Yuri Kolesnikov

https://www.etis.ee/CV/Yuri_Kolesnikov/est
12.05.1958
37253663264
yuri.kolesnikov@itk.ee

Teenistuskäik

Töökohad ja ametid
01.07.2012–...   
AS Ida-Tallinna Keskhaigla, teadusosakonna spetsialist (0,65)
01.07.2012–...   
AS Ida-Tallinna Keskhaigla, palliatiivravi arst (0,25)
01.07.2012–...   
AS Ida-Tallinna Keskhaigla, anestesioloog (0,10)
2008–30.06.2012   
AS Ida-Tallinna Keskhaigla, Juhtivteadur (1,00)
01.05.2006–31.12.2008   
Tartu Ülikool, Loodus- ja tehnoloogiateaduskond, Tartu Ülikooli Tehnoloogiainstituut, erakorraline vanemteadur (1,00)
01.01.2001–31.12.2006   
Associate Professor in Neuropharmacology and Attending, Department of Anesthesiology, Memorial Sloan Kettering Cancer Center,New York, USA
01.01.1997–31.12.2001   
Assistant Professor in Neuropharmacology and Assistant Attending, Department of Anesthesiology, MSKCC, NY, USA
01.01.1994–31.12.1997   
Clinical Fellow, Pain Service, Dep Anesthesiology, Memorial Sloan Kettering Cancer Center, New York, USA
01.01.1992–31.12.1994   
Postdoc Fellow, Department of Neurology, Memorial Sloan Kettering Cancer Center, New York, USA
 
 
Haridustee
1994–1997   
Clinical Fellowship, Department of Anesthesiology, Pain Service, Sloan Kettering Cancer Center, New York, USA
1992–1994   
Post-doctoral fellowship in basic opioid pharmacology, Sloan Kettering Cancer Center, New York, USA
1983–1986   
Medical Faculty, PhD program, Tartu University, Tartu, Estonia
1975–1981   
Medical Faculty, Tartu University, Tartu, Estonia
 
 
Teadusorganisatsiooniline ja -administratiivne tegevus
1999−2006   
Group leader, Laboratory of the Molecular Neuropharmacology, Sloan Kettering Institute, New York, USA
1988−1992   
Director of Research, Department of Anesthesiology, Tartu University, Tartu, Estonia

Kvalifikatsioon

Teaduskraadid
Yuri Kolesnikov, doktorikraad, 1988, (juh) Jüri samarütel, Prolonged epidural analgesia by morphine and lidocaine during and after oncoabdominal surgery, Tartu Ülikool.
 
 
Teaduspreemiad ja tunnustused
2003, Yuri Kolesnikov, Abbot lab Industrial grant
2001, Yuri Kolesnikov, EpiCept Pharmaceutical Industrial grant
2000, Yuri Kolesnikov, The best poster at the Third Congress of the European Federation of IASP, France
1998, Yuri Kolesnikov, NIH RO1 grant
1994, Yuri Kolesnikov, The Norman and Rosita Winston Foundation,Fellowship Grant in Biomedicine
 
 
Teadustöö põhisuunad
VALDKOND: 1. Bio- ja keskkonnateadused; 1.3. Geneetika
VALDKOND: 3. Terviseuuringud; 3.7. Kliiniline meditsiin

