; Lutsar, I., Taba, P. (2010). Peripheral blood RNA gene expression profiling in the patients with community-acquired bacterial meningitis. In: (x).20th European Congress of Clinical Microbiology and Infectious Diseases, Vienna, Austria, 10 - 13 April.
 
Kivastik, J.; Kingisepp, PH.; Kilk, K.; Soomets, U.; Aug, A.; Luik, K.; Altraja, A. (2010). Changes in exhaled breath condensate in asthma and COPD: a full analysis of mass spectra. European Respiratory Journal, 36(Suppl. 54), 227s.
 
Oit, I.; Hansen, M.; Soomets, U.; Altraja, A. (2010). Põletiku ja oksüdatiivse stressiga seotud ensümaatiliste markerite geeniekspressiooni muutused KOK-haigetel sõltuvalt haiguse raskusastmest. Uute antioksüdantsete peptiidide mõju. Eesti Arst, 89 (9), 584−584.
 
Kairane, C.; Mahlapuu, R.; Ehrlich, K.; Soomets, U.; Zilmer, M. (2010). The significance of structural modifications of UPF peptides , glutathione analogues, on CuZnSOD activity of K562 cells. 18th European Symposium on Quantitative Structure-Activity Relationships; Rhodes, Greece; 19-24 September 2010. 267.
 
Mahlapuu, R.; Vaher, M.; Ida, K.; Soomets, U. (2010). Glutatiooni analoogide mõju raku redokstsükli ensüümide aktiivsusele. XXXI Eesti Keemiapäevad, Tallinn 2010. , 52.
 
Kilk, K., Mahlapuu, R., Viirlaid, S., Järv, J., Soomets, U. (2009). Identification of pharmacophores in antioxidative UPF peptides. European Journal of Pharmaceutical Sciences, 38: 3rd BBBB-Bosphorus International Conference on Pharmaceutical Sciences; Antalya, Turkey; 26-28.10.2009. Elsevier Science BV, 157−158. (1).
 
Oit, I., Mahlapuu, R., Raud, K., Kingo, K., Soomets, U. (2009). Effects of novel glutathione analogues on the expression of antioxidative enzymes. Abstract Book and Program: 5th Conference on Separation and Related Techniques by Nordic Separation Sciemce Society; Tallinn, Estonia; 26-29.08.2009. Ed. Borissova, M., Vaher, M. Infotrükk OÜ, 122.
 
Kairane, C.; Mahlapuu, R.; Tarros, K.; Soomets, U.; Zilmer, M. (2009). Differential regulation of CuZn-superoxide dismutase activity in K562 cells by glutathione and its synthetic analogue alpha-glutathione. 45th International Conference on Medicinal Chemistry; University Orleans, France; July 1-3, 2009. 86.
 
Mahlapuu, R.; Vaher, M;. Ida, K.; Viirlaid, S.; Kaljurand, M.; Soomets, U. (2009). Dimerisation of glutathione analogues in the presence of cellular redox cycle enzymes. Abstract Book and Program: 5th Conference on Separation and Related Techniques by Nordic Science Society. Toim. Maria Borissova, Merike Vaher. Tallinn University of Technology Press, 112.
 
Kilk, K.; Mahlapuu, R.; Viirlaid, S.; Järv, J.;Soomets, U. (2009). Pharmacophores in antioxidative UPF peptides. European Journal of Pharmaceutical Sciences, 38 (1), 157.
 
Tõnisson, N.; Laidre, P.; Ilisson, P.; Ilus, T.; Tammur, P.; Kuuse, K.; Kruustük, K.; Teek, R.; Joost, K.; Soomets, U.; Sitska, M.; Muru, K.; Kerna, I.; Kahre, T.; Reimand, T.; Õunap, K. (2009). Kliinik 2009 [Videosalvestis] : uusi diagnostikavõimalusi kliinilises geneetikas. Kliinik 2009, Tartu Ülikooli Kliinikumi täienduskonverents(2009 :Tartu). Tartu: TÜ IT Multimeedia talitus.
 
Kõks, S.; Velthut, A.; Sarapik, A.; Reinmaa, E.; Soomets, U.; Jaakma, Ü.; Salumets, A. (2008). Folliikuli granuloosa rakkude funktsionaalne diferentseerumine: transkriptoomi uuringud. Eesti Arst, 9. , 688−689.
 
Oit, I.; Mahlapuu, R.; Raud, K.; Kingo, K.; Soomets, U. (2008). Glutatiooni analoogide mõju psoriaasihaigete mõningate antioksüdantsete ensüümide ekspressioonile. Eesti Arst 87(9): TÜ Arstiteaduskonna päevad; Tartu; 9. oktoober 2008. , 670.
 
Mahlapuu, R.; Viirlaid, S.; Ehrlich, K.; Saar, K.; Soomets, U. (2007). Novel tetrapeptidic glutathione analogues: chemical activity in vitro. Abstracts of Scientific Conference: 30th Estonian Chemistry Days. , 86−87.
 
Ehrlich, K.; Viirlaid, S.; Mahlapuu, R.; Saar, K.; Zilmer, M.; Soomets, U. (2007). UPF peptiidid, antioksüdasntsed glutatiooni analoogid - disain, vabade radikaalide eliminatsioon in vitro ja toksilisus K562 rakkudele. Eesti Arst, 86 (9), 705.
 
Mahlapuu, R.; Ehrlich, K.; Kairane, C.; Soomets, U. (2007). Novel UPF analogues affect glutathione peroxidase and glutathione reductase activity. Farmacevtski vestnik: 5th Joint Meeting on Medicinal Chemistry, June 14-21, 2007, Portorož, Slovenia. 135 .
 
Ehrlich, K.; Viirlaid, S.; Mahlapuu, R.; Saar, K.; Zilmer, M.; Soomets, U. (2007). UPF peptides, antioxidative glutathione analogues – design, free radical scavenging in vitro and toxicity to K562 cells. Free Radical Research, 41: European Meeting of the Society for Free Radical Research; 10-13 October; Vilamoura, Portugal. Free Radical Research, 25. (1).
 
Ehrlich, Kersti; Mahlapuu, Riina; Zilmer, Mihkel; Soomets, Ursel (2006). Sünteetilised glutatsiooni analoogid kui võimalikud neutrofiilide NAD(P)H oksüdaasi poolt produtseeritud superoksiidi radikaali elimineerijad. Eesti Arst, 9, 616.
 
Vaher, M.; Mahlapuu, R.; Ebber, A.; Soomets, U.; Kaljurand, M. (2006). Monitoring the oxidation of the gluthatione and related neuropeptides by capillary electrophoresis. Abstractbook of 10th Naples workshop on bioactiv peptides: 10th naples workshop on bioactive peptides Naples 11-14 June 2006. , 142−143.
 
Raud, K.; Kingo, K.; Ehrlich, K.; Kõks, S.; Silm, H.; Vasar, E.; Soomets, U. (2006). Glutatsioonisüsteemi regulatsioon psoriaasi korral. Eesti Arst, 85 (9): Arstiteaduskonna päevad 2006. , 633−634.
 
Ehrlich, K.; Mahlapuu, R.; Viirlaid, S.; Zilmer, M.; Langel, Ü.; Soomets, U. (2005). Antioxidative properties of novel antioxidant UPF1 and its analogues. 1st BBBB Conference on Pharmaceutical Sciences, Siofok, Hungary,September 26-28. , 132−133.
 
Pruler, T.; Pulges, K.; Hallaste, M.; Kals, J.; Soomets, U.; Starkopf, J.; Pulges, A.; Zilmer, M. (2004). Antioksüdant UPF-1 parandab isheemiajärgset kontraktiilset funktsiooni isoleeritud rotisüdametel. Eesti Arst, 83 (9), 634.
 
Põder, P.; Kals, J.; Talonpoika, A.; Soomets, U.; Starkopf, J.; Arend, A.; Pulges, A.; Zilmer, M. (2001). Peptiid UPF 1 kaitseb roti aju isheemilise kahjustuse eest. Eesti Arst, 80 (9), 415.
 
Soomets, U.; Kilk, K.; Mahlapuu, R.; Zilmer, M. (2000). Peptiidsete nukleiinhapete ja uute transport-peptiidide kasutamine antisense tehnikas. Eesti Arst, 79 (9), 568.
6.2. Õpikud ja muud õppeotstarbelised publikatsioonid, v.a. kõrgkooliõpikud;
 
Porosk, R.; Kilk, Kalle.; Mahlapuu, R.; Soomets, U. (2018). Bioorgaanilise keemia põhimõisted.
 
Soomets, U.; Kilk, K.;Ottas, A.; Porosk, R.; Mahlapuu, R.; Zilmer, M. (2018). Inimese ainevahetusega seotud metaboliitide struktuur, reaktsioonivõime ja biofunktsioonid. Biokeemia I osa.
 
Soomets, U.; Zilmer, M.; Starkopf, J.; Karelson, E.-R.; Vihalemm, T.; Zilmer, K.; Sillard, R.; Bourne, J; Langel, Ü. (1999). Selected knowledge for medical biochemistry. Tartu: Tartu Ülikooli Kirjastus.
 
Karelson, E.; Soomets, U.; Zilmer, M.; Vihalemm, T.; Zilmer, K. (1998). Valitud peatükid meditsiinilise biokeemia jaoks. Tartu: Tartu University Press.
 
Soomets, U.; Karlström, A.; Zilmer, M.; Langel, Ü. (1998). Solid phase peptide synthesis of glutathione and its analogs by Fmoc- and tert-Boc-chemistry. Manual for laboratory course. Tartu: Tartu University Press.
 
