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Olen nõus

Pille Hallast

https://www.etis.ee/CV/Pille_Hallast/est
12.07.1980
737 5009
pille.hallast@ut.ee

Teenistuskäik

Töökohad ja ametid
11.10.2017–...   
Tartu Ülikool, Meditsiiniteaduste valdkond, bio- ja siirdemeditsiini instituut, inimese molekulaargeneetika vanemteadur (1,00)
15.08.2017–...   
Tartu Ülikool, Meditsiiniteaduste valdkond, bio- ja siirdemeditsiini instituut, inimese geneetika vanemteadur (1,00)
01.02.2016–...   
The Wellcome Trust Sanger Institute, Külalisteadur (0,01)
01.01.2016–15.08.2017   
Tartu Ülikool, Bioloogia-geograafiateaduskond, Molekulaar- ja rakubioloogia instituut, inimese molekulaargeneetika vanemteadur (1,00)
01.09.2015–31.12.2015   
Tartu Ülikool, Loodus- ja tehnoloogiateaduskond, Tartu Ülikooli Molekulaar- ja Rakubioloogia Instituut, inimese molekulaargeneetika vanemteadur (1,00)
01.01.2010–31.07.2015   
Leicesteri Ülikool, järeldoktorantuur (1,00)
01.11.2009–31.10.2012   
Tartu Ülikool, Loodus- ja tehnoloogiateaduskond, Tartu Ülikooli Molekulaar- ja Rakubioloogia Instituut, inimese molekulaargeneetika teadur (1,00)
01.09.2008–31.10.2009   
Tartu Ülikool, Loodus- ja tehnoloogiateaduskond, Tartu Ülikooli Molekulaar- ja Rakubioloogia Instituut, teadur (1,00)
01.09.2008–31.12.2008   
Eesti Biokeskus, Spetsialist (EL 6. raamprojekti “PROUST” administraator) (0,25)
31.05.2007–31.08.2008   
Eesti Biokeskus, Spetsialist (EL 6. raamprojekti “PROUST” administraator) (0,50)
01.05.2007–31.05.2007   
Tartu Ülikool, Bioloogia-geograafiateaduskond, Molekulaar- ja rakubioloogia instituut, spetsialist (0,25)
01.01.2007–31.12.2008   
Eesti Biokeskus, spetsialist (EL 6. raamprojekti “PROUST” administraator)(0.5)
2004–2004   
Tartu Ülikool, Bioloogia-geograafiateaduskond, Molekulaar- ja rakubioloogia instituut, vanemlaborant (1,00)
2004–2009   
Tartu Ülikool, Bioloogia-geograafiateaduskond, Molekulaar- ja rakubioloogia instituut, doktorant (1,00)
01.01.2002–31.12.2005   
AS Asper Biotech, genotüpiseerimise projektijuht
01.01.2000–31.12.2002   
AS Asper Biotech, laborant
 
 
Haridustee
2006–2006   
Külalisteadlane, Soome Genoomikeskuses, Helsingi Biomeedikum, Helsingi Ülikool, Soome
2004–2009   
Tartu Ülikool, geenitehnoloogia eriala, Ph.D õpingud
2002–2004   
Tartu Ülikool, geenitehnoloogia eriala, M.Sc
1998–2002   
Tartu Ülikool, geenitehnoloogia eriala, B.Sc
1995–1998   
Hugo Treffneri Gümnaasium
 
 
Teadusorganisatsiooniline ja -administratiivne tegevus
2004−...   
Eesti Biokeemia Seltsi liige
1999−...   
Eesti Inimesegeneetika Ühingu liige
1999−...   
Üliõpilaskorporatsiooni Filiae Patriae liige
2008−2008   
Rahvusvahelise in silico praktilise kursuse “Temporal aspects in genetic analysis” (Tartu, Eesti) korraldamine EL 6. raamprojekti “PROUST – The temporal dimension in functional genomics” raames
2008−2008   
Osalemine konverentsi “Genes at work on time” (Toriino, Itaalia) korraldamises EL 6. raamprojekti “PROUST – The temporal dimension in functional genomics” raames

Kvalifikatsioon

Teaduskraadid
Pille Hallast, doktorikraad, 2009, (juh) Maris Laan, Human and chimpanzee Luteinizing Hormone/ Chorionic Gonadotropin Beta (LHB/CGB) gene clusters: diversity and divergence of young duplicated genes, Tartu Ülikool, Loodus- ja tehnoloogiateaduskond, Tartu Ülikooli Molekulaar- ja Rakubioloogia Instituut.
Pille Hallast, magistrikraad (teaduskraad), 2004, (juh) Maris Laan, Geenikonversiooni roll lokaalsete alleelse aheldatuse (LD) mustrite kujundamises inimese genoomis kooriongonadotropiini beta subühiku (CGB) geeniperekonna näitel, Tartu Ülikool, Bioloogia-geograafiateaduskond.
 
 
Teaduspreemiad ja tunnustused
2009, Pille Hallast, Kristjan Jaagu stipendium osavõtuks kursusest Wellcome Trust Advanced Courses “Molecular Evolution” (Hinxton, UK)
2009, Pille Hallast, Eesti Haridus ja Teadusministeeriumi Üliõpilaste teadustööde konkursi peapreemia doktoritööde kategoorias
2008, Pille Hallast, Parima postri preemia konverentsil “The 2nd International Conference on Gonadotrophins and Their Receptors” (Hertfordshire, UK)
2007, Pille Hallast, Harald Raudsepa nimeline stipendium, Estonian-Revelia Academic Fund
2007, Pille Hallast, Estonian Students Fund (USA) stipendium
2007, Pille Hallast, Biotehnoloogia ja biomeditsiini doktorikooli toetus osalemaks konverentsil “The Biology of Genomes” (Cold Spring Harbor, USA)
2007, Pille Hallast, Kristjan Jaagu stipendium osavõtuks konverentsil “The 9th International Meeting on Human Genome Variation and Complex Genome Analysis" (Barcelona, Hispaania)
2006, Pille Hallast, Bilateraalne vahetusüliõpilaste programmi stipendium üheks semestriks Helsingi Ülikoolis, Soomes
2006, Pille Hallast, Biotehnoloogia ja biomeditsiini doktorikooli toetus osalemaks konverentsil "HUGO (The Human Genome Organisation) 11th International Genome Meeting" (Helsingi, Soome)
2006, Pille Hallast, Eesti Haridus- ja Teadusministeeriumi Kristjan Jaaku Osalise Õppe Stipendium
2005, Pille Hallast, Maailma Teadlaste Föderatsiooni stipendium 1 aastaks
2005, Pille Hallast, Korralduskomitee stipendium konverentsil “International Conference on Gonadotropins and Receptors” (Athens, USA) osalemiseks
2004, Pille Hallast, Kristjan Jaagu stipendium osavõtuks konverentsil “Human Genome Meeting 2004” (Berliin, Saksamaa)
2003, Pille Hallast, Artur Linnu stipendium
2003, Pille Hallast, Harald Raudsepa nimeline stipendium, Estonian-Revelia Academic Fund
2002, Pille Hallast, Diplom Eesti Haridus ja teadusministeeriumi Üliõpilaste teadustööde konkursil bakalaureuse astmes
 
