Pille Pata

https://www.etis.ee/CV/Pille_Pata/est
14.07.1981
+3726204433
+37256638266
pille.pata@ttu.ee

Teenistuskäik

Töökohad ja ametid
01.05.2019–...   
Tallinna Tehnikaülikool, Loodusteaduskond, Keemia ja biotehnoloogia instituut, insener (0,50)
01.01.2017–30.04.2019   
Tallinna Tehnikaülikool, Loodusteaduskond, Keemia ja biotehnoloogia instituut, insener (1,00)
01.12.2015–31.12.2016   
Tallinna Tehnikaülikool, Matemaatika-loodusteaduskond, Keemiainstituut, Rohelise keemia õppetool, insener (1,00)
01.01.2009–30.06.2009   
Vähiuuringute Tehnoloogia Arenduskeskus AS, Teadur (0,50)
2007–31.12.2016   
Tallinna Tehnikaülikool, Matemaatika-loodusteaduskond, Geenitehnoloogia instituut, insener (0,10)
01.06.2004–31.12.2005   
Keemilise ja Bioloogilise Füüsika Instituut, insener (1,00)
01.09.2003–30.04.2004   
Columbia University (New York), külalisteadur (1,00)
 
 
Haridustee
2004–2008   
magistrantuur (teadus), Tallinna Tehnikaülikool, geenitehnoloogia
1999–2003   
B. Sc., Tartu Ülikool, geenitehnoloogia

Kvalifikatsioon

Teaduskraadid
Pille Pata, magistrikraad (teaduskraad), 2008, (juh) Priit Kogerman; Illar Pata, Gli transkriptsioonifaktorid Hedgehog/Wnt interaktsioonide vahendajatena, Tallinna Tehnikaülikool, Matemaatika-loodusteaduskond, Geenitehnoloogia instituut.
Pille Pata, doktorant, (juh) Illar Pata, Hh and Wnt interactions in tumor biology (Hh ja Wnt signaaliradade interaktsioonid kasvajate bioloogias), Tallinna Tehnikaülikool, Matemaatika-loodusteaduskond, Geenitehnoloogia instituut, Molekulaardiagnostika õppetool.
 
 
Teadustöö põhisuunad
ETIS KLASSIFIKAATOR: 1. Bio- ja keskkonnateadused; 1.12. Bio- ja keskkonnateadustega seotud uuringud, näiteks biotehnoloogia, molekulaarbioloogia, rakubioloogia, biofüüsika, majandus- ja tehnoloogiauuringud; TÄPSUSTUS: kasvajate molekulaarbioloogia
 
 
Lisainfo
Olen olnud lapsehoolduspuhkusel ajavahemikus sept. 2005 - okt. 2007.

