See veebileht kasutab küpsiseid kasutaja sessiooni andmete hoidmiseks. Veebilehe kasutamisega nõustute ETISe kasutustingimustega. Loe rohkem
Olen nõus
"Muu" projekt SARLA11091E
SARLA11091E "EUROCORES/ EuroEPINOMICS (1.06.2011−31.05.2014)", Tiina Talvik, Tartu Ülikool, Tartu Ülikool, Arstiteaduskond, Lastekliinik.
SARLA11091E
EUROCORES/ EuroEPINOMICS
EUROCORES/ EuroEPINOMICS
1.06.2011
31.05.2014
Teadus- ja arendusprojekt
Muu
ValdkondAlamvaldkondCERCS erialaFrascati Manual’i erialaProtsent
1. Bio- ja keskkonnateadused1.3. GeneetikaB220 Geneetika, tsütogeneetika 1.5. Bioteadused (bioloogia, botaanika, bakterioloogia, mikrobioloogia, zooloogia, entomoloogia, geneetika, biokeemia, biofüüsika jt40,0
3. Terviseuuringud3.7. Kliiniline meditsiinB640 Neuroloogia, neuropsühholoogia, neurofüsioloogia 3.2. Kliiniline meditsiin (anestesioloogia, pediaatria, sünnitusabi ja günekoloogia, sisehaigused, kirurgia, stomatoloogia, neuroloogia, psühhiaatria, radioloogia, terapeutika, otorinolarüngoloogia, oftalmoloogia)60,0
AsutusRollPeriood
Tartu Ülikoolpartner01.06.2011−31.05.2014
Tartu Ülikool, Arstiteaduskond, Lastekliinikpartner01.06.2011−31.05.2014
AsutusRiikTüüp
Sihtasutus Eesti Teadusfond
PerioodSumma
01.06.2011−31.05.2014143 801,00 EUR
143 801,00 EUR
0,00 EUR
ESF_EUROCORES

This Collaborative Research Project (CRP) aims to decipher the genetic basis of many rare epileptic syndromes(RES )using a multinational large-scale approach, bringing together the expertise of epileptologists with access to large patient cohorts and molecular genetic teams with a vast experience in locus and gene identification. Collectively, this team of researchers will recruit the largest cohort of patients with RES to date and, for the first time, collect comprehensive clinical, electrophysiological and genealogical data in a standardized way. Novel genes for seizure disorders will be identified in 50 large families and 500 sporadic cases using broad range of technologies including large-scale CNV analysis and next-generation sequencing techniques. These technologies will be applied in a systematic genetic workflow to streamline analysis efficiency. Finally, genotype-phenotype correlation will be performed to identify novel disease entities based on genetic findings. The interdisciplinary character and scale of this initiative comprising 10 European partners and 4 international partners is unprecedented. This CRP has the ambitious goal to identify the genetic basis in a substantial fraction of patients with Rare Epilepsy Syndromes. Therefore, we expect this CRP to represent a milestone in genetic research in seizure disorders.
This Collaborative Research Project (CRP) aims to decipher the genetic basis of many rare epileptic syndromes(RES )using a multinational large-scale approach, bringing together the expertise of epileptologists with access to large patient cohorts and molecular genetic teams with a vast experience in locus and gene identification. Collectively, this team of researchers will recruit the largest cohort of patients with RES to date and, for the first time, collect comprehensive clinical, electrophysiological and genealogical data in a standardized way. Novel genes for seizure disorders will be identified in 50 large families and 500 sporadic cases using broad range of technologies including large-scale CNV analysis and next-generation sequencing techniques. These technologies will be applied in a systematic genetic workflow to streamline analysis efficiency. Finally, genotype-phenotype correlation will be performed to identify novel disease entities based on genetic findings. The interdisciplinary character and scale of this initiative comprising 10 European partners and 4 international partners is unprecedented. This CRP has the ambitious goal to identify the genetic basis in a substantial fraction of patients with Rare Epilepsy Syndromes. Therefore, we expect this CRP to represent a milestone in genetic research in seizure disorders.
TegevusProtsent
Alusuuring30,0
Rakendusuuring40,0
Katse- ja arendustöö30,0