 
Teadustöö põhisuunad
VALDKOND: 1. Bio- ja keskkonnateadused; 1.3. Geneetika

Jooksvad projektid

Lõppenud projektid

Juhendamisel väitekirjad

Publikatsioonid

Klass
Aasta
Publikatsioon
 
1.1.
2018
Shi, Wentao; Massaia, Andrea; Louzada, Sandra; Banerjee, Ruby; Hallast, Pille; Chen, Yuan; Bergström, Anders; Gu, Yong; Leonard, Steven; Quail, Michael A; Ayub, Qasim; Yang, Fengtang; Tyler-Smith, Chris; Xue, Yali (2018). Copy number variation arising from gene conversion on the human Y chromosome. Human Genetics, 137 (1), 73−83.10.1007/s00439-017-1857-9.
1.1.
2017
Maisano Delser, P.; Neumann, R.; Ballereau, S.; Hallast, P.; Batini, C.; Zadik, D.; Jobling, MA. (2017). Signatures of human European Palaeolithic expansion shown by resequencing of non-recombining X-chromosome segments. European Journal of Human Genetics, 25 (4), 485−492.10.1038/ejhg.2016.207.
1.1.
2017
Hallast, Pille; Jobling, Mark A. (2017). The Y chromosomes of the great apes. Human Genetics, 136 (5, 5), 511−528.10.1007/s00439-017-1769-8.
1.1.
2017
Batini, Chiara; Hallast, Pille; Vågene, Åshild J; Zadik, Daniel; Eriksen, Heidi A; Pamjav, Horolma; Sajantila, Antti; Wetton, Jon H; Jobling, Mark A (2017). Population resequencing of European mitochondrial genomes highlights sex-bias in Bronze Age demographic expansions. Scientific Reports, 7 (1), 12086−12086.10.1038/s41598-017-11307-9.
1.1.
2016
Hallast, Pille; Maisano Delser, Pierpaolo; Batini, Chiara; Zadik, Daniel; Rocchi, Mariano; Schempp, Werner; Tyler-Smith, Chris; Jobling, Mark A (2016). Great ape Y Chromosome and mitochondrial DNA phylogenies reflect subspecies structure and patterns of mating and dispersal. Genome Research, 26 (4), 427−439.10.1101/gr.198754.115.
1.1.
2016
de Manuel, Marc; Kuhlwilm, Martin; Frandsen, Peter; Sousa, Vitor C; Desai, Tariq; Prado-Martinez, Javier; Hernandez-Rodriguez, Jessica; Dupanloup, Isabelle; Lao, Oscar; Hallast, Pille; Schmidt, Joshua M; Heredia-Genestar, José María; Benazzo, Andrea; Barbujani, Guido; Peter, Benjamin M; Kuderna, Lukas F K; Casals, Ferran; Angedakin, Samuel; Arandjelovic, Mimi; Boesch, Christophe ... Marques-Bonet, Tomas (2016). Chimpanzee genomic diversity reveals ancient admixture with bonobos. Science (New York, N.Y.), 354 (6311), 477−481.10.1126/science.aag2602.
1.1.
2016
Haber, Marc; Mezzavilla, Massimo; Bergström, Anders; Prado-Martinez, Javier; Hallast, Pille; Saif-Ali, Riyadh; Al-Habori, Molham; Dedoussis, George; Zeggini, Eleftheria; Blue-Smith, Jason; Wells, R Spencer; Xue, Yali; Zalloua, Pierre A; Tyler-Smith, Chris (2016). Chad Genetic Diversity Reveals an African History Marked by Multiple Holocene Eurasian Migrations. American Journal of Human Genetics, 99 (6), 1316−1324.10.1016/j.ajhg.2016.10.012.
1.1.
2015
Batini, Chiara; Hallast, Pille; Zadik, Daniel; Maisano Delser, Pierpaolo; Benazzo, Andrea; Ghirotto, Silvia; Arroyo-Pardo, Eduardo; Cavalleri, Gianpiero L.; de Knijff, Peter; Dupuy, Berit Myhre; Eriksen, Heidi A.; King, Turi E.; López de Munain, Adolfo; López-Parra, Ana M.; Loutradis, Aphrodite; Milasin, Jelena; Novelletto, Andrea; Pamjav, Horolma; Sajantila, Antti; Tolun, Aslıhan ... Jobling, Mark A. (2015). Large-scale recent expansion of European patrilineages shown by population resequencing. Nature Communications, 6 (7152), x−x.10.1038/ncomms8152.
1.1.
2015
Hallast, Pille; Batini, Chiara; Zadik, Daniel; Maisano Delser, Pierpaolo; Wetton, Jon H.; Arroyo-Pardo, Eduardo; Cavalleri, Gianpiero L.; de Knijff, Peter; Destro Bisol, Giovanni; Myhre Dupuy, Berit; Eriksen, Heidi A.; Jorde, Lynn B.; King, Turi E.; Larmuseau, Maarten H.; López de Munain, Adolfo; López-Parra, Ana M.; Loutradis, Aphrodite; Milasin, Jelena; Novelletto, Andrea; Pamjav, Horolma ... Jobling, Mark A. (2015). The Y-Chromosome Tree Bursts into Leaf: 13,000 High-Confidence SNPs Covering the Majority of Known Clades. Molecular Biology and Evolution, 32 (3), 661−673.10.1093/molbev/msu327.
5.2.
2015
Hallast, Pille; Maisano Delser, Pierpaolo; Batini, Chiara; Zadik, Daniel; Schempp, Werner; Rocchi, Mariano; Tyler-Smith, Chris; Jobling, Mark A. (2015). Great ape Y chromosome diversity reflects sub-species structure and sex-biased behaviours. Abstract book: The Biology of Genomes, Cold Spring Harbor, NY, USA, 05.05-09.05.2015; Society of Molecular Biology & Evolution (SMBE), Vienna, Austria, 12.-16. juuni 2015.
5.2.
2015
Batini, Chiara; Hallast, Pille; Zadik, Daniel; Maisano Delser, Pierpaolo; Benazzo, Andrea; Ghirotto, Silvia; Arroyo-Pardo, Eduardo; Cavalleri, Gianpiero L.; de Knijff, Peter; Dupuy, Berit Myhre; Eriksen, Heidi A.; King, Turi E.; López de Munain, Adolfo; López-Parra, Ana M.; Loutradis, Aphrodite; Milasin, Jelena; Novelletto, Andrea; Pamjav, Horolma; Sajantila, Antti; Tolun, Aslıhan ... Jobling, Mark A. (2015). Contrasting patterns in the high-resolution variation of uniparental markers in European populations highlight very recent male-specific expansions. Abstract books: The Biology of Genomes, Cold Spring Harbor, NY, USA, 05.05-09.05.2015; Society of Molecular Biology & Evolution (SMBE), Vienna, Austria, 12.-16. juuni 2015.
5.2.
2014