Lõppenud projektid

Juhendamisel väitekirjad

Juhendatud väitekirjad

Publikatsioonid

Klass
Aasta
Publikatsioon
 
1.1.
2019
Teras, J.; Kroon, H. M.; Thompson, J. F.; Teras, M.; Pata, P.; Mägi, A.; Teras, R. M.; Rüütel Boudinot, S. (2019). First Eastern European Experience of Isolated Limb Infusion for In-Transit Metastatic Melanoma Confined to the Limb: Is it still an Effective Treatment Option in the Modern Era? European Journal of Surgical Oncology.10.1016/j.ejso.2019.10039 [ilmumas].
1.1.
2018
Kovacovicova, K.; Skolnaja, M.; Heinmaa, M.; Mistrik, M.; Pata, P.; Pata, I.; Bartek, J.; Vinciguerra, M. (2018). Senolytic Cocktail Dasatinib+Quercetin (D+Q) Does Not Enhance the Efficacy of Senescence-Inducing Chemotherapy in Liver Cancer. Frontiers in Oncology.10.3389/fonc.2018.00459.
1.1.
2018
Teras, Marina; Viisileht, Edda; Pahtma-Hall, Merlis; Rump, Airi; Paalme, Viiu; Pata, Pille; Pata, Illar; Langevin, Christelle; Boudinot, Sirje Ruutel (2018). Porcine circovirus type 2 ORF3 protein induces apoptosis in melanoma cells. BMC Cancer, 18, ARTN 1237.10.1186/s12885-018-5090-2.
5.2.
2018
Silm, E.; Pata, P.; Kruis, J. C.; Sikerina, A.; Pata, I.; Kanger, T.; Gathergood, N. (2018). Catalysts derived from sustainable natural and value added alkaloids from poppies. IUPAC Postgraduate Summer School on Green Chemistry 7-14 July 2018 Venice, Italy. IUPAC , 24.
5.2.
2018
Silm, E.; Pata,P.; Kruis, J. C.; Sikerina, A.; Pata, I.; Kanger, T.; Gathergood, N. (2018). Catalysts derived from sustainable natural and value added alkaloids from poppies. 3rd Green and Sustainable Chemistry Conference, Berlin, 13-16th May 2018. Elsevier, p1.29.
5.2.
2017
Silm, E.; Pata, P.; Kruis, J. C.; Sikerina, A.; Pata, I.; Kanger, T.; Gathergood, N. (2017). Catalysts derived from sustainable natural and value added alkaloids from poppies. 20th European Symposium on Organic Chemistry 2-6 July 2017 Cologne, Germany. Universität zu Köln,.
1.1.
2016
Toompuu, M.; Kärblane, K.; Pata, P.; Truve, E.; Sarmiento, C. (2016). ABCE1 is essential for S phase progression in human cells. Cell Cycle, 1.10.1080/15384101.2016.1160972.
1.1.
2016
Jueliger, S.; Lyons, J.; Cannito, S.; Pata, I.; Pata, P.; Shkolnaya, M.; Lo Re, O.; Peyrou, M.; Villarroya, F.; Pazienza, V.; Rappa, F.; Cappello, F.; Azab, M.; Taverna, P.; Vinciguerra, M. (2016). Efficacy and epigenetic interactions of novel DNA hypomethylating agent guadecitabine (SGI-110) in preclinical models of hepatocellular carcinoma. Epigenetics, 00−00.10.1080/15592294.2016.1214781.
1.1.
2016
Jueliger, Simone; Lyons, John; Cannito, Sara; Pata, Illar; Pata, Pille; Shkolnaya, Marianna; Lo Re, Oriana; Peyrou, Marion; Villarroya, Francesc; Pazienza, Valerio; Rappa, Francesca; Cappello, Francesco; Azab, Mohammad; Taverna, Pietro; Vinciguerra, Manlio (2016). Efficacy and epigenetic interactions of novel DNA hypomethylating agent guadecitabine (SGI-110) in preclinical models of hepatocellular carcinoma. Epigenetics, 11 (10), 709−720.15592294.2016.1214781.
1.1.
2015
Luker, K. E.; Pata, P.; Shemiakina, I. I.; Pereverzeva, A.; Stacer, A. C.; Shcherbo, D. S.; Pletnev, V. Z.; Skolnaja, M.; Lukyanov, K. A.; Luker, G. D.; Pata, I.; Chudakov, D. M. (2015). Comparative study reveals better far-red fluorescent protein for whole body imaging. Scientific Reports, 5, 10332.10.1038/srep10332.
5.2.
2015
Ojangu, E.-L.; Tanner, K.; Pata, P.; Järve, K.; Talts, K.; Truve, E.; Paves, H. (2015). Myosins XI-K, XI-1, and XI-2 are required for development of pavement cells, trichomes, and stigmatic papillae in Arabidopsis. Environmental Adaptation: from Molecules to the Planet. THe Estonian Centre of Excellence in Environmental Adaptation ENVIRON. Final Conference. Abstract Book. _EditorsAbbr Ostonen, I., Kurvits, T. Eesti Maaülikool, 49−50.
1.1.
2012
Ojangu, E.-L.; Tanner, K.; Pata, P.; Järve, K.; Holweg, C. L; Truve, E.; Paves, H. (2012). Myosins XI-K, XI-1, and XI-2 are required for development of pavement cells, trichomes, and stigmatic papillae in Arabidopsis. BMC Plant Biology, 12, 81.10.1186/1471-2229-12-81.
5.2.
2010
K. Kärblane, P. Pata, I. Pata, E. Truve and C. Sarmiento (2010). RNA silencing suppressors of plant viral and endogenous origin expressed in mammalian cells. Keystone Symposia "RNA silencing Mechanisms in Plants"; M. A. Matzke and J. C. Carrington; Feb 21-26, 2010; Santa Fe, New Mexico, USA. 87.
1.1.
2005
Shakya, Reena; Jho, Eek-hoon; Kotka, Pille; Wu, Zaigi; Kholodilov, Nikolai; Burke, Robert; D'Agati, Vivette; Costantini, Frank (2005). The role of GDNF in patterning the excretory system. Developmental Biology, 283 (1), 70−84.10.1016/j.ydbio.2005.04.008.
1.1.
2005
Wong, Adrianne; Bogni, Silvia; Kotka, Pille; Graaff, Esther de; D'Agati, Vivette; Costantini, Frank; Pachnis, Vassilis (2005). Phosphotyrosine 1062 is critical for the in vivo activity of the Ret9 receptor tyrosine kinase isoform. Molecular and Cellular Biology, 25 (21), 9661−9673.10.1128/MCB.25.21.9661-9673.2005.
1.1.
2002
Laht, Silja; Karp, Helen; Kotka, Pille; Järviste, Aiki; Alamäe, Tiina (2002). Cloning and characterization of glucokinase from a methylotrophic yeast Hansenula polymorpha: different effects on glucose repression in H-polymorpha and Saccharomyces cerevisiae. Gene, 296, 195−203.10.1016/S0378-1119(02)00859-4.

