Natalia Pervjakova

https://www.etis.ee/CV/Natalia_Pervjakova/eng
27.11.1987
737 4045
natalia.pervjakova@ut.ee

Career

Institutions and positions
01.06.2016–...   
University of Tartu, Estonian Genome Center , Specialist (1,00)
01.10.2012–31.05.2016   
University of Tartu, Estonian Genome Center , Specialist (0,50)
01.09.2012–30.09.2012   
University of Tartu, Estonian Genome Center , Laboratory Assistant (0,50)
08.11.2011–31.08.2012   
University of Tartu, Estonian Genome Center , Laboratory Assistant (1,00)
01.07.2008–31.07.2008   
University of Tartu, Faculty of Science and Technology (old), Institute of Molecular and Cell Biology, University of Tartu, Laboratory Assistant (1,00)

Qualifications

Academic degrees
Natalia Pervjakova, Doctor's Degree, 2018, (sup) Reedik Mägi; Andres Metspalu, Genomic imprinting in complex traits, University of Tartu, Faculty of Science and Technology, Institute of Molecular and Cell Biology.
Natalia Pervjakova, Master's Degree, 2012, (sup) Andres Metspalu; Evelin Mihailov; Reedik Mägi, Ülegenoomne assotsiatsiooniuuring kubemesonga geneetiliste markerite leidmiseks Eesti populatsioonis (Genome-Wide Association Study for Inguinal Hernia in Estonian Population), University of Tartu, Faculty of Science and Technology (old), Institute of Molecular and Cell Biology, University of Tartu.
 
 
Fields of research
ETIS CLASSIFICATION: 1. Biosciences and Environment; 1.12. Biotechnology, Molecular Biology, Cell Biology, Biophysics and Economic and Technological Research relating to Bio- and Environmental Sciences; CERCS CLASSIFICATION: T490 Biotechnology
 
 

