Vallo Matto

https://www.etis.ee/CV/Vallo_Matto/est
4.02.1969
737 5197
vallo.matto@ut.ee

Teenistuskäik

Töökohad ja ametid
(1)1989-1991 ja 1992-1993 TÜ Psühhiaatriakliiniku lasteosakonna hooldaja ja med.-vend
(2) 1993-1997 TÜ Farmakoloogia Instituudi vanemlaborant ja assistent (osalise koormusega)
(3) 1997-1998 TÜ Farmakoloogia Instituudi assistent
(4) 1999 TÜ Farmakoloogia Instituudi vanemassistent
(5) 1999–2001 TÜ Farmakoloogia Instituudi erakorraline vanemteadur
(6) 2002–2004 TÜ Farmakoloogia Instituudi vanemassistent
(7) 2003 Helsingi Ülikooli (HÜ) neurofüsioloogia teadur
(8) 2004-2005 HÜ neurofüsioloogia vanemteadur
01.09.2014–31.08.2015   
Tartu Ülikool, Arstiteaduskond, Farmaatsia instituut, farmaatsia vanemteadur (0,25)
01.09.2010–31.08.2014   
Tartu Ülikool, Arstiteaduskond, Farmaatsia instituut, farmaatsia vanemteadur (1,00)
2005–2005   
Tartu Ülikool, Arstiteaduskond, Farmaatsia instituut, erakorraline vanemteadur (1,00)
2005–31.08.2010   
Tartu Ülikool, Arstiteaduskond, Farmaatsia instituut, Ravimite tehnoloogia ja biofarmaatsia õppetool, Vanemteadur (1,00)
 
 
Haridustee
(1) 1976-1987 Tallinna 42. Keskkool, õpilane
(2) September 1987 - Juuni 1991 Tartu Ülikooli Arstiteaduskonna üliõpilane
(3) August 1991- Jaanuar 1992 Helsingi Ülikooli Arstiteaduskonna üliõpilane
(4) Jaanuar 1992 - Juuni 1993 Tartu Ülikooli Arstiteaduskonna üliõpilane
(5) Juuni 1993 - Tartu Ülikooli Arstiteaduskonna lõpetaja, arsti aste
(6) September 1993 - Jaanuar 1998 Tartu Ülikooli Farmakoloogia Instituudi doktorant
(7) 3. juuni 1998, Tartu Ülikool, meditsiinidoktor
 
 
Teadusorganisatsiooniline ja -administratiivne tegevus
2007−2007   
(3) 2nd BBBB Conference on Pharmaceutical Sciences (September, 2007), konverentsi teadussekretär
2001−2001   
(2) 2nd Baltic Regional Meeting of Biological Psychiatry (Mai-Juuni, 2001) organiseerimiskomitee sekretär
1995−1995   
(1) Rudolf Buchheim Conference in Neuropharmacology (Mai, 1995) organiseerimiskomitee liige

Kvalifikatsioon

Teaduskraadid
Vallo Matto, doktorikraad, 1998, (juh) Lembit Allikmets, Pharmacological studies on anxiogenic and antiaggressive properties of antidepressants, Tartu Ülikool, Arstiteaduskond.
 
 
Teaduspreemiad ja tunnustused
2004, Vallo Matto, ESRS Poster Prize, Praha Tshehhi Vabariik, 5–9 oktoober 2004, European Sleep Research Society 17th Congress
2001, Vallo Matto, WFSBP Young Investigator Travel Award 2001
2000, Vallo Matto, European College of Neuropsychopharmacology (ECNP) Fellowship Award, 2000
2000, Vallo Matto, 1st Baltic Regional Meeting in Biological Psychiatry, WFSBP postrerite 1. preemia, Vilnius, Leedu, 2000
1998, Vallo Matto, Lundbeck Eesti AS 1998 auhind bioloogilises psühhiaatrias (koos mag. Tatjana Skrebuhhova-Malmros’iga)
1997, Vallo Matto, “Ants and Maria Silvere and Sigfried Pant Memorial Scholarship at Tartu University Foundation” stipendium, 1997
1997, Vallo Matto, The European Neuropeptide Club Award, 1997
1997, Vallo Matto, Eesti Vabariigi Haridusministeeriumi üliõpilaste teadustööde konkursi 3. koht, 1997
 
 
Teadustöö põhisuunad
VALDKOND: 3. Terviseuuringud; 3.3. Farmaatsia; PÕHISUUND: Praegune töösuund: Ravipreparaatide keemilised, füsiokeemilised ja biofarmatseutilised uuringud - kvaliteedi hindamine ja parandamine, projektijuht prof. P. Veski . Projekti raames uuriti raviainet modifitseeritult vabastavate tahkete peroraalsete ravimvormide in vitro analüüsimeetodi täiustamist: võrreldi kolme meetodit (poolvahetusmeetod, täisvahetusmeetod, TRIS-meetod), meetodite võrdlemisel kasutati erinevate füsikokeemiliste omadustega (nõrk hape versus nõrk alus, erinev lahustumiskiirus jne.) raviainet (nifedipiin, metoprolool, ibuprofeen) sisaldavaid preparaate. Rakendusuuringute raames võrreldi lisaks eri riikides toodetud mao- ja kaksteistsõrmiku haavandtõve ja südame-vereringehaiguste raviks kasutatavate preparaatide dissolutsiooniprofiile.
 