Batini, C.; Hallast, P.; Zadik, D.; Maisano Delser, P.; Wetton, JH.; Arroyo, E.; Bodmer, W.; Cavalleri, G.; de Knijff, P.; Destro Bisol, G.; Jobling, MA. (2014). Insights into the peopling of Europe through a high‐confidence Y‐chromosome phylogeny. Conference abstract book; abstract no 58: EMBO conference "Human evolution in the genomic era: Origins, populations and phenotypes", 1 – 4 April 2014, Leicester, UK.
5.2.
2014
Zadik, D.; Batini, C.; Hallast, P.; Maisano Delser, P.; Jobling, MA. (2014). Using cross‐species sequence‐capture and next‐generation sequencing to assess the role of gene conversion in the evolution of the human sex chromosomes. Conference abstract book; abstract no 76: EMBO conference "Human evolution in the genomic era: Origins, populations and phenotypes", 1 – 4 April 2014, Leicester, UK.
5.2.
2014
Maisano Delser, P.; Neumann, R.; Hallast, P.; Batini, C.; Lall, G.; Patel, S.; Zadik, D.; Ballereau, S.; Jobling, MA. (2014). Excavating European demographic history using NGS of X‐chromosomal haplotype blocks. Conference abstract book; abstract no 80: EMBO conference "Human evolution in the genomic era: Origins, populations and phenotypes", 1 – 4 April 2014, Leicester, UK.
1.1.
2013
Hallast, Pille; Balaresque, Patricia; Bowden, Georgina R; Ballereau, Stéphane; Jobling, Mark A (2013). Recombination Dynamics of a Human Y-Chromosomal Palindrome: Rapid GC-Biased Gene Conversion, Multi-kilobase Conversion Tracts, and Rare Inversions. Plos Genetics, 9 (7), e1003666.10.1371/journal.pgen.1003666.
5.2.
2012
Batini, Chiara; Zadik, Daniel; Hallast, Pille; Lall, Gurdeep; Jobling, Mark A (2012). Gene conversion and evolution of sex chromosomes: an NGS approach. Society of Molecular Biology & Evolution (SMBE), Dublin, Iirimaa, 23.-26. juuni 2012.
5.2.
2012
Maisano Delser, Pierpaolo; Hallast, Pille; Neumann, Rita; Ballereau, Stéphane; Jobling, Mark A (2012). X-chromosome haplotypes as markers for population historys. Society of Molecular Biology & Evolution (SMBE), Dublin, Iirimaa, 23.-26. juuni 2012.
5.2.
2012
Hallast, Pille; Bowden, Georgina; Balaresque, Patricia; Ballereau, Stéphane; Jobling, Mark A. (2012). Dynamics of intra-chromosomal recombination in human Y-chromosome palindrome P6. Society of Molecular Biology & Evolution (SMBE), Dublin, Iirimaa, 23.-26. juuni 2012.
1.1.
2011
Putku, M.; Kepp, K.; Org, E.; Sõber, S.; Comas, D.; Viigimaa, M.; Veldre, G.; Juhanson, P.; Hallast, P.; Tõnisson, N.; Shaw-Hawkins, S.; Caulfield, M.J.; Khusnutdinova, E.; Kožich, V.; Munroe, P.B.; Laan, M. (2011). Novel polymorphic AluYb8 insertion in the WNK1 gene is associated with blood pressure variation in Europeans. Human Mutation, 32 (7), 806−814.10.1002/humu.21508.
5.2.
2011
Hallast, P.; Bowden, G.; Balaresque, P.; Ballereau, S.; Jobling, M.A. (2011). Dynamics of intrachromosomal recombination in human Y-chromosome palindrome P6. Abstract book: The Biology of Genomes, Cold Spring Harbor, NY, USA, 10.05-14.05.2011.
1.1.
2010
Nagirnaja, Liina; Rull, Kristiina; Uusküla, Liis; Hallast, Pille; Grigorova, Marina; Laan, Maris. (2010). Genomics and genetics of gonadotropin beta subunit genes: unique FSHB and duplicated LHB/CGB loci. Molecular and Cellular Endocrinology, 329, 4−16.10.1016/j.mce.2010.04.024.
5.2.
2010
Putku, M.; Kepp, K.; Org, E.; Sõber, S.; Comas, D.; Viigimaa, M.; Veldre, G.; Kelgo, P.; Hallast, P.; Tõnisson, N.; Juhanson, P.; Khusnutdinova, E.; Kožich, V.; Laan, M. (2010). Novel polymorphic AluYb8 insertion in WNK1 Gene associated with blood pressure regulation. Journal of Hypertension, 28: 20th Annual Meeting of the European-Society-of-Hypertension, Oslo, Norway, June 18-21, 2010. Lippincott Williams & Wilkins, E347−E348.
2.3.
2009
Hallast, P. (2009). Human and chimpanzee Luteinizing hormone/ Chorionic Gonadotropin beta (LHB/CGB) gene clusters: diversity and divergence of young duplicated genes. (Tartu Ülikool). Tartu: Tartu Ülikooli Kirjastus.
5.2.
2009
Rull, K.; Nagirnaja, L.; Hallast, P.; Uusküla, L.; Margus, T.; Kaare, M.; Ulander, V.-M.; Aittomäki, K.; Campbell, R. K.; Laan, M. (2009). Human chorionic gonadotropin and reproductive failure: genetic variation and disease-specific gene expression. Journal of developmental origins of health and disease, 1: 6th World Congress on Developmental Origins of Health and Disease; Santiago, Tšiili; 19.-22.11.2009. Cambridge University Press, S145.10.1017/S2040174409990067.
6.1.
2009
Hallast, P.; Laan, M. (2009). Evolution of the chorionic gonadotropin beta genes in primates. In: Encyclopedia of Life Science (ELS) (1−12).. Wiley-Blackwell.10.1002/9780470015902.a0021966.
1.1.
2008
Hallast, P.; Saarela, J.; Palotie, A.; Laan, M. (2008). High divergence in primate-specific duplicated regions: Human and chimpanzee Chorionic Gonadotropin Beta genes. BMC Evolutionary Biology, 8 (195), 1−14.10.1186/1471-2148-8-195.
1.1.
2008
Rull, K.; Hallast, P.; Uusküla, L.; Jackson, J.; Punab, M.; Salumets, A.; Campbell, R.; Laan, M. (2008). Fine scale quantification of HCG beta gene transcription in human trophoblastic and non-malignant non-trophoblastic tissues. Molecular Human Reproduction, 14 (1), 23−31.10.1093/molehr/gam082.
5.1.
2008
Rull, K.; Nagirnaja, L.; Hallast, P.; Uusküla, L.; Ulander, VM.; Margus, T.; Kelgo, P.; Campbell, RC.; Aittomäki, K.; Laan, M. (2008). Expressional profile and genetic variation of chorionic gonadotropin beta genes is associated to recurrent miscarriages. Placenta, 29: IFPA2008/ 12th EPG conference, Seggau castle, Austria 10-13.09.2008. Elsevier, A46. (8).