Juhendamisel väitekirjad

Publikatsioonid

Klass
Aasta
Publikatsioon
 
1.1.
2014
Lelic, D.; Olesen, AE.; Gregersen, H.; Dahan, A.; Kolesnikov, Y.; Drewes, AM. (2014). Morphine modifies the cingulate-operculum network underlying painful rectal evoked potentials. Neuropharmacology, 77, 422−427.10.1016/j.neuropharm.2013.10.020.
1.1.
2014
Olesen, SS.; Juel, J.; Graversen, C.; Kolesnikov, Y.; Wilder-Smith, OHG.; Drewes, AM. (2014). Pharmacological pain management in chronic pancreatitis. World Journal of Gastroenterology, 19 (42), 7292−7301.10.3748/wjg.v19.i42.7292.
1.1.
2011
El Maarouf, A.; Kolesnikov, Y.; Pasternak, G.; Rutishauser, U. (2011). Removal of polysialylated neural cell adhesion molecule increases morphine analgesia and interferes with tolerance in mice. Brain Research, Aug 2 (1404), 55−62.
1.1.
2011
Kolesnikov, Yuri; Gabovits, Boris; Levin, Ariel; Voiko, Edward; Veske, Andres (2011). Combined Catechol-O-Methyltransferase and {micro}-Opioid Receptor Gene Polymorphisms Affect Morphine Postoperative Analgesia and Central Side Effects. Anesthesia and Analgesia, 112 (2), 448−453.
1.1.
2010
Kolesnikov Y, Gabovits B , Levin A, Voiko E and Veske (2010). Combined Catechol-O-Methyltransferase and µ-Opioid Receptor Gene Polymorphisms Affect Morphine Postoperative Analgesia and Central Side Effects. Anesthesia and Analgesia, 76−80.
1.1.
2010
Kolesnikov YA, Oksman G, Pasternak GW. (2010). Topical methadone and meperidine analgesic synergy in the mouse. European Journal of Pharmacology, 25 (638), 61−64.
1.1.
2009
Kolesnikov, Y.; Chereshnev, I.; Criesta, M.; Pan, Y.X.; Pasternak, G.W. (2009). Opposing actions of neuronal nitric oxide synthase isoforms in formalin-induced pain in mice. Brain Research, 15 (1289), 14−21.
1.1.
2008
Kolesnikov, Y., Sõritsa, D. (2008). Analgesic synergy between topical opioids and topical non-steroidal anti-inflammatory drugs in the mouse model of thermal pain. European Journal of Pharmacology, 579, 126−133.10.1016/j.ejphar.2007.10.014.
1.2.
2007
Kolesnikov, Y.; Abderrahman, A.E.-M; Rutinhauser, U.; Pasternak, G. (2007). Reorganization of dorsal root ganglion neurons following chronic sciatic nerve constriction injury: Correlation with morphine and lidocaine analgesia. European Journal of Pharmacology, 568, 124−133.
1.2.
2006
Zhang, Y.; Pan, YX.; Yuri Kolesnikov, Y.; Pasternak, GW. (2006). Immunohistochemical labeling of the mu opioid receptor carboxy terminal splice variant mMOR-1B4 in the mouse central nervous system. Brain Research, 1099 (1), 33−43.
1.1.
2005
Zelcer, S.; Kolesnikov, Y.; Kovalyshyn, I.; Pasternak, DA.; Pasternak, GW. (2005). Selective potentiation of opioid analgesia by nonsteroidal anti-inflammatory drugs. Brain Research, 1040, 151−156.
1.1.
2005
El Maarouf, A.; Kolesnikov, Y.; Pasternak, G.; Rutishauser, U. (2005). Polysialic acid-induced plasticity reduces neuropathic insult to the central nervous system. Proceedings of the National Academy of Sciences of the United States of America, 102 (32), 11516−11520.
1.1.
2004
Kolesnikov, Y.; Cristea, M.; Oksman, G.; Torosjan, A.; Wilson, R. (2004). Evaluation of the tail formalin test in mice as a new model to assess local analgesic effects. Brain Research, 1029 (2), 217−223.
1.1.
2003
Rousselle, C.; Clair, P.; Smirnova, M.; Kolesnikov, Y.; Pasternak, G.W.; Gac-Breton, S.; Rees, A.R.; Scherrmann, J.M., Temsamani, J. (2003). Improved brain uptake and pharmacological activity of dalargin using a peptide-vector-mediated strategy. Journal of Pharmacology and Experimental Therapeutics, 306, 1, 371−376.
1.1.
2003