 
Lisainfo
meditsiinidoktor
Tartu Ülikool, 3. Juuni 1998

Jooksvad projektid

Juhendatud väitekirjad

Publikatsioonid

Klass
Aasta
Publikatsioon
 
1.1.
2013
Teder, Kersti; Pepeloshev, Andrei; Matto, Vallo; Meos, Andres (2013). Pharmacopoieal quality of non-expired and expired nifedipine formulations from Estonian and Russian Federation medicinal products market. Acta Poloniae Pharmaceutica Drug Research, 70 (3), 539−546.
3.2.
2013
Matto, Vallo; Meos, Andres (2013). In vitro dissolution of expired antibiotics. In: Menandez-Vilas, A (_EditorsAbbr). Microbial pathogens and strategies for combating them: science, technology and education. Volume 3 (1721−1725).. Badajoz, Hispaania: Formatex Research Center. (Microbiology Book Series).
6.6.
2013
Matto, Vallo (2013). Tartu Ülikooli farmaatsia instituudis toimus teaduskonverents "Future Performance Testing of Pharmaceuticals". Eesti Rohuteadlane, 20−21.
1.1.
2012
Remmel, I.; Vares, Lauri; Toom, Lauri; Matto, Vallo; Raal, Ain (2012). Phenolic compounds in five Epilobium species collected from Estonia. Natural Product Communications, 7 (10), 1323−1324.
1.1.
2012
Jürgenson, Siiri; Matto, Vallo; Raal, Ain (2012). Vegetational variation of phenolic compounds in Epilobium angustifolium. Natural Product Research, 26 (20), 1951−1953.10.1080/14786419.2011.643310.
1.1.
2012
Pudersell, Katrin; Vardja, Tõnis; Vardja, Rael; Matto, Vallo; Arak, Elmar; Raal, Ain (2012). Inorganic ions in the medium modify tropane alkaloids and riboflavin output in Hyoscyamus niger root cultures. Pharmacognosy Magazine, 73−77.
1.2.
2012
Raal, A.; Matto, V. (2012). Palatability perception of herbal teas: Impact of extraction time and saccharose. Journal of Medicinal Plants Research, 6 (12), 2514−2519.10.5897/JMPR12.042.
1.2.
2012
Meos, Andres; Matto, Vallo; Raal, Ain (2012). The impact of hedgerow to the lead content in plants cultivated adjacent to motorway. Journal of Research in Biology, 726−732.
1.1.
2011
Terasmaa, A.; Soomets, U.; Oflijan, J.; Punapart, M.; Hansen, M.; Matto, V.; Ehrlich, K.; Must, A.; Kõks, S.; Vasar, E. (2011). Wfs1 mutation makes mice sensitive to insulin-like effect of acute valproic acid and resistant to streptozocin. Journal of Physiology and Biochemistry, 67 (3), 381−390.10.1007/s13105-011-0088-0.
1.1.
2011
Meos, A.; Jüriado, T.; Matto, V.; Raal, A. (2011). Lead Content in Pot Marigold (Calendula officinalis L.) Inflorescences and Leaves: Impact of Precipitations and Vicinity of Motorway. Biological Trace Element Research, 244−251.10.1007/s12011-010-8689-y.
1.1.
2011
Matto, V; Terasmaa, A; Vasar, E; Kõks, S. (2011). Impaired striatal dopamine output of homozygous Wfs1 mutant mice in response to [K+] challenge. Journal of Physiology and Biochemistry, 67 (1), 53−60.
1.1.
2011
Innos, J.; Philips, M.-A.; Leidmaa, E.; Heinla, I.; Raud, S.; Reemann, P.; Plaas, M.; Nurk, K.; Kurrikoff, K.; Matto, V.; Visnapuu, T.; Mardi, P.; Kõks, S.; Vasar, E. (2011). Lower anxiety and a decrease in agonistic behaviour in Lsamp-deficient mice. Behavioural Brain Research, 217 (1), 21−31.10.1016/j.bbr.2010.09.019.
5.1.
2011
Teder, K.; Pepeloshev, A.; Matto, V.; Meos, A. (2011). PHARMACOPOEIAL QUALITY OF NON-EXPIRED AND EXPIRED NIFEDIPINE FORMULATIONS FROM ESTONIAN AND RUSSIAN FEDERATION MEDICINAL PRODUCTS MARKET. EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES, 44: Conference: 4th BBBB-Bled International Conference on Pharmaceutical Sciences - New Trends in Drug Discovery, Delivery Systems and Laboratory Diagnostics; Bled, Slovenia; SEP 29-OCT 01, 2011. 117−118.
6.3.
2011
Teder, K.; Matto, V.; Raal, A.; Volmer, D. (2011). Allergia. Apteeker, 4−11.
6.3.
2011
Teder, K.; Matto, V.; Raal, A.; Volmer, D. (2011). Erituselundkonna haigused. Apteeker, 13−18.
6.3.
2011
Teder, K.; Matto, V.; Raal, A.; Volmer, D. (2011). Alumise seedetrakti haigused. Apteeker, 12−23.
1.1.
2010
Paaver, Urve; Matto, Vallo; Raal, Ain (2010). Total tannin content in distinct Quercus robur L. galls. Journal of Medicinal Plants Research, 4 (8), 702−705.
3.1.
2010
Meos, A.; Matto, V. (2010). Pharmacopoeial Quality of Antimicrobial and Antiviral Formulations from Former Soviet Union Republics: Focus on Aciclovir. In: Mossillo, P.; Pinzini, J. (_EditorsAbbr). Biopharmaceutics and drug Hypersensitivity (165−176).. Nova Science Publishers.
6.3.
2010
Teder, K.i; Matto, V.; Raal, A.; Volmer, D. (2010). Koolitusartikkel: Peavalu. Apteeker, 16−22.
6.3.
2010
Teder, K.; Matto, V.; Raal, A., Volmer, D. (2010). Koolitusartikkel: Luu-, liigese- ja lihasevalu. Apteeker, 14−21.
6.3.
2010
Teder, K; Matto, V; Raal, A; Volmer, D. (2010). Maksa-, sapiteede ja pankreasehaigused. Apteeker, 8 (44), 13−22.
6.3.
2010
Teder, Kersti; Matto, Vallo; Raal, Ain; Volmer, Daisy (2010). Koolitusartikkel: Ülemise seedetrakti haigused. Apteeker, 13−24.
6.3.
2010
Teder, Kersti; Matto, Vallo; Raal, Ain; Volmer, Daisy (2010). Koolitusartikkel: Osteoporoos. Apteeker, 13−20.
5.2.
2009
Terasmaa A, Soomets A, Hansen M, Matto V, Vasar V, Kõks S. (2009). Acute valproic acid improves glucose tolerance in Wfs1 KO mice. European Journal of Pharmaceutical Sciences, S161−S163.
5.2.
2009
Matto V, Terasmaa A, Kõks S. (2009). Wfs1 KO and wild type mice differ in their striatl dopamine output in response to K+ but not morphine challenge. European Journal of Pharmaceutical Sciences, S158−S159.
6.3.
2009
Matto, V.; Volmer, D. (2009). 3. BBBB Rahvusvaheline Farmaatsiateaduste Konverents. Apteeker, 35-36, 37−40.
6.3.
2009
Teder, K.; Matto, V.; Raal, A.; Volmer, D. (2009). Täienduskoolitus: Kurguvalu. Apteeker, (35-36), 14−20.
6.3.
2009
Teder, K.; Matto, V.; Raal, A.; Volmer, D. (2009). Täiendkoolitus: Nohu. Apteeker, 14−23.
6.3.
2009
Teder, K.; Matto, V.; Raal, A.; Volmer, D. (2009). Koolitusartikkel: Köha. Apteeker, 14−22.
1.1.
2008
Bronnikova, O.; Matto, V.; Meos, A. (2008). Estonian and Russian Federation amoxicillin formulations: a comparative study of in vitro dissolution. Methods and Findings in Experimental and Clinical Pharmacology, 30 (5), 341−345.
1.1.
2008
Meos, A.; Paap, A.; Matto, V.; Veski, P. (2008). Comparative evaluation of quality of doxycycline formulations registered in Estonia to those registered in the Russian Federation. Drug Development Research, 69 (2), 58−68.10.1002/ddr.20228.
5.2.
2008
Paaver, U.; Lehto, T.; Matto, V.; Veski, P. (2008). Effect of non-ionic surfactants on the in vitro release of poorly soluble drugs.
5.1.
2007
Paaver, U.; Matto, V.; Veski, P. (2007). Effect of non-ionic surfactants on the dissolution of poorly soluble drugs. European Journal of Pharmaceutical Sciences, 32 (1), S34−S35.
5.1.
2007
Teder, K.; Matto, V.; Kreutzwald, P.; Meos, A. (2007). Dissolution of nifedipine from tablets: Formulations registered in Estonia compared to those produced in Russia and Ukraine. European Journal of Pharmaceutical Sciences, S48−S49.
5.1.
2007
Bronnikova, O.; Matto, V.; Meos, A. (2007). Comparative study of amoxicillin formulations registered in Estonia to those produced in Russia. European Journal of Pharmaceutical Sciences, S50−S50.
5.2.
2007
Paaver, U.; Matto, V.; Veski, P. (2007). Mitte-ioonsete pindaktiivsete ainete mõju halvastilahustuvate raviainete vabanemisele. Eesti Arst, 9, 670−671.
5.2.
2007
Meos, A.; Matto, V.; Trahhatšjova, A. (2007). Doksütsükliinipreparaatide kvaliteedi hindamine toimeaine vabanemise ja selle kvantitatiivse sisalduse alusel. Eesti Arst, 9, 706−707.
6.6.
2007
Matto, V. (2007). Tartu Ülikoolis toimus üleeuroopaline farmaatsiateaduste konverents. Eesti Rohuteadlane, 5, 22−24.
6.6.
2007
Veski, P.; Matto, V.; Raal, A.; Volmer, D.; Marvola, M.; Kristl, A.; Hincal, F. (2007). 2. BBBB Farmaatsiateaduste konverents Tartus 13-15.09.2007. Apteeker : ajakiri apteekritele ja arstidele, 4 (20), 37−41.
5.2.
2006
Teder, Kersti; Matto, Vallo; Kreutzwald, Piret; Meos, Andres (2006). Nifedipiini vabanemine tablettidest: Eestis registreeritud preparaatide võrdlus Vene Föderatsioonis ja Ukrainas toodetutega. Eesti Arst, 85 (9), 624−625.
1.2.
2005
Tani, P.; Lindberg, N.; Matto, V.; Appelberg, B.; NieminenvonWendt, T.; VonWendt, L.; Porkka-Heiskanen, T. (2005). Higher plasma ACTH levels in adults with Asperger syndrome. Journal of Psychosomatic Research , 58 (6), 533−536.
5.2.
2005
Wigren, H. M.; Matto, V.; Schepens, M.; Kalinchuk, A.; Stenberg, D.; Porkka-Heiskanen, T. (2005). Excitation of cells in the basal forebrain results in subsequent increase in sleep which resembles recovery sleep induced by sleep deprivation. SLEEP, 28 (65 Suppl.), 22.