Projects in progress

Completed projects

Publications

Category
Year
Publication
 
1.1.
2017
Wahl, Simone; Drong, Alexander; Lehne, Benjamin; Loh, Marie; Scott, William R; Kunze, Sonja; Tsai, Pei-Chien; Ried, Janina S; Zhang, Weihua; Yang, Youwen; Tan, Sili; Fiorito, Giovanni; Franke, Lude; Guarrera, Simonetta; Kasela, Silva; Kriebel, Jennifer; Richmond, Rebecca C; Adamo, Marco; Afzal, Uzma; Ala-Korpela, Mika ... Chambers, John C (2017). Epigenome-wide association study of body mass index, and the adverse outcomes of adiposity. Nature, 541 (7635), 81−86.10.1038/nature20784.
1.1.
2017
Justice, Anne E.; Winkler, Thomas W.; Feitosa, Mary F.; Graff, Misa; Fisher, Virginia A.; Young, Kristin; Barata, Llilda; Deng, Xuan; Czajkowski, Jacek; Hadley, David; Ngwa, Julius S.; Ahluwalia, Tarunveer S.; Chu, Audrey Y.; Heard-Costa, Nancy L.; Lim, Elise; Perez, Jeremiah; Eicher, John D.; Kutalik, Zoltan; Xue, Luting; Mahajan, Anubha ... Cupples, L. Adrienne (2017). Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits. Nature Communications, 8 (14977), ARTN 14977.10.1038/ncomms14977.
1.1.
2017
Day, Felix R.; Thompson, Deborah J.; Helgason, Hannes; Chasman, Daniel I.; Finucane, Hilary; Sulem, Patrick; Ruth, Katherine S.; Whalen, Sean; Sarkar, Abhishek K.; Albrecht, Eva; Altmaier, Elisabeth; Amini, Marzyeh; Barbieri, Caterina M.; Boutin, Thibaud; Campbell, Archie; Demerath, Ellen; Giri, Ayush; He, Chunyan; Hottenga, Jouke J.; Karlsson, Robert ... Perry, John R. B. (2017). Genomic analyses identify hundreds of variants associated with age at menarche and support a role for puberty timing in cancer risk. Nature Genetics, 49 (6), 834−845.10.1038/ng.3841.
1.1.
2017
Scott, Robert A.; Scott, Laura J.; Maegi, Reedik; Marullo, Letizia; Gaulton, Kyle J.; Kaakinen, Marika; Pervjakova, Natalia; Pers, Tune H.; Johnson, Andrew D.; Eicher, John D.; Jackson, Anne U.; Ferreira, Teresa; Lee, Yeji; Ma, Clement; Steinthorsdottir, Valgerdur; Thorleifsson, Gudmar; Qi, Lu; Van Zuydam, Natalie R.; Mahajan, Anubha; Chen, Han ... Prokopenko, Inga (2017). An Expanded Genome-Wide Association Study of Type 2 Diabetes in Europeans. Diabetes, 66 (11), 2888−2902.10.2337/db16-1253.
1.1.
2016
Pervjakova, Natalia; Kasela, Silva; Morris, Andrew P; Kals, Mart; Metspalu, Andres; Lindgren, Cecilia M; Salumets, Andres; Mägi, Reedik (2016). Imprinted genes and imprinting control regions show predominant intermediate methylation in adult somatic tissues. Epigenomics, 8 (6), 789−799.10.2217/epi.16.8.
1.1.
2016
Okbay, Aysu; Beauchamp, Jonathan P; Fontana, Mark Alan; Lee, James J; Pers, Tune H; Rietveld, Cornelius A; Turley, Patrick; Chen, Guo-Bo; Emilsson, Valur; Meddens, S Fleur W; Oskarsson, Sven; Pickrell, Joseph K; Thom, Kevin; Timshel, Pascal; de Vlaming, Ronald; Abdellaoui, Abdel; Ahluwalia, Tarunveer S; Bacelis, Jonas; Baumbach, Clemens; Bjornsdottir, Gyda ... Benjamin, Daniel J (2016). Genome-wide association study identifies 74 loci associated with educational attainment. Nature, 533 (7604), 539−542.10.1038/nature17671.
1.1.
2015
Nikpay, M; Goel, A; Won, HH; Hall, LM; Willenborg, C; Kanoni, S; Saleheen, D; Kyriakou, T; Nelson, CP; Hopewell, JC; Webb, TR; Zeng, L; Dehghan, A; Alver, M; Armasu, SM; Auro, K; Bjonnes, A; Chasman, DI; Chen, S; Ford, I ... Farrall, M. (2015). A comprehensive 1000 Genomes–based genome-wide association meta-analysis of coronary artery disease. Nature Genetics, 47 (10), 1121−1130.10.1038/ng.3396.
