See veebileht kasutab küpsiseid kasutaja sessiooni andmete hoidmiseks. Veebilehe kasutamisega nõustute ETISe kasutustingimustega. Loe rohkem
Olen nõus

Merit Pauskar

https://www.etis.ee/CV/Merit_Pauskar/est
14.06.1986
merit.pauskar@ut.ee

Teenistuskäik

Töökohad ja ametid
01.07.2019–30.06.2024   
Tartu Ülikool, Meditsiiniteaduste valdkond, bio- ja siirdemeditsiini instituut, meditsiinilise viroloogia nooremteadur (1,00)
01.01.2016–...   
Tartu Ülikool, Meditsiiniteaduste valdkond, bio- ja siirdemeditsiini instituut, spetsialist (1,00)
01.12.2017–30.06.2019   
Tartu Ülikool, Meditsiiniteaduste valdkond, bio- ja siirdemeditsiini instituut, spetsialist (1,00)
01.06.2014–31.12.2015   
Tartu Ülikool, Arstiteaduskond, Mikrobioloogia instituut, spetsialist (1,00)
01.02.2009–31.05.2014   
Tartu Ülikool, Arstiteaduskond, Mikrobioloogia instituut, laborant (1,00)
01.01.2007–31.01.2009   
Tartu Ülikool, Arstiteaduskond, Mikrobioloogia instituut, laborant (0,30)
 
 
Haridustee
2011–2013   
Tartu Ülikool, Arstiteaduskond, Tervishoiu instituut
2005–2009   
Tartu Tervishoiu Kõrgkool
2002–2005   
Tartu Tamme Gümnaasium

Kvalifikatsioon

Teaduskraadid
Merit Pauskar, magistrikraad, 2013, (juh) Kristi Huik; Radko Avi, HIV-1 ülekanduv ravimresistentsus 2010. aastal HIV positiivseks diagnoositute hulgas Eestis, Tartu Ülikool, Arstiteaduskond, Tervishoiu instituut, Epidemioloogia ja biostatistika õppetool.
 
 