5.1.
2003
Allikmets, L.; Vaarmann, A.; Matto, V. (2003). Anxiety in depression and antidepressants. European Neuropsychopharmacology, 13, S271−S271.
5.1.
2003
Allikmets, L.; Pruus, K.; Rudissaar, R.; Matto, V. (2003). Serotonin- and dopaminergic mechanisms of action of the atypical antipsychotics. European Journal of Pharmaceutical Sciences, 19, S22−S22.
5.1.
2003
Rudissaar, R.; Pruus, K.; Matto, V.; Allikmets, L. (2003). The effects of atypical antipsychotics on the apomorphine-induced aggressiveness and quipazine-induced wet dog shakes in rats. European Neuropsychopharmacology, 13, S352−S352.
5.2.
2003
Rudissaar, Ruth; Pruus, Katrin; Matto, Vallo; Allikmets, Lembit (2003). Atüüpiliste antipsühhootikumide toimed apomorfiini-indutseeritud agressiivsusele ja kvipasiin-indutseeritud pearaputustestile rottidel. Eesti Arst, 651.
6.7.
2003
Allikmets, L.; Matto, V. (2003). Estonian Society of Biological Psychiatry: Activity Report 2002. In: WFSBP.. Inglismaa.
1.1.
2002
Pruus, K.; Vaarmann, A.; Rudissaar, R.; Allikmets, L.; Matto, V. (2002). Role of 5-HT1A receptors in the mediation of acute citalopram effects - A 8-OH-DPAT challenge study. Progress in Neuro-Psychopharmacology & Biological Psychiatry, 26 (2), 227−232.
1.1.
2002
Pruus, K.; Rudisaar, R.; Vaarmann, A.; Matto, V.; Allikmets, L. (2002). 1-(1-naphthyl)-Piperazine, a mixed 5-HT1A and 5-HT2A/2C receptor ligand, elicits an anxiolytic-Like effect in the open-field test without changes in 5-HT metabolism. Methods and Findings in Experimental and Clinical Pharmacology, 24 (3), 151−157.
5.1.
2002
Allikmets, L.; Pruus, K.; Matto, V. (2002). Do the serotonin receptors mediate anxiogenic-like effect of antidepressants in rats? European Neuropsychopharmacology, 12, S190−S191.
5.1.
2002
Pruus, K.; Rudissaar, R.; Matto, V. (2002). Changes in the effects of antidepressants under the influence of agonists and antagonists of 5-HT1A receptors in rats. European Neuropsychopharmacology, 12, S191−S191.
5.2.
2002
Rudissaar, Ruth; Pruus, Katrin; Matto, Vallo; Allikmets, Lembit (2002). Atüüpiliste antipsühhootikumide toime seos 5-HT1A ja a-2adreno-retseptoritega käitumiskatsetes. Eesti Arst, 584.
5.2.
2002
Pruus, Katrin; Rudissaar, Ruth; Matto, Vallo; Allikmets, Lembit (2002). Serotoniini vabanemise muutused mõjustavad antidepressantide toimet. Eesti Arst, 579.
6.2.
2002
Žarkovskaja, T.; Pokk, P.; Kivastik, T.; Kalda, A.; Matto, V. (2002). Farmakoloogia harjutustestid. Tartu: Tartu Ülikool.
1.1.
2001
Rudissaar, R.; Pruus, K.; Vaarmann, A.; Pannell, P.; Skrebuhhova-Malmros, T.; Allikmets, L.; Matto, V. (2001). Acute trazodone and quipazine treatment attenuates apomorphine-induced aggressive behaviour in male rats without major impact on emotional behaviour or monoamine content post mortem. Pharmacological Research, 43 (4), 349−358.
1.1.
2001
Matto, V.; Vaarmann, A.; Allikmets, L. (2001). Apomorphine-induced aggressive behaviour in para-chlorophenylalanine-treated male rats: Implications to brain [H-3]Ketanserin binding and monoamine content. Pharmacology & Toxicology, 88 (3), 147−151.
1.1.
2001
Skrebuhhova-Malmros, T.; Allikmets, L.; Matto, V. (2001). Additive effect of clonidine and fluoxetine on apomorphine-induced aggressive behavior in adult male Wistar rats. Archives of Medical Research, 32 (3), 193−196.
1.2.
2001
Pruus, K.; Vaarmann, A.; Allikmets, L.; Matto, V. (2001). Single five-minutes forced swimming session is sufficient to decrease noradrenaline content in rat frontal cortex and hippocampus. Baltic Journal of Laboratory Animal Science, 11, 5−10.
1.2.
2001
Pruus, K.; Vaarmann, A.; Rudissaar, R.; Allikmets, L.; Matto, V. (2001). Acute antidepressant treatment has no major effect on post-mortem brain monoamine content in rats subjected to forced swimming test. Pharmaceutical and Pharmacological Letters, 91−94.
3.1.
2001
Allikmets, L.; Matto, V. (2001). Changes in brain monoaminergic systems in apomorphine-sensitized aggressive male Wistar rats. In: Martinez, M. (_EditorsAbbr). Prevention and Control of Aggression and the Impact on its Victims (45−50).. New York: Kluwer Academic / Plenum Publishers.
5.1.
2001
Allikmets, L.; Skrebuhhova-Malmros, T.; Pruus, K.; Matto, V. (2001). Effect of serotonin and GABAergic compounds on apomorphine-induced aggressive behavior in male rats. Aggressive Behavior, 27 (3), 203−203.
5.2.
2001
Matto, Vallo; Allikmets, Lembit (2001). 5-HT2 receptors in the effects of antidepressants. Eesti Arst, 55.
5.2.
2001
Skrebuhhova-Malmros, Tatjana; Pruus, Katrin; Matto, Vallo; Allikmets, Lembit (2001). The forced swimming test characterizes the anxiogenic - like effect of antidepressants. Eesti Arst, 61−62.
5.2.
2001
Matto, Vallo; Pruus, Katrin; Vaarmann, Annika; Allikmets, Lembit (2001). Kas kestva fluoksetiini manustamisejärgne serotoniini ringkäigu vähenemine rottidel on seotud 5-HT1A somatodendriitiliste autoretseptorite maharegulatsiooniga? Eesti Arst, 409.
5.2.
2001
Allikmets, Lembit; Matto, Vallo (2001). Serotoninergic system in the action of antidepressants. Eesti Arst, 10−11.
5.2.
2001
Pruus, Katrin; Skrebuhhova-Malmros, Tatjana; Rudissaar, Ruth; Matto, Vallo; Allikmets, Lembit (2001). The effects of antidepressants, 5-HT1A, 5-HT2A and 5-HT3 receptor ligands and their concomitant treatment on exploratory behaviour in the rat. Eesti Arst, 3, 58.
1.1.
2000
Rudissaar, R.; Pruus, K.; Skrebuhhova-Malmros, T.; Allikmets, L.; Matto, V. (2000). Involvement of GABAergic neurotransmission in the neurobiology of the apomorphine-induced aggressive behavior paradigm, a model of psychotic behavior in rats. Methods and Findings in Experimental and Clinical Pharmacology, 22 (8), 637−640.
1.1.
2000
Pruus, K.; Skrebuhhova-Malmros, T.; Rudissaar, R.; Matto, V.; Allikmets, L. (2000). 5-HT1A receptor agonists buspirone and gepirone attenuate apomorphine-induced aggressive behaviour in adult male Wistar rats. Journal of Physiology and Pharmacology, 51 (4), 833−846.
1.1.
2000
Pruus, K.; Rudissaar, R.; Skrebuhhova-Malmros, T.; Allikmets, L.; Matto, V. (2000). Development of apomorphine-induced aggressive behavior: Comparison of adult male and female Wistar rats. Methods and Findings in Experimental and Clinical Pharmacology, 22 (1), 47−50.
1.1.
2000
Skrebuhhova-Malmros, T.; Pruus, K.; Rudissaar, R.; Allikmets, L.; Matto, V. (2000). The serotonin 5-HT2A receptor subtype does not mediate apomorphine-induced aggressive behaviour in male Wister rats. Pharmacology Biochemistry and Behavior, 67 (2), 339−343.
1.1.
2000
Matto, V.; Vaarmann, A.; Rudissaar, R.; Pruus, K.; Skrebuhhova-Malmros, T.; Allikmets, L. (2000). Apomorphine-induced aggressive behaviour and post-mortem monoamine content in male Wistar rats. Neuroscience Letters, 289 (2), 131−134.
1.2.
2000
Matto, V.; Allikmets, L. (2000). Apomorphine-induced aggressive behaviour in adult male Wistar rats: a reliable model of psychotic behaviour. Baltic Journal of Laboratory Animal Science, 10, 175−180.
1.2.
2000
Matto, V.; Vaarmann, A.; Pruus, K.; Rudissaar, R.; Skrebuhhova-Malmros, T.; Allikmets, L. (2000). Moderately increased dopamine metabolism in apomorphine-aggressive adult male Wistar rats post mortem. Pharmaceutical and Pharmacological Letters, 10 (2), 59−62.
1.2.
2000
Pruus, K.; Rudissaar, R.; Skrebuhhova, T.; Allikmets, L.; Matto, V. (2000). Changes in [3H]citalopram binding in cerebral cortex after antidepressant treatment in monoamine-impaired rats. Bollettino Chimico Farmaceutico, 139 (1), 41−45.
1.3.
2000
Matto, Vallo; Vaarmann, Annika; Rudissaar, Ruth; Pruus, Katrin; Allikmets, Lembit (2000). Intensiivistunud post mortem dopamiinenergiline närviülekanne apomorfiinist põhjustatud agressiivsetel rottidel. Eesti Arst, 9, 549−550.
5.2.
2000
Pruus, K.; Rudissaar, R.; Skrebuhhova-Malmros, T.; Allikmets, L.; Matto, V. (2000). Serotonin 5-HT2a/2c and 5-HT3 Receptors Mediate The Exploratory Behaviour after Acute Antidepressant Administration in Rats. TRANSMITTERI, 2000 No 3, Suomen Farmakologiyhdistyksen jäsenlehti, 17. vuosikerta, THE FINNISH-ESTONIAN MEETING OF, NEUROPHARMACOLOGY: Viikki Biocenter; Helsinki, Finland; August 18-19, 2000. _EditorsAbbr Piepponen, T.P.
5.2.
2000