5.2.
2008
Rull, K.; Nagirnaja, L.; Hallast, P.; Uusküla, L.; Kelgo, P.; Ulander, V.-M.; Aittomäki, K.; Campbell, R.C.; Laan, M. (2008). Human Chorionic Gonadotropin Beta genes: expression, genetic variation and reproductive failure. Abstract Book: 2nd International Conference on Gonadotropins and Their Receptors; Theobalds Park, Hertfordshire, UK; 6.07-9.07.2008.
5.2.
2008
Hallast, P.; Saarela, J.; Palotie, A.; Laan, M. (2008). Accelerated evolution of duplicated gene regions in human and chimpanzee: LHB/CGB gene family as an example. Abstract book: Genes at work on time, Toriino, Itaalia, 15.-18.10.2008.
5.2.
2008
Hallast, P.; Palotie, A.; Laan, M. (2008). The role of gene conversion in shaping the human and chimpanzee duplicated LHB/CGB gene cluster. Abstract Book: 2nd international Conference on Gonadotropins and Their Receptors; Theobalds Park, Hertfordshire, UK; 6.-9.07.2008.
1.1.
2007
Hallast, P.; Rull, K.; Laan, M. (2007). The evolution and genomic landscape of CGB1 and CGB2 genes. Molecular and Cellular Endocrinology, 260-262, 2−11.
5.2.
2007
Hallast, P.; Palotie, A; Laan, M. (2007). The role of gene conversion in shaping the human and chimpanzee duplicated LHB/CGB gene cluster. Abstract Book: The 9th International Meeting on Human Genome Variation and Complex Genome Analysis; Barcelona, Hispaania; 6.-8.09.2007.
5.2.
2007
Hallast, P.; Palotie, A.; Laan, M. (2007). Evolution by recent gene duplication: comparison of human and chimpanzee Luteinizing/ Chorionic Gonadotropin hormone beta subunit (LHB/CGB) gene cluster. Abstract Book: The Biology of Genomes; Cold Spring Harbor, USA; 8.05.-12.05.2007.
1.1.
2006
Koks, S.; Nikopensius, T.; Koido, K.; Maron, E.; Altmae, S.; Heinaste, E.; Vabrit, K.; Tammekivi, V.; Hallast, P.; Kurg, A.; Shlik, J.; Vasar, V.; Metspalu, A.; Vasar, E. (2006). Analysis of SNP profiles in patients with major depressive disorder. International Journal of Neuropsychopharmacology, 9 (2), 167−174.
5.2.
2006
Laan, M.; Hallast, P.; Grigorova, M.; Nagirnaja, L. (2006). Diversity patterns of gonadotropin hormone beta gene family: reflection of gene history, meiotic and evolutionary forces. Final programm and abstract book: 11th International Congress of Human Genetics; Brisbane, Australia; 6-10.08.2006. 193.
5.2.
2006
Hallast, P.; Laan, M. (2006). Comparison of CGB1, CGB2 and LHB genes in human and great apes. Abstract Book: The Human Genome Organisation (HUGO) 11th International Genome Meeting; Helsingi; 31.05-03.06.2006.
5.2.
2006
Laan, M.; Hallast, P.; Grigorova, M.;, Nagirnaja, L. (2006). Diversity patterns of gonadotropin hormone beta gene family: reflection of gene history, meiotic and evolutionary forces. Abstract Book: Human Genome Variation Society konverents “Copy number variation”; Helsingi; 31.05.2006.
1.1.
2005
Hallast, P.; Nagirnaja, L.; Margus, T.; Laan, M. (2005). Segmental duplications and gene conversion: Human luteinizing hormone/chorionic gonadotropin beta gene cluster. Genome Research, 15 (11), 1535−1546.
1.1.
2005
Maron, E.; Nikopensius, T.; Koks, S.; Altmae, S.; Heinaste, E.; Vabrit, K.; Tammekivi, V.; Hallast, P.; Koido, K.; Kurg, A.; Metspalu, A.; Vasar, E.; Vasar, V.; Shlik, J. (2005). Association study of 90 candidate gene polymorphisms in panic disorder. Psychiatric Genetics, 15 (1), 17−24.
1.1.
2005
Koido, K.; Kõks, S.; Nikopensius, T.; Maron, E.; Altmäe, S.; Heinaste, E.; Vabrit, K.; Tammekivi, V.; Hallast, P.; Kurg, A.; Shlik, J.; Vasar, V.; Metspalu, A.; Vasar, E. (2005). Polymorphisms in wolframin (WFS1) gene are possibly related to increased risk for mood disorders. International Journal of Neuropsychopharmacology, 8 (2), 235−244.
5.1.
2005
Maron, E.; Koks, S.; Nikopensius, T.; Altmae, S.; Heinaste, E.; Vabrit, K.; Tammekivi, V.; Hallast, P.; Koido, K.; Kurg, A.; Shlik, J.; Vasar, V.; Metspalu, A.; Vasar, E. (2005). Association and haplotype analaysis of 90 single-nucleotide polymorphisms in mood disorders. European Neuropsychopharmacology, 15, S55−S56.
5.2.
2005
Hallast, P.; Laan, M. (2005). Role of gene conversion in shaping SNP and allelic association patterns of tandem duplicated genes: LHB/CGB gene cluster. Abstract book: International Conference on Gonadotropins and Receptors, Athens, GA, USA, 13.-17.04.2005.
5.1.
2004
Maron, E.; Nikopensius, T.; Koks, S.; Altmae, S.; Heinaste, E.; Vabrit, K.; Tammekivi, V.; Hallast, P.; Koido, K.; Kurg, A.; Metapalu, A.; Vasar, E.; Vasar, V.; Shlik, J. (2004). Association study of 90 candidate genetic polymorphisms in panic disorder: Positive findings with SNPs in serotonin, cholecystokinin and dopamine related genes. European Neuropsychopharmacology, 14, S317−S317.
5.2.
2004
Laan, M.; Hallast, P.; Grigorova, M. (2004). Allelic association and SNP patterns of tandemly duplicated LHB/CGB genes are potentially shaped by gene conversion. HGM 2004 Programme and Abstract book: HGM 2004: Human Genome meeting; Berlin, Saksamaa; 4 -7 Aprill 2004. 43−43.
5.1.
2002
Kurg, A.; Nikopensius, T.; Hallast, P.; Laan, M.; Koks, S.; Slik, J.; Maron, E.; Vasar, E.; Metspalu, A. (2002). Possible association of serotonin 1B receptor and cholecystolkinin 1 receptor gene polymorphisms in bipolar and unipolar affective disorder cases in Estonia. American Journal of Human Genetics, 71 (4), 484−484.
31.05.2019