Lõppenud projektid

Publikatsioonid

Klass
Aasta
Publikatsioon
 
1.1.
2019
Huik, Kristi; Soodla, Pilleriin; Pauskar, Merit; Owen, S. Michele; Luo, Wei; Murphy, Gary; Jogeda, Ene-Ly; Kallas, Eveli; Rajasaar, Heli; Avi, Radko; Masciotra, Silvina; Lutsar, Irja; Del Amo, Julia; Meyer, Laurence; Bucher, Heiner C.; Chene, Genevieve; Hamouda, Osamah; Pillay, Deenan; Prins, Maria; Rosinska, Magda ... Scott, Martin (2019). The concordance of the limiting antigen and the Bio-Rad avidity assays in persons from Estonia infected mainly with HIV-1 CRF06_cpx. PLoS ONE, 14 (5), ARTN e0217048. DOI: 10.1371/journal.pone.0217048.
1.1.
2019
Soodla, Pilleriin; Huik, Kristi; Pauskar, Merit; Cuypers, Lize; Van Laethem, Kristel; Rajasaar, Heli; Kallas, Eveli; Lepa, Helen; Velts-Lindh, Anna; Jogeda, Ene-Ly; Lutsar, Irja; Avi, Radko (2019). Stable level of HIV transmitted drug resistance in Estonia despite significant scale-up of antiretroviral therapy. Infection Genetics and Evolution, 75, ARTN 103901. DOI: 10.1016/j.meegid.2019.05.019.
1.1.
2018
Jõgeda, E-L; Avi, R; Pauskar, M; Kallas, E; Karki, T; Des Jarlais, D; Uusküla, A; Toompere, K; Lutsar, I; Huik, K (2018). Association of IFNλ4 rs12979860 polymorphism with the acquisition of HCV and HIV infections among people who inject drugs. Journal of Medical Virology, 90 (11), 1779−1783. DOI: 10.1002/jmv.25258.
1.1.
2018
P Soodla, R Simmons, K Huik, M Pauskar, E-L Jõgeda, H Rajasaar, E Kallaste, M Maimets, R Avi, G Murphy, K Porter, I Lutsar and for the Concerted Action on SeroConversion to AIDS and Death in Europe (CASCADE) Collaboration in EuroCoord (2018). HIV incidence in the Estonian population in 2013 determined using the HIV-1 limiting antigen avidity assay. HIV Medicine, 19 (1), 33−41.10.1111/hiv.12535.
1.1.
2017
Jogeda, Ene-Ly; Huik, Kristi; Pauskar, Merit; Kallas, Eveli; Karki, Tonis; Jarlais, Don Des; Uuskula, Anneli; Lutsar, Irja; Avi, Radko (2017). Prevalence and Genotypes of GBV-C and Its Associations With HIV Infection Among Persons Who Inject Drugs in Eastern Europe. Journal of Medical Virology, 89 (4), 632−638.10.1002/jmv.24683.
5.1.
2017
Avi1, R.; Pauskar2, M.; Rajasaar3, H.; Kallas4, E.; Jogeda5, E.; Soodla6, P.; Lutsar7, I. (2017). VIROLOGICAL RESPONSE TO ANTIRETROVIRAL TREATMENT IN AN EASTERN EUROPEAN COHORT STUDY. CROI Foundation/IAS–USA,.
5.1.
2017
Pauskar, M.; Raag, M.; Loigu, K; Pärna, K.; Huik, K. (2017). Are polymorphisms in VMAT1 and CHRNAB3 associated with nicotine dependence in physicians in Estonia? European Journal of Public Health, 27. Elsevier. DOI: 10.1093/eurpub/ckx186.054.
5.2.
2017
Pauskar, M; Raag, M; Loigu, K; Pärna, K; Huik, K; (2017). Are CHRNA5 rs16969968 genotypes associated with nicotine dependence among physicians in Estonia? European Human Genetics Conference, 27–30. May, 2017. European Society of Human Genetics, 1.
1.1.
2016
Huik, Kristi; Avi, Radko; Pauskar, Merit; Kallas, Eveli; Jõgeda, Ene-Ly; Karki, Tõnis; Rüütel, Kristi; Talu, Ave; Abel-Ollo, Katri; Uusküla, Anneli; Carrillo, Andrew; Ahuja, Sunil K; He, Weijing; Lutsar, Irja (2016). A CCL5 Haplotype Is Associated with Low Seropositivity Rate of HCV Infection in People Who Inject Drugs. PLoS ONE, 11 (6), e0156850−e0156850. DOI: 10.1371/journal.pone.0156850.
1.1.
2016
Avi, Radko; Pauskar, Merit; Karki, Tõnis; Kallas, Eveli; Jõgeda, Ene-Ly; Margus, Tõnu; Huik, Kristi; Lutsar, Irja (2016). Prevalence of drug resistance mutations in HAART patients infected with HIV-1 CRF06_cpx in Estonia. Journal of Medical Virology, 88 (3), 448−454. DOI: 10.1002/jmv.24361.
1.1.
2016
Kallas, Eveli; Huik, Kristi; Türk, Silver; Pauskar, Merit; Jõgeda, Ene-Ly; Šunina, Marina; Karki, Tõnis; Des Jarlais, Don; Uusküla, Anneli; Avi, Radko; Lutsar, Irja (2016). T Cell Distribution in Relation to HIV/HBV/HCV Coinfections and Intravenous Drug Use. Viral Immunology, 0−0. DOI: 10.1089/vim.2016.0057.
1.1.
2016
Kallas, Eveli; Huik, Kristi; Türk, Silver; Pauskar, Merit; Jõgeda, Ene-Ly; Šunina, Marina; Karki, Tõnis; Des Jarlais, Don; Uusküla, Anneli; Avi, Radko; Lutsar, Irja (2016). Differences in T cell distribution and CCR5 expression in HIV-positive and HIV-exposed seronegative persons who inject drugs. Medical microbiology and immunology, 205 (3), 231−239. DOI: 10.1007/s00430-015-0444-8.
1.1.
2016
Jõgeda, Ene-Ly; Avi, Radko; Pauskar, Merit; Kallas, Eveli; Karki, Tõnis; Des Jarlais, Don; Uusküla, Anneli; Lutsar, Irja; Huik, Kristi (2016). Human T-lymphotropic virus types 1 and 2 are rare among intravenous drug users in Eastern Europe. Infection Genetics and Evolution, 43, 83−85.10.1016/j.meegid.2016.05.022.
1.1.
2015
Koljalg, Siiri; Telling, Kaidi; Huik, Kristi; Murruste, Marko; Saarevet, Virve; Pauskar, Merit; Lutsar, Irja (2015). First report of Wohlfahrtiimonas chitiniclastica from soft tissue and bone infection at an unusually high northern latitude. Folia Microbiologica, 60 (2), 155−158.10.1007/s12223-014-0355-x.
5.2.
2015
Jõgeda, Ene-Ly; Avi, Radko; Pauskar, Merit; Kallas, Eveli; Karki, Tõnis; Jarlais, Don Des; Uusküla, Anneli; Lutsar, Irja; Huik, Kristi; (2015). HTLV-1/2 is rare among Eastern-European intravenous drug users (IDUs). Retrovirology, 12, P79−P79. DOI: doi.org/10.1186/1742-4690-12-S1-P79.
1.1.
2014