Matto, V.; Vaarmann, A.; Rudissaar, R.; Pruus, K.; Allikmets, L. (2000). Apomorphine-Induced Aggressive Behaviour in Adult Male Wistar Rats: Implication to Monoaminergic Neurotransmission. TRANSMITTERI, 2000 No 3, Suomen Farmakologiyhdistyksen jäsenlehti, 17. vuosikerta, THE FINNISH-ESTONIAN MEETING OF, NEUROPHARMACOLOGY: Viikki Biocenter; Helsinki, Finland; August 18-19, 2000. _EditorsAbbr Piepponen, T.P.
5.2.
2000
Allikmets, L.; Matto, V.; Pruus, K.; Sarv, H. (2000). Antidepressants and Serotonin Receptors. TRANSMITTERI, 2000 No 3, Suomen Farmakologiyhdistyksen jäsenlehti, 17. vuosikerta, THE FINNISH-ESTONIAN MEETING OF, NEUROPHARMACOLOGY: Viikki Biocenter; Helsinki, Finland; August 18-19, 2000. _EditorsAbbr Piepponen, T.P.
1.1.
1999
Rudissaar, R.; Pruus, K.; Skrebuhhova, T.; Allikmets, L.; Matto, V. (1999). Modulatory role of 5-HT3 receptors in the mediation of apomorphine-induced aggressive behaviour in male rats. Behavioural Brain Research, 106, 91−96.
1.1.
1999
Harro, J.; Haidkind, R.; Harro, M.; Modiri, AR.; Gillberg, PG.; Pahkla, R.; Matto, V.; Oreland, L. (1999). Chronic mild unpredictable stress after noradrenergic denervation: attenuation of behavioural and biochemical effects of DSP-4 treatment. European Neuropsychopharmacology, 10 (1), 5−16.
1.1.
1999
Matto, V.; Allikmets, L. (1999). Acute and chronic citalopram treatment differently modulates rat exploratory behavior in the exploration box test: No evidence for increased anxiety or changes in the [H-3]raclopride binding. Pharmacology, 58 (2), 59−69.
1.1.
1999
Skrebuhhova, T.; Allikmets, L.; Matto, V. (1999). Effects of anxiogenic drugs in rat forced swimming test. Methods and Findings in Experimental and Clinical Pharmacology, 21 (3), 173−178.
1.1.
1999
Skrebuhhova, T.; Allikmets, L.; Matto, V. (1999). 5-HT2A receptors mediate the effect of antidepressants in the elevated plus-maze test but have a partial role in the forced swimming test. Medical Science Research, 27 (4), 277−280.
1.1.
1999
Matto, V.; Skrebuhhova, T.; Allikmets, L. (1999). Apomorphine-induced upregulation of serotonin 5-HT2A receptors in male rats is independent from development of aggressive behaviour. Journal of Physiology and Pharmacology, 50 (2), 335−344.
1.1.
1999
Skrebuhhova, T.; Allikmets, L.; Matto, V. (1999). [H-3]-ketanserin binding and elevated plus-maze behavior after chronic antidepressant treatment in DSP-4 and P-CPA pretreated rats: Evidence for partial involvement of 5-HT2A receptors. Methods and Findings in Experimental and Clinical Pharmacology, 21 (7), 483−490.
1.1.
1999
Skrebuhhova-Malmros, T.; Allikmets, L.; Rudissaar, R.; Pruus, K.; Matto, V. (1999). Ondansetron fails to reverse antidepressant-elicited antiexploratory effects in the elevated plus-maze and open field tests. Medical Science Research, 27 (12), 835−837.
1.2.
1999
Skrebuhhova-Malmros, T.; Pruus, K.; Rudissaar, R.; Allikmets, L.; Matto, V. (1999). Modulation of forced swimming, open-field, and apomorphine-induced aggressive behaviour by 5-HT2A and 5-HT3 receptor ligands in male Wistar rats. Pharmaceutical and Pharmacological Letters, 9 (2), 70−73.
1.3.
1999
Rudissaar, R.; Pruus, K.; Skrebuhhova, T.; Allikmets, L.; Matto, V. (1999). 3H-tsitalopraami sidumine roti ajukoores DSP-4 ja p-CPA manustamise järgselt. Eesti Rohuteadlane, 1, 9−11.
5.2.
1999
Kask, A.; Rägo, L.; Pokk, P.; Matto, V.; Harro, J. (1999). Neuropeptide Y Y1 antagonist BIBP3226 is anxiogenic in dorsal periaqueductal gray. The International Journal of Neuropsychopharmacology, 2: 21st CINP Congress, Glasgow 1998. 187. (Suppl. 1).
5.2.
1999
Skrebuhhova, Tatjana; Allikmets, Lembit; Matto, Vallo (1999). [3H]ketanseriini sidumine DSP-4 ja p-CPA-d saanud rottide frontaal- ning tserebraalkoores p©Þrast kroonilist antidepressantide manustamist. TÜ Arstiteaduskonna Päevad, 6.-7. oktoober 1999. Tartu Ülikooli Kirjastus, 117.
5.2.
1999
Allikmets, Lembit; Matto, Vallo; Skrebuhhova, Tatjana (1999). Antidepressantide ja anksiogeenide toime võrdlus sundujumise (Porsolt') testis. TÜ Arstiteaduskonna Päevad, 6.-7.oktoober 1999, Tartu. TÜ Kirjastus, 15.
1.1.
1998
Lofberg, C.; Harro, J.; Matto, V.; Oreland, L. (1998). Cholecystokinin peptides and receptor binding in rat brain after DSP-4 treatment. Neuropeptides, 32 (2), 103−108.
1.1.
1998
Matto, V.; Skrebuhhova, T.; Allikmets, L. (1998). The effect of antidepressants on rat aggressive behavior in the electric footshock and apomorphine-induced aggressiveness paradigms. Methods and Findings in Experimental and Clinical Pharmacology, 20 (4), 329−337.
1.1.
1998
Matto, V.; Allikmets, L. (1998). Apomorphine-induced aggressive and nonaggressive rats differ in [H-3]raclopride-sensitive D-2 receptor binding characteristics. Medical Science Research, 26 (7), 499−501.
1.1.
1998
Matto, V.; Allikmets, L.; Skrebuhhova, T. (1998). Apomorphine-induced aggressiveness and [H-3]citalopram binding after antidepressant treatment in rats. Pharmacology Biochemistry and Behavior, 59 (3), 747−752.
1.2.
1998
Skrebuhhova, T.; Allikmets, L.; Matto, V. (1998). Functional integrity of [3H]raclopride-sensitive dopamine D2 and serotonin 5-HT2A receptors in rat brain after acute monoamine depletion. Pharmaceutical and Pharmacological Letters, 8 (4), 170−173.
1.2.
1998
Matto, V.; Allikmets, L. (1998). Rapid changes in the affinity of the 5-hydroxytryptamine transporter binding sites in rat frontal cortex after single citalopram injection. Pharmaceutical and Pharmacological Letters, 8 (2), 90−92.
1.2.
1998
Matto, V.; Allikmets, L. (1998). Comparison of rat exploratory behaviour after noradrenergic denervation in elevated zero-maze and open tests. Baltic Journal of Laboratory Animal Science, 8, 16−19.
1.2.
1998
Matto, V.; Allikmets, L. (1998). Rat exploratory behaviour after acute or repeated antidepressant treatment in open-field and exploration-box tests. Baltic Journal of Laboratory Animal Science, 8, 145−157.
2.3.
1998
Matto, Vallo (1998). Pharmacological studies on anxiogenic and antiaggressive properties of antidepressants. Tartu: Tartu University Press.
5.1.
1998
Allikmets, L.; Matto, V.; Skrebuhhova, T. (1998). Anxiogenics have similarities with antidepressants in forced swimming (Porsolt') test. Naunyn-Schmiedebergs Archives of Pharmacology, 358 (4), R765−R765.
1.1.
1997
Matto, V.; Harro, J.; Allikmets, L. (1997). The effect of drugs acting on CCK receptors and rat free exploration in the exploration box. Journal of Physiology and Pharmacology, 48 (2), 239−251.
1.1.
1997
Matto, V.; Harro, J.; Allikmets, L. (1997). The effects of cholecystokinin A and B receptor antagonists on exploratory behaviour in the elevated zero-maze in rat. Neuropharmacology, 36 (3), 389−396.
1.1.
1997
Otter, MH.; Matto, V.; Sõukand, R.; Skrebuhhova, T.; Allikmets, L.; Harro, J. (1997). Characterization of rat exploratory behavior using the exploration box test. Methods and Findings in Experimental and Clinical Pharmacology, 19 (10), 683−691.
1.1.
1997
Harro, J.; Lofberg, C.; Pahkla, R.; Matto, V.; Rago, L.; Oreland, L.; Allikmets, L. (1997). Different molecular forms of cholecystokinin and CCKB receptor binding in the rat brain after chronic antidepressant treatment. Naunyn-Schmiedebergs Archives of Pharmacology, 355 (1), 57−63.
3.1.
1997
Otter, M.; Skrebuhhova, T.; Matto, V.; Harro, J. (1997). Measurement of exploratory behaviour in rat. Harmonization of laboratory animal husbandry: 6th Symposium of the Federation of European Laboratory Animal Science Associations; Basel, Switzerland; 19.-21.06.1996. Ed. O’Donoghue, P.N. London: Royal Soc Medicine Press Ltd, 21−23.
5.1.
1997
Allikmets, L.; Matto, V. (1997). Do the antidepressants have antiaggressive effect? Naunyn-Schmiedebergs Archives of Pharmacology, 356 (4), 86−86.
1.1.
1996
Matto, V.; Harro, J.; Allikmets, L. (1996). The effects of cholecystokinin A and B receptor antagonists, devazepide and L 365260, on citalopram-induced decrease of exploratory behaviour in rat. Journal of Physiology and Pharmacology, 47 (4), 661−669.
5.1.
1996
Allikmets, L.; Matto, V.; Harro, J. (1996). Anxiogenic component in the mechanism of action of antidepressants is essential for clinical effect. Naunyn-Schmiedebergs Archives of Pharmacology, 354 (4), 143−143.
5.1.
1996
Matto, V.; Allikmets, L.; Harro, J. (1996). The effect of CCKA and CCKB receptor antagonists on rat exploratory behaviour in the elevated zero-maze. Naunyn-Schmiedebergs Archives of Pharmacology, 354 (4), 146−146.
5.1.
1996
Allikmets, L.; Matto, V.; Harro, J. (1996). Do the antidepressants have anxiogenic action? Biological Psychiatry, 39 (7), 433−433.
18.04.2019