Kolesnikov, YA.; Cristea, M.; Pasternak, GW. (2003). Analgesic synergy between topical morphine and butamben in mice. Anesthesia and Analgesia, 97 (4), 1103−1107.
1.1.
2003
Kolesnikov, YA.; Wilson, RS.; Pasternak, GW. (2003). The synergistic analgesic interactions between hydrocodone and ibuprofen. Anesthesia and Analgesia, 97 (6), 1721−1723.
1.1.
2000
Kolesnikov, YA.; Chereshnev, I.; Pasternak, GW. (2000). Analgesic synergy between topical lidocaine and topical opioids. Journal of Pharmacology and Experimental Therapeutics, 295 (2), 546−551.
1.1.
1999
Kolesnikov, Y.; Pasternak, GW. (1999). Topical opioids in mice: Analgesia and reversal of tolerance by a topical N-methyl-D-aspartate antagonist. Journal of Pharmacology and Experimental Therapeutics, 290 (1), 247−252.
1.2.
1999
Kolesnikov, Y.A.; Pasternak, G.W. (1999). Peripheral orphanin FQ/nociceptin analgesia in the mouse. Life Sciences, 64, 22, 2021−2028.
1.2.
1999
Kolesnikov, Y.A.; Pasternak, G.W. (1999). Peripheral blockade of topical morphine tolerance by ketamine. European Journal of Pharmacology, 374, 2, R1−R2.
1.1.
1998
Kolesnikov, Y.; Jain, S.; Wilson, R.; Pasternak, G.W. (1998). Lack of morphine and enkephalin tolerance in 129/SvEv mice: evidence for a NMDA receptor defect. Journal of Pharmacology and Experimental Therapeutics, 284 (2), 455−459.
1.1.
1997
Kolesnikov, Y.; Jain, S.; Wilson, R.; Pasternak, G.W. (1997). Blockade of morphine-induced hindlimb myoclonic seizures in mice by ketamine. Pharmacology Biochemistry & Behavior, 56 (3), 423−425.
1.1.
1997
Kolesnikov, Y.A.; Pan, Y.X.; Babey, A.M.; Jain, S.; Wilson, R; Pasternak, G.W. (1997). Functionally differentiating two neuronal nitric oxide synthase isoforms through antisense mapping: evidence for opposing NO actions on morphine analgesia and tolerance. Proceedings of the National Academy of Sciences of the United States of America, 94, 15, 8220−8225.
1.1.
1996
Kolesnikov, YA.; Jain, S.; Wilson, R.; Pasternak, GW. (1996). Peripheral morphine analgesia: Synergy with central sites and a target of morphine tolerance. Journal of Pharmacology and Experimental Therapeutics, 279 (2), 502−506.
1.2.
1996
Kolesnikov, Y.; Jain, S.; Pasternak, G.W. (1996). Modulation of opioid analgesia by agmatine. European Journal of Pharmacology, 296, 1, 17−22.
1.2.
1995
Pasternak, G.W.; Kolesnikov, Y.A.; Babey, A.M. (1995). Perspectives on the N-methyl-D-aspartate/nitric oxide cascade and opioid tolerance. Neuropsychopharmacology, 13, 4, 309−313.
1.1.
1994
Elliott, K., Minami. N., Kolesnikov, Y.A., Pasternak, G.W., Inturrisi, C.E. (1994). The NMDA receptor antagonists, LY274614 and MK-801, and the nitric oxide synthase inhibitor, NG-nitro-L-arginine, attenuate analgesic tolerance to the mu-opioid morphine but not to kappa opioids. Pain, 56 (1), 69−75.
1.2.
1994
Kolesnikov, Y.A.; Maccechini, M.L.; Pasternak, G.W. (1994). 1-Aminocyclopropane carboxylic acid (ACPC) prevents mu and delta opioid tolerance. Life Sciences, 55, 18, 1393−1398.
1.2.
1994
Babey, A.M.; Kolesnikov, Y.; Cheng, J.; Inturrisi, C.E.; Trifilletti, R.R.; Pasternak, G.W. (1994). Nitric oxide and opioid tolerance. Neuropharmacology, 33, 11, 1463−1470.
1.1.
1993
Kolesnikov, Y.A., Pick, C.G., Ciszewska, G., Pasternak, G.W. (1993). Blockade of tolerance to morphine but not to kappa opioids by a nitric oxide synthase inhibitor. Proceedings of the National Academy of Sciences of the United States of America, 90 (11), 5162−5166.
1.2.
1992
Kolesnikov, Y.A.; Pick, C.G.; Pasternak, G.W. (1992). NG-nitro-L-arginine prevents morphine tolerance. European Journal of Pharmacology, 221, 399−400.