Avi, R; Huik, K; Pauskar, M; Ustina, V; Karki, T; Kallas, E; Jõgeda, EL; Krispin, T; Lutsar, I (2014). Transmitted drug resistance is still low in newly diagnosed human immunodeficiency virus type 1 CRF06_cpx-infected patients in Estonia in 2010. Aids Research and Human Retroviruses, 30 (3), 278−283.10.1089/aid.2012.0357.
1.1.
2014
Huik, K.; Avi, R.; Uibopuu, H.; Pauskar, M.; Margus, T.; Karki, T.; Krispin, T.; Kool, P.; Rüütel, K.; Talu, A.; Abel-Ollo, K.; Uusküla, A.; Carrillo, AQ.; He, W.; Ahuja, SK.; Lutsar, I. (2014). Association between HIV-1 tropism and CCR5 human haplotype E in a Caucasian population. Jaids-Journal of Acquired Immune Deficiency Syndromes, 66 (3), 239−244. DOI: 10.1097/QAI.0000000000000127.
5.2.
2014
Avi, R.; Huik, K.; Pauskar, M.; Kallas, E.; Jõgeda, E.-L.; Zilmer, K.; Ustina, V.; Novikova, L.; Karki, T.; Kisand, V.; Lutsar, I. (2014). Full-Length Genome Sequences of Estonian HIV-1 CRF06 and Eastern-European Subtype A1 Recombinant Forms. 7th National Congress HIV/AIDS and the 2nd Central European HIV Forum, Sibiu, Romania, 29-31 May 2014.
5.2.
2014
Pauskar, M.; Huik, K.; Avi, R.; Kallas, E.; Jõgeda, E.-L.; Karki, T.; Semjonova, S.; Smidt, J.; Novikova, L.; Ainsalu, K.; Lutsar, I. (2014). Antiretroviral drug resistance and viral tropism in HIV-1 CRF06_cpx infected patients failing antiretroviral (ARV) therapy. 7th National Congress HIV/AIDS and the 2nd Central European HIV Forum, Sibiu, Romania, 29-31 May 2014.
5.2.
2014
Kallas, E.; Huik, K.; Avi, R; Pauskar, M.; Jõgeda, E.-L.; Karki, T.; Marsh, K.; Des Jarlais, D.; Uusküla, A.; Lutsar, I. (2014). NLRP3 genotype CG increases the risk of HIV-1 in Caucasian intravenous drug users (IDUs). European Human Genetics Conference 2014, Milan, Italy, 31 May-3 June 2014.
5.2.
2014
Jõgeda, E.-L.; Huik, K.; Avi, R; Pauskar, M., Kallas, E.; Karki, T.; Marsh, K.; Des Jarlais, D.; Uusküla, A.; Lutsar, I. (2014). Associations between MX2 polymorphism and the acquisition of HIV and co-infections in Caucasian intravenous drug users (IDUs). European Human Genetics Conference 2014, Milan, Italy, 31 May-3 June 2014.
5.2.
2014
Kallas, E.; Avi, R.; Huik, K.; Türk, S.; Pauskar, M.; Jõgeda, E.-.L.; Šunina, M.; Des Jarlais, D.; Uusküla, A.; Lutsar, I. (2014). Injection drug use influences T-cell distribution and CCR5 expression in HIV+ and ESN population. 24th European Congress of Clinical Microbiology and Infectious Diseases; Barcelona; 10-13 May 2014.
1.1.
2013
Huik, K; Avi, R; Pauskar, M; Kallas, E; Jõgeda, EL; Karki, T; Marsh, K; Des Jarlais, D; Uusküla, A; Lutsar, I (2013). Association between TLR3 rs3775291 and resistance to HIV among highly exposed Caucasian intravenous drug users. Infection Genetics and Evolution, 20, 78−82.10.1016/j.meegid.2013.08.008.
1.1.
2013
Huik, K; Avi, R; Carrillo, A; Harper, N; Pauskar, M; Sadam, M; Karki, T; Krispin, T; He, W; Lutsar, I (2013). CCR5 Haplotypes Influence HCV Serostatus in Caucasian Intravenous Drug Users. PLoS ONE, 8 (7), e70561. DOI: 10.1371/journal.pone.0070561.
5.2.
2013
Avi, Radko; Huik, Kristi; Pauskar, Merit; Kallas, Eveli; Jõgeda, Ene-Ly; Karki, Tõnis; Šmidt, Jelena; Novikova, Lilia; Semjonova, Svetlana; Lutsar, Irja. (2013). Substitutions in RNaseH and Connection domain of HIV-1 CRF06_cpx viruses in treatment naive and treatment experienced populations. 11th European Meeting on HIV & Hepatitis- Treatment Strategies & Antiviral Drug Resistance; Rome; 20-22 March 2013. 35−35.
5.2.
2013
Kallas, Eveli; Huik, Kristi; Av1, Radko; Pauskar, Merit; Jõgeda, Ene-Ly; Karki, Tõnis; Marsh, Kristina; Des Jarlais, Don; Uusküla, Anneli; Lutsar, Irja (2013). The IL-10 promoter genotype AA at -592 is correlated with increased susceptibility to hepatitis B but not HIV infection in Caucasian intravenous drug users. European Human Genetics Conference 2013, Paris, France, 8.06.13-11.06.13.
5.2.
2013
Jõgeda, Ene-Ly; Huik, Kristi; Pauskar, Merit; Kallas, Eveli; Krispin, Tõnu; Karki, Tõnis; Marsh, Kristina; Des Jarlais, Don; Uusküla, Anneli; Avi, Radko; Lutsar, Irja. (2013). The prevalence of GBV-C and its associations with HIV infection among Estonian intravenous drug users. Reviews in Antiviral Therapy Infectious Diseases: 11th European Meeting on HIV & Hepatitis- Treatment Strategies & Antiviral Drug Resistance; Rome; 20-22 March 2013. 46−47.
5.2.
2013
Parm, Ü.; Metsvaht, T.; Ilmoja, ML.; Pauskar, M.; Lutsar, I. (2013). Associations between feeding regimen, mucosal colonization and prevalence of sepsis in neonates admitted to neonatal intensive care unit (NICU). ECCMID; European Congress on Clinical Microbiology and Infectious Diseases; Berlin, Germany; April 27-30, 2013.. Konverentsi kogumik, X−X.
1.1.
2012
Soeorg, H.; Tamm, E.; Huik, K.; Pauskar, M.; Mägi, D.; Pruudel, K.; Vainomäe, L.; Moosar, L.; Kirss, K.; Torm, S.; Närska, M.; Pütsepp, A.; Nurm, H.; Pruunsild, K.; Jänes, A.; Zilmer, K.; Lutsar, I. (2012). Group A rotavirus genotypes circulating prior to implementation of a National Immunization Program in Estonia. Human Vaccines, 8 (4), 465−469.10.4161/hv.19135.
5.2.
2012
Avi, R.; Huik, K.; Pauskar, M., Lutsar, I.; Vandamme, A.; Abecasis, A. (2012). The population dynamics of the HIV-1 epidemic in Estonia through virus genetic analysis and national case recording. 17th International BioInformatics Workshop on Virus Evolution and Molecular Epidemiology, 27-31 August 2012 Belgrade Serbia.
