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David William Schryer

https://www.etis.ee/CV/David William_Schryer/est
15.07.1975
+372 517 6922
schryer@ut.ee
Systems biology researcher who writes software to analyze proteomics data, next-generation sequencing data, and to perform steady-state and dynamic metabolic flux analysis.

Teenistuskäik

Töökohad ja ametid
2013–...   
Tartu Ülikool, Loodus- ja tehnoloogiateaduskond, Tartu Ülikooli Tehnoloogiainstituut, Computational biologist (1,00)
2008–2013   
Tallinna Tehnikaülikool, TTÜ Küberneetika Instituut, insener (1,00)
01.09.2007–2008   
Tallinna Tehnikaülikool, TTÜ Küberneetika Instituut, Assistent (1,00)
2006–2008   
AS Toidu- ja Fermentatsioonitehnoloogia Arenduskeskus, Researcher (1,00)
2005–2006   
Tallinna Tehnikaülikool, Keemia ja materjalitehnoloogia teaduskond, Keemiatehnika instituut, insener (0,50)
01.01.2005–31.12.2006   
Estonian Business School, Teacher of chemistry, physics, and computer science
01.01.2000–31.12.2003   
University of Toronto, Department of Chemical Engineering, Graduate Teaching Assistant
01.01.1999–31.12.2004   
University of Toronto, Department of Chemical Engineering, Laboratory of Professor C.A.Mims, Research Assistant
01.01.1998–31.12.1999   
McAsphalt Engineering Services, Toronto, Ontario, Canada, Research Assistant
 
 
Haridustee
2007–2012   
Tallinn University of Technology, PhD, Technical Physics -- Awaiting defense on April 12, 2012
2002–2005   
University of Toronto, M.A.Sc., Chemical Engineering
1997–2000   
University of Toronto, B.A.Sc., Chemical Engineering
 
 
Teadusorganisatsiooniline ja -administratiivne tegevus
2001−2002   
University of Toronto, Graduate Students’ Union Executive
2001−2002   
University of Toronto, Hart House, Member of the Board of Stewards
1999−2003   
University of Toronto, Department of Chemical Engineering, CEGSA Executive

Kvalifikatsioon

Teaduskraadid
David William Schryer, doktorikraad, 2013, (juh) Marko Vendelin; Toomas Paalme; Pearu Peterson, Metabolic Flux Analysis of Compartmentalized Systems using Dynamic Isotopologue Modeling (Metabolic Flux Analysis of Compartmentalized Systems using Dynamic Isotopologue Modeling), Tallinna Tehnikaülikool, TTÜ Küberneetika Instituut, Süsteemibioloogia laboratoorium.
David William Schryer, magistrikraad (teaduskraad), 2005, (juh) C.A.Mims, On the determination of sub-second water–cellulose sorption kinetics using mass (On the determination of sub-second water–cellulose sorption kinetics using mass), University of Toronto, Department of Chemical Engineering.
 
 
Teaduspreemiad ja tunnustused
2003, David William Schryer, University of Toronto Fellowship - $1200
2002, David William Schryer, University of Toronto Fellowship - $1200
2001, David William Schryer, OGSST Scholarship $15000
2000, David William Schryer, Best Plant Design Project 2000
1998, David William Schryer, Undergraduate Achievment Scholarship - $1500
1997, David William Schryer, Undergraduate Achievment Scholarship - $1500
 