Tööstusomand

5.04.2018

Yuri Kolesnikov

https://www.etis.ee/CV/Yuri_Kolesnikov/eng
12.05.1958
37253663264
yuri.kolesnikov@itk.ee

Career

Institution(s) and position(s)
01.07.2012–...   
East Tallinn Central Hospital, Other staff (0,65)
01.07.2012–...   
East Tallinn Central Hospital, Other staff (0,25)
01.07.2012–...   
East Tallinn Central Hospital, Other staff (0,10)
2008–30.06.2012   
East Tallinn Central Hospital, Research Professor (1,00)
01.05.2006–31.12.2008   
University of Tartu, Faculty of Science and Technology (old), Institute of Technology, University of Tartu, Senior Research Fellow extraordinarius (1,00)

Qualifications

Academic degrees
Yuri Kolesnikov, Doctor's Degree, 1988, (sup) Jüri samarütel, Prolonged epidural analgesia by morphine and lidocaine during and after oncoabdominal surgery, University of Tartu.
 
 
Honours & awards
2003, Yuri Kolesnikov, Abbot lab Industrial grant
2001, Yuri Kolesnikov, EpiCept Pharmaceutical Industrial grant
2000, Yuri Kolesnikov, The best poster at the Third Congress of the European Federation of IASP, France
1998, Yuri Kolesnikov, NIH RO1 grant
1994, Yuri Kolesnikov, The Norman and Rosita Winston Foundation, Fellowship Grant in Biomedicine
 
 
Field of research
FIELD OF RESEARCH: 1. Biosciences and Environment; 1.3. Genetics
FIELD OF RESEARCH: 3. Health; 3.7. Clinical Medicine
 
 