5.2.
2012
Pauskar, M.; Avi, R.; Huik, K.; Ustina, V.; Jõgeda, E.; Kallas, E.; Karki, T.; Krispin, T.; Lutsar, I. (2012). Transmitted drug resistance is 4.5% in newly diagnosed mainly HIV-1 CRF06_cpx infected patients in Estonia in 2010. 10th European Meeting on HIV & Hepatitis - Treatment Strategies & Antiviral Drug Resistance, 28 - 30 March 2012 Barcelona Spain.
5.2.
2012
Kallas, E.; Avi, R.; Huik, K.; Pauskar, M.; Ustina, V.; Karki, T.; Krispin, T.; Ainsalu, K.; Semjonova, S.; Kool, P.; Novikova, L.; Schmidt, J.; Lutsar, I. (2012). HIV Type-1 CRF06_cpx P(T/S)AP Late Domain duplications are outselected among treatment experienced compared to treatment naïve patients. Reviews in Antiviral Therapy & Infectious Diseases. ,.
5.2.
2012
Avi, R.; Huik, K.; Pauskar, M.; Kallas, E.; Karki, T.; Krispin, T.; Ainsalu, K.; Semjonova, S.; Kool, P.; Novikova, L.; Schmidt, J.; Lutsar, I. (2012). The pattern of drug resistance mutations in HIV-1 CRF06_cpx viruses failing the first-line NNRTI+2NRTI antiretroviral therapy. 10th European Meeting on HIV & Hepatitis - Treatment Strategies & Antiviral Drug Resistance, 28 - 30 March 2012 Barcelona Spain.
5.2.
2012
Uibopuu, H.; Huik, K.; Avi, R.; Pauskar, M.; Kallas, E.; Karki, T.; Krispin, T.; Kool, P.; Schmidt, J.; Rüütel, K.; Talu, A.; Abel-Ollo, K.; Uusküla, A.; Lutsar, I. (2012). Viral tropism of HIV-1 CRF06_cpx and its association with CCR5 haplotypes. 10th European Meeting on HIV & Hepatitis - Treatment Strategies & Antiviral Drug Resistance, 28 - 30 March 2012 Barcelona Spain.
5.2.
2012
Soeorg, Hiie; Huik, Kristi; Štšepetova, Jelena; Truusalu, Kai; Pauskar, Merit; Parm, Ülle; Ilmoja, Mari-Liis; Metsvaht, Tuuli; Lutsar, Irja (2012). Genetic relatedness of coagulase-negative staphylococci (CoNS) from gastrointestinal tract (GIT) and blood of neonates with late-onset sepsis (LOS). The 30th Annual Meeting of the European Society for Paediatric Infectious Diseases, May 8-12, 2012, Thessaloniki, Greece..
1.1.
2011
Avi, R; Huik, K; Pauskar, M; Ustina, V; Karki, T; Krispin, T; Ainsalu, K; Paap, P; Schmidt, J; Nikitina, N; Lutsar, I. (2011). Emerging Transmitted Drug Resistance in Treatment Naive Human Immunodeficiency Virus - 1 CRF06_cpx Infected Patients in Estonia. Scandinavian Journal of Infectious Diseases, 43 (2), 122−128.
1.1.
2011
Parm, U.; Metsvaht, T.; Sepp, E.; Ilmoja, ML.; Pisarev, H.; Pauskar, M.; Lutsar, I. (2011). Risk factors associated with gut and nasopharyngeal colonization by common Gram-negative species and yeasts in neonatal intensive unit patients. Early Human Development, 87 (6), 391−399.10.1016/j.earlhumdev.2011.02.007.
1.1.
2011
Parm, U.; Metsvaht, T.; Sepp, E.; Ilmoja, ML.; Pisarev, H.; Pauskar, M.; Lutsar, I. (2011). Mucosal surveillance cultures in predicting Gram-negative late-onset sepsis in neonatal intensive care units. Journal of Hospital Infection, 78 (4), 327−332.10.1016/j.jhin.2011.03.025.
5.2.
2011
Parm, U.; Metsvaht, T.; Sepp, E.; Ilmoja, ML.; Pisarev, H.; Pauskar, M.; Lutsar, I. (2011). Risk factors associated with gut and nasopharyngeal colonization by common Gram-negative species and yeasts in NICU. European Congress of Clinical Microbiology and Infectious Diseases, Milano, May 7-10, 2011..
1.1.
2010
Parm, Ü.; Metsvaht, T.; Sepp, E.; Ilmoja, ML.; Pisarev, H.; Pauskar, M.; Lutsar, I. (2010). Impact of empiric antibiotic regimen on bowel colonization in neonates with suspected early onset sepsis. European Journal of Clinical Microbiology & Infectious Diseases, 29 (7), 807−816.10.1007/s10096-010-0931-1.
5.2.
2010
Parm, Ülle; Sepp, Epp; Metsvaht, Tuuli; Ilmoja, Mari-Liis; Pruunsild, Kaie; Maipuu, Lea; Pauskar, Merit; Lutsar, Irja. (2010). Relevance of mucosal surveillance cultures in predicting Gram-negative sepsis in neonatal intensive care units (NICU). European Congress of Clinical Microbiology and Infectious Diseases, Vienna 2010..
5.2.
2010
Huik, Kristi; Parm, Ülle; Denks, Kärt; Pauskar, Merit; Lutsar, Irja. (2010). magA, k2A, rmpA and kfu genes are not related to onset neonatal sepsis of Klebsiella pneumoniae in neonatal intensive care units in two major hospitals in Estonia. European Congress of Clinical Microbiology and Infectious Diseases, Vienna 2010..
3.5.
2009
Parm, Ülle; Metsvaht, Tuuli; Sepp, Epp; Pisarev, Heti; Ilmoja, Mari-Liis; Pauskar, Merit; Lutsar, Irja (2009). Impact of empiric antibiotic regimen on bowel colonization in neonates with suspected early onset sepsis. Posterettekanne 16-19 mail 2009 Helsingis (19th ECCMID).
5.2.
2009
Pauskar, M.; Parm, Ü.; Sepp, E.; Metsvaht, T. ; Ilmoja, M.-L.; Lutsar, I. (2009). Gut colonization by Staphylococci in neonates with suspected early onset sepsis influenced by empiric antibiotic therapy. Well-known infections the hottest features of diagnostics and treatment: VIII Nordic-Baltic congress of infectious Diseases; Saint Petersburg, Russia; 23.-26.09.2009. 60.
3.5.
2008
• Parm, Ü; Sepp, E; Metsvaht, T; Ilmoja, M.-L.; Pauskar, M; Kilg, T; Mihhailova, M; Lutsar, I. (2008). Ampitsilliini ja penitsilliini mõju kolonisatsiooni tekkele oportunistlike mikroobidega. Eesti Arst: TÜ Arstiteaduskonna päevadel 9 okt 2008.
13.02.2021