Tööstusomand

4.12.2019

Pille Pata

https://www.etis.ee/CV/Pille_Pata/eng
14.07.1981
+3726204433
+37256638266
pille.pata@ttu.ee

Career

Institutions and positions
01.05.2019–...   
Tallinn University of Technology , School of Science, Department of Chemistry and Biotechnology, Engineer (0,50)
01.01.2017–30.04.2019   
Tallinn University of Technology , School of Science, Department of Chemistry and Biotechnology, engineer (1,00)
01.12.2015–31.12.2016   
Tallinn University of Technology , Faculty of Science, Department of Chemistry, ERA Chair of Green Chemistry, engineer (1,00)
01.01.2009–30.06.2009   
Competence Center for Cancer Research, Researcher (0,50)
2007–31.12.2016   
Tallinn University of Technology , Faculty of Science, Department of Gene Technology, engineer (0,10)
01.06.2004–31.12.2005   
Keemilise ja Bioloogilise Füüsika Instituut, National Institute of Chemical Physics and Biophysics, engineer (1,00)
01.09.2003–30.04.2004   
Columbia University (New York), visiting researcher (1,00)
 
 
Education
2004–2008   
M.Sc. studies, Tallinn University of Technology, gene technology
1999–2003   
B. Sc., University of Tartu, gene technology

Qualifications

Academic degrees
Pille Pata, Research Master's Degree, 2008, (sup) Priit Kogerman; Illar Pata, Gli transkriptsioonifaktorid Hedgehog/Wnt interaktsioonide vahendajatena (Gli transcription factors as mediators of Hedgehog/Wnt interactions), Tallinn University of Technology Faculty of Science, Department of Gene Technology.
Pille Pata, Phd student, (sup) Illar Pata, Hh and Wnt interactions in tumor biology, Tallinn University of Technology Faculty of Science, Department of Gene Technology, Chair of Molecular Diagnostics.
 
 
Fields of research
ETIS CLASSIFICATION: 1. Biosciences and Environment; 1.12. Biotechnology, Molecular Biology, Cell Biology, Biophysics and Economic and Technological Research relating to Bio- and Environmental Sciences; SPECIFICATION: molecular biology of cancer
 
 
Additional information
I was at the maternity leave during Sept 2005 - Oct 2007.