Soomets, U.; Zilmer, M.; Karelson, E.-R.; Vihalemm, T.; Valkna, A.; Zilmer, K. (1995). Bioorgaaniline keemia arstiteaduskonna üliõpilastele. Tartu: Tartu Ülikool.
6.3. Populaarteaduslikud artiklid;
 
Pooga, M.; Langel, Ü.; Hansen, M., Soomets, U.; Kilk, K. (2009). Rakusisesed märklauad. Villems, R. (Toim.). Eesti Vabariigi Teaduspreemiad (72−85). . Tallinn: Eesti Teaduste Akadeemia.
6.6. Muudes ajakirjades ja ajalehtedes avaldatud artiklid;
 
Mahlapuu, R., Soomets, U., Zilmer, M., Langel, Ü. (2004). Alzheimeri tõve molekulaarsed alused: osalevad valgud ja peptiidid: uued ravistrateegiad. Lege Artis, 8 (32), 10−14.
6.7. Muu loome
 
Soomets, U. (1994). 4,4' -dibromobensiilhappe ja selle derivaatide süntees. (Magistritöö, Tartu Ülikool). Tartu: Tartu Ülikool.

Tööstusomand

18.01.2022

Ursel Soomets

https://www.etis.ee/CV/Ursel_Soomets/eng
18.07.1962
15.01.2022

Career

Institutions and positions
01.01.2021–15.01.2022   
University of Tartu, Faculty of Medicine, Institute of Biomedicine and Translational Medicine, Professor of Medical Metabolomics (1,00)
01.02.2020–31.12.2020   
University of Tartu, Faculty of Medicine, Institute of Biomedicine and Translational Medicine, Professor of Medical Metabolomics (0,60)
01.02.2020–31.12.2020   
University of Tartu, Faculty of Medicine, Institute of Biomedicine and Translational Medicine, Senior Research Fellow in General Biochemistry (0,40)
01.01.2016–31.01.2020   
University of Tartu, Faculty of Medicine, Institute of Biomedicine and Translational Medicine, Professor of Medical Metabolomics (0,50)
01.01.2016–31.01.2020   
University of Tartu, Faculty of Medicine, Institute of Biomedicine and Translational Medicine, Senior Research Fellow in General Biochemistry (0,50)
01.02.2015–31.12.2015   
University of Tartu, Faculty of Medicine, Institute of Biomedicine, Professor of Medical Metabolomics (0,50)
01.02.2015–31.12.2015   
University of Tartu, Faculty of Medicine, Institute of Biomedicine, Senior Research Fellow in General Biochemistry (0,50)
21.05.2013–31.01.2015   
University of Tartu, Faculty of Medicine, Institute of Biomedicine, Professor of Medical Metabolomics (0,50)
21.05.2013–31.01.2015   
University of Tartu, Faculty of Medicine, Institute of Biomedicine, Senior Research Fellow in General Biochemistry (0,50)
01.02.2010–20.05.2013   
University of Tartu, Faculty of Medicine, Department of Biochemistry, Senior Research Fellow in General Biochemistry (0,50)
01.02.2010–20.05.2013   
University of Tartu, Faculty of Medicine, Department of Biochemistry, Professor of Medical Metabolomics (0,50)
01.02.2010–21.01.2015   
University of Tartu, Faculty of Medicine, Dean's Office, Programme Director
01.01.2008–31.12.2013   
Institute of Psychiatry, King's College, University of London, visiting lecturer
22.07.2006–21.12.2006   
University of Tartu, Faculty of Medicine, Centre of Molecular and Clinical Medicine, Senior Research Fellow extraordinarius (1,00)
01.02.2005–31.01.2010   
University of Tartu, Faculty of Medicine, Department of Biochemistry, Associate Professor (0,50)
01.02.2005–31.01.2010   
University of Tartu, Faculty of Medicine, Department of Biochemistry, Senior Research Fellow (0,50)
01.05.2000–31.01.2005   
University of Tartu, Faculty of Medicine, Department of Biochemistry, Associate Professor (0,50)
01.05.2000–31.01.2005   
University of Tartu, Faculty of Medicine, Department of Biochemistry, Senior Research Fellow (0,50)
01.01.2000–31.12.2005   
University of Tartu, Medical Faculty, Dept of Biochemistry, associate professor (1/2), senior researcher (1/2), Department of Biochemistry, University of Tartu
01.01.1991–31.12.1991   
senior engineer, Laboratory of Enzymology, University of Tartu
01.01.1991–31.12.2000   
senior lecturer, Department of Biochemistry, Faculty of Medicine, University of Tartu
01.01.1987–31.12.1990   
post-graduate studentship, Department of Organic Chemistry, University of Tartu
01.01.1987–31.12.1987   
engineer, Laboratory of Bioorganic Chemistry, University of Tartu
01.01.1985–31.12.1987   
research fellow, department of Organic Chemistry, University of Tartu
 
 
Education
1998–2000   
Doctoral studies in Department of Neurochemistry and Neurotoxicology, Stockholm University
1996–2000   
Doctoral studies in Department of Biochemistry, Faculty of Medicine, University of Tartu
1980–1985   
Faculty of Physics and Chemistry, University of Tartu, chemist (bio-organic- and biochemistry)
 
 
R&D related managerial and administrative work
2013−...   
Member of the Board of the Institute of Biomedicine and Translational Medicine, University of Tartu
2013−...   
Assessor of the Estonian Accreditation Center
2005−...   
Member of the Board of Neurosciences (PhD program)
2011−2016   
Executive Director of the Center for Translational Genomics (CTG) of Tartu University
2010−2015   
Member of the Board of the Estonian Biochemical Society
2008−2015   
Member of the Board of the Centre of excellence for translational medicine
2008−2014   
Head of the Board of the biomedical sciences (Masters Degree program) of Medical Faculty
2003−2011   
member of Estonian Science Foundation Expert Comission for Health

Qualifications

Academic degrees
Ursel Soomets, Doctor's Degree, 2000, (sup) Ülo Langel; Mihkel Zilmer, Development of novel transport peptides and their application in antisense techniques, University of Stockholm.
Ursel Soomets, Research Master's Degree, 1994, (sup) Uno Mäeorg, Synthesis of 4,4'-dibromobenzilic acid and its derivatives (Synthesis of 4,4'-dibromobenzilic acid and its derivatives), University of Tartu.
 
 
Honours & awards
2012, Ursel Soomets, Small Medal of University of Tartu
2010, Ursel Soomets, The Science Award of the Tartu University Hospital (together with K. Joost, T. Kahre, K. Kilk, M.-L. Uudelepp, K. Õunap)
2009, Ursel Soomets, The National Science Award of the Republic of Estonia in chemistry and molecular biology (together with Ü. Langel, M. Pooga, K. Kilk and M. Hansen)
2008, Ursel Soomets, University of Tartu Badge of Distinction
 
 
Fields of research
ETIS CLASSIFICATION: 3. Health; 3.1. Biomedicine; CERCS CLASSIFICATION: B470 Physiology ; SPECIFICATION: Design and synthesis of antioxidative peptides, studies of their biological activity with techniques of peptidomics and metabolomics.Other fields of interest are: peptide and peptide nucleic acid synthesis, design and synthesis of bioactive antioxidative nonpeptidic compounds, studies of the mechanisms of psoriasis and neurodegenerative diseases.
 
 
Additional information
Member of American Peptide Society, member of Estonian Biochemical Society.
I participate in the following international collaborations of our group: with Stockholm University, London King's College, Ljubljana University (Slovenija), SCRIPPS institute (USA), University of Wolverhampton;
- in Estonia: Esonian Biocenter, Tallinn University of Technology, Institute of Developmental Biology, TU Institute of Physiology, Tallinn Children's Hospital, Department of Pediatrics of TU, Medical GeneticsCenter, United Laboratories of TU Hospital

Completed projects

Dissertations under supervision

Supervised dissertations

Publications

1.1. Teadusartiklid, mis on kajastatud Web of Science andmebaasides Science Citation Index Expanded, Social Sciences Citation Index, Arts & Humanities Citation Index, Emerging Sources Citation Index ja/või andmebaasis Scopus (v.a. kogumikud)
 
Ilves, Liis; Ottas, Aigar; Kaldvee, Bret; Abram, Kristi; Soomets, Ursel; Zilmer, Mihkel; Reemann, Paula; Jaks, Viljar; Kingo, Külli (2021). The metabolomic analysis of skin biopsies from atopic dermatitis patients reveals hallmarks of inflammation, disrupted barrier function and oxidative stress. Acta Dermato Venereologica, 101 (2). DOI: /doi.org/10.2340/00015555-3766.
 
Kairane, C.; Mahlapuu, R.; Porosk, R.; Zilmer, M.; Soomets, U. (2019). The effects of glutathione analogues on Na,K-ATPase activity in the kidneys of the wildtype and the Wfs1 gene mutated mice in vitro and in vivo. Journal of Peptide Science, 223−225. DOI: 10.17952/35EPS.2018.223.
 
Nõmm, Monika; Porosk, Rando; Pärn, Pille; Kilk, Kalle; Soomets, Ursel; Kõks, Sulev; Jaakma, Ülle (2019). Invitro culture and non-invasive metabolic profiling of single bovine embryos. Reproduction Fertility and Development, 31 (2), 306−314. DOI: 10.1071/RD17446.
 