Merit Pauskar

https://www.etis.ee/CV/Merit_Pauskar/eng
14.06.1986
merit.pauskar@ut.ee

Career

Institutions and positions
01.07.2019–30.06.2024   
University of Tartu, Faculty of Medicine, Institute of Biomedicine and Translational Medicine, Junior Research Fellow (1,00)
01.01.2016–...   
University of Tartu, Faculty of Medicine, Institute of Biomedicine and Translational Medicine, Specialist (1,00)
01.12.2017–30.06.2019   
University of Tartu, Faculty of Medicine, Institute of Biomedicine and Translational Medicine, Specialist (1,00)
01.06.2014–31.12.2015   
University of Tartu, Faculty of Medicine, Department of Microbiology, Specialist (1,00)
01.02.2009–31.05.2014   
University of Tartu, Faculty of Medicine, Department of Microbiology, Laboratory Assistant (1,00)
01.01.2007–31.01.2009   
University of Tartu, Faculty of Medicine, Department of Microbiology, Laboratory Assistant (0,30)
 
 
Education
2011–2013   
University of Tartu, Faculty of Medicine, Department of Public Health, Chair of Epidemiology and Biostatistics
2005–2009   
Tartu Health Care Collage
2002–2005   
Tartu Tamme Gymnasium

Qualifications

Academic degrees
Merit Pauskar, Master's Degree, 2013, (sup) Kristi Huik; Radko Avi, HIV-1 ülekanduv ravimresistentsus 2010. aastal HIV positiivseks diagnoositute hulgas Eestis (HIV-1 transmitted drug resistance in newly diagnosed HIV-infected patients in Estonia in 2010), University of Tartu, Faculty of Medicine, Department of Public Health, Chair of Epidemiology and Biostatistics.
 
 