Vallo Matto

https://www.etis.ee/CV/Vallo_Matto/eng
4.02.1969
737 5197
vallo.matto@ut.ee

Career

Institution(s) and position(s)
(1)1989-1991 and 1992-1993 Tartu University Clinics, Division of Child Psychiaty, hospital attendant
(2) 1993-1997 University of Tartu, Department of Pharmacology, senior laboratory assistant and teaching assistant (part-time)
(3) 1997-1998 University of Tartu, Department of Pharmacology, teaching assistant
(4) 1999 University of Tartu, Department of Pharmacology, senior teaching assistant
(5) 1999–2001 University of Tartu, Department of Pharmacology, extraordinary senior researcher (post-doc fellow)
(6) 2002 –2004 University of Tartu, Department of Pharmacology, senior teaching assistant
(7) 2003 University of Helsinki, researcher (neurophysiology)
(8) 2004-2005 University of Helsinki, senior researcher (neurophysiology)
01.09.2014–31.08.2015   
University of Tartu, Faculty of Medicine, Department of Pharmacy, Senior Research Fellow in Pharmacy (0,25)
01.09.2010–31.08.2014   
University of Tartu, Faculty of Medicine, Department of Pharmacy, Senior Research Fellow in Pharmacy (1,00)
2005–2005   
University of Tartu, Faculty of Medicine, Department of Pharmacy, erakorraline vanemteadur (1,00)
2005–31.08.2010   
University of Tartu, Faculty of Medicine, Department of Pharmacy, Chair of Pharmaceutical Technology and Biopharmaceutics, Senior Researcher (1,00)
 
 
Education
(1) 1976-1987 Tallinn 42th Secondary School, pupil
(2) September 1987 - June 1991 University of Tartu, Faculty of Medicine, student
(3) August 1991- January 1992 University of Helsinki, Faculty of Medicine, student
(4) January 1992 - June 1993 University of Tartu, Faculty of Medicine, student
(5) June 1993 - University of Tartu graduate, M.D.
(6) September 1993 - January 1998 University of Tartu, Department of Pharmacology, Ph.D. student
(7) June 3rd, 1998, University of Tartu, Dr. med.
 
 
R&D related managerial and administrative work
2007−2007   
(3) 2nd BBBB Conference on Pharmaceutical Sciences (September, 2007), Scientific Secretary
2001−2001   
(2) 2nd Baltic Regional Meeting of Biological Psychiatry (May-June, 2001) Secretary of the Orginizing Committee
1995−1995   
(1) Rudolf Buchheim Conference in Neuropharmacology (May, 1995) Member of the Orginizing Committee

Qualifications

Academic degrees
Vallo Matto, Doctor's Degree, 1998, (sup) Lembit Allikmets, Pharmacological studies on anxiogenic and antiaggressive properties of antidepressants, University of Tartu, Faculty of Medicine.
 
 
Honours & awards
2004, Vallo Matto, ESRS Poster Prize, Prague, October 2004, European Sleep Research Society 17th Congress
2001, Vallo Matto, WFSBP Young Investigator Travel Award 2001
2000, Vallo Matto, European College of Neuropsychopharmacology (ECNP) Fellowship Award, 2000
2000, Vallo Matto, 1st Baltic Regional Meeting in Biological Psychiatry, WFSBP 1st Poster Prize, Vilnius, Lithuania, 2000
1998, Vallo Matto, Lundbeck Eesti AS 1998 award in biological psychiatry (with MSc. Tatjana Skrebuhhova-Malmros)
1997, Vallo Matto, “Ants and Maria Silvere and Sigfried Pant Memorial Scholarship at Tartu University Foundation” scholarship, 1997
1997, Vallo Matto, The European Neuropeptide Club Award, 1997
1997, Vallo Matto, 3rd Prize of the students competition organized by the Ministry of Education, Republic of Estonia, 1997
 
 
Field of research
FIELD OF RESEARCH: 3. Health; 3.3. Pharmacy; SPECIALITY: Present research topics: Studies on the chemical, physicochemical, and biopharmaceutical properties of drug delivery systems (DDS): estimation and improvement of quality, PI Prof. P. Veski. The project covers the development of improved analysis methods for solid extended release DDS and investigations of the dissolution profiles of DDS manufactured in different countries (with emphasis on the DDS used for the treatment of gastro-intestinal ulcer and cardio-vascular diseases).
 
 
Additional information
Doctor of Medical Sciences (Dr. Med.)
University of Tartu, June 3rd, 1998