Hansen, Mats; Porosk, Rando; Mahlapuu, Riina; Kairane, Ceslava; Kilk, Kalle; Soomets, Ursel (2019). GSH Synthetic Analogue O-Methyl-L-Tyrosinylglutathione Regulates Nrf2-Mediated Expression of GCLc and GCLm. Journal of Chemistry, ARTN 3841219. DOI: 10.1155/2019/3841219.
 
Ottas, Aigar; Fishman, Dmytro; Okas, Tiia-Linda; Kingo, Külli; Soomets, Ursel; (2017).

The metabolic analysis of psoriasis identifies the associated metabolites while providing computational models for the monitoring of the disease

. Archives of Dermatological Research, 309 (7), 519−528. DOI: 10.1007/s00403-017-1760-1.
 
Porosk, R.; Mahlapuu, R.; Terasmaa, A.; Kilk, K.; Soomets, U. (2017). Glutathione system in Wolfram syndrome 1‑deficient mice. Molecular Medicine Reports, 7092−7097. DOI: 10.3892/mmr.2017.7419.
 
Porosk, R.; Terasmaa, A.; Mahlapuu, R.; Soomets, U.; Kilk, K. (2017). Metabolomics of the Wolfram Syndrome 1 Gene (Wfs1) Deficient Mice. OMICS A Journal of Integrative Biology, 21 (2), 721−732. DOI: 10.1089/omi.2017.0143.
 
Ottas, Aigar; Fishman, Dmytro; Okas, Tiia-Linda; Pussa, Tonu; Toomik, Peeter; Martson, Aare; Kingo, Kulli; Soomets, Ursel (2017).

Blood serum metabolome of atopic dermatitis: Altered energy cycle and the markers of systemic inflammation

. PLoS ONE, 12 (11), ARTN e0188580. DOI: 10.1371/journal.pone.0188580.
 
Kriisa, Kärt; Leppik, Liisa; Balõtšev, Roman; Ottas, Aigar; Soomets, Ursel; Koido, Kati; Volke, Vallo; Innos, Jürgen; Haring, Liina; Vasar, Eero; Zilmer, Mihkel (2017). Profiling of Acylcarnitines in First Episode Psychosis before and after Antipsychotic Treatment. Journal of Proteome Research, 16 (10), 3558−3566. DOI: 10.1021/acs.jproteome.7b00279.
 
Asser, Andres; Kõks, Sulev; Snellman, Anniina; Haaparanta-Solin, Merja; Arponen, Eveliina; Grönroos, Tove; Nairismägi, Jaak; Bergquist, Jonas; Soomets, Ursel; Piip, Piret; Eltermaa, Mall; Sauk, Martin; Lindmäe, Hanna; Rinne, Juha O; Taba, Pille (2016). Increased striatal VMAT2 binding in mice after chronic administration of methcathinone and manganese. Brain Research, 1652, 97−102. DOI: 10.1016/j.brainres.2016.09.034.
 
Kazarjan, J.; Mahlapuu, R.; Hansen, M.; Soomets, U.; Kaljurand, M.; Vaher, M. (2015). Investigation of the surfactant type and concentration effect on the retention factors of glutathione and its analogues by micellar electrokinetic chromatography. Journal of Separation Science, 38 (19), 3461−3468. DOI: 10.1002/jssc.201500567.
 
Zagura, Maksim; Kals, Jaak; Kilk, Kalle; Serg, Martin; Kampus, Priit; Eha, Jaan; Soomets, Ursel; Zilmer, Mihkel. (2015). Metabolomic signature of arterial stiffness in male patients with peripheral arterial disease. Hypertension Research, 38 (12), 840−846.
 
Kilk, Kalle; Meitern, Richard; Härmson, Oliver; Soomets, Ursel; Hõrak, Peeter (2014). Assessment of oxidative stress in serum by d-ROMs test. Free Radical Research, 48 (8), 883−889. DOI: 10.3109/10715762.2014.919390.
 
Aug, A.; Altraja, A.; Altraja, S.; Laaniste, L.; Mahlapuu, R.; Soomets, U.; Kilk, K. (2014). Alterations of bronchial epithelial metabolome by cigarette smoke are reversible by an antioxidant, O-methyl-L-tyrosinyl-γ-L-glutamyl-L-cysteinylglycine. American Journal of Respiratory Cell and Molecular Biology, 51 (4), 586−594. DOI: 10.1165/rcmb.2013-0377OC.
 
Punapart, Marite; Eltermaa, Mall; Oflijan, Julia; Sütt, Silva; Must, Anne; Kõks, Sulev; Schalkwyk, Leonard C.; Fernandes, Catherine; Vasar, Eero; Soomets, Ursel; Terasmaa, Anton (2014). Effect of Chronic Valproic Acid Treatment on Hepatic Gene Expression Profile in Wfs1 Knockout Mouse. PPAR Research, 2014, 349525. DOI: 10.1155/2014/349525.
 
Kairane, C.; Mahlapuu, R.; Ehrlich, K.; Zilmer, M.; Soomets, U. (2014). The effects of different antioxidants on the activity of Cerebrocortical MnSOD and Na,K-ATPase from post mortem alzheimer´s disease and age-matched normal brains. Current Alzheimer Research, 11 (1), 79−85.10.2174/15672050113106660179.
 
Oit-Wiscombe, I.; Virag, L.; Soomets, U.; Altraja, A. (2013). Increased DNA damage in progression of COPD: a response by poly(ADP-ribose) polymerase-1. PLoS ONE, 8, e70333.
 
Harzia, Hedi; Ilves, Aire; Ots, Meelis; Henno, Merike; Jõudu, Ivi; Kaart, Tanel; Ling, Katri; Kärt, Olav; Kilk, Kalle; Soomets, Ursel (2013). Alterations in milk metabolome and coagulation ability during the lactation of dairy cows. Journal of Dairy Science, 96 (10), 6440−6448. DOI: 10.3168/jds.2013-6808.
 
Kazarjan, J.; Vaher, M.; Mahlapuu, R.; Hansen, M.; Soomets, U.; Kaljurand, M. (2013). Separation of glutathione and its novel analogues and determination of their dissociation constants by capillary electrophoresis. Electrophoresis, 34 (12), 1820−1827. DOI: 10.1002/elps.201200611.
 
Kõks, S.; Overall, R.W.; Ivask, M.; Soomets, U.; Guha, M.; Vasar, E.; Fernandes, C.; Schalkwyk, L.C. (2013). Silencing of the WFS1 gene in HEK cells induces pathways related to neurodegeneration and mitochondrial damage. Physiological Genomics, 45 (5), 182−190. DOI: 10.1152/physiolgenomics.00122.2012.
 
Harzia, Hedi; Kilk, Kalle; Ariko, Tiia; Kass, Marko; Soomets, Ursel; Jõudu, Ivi; Kaart, Tanel; Arney, David; Kärt, Olav; Ots, Meelis (2013). Crude glycerol as a glycogenic precursor in feed: effects on milk coagulation properties and metabolic profiles of dairy cows. Journal of Dairy Research, 80 (2), 190−196. DOI: 10.1017/S0022029913000101.
 
Laanemets, Kristiina; Wang, Yong-Fei; Lindgren, Ove; Wu, Juyou; Nishimura, Noriyuki; Lee, Stephen; Caddell, Daniel; Merilo, Ebe; Brosche, Mikael; Kilk, Kalle; Soomets, Ursel ; Kangasjarvi, Jaakko; Schroeder, Julian I.; Kollist, Hannes (2013). Mutations in the SLAC1 anion channel slow stomatal opening and severely reduce K+ uptake channel activity via enhanced cytosolic [Ca2+] and increased Ca2+ sensitivity of K+ uptake channels. New Phytologist, 197 (1), 88−98. DOI: 10.1111/nph.12008.
 
Altraja, S.; Mahlapuu, R.; Soomets, U.; Altraja, A. (2013). Cigarette smoke-induced differential regulation of glutathione metabolism in bronchial epithelial cells is balanced by an antioxidant tetrapeptide UPF1. Experimental and Toxicologic Pathology, 65 (6), 711−717. DOI: 10.1016/j.etp.2012.09.005.
 
Joost, K.; Rodenburg, R.J.; Piirsoo, A.; van den Heuvel, L.; Žordania, R.; Põder, H.; Talvik, I.; Kilk, K.; Soomets, U.; Õunap, K. (2012). A Diagnostic Algorithm for Mitochondrial Disorders in Estonian Children. Molecular Syndromology, 3 (3), 113−119. DOI: 10.1159/000341375.
 
Ilves, Aire; Harzia, Hedi; Ling, Katri; Ots, Meelis; Soomets, Ursel; Kilk, Kalle (2012). Alterations in milk and blood metabolomes during the first months of lactation in dairy cows. Journal of Dairy Science, 95 (10), 5788−5797. DOI: 10.3168/jds.2012-5617.
 
Joost, K.; Õunap, K.; Žordania, R.; Uudelepp, M.-L.; Olsen, R.K.; Kall, K.; Kilk, K.; Soomets, U.; Kahre, T. (2012). Prevalence of long-chain 3-hydroxyacyl-CoA dehydrogenase deficiency in Estonia. JIMD Reports, 2, 79−85.
 
Harzia, H.; Kilk, K.; Jõudu, I.; Henno, M.; Kärt, O.; Soomets, U. (2012). Comparison of the metabolic profiles of noncoagulating and coagulating bovine milk. Journal of Dairy Science, 95 (2), 533−544. DOI: 10.3168/jds.2011-4468.
 