Completed projects

Publications

Category
Year
Publication
 
1.1.
2019
Huik, Kristi; Soodla, Pilleriin; Pauskar, Merit; Owen, S. Michele; Luo, Wei; Murphy, Gary; Jogeda, Ene-Ly; Kallas, Eveli; Rajasaar, Heli; Avi, Radko; Masciotra, Silvina; Lutsar, Irja; Del Amo, Julia; Meyer, Laurence; Bucher, Heiner C.; Chene, Genevieve; Hamouda, Osamah; Pillay, Deenan; Prins, Maria; Rosinska, Magda ... Scott, Martin (2019). The concordance of the limiting antigen and the Bio-Rad avidity assays in persons from Estonia infected mainly with HIV-1 CRF06_cpx. PLoS ONE, 14 (5), ARTN e0217048. DOI: 10.1371/journal.pone.0217048.
1.1.
2019
Soodla, Pilleriin; Huik, Kristi; Pauskar, Merit; Cuypers, Lize; Van Laethem, Kristel; Rajasaar, Heli; Kallas, Eveli; Lepa, Helen; Velts-Lindh, Anna; Jogeda, Ene-Ly; Lutsar, Irja; Avi, Radko (2019). Stable level of HIV transmitted drug resistance in Estonia despite significant scale-up of antiretroviral therapy. Infection Genetics and Evolution, 75, ARTN 103901. DOI: 10.1016/j.meegid.2019.05.019.
1.1.
2018
Jõgeda, E-L; Avi, R; Pauskar, M; Kallas, E; Karki, T; Des Jarlais, D; Uusküla, A; Toompere, K; Lutsar, I; Huik, K (2018). Association of IFNλ4 rs12979860 polymorphism with the acquisition of HCV and HIV infections among people who inject drugs. Journal of Medical Virology, 90 (11), 1779−1783. DOI: 10.1002/jmv.25258.
1.1.
2018
P Soodla, R Simmons, K Huik, M Pauskar, E-L Jõgeda, H Rajasaar, E Kallaste, M Maimets, R Avi, G Murphy, K Porter, I Lutsar and for the Concerted Action on SeroConversion to AIDS and Death in Europe (CASCADE) Collaboration in EuroCoord (2018). HIV incidence in the Estonian population in 2013 determined using the HIV-1 limiting antigen avidity assay. HIV Medicine, 19 (1), 33−41.10.1111/hiv.12535.
1.1.
2017
Jogeda, Ene-Ly; Huik, Kristi; Pauskar, Merit; Kallas, Eveli; Karki, Tonis; Jarlais, Don Des; Uuskula, Anneli; Lutsar, Irja; Avi, Radko (2017). Prevalence and Genotypes of GBV-C and Its Associations With HIV Infection Among Persons Who Inject Drugs in Eastern Europe. Journal of Medical Virology, 89 (4), 632−638.10.1002/jmv.24683.
5.1.
2017
Avi1, R.; Pauskar2, M.; Rajasaar3, H.; Kallas4, E.; Jogeda5, E.; Soodla6, P.; Lutsar7, I. (2017). VIROLOGICAL RESPONSE TO ANTIRETROVIRAL TREATMENT IN AN EASTERN EUROPEAN COHORT STUDY. CROI Foundation/IAS–USA,.
5.1.
2017
Pauskar, M.; Raag, M.; Loigu, K; Pärna, K.; Huik, K. (2017). Are polymorphisms in VMAT1 and CHRNAB3 associated with nicotine dependence in physicians in Estonia? European Journal of Public Health, 27. Elsevier. DOI: 10.1093/eurpub/ckx186.054.
5.2.
2017
Pauskar, M; Raag, M; Loigu, K; Pärna, K; Huik, K; (2017). Are CHRNA5 rs16969968 genotypes associated with nicotine dependence among physicians in Estonia? European Human Genetics Conference, 27–30. May, 2017. European Society of Human Genetics, 1.
1.1.
2016
Huik, Kristi; Avi, Radko; Pauskar, Merit; Kallas, Eveli; Jõgeda, Ene-Ly; Karki, Tõnis; Rüütel, Kristi; Talu, Ave; Abel-Ollo, Katri; Uusküla, Anneli; Carrillo, Andrew; Ahuja, Sunil K; He, Weijing; Lutsar, Irja (2016). A CCL5 Haplotype Is Associated with Low Seropositivity Rate of HCV Infection in People Who Inject Drugs. PLoS ONE, 11 (6), e0156850−e0156850. DOI: 10.1371/journal.pone.0156850.
1.1.
2016
Avi, Radko; Pauskar, Merit; Karki, Tõnis; Kallas, Eveli; Jõgeda, Ene-Ly; Margus, Tõnu; Huik, Kristi; Lutsar, Irja (2016). Prevalence of drug resistance mutations in HAART patients infected with HIV-1 CRF06_cpx in Estonia. Journal of Medical Virology, 88 (3), 448−454. DOI: 10.1002/jmv.24361.
1.1.
2016
Kallas, Eveli; Huik, Kristi; Türk, Silver; Pauskar, Merit; Jõgeda, Ene-Ly; Šunina, Marina; Karki, Tõnis; Des Jarlais, Don; Uusküla, Anneli; Avi, Radko; Lutsar, Irja (2016). T Cell Distribution in Relation to HIV/HBV/HCV Coinfections and Intravenous Drug Use. Viral Immunology, 0−0. DOI: 10.1089/vim.2016.0057.
1.1.
2016
Kallas, Eveli; Huik, Kristi; Türk, Silver; Pauskar, Merit; Jõgeda, Ene-Ly; Šunina, Marina; Karki, Tõnis; Des Jarlais, Don; Uusküla, Anneli; Avi, Radko; Lutsar, Irja (2016). Differences in T cell distribution and CCR5 expression in HIV-positive and HIV-exposed seronegative persons who inject drugs. Medical microbiology and immunology, 205 (3), 231−239. DOI: 10.1007/s00430-015-0444-8.
1.1.
2016
Jõgeda, Ene-Ly; Avi, Radko; Pauskar, Merit; Kallas, Eveli; Karki, Tõnis; Des Jarlais, Don; Uusküla, Anneli; Lutsar, Irja; Huik, Kristi (2016). Human T-lymphotropic virus types 1 and 2 are rare among intravenous drug users in Eastern Europe. Infection Genetics and Evolution, 43, 83−85.10.1016/j.meegid.2016.05.022.
1.1.
2015
Koljalg, Siiri; Telling, Kaidi; Huik, Kristi; Murruste, Marko; Saarevet, Virve; Pauskar, Merit; Lutsar, Irja (2015). First report of Wohlfahrtiimonas chitiniclastica from soft tissue and bone infection at an unusually high northern latitude. Folia Microbiologica, 60 (2), 155−158.10.1007/s12223-014-0355-x.
5.2.
2015
Jõgeda, Ene-Ly; Avi, Radko; Pauskar, Merit; Kallas, Eveli; Karki, Tõnis; Jarlais, Don Des; Uusküla, Anneli; Lutsar, Irja; Huik, Kristi; (2015). HTLV-1/2 is rare among Eastern-European intravenous drug users (IDUs). Retrovirology, 12, P79−P79. DOI: doi.org/10.1186/1742-4690-12-S1-P79.
1.1.
2014
Avi, R; Huik, K; Pauskar, M; Ustina, V; Karki, T; Kallas, E; Jõgeda, EL; Krispin, T; Lutsar, I (2014). Transmitted drug resistance is still low in newly diagnosed human immunodeficiency virus type 1 CRF06_cpx-infected patients in Estonia in 2010. Aids Research and Human Retroviruses, 30 (3), 278−283.10.1089/aid.2012.0357.