Dissertations under supervision

Publications

Category
Year
Publication
 
1.1.
2014
Lelic, D.; Olesen, AE.; Gregersen, H.; Dahan, A.; Kolesnikov, Y.; Drewes, AM. (2014). Morphine modifies the cingulate-operculum network underlying painful rectal evoked potentials. Neuropharmacology, 77, 422−427.10.1016/j.neuropharm.2013.10.020.
1.1.
2014
Olesen, SS.; Juel, J.; Graversen, C.; Kolesnikov, Y.; Wilder-Smith, OHG.; Drewes, AM. (2014). Pharmacological pain management in chronic pancreatitis. World Journal of Gastroenterology, 19 (42), 7292−7301.10.3748/wjg.v19.i42.7292.
1.1.
2011
El Maarouf, A.; Kolesnikov, Y.; Pasternak, G.; Rutishauser, U. (2011). Removal of polysialylated neural cell adhesion molecule increases morphine analgesia and interferes with tolerance in mice. Brain Research, Aug 2 (1404), 55−62.
1.1.
2011
Kolesnikov, Yuri; Gabovits, Boris; Levin, Ariel; Voiko, Edward; Veske, Andres (2011). Combined Catechol-O-Methyltransferase and {micro}-Opioid Receptor Gene Polymorphisms Affect Morphine Postoperative Analgesia and Central Side Effects. Anesthesia and Analgesia, 112 (2), 448−453.
1.1.
2010
Kolesnikov Y, Gabovits B , Levin A, Voiko E and Veske (2010). Combined Catechol-O-Methyltransferase and µ-Opioid Receptor Gene Polymorphisms Affect Morphine Postoperative Analgesia and Central Side Effects. Anesthesia and Analgesia, 76−80.
1.1.
2010
Kolesnikov YA, Oksman G, Pasternak GW. (2010). Topical methadone and meperidine analgesic synergy in the mouse. European Journal of Pharmacology, 25 (638), 61−64.
1.1.
2009
Kolesnikov, Y.; Chereshnev, I.; Criesta, M.; Pan, Y.X.; Pasternak, G.W. (2009). Opposing actions of neuronal nitric oxide synthase isoforms in formalin-induced pain in mice. Brain Research, 15 (1289), 14−21.
1.1.
2008
Kolesnikov, Y., Sõritsa, D. (2008). Analgesic synergy between topical opioids and topical non-steroidal anti-inflammatory drugs in the mouse model of thermal pain. European Journal of Pharmacology, 579, 126−133.10.1016/j.ejphar.2007.10.014.
1.2.
2007
Kolesnikov, Y.; Abderrahman, A.E.-M; Rutinhauser, U.; Pasternak, G. (2007). Reorganization of dorsal root ganglion neurons following chronic sciatic nerve constriction injury: Correlation with morphine and lidocaine analgesia. European Journal of Pharmacology, 568, 124−133.
1.2.
2006
Zhang, Y.; Pan, YX.; Yuri Kolesnikov, Y.; Pasternak, GW. (2006). Immunohistochemical labeling of the mu opioid receptor carboxy terminal splice variant mMOR-1B4 in the mouse central nervous system. Brain Research, 1099 (1), 33−43.
1.1.
2005
Zelcer, S.; Kolesnikov, Y.; Kovalyshyn, I.; Pasternak, DA.; Pasternak, GW. (2005). Selective potentiation of opioid analgesia by nonsteroidal anti-inflammatory drugs. Brain Research, 1040, 151−156.
1.1.
2005
El Maarouf, A.; Kolesnikov, Y.; Pasternak, G.; Rutishauser, U. (2005). Polysialic acid-induced plasticity reduces neuropathic insult to the central nervous system. Proceedings of the National Academy of Sciences of the United States of America, 102 (32), 11516−11520.
1.1.
2004
Kolesnikov, Y.; Cristea, M.; Oksman, G.; Torosjan, A.; Wilson, R. (2004). Evaluation of the tail formalin test in mice as a new model to assess local analgesic effects. Brain Research, 1029 (2), 217−223.
1.1.
2003
Rousselle, C.; Clair, P.; Smirnova, M.; Kolesnikov, Y.; Pasternak, G.W.; Gac-Breton, S.; Rees, A.R.; Scherrmann, J.M., Temsamani, J. (2003). Improved brain uptake and pharmacological activity of dalargin using a peptide-vector-mediated strategy. Journal of Pharmacology and Experimental Therapeutics, 306, 1, 371−376.
1.1.
2003
Kolesnikov, YA.; Cristea, M.; Pasternak, GW. (2003). Analgesic synergy between topical morphine and butamben in mice. Anesthesia and Analgesia, 97 (4), 1103−1107.
1.1.
2003
Kolesnikov, YA.; Wilson, RS.; Pasternak, GW. (2003). The synergistic analgesic interactions between hydrocodone and ibuprofen. Anesthesia and Analgesia, 97 (6), 1721−1723.
1.1.
2000