Kõks, S.; Soomets, U.; Plaas, M.; Terasmaa, A.; Noormets, K.; Tillmann, V.; Vasar, E.; Fernandes, C.; Schalkwyk, LC. (2011). Hypothalamic gene expression profile indicates a reduction in G protein signaling in the Wfs1 mutant mice. Physiological Genomics, 43, 1351−1358. DOI: 10.1152/physiolgenomics.00117.2011.
 
Terasmaa, A.; Soomets, U.; Oflijan, J.; Punapart, M.; Hansen, M.; Matto, V.; Ehrlich, K.; Must, A.; Kõks, S.; Vasar, E. (2011). Wfs1 mutation makes mice sensitive to insulin-like effect of acute valproic acid and resistant to streptozocin. Journal of Physiology and Biochemistry, 67 (3), 381−390. DOI: 10.1007/s13105-011-0088-0.
 
Sikk, K.; Kõks, S.; Soomets, U.; Schalkwyk, L.C.; Fernandes, C.; Haldre, S.; Aquilonius, S.M.; Taba, P. (2011). Peripheral blood RNA expression profiling in illicit methcathinone users reveals effect on immune system. Frontiers in Genetics, 2, 42.
 
Kõks, S.; Velthut, A.; Sarapik, A.; Altmäe, S.; Reinmaa, E.; Schalkwyk, L.C.; Fernandes, C.; Lad, H.V.; Soomets, U.; Jaakma, Ü.; Salumets, A. (2010). The differential transcriptome and ontology profiles of mural and cumulus granulosa cells in stimulated human antral follicles. Molecular Human Reproduction, 16 (4), 229−240. DOI: 10.1093/molehr/gap103.
 
Hõrak, P.; Sild, E.; Soomets, U.; Sepp, T.; Kilk, K. (2010). Oxidative stress and information content of black and yellow plumage coloration: an experiment with greenfinches. Journal of Experimental Biology, 213, 2225−2233. DOI: 10.1242/jeb.042085.
 
Viirlaid, S.; Mahlapuu, R.; Kilk, K.; Kuznetsov, A.; Soomets, U.; Järv, J. (2009). Mechanism and stoichiometry of 2,2-diphenyl-1-picrylhydrazyl radical scavenging by glutathione and its novel a-glutamylderivative. Bioorganic Chemistry, 37, 126−132. DOI: 10.1016/j.bioorg.2009.05.001.
 
Meszka-Jordan, A.; Mahlapuu, R.; Soomets, U.; Carlson, G. P. (2009). Oxidative Stress Due to (R)-Styrene Oxide Exposure and the Role of Antioxidants in Non-Swiss Albino (NSA) Mice. Journal of Toxicology and Environmental Health Part A, 72 (10), 642−650. DOI: 10.1080/15287390902769436.
 
Ehrlich, K.; Ida, K.; Mahlapuu, R.; Kairane, C.; Oit, I.; Zilmer, M.; Soomets, U. (2009). Characterization of UPF peptides, members of the glutathione analogues library, on the basis of their effects on oxidative stress-related enzymes. Free Radical Research, 43 (6), 572−580. DOI: 10.1080/10715760902918691.
 
Kilk, K.; Mahlapuu, R.; Soomets, U.; Langel, Ü. (2009). Analysis of in vitro toxicity of five cell-penetrating peptides by metabolic profiling. Toxicology, 265 (3), 87−95.
 
Koks, S.; Soomets, U.; Paya-Cano, J.; Fernandes, C.; Luuk, H.; Plaas, M.; Terasmaa, A.; Tillmann, V.; Noormets, K.; Vasar, E.; Schalkwyk, LC. (2009). Wfs1 gene deletion causes growth retardation in mice and interferes with the growth hormone pathway. Physiological Genomics, 37, 3, 249−259.
 
Kals, J.; Starkopf, J.; Zilmer, M.; Pruler, T.; Pulges, K.; Hallaste, M.; Kals, M.; Pulges, A.; Soomets, U. (2008). Antioxidant UPF1 attenuates myocardial stunning in isolated rat hearts. International Journal of Cardiology, 125 (1), 133−135. DOI: 10.1016/j.ijcard.2007.01.032.
 
Kingo, K.; Aunin, E.; Karelson, M.; Philips, MA; Rätsep, R.; Silm, H.; Vasar, E.; Soomets, U.: Kõks S. (2007). Gene expression analysis of melanocortin system in vitiligo. Journal of Dermatological Science, 48 (2), 113−122.
 
Ehrlich, K.; Viirlaid, S.; Mahlapuu, R.; Saar, K.; Kullisaar, T.; Zilmer, M.; Langel, Ü.; Soomets, U. (2007). Design, synthesis and properties of novel powerful antioxidants, glutathione analogues. Free Radical Research, 41 (7), 779−787.
 
Vaher, Merike; Viirlaid, Säde; Ehrlich, Kersti; Mahlapuu, Riina; Jarvet, Jüri; Soomets, Ursel; Kaljurand, Mihkel. (2006). Characterization of the antioxidative activity of novel nontoxic neuropeptides by using capillary electrophoresis. Electrophoresis, 13, 2582−2589.
 
Mahlapuu, R.; Vaher, M.; Ehrlich, K.; Kaljurand, M.; Soomets, U. (2006). Comparison of stability of glutathione and related synthetic tetrapeptides by HPLC and capillary electrophoresis. Journal of Peptide Science, 12 (12), 796−799.
 
Hallbrink, M.; Kilk, K.; Elmquist, A.; Lundberg, P.; Lindgren, M.; Jiang, Y.; Pooga, M.; Soomets, U.; Langel, U. (2005). Prediction of cell-penetrating peptides. International Journal of Peptide Research and Therapeutics, 11 (4), 249−259.
 
Poder, P.; Zilmer, M.; Starkopf, J.; Kals, J.; Talonpoika, A.; Pulges, A.; Langel, U.; Kullisaar, T.; Viirlaid, S.; Mahlapuu, R.; Zarkovski, A.; Arend, A.; Soomets, U. (2004). An antioxidant tetrapeptide UPF1 in rats has a neuroprotective effect in transient global brain ischemia. Neuroscience Letters, 370 (1), 45−50.
 
Fisher, L.; Soomets, U.; Toro, V.C.; Chilton, L.; Jiang, Y.; Langel, U.; Iverfeldt, K. (2004). Cellular delivery of a double-stranded oligonucleotide NF kappa B decoy by hybridization to complementary PNA linked to a cell-penetrating peptide. Gene Therapy, 11 (16), 1264−1272.
 
Kilk, K.; Elmquist, A.; Saar, K.; Pooga, M.; Land, T.; Bartfai, T.; Soomets, U.; Langel, U. (2004). Targeting of antisense PNA oligomers to human galanin receptor type 1 mRNA. Neuropeptides, 38 (5), 316−324.
 
Mahlapuu, R.; Viht, K.; Balaspiri, L.; Bogdanovic, N.; Saar, K.; Soomets, U.; Land, T.; Zilmer, M.; Karelson, E.; Langel, U. (2003). Amyloid precursor protein carboxy-terminal fragments modulate G-proteins and adenylate cyclase activity in Alzheimer's disease brain. Molecular Brain Research, 117 (1), 73−82.
 
Adlerz, L.; Soomets, U.; Holmlund, L.; Viirlaid, S.; Langel, U.; Iverfeldt, K. (2003). Down-regulation of amyloid precursor protein by peptide nucleic acid oligomer in cultured rat primary neurons and astrocytes. Neuroscience Letters, 336 (1), 55−59.
 
Farquhar, M.; Soomets, U.; Bates, R.L.; Martin, A.; Langel, Ü.; Howl, J. (2002). Novel mastoparan analogs induce differential secretion from mast cells. Chemistry & Biology, 9 (1), 63−70.
 
Saar, K.; Mazarati, AM.; Mahlapuu, R.; Hallnemo, G.; Soomets, U.; Kilk, K.; Hellberg, S.; Pooga, M.; Tolf, BR.; Shi, TS.; Hokfelt, T.; Wasterlain, C.; Bartfai, T.; Langel, U. (2002). Anticonvulsant activity of a nonpeptide galanin receptor agonist. Proceedings of the National Academy of Sciences, 99 (10), 7136−7141.
 
Karelson, E.; Mahlapuu, R.; Zilmer, M.; Soomets, U.; Bogdanovic, N.; Langel, U. (2002). Possible signaling by glutathione and its novel analogue through potent stimulation of frontocortical G proteins in normal aging and in Alzheimer's disease. Annals of the New York Academy of Sciences, 973, 537−540.
 
Rezaei, K.; Xu, IS.; Wu, WP.; Shi, TJ.; Soomets, U.; Land, T.; Xu, XJ.; Wiesenfeld-Hallin, Z.; Hokfelt, T.; Bartfai, T.; Langel, U. (2001). Intrathecal administration of PNA targeting galanin receptor reduces galanin-mediated inhibitory effect in the rat spinal cord. Neuroreport, 12 (2), 317−320.
 
Rezaei, K.; Saar, K.; Soomets, U.; Valkna, A.; Nasman, J.; Zorko, M.; Akerman, K.; Schroeder, T.; Bartfai, T.; Langel, U. (2000). Role of third intracellular loop of galanin receptor type 1 in signal transduction. Neuropeptides, 34 (1), 25−31.
 
Lindgren, M.; Gallet, X.; Soomets, U.; Hallbrink, M.; Brakenhielm, E.; Pooga, M.; Brasseur, R.; Langel, U. (2000). Translocation properties of novel cell penetrating transportan and penetratin analogues. Bioconjugate Chemistry, 11 (5), 619−626.
 