Pille Hallast

https://www.etis.ee/CV/Pille_Hallast/eng
12.07.1980
737 5009
pille.hallast@ut.ee
http://

Career

Institution and occupation
11.10.2017–...   
University of Tartu, Faculty of Medicine, Institute of Biomedicine and Translational Medicine, Senior Research Fellow of Human Molecular Genetics (1,00)
15.08.2017–...   
University of Tartu, Faculty of Medicine, Institute of Biomedicine and Translational Medicine, Senior Research Fellow of Human Molecular Genetics (1,00)
01.02.2016–...   
The Wellcome Trust Sanger Institute, visiting scientist (0,01)
01.01.2016–15.08.2017   
University of Tartu, Faculty of Biology and Geography, Institute of Molecular and Cell Biology, Senior Research Fellow of Human Molecular Genetics (1,00)
01.09.2015–31.12.2015   
University of Tartu, Faculty of Science and Technology (old), Institute of Molecular and Cell Biology, University of Tartu, Senior Research Fellowof Human Molecular Genetics (1,00)
01.01.2010–31.07.2015   
University of Leicester, post-doctoral research associate (1,00)
01.11.2009–31.10.2012   
University of Tartu, Faculty of Science and Technology (old), Institute of Molecular and Cell Biology, University of Tartu, Research Fellow of Human Molecular Genetics (1,00)
01.09.2008–31.10.2009   
University of Tartu, Faculty of Science and Technology (old), Institute of Molecular and Cell Biology, University of Tartu, Research Fellow (1,00)
01.09.2008–31.12.2008   
Estonian Biocentre, Specialist (administrator of the EU FP6 project “PROUST") (0,25)
31.05.2007–31.08.2008   
Estonian Biocentre, Specialist (administrator of the EU FP6 project “PROUST") (0,50)
01.05.2007–31.05.2007   
University of Tartu, Faculty of Biology and Geography, Institute of Molecular and Cell Biology, Specialist (0,25)
01.01.2007–31.12.2008   
Estonian Biocentre, specialist administrator of the EU FP6 project “PROUST")(0.5)
2004–2004   
University of Tartu, Faculty of Biology and Geography, Institute of Molecular and Cell Biology, laboratory assistant (1,00)
2004–2009   
University of Tartu, Faculty of Biology and Geography, Institute of Molecular and Cell Biology, Other staff (1,00)
01.01.2002–31.12.2005   
AS Asper Biotech, project manager
01.01.2000–31.12.2002   
AS Asper Biotech, laboratory assistant
 
 
Education
2006–2006   
Exchange PhD student, Finnish Genome Center, Biomedicum Helsinki, University of Helsinki, Helsinki, Finland
2004–2009   
University of Tartu, gene technology, Ph.D studies
2002–2004   
University of Tartu, gene technology, M.Sc
1998–2002   
University of Tartu, gene technology, B.Sc
1995–1998   
Hugo Treffner Gymnasium
 
 
R&D related managerial and administrative work
2004−...   
Member of the Estonian Biochemical Society
1999−...   
Member of the Estonian Society of Human Genetics
1999−...   
Member of academic students’ organization Filiae Patriae
2008−2008   
Organization of an international in silico practical course “Temporal aspects in genetic analysis” (Tartu, Estonia) as part of EU FP6 project “PROUST – The temporal dimension in functional genomics”
2008−2008   
Co-organizer of conference “Genes at work on time” (Turin, Italy) as part of EU FP6 project “PROUST – The temporal dimension in functional genomics”

Qualifications

Academic degrees
Pille Hallast, Doctor's Degree, 2009, (sup) Maris Laan, Human and chimpanzee Luteinizing Hormone/ Chorionic Gonadotropin Beta (LHB/CGB) gene clusters: diversity and divergence of young duplicated genes, University of Tartu, Faculty of Science and Technology (old), Institute of Molecular and Cell Biology, University of Tartu.
Pille Hallast, Master's Degree, 2004, (sup) Maris Laan, Geenikonversiooni roll lokaalsete alleelse aheldatuse (LD) mustrite kujundamises inimese genoomis kooriongonadotropiini beta subühiku (CGB) geeniperekonna näitel (The role of gene conversion in shaping the local pattern of linkage disequilibrium in Human Chorionic gonadotropin b-subunit gene family), University of Tartu, Faculty of Biology and Geography.
 
 
Honours & awards
2009, Pille Hallast, Kristjan Jaak's travel stipend for attending Wellcome Trust Advanced Courses “Molecular Evolution” (Hinxton, UK)
2009, Pille Hallast, The main prize from Estonian Ministry of Education and Research contest of students scientific research for PhD thesis
2008, Pille Hallast, The best poster prize at conference “The 2nd International Conference on Gonadotrophins and Their Receptors” (Hertfordshire, UK)
2007, Pille Hallast, Harald Raudsepp’s Stipend of Estonian-Revelia Academic Fund
2007, Pille Hallast, Estonian Students Fund (USA) stipend
2007, Pille Hallast, Support from Graduate School in Biomedicine and Biotechnology for attending International Conference "The Biology of Genomes” (Cold Spring Harbor, USA)
2007, Pille Hallast, Kristjan Jaak's travel stipend for attending “The 9th International Meeting on Human Genome Variation and Complex Genome Analysis" (Barcelona, Spain)
2006, Pille Hallast, Bilateral students exchange program stipend for one semester at University of Helsinki, Finland
2006, Pille Hallast, Support from Graduate School in Biomedicine and Biotechnology for attending International Conference "HUGO (The Human Genome Organisation) 11th International Genome Meeting" (Helsingi, Soome)
2006, Pille Hallast, Scholarship from Estonian Ministry of Education and Research, Kristjan Jaak stipends
2005, Pille Hallast, World Federation of Scientists stipend for 1 year
2005, Pille Hallast, Stipend from organizing committee for attending “International Conference on Gonadotropins and Receptors” (Athens, USA)
2004, Pille Hallast, Kristjan Jaak's travel stipend for attending "Human Genome Meeting 2004” (Berlin, Germany)
2003, Pille Hallast, Artur Lind stipend
2003, Pille Hallast, Harald Raudsepp’s Stipend of Estonian-Revelia Academic Fund
2002, Pille Hallast, Diploma for B. Sc thesis at Estonian Ministry of Education and Research contest of students scientific research
 
 
Field of research
FIELD OF RESEARCH: 1. Biosciences and Environment; 1.3. Genetics
 
 