 
Teadustöö põhisuunad
ETIS KLASSIFIKAATOR: 4. Loodusteadused ja tehnika; 4.16. Biotehnoloogia (loodusteadused ja tehnika); TÄPSUSTUS: Computational Systems Biology and development of technology for 13C labeling experiments.
ETIS KLASSIFIKAATOR: 3. Terviseuuringud; 3.11. Terviseuuringutega seotud uuringud, näiteks biokeemia, geneetika, mikrobioloogia, biotehnoloogia, molekulaarbioloogia, rakubioloogia, biofüüsika ja bioinformaatika; CERCS KLASSIFIKAATOR: B130 Füsioloogiline biofüüsika
ETIS KLASSIFIKAATOR: 1. Bio- ja keskkonnateadused; 1.12. Bio- ja keskkonnateadustega seotud uuringud, näiteks biotehnoloogia, molekulaarbioloogia, rakubioloogia, biofüüsika, majandus- ja tehnoloogiauuringud; CERCS KLASSIFIKAATOR: B110 Bioinformaatika, meditsiiniinformaatika, biomatemaatika, biomeetrika ; TÄPSUSTUS: Analysis of next-generation sequencing data.
ETIS KLASSIFIKAATOR: 1. Bio- ja keskkonnateadused; 1.2. Mikrobioloogia; CERCS KLASSIFIKAATOR: B230 Mikrobioloogia, bakterioloogia, viroloogia, mükoloogia ; TÄPSUSTUS: Analysis of metabolic systems.
ETIS KLASSIFIKAATOR: 1. Bio- ja keskkonnateadused; 1.1. Biokeemia; CERCS KLASSIFIKAATOR: P310 Proteiinid, ensümoloogia; TÄPSUSTUS: Analysis of proteomic data.

Lõppenud projektid

Publikatsioonid

Klass
Aasta
Publikatsioon
 
1.1.
2012
Schryer, David W.; Peterson, Pearu; Illaste, Ardo; Vendelin, Marko (2012). Sensitivity analysis of flux determination in heart by H(2) (18)O -provided labeling using a dynamic isotopologue model of energy transfer pathways. PLoS Computational Biology, 8 (12), e1002795, 1−15.10.1371/journal.pcbi.1002795.
2.3.
2012
Schryer, David W. (2012). Metabolic flux analysis of compartmentalized systems using dynamic isotopologue modeling. (Doktoritöö, Tallinn University of Technology, Institute of Cybernetics). Tallinn: TUT Press.
5.1.
2012
Schryer, D.W.; Peterson, P.; Illaste, A.; Vendelin, M. (2012). Mathematical model of oxygen labeling to study heart energy transfer. Biophysical Journal, 102, 141a−141a. DOI: 10.1016/j.bpj.2011.11.777.
1.1.
2011
Schryer, David W.; Vendelin, Marko; Peterson, Pearu (2011). Symbolic flux analysis for genome-scale metabolic networks. BMC Systems Biology, 5, Articel 81.10.1186/1752-0509-5-81.
1.1.
2010
Illaste, Ardo; Kalda, Mari; Schryer, David W.; Sepp, Mervi (2010). Life of mice - development of cardiac energetics. The Journal of Physiology, 588 (23), 4617−4619.10.1113/jphysiol.2010.199901.
5.1.
2010
Illaste, A.; Schryer, D.W.; Birkedal, R.; Peterson, P; Vendelin, M. (2010). Determination of regional diffusion coefficients of fluorescent ATP in rat cardiomyocytes. Biophysical Journal, 98, 749a−749a. DOI: 10.1016/j.bpj.2009.12.4107.
1.1.
2009
Schryer, David W.; Peterson, Pearu; Paalme, Toomas; Vendelin, Marko (2009). Bidirectionality and compartmentation of metabolic fluxes are revealed in the dynamics of isotopomer networks. International Journal of Molecular Sciences, 10 (4), 1697−1718. DOI: 10.3390/ijms10041697.
5.2.
2009
Schryer, David W.; Peterson, Pearu; Paalme, Toomas; Vendelin, Marko (2009). Isotopomeric 13C labeling of amino acids reveal compartmentation in Saccharomyces uvarum. Biophysical Journal, 96, 308a. DOI: 10.1016/j.bpj.2008.12.1537.
5.2.
2001
Schryer, David; Diamond, Miriam; Liu, Qintao; Stern, Gary; McCarry, Brian (2001). Multimedia urban model: validation and uncertainty analysis using a dynamic Monte Carlo method. SETAC 22nd Annual Meeting : Baltimore Convention Center, 11 - 15 November 2001Baltimore, Maryland, USA. Pensacola: Setac, [1].
25.11.2020

David William Schryer

https://www.etis.ee/CV/David William_Schryer/eng
15.07.1975
+372 517 6922
schryer@ut.ee
Systems biology researcher who writes software to analyze proteomics data, next-generation sequencing data, and to perform steady-state and dynamic metabolic flux analysis.