Soomets, U.; Lindgren, M.; Gallet, X.; Hallbrink, M.; Elmquist, A.; Balaspiri, L.; Zorko, M.; Pooga, M.; Brasseur, R.; Langel, U. (2000). Deletion analogues of transportan. Biochimica et Biophysica Acta (BBA) - Biomembranes, 1467 (1), 165−176.
 
Hallbrink, M.; Saar, K.; Ostenson, CG.; Soomets, U.; Efendic, S.; Howl, J.; Wheatley, M.; Zorko, M.; Langel, U. (1999). Effects of vasopressin-mastoparan chimeric peptides on insulin release and G-protein activity. Regulatory Peptides, 82, 45−51.
 
Xu, ZQD.; Ma, XS.; Soomets, U.; Langel, U.; Hokfelt, T. (1999). Electrophysiological evidence for a hyperpolarizing, galanin (1-15)-selective receptor on hippocampal CA3 pyramidal neurons. Proceedings of the National Academy of Sciences of the United States of America, 96 (25), 14583−14587.
 
Soomets, U.; Mahlapuu, R.; Tehranian, R.; Jarvet, J.; Karelson, E.; Zilmer, M.; Iverfeldt, K.; Zorko, M.; Graslund, A.; Langel, U. (1999). Regulation of GTPase and adenylate cyclase activity by amyloid beta-peptide and its fragments in rat brain tissue. Brain Research, 850, 179−188.
 
Bavec, A.; Soomets, U.; Langel, U.; Zorko, M. (1998). Structural features of amphipathic peptides required for the activation of G-proteins. Acta Chimica Slovenica, 45 (1), 27−34.
 
Mazarati, AM.; Liu, HT.; Soomets, U.; Sankar, R.; Shin, D.; Katsumori, H.; Langel, U.; Wasterlain, CG. (1998). Galanin modulation of seizures and seizure modulation of hippocampal galanin in animal models of status epilepticus. Journal of Neuroscience, 18 (23), 10070−10077.
 
Poyner, DR.; Soomets, U.; Howitt, SG.; Langel, U. (1998). Structural determinants for binding to CGRP receptors expressed by human SK-N-MC and Col 29 cells: studies with chimeric and other peptides. British Journal of Pharmacology, 124 (8), 1659−1666.
 
Pooga, M.; Soomets, U.; Hallbrink, M.; Valkna, A.; Saar, K.; Rezaei, K.; Kahl, U.; Hao, JX.; Xu, XJ.; Wiesenfeld-Hallin, Z.; Hokfelt, T.; Bartfai, A.; Langel, U. (1998). Cell penetrating PNA constructs regulate galanin receptor levels and modify pain transmission in vivo. Nature Biotechnology, 16 (9), 857−861.
 
Soomets, U.; Kairane, C.; Zilmer, M.; Langel, U. (1997). Attempt to solubilize Na+/K+-exchanging ATPase with amphiphilic peptide PD1. Acta Chemica Scandinavica, 51 (3), 403−406.
 
Saar, K.; Valkna, A.; Soomets, U.; Rezaei, K.; Zorko, M.; Zilmer, M.; Langel, U. (1997). Role of the third cytoplasmic loop in signal transduction by galanin receptors. Biochemical Society Transactions, 25 (3), 1036−1040.
 
Maeorg, U.; Soomets, U.; Perkson, A.; Linask, K.; Raidaru, G. (1994). Synthesis of 4,4'-dibromobenzilic acid. Mendeleev Communications, 3, 99−100.
 
Soomets, UV.; Palumaa, PJ.; Yarv, JL. (1987). Mechanism of reaction of n,n-dimethyl-2-phenyl-aziridinium ion in acetylcholinesterase active-center. Bioorganicheskaya Khimiya, 13 (2), 198−203.
 
Palumaa, P.; Soomets, U.; Jarv, J. (1985). Effects of reaction medium and temperature on solvolysis of n,n-dimethyl-2-phenylaziridinium ion. Organic Reactivity, 22 (2), 238−257.
1.2. Teadusartiklid teistes rahvusvahelistes teadusajakirjades, millel on registreeritud kood, rahvusvaheline toimetus, rahvusvahelise kolleegiumiga eelretsenseerimine, rahvusvaheline levik ning kättesaadavus ja avatus kaastöödele
 
Lill, M.; Kõks, S.; Soomets, U.; Schalkwyk, LC.; Fernandes, C.; Lutsar, I.; Taba, P. (2013). Peripheral blood RNA gene expression profiling in patients with bacterial meningitis. Frontiers in Neuroscience, 7, 33.10.3389/fnins.2013.00033.
 
Kairane, C.; Mahlapuu, R.; Ehrlich, K.; Kilk, K.; Zilmer, M.; Soomets, U. (2012). Diverse effects of glutathione and UPF peptides on antioxidant defense system in human erythroleukemia cells K562. International Journal of Peptides, 2012, Article ID 124163. DOI: 10.1155/2012/124163.
 
Zilmer, M.; Soomets, U.; Rehema, A.; Langel, Ü. (2005). The glutathione system as an attractive therapeutic target. Drug Design Reviews - Online, 2 (2), 121−127.
 
Soomets, U.; Zilmer, M.; Langel, Ü. (2005). Manual solid-phase synthesis of glutathione analogs: a laboratory-based short course. Methods in Molecular Biology, 298, 241−257.
 
Soomets, U.; Hälbrink, M; Langel, Ü. (1999). Antisence properties of peptide nucleic acids. Frontiers in Bioscience (FBS), 4, D782−D786.
 
Longland, C.; Mezna, M.; Langel, Ü.; Hällbrink, M.; Soomets, U.; Wheatley, M.; Michelangeli, F.; Howl, J. (1998). Biochemical mechanisms of calcium mobilisation induced by mastoparan and chimeric hormone-mastoparan constructs. Cell Calcium, 24 (1), 27−34.
 
Soomets, U.; Hällbrink, M.; Zorko, M.; Langel, Ü. (1997). From galanin and mastoparan to galparan and transportan. Current Topics in Peptide and Protein Research, 2, 83−113.
 
Soomets, U.; Perkson, A. (1990). Synthesis of derivatives of benzilic acid - ligands of muscarinic receptor (in Russian). Experimental Biology, 2, 156−157.
1.3. Eelretsenseeritud teadusartiklid Eesti ja teiste riikide eelretsenseeritavates teadusajakirjades, millel on kohalik toimetuskolleegium, või eelretsenseeritud teadusartiklid Eesti kultuurile olulistes ajakirjades või teadusartiklid ajakirjades Akadeemia, Looming ja Vikerkaar.
 
Aug, Argo; Luik, Katrina; Kilk, Kalle; Soomets, Ursel; Kivastik, Jana; Kingisepp, Peet-Henn; Altraja, Alan (2011). Muutused väljahingatud õhu kondensaadis astma ja kroonilise obstruktiivse kopsuhaiguse korral. Eesti Arst, 459−465.
 
Joost, K.; Kilk, K.; Toome, L.; Soomets, U.; Õunap, K.; Žordania, R. (2008). Pika ahelaga rasvhapete oksüdatsiooni defekt imikul : haigusjuhu kirjeldus. Eesti Arst, 4, 274−279.
 
Soomets, U.; Mahlapuu, R.; Zilmer, M. (2002). Molekulaartehnoloogia praktilise meditsiini teenistuses: antisense tehnika. Eesti Arst, 81 (4), 245−250.
2.2. Monograafiad (sisestatud enne 1. juulit 2014. a.)
 
Soomets, U; Starkopf, J; Zilmer, Mihkel; Karelson, Ello-Rahel; Vihalemm, Tiiu; Zilmer, K; Valkna, A; Sillard, R; Langel, Ü (1996). Bioorganic chemistry for medical students. Tartu: Tartu University.
2.3. Dissertatsioonide seerias ilmunud dissertatsioonid (v.a. käsikirjalised);
 
Soomets, U. (2000). Development of novel transport peptides and their application in antisense techniques. (Doktoritöö, Stockholms universitet). Stockholm: Department of Neurochemistry and Neurotoxicology, Arrhenius Laboratories for Natural Sciences.
2.4. Kõrgkooliõpikud
 
Zilmer, M.;Soomets, U.; Rehema, A.; Altraja, S.; Mahlapuu, R.; Porosk, R.; Zilmer, K.; Kullisaar, T.; Kilk, K.; Kairane, C.; Salum, T. (2018). Inimkeha põhilised biomolekulid (meditsiiniliselt tähtsamad ülesanded). Avita.
3.1. Artiklid/peatükid lisas loetletud kirjastuste välja antud kogumikes (kaasa arvatud Web of Science Book Citation Index, Web of Science Conference Proceedings Citation Index, Scopus refereeritud kogumikud)
 
Ceslava Kairane, Riina Mahlapuu, Ülle Helena Meren, Kersti Zilmer, Ursel Soomets, Mihkel Zilmer (2014). Do Inhaled Glucocorticosteroids (In Vivo), Oral N-Acetylcysteine (In Vivo) and Glutathione (In Vitro) Affect Blood Redox Status in Chronic Obstructive Pulmonary Disease Patients? International Symposium on Medicinal Chemistry, Lisbon, Portugal September 7-11, 2014. Ed. Wiley Online Library. Wiley-V C H Verlag Gmbh, 163.
 
Jiang, Y.; Soomets, U.; Langel, Ü. (2006). Design and synthesis of CPPs. In: Langel, Ü (Ed.). Handbook of Cell-Penetrating Peptides, 2nd Edition (537−551).. CRC Press Inc.
 