Projects in progress

Supervised dissertations

Publications

Category
Year
Publication
 
1.1.
2013
Teder, Kersti; Pepeloshev, Andrei; Matto, Vallo; Meos, Andres (2013). Pharmacopoieal quality of non-expired and expired nifedipine formulations from Estonian and Russian Federation medicinal products market. Acta Poloniae Pharmaceutica Drug Research, 70 (3), 539−546.
3.2.
2013
Matto, Vallo; Meos, Andres (2013). In vitro dissolution of expired antibiotics. In: Menandez-Vilas, A (_EditorsAbbr). Microbial pathogens and strategies for combating them: science, technology and education. Volume 3 (1721−1725).. Badajoz, Hispaania: Formatex Research Center. (Microbiology Book Series).
6.6.
2013
Matto, Vallo (2013). Tartu Ülikooli farmaatsia instituudis toimus teaduskonverents "Future Performance Testing of Pharmaceuticals". Eesti Rohuteadlane, 20−21.
1.1.
2012
Remmel, I.; Vares, Lauri; Toom, Lauri; Matto, Vallo; Raal, Ain (2012). Phenolic compounds in five Epilobium species collected from Estonia. Natural Product Communications, 7 (10), 1323−1324.
1.1.
2012
Jürgenson, Siiri; Matto, Vallo; Raal, Ain (2012). Vegetational variation of phenolic compounds in Epilobium angustifolium. Natural Product Research, 26 (20), 1951−1953.10.1080/14786419.2011.643310.
1.1.
2012
Pudersell, Katrin; Vardja, Tõnis; Vardja, Rael; Matto, Vallo; Arak, Elmar; Raal, Ain (2012). Inorganic ions in the medium modify tropane alkaloids and riboflavin output in Hyoscyamus niger root cultures. Pharmacognosy Magazine, 73−77.
1.2.
2012
Raal, A.; Matto, V. (2012). Palatability perception of herbal teas: Impact of extraction time and saccharose. Journal of Medicinal Plants Research, 6 (12), 2514−2519.10.5897/JMPR12.042.
1.2.
2012
Meos, Andres; Matto, Vallo; Raal, Ain (2012). The impact of hedgerow to the lead content in plants cultivated adjacent to motorway. Journal of Research in Biology, 726−732.
1.1.
2011
Terasmaa, A.; Soomets, U.; Oflijan, J.; Punapart, M.; Hansen, M.; Matto, V.; Ehrlich, K.; Must, A.; Kõks, S.; Vasar, E. (2011). Wfs1 mutation makes mice sensitive to insulin-like effect of acute valproic acid and resistant to streptozocin. Journal of Physiology and Biochemistry, 67 (3), 381−390.10.1007/s13105-011-0088-0.
1.1.
2011
Meos, A.; Jüriado, T.; Matto, V.; Raal, A. (2011). Lead Content in Pot Marigold (Calendula officinalis L.) Inflorescences and Leaves: Impact of Precipitations and Vicinity of Motorway. Biological Trace Element Research, 244−251.10.1007/s12011-010-8689-y.
1.1.
2011
Matto, V; Terasmaa, A; Vasar, E; Kõks, S. (2011). Impaired striatal dopamine output of homozygous Wfs1 mutant mice in response to [K+] challenge. Journal of Physiology and Biochemistry, 67 (1), 53−60.
1.1.
2011
Innos, J.; Philips, M.-A.; Leidmaa, E.; Heinla, I.; Raud, S.; Reemann, P.; Plaas, M.; Nurk, K.; Kurrikoff, K.; Matto, V.; Visnapuu, T.; Mardi, P.; Kõks, S.; Vasar, E. (2011). Lower anxiety and a decrease in agonistic behaviour in Lsamp-deficient mice. Behavioural Brain Research, 217 (1), 21−31.10.1016/j.bbr.2010.09.019.
5.1.
2011
Teder, K.; Pepeloshev, A.; Matto, V.; Meos, A. (2011). PHARMACOPOEIAL QUALITY OF NON-EXPIRED AND EXPIRED NIFEDIPINE FORMULATIONS FROM ESTONIAN AND RUSSIAN FEDERATION MEDICINAL PRODUCTS MARKET. EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES, 44: Conference: 4th BBBB-Bled International Conference on Pharmaceutical Sciences - New Trends in Drug Discovery, Delivery Systems and Laboratory Diagnostics; Bled, Slovenia; SEP 29-OCT 01, 2011. 117−118.
6.3.
2011
Teder, K.; Matto, V.; Raal, A.; Volmer, D. (2011). Allergia. Apteeker, 4−11.
6.3.
2011
Teder, K.; Matto, V.; Raal, A.; Volmer, D. (2011). Erituselundkonna haigused. Apteeker, 13−18.
6.3.
2011
Teder, K.; Matto, V.; Raal, A.; Volmer, D. (2011). Alumise seedetrakti haigused. Apteeker, 12−23.
1.1.
2010
Paaver, Urve; Matto, Vallo; Raal, Ain (2010). Total tannin content in distinct Quercus robur L. galls. Journal of Medicinal Plants Research, 4 (8), 702−705.
3.1.
2010
Meos, A.; Matto, V. (2010). Pharmacopoeial Quality of Antimicrobial and Antiviral Formulations from Former Soviet Union Republics: Focus on Aciclovir. In: Mossillo, P.; Pinzini, J. (_EditorsAbbr). Biopharmaceutics and drug Hypersensitivity (165−176).. Nova Science Publishers.
6.3.
2010
Teder, K.i; Matto, V.; Raal, A.; Volmer, D. (2010). Koolitusartikkel: Peavalu. Apteeker, 16−22.
6.3.
2010
Teder, K.; Matto, V.; Raal, A., Volmer, D. (2010). Koolitusartikkel: Luu-, liigese- ja lihasevalu. Apteeker, 14−21.
6.3.
2010
Teder, K; Matto, V; Raal, A; Volmer, D. (2010). Maksa-, sapiteede ja pankreasehaigused. Apteeker, 8 (44), 13−22.
6.3.
2010
Teder, Kersti; Matto, Vallo; Raal, Ain; Volmer, Daisy (2010). Koolitusartikkel: Ülemise seedetrakti haigused. Apteeker, 13−24.
6.3.
2010
Teder, Kersti; Matto, Vallo; Raal, Ain; Volmer, Daisy (2010). Koolitusartikkel: Osteoporoos. Apteeker, 13−20.
5.2.
2009
Terasmaa A, Soomets A, Hansen M, Matto V, Vasar V, Kõks S. (2009). Acute valproic acid improves glucose tolerance in Wfs1 KO mice. European Journal of Pharmaceutical Sciences, S161−S163.
5.2.
2009
Matto V, Terasmaa A, Kõks S. (2009). Wfs1 KO and wild type mice differ in their striatl dopamine output in response to K+ but not morphine challenge. European Journal of Pharmaceutical Sciences, S158−S159.
6.3.
2009
Matto, V.; Volmer, D. (2009). 3. BBBB Rahvusvaheline Farmaatsiateaduste Konverents. Apteeker, 35-36, 37−40.
6.3.
2009
Teder, K.; Matto, V.; Raal, A.; Volmer, D. (2009). Täienduskoolitus: Kurguvalu. Apteeker, (35-36), 14−20.
6.3.
2009
Teder, K.; Matto, V.; Raal, A.; Volmer, D. (2009). Täiendkoolitus: Nohu. Apteeker, 14−23.
6.3.
2009
Teder, K.; Matto, V.; Raal, A.; Volmer, D. (2009). Koolitusartikkel: Köha. Apteeker, 14−22.
1.1.
2008
Bronnikova, O.; Matto, V.; Meos, A. (2008). Estonian and Russian Federation amoxicillin formulations: a comparative study of in vitro dissolution. Methods and Findings in Experimental and Clinical Pharmacology, 30 (5), 341−345.
1.1.
2008
Meos, A.; Paap, A.; Matto, V.; Veski, P. (2008). Comparative evaluation of quality of doxycycline formulations registered in Estonia to those registered in the Russian Federation. Drug Development Research, 69 (2), 58−68.10.1002/ddr.20228.
5.2.
2008
Paaver, U.; Lehto, T.; Matto, V.; Veski, P. (2008). Effect of non-ionic surfactants on the in vitro release of poorly soluble drugs.
5.1.
2007
Paaver, U.; Matto, V.; Veski, P. (2007). Effect of non-ionic surfactants on the dissolution of poorly soluble drugs. European Journal of Pharmaceutical Sciences, 32 (1), S34−S35.
5.1.
2007
Teder, K.; Matto, V.; Kreutzwald, P.; Meos, A. (2007). Dissolution of nifedipine from tablets: Formulations registered in Estonia compared to those produced in Russia and Ukraine. European Journal of Pharmaceutical Sciences, S48−S49.
5.1.
2007
Bronnikova, O.; Matto, V.; Meos, A. (2007). Comparative study of amoxicillin formulations registered in Estonia to those produced in Russia. European Journal of Pharmaceutical Sciences, S50−S50.
5.2.
2007
Paaver, U.; Matto, V.; Veski, P. (2007). Mitte-ioonsete pindaktiivsete ainete mõju halvastilahustuvate raviainete vabanemisele. Eesti Arst, 9, 670−671.
5.2.
2007
Meos, A.; Matto, V.; Trahhatšjova, A. (2007). Doksütsükliinipreparaatide kvaliteedi hindamine toimeaine vabanemise ja selle kvantitatiivse sisalduse alusel. Eesti Arst, 9, 706−707.
6.6.
2007
Matto, V. (2007). Tartu Ülikoolis toimus üleeuroopaline farmaatsiateaduste konverents. Eesti Rohuteadlane, 5, 22−24.
6.6.
2007
Veski, P.; Matto, V.; Raal, A.; Volmer, D.; Marvola, M.; Kristl, A.; Hincal, F. (2007). 2. BBBB Farmaatsiateaduste konverents Tartus 13-15.09.2007. Apteeker : ajakiri apteekritele ja arstidele, 4 (20), 37−41.
5.2.
2006
Teder, Kersti; Matto, Vallo; Kreutzwald, Piret; Meos, Andres (2006). Nifedipiini vabanemine tablettidest: Eestis registreeritud preparaatide võrdlus Vene Föderatsioonis ja Ukrainas toodetutega. Eesti Arst, 85 (9), 624−625.
1.2.
2005
Tani, P.; Lindberg, N.; Matto, V.; Appelberg, B.; NieminenvonWendt, T.; VonWendt, L.; Porkka-Heiskanen, T. (2005). Higher plasma ACTH levels in adults with Asperger syndrome. Journal of Psychosomatic Research , 58 (6), 533−536.
5.2.
2005
Wigren, H. M.; Matto, V.; Schepens, M.; Kalinchuk, A.; Stenberg, D.; Porkka-Heiskanen, T. (2005). Excitation of cells in the basal forebrain results in subsequent increase in sleep which resembles recovery sleep induced by sleep deprivation. SLEEP, 28 (65 Suppl.), 22.
5.1.
2003
Allikmets, L.; Vaarmann, A.; Matto, V. (2003). Anxiety in depression and antidepressants. European Neuropsychopharmacology, 13, S271−S271.
5.1.
2003