1.1.
2015
Surakka, I; Horikoshi, M; Mägi, R; Sarin, AP; Mahajan, A; Lagou, V; Marullo, L; Ferreira, T; Miraglio, B; Timonen, S; Kettunen, J; Pirinen, M; Karjalainen, J; Thorleifsson, G; Hägg, S; Hottenga, JJ; Isaacs, A; Ladenvall, C; Beekman, M; Esko, T ... ENGAGE, Consortium. (2015). The impact of low-frequency and rare variants on lipid levels. Nature Genetics, 47 (6), 589−597.10.1038/ng.3300.
1.1.
2015
Horikoshi, M; Mӓgi, R; van, de, Bunt, M; Surakka, I; Sarin, AP; Mahajan, A; Marullo, L; Thorleifsson, G; Hӓgg, S; Hottenga, JJ; Ladenvall, C; Ried, JS; Winkler, TW; Willems, SM; Pervjakova, N; Esko, T; Beekman, M; Nelson, CP; Willenborg, C; Wiltshire, S ... ENGAGE, Consortium. (2015). Discovery and Fine-Mapping of Glycaemic and Obesity-Related Trait Loci Using High-Density Imputation. Plos Genetics, 11 (7), e1005230.10.1371/journal.pgen.1005230.
1.1.
2015
Winkler, Thomas W.; Justice, Anne E.; Graff, Mariaelisa; Barata, Llilda; Feitosa, Mary F.; Chu, Su; Czajkowski, Jacek; Esko, Tonu; Fall, Tove; Kilpelainen, Tuomas O.; Lu, Yingchang; Magi, Reedik; Mihailov, Evelin; Pers, Tune H.; Rueeger, Sina; Teumer, Alexander; Ehret, Georg B.; Ferreira, Teresa; Heard-Costa, Nancy L.; Karjalainen, Juha ... Loos, Ruth J. F. (2015). The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study. Plos Genetics, 11 (10), ARTN e1005378.10.1371/journal.pgen.1005378.
1.1.
2015
Day, Felix R; Ruth, Katherine S; Thompson, Deborah J; Lunetta, Kathryn L; Pervjakova, Natalia; Chasman, Daniel I; Stolk, Lisette; Finucane, Hilary K; Sulem, Patrick; Bulik-Sullivan, Brendan; Esko, Tõnu; Johnson, Andrew D; Elks, Cathy E; Franceschini, Nora; He, Chunyan; Altmaier, Elisabeth; Brody, Jennifer A; Franke, Lude L; Huffman, Jennifer E; Keller, Margaux F ... Murray, Anna (2015). Large-scale genomic analyses link reproductive aging to hypothalamic signaling, breast cancer susceptibility and BRCA1-mediated DNA repair. Nature Genetics, 47 (11), 1294−303.10.1038/ng.3412.
1.1.
2014
Perry, J.R.B.; Day, F.; Elks, C.E.; Sulem, P.; Thompson, D.J.; Ferreira, T.; He, C.; Chasman, D.I.; Esko, T.; Thorleifsson, G.; Albrecht, E.; Ang, W.Q.; Corre, T.; Cousminer, D.L.; Feenstra, B.; Franceschini, N.; Ganna, A.; Johnson, A.D.; Kjellqvist, S.; Lunetta, K.L. ... Ong, K.K. (2014). Parent-of-origin-specific allelic associations among 106 genomic loci for age at menarche. Nature, 514 (7520), 92.10.1038/nature13545.
1.1.
2014
Hoggart, CJ; Venturini, G; Mangino, M; Gomez, F; Ascari, G; Zhao, JH; Teumer, A; Winkler, TW; Tsernikova, N; Luan, J; Mihailov, E; Ehret, GB; Zhang, W; Lamparter, D; Esko, T; Mace, A; Rueger, S; Bochud, P-Y; Barcella, M; Dauvilliers, Y ... Kutalik, Z. (2014). Novel Approach Identifies SNPs in SLC2A10 and KCNK9 with Evidence for Parent-of-Origin Effect on Body Mass Index. Plos Genetics, 10 (7), e1004508.10.1371/journal.pgen.1004508.
1.1.
2013
Tammiste, Anu; Jiang, Tao; Fischer, Krista; Mägi, Reedik; Krjutškov, Kaarel; Pettai, Kristi; Esko, Tõnu; Li, Yingrui; Tansey, Katherine E; Carroll, Liam S; Uher, Rudolf; McGuffin, Peter; Võsa, Urmo; Tšernikova, Natalia; Saria, Alois; Ng, Pauline C; Eller, Triin; Vasar, Veiko; Nutt, David J; Maron, Eduard ... Metspalu, Andres (2013). Whole-exome sequencing identifies a polymorphism in the BMP5 gene associated with SSRI treatment response in major depression. Journal of Psychopharmacology, 27 (10), 915−920.10.1177/0269881113499829.
15.05.2019