Valkna, A.; Soomets, U.; Langel, Ü. (2002). Cell-penetrating peptides as vectors for delivery of nucleic acids. In: Langel, Ü. (Ed.). Cell Penetrating Peptides. Processes and Applications (347−363). . New York: CRC Press Inc.
 
Pooga, M.; Soomets, U.; Bartfai, T.; Langel, Ü. (2002). Synthesis of cell-Penetrating peptide-PNA constructs. In: Nielsen, P. (Ed.). Peptide nucleic acids: methods and protocols (225−236). . Totowa, NJ: Human Press. (Methods in molecular biology; 208).
 
Soomets, U.; Langel, Ü. (1999). Intracellular third loop of galanin receptor as G-protein interaction site. Peptides. Frontiers of Peptide Science: 15th American Peptide Symposium; Nashville, Tennessee; 14.-19.06.1997. Ed. Tam, J.P.; Kauyama, P.T.P. Dodrecht: Kluwer Academic Publishers, 662−663.
3.2. Artiklid/peatükid lisas mitte loetletud kirjastuste välja antud kogumikes
 
Kilk, K.; Terasmaa, A.; Soomets, U. (2008). Biochemistry of wolframin. In: Kõks, S.; Vasar, E. (Ed.). WFS1 Protein (Wolframin): Emerging Link Between the Emotional Brain and Endocrine Pancreas (87−106). . Fort P.O., Trivandrum-695 023, Kerala, India: Research Signpost.
 
Poyner, D.R.; Howitt, S.; Soomets, U.; Langel, Ü. (2000). Structure activity relationship for CGRP receptor ligands. In: Poyner, D.; Marshall, I.; Brain, S.D. (Ed.). The CGRP family: Calcitonin Gene-Related Peptide (Cgrp), Amylin, & Adrenomedullin (25−32).. Georgetown: Landes Bioscience.
 
Soomets, U.; Kilk, K.; Land, T.; Langel, Ü. (2000). Transportan, its analogues and their applications. Innovation and Perspectives in Solid Phase Synthesis and Combinatorial Libraries: Peptides, Proteins and Nucleic Acids. Proceedings of the 5th International Symposium, London. Ed. Epton, R. Kingswinford, England: Mayflower Worldwide, 131−136.
3.4. Artiklid/ettekanded, mis on avaldatud valdkonda 3.1. mittekuuluvates konverentsikogumikes
 
Ilves, Aire; Harzia, Hedi; Ling, Katri; Kaart, Tanel; Soomets, Ursel; Kilk, Kalle; Ots, Meelis (2013). Metabolomics as a novel tool for energy balance indication of dairy cows. 15th International Conference on Production Diseases in Farm Animals. Book of Abstracts.: ICPD 2013, Uppsala, Sweden, 24-28 June 2013. Ed. Göran Dalin. Swedish University of Agricultural Sciences, 137−137.
 
Ilves, Aire; Ling, Katri; Kilk, Kalle; Soomets, Ursel (2012). Changes in milk metabolome of dairy cows during the first months of lactation. Dairy production in modern loose housing cowsheds - practical implications and future challenges: NJF seminar 439. Dairy production in modern loose housing cowsheds - practical implications and future challenges. 2-4 May 2012, Tartu, Estonia. Ed. Kaasik, Allan. Tartu, Estonia, 29.
 
Ilves, Aire; Harzia, Hedi; Ling, Katri; Kärt, Olav; Soomets, Ursel; Kilk, Kalle (2011). Negative energy balance induced changes in milk metabolome of dairy cows. International Oskar Kellner Symposium. Metabolic Flexibility in Animal and Human Nutrition.: International Oskar Kellner Symposium. Metabolic Flexibility in Animal and Human Nutrition. Warnemünde, Germany, September 9-11, 2011. Ed. Cornelia C. Metges; Harald M. Hammon; Björn Kuhla; Monika Röntgen; Wolfgang B. Souffrant. Germany: Alstadt-Druck GmbH, 55−55.
 
Farquhar, M.; Soomets, U.; Brown, C.; Martin, A.; Bates, R.; Langel, Ü.; Howl, J. (2001). Venomous chimeric secretagogues. Peptides 2000: European Peptide Symposium; Montpellier, France; 10.-15.09.2000. Ed. Martinez, J.; Fehrentz, J.A. Paris: EDK, 633−634.
 
Brown, J.; Howl, J.; Martin, A.; Soomets, U.; Langel, Ü.; Brown, C. (2001). Single amino-acid substitutions in a mimetic tetradecapeptide agonist of the human P2Y2 receptor prevent second messenger activation. Peptides 2000: European Peptide Symposium; Montpellier, France; 10.-15.09.2000. Ed. Martinez, J.; Fehrentz, J.A. Paris: EDK, 913−914.
3.5. Artiklid/ettekanded, mis on avaldatud kohalikes konverentsikogumikes
 
Soomets, U; Ehrlich, K; Kullisaar, T; Mahlapuu, R; Pechter, Ü; Rosenberg, M; Sepp, K. (2008). Effect of novel antioxidant compound UPF on chronic kidney injury. Scand-Las and ICLAS Joint Meeting 2008 Abstract book: Scand-Las and ICLAS Joint Meeting 2008, 8-11 May, Tartu, Estonia. Tartu: Tartu University Press, 30.
5.1. Konverentsiteesid, mida kajastab Thomson Reuters Web of Science
 
Kairane, C; Mahlapuu, R; Porosk, R; Zilmer, M; Soomets, U. (2018). The effects of glutathione analogues on Na,K-ATPase activity in the kidneys of the wildtype and the Wfs1 gene mutated mice in vitro and in vivo. Journal of Peptide Science: 35th European Peptide Symposium, Dublin City University, Ireland, 26th - 31st August 2018. Wiley Online Library, 136.
 
Zagura, Maksim; Kals, Jaak; Paapstel, Kaido; Kilk, Kalle; Serg, Martin; Kampus, Priit; Eha, Jaan; Soomets, Ursel; Zilmer, Mihkel. (2015). Metabolomic characteristics of arterial stiffness in patients with peripheral arterial disease. Cardiology, 241: Nordic-Baltic Cardiology Congress, Tallinn, 4.06-6.06.2015. Karger, E150−E151.
 
Altraja, A.; Aug, A.; Kilk, K.; Mahlapuu, R.; Altraja, S.; Soomets, U. (2014). Phenotyping of chronic obstructive pulmonary disease by integrated metabolomic profiling of exhaled breath condensate. American Journal of Respiratory and Critical Care Medicine, 189, A5880.
 
Aug, A.; Altraja, S.; Kilk, K.; Mahlapuu, R.; Soomets, U.; Altraja, A. (2014). E-cigarettes profoundly affect metabolome of primary human bronchial epithelial cells. European Respiratory Journal, 44 (Suppl. 58), 1834.
 
Aug, A.; Altraja, S.; Kilk, K.; Laaniste, L.; Mahlapuu, R.; Soomets, U.; Altraja, A. (2013). Acute effect of cigarette smoke on human bronchial epithelial cell metabolome is reversible by UPF1. European Respiratory Journal, 42, 819s.
 
Kairane, C.; Mahlapuu, R.; Zilmer, M.; Soomets, U. (2012). The effects of bioactive thiols on the activity of CuZnSOD of the patiens with chronic obstructive pulmonary disease in vitro and in vivo. 279: 22nd IUBMB and 37th FEBS Congress, Seville, Spain September 4-9, 2012. The FEBS Journal, 210. (Suppl. 1).
 
Soomets, U.; Kingo, K.; Mahlapuu, R.; Koks, S. (2011). Antioxidants have possible therapeutic activity for psoriasis. 6th International Congress of Psoriasis - from Gene to Clinic. , E28−E28.
 
Altraja, S.; Soomets, U.; Mahlapuu, R.; Altraja, A. (2011). Differential regulation of glutamate-cysteine ligase subunits by 4-hydroxy-2-nonenal is balanced by an antioxidant tetrapeptide UPF1. American Journal of Respiratory and Critical Care Medicine, 183, A5965.
 
Asser, A.; Kõks, S.; Soomets, U.; Terasmaa, A.; Sauk, M.; Eltermaa, M.; Piip, P.; Taba, P. (2010). Acute effects of methcathinone and manganese in mice: a dose response study. Movement Disorders, 25, S226−S226.
 
Sikk, K.; Koks, S.; Soomets, U.; Schalkwyk, L.; Fernandes, C.; Haldre, S.; Aquilonius, SM.; Taba, P. (2010). Peripheral blood RNA gene expression profiling in illicit methcathinone users reveals effect on immune system. Movement Disorders, 25, S226−S226.
 
Altraja, S.; Mahlapuu, R.; Soomets, U.; Altraja, A. (2010). An antioxidant tetrapeptide UPF1 maintains glutathione level in normal human bronchial epithelial cells exposed to oxidative stress. American Journal of Respiratory and Critical Care Medicine, 181, A2686.
 
Altraja, S.; Mahlapuu, R.; Soomets, U.; Altraja, A. (2010). The effect of antioxidant tetrapeptide UPF1 on enzymes involved in glutathione metabolism in human bronchial epithelial cells exposed to oxidative stress. European Respiratory Journal, 36(Suppl.54), 438s.
 
Joost, K.; Kilk, K.; Soomets, U.; Õunap, K. (2009). Selective screening of fatty acid oxidation effects in Estonia: one year experience. Molecular Genetics and Metabolism: 11th International Congress of Inborn Errors of Metabolism; San Diego, USA; 29.08 - 2.09.2009. Elsevier, 56. (98).
 