Completed projects

Dissertations under supervision

Supervised dissertations

Publications

Category
Year
Publication
 
1.1.
2019
Teras, J.; Kroon, H. M.; Thompson, J. F.; Teras, M.; Pata, P.; Mägi, A.; Teras, R. M.; Rüütel Boudinot, S. (2019). First Eastern European Experience of Isolated Limb Infusion for In-Transit Metastatic Melanoma Confined to the Limb: Is it still an Effective Treatment Option in the Modern Era? European Journal of Surgical Oncology.10.1016/j.ejso.2019.10039 [forthcoming].
1.1.
2018
Kovacovicova, K.; Skolnaja, M.; Heinmaa, M.; Mistrik, M.; Pata, P.; Pata, I.; Bartek, J.; Vinciguerra, M. (2018). Senolytic Cocktail Dasatinib+Quercetin (D+Q) Does Not Enhance the Efficacy of Senescence-Inducing Chemotherapy in Liver Cancer. Frontiers in Oncology.10.3389/fonc.2018.00459.
1.1.
2018
Teras, Marina; Viisileht, Edda; Pahtma-Hall, Merlis; Rump, Airi; Paalme, Viiu; Pata, Pille; Pata, Illar; Langevin, Christelle; Boudinot, Sirje Ruutel (2018). Porcine circovirus type 2 ORF3 protein induces apoptosis in melanoma cells. BMC Cancer, 18, ARTN 1237.10.1186/s12885-018-5090-2.
5.2.
2018
Silm, E.; Pata, P.; Kruis, J. C.; Sikerina, A.; Pata, I.; Kanger, T.; Gathergood, N. (2018). Catalysts derived from sustainable natural and value added alkaloids from poppies. IUPAC Postgraduate Summer School on Green Chemistry 7-14 July 2018 Venice, Italy. IUPAC , 24.
5.2.
2018
Silm, E.; Pata,P.; Kruis, J. C.; Sikerina, A.; Pata, I.; Kanger, T.; Gathergood, N. (2018). Catalysts derived from sustainable natural and value added alkaloids from poppies. 3rd Green and Sustainable Chemistry Conference, Berlin, 13-16th May 2018. Elsevier, p1.29.
5.2.
2017
Silm, E.; Pata, P.; Kruis, J. C.; Sikerina, A.; Pata, I.; Kanger, T.; Gathergood, N. (2017). Catalysts derived from sustainable natural and value added alkaloids from poppies. 20th European Symposium on Organic Chemistry 2-6 July 2017 Cologne, Germany. Universität zu Köln,.
1.1.
2016
Toompuu, M.; Kärblane, K.; Pata, P.; Truve, E.; Sarmiento, C. (2016). ABCE1 is essential for S phase progression in human cells. Cell Cycle, 1.10.1080/15384101.2016.1160972.
1.1.
2016
Jueliger, S.; Lyons, J.; Cannito, S.; Pata, I.; Pata, P.; Shkolnaya, M.; Lo Re, O.; Peyrou, M.; Villarroya, F.; Pazienza, V.; Rappa, F.; Cappello, F.; Azab, M.; Taverna, P.; Vinciguerra, M. (2016). Efficacy and epigenetic interactions of novel DNA hypomethylating agent guadecitabine (SGI-110) in preclinical models of hepatocellular carcinoma. Epigenetics, 00−00.10.1080/15592294.2016.1214781.
1.1.
2016
Jueliger, Simone; Lyons, John; Cannito, Sara; Pata, Illar; Pata, Pille; Shkolnaya, Marianna; Lo Re, Oriana; Peyrou, Marion; Villarroya, Francesc; Pazienza, Valerio; Rappa, Francesca; Cappello, Francesco; Azab, Mohammad; Taverna, Pietro; Vinciguerra, Manlio (2016). Efficacy and epigenetic interactions of novel DNA hypomethylating agent guadecitabine (SGI-110) in preclinical models of hepatocellular carcinoma. Epigenetics, 11 (10), 709−720.15592294.2016.1214781.
1.1.
2015
Luker, K. E.; Pata, P.; Shemiakina, I. I.; Pereverzeva, A.; Stacer, A. C.; Shcherbo, D. S.; Pletnev, V. Z.; Skolnaja, M.; Lukyanov, K. A.; Luker, G. D.; Pata, I.; Chudakov, D. M. (2015). Comparative study reveals better far-red fluorescent protein for whole body imaging. Scientific Reports, 5, 10332.10.1038/srep10332.
5.2.
2015
Ojangu, E.-L.; Tanner, K.; Pata, P.; Järve, K.; Talts, K.; Truve, E.; Paves, H. (2015). Myosins XI-K, XI-1, and XI-2 are required for development of pavement cells, trichomes, and stigmatic papillae in Arabidopsis. Environmental Adaptation: from Molecules to the Planet. THe Estonian Centre of Excellence in Environmental Adaptation ENVIRON. Final Conference. Abstract Book. _EditorsAbbr Ostonen, I., Kurvits, T. Eesti Maaülikool, 49−50.
1.1.
2012
Ojangu, E.-L.; Tanner, K.; Pata, P.; Järve, K.; Holweg, C. L; Truve, E.; Paves, H. (2012). Myosins XI-K, XI-1, and XI-2 are required for development of pavement cells, trichomes, and stigmatic papillae in Arabidopsis. BMC Plant Biology, 12, 81.10.1186/1471-2229-12-81.
5.2.
2010
K. Kärblane, P. Pata, I. Pata, E. Truve and C. Sarmiento (2010). RNA silencing suppressors of plant viral and endogenous origin expressed in mammalian cells. Keystone Symposia "RNA silencing Mechanisms in Plants"; M. A. Matzke and J. C. Carrington; Feb 21-26, 2010; Santa Fe, New Mexico, USA. 87.
1.1.
2005
Shakya, Reena; Jho, Eek-hoon; Kotka, Pille; Wu, Zaigi; Kholodilov, Nikolai; Burke, Robert; D'Agati, Vivette; Costantini, Frank (2005). The role of GDNF in patterning the excretory system. Developmental Biology, 283 (1), 70−84.10.1016/j.ydbio.2005.04.008.
1.1.
2005
Wong, Adrianne; Bogni, Silvia; Kotka, Pille; Graaff, Esther de; D'Agati, Vivette; Costantini, Frank; Pachnis, Vassilis (2005). Phosphotyrosine 1062 is critical for the in vivo activity of the Ret9 receptor tyrosine kinase isoform. Molecular and Cellular Biology, 25 (21), 9661−9673.10.1128/MCB.25.21.9661-9673.2005.
1.1.
2002
Laht, Silja; Karp, Helen; Kotka, Pille; Järviste, Aiki; Alamäe, Tiina (2002). Cloning and characterization of glucokinase from a methylotrophic yeast Hansenula polymorpha: different effects on glucose repression in H-polymorpha and Saccharomyces cerevisiae. Gene, 296, 195−203.10.1016/S0378-1119(02)00859-4.