Allikmets, L.; Pruus, K.; Rudissaar, R.; Matto, V. (2003). Serotonin- and dopaminergic mechanisms of action of the atypical antipsychotics. European Journal of Pharmaceutical Sciences, 19, S22−S22.
5.1.
2003
Rudissaar, R.; Pruus, K.; Matto, V.; Allikmets, L. (2003). The effects of atypical antipsychotics on the apomorphine-induced aggressiveness and quipazine-induced wet dog shakes in rats. European Neuropsychopharmacology, 13, S352−S352.
5.2.
2003
Rudissaar, Ruth; Pruus, Katrin; Matto, Vallo; Allikmets, Lembit (2003). Atüüpiliste antipsühhootikumide toimed apomorfiini-indutseeritud agressiivsusele ja kvipasiin-indutseeritud pearaputustestile rottidel. Eesti Arst, 651.
6.7.
2003
Allikmets, L.; Matto, V. (2003). Estonian Society of Biological Psychiatry: Activity Report 2002. In: WFSBP.. Inglismaa.
1.1.
2002
Pruus, K.; Vaarmann, A.; Rudissaar, R.; Allikmets, L.; Matto, V. (2002). Role of 5-HT1A receptors in the mediation of acute citalopram effects - A 8-OH-DPAT challenge study. Progress in Neuro-Psychopharmacology & Biological Psychiatry, 26 (2), 227−232.
1.1.
2002
Pruus, K.; Rudisaar, R.; Vaarmann, A.; Matto, V.; Allikmets, L. (2002). 1-(1-naphthyl)-Piperazine, a mixed 5-HT1A and 5-HT2A/2C receptor ligand, elicits an anxiolytic-Like effect in the open-field test without changes in 5-HT metabolism. Methods and Findings in Experimental and Clinical Pharmacology, 24 (3), 151−157.
5.1.
2002
Allikmets, L.; Pruus, K.; Matto, V. (2002). Do the serotonin receptors mediate anxiogenic-like effect of antidepressants in rats? European Neuropsychopharmacology, 12, S190−S191.
5.1.
2002
Pruus, K.; Rudissaar, R.; Matto, V. (2002). Changes in the effects of antidepressants under the influence of agonists and antagonists of 5-HT1A receptors in rats. European Neuropsychopharmacology, 12, S191−S191.
5.2.
2002
Rudissaar, Ruth; Pruus, Katrin; Matto, Vallo; Allikmets, Lembit (2002). Atüüpiliste antipsühhootikumide toime seos 5-HT1A ja a-2adreno-retseptoritega käitumiskatsetes. Eesti Arst, 584.
5.2.
2002
Pruus, Katrin; Rudissaar, Ruth; Matto, Vallo; Allikmets, Lembit (2002). Serotoniini vabanemise muutused mõjustavad antidepressantide toimet. Eesti Arst, 579.
6.2.
2002
Žarkovskaja, T.; Pokk, P.; Kivastik, T.; Kalda, A.; Matto, V. (2002). Farmakoloogia harjutustestid. Tartu: Tartu Ülikool.
1.1.
2001
Rudissaar, R.; Pruus, K.; Vaarmann, A.; Pannell, P.; Skrebuhhova-Malmros, T.; Allikmets, L.; Matto, V. (2001). Acute trazodone and quipazine treatment attenuates apomorphine-induced aggressive behaviour in male rats without major impact on emotional behaviour or monoamine content post mortem. Pharmacological Research, 43 (4), 349−358.
1.1.
2001
Matto, V.; Vaarmann, A.; Allikmets, L. (2001). Apomorphine-induced aggressive behaviour in para-chlorophenylalanine-treated male rats: Implications to brain [H-3]Ketanserin binding and monoamine content. Pharmacology & Toxicology, 88 (3), 147−151.
1.1.
2001
Skrebuhhova-Malmros, T.; Allikmets, L.; Matto, V. (2001). Additive effect of clonidine and fluoxetine on apomorphine-induced aggressive behavior in adult male Wistar rats. Archives of Medical Research, 32 (3), 193−196.
1.2.
2001
Pruus, K.; Vaarmann, A.; Allikmets, L.; Matto, V. (2001). Single five-minutes forced swimming session is sufficient to decrease noradrenaline content in rat frontal cortex and hippocampus. Baltic Journal of Laboratory Animal Science, 11, 5−10.
1.2.
2001
Pruus, K.; Vaarmann, A.; Rudissaar, R.; Allikmets, L.; Matto, V. (2001). Acute antidepressant treatment has no major effect on post-mortem brain monoamine content in rats subjected to forced swimming test. Pharmaceutical and Pharmacological Letters, 91−94.
3.1.
2001
Allikmets, L.; Matto, V. (2001). Changes in brain monoaminergic systems in apomorphine-sensitized aggressive male Wistar rats. In: Martinez, M. (_EditorsAbbr). Prevention and Control of Aggression and the Impact on its Victims (45−50).. New York: Kluwer Academic / Plenum Publishers.
5.1.
2001
Allikmets, L.; Skrebuhhova-Malmros, T.; Pruus, K.; Matto, V. (2001). Effect of serotonin and GABAergic compounds on apomorphine-induced aggressive behavior in male rats. Aggressive Behavior, 27 (3), 203−203.
5.2.
2001
Matto, Vallo; Allikmets, Lembit (2001). 5-HT2 receptors in the effects of antidepressants. Eesti Arst, 55.
5.2.
2001
Skrebuhhova-Malmros, Tatjana; Pruus, Katrin; Matto, Vallo; Allikmets, Lembit (2001). The forced swimming test characterizes the anxiogenic - like effect of antidepressants. Eesti Arst, 61−62.
5.2.
2001
Matto, Vallo; Pruus, Katrin; Vaarmann, Annika; Allikmets, Lembit (2001). Kas kestva fluoksetiini manustamisejärgne serotoniini ringkäigu vähenemine rottidel on seotud 5-HT1A somatodendriitiliste autoretseptorite maharegulatsiooniga? Eesti Arst, 409.
5.2.
2001
Allikmets, Lembit; Matto, Vallo (2001). Serotoninergic system in the action of antidepressants. Eesti Arst, 10−11.
5.2.
2001
Pruus, Katrin; Skrebuhhova-Malmros, Tatjana; Rudissaar, Ruth; Matto, Vallo; Allikmets, Lembit (2001). The effects of antidepressants, 5-HT1A, 5-HT2A and 5-HT3 receptor ligands and their concomitant treatment on exploratory behaviour in the rat. Eesti Arst, 3, 58.
1.1.
2000
Rudissaar, R.; Pruus, K.; Skrebuhhova-Malmros, T.; Allikmets, L.; Matto, V. (2000). Involvement of GABAergic neurotransmission in the neurobiology of the apomorphine-induced aggressive behavior paradigm, a model of psychotic behavior in rats. Methods and Findings in Experimental and Clinical Pharmacology, 22 (8), 637−640.
1.1.
2000
Pruus, K.; Skrebuhhova-Malmros, T.; Rudissaar, R.; Matto, V.; Allikmets, L. (2000). 5-HT1A receptor agonists buspirone and gepirone attenuate apomorphine-induced aggressive behaviour in adult male Wistar rats. Journal of Physiology and Pharmacology, 51 (4), 833−846.
1.1.
2000
Pruus, K.; Rudissaar, R.; Skrebuhhova-Malmros, T.; Allikmets, L.; Matto, V. (2000). Development of apomorphine-induced aggressive behavior: Comparison of adult male and female Wistar rats. Methods and Findings in Experimental and Clinical Pharmacology, 22 (1), 47−50.
1.1.
2000
Skrebuhhova-Malmros, T.; Pruus, K.; Rudissaar, R.; Allikmets, L.; Matto, V. (2000). The serotonin 5-HT2A receptor subtype does not mediate apomorphine-induced aggressive behaviour in male Wister rats. Pharmacology Biochemistry and Behavior, 67 (2), 339−343.
1.1.
2000
Matto, V.; Vaarmann, A.; Rudissaar, R.; Pruus, K.; Skrebuhhova-Malmros, T.; Allikmets, L. (2000). Apomorphine-induced aggressive behaviour and post-mortem monoamine content in male Wistar rats. Neuroscience Letters, 289 (2), 131−134.
1.2.
2000
Matto, V.; Allikmets, L. (2000). Apomorphine-induced aggressive behaviour in adult male Wistar rats: a reliable model of psychotic behaviour. Baltic Journal of Laboratory Animal Science, 10, 175−180.
1.2.
2000
Matto, V.; Vaarmann, A.; Pruus, K.; Rudissaar, R.; Skrebuhhova-Malmros, T.; Allikmets, L. (2000). Moderately increased dopamine metabolism in apomorphine-aggressive adult male Wistar rats post mortem. Pharmaceutical and Pharmacological Letters, 10 (2), 59−62.
1.2.
2000
Pruus, K.; Rudissaar, R.; Skrebuhhova, T.; Allikmets, L.; Matto, V. (2000). Changes in [3H]citalopram binding in cerebral cortex after antidepressant treatment in monoamine-impaired rats. Bollettino Chimico Farmaceutico, 139 (1), 41−45.
1.3.
2000
Matto, Vallo; Vaarmann, Annika; Rudissaar, Ruth; Pruus, Katrin; Allikmets, Lembit (2000). Intensiivistunud post mortem dopamiinenergiline närviülekanne apomorfiinist põhjustatud agressiivsetel rottidel. Eesti Arst, 9, 549−550.
5.2.
2000
Pruus, K.; Rudissaar, R.; Skrebuhhova-Malmros, T.; Allikmets, L.; Matto, V. (2000). Serotonin 5-HT2a/2c and 5-HT3 Receptors Mediate The Exploratory Behaviour after Acute Antidepressant Administration in Rats. TRANSMITTERI, 2000 No 3, Suomen Farmakologiyhdistyksen jäsenlehti, 17. vuosikerta, THE FINNISH-ESTONIAN MEETING OF, NEUROPHARMACOLOGY: Viikki Biocenter; Helsinki, Finland; August 18-19, 2000. _EditorsAbbr Piepponen, T.P.
5.2.
2000
Matto, V.; Vaarmann, A.; Rudissaar, R.; Pruus, K.; Allikmets, L. (2000). Apomorphine-Induced Aggressive Behaviour in Adult Male Wistar Rats: Implication to Monoaminergic Neurotransmission. TRANSMITTERI, 2000 No 3, Suomen Farmakologiyhdistyksen jäsenlehti, 17. vuosikerta, THE FINNISH-ESTONIAN MEETING OF, NEUROPHARMACOLOGY: Viikki Biocenter; Helsinki, Finland; August 18-19, 2000. _EditorsAbbr Piepponen, T.P.
5.2.
2000
Allikmets, L.; Matto, V.; Pruus, K.; Sarv, H. (2000). Antidepressants and Serotonin Receptors. TRANSMITTERI, 2000 No 3, Suomen Farmakologiyhdistyksen jäsenlehti, 17. vuosikerta, THE FINNISH-ESTONIAN MEETING OF, NEUROPHARMACOLOGY: Viikki Biocenter; Helsinki, Finland; August 18-19, 2000. _EditorsAbbr Piepponen, T.P.
1.1.
1999