Career

Institutions and positions
2013–...   
University of Tartu, Faculty of Science and Technology (old), Institute of Technology, University of Tartu, Computational biologist (1,00)
2008–2013   
Tallinn University of Technology , Institute of Cybernetics at TUT, Engineer (1,00)
01.09.2007–2008   
Tallinn University of Technology , Institute of Cybernetics at TUT, Assistant (1,00)
2006–2008   
Center of Food and Fermentation Technologies, Researcher (1,00)
2005–2006   
Tallinn University of Technology , Faculty of Chemical and Materials Technology, Department of Chemical Engineering, Other staff (0,50)
01.01.2005–31.12.2006   
Estonian Business School, Teacher of chemistry, physics, and computer science
01.01.2000–31.12.2003   
University of Toronto, Department of Chemical Engineering, Graduate Teaching Assistant
01.01.1999–31.12.2004   
University of Toronto, Department of Chemical Engineering, Laboratory of Professor C.A.Mims, Research Assistant
01.01.1998–31.12.1999   
McAsphalt Engineering Services, Toronto, Ontario, Canada, Research Assistant
 
 
Education
2007–2012   
Tallinn University of Technology, PhD, Technical Physics -- Awaiting defense on April 12, 2012
2002–2005   
University of Toronto, M.A.Sc., Chemical Engineering
1997–2000   
University of Toronto, B.A.Sc., Chemical Engineering
 
 
R&D related managerial and administrative work
2001−2002   
University of Toronto, Graduate Students’ Union Executive
2001−2002   
University of Toronto, Hart House, Member of the Board of Stewards
1999−2003   
University of Toronto, Department of Chemical Engineering, CEGSA Executive

Qualifications

Academic degrees
David William Schryer, Doctor's Degree, 2013, (sup) Marko Vendelin; Toomas Paalme; Pearu Peterson, Metabolic Flux Analysis of Compartmentalized Systems using Dynamic Isotopologue Modeling, Tallinn University of Technology Institute of Cybernetics at TUT, Laboratory of Systems Biology.
David William Schryer, Research Master's Degree, 2005, (sup) C.A.Mims, On the determination of sub-second water–cellulose sorption kinetics using mass, University of Toronto, Department of Chemical Engineering.
 
 
Honours & awards
2003, David William Schryer, University of Toronto Fellowship - $1200
2002, David William Schryer, University of Toronto Fellowship - $1200
2001, David William Schryer, OGSST Scholarship $15000
2000, David William Schryer, Best Plant Design Project 2000
1998, David William Schryer, Undergraduate Achievment Scholarship - $1500
1997, David William Schryer, Undergraduate Achievment Scholarship - $1500
 
 
Fields of research
ETIS CLASSIFICATION: 4. Natural Sciences and Engineering; 4.16. Biotechnology relating to Natural Sciences and Engineering; SPECIFICATION: Computational Systems Biology and development of technology for 13C labeling experiments.
ETIS CLASSIFICATION: 3. Health; 3.11. Biochemistry, Genetics, Microbiology, Biotechnology, Molecular Biology, Cell Biology, Biophysics and Bioinformatics relating to Health Studies; CERCS CLASSIFICATION: B130 Physiological biophysics
ETIS CLASSIFICATION: 1. Biosciences and Environment; 1.12. Biotechnology, Molecular Biology, Cell Biology, Biophysics and Economic and Technological Research relating to Bio- and Environmental Sciences; CERCS CLASSIFICATION: B110 Bioinformatics, medical informatics, biomathematics, biometrics ; SPECIFICATION: Analysis of next-generation sequencing data.
ETIS CLASSIFICATION: 1. Biosciences and Environment; 1.2. Microbiology; CERCS CLASSIFICATION: B230 Microbiology, bacteriology, virology, mycology ; SPECIFICATION: Analysis of metabolic systems.
ETIS CLASSIFICATION: 1. Biosciences and Environment; 1.1. Biochemistry; CERCS CLASSIFICATION: P310 Proteins, enzymology ; SPECIFICATION: Analysis of proteomic data.
 