Natalia Pervjakova

https://www.etis.ee/CV/Natalia_Pervjakova/est
27.11.1987
737 4045
natalia.pervjakova@ut.ee

Teenistuskäik

Töökohad ja ametid
01.06.2016–...   
Tartu Ülikool, Tartu Ülikooli Eesti Geenivaramu, spetsialist (1,00)
01.10.2012–31.05.2016   
Tartu Ülikool, Tartu Ülikooli Eesti Geenivaramu, spetsialist (0,50)
01.09.2012–30.09.2012   
Tartu Ülikool, Tartu Ülikooli Eesti Geenivaramu, laborant (0,50)
08.11.2011–31.08.2012   
Tartu Ülikool, Tartu Ülikooli Eesti Geenivaramu, laborant (1,00)
01.07.2008–31.07.2008   
Tartu Ülikool, Loodus- ja tehnoloogiateaduskond, Tartu Ülikooli Molekulaar- ja Rakubioloogia Instituut, laborant (1,00)

Kvalifikatsioon

Teaduskraadid
Natalia Pervjakova, Doctor's Degree, 2018, (sup) Reedik Mägi; Andres Metspalu, Genomic imprinting in complex traits, University of Tartu, Faculty of Science and Technology, Institute of Molecular and Cell Biology.
Natalia Pervjakova, Master's Degree, 2012, (sup) Andres Metspalu; Evelin Mihailov; Reedik Mägi, Ülegenoomne assotsiatsiooniuuring kubemesonga geneetiliste markerite leidmiseks Eesti populatsioonis (Genome-Wide Association Study for Inguinal Hernia in Estonian Population), University of Tartu, Faculty of Science and Technology (old), Institute of Molecular and Cell Biology, University of Tartu.
 
 
Teadustöö põhisuunad
ETIS KLASSIFIKAATOR: 1. Bio- ja keskkonnateadused; 1.12. Bio- ja keskkonnateadustega seotud uuringud, näiteks biotehnoloogia, molekulaarbioloogia, rakubioloogia, biofüüsika, majandus- ja tehnoloogiauuringud; CERCS KLASSIFIKAATOR: T490 Biotehnoloogia