Projects in progress

Completed projects

Dissertations under supervision

Publications

Category
Year
Publication
 
1.1.
2018
Shi, Wentao; Massaia, Andrea; Louzada, Sandra; Banerjee, Ruby; Hallast, Pille; Chen, Yuan; Bergström, Anders; Gu, Yong; Leonard, Steven; Quail, Michael A; Ayub, Qasim; Yang, Fengtang; Tyler-Smith, Chris; Xue, Yali (2018). Copy number variation arising from gene conversion on the human Y chromosome. Human Genetics, 137 (1), 73−83.10.1007/s00439-017-1857-9.
1.1.
2017
Maisano Delser, P.; Neumann, R.; Ballereau, S.; Hallast, P.; Batini, C.; Zadik, D.; Jobling, MA. (2017). Signatures of human European Palaeolithic expansion shown by resequencing of non-recombining X-chromosome segments. European Journal of Human Genetics, 25 (4), 485−492.10.1038/ejhg.2016.207.
1.1.
2017
Hallast, Pille; Jobling, Mark A. (2017). The Y chromosomes of the great apes. Human Genetics, 136 (5, 5), 511−528.10.1007/s00439-017-1769-8.
1.1.
2017
Batini, Chiara; Hallast, Pille; Vågene, Åshild J; Zadik, Daniel; Eriksen, Heidi A; Pamjav, Horolma; Sajantila, Antti; Wetton, Jon H; Jobling, Mark A (2017). Population resequencing of European mitochondrial genomes highlights sex-bias in Bronze Age demographic expansions. Scientific Reports, 7 (1), 12086−12086.10.1038/s41598-017-11307-9.
1.1.
2016
Hallast, Pille; Maisano Delser, Pierpaolo; Batini, Chiara; Zadik, Daniel; Rocchi, Mariano; Schempp, Werner; Tyler-Smith, Chris; Jobling, Mark A (2016). Great ape Y Chromosome and mitochondrial DNA phylogenies reflect subspecies structure and patterns of mating and dispersal. Genome Research, 26 (4), 427−439.10.1101/gr.198754.115.
1.1.
2016
de Manuel, Marc; Kuhlwilm, Martin; Frandsen, Peter; Sousa, Vitor C; Desai, Tariq; Prado-Martinez, Javier; Hernandez-Rodriguez, Jessica; Dupanloup, Isabelle; Lao, Oscar; Hallast, Pille; Schmidt, Joshua M; Heredia-Genestar, José María; Benazzo, Andrea; Barbujani, Guido; Peter, Benjamin M; Kuderna, Lukas F K; Casals, Ferran; Angedakin, Samuel; Arandjelovic, Mimi; Boesch, Christophe ... Marques-Bonet, Tomas (2016). Chimpanzee genomic diversity reveals ancient admixture with bonobos. Science (New York, N.Y.), 354 (6311), 477−481.10.1126/science.aag2602.
1.1.
2016
Haber, Marc; Mezzavilla, Massimo; Bergström, Anders; Prado-Martinez, Javier; Hallast, Pille; Saif-Ali, Riyadh; Al-Habori, Molham; Dedoussis, George; Zeggini, Eleftheria; Blue-Smith, Jason; Wells, R Spencer; Xue, Yali; Zalloua, Pierre A; Tyler-Smith, Chris (2016). Chad Genetic Diversity Reveals an African History Marked by Multiple Holocene Eurasian Migrations. American Journal of Human Genetics, 99 (6), 1316−1324.10.1016/j.ajhg.2016.10.012.
1.1.
2015
Batini, Chiara; Hallast, Pille; Zadik, Daniel; Maisano Delser, Pierpaolo; Benazzo, Andrea; Ghirotto, Silvia; Arroyo-Pardo, Eduardo; Cavalleri, Gianpiero L.; de Knijff, Peter; Dupuy, Berit Myhre; Eriksen, Heidi A.; King, Turi E.; López de Munain, Adolfo; López-Parra, Ana M.; Loutradis, Aphrodite; Milasin, Jelena; Novelletto, Andrea; Pamjav, Horolma; Sajantila, Antti; Tolun, Aslıhan ... Jobling, Mark A. (2015). Large-scale recent expansion of European patrilineages shown by population resequencing. Nature Communications, 6 (7152), x−x.10.1038/ncomms8152.
1.1.
2015
Hallast, Pille; Batini, Chiara; Zadik, Daniel; Maisano Delser, Pierpaolo; Wetton, Jon H.; Arroyo-Pardo, Eduardo; Cavalleri, Gianpiero L.; de Knijff, Peter; Destro Bisol, Giovanni; Myhre Dupuy, Berit; Eriksen, Heidi A.; Jorde, Lynn B.; King, Turi E.; Larmuseau, Maarten H.; López de Munain, Adolfo; López-Parra, Ana M.; Loutradis, Aphrodite; Milasin, Jelena; Novelletto, Andrea; Pamjav, Horolma ... Jobling, Mark A. (2015). The Y-Chromosome Tree Bursts into Leaf: 13,000 High-Confidence SNPs Covering the Majority of Known Clades. Molecular Biology and Evolution, 32 (3), 661−673.10.1093/molbev/msu327.
5.2.
2015
Hallast, Pille; Maisano Delser, Pierpaolo; Batini, Chiara; Zadik, Daniel; Schempp, Werner; Rocchi, Mariano; Tyler-Smith, Chris; Jobling, Mark A. (2015). Great ape Y chromosome diversity reflects sub-species structure and sex-biased behaviours. Abstract book: The Biology of Genomes, Cold Spring Harbor, NY, USA, 05.05-09.05.2015; Society of Molecular Biology & Evolution (SMBE), Vienna, Austria, 12.-16. juuni 2015.
5.2.
2015
Batini, Chiara; Hallast, Pille; Zadik, Daniel; Maisano Delser, Pierpaolo; Benazzo, Andrea; Ghirotto, Silvia; Arroyo-Pardo, Eduardo; Cavalleri, Gianpiero L.; de Knijff, Peter; Dupuy, Berit Myhre; Eriksen, Heidi A.; King, Turi E.; López de Munain, Adolfo; López-Parra, Ana M.; Loutradis, Aphrodite; Milasin, Jelena; Novelletto, Andrea; Pamjav, Horolma; Sajantila, Antti; Tolun, Aslıhan ... Jobling, Mark A. (2015). Contrasting patterns in the high-resolution variation of uniparental markers in European populations highlight very recent male-specific expansions. Abstract books: The Biology of Genomes, Cold Spring Harbor, NY, USA, 05.05-09.05.2015; Society of Molecular Biology & Evolution (SMBE), Vienna, Austria, 12.-16. juuni 2015.
5.2.
2014
Batini, C.; Hallast, P.; Zadik, D.; Maisano Delser, P.; Wetton, JH.; Arroyo, E.; Bodmer, W.; Cavalleri, G.; de Knijff, P.; Destro Bisol, G.; Jobling, MA. (2014). Insights into the peopling of Europe through a high‐confidence Y‐chromosome phylogeny. Conference abstract book; abstract no 58: EMBO conference "Human evolution in the genomic era: Origins, populations and phenotypes", 1 – 4 April 2014, Leicester, UK.
5.2.
2014
Zadik, D.; Batini, C.; Hallast, P.; Maisano Delser, P.; Jobling, MA. (2014). Using cross‐species sequence‐capture and next‐generation sequencing to assess the role of gene conversion in the evolution of the human sex chromosomes. Conference abstract book; abstract no 76: EMBO conference "Human evolution in the genomic era: Origins, populations and phenotypes", 1 – 4 April 2014, Leicester, UK.
5.2.
2014
Maisano Delser, P.; Neumann, R.; Hallast, P.; Batini, C.; Lall, G.; Patel, S.; Zadik, D.; Ballereau, S.; Jobling, MA. (2014). Excavating European demographic history using NGS of X‐chromosomal haplotype blocks. Conference abstract book; abstract no 80: EMBO conference "Human evolution in the genomic era: Origins, populations and phenotypes", 1 – 4 April 2014, Leicester, UK.