Industrial property

4.12.2019
Detailne otsing
  • Leitud 4 kirjet
ProgrammLiikNumberNimiProjekti algusProjekti lõppVastutav täitjaAsutusFinantseerijapoolne rahastamine
1.2.3.3.VFP655Excellent Tallinn University of Technology Research Chair in Green Chemistry and Technology01.05.201430.04.2019Nicholas GathergoodTallinna Tehnikaülikool2 285 081,75 EUR
ETFETF6139Hedgehogi signaaliraja aktiivsuse moduleerimine in vivo: selle võimalused kasvajate ravis01.01.200531.12.2008Illar PataTallinna Tehnikaülikool, Matemaatika-loodusteaduskond26 270,25 EUR
MUUBF59In vivo bioluminestsents-kuvamise mudelite arendamine vähiteraapia mõju hindamiseks01.01.200731.12.2008Illar PataTallinna Tehnikaülikool; Tallinna Tehnikaülikool, Matemaatika-loodusteaduskond, Geenitehnoloogia instituut15 977,91 EUR
SFSF0140145As08Tuumorprogressiooni molekulaarbioloogia: molekulaarsed mehhanismid ja biomeditsiinilised rakendused01.01.200831.12.2013Andres ValknaTallinna Tehnikaülikool, Matemaatika-loodusteaduskond616 089,84 EUR