Jooksvad projektid

Lõppenud projektid

Publikatsioonid

Klass
Aasta
Publikatsioon
 
1.1.
2017
Wahl, Simone; Drong, Alexander; Lehne, Benjamin; Loh, Marie; Scott, William R; Kunze, Sonja; Tsai, Pei-Chien; Ried, Janina S; Zhang, Weihua; Yang, Youwen; Tan, Sili; Fiorito, Giovanni; Franke, Lude; Guarrera, Simonetta; Kasela, Silva; Kriebel, Jennifer; Richmond, Rebecca C; Adamo, Marco; Afzal, Uzma; Ala-Korpela, Mika ... Chambers, John C (2017). Epigenome-wide association study of body mass index, and the adverse outcomes of adiposity. Nature, 541 (7635), 81−86.10.1038/nature20784.
1.1.
2017
Justice, Anne E.; Winkler, Thomas W.; Feitosa, Mary F.; Graff, Misa; Fisher, Virginia A.; Young, Kristin; Barata, Llilda; Deng, Xuan; Czajkowski, Jacek; Hadley, David; Ngwa, Julius S.; Ahluwalia, Tarunveer S.; Chu, Audrey Y.; Heard-Costa, Nancy L.; Lim, Elise; Perez, Jeremiah; Eicher, John D.; Kutalik, Zoltan; Xue, Luting; Mahajan, Anubha ... Cupples, L. Adrienne (2017). Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits. Nature Communications, 8 (14977), ARTN 14977.10.1038/ncomms14977.
1.1.
2017
Day, Felix R.; Thompson, Deborah J.; Helgason, Hannes; Chasman, Daniel I.; Finucane, Hilary; Sulem, Patrick; Ruth, Katherine S.; Whalen, Sean; Sarkar, Abhishek K.; Albrecht, Eva; Altmaier, Elisabeth; Amini, Marzyeh; Barbieri, Caterina M.; Boutin, Thibaud; Campbell, Archie; Demerath, Ellen; Giri, Ayush; He, Chunyan; Hottenga, Jouke J.; Karlsson, Robert ... Perry, John R. B. (2017). Genomic analyses identify hundreds of variants associated with age at menarche and support a role for puberty timing in cancer risk. Nature Genetics, 49 (6), 834−845.10.1038/ng.3841.
1.1.
2017
Scott, Robert A.; Scott, Laura J.; Maegi, Reedik; Marullo, Letizia; Gaulton, Kyle J.; Kaakinen, Marika; Pervjakova, Natalia; Pers, Tune H.; Johnson, Andrew D.; Eicher, John D.; Jackson, Anne U.; Ferreira, Teresa; Lee, Yeji; Ma, Clement; Steinthorsdottir, Valgerdur; Thorleifsson, Gudmar; Qi, Lu; Van Zuydam, Natalie R.; Mahajan, Anubha; Chen, Han ... Prokopenko, Inga (2017). An Expanded Genome-Wide Association Study of Type 2 Diabetes in Europeans. Diabetes, 66 (11), 2888−2902.10.2337/db16-1253.
1.1.
2016
Pervjakova, Natalia; Kasela, Silva; Morris, Andrew P; Kals, Mart; Metspalu, Andres; Lindgren, Cecilia M; Salumets, Andres; Mägi, Reedik (2016). Imprinted genes and imprinting control regions show predominant intermediate methylation in adult somatic tissues. Epigenomics, 8 (6), 789−799.10.2217/epi.16.8.
1.1.
2016
Okbay, Aysu; Beauchamp, Jonathan P; Fontana, Mark Alan; Lee, James J; Pers, Tune H; Rietveld, Cornelius A; Turley, Patrick; Chen, Guo-Bo; Emilsson, Valur; Meddens, S Fleur W; Oskarsson, Sven; Pickrell, Joseph K; Thom, Kevin; Timshel, Pascal; de Vlaming, Ronald; Abdellaoui, Abdel; Ahluwalia, Tarunveer S; Bacelis, Jonas; Baumbach, Clemens; Bjornsdottir, Gyda ... Benjamin, Daniel J (2016). Genome-wide association study identifies 74 loci associated with educational attainment. Nature, 533 (7604), 539−542.10.1038/nature17671.
1.1.
2015
Nikpay, M; Goel, A; Won, HH; Hall, LM; Willenborg, C; Kanoni, S; Saleheen, D; Kyriakou, T; Nelson, CP; Hopewell, JC; Webb, TR; Zeng, L; Dehghan, A; Alver, M; Armasu, SM; Auro, K; Bjonnes, A; Chasman, DI; Chen, S; Ford, I ... Farrall, M. (2015). A comprehensive 1000 Genomes–based genome-wide association meta-analysis of coronary artery disease. Nature Genetics, 47 (10), 1121−1130.10.1038/ng.3396.
1.1.
2015
Surakka, I; Horikoshi, M; Mägi, R; Sarin, AP; Mahajan, A; Lagou, V; Marullo, L; Ferreira, T; Miraglio, B; Timonen, S; Kettunen, J; Pirinen, M; Karjalainen, J; Thorleifsson, G; Hägg, S; Hottenga, JJ; Isaacs, A; Ladenvall, C; Beekman, M; Esko, T ... ENGAGE, Consortium. (2015). The impact of low-frequency and rare variants on lipid levels. Nature Genetics, 47 (6), 589−597.10.1038/ng.3300.
1.1.
2015