1.1.
2013
Hallast, Pille; Balaresque, Patricia; Bowden, Georgina R; Ballereau, Stéphane; Jobling, Mark A (2013). Recombination Dynamics of a Human Y-Chromosomal Palindrome: Rapid GC-Biased Gene Conversion, Multi-kilobase Conversion Tracts, and Rare Inversions. Plos Genetics, 9 (7), e1003666.10.1371/journal.pgen.1003666.
5.2.
2012
Batini, Chiara; Zadik, Daniel; Hallast, Pille; Lall, Gurdeep; Jobling, Mark A (2012). Gene conversion and evolution of sex chromosomes: an NGS approach. Society of Molecular Biology & Evolution (SMBE), Dublin, Iirimaa, 23.-26. juuni 2012.
5.2.
2012
Maisano Delser, Pierpaolo; Hallast, Pille; Neumann, Rita; Ballereau, Stéphane; Jobling, Mark A (2012). X-chromosome haplotypes as markers for population historys. Society of Molecular Biology & Evolution (SMBE), Dublin, Iirimaa, 23.-26. juuni 2012.
5.2.
2012
Hallast, Pille; Bowden, Georgina; Balaresque, Patricia; Ballereau, Stéphane; Jobling, Mark A. (2012). Dynamics of intra-chromosomal recombination in human Y-chromosome palindrome P6. Society of Molecular Biology & Evolution (SMBE), Dublin, Iirimaa, 23.-26. juuni 2012.
1.1.
2011
Putku, M.; Kepp, K.; Org, E.; Sõber, S.; Comas, D.; Viigimaa, M.; Veldre, G.; Juhanson, P.; Hallast, P.; Tõnisson, N.; Shaw-Hawkins, S.; Caulfield, M.J.; Khusnutdinova, E.; Kožich, V.; Munroe, P.B.; Laan, M. (2011). Novel polymorphic AluYb8 insertion in the WNK1 gene is associated with blood pressure variation in Europeans. Human Mutation, 32 (7), 806−814.10.1002/humu.21508.
5.2.
2011
Hallast, P.; Bowden, G.; Balaresque, P.; Ballereau, S.; Jobling, M.A. (2011). Dynamics of intrachromosomal recombination in human Y-chromosome palindrome P6. Abstract book: The Biology of Genomes, Cold Spring Harbor, NY, USA, 10.05-14.05.2011.
1.1.
2010
Nagirnaja, Liina; Rull, Kristiina; Uusküla, Liis; Hallast, Pille; Grigorova, Marina; Laan, Maris. (2010). Genomics and genetics of gonadotropin beta subunit genes: unique FSHB and duplicated LHB/CGB loci. Molecular and Cellular Endocrinology, 329, 4−16.10.1016/j.mce.2010.04.024.
5.2.
2010
Putku, M.; Kepp, K.; Org, E.; Sõber, S.; Comas, D.; Viigimaa, M.; Veldre, G.; Kelgo, P.; Hallast, P.; Tõnisson, N.; Juhanson, P.; Khusnutdinova, E.; Kožich, V.; Laan, M. (2010). Novel polymorphic AluYb8 insertion in WNK1 Gene associated with blood pressure regulation. Journal of Hypertension, 28: 20th Annual Meeting of the European-Society-of-Hypertension, Oslo, Norway, June 18-21, 2010. Lippincott Williams & Wilkins, E347−E348.
2.3.
2009
Hallast, P. (2009). Human and chimpanzee Luteinizing hormone/ Chorionic Gonadotropin beta (LHB/CGB) gene clusters: diversity and divergence of young duplicated genes. (Tartu Ülikool). Tartu: Tartu Ülikooli Kirjastus.
5.2.
2009
Rull, K.; Nagirnaja, L.; Hallast, P.; Uusküla, L.; Margus, T.; Kaare, M.; Ulander, V.-M.; Aittomäki, K.; Campbell, R. K.; Laan, M. (2009). Human chorionic gonadotropin and reproductive failure: genetic variation and disease-specific gene expression. Journal of developmental origins of health and disease, 1: 6th World Congress on Developmental Origins of Health and Disease; Santiago, Tšiili; 19.-22.11.2009. Cambridge University Press, S145.10.1017/S2040174409990067.
6.1.
2009
Hallast, P.; Laan, M. (2009). Evolution of the chorionic gonadotropin beta genes in primates. In: Encyclopedia of Life Science (ELS) (1−12).. Wiley-Blackwell.10.1002/9780470015902.a0021966.
1.1.
2008
Hallast, P.; Saarela, J.; Palotie, A.; Laan, M. (2008). High divergence in primate-specific duplicated regions: Human and chimpanzee Chorionic Gonadotropin Beta genes. BMC Evolutionary Biology, 8 (195), 1−14.10.1186/1471-2148-8-195.
1.1.
2008
Rull, K.; Hallast, P.; Uusküla, L.; Jackson, J.; Punab, M.; Salumets, A.; Campbell, R.; Laan, M. (2008). Fine scale quantification of HCG beta gene transcription in human trophoblastic and non-malignant non-trophoblastic tissues. Molecular Human Reproduction, 14 (1), 23−31.10.1093/molehr/gam082.
5.1.
2008
Rull, K.; Nagirnaja, L.; Hallast, P.; Uusküla, L.; Ulander, VM.; Margus, T.; Kelgo, P.; Campbell, RC.; Aittomäki, K.; Laan, M. (2008). Expressional profile and genetic variation of chorionic gonadotropin beta genes is associated to recurrent miscarriages. Placenta, 29: IFPA2008/ 12th EPG conference, Seggau castle, Austria 10-13.09.2008. Elsevier, A46. (8).
5.2.
2008
Rull, K.; Nagirnaja, L.; Hallast, P.; Uusküla, L.; Kelgo, P.; Ulander, V.-M.; Aittomäki, K.; Campbell, R.C.; Laan, M. (2008). Human Chorionic Gonadotropin Beta genes: expression, genetic variation and reproductive failure. Abstract Book: 2nd International Conference on Gonadotropins and Their Receptors; Theobalds Park, Hertfordshire, UK; 6.07-9.07.2008.
5.2.
2008
Hallast, P.; Saarela, J.; Palotie, A.; Laan, M. (2008). Accelerated evolution of duplicated gene regions in human and chimpanzee: LHB/CGB gene family as an example. Abstract book: Genes at work on time, Toriino, Itaalia, 15.-18.10.2008.
5.2.
2008
Hallast, P.; Palotie, A.; Laan, M. (2008). The role of gene conversion in shaping the human and chimpanzee duplicated LHB/CGB gene cluster. Abstract Book: 2nd international Conference on Gonadotropins and Their Receptors; Theobalds Park, Hertfordshire, UK; 6.-9.07.2008.
1.1.
2007
Hallast, P.; Rull, K.; Laan, M. (2007). The evolution and genomic landscape of CGB1 and CGB2 genes. Molecular and Cellular Endocrinology, 260-262, 2−11.
5.2.
2007
Hallast, P.; Palotie, A; Laan, M. (2007). The role of gene conversion in shaping the human and chimpanzee duplicated LHB/CGB gene cluster. Abstract Book: The 9th International Meeting on Human Genome Variation and Complex Genome Analysis; Barcelona, Hispaania; 6.-8.09.2007.
5.2.
2007
Hallast, P.; Palotie, A.; Laan, M. (2007). Evolution by recent gene duplication: comparison of human and chimpanzee Luteinizing/ Chorionic Gonadotropin hormone beta subunit (LHB/CGB) gene cluster. Abstract Book: The Biology of Genomes; Cold Spring Harbor, USA; 8.05.-12.05.2007.