Kolesnikov, YA.; Chereshnev, I.; Pasternak, GW. (2000). Analgesic synergy between topical lidocaine and topical opioids. Journal of Pharmacology and Experimental Therapeutics, 295 (2), 546−551.
1.1.
1999
Kolesnikov, Y.; Pasternak, GW. (1999). Topical opioids in mice: Analgesia and reversal of tolerance by a topical N-methyl-D-aspartate antagonist. Journal of Pharmacology and Experimental Therapeutics, 290 (1), 247−252.
1.2.
1999
Kolesnikov, Y.A.; Pasternak, G.W. (1999). Peripheral orphanin FQ/nociceptin analgesia in the mouse. Life Sciences, 64, 22, 2021−2028.
1.2.
1999
Kolesnikov, Y.A.; Pasternak, G.W. (1999). Peripheral blockade of topical morphine tolerance by ketamine. European Journal of Pharmacology, 374, 2, R1−R2.
1.1.
1998
Kolesnikov, Y.; Jain, S.; Wilson, R.; Pasternak, G.W. (1998). Lack of morphine and enkephalin tolerance in 129/SvEv mice: evidence for a NMDA receptor defect. Journal of Pharmacology and Experimental Therapeutics, 284 (2), 455−459.
1.1.
1997
Kolesnikov, Y.; Jain, S.; Wilson, R.; Pasternak, G.W. (1997). Blockade of morphine-induced hindlimb myoclonic seizures in mice by ketamine. Pharmacology Biochemistry & Behavior, 56 (3), 423−425.
1.1.
1997
Kolesnikov, Y.A.; Pan, Y.X.; Babey, A.M.; Jain, S.; Wilson, R; Pasternak, G.W. (1997). Functionally differentiating two neuronal nitric oxide synthase isoforms through antisense mapping: evidence for opposing NO actions on morphine analgesia and tolerance. Proceedings of the National Academy of Sciences of the United States of America, 94, 15, 8220−8225.
1.1.
1996
Kolesnikov, YA.; Jain, S.; Wilson, R.; Pasternak, GW. (1996). Peripheral morphine analgesia: Synergy with central sites and a target of morphine tolerance. Journal of Pharmacology and Experimental Therapeutics, 279 (2), 502−506.
1.2.
1996
Kolesnikov, Y.; Jain, S.; Pasternak, G.W. (1996). Modulation of opioid analgesia by agmatine. European Journal of Pharmacology, 296, 1, 17−22.
1.2.
1995
Pasternak, G.W.; Kolesnikov, Y.A.; Babey, A.M. (1995). Perspectives on the N-methyl-D-aspartate/nitric oxide cascade and opioid tolerance. Neuropsychopharmacology, 13, 4, 309−313.
1.1.
1994
Elliott, K., Minami. N., Kolesnikov, Y.A., Pasternak, G.W., Inturrisi, C.E. (1994). The NMDA receptor antagonists, LY274614 and MK-801, and the nitric oxide synthase inhibitor, NG-nitro-L-arginine, attenuate analgesic tolerance to the mu-opioid morphine but not to kappa opioids. Pain, 56 (1), 69−75.
1.2.
1994
Kolesnikov, Y.A.; Maccechini, M.L.; Pasternak, G.W. (1994). 1-Aminocyclopropane carboxylic acid (ACPC) prevents mu and delta opioid tolerance. Life Sciences, 55, 18, 1393−1398.
1.2.
1994
Babey, A.M.; Kolesnikov, Y.; Cheng, J.; Inturrisi, C.E.; Trifilletti, R.R.; Pasternak, G.W. (1994). Nitric oxide and opioid tolerance. Neuropharmacology, 33, 11, 1463−1470.
1.1.
1993
Kolesnikov, Y.A., Pick, C.G., Ciszewska, G., Pasternak, G.W. (1993). Blockade of tolerance to morphine but not to kappa opioids by a nitric oxide synthase inhibitor. Proceedings of the National Academy of Sciences of the United States of America, 90 (11), 5162−5166.
1.2.
1992
Kolesnikov, Y.A.; Pick, C.G.; Pasternak, G.W. (1992). NG-nitro-L-arginine prevents morphine tolerance. European Journal of Pharmacology, 221, 399−400.

Industrial property

5.04.2018
Detailne otsing
  • Leitud 2 kirjet
ProgrammLiikNumberNimiProjekti algusProjekti lõppVastutav täitjaAsutusFinantseerijapoolne rahastamine
SFSF0180027s08Koespetsiifilised transportvektorid01.01.200831.12.2013Ülo LangelTartu Ülikool, Loodus- ja tehnoloogiateaduskond, Tartu Ülikooli Tehnoloogiainstituut600 272,61 EUR
SFSF0180100s08Signaaliülekande rajad inimese tüvirakkudes, nende diferentseerunud järglastes ja kasvajarakkudes.01.01.200831.12.2013Toivo MaimetsTartu Ülikool, Bioloogia-geograafiateaduskond; Tartu Ülikool, Loodus- ja tehnoloogiateaduskond, Tartu Ülikooli Molekulaar- ja Rakubioloogia Instituut; Tartu Ülikool, Loodus- ja tehnoloogiateaduskond457 071,51 EUR