Astro-particle cosmic ray experiments and the Large Hadron collider are going in the next years to explore the TeV energy range; one of the main goals is uncovering the nature of Dark Matter. Nontrivial phenomenological and theoretical work will be needed to understand the meaning of the data, because new physics will likely show up mixed with ordinary Standard Model processes and astrophysical sources. For example, detection of TeV-scale neutrinos from the sun will allow us to infer the contribution to the total solar energy flow due to Dark Matter annihilations, compared to the dominant contribution of nuclear fusion recently probed by MeV-scale neutrinos.