1.1.
2006
Koks, S.; Nikopensius, T.; Koido, K.; Maron, E.; Altmae, S.; Heinaste, E.; Vabrit, K.; Tammekivi, V.; Hallast, P.; Kurg, A.; Shlik, J.; Vasar, V.; Metspalu, A.; Vasar, E. (2006). Analysis of SNP profiles in patients with major depressive disorder. International Journal of Neuropsychopharmacology, 9 (2), 167−174.
5.2.
2006
Laan, M.; Hallast, P.; Grigorova, M.; Nagirnaja, L. (2006). Diversity patterns of gonadotropin hormone beta gene family: reflection of gene history, meiotic and evolutionary forces. Final programm and abstract book: 11th International Congress of Human Genetics; Brisbane, Australia; 6-10.08.2006. 193.
5.2.
2006
Hallast, P.; Laan, M. (2006). Comparison of CGB1, CGB2 and LHB genes in human and great apes. Abstract Book: The Human Genome Organisation (HUGO) 11th International Genome Meeting; Helsingi; 31.05-03.06.2006.
5.2.
2006
Laan, M.; Hallast, P.; Grigorova, M.;, Nagirnaja, L. (2006). Diversity patterns of gonadotropin hormone beta gene family: reflection of gene history, meiotic and evolutionary forces. Abstract Book: Human Genome Variation Society konverents “Copy number variation”; Helsingi; 31.05.2006.
1.1.
2005
Hallast, P.; Nagirnaja, L.; Margus, T.; Laan, M. (2005). Segmental duplications and gene conversion: Human luteinizing hormone/chorionic gonadotropin beta gene cluster. Genome Research, 15 (11), 1535−1546.
1.1.
2005
Maron, E.; Nikopensius, T.; Koks, S.; Altmae, S.; Heinaste, E.; Vabrit, K.; Tammekivi, V.; Hallast, P.; Koido, K.; Kurg, A.; Metspalu, A.; Vasar, E.; Vasar, V.; Shlik, J. (2005). Association study of 90 candidate gene polymorphisms in panic disorder. Psychiatric Genetics, 15 (1), 17−24.
1.1.
2005
Koido, K.; Kõks, S.; Nikopensius, T.; Maron, E.; Altmäe, S.; Heinaste, E.; Vabrit, K.; Tammekivi, V.; Hallast, P.; Kurg, A.; Shlik, J.; Vasar, V.; Metspalu, A.; Vasar, E. (2005). Polymorphisms in wolframin (WFS1) gene are possibly related to increased risk for mood disorders. International Journal of Neuropsychopharmacology, 8 (2), 235−244.
5.1.
2005
Maron, E.; Koks, S.; Nikopensius, T.; Altmae, S.; Heinaste, E.; Vabrit, K.; Tammekivi, V.; Hallast, P.; Koido, K.; Kurg, A.; Shlik, J.; Vasar, V.; Metspalu, A.; Vasar, E. (2005). Association and haplotype analaysis of 90 single-nucleotide polymorphisms in mood disorders. European Neuropsychopharmacology, 15, S55−S56.
5.2.
2005
Hallast, P.; Laan, M. (2005). Role of gene conversion in shaping SNP and allelic association patterns of tandem duplicated genes: LHB/CGB gene cluster. Abstract book: International Conference on Gonadotropins and Receptors, Athens, GA, USA, 13.-17.04.2005.
5.1.
2004
Maron, E.; Nikopensius, T.; Koks, S.; Altmae, S.; Heinaste, E.; Vabrit, K.; Tammekivi, V.; Hallast, P.; Koido, K.; Kurg, A.; Metapalu, A.; Vasar, E.; Vasar, V.; Shlik, J. (2004). Association study of 90 candidate genetic polymorphisms in panic disorder: Positive findings with SNPs in serotonin, cholecystokinin and dopamine related genes. European Neuropsychopharmacology, 14, S317−S317.
5.2.
2004
Laan, M.; Hallast, P.; Grigorova, M. (2004). Allelic association and SNP patterns of tandemly duplicated LHB/CGB genes are potentially shaped by gene conversion. HGM 2004 Programme and Abstract book: HGM 2004: Human Genome meeting; Berlin, Saksamaa; 4 -7 Aprill 2004. 43−43.
5.1.
2002
Kurg, A.; Nikopensius, T.; Hallast, P.; Laan, M.; Koks, S.; Slik, J.; Maron, E.; Vasar, E.; Metspalu, A. (2002). Possible association of serotonin 1B receptor and cholecystolkinin 1 receptor gene polymorphisms in bipolar and unipolar affective disorder cases in Estonia. American Journal of Human Genetics, 71 (4), 484−484.
31.05.2019
Detailne otsing
  • Leitud 8 kirjet
ProgrammLiikNumberNimiProjekti algusProjekti lõppVastutav täitjaAsutusFinantseerijapoolne rahastamine
PUT; PUT_SPPUT1036Dünaamilised sugu-kromosoomid ja meeste viljatus: uue-generatsiooni lähenemine01.01.201605.06.2021Pille HallastTartu Ülikool, Loodus- ja täppisteaduste valdkond, molekulaar- ja rakubioloogia instituut; Tartu Ülikool, Meditsiiniteaduste valdkond, bio- ja siirdemeditsiini instituut133 200,00 EUR
MUULSSG-CT-2006-037654Funktsionaalse genoomika ajaline dimensioon (PROUST)01.01.200728.02.2009Maris LaanEesti Biokeskus50 331,32 EUR
SFSF0182721s06Genoomi ülesehitus ja varieeruvus: evolutsiooni- ja rekombinatsiooni protsesside peegeldus ning seos normaalse ja patoloogilise funktsiooniga01.01.200631.12.2011Maris LaanTartu Ülikool, Bioloogia-geograafiateaduskond; Tartu Ülikool, Loodus- ja tehnoloogiateaduskond, Tartu Ülikooli Molekulaar- ja Rakubioloogia Instituut; Tartu Ülikool, Loodus- ja tehnoloogiateaduskond418 383,64 EUR
SFSF0182582As03Inimese Genoom II01.01.200331.12.2007Andres MetspaluTartu Ülikool, Bioloogia-geograafiateaduskond328 505,88 EUR
ETFETF7471INIMESE KASVUHORMOONI/ KOORIONI SOMATOMAMMOTROPIINI GENOOMI KLASTER: varieeruvuse ja ekspressiooni seos üsasisese kasvu, loote-ema metabolismi ja soodumusega kardiovaskulaarhaigustele täiskasvanueas. 01.01.200831.12.2011Maris LaanTartu Ülikool, Bioloogia-geograafiateaduskond; Tartu Ülikool, Loodus- ja tehnoloogiateaduskond, Tartu Ülikooli Molekulaar- ja Rakubioloogia Instituut; Tartu Ülikool, Loodus- ja tehnoloogiateaduskond119 028,97 EUR
ETFETF5796Inimese lutropiini/kooriongonadotropiini ß-subühiku genoomiklaster (I) Genoomne varieeruvus, LD struktuur ning mittehomoloogilise ristsiirde ja geenikonversiooni roll nende kujundamisel.01.01.200431.12.2007Maris LaanTartu Ülikool, Bioloogia-geograafiateaduskond54 007,15 EUR
SFSF0180022s12Inimese reproduktiiv- ja metaboolne funktsioon: genoomi ekspressioon, varieeruvus ja pleiotroopsed effektid01.01.201231.12.2014Maris LaanTartu Ülikool, Loodus- ja tehnoloogiateaduskond, Tartu Ülikooli Molekulaar- ja Rakubioloogia Instituut374 340,00 EUR
IUTIUT34-12Inimese reproduktiivset edukust määravad geneetilised ja molekulaarsed tegurid01.01.201531.12.2020Maris LaanTartu Ülikool, Loodus- ja täppisteaduste valdkond, molekulaar- ja rakubioloogia instituut; Tartu Ülikool, Meditsiiniteaduste valdkond, bio- ja siirdemeditsiini instituut704 000,00 EUR