1.1.
2014
Huik, K.; Avi, R.; Uibopuu, H.; Pauskar, M.; Margus, T.; Karki, T.; Krispin, T.; Kool, P.; Rüütel, K.; Talu, A.; Abel-Ollo, K.; Uusküla, A.; Carrillo, AQ.; He, W.; Ahuja, SK.; Lutsar, I. (2014). Association between HIV-1 tropism and CCR5 human haplotype E in a Caucasian population. Jaids-Journal of Acquired Immune Deficiency Syndromes, 66 (3), 239−244. DOI: 10.1097/QAI.0000000000000127.
5.2.
2014
Avi, R.; Huik, K.; Pauskar, M.; Kallas, E.; Jõgeda, E.-L.; Zilmer, K.; Ustina, V.; Novikova, L.; Karki, T.; Kisand, V.; Lutsar, I. (2014). Full-Length Genome Sequences of Estonian HIV-1 CRF06 and Eastern-European Subtype A1 Recombinant Forms. 7th National Congress HIV/AIDS and the 2nd Central European HIV Forum, Sibiu, Romania, 29-31 May 2014.
5.2.
2014
Pauskar, M.; Huik, K.; Avi, R.; Kallas, E.; Jõgeda, E.-L.; Karki, T.; Semjonova, S.; Smidt, J.; Novikova, L.; Ainsalu, K.; Lutsar, I. (2014). Antiretroviral drug resistance and viral tropism in HIV-1 CRF06_cpx infected patients failing antiretroviral (ARV) therapy. 7th National Congress HIV/AIDS and the 2nd Central European HIV Forum, Sibiu, Romania, 29-31 May 2014.
5.2.
2014
Kallas, E.; Huik, K.; Avi, R; Pauskar, M.; Jõgeda, E.-L.; Karki, T.; Marsh, K.; Des Jarlais, D.; Uusküla, A.; Lutsar, I. (2014). NLRP3 genotype CG increases the risk of HIV-1 in Caucasian intravenous drug users (IDUs). European Human Genetics Conference 2014, Milan, Italy, 31 May-3 June 2014.
5.2.
2014
Jõgeda, E.-L.; Huik, K.; Avi, R; Pauskar, M., Kallas, E.; Karki, T.; Marsh, K.; Des Jarlais, D.; Uusküla, A.; Lutsar, I. (2014). Associations between MX2 polymorphism and the acquisition of HIV and co-infections in Caucasian intravenous drug users (IDUs). European Human Genetics Conference 2014, Milan, Italy, 31 May-3 June 2014.
5.2.
2014
Kallas, E.; Avi, R.; Huik, K.; Türk, S.; Pauskar, M.; Jõgeda, E.-.L.; Šunina, M.; Des Jarlais, D.; Uusküla, A.; Lutsar, I. (2014). Injection drug use influences T-cell distribution and CCR5 expression in HIV+ and ESN population. 24th European Congress of Clinical Microbiology and Infectious Diseases; Barcelona; 10-13 May 2014.
1.1.
2013
Huik, K; Avi, R; Pauskar, M; Kallas, E; Jõgeda, EL; Karki, T; Marsh, K; Des Jarlais, D; Uusküla, A; Lutsar, I (2013). Association between TLR3 rs3775291 and resistance to HIV among highly exposed Caucasian intravenous drug users. Infection Genetics and Evolution, 20, 78−82.10.1016/j.meegid.2013.08.008.
1.1.
2013
Huik, K; Avi, R; Carrillo, A; Harper, N; Pauskar, M; Sadam, M; Karki, T; Krispin, T; He, W; Lutsar, I (2013). CCR5 Haplotypes Influence HCV Serostatus in Caucasian Intravenous Drug Users. PLoS ONE, 8 (7), e70561. DOI: 10.1371/journal.pone.0070561.
5.2.
2013
Avi, Radko; Huik, Kristi; Pauskar, Merit; Kallas, Eveli; Jõgeda, Ene-Ly; Karki, Tõnis; Šmidt, Jelena; Novikova, Lilia; Semjonova, Svetlana; Lutsar, Irja. (2013). Substitutions in RNaseH and Connection domain of HIV-1 CRF06_cpx viruses in treatment naive and treatment experienced populations. 11th European Meeting on HIV & Hepatitis- Treatment Strategies & Antiviral Drug Resistance; Rome; 20-22 March 2013. 35−35.
5.2.
2013
Kallas, Eveli; Huik, Kristi; Av1, Radko; Pauskar, Merit; Jõgeda, Ene-Ly; Karki, Tõnis; Marsh, Kristina; Des Jarlais, Don; Uusküla, Anneli; Lutsar, Irja (2013). The IL-10 promoter genotype AA at -592 is correlated with increased susceptibility to hepatitis B but not HIV infection in Caucasian intravenous drug users. European Human Genetics Conference 2013, Paris, France, 8.06.13-11.06.13.
5.2.
2013
Jõgeda, Ene-Ly; Huik, Kristi; Pauskar, Merit; Kallas, Eveli; Krispin, Tõnu; Karki, Tõnis; Marsh, Kristina; Des Jarlais, Don; Uusküla, Anneli; Avi, Radko; Lutsar, Irja. (2013). The prevalence of GBV-C and its associations with HIV infection among Estonian intravenous drug users. Reviews in Antiviral Therapy Infectious Diseases: 11th European Meeting on HIV & Hepatitis- Treatment Strategies & Antiviral Drug Resistance; Rome; 20-22 March 2013. 46−47.
5.2.
2013
Parm, Ü.; Metsvaht, T.; Ilmoja, ML.; Pauskar, M.; Lutsar, I. (2013). Associations between feeding regimen, mucosal colonization and prevalence of sepsis in neonates admitted to neonatal intensive care unit (NICU). ECCMID; European Congress on Clinical Microbiology and Infectious Diseases; Berlin, Germany; April 27-30, 2013.. Konverentsi kogumik, X−X.
1.1.
2012
Soeorg, H.; Tamm, E.; Huik, K.; Pauskar, M.; Mägi, D.; Pruudel, K.; Vainomäe, L.; Moosar, L.; Kirss, K.; Torm, S.; Närska, M.; Pütsepp, A.; Nurm, H.; Pruunsild, K.; Jänes, A.; Zilmer, K.; Lutsar, I. (2012). Group A rotavirus genotypes circulating prior to implementation of a National Immunization Program in Estonia. Human Vaccines, 8 (4), 465−469.10.4161/hv.19135.
5.2.
2012
Avi, R.; Huik, K.; Pauskar, M., Lutsar, I.; Vandamme, A.; Abecasis, A. (2012). The population dynamics of the HIV-1 epidemic in Estonia through virus genetic analysis and national case recording. 17th International BioInformatics Workshop on Virus Evolution and Molecular Epidemiology, 27-31 August 2012 Belgrade Serbia.
5.2.
2012
Pauskar, M.; Avi, R.; Huik, K.; Ustina, V.; Jõgeda, E.; Kallas, E.; Karki, T.; Krispin, T.; Lutsar, I. (2012). Transmitted drug resistance is 4.5% in newly diagnosed mainly HIV-1 CRF06_cpx infected patients in Estonia in 2010. 10th European Meeting on HIV & Hepatitis - Treatment Strategies & Antiviral Drug Resistance, 28 - 30 March 2012 Barcelona Spain.