 

Completed projects

Publications

Category
Year
Publication
 
1.1.
2014
Kannan, K.; Kanabar, P.; Schryer, D.; Florin, T.; Oh, E.; Bahroos, N.; Tenson, T.; Weissman, J.S.; Mankin, A.S. (2014). The general mode of translation inhibition by macrolide antibiotics. Proceedings of the National Academy of Sciences, 45 (111), 15958−15963. DOI: 10.1073/pnas.1417334111.
1.1.
2012
Schryer, David W.; Peterson, Pearu; Illaste, Ardo; Vendelin, Marko (2012). Sensitivity analysis of flux determination in heart by H(2) (18)O -provided labeling using a dynamic isotopologue model of energy transfer pathways. PLoS Computational Biology, 8 (12), e1002795, 1−15.10.1371/journal.pcbi.1002795.
2.3.
2012
Schryer, David W. (2012). Metabolic flux analysis of compartmentalized systems using dynamic isotopologue modeling. (Doktoritöö, Tallinn University of Technology, Institute of Cybernetics). Tallinn: TUT Press.
5.1.
2012
Schryer, D.W.; Peterson, P.; Illaste, A.; Vendelin, M. (2012). Mathematical model of oxygen labeling to study heart energy transfer. Biophysical Journal, 102, 141a−141a. DOI: 10.1016/j.bpj.2011.11.777.
1.1.
2011
Schryer, David W.; Vendelin, Marko; Peterson, Pearu (2011). Symbolic flux analysis for genome-scale metabolic networks. BMC Systems Biology, 5, Articel 81.10.1186/1752-0509-5-81.
1.1.
2010
Illaste, Ardo; Kalda, Mari; Schryer, David W.; Sepp, Mervi (2010). Life of mice - development of cardiac energetics. The Journal of Physiology, 588 (23), 4617−4619.10.1113/jphysiol.2010.199901.
5.1.
2010
Illaste, A.; Schryer, D.W.; Birkedal, R.; Peterson, P; Vendelin, M. (2010). Determination of regional diffusion coefficients of fluorescent ATP in rat cardiomyocytes. Biophysical Journal, 98, 749a−749a. DOI: 10.1016/j.bpj.2009.12.4107.
1.1.
2009
Schryer, David W.; Peterson, Pearu; Paalme, Toomas; Vendelin, Marko (2009). Bidirectionality and compartmentation of metabolic fluxes are revealed in the dynamics of isotopomer networks. International Journal of Molecular Sciences, 10 (4), 1697−1718. DOI: 10.3390/ijms10041697.
5.2.
2009
Schryer, David W.; Peterson, Pearu; Paalme, Toomas; Vendelin, Marko (2009). Isotopomeric 13C labeling of amino acids reveal compartmentation in Saccharomyces uvarum. Biophysical Journal, 96, 308a. DOI: 10.1016/j.bpj.2008.12.1537.
5.2.
2001
Schryer, David; Diamond, Miriam; Liu, Qintao; Stern, Gary; McCarry, Brian (2001). Multimedia urban model: validation and uncertainty analysis using a dynamic Monte Carlo method. SETAC 22nd Annual Meeting : Baltimore Convention Center, 11 - 15 November 2001Baltimore, Maryland, USA. Pensacola: Setac, [1].
25.11.2020

Otsi projekti

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Uus ja vana Frascati (otsing uue järgi väljastab ka seotud vanad)
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