Fisher, L.; Samuelsson, M.; Toro, V. C.; Soomets, U.; Yang, J.; Langel, Ü.; Iverfeldt, K. (2004). Downregulation of Abeta-induced cytokine expression in glial cells using NFkappaB decoy. Journal of Neuroimmunology, 154, 31−31.
 
Zilmer, M.; Soomets, U.; Karelson, E.; Mahlapuu, R.; Zilmer, K.; Langel, U. (2002). Glutathione-like peptide as an antioxidative protector molecule. Free Radical Biology and Medicine, 33, S216−S216.
5.2. Konverentsiteesid, mis ei kuulu valdkonda 5.1
 
Kairane, Ceslava; Mahlapuu, Riina; Porosk, Rando; Zilmer, Mihkel; Soomets, Ursel (2016). THE EFFECT OF GLUTATHIONE ANALOGUES UPF1 AND UPF17 ON NA,K-ATPASE ACTIVITY IN THE KIDNEYS OF C57BL/6 MICE IN VITRO AND IN VIVO. XXIV EFMC International Symposium on Medicinal Chemistry BOOK OF ABSTRACTS: XXIV EFMC International Symposium on Medicinal Chemistry UK Manchester from August 28 - September 1, 2016.. LD Organisation Scientific Conference Producers, Belgium, 140.
 
Altraja, A.; Aug, A.; Kilk, K.; Mahlapuu, R.; Altraja, S.; Soomets, U. (2015). Phenotyping of COPD by integrated metabolomic profiling of exhaled breath condensate and peripheral blood. European Respiratory Journal, 46 (Suppl.59), OA2922.
 
Taalberg, E.; Porosk, R.; Mahlapuu, R.; Soomets, U. (2015). Glutatiooni seleno- ja esteranaloogide disain, süntees ja omaduste uurimine. Eesti Arst, 40.
 
Porosk, R.; Mahlapuu, R.; Kairane, C.; Zilmer, M.; Soomets, U. (2015). DO NOVEL GSH ANALOGUES ALLEVIATE THE COMPLICATIONS OF DIABETES IN VIVO? JMMC - 2015 Abstracts: IX Joint Meeting on Medicinal Chemistry. June 7-10, 2015 Athens, Greece..
 
Zagura, Maksim; Kals, Jaak; Paapstel, Kaido; Kilk, Kalle; Serg, Martin; Kampus, Priit; Eha, Jaan; Soomets, Ursel; Zilmer, Mihkel. (2014). Metabolomic Signature of Arterial Stiffness in Patients with Peripheral Arterial Disease. Final Programme and Abstracts: Rahvusvaheline kongress: Artery 14, 9.-11. oktoober 2014 Maastricht, Holland. , 8.
 
Zagura, Maksim; Kals, Jaak; Paapstel, Kaido; Kilk, Kalle; Serg, Martin; Kampus, Priit; Eha, Jaan; Soomets, Ursel; Zilmer, Mihkel. (2014). Arterite jäikuse metaboloomiline profiil alajäsemete arterite ateroskleroosiga patsientidel. Eesti Arst. , 31.
 
Kairane, C.; Mahlapuu, R.; Hansen, M.; Soomets, U.; Zilmer, M. (2013). The significance of the configuration of peptides on their biological activities. VIIIth Joint Meeting on Medicinal Chemistry, June 30-July 4 2013, Lublin. P-18.
 
Antoniak, KM; Kairane, C; Mahlapuu, R; Zilmer, M; Soomets, U. (2013). Glutatiooni analoogi UPF17 mõju in vivo NaK-ATPaasi aktiivsusele tervete ja Wsf1 geenimutatsiooniga hiirte neerudes. Eesti Arst, 92 (Lisa2): Tartu Ülikooli arstiteatuskonna aastapäeva teaduskonverents 2013. 31.
 
Porosk, R; Kilk, K; Mahlapuu, R; Soomets, U. (2013). Wfs1 geeni defektiga hiire metaboloomi kirjeldus. Eesti Arst, 92 (Lisa2): Tartu Ülikooli arstiteaduskonna aastapäeva teaduskonverents 2013. , 30.
 
Oit, I.; Soomets, U.; Altraja, A. (2013). Glutathione antioxidant system – a defense mechanism in COPD. Proceedings of the 12th International Conference on Oxidative Stress, Redox States and Antioxidants/15th Anniversary of ISANH, Paris, 3-4 July 2013.
 
Aug, A.; Altraja, S.; Kilk, K.; Laaniste, L.; Mahlapuu, R.; Soomets, U.; Altraja, A. (2012). Antioxidant tetrapeptide UPF1 exerts an immediate effect on cigarette smoke-altered metabolic state of human bronchial epithelial cells. European Respiratory Journal, 40, 837s.
 
Altraja, S.; Mahlapuu, R.; Soomets, U.; Altraja, A. (2012). The effect of an antioxidant tetrapeptide UPF1 on glutathione metabolism in human bronchial epithelial cells exposed to cigarette smoke. American Journal of Respiratory and Critical Care Medicine, 185, A1256.
 
Harzia, Hedi; Kilk, Kalle; Jõudu, Ivi; Henno, Merike; Kärt, Olav; Soomets, Ursel (2012). Metabolome of non- and coagulating cows milk. Book of abstracts ESR workshop "Feed your knowledge!", 7-8 June 2012, Barcelona, Spain: Feed your knowledge! workshop, 7-8 June 2012, Barcelona, Spain. Ed. Tres, Alba; Altintzoglou,Themistokilis; Livingstone, Katherine; Frankic, Tamara; Pinotti, Luciano; D., 44.
 
Harzia, Hedi; Kilk, Kalle; Jõudu, Ivi; Henno, Merike; Kärt, Olav; Soomets, Ursel (2012). Metabolic profiles of non- and coagulating bovine milk. Dairy production in modern loose housing cowsheds - practical implications and future challenges: NJF seminar 439. Dairy production in modern loose housing cowsheds - practical implications and future challenges. 2-4 May 2012, Tartu, Estonia. Ed. Kaasik, Allan. Tartu, Estonia, 44−45.
 
Kase, G.; Kairane, C.; Mahlapuu, R.; Soomets, U. (2012). The effect of GSH analogues UPF6 and UPF19 on the glutathione levels and GSSG/GSH ratio in the mouse liver. International Pharmacy Graduation Projects Symposium 15-16 June Haziran 2012. Near East University Faculty of Pharmacy, 38.
 
Siitas, M.; Kairane, C.; Mahlapuu, R.; Soomets, U.; Zilmer, M. (2012). GSH analoogi UPF17 mõju in vivo GSH redoksstaatusele metsikut tüüpi ja Wfs1 geenmutatsiooniga hiirte maksas. 91: Tartu Ülikooli Arstiteaduskonna aastapäeva teaduskonverents 2012. Eesti Arst, 34.
 
Kase, G.; Kairane, C.; mahlapuu, R.; Soomets, U.; Zilmer, M. (2012). Glutatiooni analoogide UPF6 ja UPF19 in vivo mõju glutatiooni tasemele ja redokssuhtele hiire maksas. 91: Tartu Ülikooli Arstiteaduskonna aastapäeva teaduskonverents 2012. Eesti Arst , 33.
 
Oit, I.; Virág, L.; Soomets, U.; Altraja, A. (2012). COPD as a systemic disease. Proceedings of the FEBS 3+ Meeting, 283.
 
Kairane, C.; Mahlapuu, R.;Soomets, U.; Zilmer, M. (2011). The effect of glutathione and its analogue UPF17 on activity of frontal cortical Na,K-ATPase of Alzheimer`s disease in vitro. Amino Acids, 41 (1), 47−48.
 
Joost, K; Kahre, T; Kilk, K; Uudelepp, M-L; Soomets, U; Õunap, K. (2010). Pika ahelaga hüdroksü-atsüül CoA dehüdrogenaasi defitsiidi esinemine Eestis. Eesti Arst, 98: Eesti Arstiteaduskonna Päevad, Tartu, oktoober 2010. , 563. (9).
 
Lill, M.; Kõks, S.; Soomets, U.; Schalkwyk, LC.; Fernandes, C.; Lutsar, I., Taba, P. (2010). Peripheral blood RNA gene expression profiling in the patients with community-acquired bacterial meningitis. In: (x).20th European Congress of Clinical Microbiology and Infectious Diseases, Vienna, Austria, 10 - 13 April.
 
Kivastik, J.; Kingisepp, PH.; Kilk, K.; Soomets, U.; Aug, A.; Luik, K.; Altraja, A. (2010). Changes in exhaled breath condensate in asthma and COPD: a full analysis of mass spectra. European Respiratory Journal, 36(Suppl. 54), 227s.
 
Oit, I.; Hansen, M.; Soomets, U.; Altraja, A. (2010). Põletiku ja oksüdatiivse stressiga seotud ensümaatiliste markerite geeniekspressiooni muutused KOK-haigetel sõltuvalt haiguse raskusastmest. Uute antioksüdantsete peptiidide mõju. Eesti Arst, 89 (9), 584−584.
 
Kairane, C.; Mahlapuu, R.; Ehrlich, K.; Soomets, U.; Zilmer, M. (2010). The significance of structural modifications of UPF peptides , glutathione analogues, on CuZnSOD activity of K562 cells. 18th European Symposium on Quantitative Structure-Activity Relationships; Rhodes, Greece; 19-24 September 2010. 267.
 