Horikoshi, M; Mӓgi, R; van, de, Bunt, M; Surakka, I; Sarin, AP; Mahajan, A; Marullo, L; Thorleifsson, G; Hӓgg, S; Hottenga, JJ; Ladenvall, C; Ried, JS; Winkler, TW; Willems, SM; Pervjakova, N; Esko, T; Beekman, M; Nelson, CP; Willenborg, C; Wiltshire, S ... ENGAGE, Consortium. (2015). Discovery and Fine-Mapping of Glycaemic and Obesity-Related Trait Loci Using High-Density Imputation. Plos Genetics, 11 (7), e1005230.10.1371/journal.pgen.1005230.
1.1.
2015
Winkler, Thomas W.; Justice, Anne E.; Graff, Mariaelisa; Barata, Llilda; Feitosa, Mary F.; Chu, Su; Czajkowski, Jacek; Esko, Tonu; Fall, Tove; Kilpelainen, Tuomas O.; Lu, Yingchang; Magi, Reedik; Mihailov, Evelin; Pers, Tune H.; Rueeger, Sina; Teumer, Alexander; Ehret, Georg B.; Ferreira, Teresa; Heard-Costa, Nancy L.; Karjalainen, Juha ... Loos, Ruth J. F. (2015). The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study. Plos Genetics, 11 (10), ARTN e1005378.10.1371/journal.pgen.1005378.
1.1.
2015
Day, Felix R; Ruth, Katherine S; Thompson, Deborah J; Lunetta, Kathryn L; Pervjakova, Natalia; Chasman, Daniel I; Stolk, Lisette; Finucane, Hilary K; Sulem, Patrick; Bulik-Sullivan, Brendan; Esko, Tõnu; Johnson, Andrew D; Elks, Cathy E; Franceschini, Nora; He, Chunyan; Altmaier, Elisabeth; Brody, Jennifer A; Franke, Lude L; Huffman, Jennifer E; Keller, Margaux F ... Murray, Anna (2015). Large-scale genomic analyses link reproductive aging to hypothalamic signaling, breast cancer susceptibility and BRCA1-mediated DNA repair. Nature Genetics, 47 (11), 1294−303.10.1038/ng.3412.
1.1.
2014
Perry, J.R.B.; Day, F.; Elks, C.E.; Sulem, P.; Thompson, D.J.; Ferreira, T.; He, C.; Chasman, D.I.; Esko, T.; Thorleifsson, G.; Albrecht, E.; Ang, W.Q.; Corre, T.; Cousminer, D.L.; Feenstra, B.; Franceschini, N.; Ganna, A.; Johnson, A.D.; Kjellqvist, S.; Lunetta, K.L. ... Ong, K.K. (2014). Parent-of-origin-specific allelic associations among 106 genomic loci for age at menarche. Nature, 514 (7520), 92.10.1038/nature13545.
1.1.
2014
Hoggart, CJ; Venturini, G; Mangino, M; Gomez, F; Ascari, G; Zhao, JH; Teumer, A; Winkler, TW; Tsernikova, N; Luan, J; Mihailov, E; Ehret, GB; Zhang, W; Lamparter, D; Esko, T; Mace, A; Rueger, S; Bochud, P-Y; Barcella, M; Dauvilliers, Y ... Kutalik, Z. (2014). Novel Approach Identifies SNPs in SLC2A10 and KCNK9 with Evidence for Parent-of-Origin Effect on Body Mass Index. Plos Genetics, 10 (7), e1004508.10.1371/journal.pgen.1004508.
1.1.
2013
Tammiste, Anu; Jiang, Tao; Fischer, Krista; Mägi, Reedik; Krjutškov, Kaarel; Pettai, Kristi; Esko, Tõnu; Li, Yingrui; Tansey, Katherine E; Carroll, Liam S; Uher, Rudolf; McGuffin, Peter; Võsa, Urmo; Tšernikova, Natalia; Saria, Alois; Ng, Pauline C; Eller, Triin; Vasar, Veiko; Nutt, David J; Maron, Eduard ... Metspalu, Andres (2013). Whole-exome sequencing identifies a polymorphism in the BMP5 gene associated with SSRI treatment response in major depression. Journal of Psychopharmacology, 27 (10), 915−920.10.1177/0269881113499829.
15.05.2019
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  • Found 3 results
ProgramTypeNumberNameProject startProject endPrincipal investigatorInstitutionFinancing
SFSF0180142As08Genetic variations, lifestyle and environmental factors in shaping the human health01.01.200831.12.2013Neeme TõnissonUniversity of Tartu; University of Tartu, Faculty of Science and Technology (old), Institute of Molecular and Cell Biology, University of Tartu536 490,12 EUR
TKSLTMR16142T (TK142)Centre of Excellence for Genomics and Translational Medicine (TK142)01.01.201601.03.2023Andres MetspaluUniversity of Tartu, Estonian Genome Center 4 474 349,50 EUR
IUTIUT20-60Omics for health: an integrated approach to understand and predict human disease01.01.201431.12.2019Andres MetspaluUniversity of Tartu, Estonian Genome Center ; University of Tartu, Institute of Genomics1 327 800,00 EUR