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"Muu" projekt LSHB-CT-2007-037592
LSHB-CT-2007-037592 "Applied venomics of the cone snail species Conus consors for the accelerated, cheaper, safer and more ethical production of innovative biomedical drugs (1.02.2007−31.01.2012)", Maido Remm, Eesti Biokeskus.
LSHB-CT-2007-037592
LSHB-CT-2007-037592
Applied venomics of the cone snail species Conus consors for the accelerated, cheaper, safer and more ethical production of innovative biomedical drugs
Applied venomics of the cone snail species Conus consors for the accelerated, cheaper, safer and more ethical production of innovative biomedical drugs
1.02.2007
31.01.2012
Teadus- ja arendusprojekt
Muu
ETIS klassifikaatorAlamvaldkondCERCS klassifikaatorFrascati Manual’i klassifikaatorProtsent
3. Terviseuuringud3.11. Terviseuuringutega seotud uuringud, näiteks biokeemia, geneetika, mikrobioloogia, biotehnoloogia, molekulaarbioloogia, rakubioloogia, biofüüsika ja bioinformaatikaB110 Bioinformaatika, meditsiiniinformaatika, biomatemaatika, biomeetrika 3.1. Biomeditsiin (anatoomia, tsütoloogia, füsioloogia, geneetika, farmaatsia, farmakoloogia, kliiniline keemia, kliiniline mikrobioloogia, patoloogia)100,0
AsutusRollPeriood
Eesti Biokeskuspartner01.02.2007−31.01.2012
AsutusRiikTüüp
European Commision
PerioodSumma
01.02.2007−31.01.20127 825 506,00 EEK (500 140,99 EUR)
500 140,99 EUR
FP6 Integrated Project

"CONCO is an innovative post-genomic project dedicated to the discovery and development of novel biopharmaceuticals generated by the broad biodiversity of cone snails. The project aims at characterising from the genomic up to potential therapeutic properties all putative bioactive compounds that can be synthesised by a cone snail species. The genome and transcriptome of Conus consors will be exhaustively studied. Large amounts of venom will be fractionated and submitted to proteomic studies to generate a biochemically characterised ""natural library"" of compounds. Large scale synthesis of each identified candidate will be achieved to form a ""synthetic library"" of compounds. The biological activity of these two libraries will be investigated on a panel of physiological targets that are recognised of therapeutic value. Selected hits will be optimised and validated in vivo. A publicly accessible web-based database will be developed and annotated to integrate and share all the knowledge generated by the project."
"CONCO is an innovative post-genomic project dedicated to the discovery and development of novel biopharmaceuticals generated by the broad biodiversity of cone snails. The project aims at characterising from the genomic up to potential therapeutic properties all putative bioactive compounds that can be synthesised by a cone snail species. The genome and transcriptome of Conus consors will be exhaustively studied. Large amounts of venom will be fractionated and submitted to proteomic studies to generate a biochemically characterised ""natural library"" of compounds. Large scale synthesis of each identified candidate will be achieved to form a ""synthetic library"" of compounds. The biological activity of these two libraries will be investigated on a panel of physiological targets that are recognised of therapeutic value. Selected hits will be optimised and validated in vivo. A publicly accessible web-based database will be developed and annotated to integrate and share all the knowledge generated by the project."
www.conco.eu