Mahlapuu, R.; Vaher, M.; Ida, K.; Soomets, U. (2010). Glutatiooni analoogide mõju raku redokstsükli ensüümide aktiivsusele. XXXI Eesti Keemiapäevad, Tallinn 2010. , 52.
 
Kilk, K., Mahlapuu, R., Viirlaid, S., Järv, J., Soomets, U. (2009). Identification of pharmacophores in antioxidative UPF peptides. European Journal of Pharmaceutical Sciences, 38: 3rd BBBB-Bosphorus International Conference on Pharmaceutical Sciences; Antalya, Turkey; 26-28.10.2009. Elsevier Science BV, 157−158. (1).
 
Oit, I., Mahlapuu, R., Raud, K., Kingo, K., Soomets, U. (2009). Effects of novel glutathione analogues on the expression of antioxidative enzymes. Abstract Book and Program: 5th Conference on Separation and Related Techniques by Nordic Separation Sciemce Society; Tallinn, Estonia; 26-29.08.2009. Ed. Borissova, M., Vaher, M. Infotrükk OÜ, 122.
 
Kairane, C.; Mahlapuu, R.; Tarros, K.; Soomets, U.; Zilmer, M. (2009). Differential regulation of CuZn-superoxide dismutase activity in K562 cells by glutathione and its synthetic analogue alpha-glutathione. 45th International Conference on Medicinal Chemistry; University Orleans, France; July 1-3, 2009. 86.
 
Mahlapuu, R.; Vaher, M;. Ida, K.; Viirlaid, S.; Kaljurand, M.; Soomets, U. (2009). Dimerisation of glutathione analogues in the presence of cellular redox cycle enzymes. Abstract Book and Program: 5th Conference on Separation and Related Techniques by Nordic Science Society. Toim. Maria Borissova, Merike Vaher. Tallinn University of Technology Press, 112.
 
Kilk, K.; Mahlapuu, R.; Viirlaid, S.; Järv, J.;Soomets, U. (2009). Pharmacophores in antioxidative UPF peptides. European Journal of Pharmaceutical Sciences, 38 (1), 157.
 
Tõnisson, N.; Laidre, P.; Ilisson, P.; Ilus, T.; Tammur, P.; Kuuse, K.; Kruustük, K.; Teek, R.; Joost, K.; Soomets, U.; Sitska, M.; Muru, K.; Kerna, I.; Kahre, T.; Reimand, T.; Õunap, K. (2009). Kliinik 2009 [Videosalvestis] : uusi diagnostikavõimalusi kliinilises geneetikas. Kliinik 2009, Tartu Ülikooli Kliinikumi täienduskonverents(2009 :Tartu). Tartu: TÜ IT Multimeedia talitus.
 
Kõks, S.; Velthut, A.; Sarapik, A.; Reinmaa, E.; Soomets, U.; Jaakma, Ü.; Salumets, A. (2008). Folliikuli granuloosa rakkude funktsionaalne diferentseerumine: transkriptoomi uuringud. Eesti Arst, 9. , 688−689.
 
Oit, I.; Mahlapuu, R.; Raud, K.; Kingo, K.; Soomets, U. (2008). Glutatiooni analoogide mõju psoriaasihaigete mõningate antioksüdantsete ensüümide ekspressioonile. Eesti Arst 87(9): TÜ Arstiteaduskonna päevad; Tartu; 9. oktoober 2008. , 670.
 
Mahlapuu, R.; Viirlaid, S.; Ehrlich, K.; Saar, K.; Soomets, U. (2007). Novel tetrapeptidic glutathione analogues: chemical activity in vitro. Abstracts of Scientific Conference: 30th Estonian Chemistry Days. , 86−87.
 
Ehrlich, K.; Viirlaid, S.; Mahlapuu, R.; Saar, K.; Zilmer, M.; Soomets, U. (2007). UPF peptiidid, antioksüdasntsed glutatiooni analoogid - disain, vabade radikaalide eliminatsioon in vitro ja toksilisus K562 rakkudele. Eesti Arst, 86 (9), 705.
 
Mahlapuu, R.; Ehrlich, K.; Kairane, C.; Soomets, U. (2007). Novel UPF analogues affect glutathione peroxidase and glutathione reductase activity. Farmacevtski vestnik: 5th Joint Meeting on Medicinal Chemistry, June 14-21, 2007, Portorož, Slovenia. 135 .
 
Ehrlich, K.; Viirlaid, S.; Mahlapuu, R.; Saar, K.; Zilmer, M.; Soomets, U. (2007). UPF peptides, antioxidative glutathione analogues – design, free radical scavenging in vitro and toxicity to K562 cells. Free Radical Research, 41: European Meeting of the Society for Free Radical Research; 10-13 October; Vilamoura, Portugal. Free Radical Research, 25. (1).
 
Ehrlich, Kersti; Mahlapuu, Riina; Zilmer, Mihkel; Soomets, Ursel (2006). Sünteetilised glutatsiooni analoogid kui võimalikud neutrofiilide NAD(P)H oksüdaasi poolt produtseeritud superoksiidi radikaali elimineerijad. Eesti Arst, 9, 616.
 
Vaher, M.; Mahlapuu, R.; Ebber, A.; Soomets, U.; Kaljurand, M. (2006). Monitoring the oxidation of the gluthatione and related neuropeptides by capillary electrophoresis. Abstractbook of 10th Naples workshop on bioactiv peptides: 10th naples workshop on bioactive peptides Naples 11-14 June 2006. , 142−143.
 
Raud, K.; Kingo, K.; Ehrlich, K.; Kõks, S.; Silm, H.; Vasar, E.; Soomets, U. (2006). Glutatsioonisüsteemi regulatsioon psoriaasi korral. Eesti Arst, 85 (9): Arstiteaduskonna päevad 2006. , 633−634.
 
Ehrlich, K.; Mahlapuu, R.; Viirlaid, S.; Zilmer, M.; Langel, Ü.; Soomets, U. (2005). Antioxidative properties of novel antioxidant UPF1 and its analogues. 1st BBBB Conference on Pharmaceutical Sciences, Siofok, Hungary,September 26-28. , 132−133.
 
Pruler, T.; Pulges, K.; Hallaste, M.; Kals, J.; Soomets, U.; Starkopf, J.; Pulges, A.; Zilmer, M. (2004). Antioksüdant UPF-1 parandab isheemiajärgset kontraktiilset funktsiooni isoleeritud rotisüdametel. Eesti Arst, 83 (9), 634.
 
Põder, P.; Kals, J.; Talonpoika, A.; Soomets, U.; Starkopf, J.; Arend, A.; Pulges, A.; Zilmer, M. (2001). Peptiid UPF 1 kaitseb roti aju isheemilise kahjustuse eest. Eesti Arst, 80 (9), 415.
 
Soomets, U.; Kilk, K.; Mahlapuu, R.; Zilmer, M. (2000). Peptiidsete nukleiinhapete ja uute transport-peptiidide kasutamine antisense tehnikas. Eesti Arst, 79 (9), 568.
6.2. Õpikud ja muud õppeotstarbelised publikatsioonid, v.a. kõrgkooliõpikud;
 
Porosk, R.; Kilk, Kalle.; Mahlapuu, R.; Soomets, U. (2018). Bioorgaanilise keemia põhimõisted.
 
Soomets, U.; Kilk, K.;Ottas, A.; Porosk, R.; Mahlapuu, R.; Zilmer, M. (2018). Inimese ainevahetusega seotud metaboliitide struktuur, reaktsioonivõime ja biofunktsioonid. Biokeemia I osa.
 
Soomets, U.; Zilmer, M.; Starkopf, J.; Karelson, E.-R.; Vihalemm, T.; Zilmer, K.; Sillard, R.; Bourne, J; Langel, Ü. (1999). Selected knowledge for medical biochemistry. Tartu: Tartu Ülikooli Kirjastus.
 
Karelson, E.; Soomets, U.; Zilmer, M.; Vihalemm, T.; Zilmer, K. (1998). Valitud peatükid meditsiinilise biokeemia jaoks. Tartu: Tartu University Press.
 
Soomets, U.; Karlström, A.; Zilmer, M.; Langel, Ü. (1998). Solid phase peptide synthesis of glutathione and its analogs by Fmoc- and tert-Boc-chemistry. Manual for laboratory course. Tartu: Tartu University Press.
 
Soomets, U.; Zilmer, M.; Karelson, E.-R.; Vihalemm, T.; Valkna, A.; Zilmer, K. (1995). Bioorgaaniline keemia arstiteaduskonna üliõpilastele. Tartu: Tartu Ülikool.
6.3. Populaarteaduslikud artiklid;
 
Pooga, M.; Langel, Ü.; Hansen, M., Soomets, U.; Kilk, K. (2009). Rakusisesed märklauad. Villems, R. (Toim.). Eesti Vabariigi Teaduspreemiad (72−85). . Tallinn: Eesti Teaduste Akadeemia.
6.6. Muudes ajakirjades ja ajalehtedes avaldatud artiklid;
 
Mahlapuu, R., Soomets, U., Zilmer, M., Langel, Ü. (2004). Alzheimeri tõve molekulaarsed alused: osalevad valgud ja peptiidid: uued ravistrateegiad. Lege Artis, 8 (32), 10−14.
6.7. Muu loome
 
Soomets, U. (1994). 4,4' -dibromobensiilhappe ja selle derivaatide süntees. (Magistritöö, Tartu Ülikool). Tartu: Tartu Ülikool.

Industrial property

18.01.2022