5.2.
2012
Kallas, E.; Avi, R.; Huik, K.; Pauskar, M.; Ustina, V.; Karki, T.; Krispin, T.; Ainsalu, K.; Semjonova, S.; Kool, P.; Novikova, L.; Schmidt, J.; Lutsar, I. (2012). HIV Type-1 CRF06_cpx P(T/S)AP Late Domain duplications are outselected among treatment experienced compared to treatment naïve patients. Reviews in Antiviral Therapy & Infectious Diseases. ,.
5.2.
2012
Avi, R.; Huik, K.; Pauskar, M.; Kallas, E.; Karki, T.; Krispin, T.; Ainsalu, K.; Semjonova, S.; Kool, P.; Novikova, L.; Schmidt, J.; Lutsar, I. (2012). The pattern of drug resistance mutations in HIV-1 CRF06_cpx viruses failing the first-line NNRTI+2NRTI antiretroviral therapy. 10th European Meeting on HIV & Hepatitis - Treatment Strategies & Antiviral Drug Resistance, 28 - 30 March 2012 Barcelona Spain.
5.2.
2012
Uibopuu, H.; Huik, K.; Avi, R.; Pauskar, M.; Kallas, E.; Karki, T.; Krispin, T.; Kool, P.; Schmidt, J.; Rüütel, K.; Talu, A.; Abel-Ollo, K.; Uusküla, A.; Lutsar, I. (2012). Viral tropism of HIV-1 CRF06_cpx and its association with CCR5 haplotypes. 10th European Meeting on HIV & Hepatitis - Treatment Strategies & Antiviral Drug Resistance, 28 - 30 March 2012 Barcelona Spain.
5.2.
2012
Soeorg, Hiie; Huik, Kristi; Štšepetova, Jelena; Truusalu, Kai; Pauskar, Merit; Parm, Ülle; Ilmoja, Mari-Liis; Metsvaht, Tuuli; Lutsar, Irja (2012). Genetic relatedness of coagulase-negative staphylococci (CoNS) from gastrointestinal tract (GIT) and blood of neonates with late-onset sepsis (LOS). The 30th Annual Meeting of the European Society for Paediatric Infectious Diseases, May 8-12, 2012, Thessaloniki, Greece..
1.1.
2011
Avi, R; Huik, K; Pauskar, M; Ustina, V; Karki, T; Krispin, T; Ainsalu, K; Paap, P; Schmidt, J; Nikitina, N; Lutsar, I. (2011). Emerging Transmitted Drug Resistance in Treatment Naive Human Immunodeficiency Virus - 1 CRF06_cpx Infected Patients in Estonia. Scandinavian Journal of Infectious Diseases, 43 (2), 122−128.
1.1.
2011
Parm, U.; Metsvaht, T.; Sepp, E.; Ilmoja, ML.; Pisarev, H.; Pauskar, M.; Lutsar, I. (2011). Risk factors associated with gut and nasopharyngeal colonization by common Gram-negative species and yeasts in neonatal intensive unit patients. Early Human Development, 87 (6), 391−399.10.1016/j.earlhumdev.2011.02.007.
1.1.
2011
Parm, U.; Metsvaht, T.; Sepp, E.; Ilmoja, ML.; Pisarev, H.; Pauskar, M.; Lutsar, I. (2011). Mucosal surveillance cultures in predicting Gram-negative late-onset sepsis in neonatal intensive care units. Journal of Hospital Infection, 78 (4), 327−332.10.1016/j.jhin.2011.03.025.
5.2.
2011
Parm, U.; Metsvaht, T.; Sepp, E.; Ilmoja, ML.; Pisarev, H.; Pauskar, M.; Lutsar, I. (2011). Risk factors associated with gut and nasopharyngeal colonization by common Gram-negative species and yeasts in NICU. European Congress of Clinical Microbiology and Infectious Diseases, Milano, May 7-10, 2011..
1.1.
2010
Parm, Ü.; Metsvaht, T.; Sepp, E.; Ilmoja, ML.; Pisarev, H.; Pauskar, M.; Lutsar, I. (2010). Impact of empiric antibiotic regimen on bowel colonization in neonates with suspected early onset sepsis. European Journal of Clinical Microbiology & Infectious Diseases, 29 (7), 807−816.10.1007/s10096-010-0931-1.
5.2.
2010
Parm, Ülle; Sepp, Epp; Metsvaht, Tuuli; Ilmoja, Mari-Liis; Pruunsild, Kaie; Maipuu, Lea; Pauskar, Merit; Lutsar, Irja. (2010). Relevance of mucosal surveillance cultures in predicting Gram-negative sepsis in neonatal intensive care units (NICU). European Congress of Clinical Microbiology and Infectious Diseases, Vienna 2010..
5.2.
2010
Huik, Kristi; Parm, Ülle; Denks, Kärt; Pauskar, Merit; Lutsar, Irja. (2010). magA, k2A, rmpA and kfu genes are not related to onset neonatal sepsis of Klebsiella pneumoniae in neonatal intensive care units in two major hospitals in Estonia. European Congress of Clinical Microbiology and Infectious Diseases, Vienna 2010..
3.5.
2009
Parm, Ülle; Metsvaht, Tuuli; Sepp, Epp; Pisarev, Heti; Ilmoja, Mari-Liis; Pauskar, Merit; Lutsar, Irja (2009). Impact of empiric antibiotic regimen on bowel colonization in neonates with suspected early onset sepsis. Posterettekanne 16-19 mail 2009 Helsingis (19th ECCMID).
5.2.
2009
Pauskar, M.; Parm, Ü.; Sepp, E.; Metsvaht, T. ; Ilmoja, M.-L.; Lutsar, I. (2009). Gut colonization by Staphylococci in neonates with suspected early onset sepsis influenced by empiric antibiotic therapy. Well-known infections the hottest features of diagnostics and treatment: VIII Nordic-Baltic congress of infectious Diseases; Saint Petersburg, Russia; 23.-26.09.2009. 60.
3.5.
2008
• Parm, Ü; Sepp, E; Metsvaht, T; Ilmoja, M.-L.; Pauskar, M; Kilg, T; Mihhailova, M; Lutsar, I. (2008). Ampitsilliini ja penitsilliini mõju kolonisatsiooni tekkele oportunistlike mikroobidega. Eesti Arst: TÜ Arstiteaduskonna päevadel 9 okt 2008.
13.02.2021

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ETFETF8415CCR5 ja CCL3L1 geneetiliste polümorfismide ning nende ekspressiooni mõjutavate viiruste mõju immuunaktivatsioonile antiretroviirusliku ravi foonil HIV-positiivsetel isikutel01.01.201031.12.2013Tõnis KarkiTartu Ülikool, Arstiteaduskond61 354,00 EUR
IUTIUT34-24Infektsioonid langenud immuunsusega isikutel – eksperimendist kliinilisse praktikasse01.01.201531.12.2020Irja LutsarTartu Ülikool, Meditsiiniteaduste valdkond, bio- ja siirdemeditsiini instituut698 400,00 EUR