Rudissaar, R.; Pruus, K.; Skrebuhhova, T.; Allikmets, L.; Matto, V. (1999). Modulatory role of 5-HT3 receptors in the mediation of apomorphine-induced aggressive behaviour in male rats. Behavioural Brain Research, 106, 91−96.
1.1.
1999
Harro, J.; Haidkind, R.; Harro, M.; Modiri, AR.; Gillberg, PG.; Pahkla, R.; Matto, V.; Oreland, L. (1999). Chronic mild unpredictable stress after noradrenergic denervation: attenuation of behavioural and biochemical effects of DSP-4 treatment. European Neuropsychopharmacology, 10 (1), 5−16.
1.1.
1999
Matto, V.; Allikmets, L. (1999). Acute and chronic citalopram treatment differently modulates rat exploratory behavior in the exploration box test: No evidence for increased anxiety or changes in the [H-3]raclopride binding. Pharmacology, 58 (2), 59−69.
1.1.
1999
Skrebuhhova, T.; Allikmets, L.; Matto, V. (1999). Effects of anxiogenic drugs in rat forced swimming test. Methods and Findings in Experimental and Clinical Pharmacology, 21 (3), 173−178.
1.1.
1999
Skrebuhhova, T.; Allikmets, L.; Matto, V. (1999). 5-HT2A receptors mediate the effect of antidepressants in the elevated plus-maze test but have a partial role in the forced swimming test. Medical Science Research, 27 (4), 277−280.
1.1.
1999
Matto, V.; Skrebuhhova, T.; Allikmets, L. (1999). Apomorphine-induced upregulation of serotonin 5-HT2A receptors in male rats is independent from development of aggressive behaviour. Journal of Physiology and Pharmacology, 50 (2), 335−344.
1.1.
1999
Skrebuhhova, T.; Allikmets, L.; Matto, V. (1999). [H-3]-ketanserin binding and elevated plus-maze behavior after chronic antidepressant treatment in DSP-4 and P-CPA pretreated rats: Evidence for partial involvement of 5-HT2A receptors. Methods and Findings in Experimental and Clinical Pharmacology, 21 (7), 483−490.
1.1.
1999
Skrebuhhova-Malmros, T.; Allikmets, L.; Rudissaar, R.; Pruus, K.; Matto, V. (1999). Ondansetron fails to reverse antidepressant-elicited antiexploratory effects in the elevated plus-maze and open field tests. Medical Science Research, 27 (12), 835−837.
1.2.
1999
Skrebuhhova-Malmros, T.; Pruus, K.; Rudissaar, R.; Allikmets, L.; Matto, V. (1999). Modulation of forced swimming, open-field, and apomorphine-induced aggressive behaviour by 5-HT2A and 5-HT3 receptor ligands in male Wistar rats. Pharmaceutical and Pharmacological Letters, 9 (2), 70−73.
1.3.
1999
Rudissaar, R.; Pruus, K.; Skrebuhhova, T.; Allikmets, L.; Matto, V. (1999). 3H-tsitalopraami sidumine roti ajukoores DSP-4 ja p-CPA manustamise järgselt. Eesti Rohuteadlane, 1, 9−11.
5.2.
1999
Kask, A.; Rägo, L.; Pokk, P.; Matto, V.; Harro, J. (1999). Neuropeptide Y Y1 antagonist BIBP3226 is anxiogenic in dorsal periaqueductal gray. The International Journal of Neuropsychopharmacology, 2: 21st CINP Congress, Glasgow 1998. 187. (Suppl. 1).
5.2.
1999
Skrebuhhova, Tatjana; Allikmets, Lembit; Matto, Vallo (1999). [3H]ketanseriini sidumine DSP-4 ja p-CPA-d saanud rottide frontaal- ning tserebraalkoores p©Þrast kroonilist antidepressantide manustamist. TÜ Arstiteaduskonna Päevad, 6.-7. oktoober 1999. Tartu Ülikooli Kirjastus, 117.
5.2.
1999
Allikmets, Lembit; Matto, Vallo; Skrebuhhova, Tatjana (1999). Antidepressantide ja anksiogeenide toime võrdlus sundujumise (Porsolt') testis. TÜ Arstiteaduskonna Päevad, 6.-7.oktoober 1999, Tartu. TÜ Kirjastus, 15.
1.1.
1998
Lofberg, C.; Harro, J.; Matto, V.; Oreland, L. (1998). Cholecystokinin peptides and receptor binding in rat brain after DSP-4 treatment. Neuropeptides, 32 (2), 103−108.
1.1.
1998
Matto, V.; Skrebuhhova, T.; Allikmets, L. (1998). The effect of antidepressants on rat aggressive behavior in the electric footshock and apomorphine-induced aggressiveness paradigms. Methods and Findings in Experimental and Clinical Pharmacology, 20 (4), 329−337.
1.1.
1998
Matto, V.; Allikmets, L. (1998). Apomorphine-induced aggressive and nonaggressive rats differ in [H-3]raclopride-sensitive D-2 receptor binding characteristics. Medical Science Research, 26 (7), 499−501.
1.1.
1998
Matto, V.; Allikmets, L.; Skrebuhhova, T. (1998). Apomorphine-induced aggressiveness and [H-3]citalopram binding after antidepressant treatment in rats. Pharmacology Biochemistry and Behavior, 59 (3), 747−752.
1.2.
1998
Skrebuhhova, T.; Allikmets, L.; Matto, V. (1998). Functional integrity of [3H]raclopride-sensitive dopamine D2 and serotonin 5-HT2A receptors in rat brain after acute monoamine depletion. Pharmaceutical and Pharmacological Letters, 8 (4), 170−173.
1.2.
1998
Matto, V.; Allikmets, L. (1998). Rapid changes in the affinity of the 5-hydroxytryptamine transporter binding sites in rat frontal cortex after single citalopram injection. Pharmaceutical and Pharmacological Letters, 8 (2), 90−92.
1.2.
1998
Matto, V.; Allikmets, L. (1998). Comparison of rat exploratory behaviour after noradrenergic denervation in elevated zero-maze and open tests. Baltic Journal of Laboratory Animal Science, 8, 16−19.
1.2.
1998
Matto, V.; Allikmets, L. (1998). Rat exploratory behaviour after acute or repeated antidepressant treatment in open-field and exploration-box tests. Baltic Journal of Laboratory Animal Science, 8, 145−157.
2.3.
1998
Matto, Vallo (1998). Pharmacological studies on anxiogenic and antiaggressive properties of antidepressants. Tartu: Tartu University Press.
5.1.
1998
Allikmets, L.; Matto, V.; Skrebuhhova, T. (1998). Anxiogenics have similarities with antidepressants in forced swimming (Porsolt') test. Naunyn-Schmiedebergs Archives of Pharmacology, 358 (4), R765−R765.
1.1.
1997
Matto, V.; Harro, J.; Allikmets, L. (1997). The effect of drugs acting on CCK receptors and rat free exploration in the exploration box. Journal of Physiology and Pharmacology, 48 (2), 239−251.
1.1.
1997
Matto, V.; Harro, J.; Allikmets, L. (1997). The effects of cholecystokinin A and B receptor antagonists on exploratory behaviour in the elevated zero-maze in rat. Neuropharmacology, 36 (3), 389−396.
1.1.
1997
Otter, MH.; Matto, V.; Sõukand, R.; Skrebuhhova, T.; Allikmets, L.; Harro, J. (1997). Characterization of rat exploratory behavior using the exploration box test. Methods and Findings in Experimental and Clinical Pharmacology, 19 (10), 683−691.
1.1.
1997
Harro, J.; Lofberg, C.; Pahkla, R.; Matto, V.; Rago, L.; Oreland, L.; Allikmets, L. (1997). Different molecular forms of cholecystokinin and CCKB receptor binding in the rat brain after chronic antidepressant treatment. Naunyn-Schmiedebergs Archives of Pharmacology, 355 (1), 57−63.
3.1.
1997
Otter, M.; Skrebuhhova, T.; Matto, V.; Harro, J. (1997). Measurement of exploratory behaviour in rat. Harmonization of laboratory animal husbandry: 6th Symposium of the Federation of European Laboratory Animal Science Associations; Basel, Switzerland; 19.-21.06.1996. Ed. O’Donoghue, P.N. London: Royal Soc Medicine Press Ltd, 21−23.
5.1.
1997
Allikmets, L.; Matto, V. (1997). Do the antidepressants have antiaggressive effect? Naunyn-Schmiedebergs Archives of Pharmacology, 356 (4), 86−86.
1.1.
1996
Matto, V.; Harro, J.; Allikmets, L. (1996). The effects of cholecystokinin A and B receptor antagonists, devazepide and L 365260, on citalopram-induced decrease of exploratory behaviour in rat. Journal of Physiology and Pharmacology, 47 (4), 661−669.
5.1.
1996
Allikmets, L.; Matto, V.; Harro, J. (1996). Anxiogenic component in the mechanism of action of antidepressants is essential for clinical effect. Naunyn-Schmiedebergs Archives of Pharmacology, 354 (4), 143−143.
5.1.
1996
Matto, V.; Allikmets, L.; Harro, J. (1996). The effect of CCKA and CCKB receptor antagonists on rat exploratory behaviour in the elevated zero-maze. Naunyn-Schmiedebergs Archives of Pharmacology, 354 (4), 146−146.
5.1.
1996
Allikmets, L.; Matto, V.; Harro, J. (1996). Do the antidepressants have anxiogenic action? Biological Psychiatry, 39 (7), 433−433.
18.04.2019
Detailne otsing
  • Leitud 4 kirjet
ProgrammLiikNumberNimiProjekti algusProjekti lõppVastutav täitjaAsutusFinantseerijapoolne rahastamine
ETFETF8414Meeleolustabilisaatorite toime rakusisesele signaaliülekandele volframiinipuudulikkusega hiire ajus.01.01.201031.12.2013Anton TerasmaaTartu Ülikool, Arstiteaduskond85 896,31 EUR
SFSF0182137s02Ravimpreparaatide keemilised, füsikokeemilised ja biofarmatseutilised uuringud - kvaliteedi hindamine ja parandamine.01.01.200231.12.2006Peep VeskiTartu Ülikool, Arstiteaduskond127 056,34 EUR
MUUMARFA11139Ravimpreparaatide tuleviku testimismeetodid01.10.201130.09.2014Jyrki Tapio HeinämäkiTartu Ülikool; Tartu Ülikool, Arstiteaduskond26 657,00 EUR
SFSF0180042s09Tahkete raviainete füsikokeemilised omadused ja nende modifitseerimise võimalused01.01.200931.12.2014Karin KogermannTartu Ülikool, Arstiteaduskond305 007,90 EUR